Amino acid dipepetide frequency for Tortoise microvirus 28

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.547AlaAla: 7.547 ± 2.634
0.755AlaCys: 0.755 ± 0.484
6.038AlaAsp: 6.038 ± 2.505
3.774AlaGlu: 3.774 ± 1.279
1.509AlaPhe: 1.509 ± 0.603
6.792AlaGly: 6.792 ± 1.663
3.774AlaHis: 3.774 ± 0.706
2.264AlaIle: 2.264 ± 1.006
2.264AlaLys: 2.264 ± 2.39
4.528AlaLeu: 4.528 ± 0.783
0.755AlaMet: 0.755 ± 1.027
1.509AlaAsn: 1.509 ± 0.713
3.774AlaPro: 3.774 ± 1.713
4.528AlaGln: 4.528 ± 2.756
6.038AlaArg: 6.038 ± 0.788
4.528AlaSer: 4.528 ± 2.888
3.774AlaThr: 3.774 ± 1.466
4.528AlaVal: 4.528 ± 1.129
0.755AlaTrp: 0.755 ± 0.484
1.509AlaTyr: 1.509 ± 0.713
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.264CysGlu: 2.264 ± 0.935
0.755CysPhe: 0.755 ± 0.667
2.264CysGly: 2.264 ± 0.867
0.0CysHis: 0.0 ± 0.0
1.509CysIle: 1.509 ± 0.603
0.755CysLys: 0.755 ± 0.667
2.264CysLeu: 2.264 ± 2.001
0.0CysMet: 0.0 ± 0.0
0.755CysAsn: 0.755 ± 0.944
0.755CysPro: 0.755 ± 0.667
0.755CysGln: 0.755 ± 0.484
2.264CysArg: 2.264 ± 2.001
2.264CysSer: 2.264 ± 1.658
0.755CysThr: 0.755 ± 0.484
0.755CysVal: 0.755 ± 0.944
0.755CysTrp: 0.755 ± 0.667
0.755CysTyr: 0.755 ± 0.667
0.0CysXaa: 0.0 ± 0.0
Asp
1.509AspAla: 1.509 ± 0.954
0.755AspCys: 0.755 ± 0.667
4.528AspAsp: 4.528 ± 2.482
3.774AspGlu: 3.774 ± 1.318
4.528AspPhe: 4.528 ± 0.693
4.528AspGly: 4.528 ± 1.428
1.509AspHis: 1.509 ± 0.603
3.774AspIle: 3.774 ± 2.504
0.755AspLys: 0.755 ± 0.944
5.283AspLeu: 5.283 ± 0.988
4.528AspMet: 4.528 ± 1.733
0.755AspAsn: 0.755 ± 0.484
2.264AspPro: 2.264 ± 1.11
1.509AspGln: 1.509 ± 1.253
1.509AspArg: 1.509 ± 0.603
0.755AspSer: 0.755 ± 0.667
1.509AspThr: 1.509 ± 0.713
1.509AspVal: 1.509 ± 1.16
1.509AspTrp: 1.509 ± 1.334
3.774AspTyr: 3.774 ± 1.259
0.0AspXaa: 0.0 ± 0.0
Glu
6.792GluAla: 6.792 ± 6.139
0.755GluCys: 0.755 ± 0.667
0.755GluAsp: 0.755 ± 1.027
3.019GluGlu: 3.019 ± 1.876
3.019GluPhe: 3.019 ± 2.113
0.755GluGly: 0.755 ± 0.484
5.283GluHis: 5.283 ± 2.567
4.528GluIle: 4.528 ± 1.843
3.019GluLys: 3.019 ± 0.958
6.792GluLeu: 6.792 ± 3.217
2.264GluMet: 2.264 ± 2.187
3.019GluAsn: 3.019 ± 1.934
3.774GluPro: 3.774 ± 1.366
3.019GluGln: 3.019 ± 0.542
3.774GluArg: 3.774 ± 1.882
3.774GluSer: 3.774 ± 1.916
3.019GluThr: 3.019 ± 1.098
3.774GluVal: 3.774 ± 1.777
2.264GluTrp: 2.264 ± 1.665
3.019GluTyr: 3.019 ± 0.922
0.0GluXaa: 0.0 ± 0.0
Phe
2.264PheAla: 2.264 ± 1.451
0.0PheCys: 0.0 ± 0.0
4.528PheAsp: 4.528 ± 2.103
1.509PheGlu: 1.509 ± 0.842
3.774PhePhe: 3.774 ± 1.413
3.774PheGly: 3.774 ± 1.747
0.755PheHis: 0.755 ± 0.667
2.264PheIle: 2.264 ± 1.177
2.264PheLys: 2.264 ± 1.293
5.283PheLeu: 5.283 ± 1.77
1.509PheMet: 1.509 ± 1.221
3.019PheAsn: 3.019 ± 1.934
1.509PhePro: 1.509 ± 0.967
2.264PheGln: 2.264 ± 1.451
1.509PheArg: 1.509 ± 1.253
1.509PheSer: 1.509 ± 1.334
3.774PheThr: 3.774 ± 1.711
2.264PheVal: 2.264 ± 0.867
0.0PheTrp: 0.0 ± 0.0
3.019PheTyr: 3.019 ± 1.815
0.0PheXaa: 0.0 ± 0.0
Gly
6.038GlyAla: 6.038 ± 1.496
3.019GlyCys: 3.019 ± 2.668
1.509GlyAsp: 1.509 ± 0.832
7.547GlyGlu: 7.547 ± 2.798
3.019GlyPhe: 3.019 ± 1.207
3.774GlyGly: 3.774 ± 0.646
3.019GlyHis: 3.019 ± 0.542
5.283GlyIle: 5.283 ± 1.094
1.509GlyLys: 1.509 ± 1.334
6.038GlyLeu: 6.038 ± 1.659
0.755GlyMet: 0.755 ± 0.484
3.019GlyAsn: 3.019 ± 1.304
0.0GlyPro: 0.0 ± 0.0
3.019GlyGln: 3.019 ± 1.934
6.038GlyArg: 6.038 ± 2.388
4.528GlySer: 4.528 ± 1.486
2.264GlyThr: 2.264 ± 1.451
3.019GlyVal: 3.019 ± 0.542
0.0GlyTrp: 0.0 ± 0.0
4.528GlyTyr: 4.528 ± 0.825
0.0GlyXaa: 0.0 ± 0.0
His
0.755HisAla: 0.755 ± 0.944
1.509HisCys: 1.509 ± 0.603
1.509HisAsp: 1.509 ± 0.832
3.774HisGlu: 3.774 ± 1.443
1.509HisPhe: 1.509 ± 0.603
2.264HisGly: 2.264 ± 0.921
0.0HisHis: 0.0 ± 0.0
0.755HisIle: 0.755 ± 0.797
1.509HisLys: 1.509 ± 0.842
2.264HisLeu: 2.264 ± 0.517
0.0HisMet: 0.0 ± 0.0
1.509HisAsn: 1.509 ± 0.603
2.264HisPro: 2.264 ± 0.921
0.755HisGln: 0.755 ± 0.484
2.264HisArg: 2.264 ± 0.921
0.755HisSer: 0.755 ± 0.944
0.0HisThr: 0.0 ± 0.0
1.509HisVal: 1.509 ± 1.177
0.755HisTrp: 0.755 ± 0.484
2.264HisTyr: 2.264 ± 1.11
0.0HisXaa: 0.0 ± 0.0
Ile
2.264IleAla: 2.264 ± 1.451
0.0IleCys: 0.0 ± 0.0
2.264IleAsp: 2.264 ± 1.115
2.264IleGlu: 2.264 ± 1.432
1.509IlePhe: 1.509 ± 0.603
6.038IleGly: 6.038 ± 2.81
0.755IleHis: 0.755 ± 0.944
2.264IleIle: 2.264 ± 0.867
2.264IleLys: 2.264 ± 0.867
4.528IleLeu: 4.528 ± 2.21
3.019IleMet: 3.019 ± 0.615
0.755IleAsn: 0.755 ± 0.484
4.528IlePro: 4.528 ± 1.637
0.755IleGln: 0.755 ± 0.797
3.019IleArg: 3.019 ± 1.207
3.774IleSer: 3.774 ± 1.466
3.019IleThr: 3.019 ± 0.911
2.264IleVal: 2.264 ± 0.981
0.755IleTrp: 0.755 ± 0.484
3.019IleTyr: 3.019 ± 0.907
0.0IleXaa: 0.0 ± 0.0
Lys
2.264LysAla: 2.264 ± 1.177
2.264LysCys: 2.264 ± 0.935
3.774LysAsp: 3.774 ± 2.469
1.509LysGlu: 1.509 ± 0.842
3.019LysPhe: 3.019 ± 1.207
2.264LysGly: 2.264 ± 1.292
1.509LysHis: 1.509 ± 0.713
3.774LysIle: 3.774 ± 2.866
6.038LysLys: 6.038 ± 5.336
1.509LysLeu: 1.509 ± 0.842
1.509LysMet: 1.509 ± 1.334
1.509LysAsn: 1.509 ± 0.842
1.509LysPro: 1.509 ± 0.603
0.755LysGln: 0.755 ± 0.667
4.528LysArg: 4.528 ± 2.526
2.264LysSer: 2.264 ± 1.293
0.755LysThr: 0.755 ± 0.667
3.019LysVal: 3.019 ± 2.113
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
3.774LeuAla: 3.774 ± 1.139
0.755LeuCys: 0.755 ± 0.484
5.283LeuAsp: 5.283 ± 2.2
5.283LeuGlu: 5.283 ± 3.193
3.774LeuPhe: 3.774 ± 1.977
3.774LeuGly: 3.774 ± 2.117
1.509LeuHis: 1.509 ± 0.842
1.509LeuIle: 1.509 ± 0.713
4.528LeuLys: 4.528 ± 2.335
6.792LeuLeu: 6.792 ± 1.663
0.755LeuMet: 0.755 ± 1.027
5.283LeuAsn: 5.283 ± 0.943
5.283LeuPro: 5.283 ± 2.049
4.528LeuGln: 4.528 ± 1.522
6.038LeuArg: 6.038 ± 1.915
6.792LeuSer: 6.792 ± 1.977
3.774LeuThr: 3.774 ± 1.311
3.774LeuVal: 3.774 ± 2.418
0.755LeuTrp: 0.755 ± 0.484
3.019LeuTyr: 3.019 ± 1.267
0.0LeuXaa: 0.0 ± 0.0
Met
3.019MetAla: 3.019 ± 1.684
0.755MetCys: 0.755 ± 0.667
1.509MetAsp: 1.509 ± 0.954
2.264MetGlu: 2.264 ± 1.115
0.0MetPhe: 0.0 ± 0.0
2.264MetGly: 2.264 ± 0.867
0.755MetHis: 0.755 ± 0.484
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.264MetLeu: 2.264 ± 1.302
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.774MetPro: 3.774 ± 0.888
0.755MetGln: 0.755 ± 0.484
5.283MetArg: 5.283 ± 1.963
2.264MetSer: 2.264 ± 0.867
0.0MetThr: 0.0 ± 0.0
2.264MetVal: 2.264 ± 0.921
0.0MetTrp: 0.0 ± 0.0
2.264MetTyr: 2.264 ± 1.59
0.0MetXaa: 0.0 ± 0.0
Asn
1.509AsnAla: 1.509 ± 1.322
0.755AsnCys: 0.755 ± 0.944
0.755AsnAsp: 0.755 ± 0.667
2.264AsnGlu: 2.264 ± 1.451
3.019AsnPhe: 3.019 ± 1.207
4.528AsnGly: 4.528 ± 1.798
0.0AsnHis: 0.0 ± 0.0
3.774AsnIle: 3.774 ± 1.713
0.0AsnLys: 0.0 ± 0.0
3.774AsnLeu: 3.774 ± 1.711
1.509AsnMet: 1.509 ± 0.713
0.755AsnAsn: 0.755 ± 0.484
2.264AsnPro: 2.264 ± 1.451
2.264AsnGln: 2.264 ± 1.432
2.264AsnArg: 2.264 ± 1.451
3.019AsnSer: 3.019 ± 1.934
2.264AsnThr: 2.264 ± 1.11
3.774AsnVal: 3.774 ± 1.575
0.755AsnTrp: 0.755 ± 0.797
2.264AsnTyr: 2.264 ± 1.432
0.0AsnXaa: 0.0 ± 0.0
Pro
3.774ProAla: 3.774 ± 2.418
0.755ProCys: 0.755 ± 1.027
2.264ProAsp: 2.264 ± 0.867
3.774ProGlu: 3.774 ± 0.706
2.264ProPhe: 2.264 ± 0.867
5.283ProGly: 5.283 ± 1.931
0.755ProHis: 0.755 ± 0.667
3.774ProIle: 3.774 ± 1.139
3.019ProLys: 3.019 ± 0.922
3.774ProLeu: 3.774 ± 1.704
2.264ProMet: 2.264 ± 0.921
2.264ProAsn: 2.264 ± 1.451
2.264ProPro: 2.264 ± 0.981
3.019ProGln: 3.019 ± 1.304
6.792ProArg: 6.792 ± 2.102
3.019ProSer: 3.019 ± 1.267
4.528ProThr: 4.528 ± 1.739
3.019ProVal: 3.019 ± 1.934
0.755ProTrp: 0.755 ± 0.484
2.264ProTyr: 2.264 ± 1.006
0.0ProXaa: 0.0 ± 0.0
Gln
3.774GlnAla: 3.774 ± 1.052
1.509GlnCys: 1.509 ± 0.603
3.019GlnAsp: 3.019 ± 1.207
2.264GlnGlu: 2.264 ± 1.115
3.774GlnPhe: 3.774 ± 2.117
2.264GlnGly: 2.264 ± 0.517
1.509GlnHis: 1.509 ± 0.713
1.509GlnIle: 1.509 ± 1.253
2.264GlnLys: 2.264 ± 1.712
0.755GlnLeu: 0.755 ± 0.797
1.509GlnMet: 1.509 ± 1.593
2.264GlnAsn: 2.264 ± 1.451
0.755GlnPro: 0.755 ± 0.484
3.774GlnGln: 3.774 ± 2.336
3.774GlnArg: 3.774 ± 2.117
1.509GlnSer: 1.509 ± 0.603
4.528GlnThr: 4.528 ± 2.163
3.019GlnVal: 3.019 ± 1.423
0.755GlnTrp: 0.755 ± 0.484
2.264GlnTyr: 2.264 ± 1.451
0.0GlnXaa: 0.0 ± 0.0
Arg
5.283ArgAla: 5.283 ± 2.186
0.755ArgCys: 0.755 ± 0.667
1.509ArgAsp: 1.509 ± 0.967
4.528ArgGlu: 4.528 ± 2.888
3.019ArgPhe: 3.019 ± 0.907
3.019ArgGly: 3.019 ± 0.911
1.509ArgHis: 1.509 ± 0.954
1.509ArgIle: 1.509 ± 1.253
7.547ArgLys: 7.547 ± 5.783
9.057ArgLeu: 9.057 ± 1.263
2.264ArgMet: 2.264 ± 1.29
6.038ArgAsn: 6.038 ± 1.504
3.774ArgPro: 3.774 ± 1.711
9.811ArgGln: 9.811 ± 3.782
9.057ArgArg: 9.057 ± 1.864
3.774ArgSer: 3.774 ± 0.888
3.019ArgThr: 3.019 ± 1.207
3.774ArgVal: 3.774 ± 1.311
0.0ArgTrp: 0.0 ± 0.0
3.774ArgTyr: 3.774 ± 0.888
0.0ArgXaa: 0.0 ± 0.0
Ser
3.774SerAla: 3.774 ± 3.019
0.755SerCys: 0.755 ± 0.667
5.283SerAsp: 5.283 ± 1.74
8.302SerGlu: 8.302 ± 3.93
1.509SerPhe: 1.509 ± 0.967
5.283SerGly: 5.283 ± 1.206
1.509SerHis: 1.509 ± 0.967
3.774SerIle: 3.774 ± 1.413
0.755SerLys: 0.755 ± 0.667
5.283SerLeu: 5.283 ± 1.357
1.509SerMet: 1.509 ± 0.967
0.755SerAsn: 0.755 ± 0.484
5.283SerPro: 5.283 ± 1.934
1.509SerGln: 1.509 ± 0.713
3.774SerArg: 3.774 ± 0.793
3.774SerSer: 3.774 ± 1.366
3.019SerThr: 3.019 ± 0.96
3.774SerVal: 3.774 ± 1.279
0.755SerTrp: 0.755 ± 0.484
1.509SerTyr: 1.509 ± 0.967
0.0SerXaa: 0.0 ± 0.0
Thr
5.283ThrAla: 5.283 ± 1.136
1.509ThrCys: 1.509 ± 0.832
1.509ThrAsp: 1.509 ± 0.713
3.019ThrGlu: 3.019 ± 2.021
0.755ThrPhe: 0.755 ± 0.484
2.264ThrGly: 2.264 ± 0.942
1.509ThrHis: 1.509 ± 0.967
0.755ThrIle: 0.755 ± 0.944
0.0ThrLys: 0.0 ± 0.0
0.755ThrLeu: 0.755 ± 0.667
0.0ThrMet: 0.0 ± 0.0
2.264ThrAsn: 2.264 ± 1.432
7.547ThrPro: 7.547 ± 3.222
2.264ThrGln: 2.264 ± 1.451
5.283ThrArg: 5.283 ± 1.136
6.038ThrSer: 6.038 ± 2.575
2.264ThrThr: 2.264 ± 1.451
0.755ThrVal: 0.755 ± 0.484
0.755ThrTrp: 0.755 ± 0.484
3.019ThrTyr: 3.019 ± 1.325
0.0ThrXaa: 0.0 ± 0.0
Val
7.547ValAla: 7.547 ± 3.516
1.509ValCys: 1.509 ± 1.177
3.019ValAsp: 3.019 ± 1.664
3.019ValGlu: 3.019 ± 0.96
2.264ValPhe: 2.264 ± 1.177
3.019ValGly: 3.019 ± 1.816
0.0ValHis: 0.0 ± 0.0
3.019ValIle: 3.019 ± 1.207
0.755ValLys: 0.755 ± 0.484
3.774ValLeu: 3.774 ± 0.793
2.264ValMet: 2.264 ± 1.352
3.019ValAsn: 3.019 ± 1.2
4.528ValPro: 4.528 ± 2.901
0.755ValGln: 0.755 ± 0.484
3.019ValArg: 3.019 ± 1.267
3.774ValSer: 3.774 ± 1.713
1.509ValThr: 1.509 ± 0.954
3.774ValVal: 3.774 ± 1.711
0.0ValTrp: 0.0 ± 0.0
0.755ValTyr: 0.755 ± 0.484
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.755TrpCys: 0.755 ± 0.667
0.755TrpAsp: 0.755 ± 0.484
1.509TrpGlu: 1.509 ± 0.967
0.0TrpPhe: 0.0 ± 0.0
0.755TrpGly: 0.755 ± 0.667
0.755TrpHis: 0.755 ± 0.484
0.755TrpIle: 0.755 ± 0.944
0.755TrpLys: 0.755 ± 0.667
2.264TrpLeu: 2.264 ± 0.921
0.0TrpMet: 0.0 ± 0.0
0.755TrpAsn: 0.755 ± 0.484
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.755TrpArg: 0.755 ± 0.484
1.509TrpSer: 1.509 ± 0.603
0.755TrpThr: 0.755 ± 0.484
0.755TrpVal: 0.755 ± 0.667
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.774TyrAla: 3.774 ± 1.311
0.755TyrCys: 0.755 ± 0.667
0.755TyrAsp: 0.755 ± 0.484
0.755TyrGlu: 0.755 ± 0.667
4.528TyrPhe: 4.528 ± 2.901
3.019TyrGly: 3.019 ± 1.876
1.509TyrHis: 1.509 ± 1.177
2.264TyrIle: 2.264 ± 0.867
3.774TyrLys: 3.774 ± 2.504
0.0TyrLeu: 0.0 ± 0.0
2.264TyrMet: 2.264 ± 0.517
2.264TyrAsn: 2.264 ± 0.921
3.774TyrPro: 3.774 ± 1.318
0.755TyrGln: 0.755 ± 0.484
6.038TyrArg: 6.038 ± 1.504
2.264TyrSer: 2.264 ± 0.921
3.019TyrThr: 3.019 ± 1.395
0.0TyrVal: 0.0 ± 0.0
1.509TyrTrp: 1.509 ± 0.967
3.019TyrTyr: 3.019 ± 1.815
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1326 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski