Amino acid dipepetide frequency for Termite gut associated microvirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.905AlaAla: 2.905 ± 1.985
0.726AlaCys: 0.726 ± 0.616
2.179AlaAsp: 2.179 ± 0.967
3.631AlaGlu: 3.631 ± 1.941
1.452AlaPhe: 1.452 ± 1.233
4.357AlaGly: 4.357 ± 3.381
0.0AlaHis: 0.0 ± 0.0
2.179AlaIle: 2.179 ± 0.601
4.357AlaLys: 4.357 ± 3.381
7.262AlaLeu: 7.262 ± 1.382
2.179AlaMet: 2.179 ± 0.967
2.905AlaAsn: 2.905 ± 1.172
4.357AlaPro: 4.357 ± 3.179
4.357AlaGln: 4.357 ± 2.61
2.905AlaArg: 2.905 ± 1.192
6.536AlaSer: 6.536 ± 3.054
2.179AlaThr: 2.179 ± 1.399
3.631AlaVal: 3.631 ± 1.134
0.0AlaTrp: 0.0 ± 0.0
6.536AlaTyr: 6.536 ± 1.812
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.452CysPhe: 1.452 ± 0.596
1.452CysGly: 1.452 ± 1.233
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.452CysLys: 1.452 ± 1.233
0.726CysLeu: 0.726 ± 0.616
0.726CysMet: 0.726 ± 0.975
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.726CysGln: 0.726 ± 0.616
1.452CysArg: 1.452 ± 1.194
0.0CysSer: 0.0 ± 0.0
0.726CysThr: 0.726 ± 0.616
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.905AspAla: 2.905 ± 2.062
0.0AspCys: 0.0 ± 0.0
5.084AspAsp: 5.084 ± 4.087
1.452AspGlu: 1.452 ± 1.167
5.084AspPhe: 5.084 ± 0.868
5.084AspGly: 5.084 ± 1.378
0.726AspHis: 0.726 ± 0.616
2.179AspIle: 2.179 ± 0.974
0.726AspLys: 0.726 ± 1.081
7.262AspLeu: 7.262 ± 4.375
2.179AspMet: 2.179 ± 1.994
0.0AspAsn: 0.0 ± 0.0
2.179AspPro: 2.179 ± 1.206
2.905AspGln: 2.905 ± 1.989
1.452AspArg: 1.452 ± 1.278
6.536AspSer: 6.536 ± 2.365
3.631AspThr: 3.631 ± 1.762
5.084AspVal: 5.084 ± 0.835
0.726AspTrp: 0.726 ± 0.497
5.084AspTyr: 5.084 ± 1.611
0.0AspXaa: 0.0 ± 0.0
Glu
2.179GluAla: 2.179 ± 1.092
0.0GluCys: 0.0 ± 0.0
2.905GluAsp: 2.905 ± 1.374
0.726GluGlu: 0.726 ± 0.497
2.179GluPhe: 2.179 ± 1.849
2.905GluGly: 2.905 ± 2.062
2.179GluHis: 2.179 ± 0.909
2.179GluIle: 2.179 ± 2.233
0.726GluLys: 0.726 ± 1.081
5.81GluLeu: 5.81 ± 1.531
0.0GluMet: 0.0 ± 0.0
0.726GluAsn: 0.726 ± 0.709
1.452GluPro: 1.452 ± 2.162
0.726GluGln: 0.726 ± 1.081
2.905GluArg: 2.905 ± 0.743
1.452GluSer: 1.452 ± 1.032
2.905GluThr: 2.905 ± 1.29
4.357GluVal: 4.357 ± 1.246
2.179GluTrp: 2.179 ± 1.305
2.905GluTyr: 2.905 ± 1.192
0.0GluXaa: 0.0 ± 0.0
Phe
4.357PheAla: 4.357 ± 1.202
1.452PheCys: 1.452 ± 1.233
2.179PheAsp: 2.179 ± 0.909
2.179PheGlu: 2.179 ± 1.492
2.905PhePhe: 2.905 ± 1.808
3.631PheGly: 3.631 ± 1.602
0.0PheHis: 0.0 ± 0.0
3.631PheIle: 3.631 ± 1.602
0.726PheLys: 0.726 ± 0.497
3.631PheLeu: 3.631 ± 1.944
2.179PheMet: 2.179 ± 0.964
1.452PheAsn: 1.452 ± 0.596
2.905PhePro: 2.905 ± 1.988
1.452PheGln: 1.452 ± 0.596
3.631PheArg: 3.631 ± 1.924
4.357PheSer: 4.357 ± 1.577
2.905PheThr: 2.905 ± 1.689
1.452PheVal: 1.452 ± 0.596
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.357GlyAla: 4.357 ± 3.381
0.726GlyCys: 0.726 ± 0.497
4.357GlyAsp: 4.357 ± 1.934
3.631GlyGlu: 3.631 ± 1.229
4.357GlyPhe: 4.357 ± 1.731
9.441GlyGly: 9.441 ± 2.836
1.452GlyHis: 1.452 ± 1.045
2.905GlyIle: 2.905 ± 1.006
0.726GlyLys: 0.726 ± 0.616
3.631GlyLeu: 3.631 ± 1.454
0.726GlyMet: 0.726 ± 0.497
2.179GlyAsn: 2.179 ± 0.601
2.179GlyPro: 2.179 ± 1.175
7.262GlyGln: 7.262 ± 1.382
8.715GlyArg: 8.715 ± 1.701
2.905GlySer: 2.905 ± 0.983
4.357GlyThr: 4.357 ± 1.681
3.631GlyVal: 3.631 ± 1.113
0.726GlyTrp: 0.726 ± 0.497
2.179GlyTyr: 2.179 ± 1.492
0.0GlyXaa: 0.0 ± 0.0
His
1.452HisAla: 1.452 ± 1.194
0.0HisCys: 0.0 ± 0.0
1.452HisAsp: 1.452 ± 1.233
1.452HisGlu: 1.452 ± 1.256
2.179HisPhe: 2.179 ± 1.175
2.179HisGly: 2.179 ± 0.909
0.726HisHis: 0.726 ± 0.497
2.905HisIle: 2.905 ± 1.488
1.452HisLys: 1.452 ± 1.045
0.726HisLeu: 0.726 ± 0.616
0.0HisMet: 0.0 ± 0.0
0.726HisAsn: 0.726 ± 0.616
4.357HisPro: 4.357 ± 1.555
0.0HisGln: 0.0 ± 0.0
2.905HisArg: 2.905 ± 0.983
3.631HisSer: 3.631 ± 1.924
0.726HisThr: 0.726 ± 0.616
0.726HisVal: 0.726 ± 0.497
0.726HisTrp: 0.726 ± 0.497
2.179HisTyr: 2.179 ± 1.106
0.0HisXaa: 0.0 ± 0.0
Ile
3.631IleAla: 3.631 ± 2.031
1.452IleCys: 1.452 ± 1.194
0.726IleAsp: 0.726 ± 0.497
4.357IleGlu: 4.357 ± 1.476
0.726IlePhe: 0.726 ± 0.497
3.631IleGly: 3.631 ± 1.113
1.452IleHis: 1.452 ± 0.687
2.179IleIle: 2.179 ± 1.243
0.0IleLys: 0.0 ± 0.0
4.357IleLeu: 4.357 ± 1.227
0.0IleMet: 0.0 ± 0.0
2.179IleAsn: 2.179 ± 1.849
2.905IlePro: 2.905 ± 1.376
2.905IleGln: 2.905 ± 0.743
2.905IleArg: 2.905 ± 1.172
1.452IleSer: 1.452 ± 0.995
4.357IleThr: 4.357 ± 1.246
4.357IleVal: 4.357 ± 1.817
0.726IleTrp: 0.726 ± 0.616
0.726IleTyr: 0.726 ± 0.497
0.0IleXaa: 0.0 ± 0.0
Lys
2.905LysAla: 2.905 ± 1.657
0.726LysCys: 0.726 ± 0.616
0.726LysAsp: 0.726 ± 0.497
2.179LysGlu: 2.179 ± 1.206
0.726LysPhe: 0.726 ± 0.497
2.905LysGly: 2.905 ± 1.251
2.179LysHis: 2.179 ± 0.909
0.726LysIle: 0.726 ± 0.497
2.179LysLys: 2.179 ± 2.486
3.631LysLeu: 3.631 ± 1.803
0.0LysMet: 0.0 ± 0.436
0.726LysAsn: 0.726 ± 0.709
3.631LysPro: 3.631 ± 4.042
0.726LysGln: 0.726 ± 0.709
2.905LysArg: 2.905 ± 0.888
2.179LysSer: 2.179 ± 1.521
0.726LysThr: 0.726 ± 0.616
0.726LysVal: 0.726 ± 1.139
0.0LysTrp: 0.0 ± 0.0
1.452LysTyr: 1.452 ± 1.233
0.0LysXaa: 0.0 ± 0.0
Leu
3.631LeuAla: 3.631 ± 1.113
0.0LeuCys: 0.0 ± 0.0
9.441LeuAsp: 9.441 ± 3.717
1.452LeuGlu: 1.452 ± 1.233
2.905LeuPhe: 2.905 ± 1.29
7.262LeuGly: 7.262 ± 1.033
4.357LeuHis: 4.357 ± 1.989
1.452LeuIle: 1.452 ± 0.995
3.631LeuLys: 3.631 ± 1.667
5.084LeuLeu: 5.084 ± 1.696
0.726LeuMet: 0.726 ± 0.616
2.179LeuAsn: 2.179 ± 0.601
9.441LeuPro: 9.441 ± 1.676
7.262LeuGln: 7.262 ± 2.271
7.262LeuArg: 7.262 ± 3.052
6.536LeuSer: 6.536 ± 2.326
3.631LeuThr: 3.631 ± 2.23
4.357LeuVal: 4.357 ± 1.577
1.452LeuTrp: 1.452 ± 1.233
5.81LeuTyr: 5.81 ± 1.29
0.0LeuXaa: 0.0 ± 0.0
Met
2.179MetAla: 2.179 ± 1.072
0.0MetCys: 0.0 ± 0.0
1.452MetAsp: 1.452 ± 0.995
0.0MetGlu: 0.0 ± 0.0
1.452MetPhe: 1.452 ± 1.256
0.0MetGly: 0.0 ± 0.0
0.726MetHis: 0.726 ± 0.497
0.0MetIle: 0.0 ± 0.0
1.452MetLys: 1.452 ± 1.045
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.452MetAsn: 1.452 ± 0.815
2.179MetPro: 2.179 ± 0.974
0.0MetGln: 0.0 ± 0.0
2.179MetArg: 2.179 ± 1.206
1.452MetSer: 1.452 ± 0.596
0.726MetThr: 0.726 ± 0.616
0.726MetVal: 0.726 ± 0.709
0.726MetTrp: 0.726 ± 0.709
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.357AsnAla: 4.357 ± 2.533
0.726AsnCys: 0.726 ± 0.616
3.631AsnAsp: 3.631 ± 1.346
1.452AsnGlu: 1.452 ± 0.995
0.726AsnPhe: 0.726 ± 0.709
2.179AsnGly: 2.179 ± 0.601
0.0AsnHis: 0.0 ± 0.0
0.726AsnIle: 0.726 ± 0.616
2.905AsnLys: 2.905 ± 1.689
3.631AsnLeu: 3.631 ± 1.556
0.0AsnMet: 0.0 ± 0.0
0.726AsnAsn: 0.726 ± 0.497
2.179AsnPro: 2.179 ± 0.967
3.631AsnGln: 3.631 ± 2.68
5.084AsnArg: 5.084 ± 1.512
3.631AsnSer: 3.631 ± 1.454
1.452AsnThr: 1.452 ± 0.596
0.726AsnVal: 0.726 ± 0.497
0.726AsnTrp: 0.726 ± 0.616
0.726AsnTyr: 0.726 ± 0.709
0.0AsnXaa: 0.0 ± 0.0
Pro
5.084ProAla: 5.084 ± 4.174
0.726ProCys: 0.726 ± 0.616
5.81ProAsp: 5.81 ± 3.015
5.81ProGlu: 5.81 ± 1.487
2.179ProPhe: 2.179 ± 0.909
6.536ProGly: 6.536 ± 2.245
2.905ProHis: 2.905 ± 1.991
5.084ProIle: 5.084 ± 2.024
0.726ProLys: 0.726 ± 1.081
7.262ProLeu: 7.262 ± 1.639
0.0ProMet: 0.0 ± 0.0
3.631ProAsn: 3.631 ± 1.454
5.084ProPro: 5.084 ± 3.115
0.726ProGln: 0.726 ± 1.139
1.452ProArg: 1.452 ± 2.278
10.893ProSer: 10.893 ± 4.964
3.631ProThr: 3.631 ± 2.23
7.988ProVal: 7.988 ± 3.197
1.452ProTrp: 1.452 ± 0.687
2.905ProTyr: 2.905 ± 1.05
0.0ProXaa: 0.0 ± 0.0
Gln
3.631GlnAla: 3.631 ± 1.346
0.0GlnCys: 0.0 ± 0.0
0.726GlnAsp: 0.726 ± 0.497
3.631GlnGlu: 3.631 ± 2.114
1.452GlnPhe: 1.452 ± 0.596
1.452GlnGly: 1.452 ± 1.045
2.179GlnHis: 2.179 ± 0.601
0.726GlnIle: 0.726 ± 0.709
0.726GlnLys: 0.726 ± 0.497
4.357GlnLeu: 4.357 ± 1.301
0.0GlnMet: 0.0 ± 0.0
4.357GlnAsn: 4.357 ± 1.934
5.084GlnPro: 5.084 ± 1.776
1.452GlnGln: 1.452 ± 0.687
4.357GlnArg: 4.357 ± 1.633
5.084GlnSer: 5.084 ± 1.611
2.179GlnThr: 2.179 ± 0.909
4.357GlnVal: 4.357 ± 3.105
1.452GlnTrp: 1.452 ± 0.687
0.726GlnTyr: 0.726 ± 0.616
0.0GlnXaa: 0.0 ± 0.0
Arg
2.179ArgAla: 2.179 ± 1.092
0.726ArgCys: 0.726 ± 1.139
3.631ArgAsp: 3.631 ± 1.924
1.452ArgGlu: 1.452 ± 1.256
2.905ArgPhe: 2.905 ± 1.338
2.905ArgGly: 2.905 ± 1.251
2.905ArgHis: 2.905 ± 3.25
8.715ArgIle: 8.715 ± 2.914
4.357ArgLys: 4.357 ± 4.028
6.536ArgLeu: 6.536 ± 2.922
2.179ArgMet: 2.179 ± 0.992
2.179ArgAsn: 2.179 ± 1.399
7.262ArgPro: 7.262 ± 1.605
3.631ArgGln: 3.631 ± 1.216
7.262ArgArg: 7.262 ± 2.845
8.715ArgSer: 8.715 ± 2.871
2.905ArgThr: 2.905 ± 2.103
2.905ArgVal: 2.905 ± 0.743
1.452ArgTrp: 1.452 ± 1.419
4.357ArgTyr: 4.357 ± 0.808
0.0ArgXaa: 0.0 ± 0.0
Ser
5.084SerAla: 5.084 ± 2.267
0.0SerCys: 0.0 ± 0.0
9.441SerAsp: 9.441 ± 4.474
2.905SerGlu: 2.905 ± 1.078
4.357SerPhe: 4.357 ± 2.301
6.536SerGly: 6.536 ± 1.782
2.905SerHis: 2.905 ± 1.05
3.631SerIle: 3.631 ± 1.113
1.452SerLys: 1.452 ± 0.995
8.715SerLeu: 8.715 ± 1.511
0.726SerMet: 0.726 ± 0.939
4.357SerAsn: 4.357 ± 2.281
8.715SerPro: 8.715 ± 1.548
2.179SerGln: 2.179 ± 0.601
7.988SerArg: 7.988 ± 4.871
9.441SerSer: 9.441 ± 4.54
3.631SerThr: 3.631 ± 1.803
2.905SerVal: 2.905 ± 2.103
0.726SerTrp: 0.726 ± 0.497
1.452SerTyr: 1.452 ± 0.687
0.0SerXaa: 0.0 ± 0.0
Thr
5.084ThrAla: 5.084 ± 1.195
0.726ThrCys: 0.726 ± 0.616
0.726ThrAsp: 0.726 ± 0.497
2.179ThrGlu: 2.179 ± 1.106
2.179ThrPhe: 2.179 ± 1.106
2.905ThrGly: 2.905 ± 1.989
0.726ThrHis: 0.726 ± 0.616
4.357ThrIle: 4.357 ± 1.817
1.452ThrLys: 1.452 ± 1.045
3.631ThrLeu: 3.631 ± 2.306
0.726ThrMet: 0.726 ± 1.139
1.452ThrAsn: 1.452 ± 1.233
7.988ThrPro: 7.988 ± 2.612
2.179ThrGln: 2.179 ± 0.974
3.631ThrArg: 3.631 ± 1.715
2.905ThrSer: 2.905 ± 1.338
3.631ThrThr: 3.631 ± 2.487
1.452ThrVal: 1.452 ± 0.596
0.726ThrTrp: 0.726 ± 0.497
2.179ThrTyr: 2.179 ± 1.521
0.0ThrXaa: 0.0 ± 0.0
Val
4.357ValAla: 4.357 ± 1.16
0.0ValCys: 0.0 ± 0.0
2.905ValAsp: 2.905 ± 2.333
2.179ValGlu: 2.179 ± 1.245
2.179ValPhe: 2.179 ± 1.492
3.631ValGly: 3.631 ± 1.145
2.179ValHis: 2.179 ± 0.909
0.0ValIle: 0.0 ± 0.0
2.905ValLys: 2.905 ± 1.192
5.084ValLeu: 5.084 ± 2.077
2.905ValMet: 2.905 ± 1.078
3.631ValAsn: 3.631 ± 0.965
4.357ValPro: 4.357 ± 1.034
2.179ValGln: 2.179 ± 1.092
5.084ValArg: 5.084 ± 3.175
2.179ValSer: 2.179 ± 1.305
3.631ValThr: 3.631 ± 1.829
2.179ValVal: 2.179 ± 0.601
0.726ValTrp: 0.726 ± 0.497
2.905ValTyr: 2.905 ± 0.743
0.0ValXaa: 0.0 ± 0.0
Trp
1.452TrpAla: 1.452 ± 0.995
0.726TrpCys: 0.726 ± 0.616
0.726TrpAsp: 0.726 ± 0.497
0.0TrpGlu: 0.0 ± 0.0
0.726TrpPhe: 0.726 ± 0.497
0.726TrpGly: 0.726 ± 0.616
1.452TrpHis: 1.452 ± 0.995
0.726TrpIle: 0.726 ± 0.497
0.0TrpLys: 0.0 ± 0.0
0.726TrpLeu: 0.726 ± 0.709
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.726TrpPro: 0.726 ± 0.709
0.726TrpGln: 0.726 ± 0.709
1.452TrpArg: 1.452 ± 1.419
1.452TrpSer: 1.452 ± 0.687
1.452TrpThr: 1.452 ± 1.233
0.726TrpVal: 0.726 ± 0.709
0.0TrpTrp: 0.0 ± 0.0
0.726TrpTyr: 0.726 ± 0.497
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.905TyrAla: 2.905 ± 0.743
0.0TyrCys: 0.0 ± 0.0
2.179TyrAsp: 2.179 ± 1.092
0.726TyrGlu: 0.726 ± 1.081
2.905TyrPhe: 2.905 ± 1.078
0.726TyrGly: 0.726 ± 0.616
1.452TyrHis: 1.452 ± 1.233
0.726TyrIle: 0.726 ± 0.616
0.726TyrLys: 0.726 ± 0.497
5.81TyrLeu: 5.81 ± 1.687
0.726TyrMet: 0.726 ± 0.616
4.357TyrAsn: 4.357 ± 1.578
2.905TyrPro: 2.905 ± 1.006
2.905TyrGln: 2.905 ± 1.374
3.631TyrArg: 3.631 ± 1.454
5.81TyrSer: 5.81 ± 1.893
1.452TyrThr: 1.452 ± 0.596
2.905TyrVal: 2.905 ± 1.192
0.0TyrTrp: 0.0 ± 0.0
0.726TyrTyr: 0.726 ± 1.139
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1378 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski