Amino acid dipepetide frequency for Thin paspalum asymptomatic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.638AlaAla: 7.638 ± 2.986
0.546AlaCys: 0.546 ± 0.335
3.273AlaAsp: 3.273 ± 1.258
3.819AlaGlu: 3.819 ± 1.049
1.637AlaPhe: 1.637 ± 0.705
3.819AlaGly: 3.819 ± 1.405
1.091AlaHis: 1.091 ± 0.816
3.819AlaIle: 3.819 ± 0.764
4.91AlaLys: 4.91 ± 1.501
7.092AlaLeu: 7.092 ± 0.811
0.546AlaMet: 0.546 ± 0.62
3.273AlaAsn: 3.273 ± 0.723
3.819AlaPro: 3.819 ± 2.198
2.182AlaGln: 2.182 ± 0.956
6.001AlaArg: 6.001 ± 2.292
4.364AlaSer: 4.364 ± 1.764
3.273AlaThr: 3.273 ± 1.308
3.819AlaVal: 3.819 ± 0.614
2.728AlaTrp: 2.728 ± 1.063
3.273AlaTyr: 3.273 ± 0.982
0.0AlaXaa: 0.0 ± 0.0
Cys
0.546CysAla: 0.546 ± 0.335
0.0CysCys: 0.0 ± 0.0
3.273CysAsp: 3.273 ± 1.499
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.546CysHis: 0.546 ± 0.335
1.091CysIle: 1.091 ± 0.67
1.637CysLys: 1.637 ± 0.595
1.637CysLeu: 1.637 ± 1.369
0.546CysMet: 0.546 ± 0.335
0.546CysAsn: 0.546 ± 0.335
3.273CysPro: 3.273 ± 1.263
0.546CysGln: 0.546 ± 0.335
1.091CysArg: 1.091 ± 0.67
1.091CysSer: 1.091 ± 0.67
0.0CysThr: 0.0 ± 0.0
0.546CysVal: 0.546 ± 0.895
0.0CysTrp: 0.0 ± 0.0
1.637CysTyr: 1.637 ± 0.973
0.0CysXaa: 0.0 ± 0.0
Asp
4.364AspAla: 4.364 ± 0.781
0.0AspCys: 0.0 ± 0.0
2.182AspAsp: 2.182 ± 0.827
3.273AspGlu: 3.273 ± 0.764
1.637AspPhe: 1.637 ± 0.616
3.273AspGly: 3.273 ± 1.493
1.091AspHis: 1.091 ± 0.5
1.637AspIle: 1.637 ± 0.616
6.547AspLys: 6.547 ± 1.306
0.546AspLeu: 0.546 ± 0.335
1.091AspMet: 1.091 ± 0.67
0.546AspAsn: 0.546 ± 0.335
3.273AspPro: 3.273 ± 1.134
4.364AspGln: 4.364 ± 1.628
3.273AspArg: 3.273 ± 2.167
3.819AspSer: 3.819 ± 1.486
2.728AspThr: 2.728 ± 0.829
0.546AspVal: 0.546 ± 0.895
0.0AspTrp: 0.0 ± 0.0
2.728AspTyr: 2.728 ± 1.047
0.0AspXaa: 0.0 ± 0.0
Glu
6.001GluAla: 6.001 ± 1.898
0.546GluCys: 0.546 ± 0.335
2.728GluAsp: 2.728 ± 1.517
4.91GluGlu: 4.91 ± 1.859
4.364GluPhe: 4.364 ± 1.165
2.182GluGly: 2.182 ± 0.827
1.091GluHis: 1.091 ± 0.67
4.91GluIle: 4.91 ± 0.906
3.273GluLys: 3.273 ± 1.306
4.91GluLeu: 4.91 ± 0.817
1.091GluMet: 1.091 ± 0.5
0.546GluAsn: 0.546 ± 0.787
2.728GluPro: 2.728 ± 1.003
4.364GluGln: 4.364 ± 1.628
3.273GluArg: 3.273 ± 1.439
4.364GluSer: 4.364 ± 1.15
1.637GluThr: 1.637 ± 0.82
6.001GluVal: 6.001 ± 1.831
2.182GluTrp: 2.182 ± 0.472
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.182PheAla: 2.182 ± 0.999
1.091PheCys: 1.091 ± 0.67
1.637PheAsp: 1.637 ± 1.005
1.637PheGlu: 1.637 ± 0.705
0.546PhePhe: 0.546 ± 0.335
1.637PheGly: 1.637 ± 0.799
1.091PheHis: 1.091 ± 0.5
3.819PheIle: 3.819 ± 1.528
2.728PheLys: 2.728 ± 1.269
2.728PheLeu: 2.728 ± 1.047
2.728PheMet: 2.728 ± 0.954
0.546PheAsn: 0.546 ± 0.787
0.546PhePro: 0.546 ± 0.895
0.546PheGln: 0.546 ± 0.335
1.637PheArg: 1.637 ± 0.595
2.728PheSer: 2.728 ± 2.437
1.091PheThr: 1.091 ± 0.5
3.273PheVal: 3.273 ± 1.499
0.0PheTrp: 0.0 ± 0.0
1.637PheTyr: 1.637 ± 0.705
0.0PheXaa: 0.0 ± 0.0
Gly
4.364GlyAla: 4.364 ± 4.572
1.091GlyCys: 1.091 ± 0.816
2.728GlyAsp: 2.728 ± 1.314
1.091GlyGlu: 1.091 ± 0.816
2.182GlyPhe: 2.182 ± 0.893
3.273GlyGly: 3.273 ± 0.576
1.091GlyHis: 1.091 ± 0.816
2.728GlyIle: 2.728 ± 1.112
7.638GlyLys: 7.638 ± 1.25
7.638GlyLeu: 7.638 ± 1.174
1.091GlyMet: 1.091 ± 0.67
2.182GlyAsn: 2.182 ± 0.893
2.182GlyPro: 2.182 ± 1.571
1.091GlyGln: 1.091 ± 0.65
2.182GlyArg: 2.182 ± 1.379
1.637GlySer: 1.637 ± 1.795
3.273GlyThr: 3.273 ± 0.576
4.364GlyVal: 4.364 ± 1.628
0.546GlyTrp: 0.546 ± 0.756
0.546GlyTyr: 0.546 ± 0.335
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.091HisCys: 1.091 ± 0.5
1.091HisAsp: 1.091 ± 0.5
0.546HisGlu: 0.546 ± 1.018
0.546HisPhe: 0.546 ± 0.335
1.637HisGly: 1.637 ± 0.595
2.728HisHis: 2.728 ± 2.064
1.637HisIle: 1.637 ± 0.869
1.091HisLys: 1.091 ± 0.67
2.728HisLeu: 2.728 ± 0.829
1.091HisMet: 1.091 ± 0.5
2.728HisAsn: 2.728 ± 0.81
2.728HisPro: 2.728 ± 1.269
2.182HisGln: 2.182 ± 0.956
1.091HisArg: 1.091 ± 1.2
2.182HisSer: 2.182 ± 1.034
1.091HisThr: 1.091 ± 0.5
0.546HisVal: 0.546 ± 0.335
1.637HisTrp: 1.637 ± 0.595
1.091HisTyr: 1.091 ± 0.5
0.0HisXaa: 0.0 ± 0.0
Ile
1.091IleAla: 1.091 ± 0.67
0.546IleCys: 0.546 ± 0.895
2.182IleAsp: 2.182 ± 0.472
5.456IleGlu: 5.456 ± 0.979
2.182IlePhe: 2.182 ± 0.827
0.546IleGly: 0.546 ± 0.335
3.819IleHis: 3.819 ± 1.049
2.728IleIle: 2.728 ± 1.592
2.728IleLys: 2.728 ± 1.112
4.91IleLeu: 4.91 ± 1.158
0.546IleMet: 0.546 ± 0.756
2.182IleAsn: 2.182 ± 0.75
4.364IlePro: 4.364 ± 0.932
2.182IleGln: 2.182 ± 1.564
2.728IleArg: 2.728 ± 0.81
7.638IleSer: 7.638 ± 1.552
5.456IleThr: 5.456 ± 1.098
4.364IleVal: 4.364 ± 1.291
0.546IleTrp: 0.546 ± 0.895
2.728IleTyr: 2.728 ± 1.314
0.0IleXaa: 0.0 ± 0.0
Lys
2.728LysAla: 2.728 ± 1.675
0.546LysCys: 0.546 ± 1.018
2.728LysAsp: 2.728 ± 1.126
5.456LysGlu: 5.456 ± 2.093
2.182LysPhe: 2.182 ± 0.827
2.182LysGly: 2.182 ± 0.893
3.819LysHis: 3.819 ± 1.528
2.182LysIle: 2.182 ± 0.472
1.091LysLys: 1.091 ± 0.67
6.547LysLeu: 6.547 ± 1.713
3.819LysMet: 3.819 ± 1.439
1.637LysAsn: 1.637 ± 0.595
4.364LysPro: 4.364 ± 0.932
1.637LysGln: 1.637 ± 1.028
3.273LysArg: 3.273 ± 0.764
4.364LysSer: 4.364 ± 2.284
3.819LysThr: 3.819 ± 1.738
2.182LysVal: 2.182 ± 0.999
2.182LysTrp: 2.182 ± 1.034
3.819LysTyr: 3.819 ± 1.359
0.546LysXaa: 0.546 ± 0.335
Leu
3.273LeuAla: 3.273 ± 1.42
1.091LeuCys: 1.091 ± 1.492
2.182LeuAsp: 2.182 ± 0.827
3.273LeuGlu: 3.273 ± 0.982
0.546LeuPhe: 0.546 ± 1.018
3.273LeuGly: 3.273 ± 1.439
1.637LeuHis: 1.637 ± 0.869
3.819LeuIle: 3.819 ± 1.159
4.91LeuLys: 4.91 ± 1.931
10.911LeuLeu: 10.911 ± 4.319
1.091LeuMet: 1.091 ± 0.5
1.637LeuAsn: 1.637 ± 0.799
5.456LeuPro: 5.456 ± 1.542
6.547LeuGln: 6.547 ± 1.884
7.638LeuArg: 7.638 ± 2.711
9.82LeuSer: 9.82 ± 1.561
4.91LeuThr: 4.91 ± 0.825
10.911LeuVal: 10.911 ± 2.4
1.637LeuTrp: 1.637 ± 1.679
1.637LeuTyr: 1.637 ± 0.595
0.0LeuXaa: 0.0 ± 0.0
Met
1.637MetAla: 1.637 ± 0.973
0.546MetCys: 0.546 ± 0.335
0.546MetAsp: 0.546 ± 0.756
3.819MetGlu: 3.819 ± 1.43
1.091MetPhe: 1.091 ± 0.5
2.728MetGly: 2.728 ± 1.111
0.0MetHis: 0.0 ± 0.0
0.546MetIle: 0.546 ± 0.335
1.091MetLys: 1.091 ± 0.67
2.728MetLeu: 2.728 ± 1.063
0.546MetMet: 0.546 ± 0.335
2.728MetAsn: 2.728 ± 0.539
0.546MetPro: 0.546 ± 0.335
0.0MetGln: 0.0 ± 0.0
1.637MetArg: 1.637 ± 0.595
3.273MetSer: 3.273 ± 0.717
0.0MetThr: 0.0 ± 0.0
1.091MetVal: 1.091 ± 0.67
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.091AsnAla: 1.091 ± 1.192
1.637AsnCys: 1.637 ± 0.595
0.546AsnAsp: 0.546 ± 0.335
1.091AsnGlu: 1.091 ± 0.5
1.091AsnPhe: 1.091 ± 1.574
2.182AsnGly: 2.182 ± 0.934
0.0AsnHis: 0.0 ± 0.0
2.182AsnIle: 2.182 ± 1.564
1.091AsnLys: 1.091 ± 0.67
2.728AsnLeu: 2.728 ± 0.539
0.0AsnMet: 0.0 ± 0.0
2.728AsnAsn: 2.728 ± 0.539
2.728AsnPro: 2.728 ± 1.047
1.091AsnGln: 1.091 ± 0.5
2.182AsnArg: 2.182 ± 0.956
2.182AsnSer: 2.182 ± 0.827
3.273AsnThr: 3.273 ± 1.138
2.182AsnVal: 2.182 ± 1.182
0.0AsnTrp: 0.0 ± 0.0
0.546AsnTyr: 0.546 ± 0.335
0.0AsnXaa: 0.0 ± 0.0
Pro
4.364ProAla: 4.364 ± 1.605
1.091ProCys: 1.091 ± 0.67
3.819ProAsp: 3.819 ± 1.401
7.638ProGlu: 7.638 ± 1.168
2.182ProPhe: 2.182 ± 0.827
1.091ProGly: 1.091 ± 0.65
1.637ProHis: 1.637 ± 0.616
4.91ProIle: 4.91 ± 2.328
6.001ProLys: 6.001 ± 1.142
3.273ProLeu: 3.273 ± 1.371
0.0ProMet: 0.0 ± 0.0
0.546ProAsn: 0.546 ± 0.335
1.091ProPro: 1.091 ± 1.789
2.728ProGln: 2.728 ± 1.687
4.364ProArg: 4.364 ± 1.691
9.274ProSer: 9.274 ± 3.332
5.456ProThr: 5.456 ± 2.442
1.637ProVal: 1.637 ± 1.005
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.364GlnAla: 4.364 ± 1.498
3.273GlnCys: 3.273 ± 1.191
1.637GlnAsp: 1.637 ± 0.846
2.728GlnGlu: 2.728 ± 0.715
0.0GlnPhe: 0.0 ± 0.0
1.637GlnGly: 1.637 ± 1.37
0.546GlnHis: 0.546 ± 0.335
2.728GlnIle: 2.728 ± 0.539
2.728GlnLys: 2.728 ± 1.165
4.91GlnLeu: 4.91 ± 1.264
1.091GlnMet: 1.091 ± 0.65
2.182GlnAsn: 2.182 ± 1.314
2.182GlnPro: 2.182 ± 0.893
0.0GlnGln: 0.0 ± 0.0
2.728GlnArg: 2.728 ± 1.338
2.182GlnSer: 2.182 ± 1.602
2.182GlnThr: 2.182 ± 0.999
2.182GlnVal: 2.182 ± 0.472
0.546GlnTrp: 0.546 ± 0.335
3.273GlnTyr: 3.273 ± 0.576
0.0GlnXaa: 0.0 ± 0.0
Arg
4.364ArgAla: 4.364 ± 2.68
0.546ArgCys: 0.546 ± 0.335
3.819ArgAsp: 3.819 ± 1.102
0.546ArgGlu: 0.546 ± 0.895
5.456ArgPhe: 5.456 ± 1.098
3.819ArgGly: 3.819 ± 1.953
3.819ArgHis: 3.819 ± 1.513
3.819ArgIle: 3.819 ± 0.875
2.182ArgLys: 2.182 ± 1.034
4.364ArgLeu: 4.364 ± 1.144
3.273ArgMet: 3.273 ± 1.038
2.182ArgAsn: 2.182 ± 1.3
4.364ArgPro: 4.364 ± 1.15
3.819ArgGln: 3.819 ± 0.875
4.91ArgArg: 4.91 ± 2.341
3.819ArgSer: 3.819 ± 1.617
2.182ArgThr: 2.182 ± 0.992
3.819ArgVal: 3.819 ± 1.993
1.637ArgTrp: 1.637 ± 0.616
4.364ArgTyr: 4.364 ± 1.654
0.0ArgXaa: 0.0 ± 0.0
Ser
7.092SerAla: 7.092 ± 1.509
1.637SerCys: 1.637 ± 0.616
3.819SerAsp: 3.819 ± 1.222
3.819SerGlu: 3.819 ± 0.764
2.182SerPhe: 2.182 ± 0.472
4.364SerGly: 4.364 ± 1.764
0.546SerHis: 0.546 ± 0.756
6.547SerIle: 6.547 ± 1.201
2.182SerLys: 2.182 ± 0.893
9.274SerLeu: 9.274 ± 1.44
0.546SerMet: 0.546 ± 0.895
1.091SerAsn: 1.091 ± 0.5
5.456SerPro: 5.456 ± 2.123
2.728SerGln: 2.728 ± 0.539
4.91SerArg: 4.91 ± 1.206
5.456SerSer: 5.456 ± 1.815
3.819SerThr: 3.819 ± 2.465
4.364SerVal: 4.364 ± 2.225
3.819SerTrp: 3.819 ± 1.505
4.364SerTyr: 4.364 ± 2.305
0.0SerXaa: 0.0 ± 0.0
Thr
4.91ThrAla: 4.91 ± 2.004
1.091ThrCys: 1.091 ± 0.5
3.819ThrAsp: 3.819 ± 0.69
3.819ThrGlu: 3.819 ± 1.536
1.637ThrPhe: 1.637 ± 0.595
6.001ThrGly: 6.001 ± 1.122
2.182ThrHis: 2.182 ± 0.999
1.091ThrIle: 1.091 ± 0.719
1.091ThrLys: 1.091 ± 0.5
1.091ThrLeu: 1.091 ± 0.67
3.819ThrMet: 3.819 ± 1.528
0.0ThrAsn: 0.0 ± 0.0
7.092ThrPro: 7.092 ± 1.968
2.182ThrGln: 2.182 ± 0.75
4.91ThrArg: 4.91 ± 0.573
1.091ThrSer: 1.091 ± 0.65
7.092ThrThr: 7.092 ± 2.626
2.728ThrVal: 2.728 ± 0.813
0.0ThrTrp: 0.0 ± 0.0
1.091ThrTyr: 1.091 ± 0.965
0.0ThrXaa: 0.0 ± 0.0
Val
6.547ValAla: 6.547 ± 1.405
0.546ValCys: 0.546 ± 0.335
2.182ValAsp: 2.182 ± 0.827
6.001ValGlu: 6.001 ± 1.773
2.182ValPhe: 2.182 ± 0.827
5.456ValGly: 5.456 ± 2.78
1.637ValHis: 1.637 ± 0.846
4.364ValIle: 4.364 ± 0.945
4.91ValLys: 4.91 ± 1.398
3.273ValLeu: 3.273 ± 2.108
0.546ValMet: 0.546 ± 0.335
1.091ValAsn: 1.091 ± 0.5
3.273ValPro: 3.273 ± 2.327
1.091ValGln: 1.091 ± 0.65
5.456ValArg: 5.456 ± 2.093
5.456ValSer: 5.456 ± 1.815
2.728ValThr: 2.728 ± 1.111
2.728ValVal: 2.728 ± 1.442
1.091ValTrp: 1.091 ± 0.5
1.637ValTyr: 1.637 ± 0.595
0.0ValXaa: 0.0 ± 0.0
Trp
3.273TrpAla: 3.273 ± 1.692
0.546TrpCys: 0.546 ± 0.335
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.637TrpPhe: 1.637 ± 0.846
1.091TrpGly: 1.091 ± 0.816
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.637TrpLeu: 1.637 ± 0.595
0.546TrpMet: 0.546 ± 0.335
1.091TrpAsn: 1.091 ± 1.492
1.091TrpPro: 1.091 ± 0.5
1.637TrpGln: 1.637 ± 0.705
1.637TrpArg: 1.637 ± 0.616
0.546TrpSer: 0.546 ± 0.335
0.0TrpThr: 0.0 ± 0.0
2.728TrpVal: 2.728 ± 0.829
1.091TrpTrp: 1.091 ± 0.5
1.091TrpTyr: 1.091 ± 0.5
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.637TyrAla: 1.637 ± 0.595
0.546TyrCys: 0.546 ± 1.018
2.728TyrAsp: 2.728 ± 1.047
2.182TyrGlu: 2.182 ± 0.827
0.546TyrPhe: 0.546 ± 0.895
2.182TyrGly: 2.182 ± 0.827
1.091TyrHis: 1.091 ± 0.965
4.364TyrIle: 4.364 ± 1.628
3.273TyrLys: 3.273 ± 0.982
3.273TyrLeu: 3.273 ± 1.42
0.0TyrMet: 0.0 ± 0.0
1.091TyrAsn: 1.091 ± 0.965
0.546TyrPro: 0.546 ± 0.756
2.182TyrGln: 2.182 ± 1.571
2.182TyrArg: 2.182 ± 0.472
2.728TyrSer: 2.728 ± 0.962
2.728TyrThr: 2.728 ± 1.112
2.182TyrVal: 2.182 ± 1.3
0.0TyrTrp: 0.0 ± 0.0
1.637TyrTyr: 1.637 ± 1.005
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.546XaaGly: 0.546 ± 0.335
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1834 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski