Amino acid dipepetide frequency for Tortoise microvirus 48

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
1.806AlaCys: 1.806 ± 1.734
5.418AlaAsp: 5.418 ± 2.372
1.806AlaGlu: 1.806 ± 0.505
1.806AlaPhe: 1.806 ± 0.689
3.612AlaGly: 3.612 ± 1.372
0.0AlaHis: 0.0 ± 0.0
3.01AlaIle: 3.01 ± 1.278
3.612AlaLys: 3.612 ± 1.458
6.623AlaLeu: 6.623 ± 2.308
1.204AlaMet: 1.204 ± 0.742
4.816AlaAsn: 4.816 ± 0.918
5.418AlaPro: 5.418 ± 2.293
4.214AlaGln: 4.214 ± 1.988
6.02AlaArg: 6.02 ± 2.211
7.827AlaSer: 7.827 ± 3.585
1.806AlaThr: 1.806 ± 0.836
0.602AlaVal: 0.602 ± 0.426
1.204AlaTrp: 1.204 ± 1.167
4.214AlaTyr: 4.214 ± 1.81
0.0AlaXaa: 0.0 ± 0.0
Cys
1.204CysAla: 1.204 ± 0.472
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.204CysGly: 1.204 ± 0.871
0.0CysHis: 0.0 ± 0.0
2.408CysIle: 2.408 ± 1.715
0.0CysLys: 0.0 ± 0.0
1.204CysLeu: 1.204 ± 0.654
0.0CysMet: 0.0 ± 0.0
1.806CysAsn: 1.806 ± 1.118
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.204CysArg: 1.204 ± 1.156
1.204CysSer: 1.204 ± 1.156
0.602CysThr: 0.602 ± 0.426
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.816AspAla: 4.816 ± 1.587
0.602AspCys: 0.602 ± 0.669
3.612AspAsp: 3.612 ± 1.486
1.204AspGlu: 1.204 ± 0.942
4.816AspPhe: 4.816 ± 1.494
0.602AspGly: 0.602 ± 0.669
0.602AspHis: 0.602 ± 0.426
6.623AspIle: 6.623 ± 1.743
3.01AspLys: 3.01 ± 1.305
6.02AspLeu: 6.02 ± 1.377
3.01AspMet: 3.01 ± 1.287
6.02AspAsn: 6.02 ± 0.602
1.806AspPro: 1.806 ± 1.581
1.204AspGln: 1.204 ± 0.581
3.01AspArg: 3.01 ± 1.568
5.418AspSer: 5.418 ± 2.441
3.612AspThr: 3.612 ± 1.305
3.01AspVal: 3.01 ± 1.043
0.602AspTrp: 0.602 ± 0.578
4.214AspTyr: 4.214 ± 1.046
0.0AspXaa: 0.0 ± 0.0
Glu
1.204GluAla: 1.204 ± 0.942
0.602GluCys: 0.602 ± 0.793
3.01GluAsp: 3.01 ± 0.931
2.408GluGlu: 2.408 ± 0.897
2.408GluPhe: 2.408 ± 1.215
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
0.602GluIle: 0.602 ± 0.584
1.806GluLys: 1.806 ± 0.505
3.612GluLeu: 3.612 ± 1.375
1.806GluMet: 1.806 ± 1.58
1.204GluAsn: 1.204 ± 0.742
3.01GluPro: 3.01 ± 1.598
1.806GluGln: 1.806 ± 1.084
3.01GluArg: 3.01 ± 1.206
4.816GluSer: 4.816 ± 0.662
3.01GluThr: 3.01 ± 0.991
2.408GluVal: 2.408 ± 1.473
0.602GluTrp: 0.602 ± 0.578
3.612GluTyr: 3.612 ± 1.526
0.0GluXaa: 0.0 ± 0.0
Phe
2.408PheAla: 2.408 ± 0.568
1.204PheCys: 1.204 ± 0.654
2.408PheAsp: 2.408 ± 0.568
3.612PheGlu: 3.612 ± 1.424
4.214PhePhe: 4.214 ± 1.842
6.02PheGly: 6.02 ± 2.093
0.602PheHis: 0.602 ± 0.793
4.214PheIle: 4.214 ± 2.065
1.806PheLys: 1.806 ± 1.074
3.01PheLeu: 3.01 ± 1.064
3.612PheMet: 3.612 ± 1.559
1.806PheAsn: 1.806 ± 0.716
1.806PhePro: 1.806 ± 0.905
1.204PheGln: 1.204 ± 0.654
2.408PheArg: 2.408 ± 0.778
6.02PheSer: 6.02 ± 2.876
3.612PheThr: 3.612 ± 1.846
2.408PheVal: 2.408 ± 0.856
0.602PheTrp: 0.602 ± 0.426
1.806PheTyr: 1.806 ± 1.488
0.0PheXaa: 0.0 ± 0.0
Gly
5.418GlyAla: 5.418 ± 2.667
0.0GlyCys: 0.0 ± 0.0
1.806GlyAsp: 1.806 ± 1.367
0.602GlyGlu: 0.602 ± 0.578
4.214GlyPhe: 4.214 ± 1.422
6.623GlyGly: 6.623 ± 1.33
1.204GlyHis: 1.204 ± 0.472
3.612GlyIle: 3.612 ± 1.205
1.806GlyLys: 1.806 ± 0.905
7.225GlyLeu: 7.225 ± 1.578
0.0GlyMet: 0.0 ± 0.0
1.806GlyAsn: 1.806 ± 0.836
0.602GlyPro: 0.602 ± 0.426
1.204GlyGln: 1.204 ± 0.472
3.01GlyArg: 3.01 ± 1.447
10.837GlySer: 10.837 ± 1.941
4.214GlyThr: 4.214 ± 2.261
4.816GlyVal: 4.816 ± 2.201
0.602GlyTrp: 0.602 ± 0.426
3.612GlyTyr: 3.612 ± 0.942
0.0GlyXaa: 0.0 ± 0.0
His
0.602HisAla: 0.602 ± 0.426
0.0HisCys: 0.0 ± 0.0
1.806HisAsp: 1.806 ± 0.983
0.0HisGlu: 0.0 ± 0.0
2.408HisPhe: 2.408 ± 1.715
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.204HisAsn: 1.204 ± 0.472
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.408HisArg: 2.408 ± 1.646
0.602HisSer: 0.602 ± 0.669
1.204HisThr: 1.204 ± 0.654
1.806HisVal: 1.806 ± 1.241
1.806HisTrp: 1.806 ± 1.278
1.204HisTyr: 1.204 ± 0.472
0.0HisXaa: 0.0 ± 0.0
Ile
4.816IleAla: 4.816 ± 1.266
1.204IleCys: 1.204 ± 0.943
3.612IleAsp: 3.612 ± 1.13
3.01IleGlu: 3.01 ± 1.986
3.612IlePhe: 3.612 ± 1.578
5.418IleGly: 5.418 ± 1.481
0.602IleHis: 0.602 ± 0.669
9.633IleIle: 9.633 ± 7.152
0.602IleLys: 0.602 ± 0.578
3.612IleLeu: 3.612 ± 3.299
1.204IleMet: 1.204 ± 0.656
3.01IleAsn: 3.01 ± 1.074
1.806IlePro: 1.806 ± 0.689
5.418IleGln: 5.418 ± 1.779
4.816IleArg: 4.816 ± 1.704
4.816IleSer: 4.816 ± 0.662
4.214IleThr: 4.214 ± 1.514
3.01IleVal: 3.01 ± 1.581
0.0IleTrp: 0.0 ± 0.0
1.806IleTyr: 1.806 ± 0.772
0.0IleXaa: 0.0 ± 0.0
Lys
6.623LysAla: 6.623 ± 2.619
0.0LysCys: 0.0 ± 0.0
2.408LysAsp: 2.408 ± 1.631
1.806LysGlu: 1.806 ± 0.746
3.01LysPhe: 3.01 ± 1.447
0.602LysGly: 0.602 ± 0.426
1.204LysHis: 1.204 ± 0.654
3.612LysIle: 3.612 ± 1.065
1.806LysLys: 1.806 ± 0.746
3.612LysLeu: 3.612 ± 0.601
0.602LysMet: 0.602 ± 0.529
1.806LysAsn: 1.806 ± 1.195
1.204LysPro: 1.204 ± 0.852
2.408LysGln: 2.408 ± 1.162
3.612LysArg: 3.612 ± 2.11
3.01LysSer: 3.01 ± 1.589
3.612LysThr: 3.612 ± 2.186
4.214LysVal: 4.214 ± 0.732
0.0LysTrp: 0.0 ± 0.0
1.806LysTyr: 1.806 ± 1.195
0.0LysXaa: 0.0 ± 0.0
Leu
3.612LeuAla: 3.612 ± 1.287
0.602LeuCys: 0.602 ± 0.664
6.02LeuAsp: 6.02 ± 1.792
4.214LeuGlu: 4.214 ± 0.846
6.02LeuPhe: 6.02 ± 2.739
6.623LeuGly: 6.623 ± 2.582
1.204LeuHis: 1.204 ± 0.908
4.816LeuIle: 4.816 ± 1.24
7.827LeuLys: 7.827 ± 0.956
5.418LeuLeu: 5.418 ± 2.867
3.612LeuMet: 3.612 ± 1.066
3.612LeuAsn: 3.612 ± 1.218
5.418LeuPro: 5.418 ± 2.502
1.806LeuGln: 1.806 ± 0.902
6.623LeuArg: 6.623 ± 2.103
11.439LeuSer: 11.439 ± 3.633
5.418LeuThr: 5.418 ± 1.243
2.408LeuVal: 2.408 ± 0.75
0.602LeuTrp: 0.602 ± 0.426
4.214LeuTyr: 4.214 ± 2.007
0.0LeuXaa: 0.0 ± 0.0
Met
3.612MetAla: 3.612 ± 1.048
0.602MetCys: 0.602 ± 0.578
3.612MetAsp: 3.612 ± 1.073
0.602MetGlu: 0.602 ± 0.669
1.204MetPhe: 1.204 ± 0.654
0.602MetGly: 0.602 ± 0.584
0.0MetHis: 0.0 ± 0.0
0.602MetIle: 0.602 ± 0.426
2.408MetLys: 2.408 ± 1.892
4.214MetLeu: 4.214 ± 2.303
0.0MetMet: 0.0 ± 0.0
1.204MetAsn: 1.204 ± 0.581
0.0MetPro: 0.0 ± 0.0
0.602MetGln: 0.602 ± 0.578
1.204MetArg: 1.204 ± 0.742
1.204MetSer: 1.204 ± 0.742
0.602MetThr: 0.602 ± 0.426
0.602MetVal: 0.602 ± 0.426
0.0MetTrp: 0.0 ± 0.0
1.204MetTyr: 1.204 ± 1.019
0.0MetXaa: 0.0 ± 0.0
Asn
3.612AsnAla: 3.612 ± 1.436
1.204AsnCys: 1.204 ± 0.472
3.01AsnAsp: 3.01 ± 0.547
1.204AsnGlu: 1.204 ± 0.581
1.806AsnPhe: 1.806 ± 0.505
4.816AsnGly: 4.816 ± 1.473
0.602AsnHis: 0.602 ± 0.727
3.612AsnIle: 3.612 ± 1.551
2.408AsnLys: 2.408 ± 0.984
7.827AsnLeu: 7.827 ± 3.148
0.0AsnMet: 0.0 ± 0.0
2.408AsnAsn: 2.408 ± 1.519
1.204AsnPro: 1.204 ± 1.041
1.204AsnGln: 1.204 ± 0.852
1.806AsnArg: 1.806 ± 1.084
2.408AsnSer: 2.408 ± 0.802
4.214AsnThr: 4.214 ± 1.693
3.01AsnVal: 3.01 ± 1.278
0.602AsnTrp: 0.602 ± 0.578
3.01AsnTyr: 3.01 ± 1.489
0.0AsnXaa: 0.0 ± 0.0
Pro
3.01ProAla: 3.01 ± 0.992
0.0ProCys: 0.0 ± 0.0
3.01ProAsp: 3.01 ± 1.208
3.612ProGlu: 3.612 ± 1.56
3.01ProPhe: 3.01 ± 1.102
0.0ProGly: 0.0 ± 0.0
1.204ProHis: 1.204 ± 1.019
1.204ProIle: 1.204 ± 0.472
0.602ProLys: 0.602 ± 0.426
4.214ProLeu: 4.214 ± 1.307
1.806ProMet: 1.806 ± 1.47
3.612ProAsn: 3.612 ± 1.304
1.204ProPro: 1.204 ± 0.472
0.602ProGln: 0.602 ± 0.426
0.602ProArg: 0.602 ± 0.426
3.612ProSer: 3.612 ± 1.992
1.806ProThr: 1.806 ± 0.668
3.612ProVal: 3.612 ± 1.463
1.806ProTrp: 1.806 ± 0.905
4.214ProTyr: 4.214 ± 1.554
0.0ProXaa: 0.0 ± 0.0
Gln
3.01GlnAla: 3.01 ± 2.212
0.0GlnCys: 0.0 ± 0.0
2.408GlnAsp: 2.408 ± 1.226
1.806GlnGlu: 1.806 ± 0.836
3.01GlnPhe: 3.01 ± 0.868
2.408GlnGly: 2.408 ± 0.935
0.0GlnHis: 0.0 ± 0.0
3.612GlnIle: 3.612 ± 2.788
4.214GlnLys: 4.214 ± 2.834
2.408GlnLeu: 2.408 ± 1.07
0.602GlnMet: 0.602 ± 0.578
1.204GlnAsn: 1.204 ± 1.167
1.806GlnPro: 1.806 ± 1.278
2.408GlnGln: 2.408 ± 1.74
2.408GlnArg: 2.408 ± 0.897
4.214GlnSer: 4.214 ± 0.846
3.01GlnThr: 3.01 ± 2.13
1.806GlnVal: 1.806 ± 0.836
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.214ArgAla: 4.214 ± 1.794
1.204ArgCys: 1.204 ± 0.908
3.01ArgAsp: 3.01 ± 1.337
6.623ArgGlu: 6.623 ± 2.46
1.806ArgPhe: 1.806 ± 0.878
2.408ArgGly: 2.408 ± 1.519
1.204ArgHis: 1.204 ± 0.472
3.612ArgIle: 3.612 ± 1.373
1.806ArgLys: 1.806 ± 0.713
4.816ArgLeu: 4.816 ± 1.062
1.204ArgMet: 1.204 ± 0.807
2.408ArgAsn: 2.408 ± 0.568
2.408ArgPro: 2.408 ± 1.893
1.204ArgGln: 1.204 ± 0.581
4.816ArgArg: 4.816 ± 2.622
2.408ArgSer: 2.408 ± 1.709
3.01ArgThr: 3.01 ± 0.868
3.01ArgVal: 3.01 ± 2.181
0.602ArgTrp: 0.602 ± 0.426
4.214ArgTyr: 4.214 ± 1.304
0.0ArgXaa: 0.0 ± 0.0
Ser
10.235SerAla: 10.235 ± 2.617
0.0SerCys: 0.0 ± 0.0
9.031SerAsp: 9.031 ± 2.692
1.806SerGlu: 1.806 ± 1.278
3.01SerPhe: 3.01 ± 1.337
8.429SerGly: 8.429 ± 1.425
1.806SerHis: 1.806 ± 0.668
5.418SerIle: 5.418 ± 1.107
3.612SerLys: 3.612 ± 1.981
11.439SerLeu: 11.439 ± 2.246
1.204SerMet: 1.204 ± 1.167
3.612SerAsn: 3.612 ± 1.744
5.418SerPro: 5.418 ± 1.371
5.418SerGln: 5.418 ± 1.345
3.01SerArg: 3.01 ± 0.868
12.041SerSer: 12.041 ± 2.372
2.408SerThr: 2.408 ± 0.805
7.827SerVal: 7.827 ± 1.742
0.602SerTrp: 0.602 ± 0.578
5.418SerTyr: 5.418 ± 1.987
0.0SerXaa: 0.0 ± 0.0
Thr
2.408ThrAla: 2.408 ± 0.966
1.204ThrCys: 1.204 ± 0.472
2.408ThrAsp: 2.408 ± 0.986
2.408ThrGlu: 2.408 ± 0.778
2.408ThrPhe: 2.408 ± 1.044
5.418ThrGly: 5.418 ± 1.507
1.204ThrHis: 1.204 ± 0.7
1.204ThrIle: 1.204 ± 1.329
2.408ThrLys: 2.408 ± 1.137
5.418ThrLeu: 5.418 ± 1.781
0.602ThrMet: 0.602 ± 0.426
3.01ThrAsn: 3.01 ± 1.166
1.806ThrPro: 1.806 ± 0.921
3.01ThrGln: 3.01 ± 1.589
1.806ThrArg: 1.806 ± 0.836
11.439ThrSer: 11.439 ± 4.212
1.806ThrThr: 1.806 ± 1.084
1.806ThrVal: 1.806 ± 0.812
0.0ThrTrp: 0.0 ± 0.0
1.806ThrTyr: 1.806 ± 0.716
0.0ThrXaa: 0.0 ± 0.0
Val
3.01ValAla: 3.01 ± 2.321
0.602ValCys: 0.602 ± 0.578
3.01ValAsp: 3.01 ± 1.327
1.204ValGlu: 1.204 ± 1.339
1.806ValPhe: 1.806 ± 0.905
2.408ValGly: 2.408 ± 0.568
0.602ValHis: 0.602 ± 0.426
3.01ValIle: 3.01 ± 0.778
3.612ValLys: 3.612 ± 1.065
4.816ValLeu: 4.816 ± 0.966
1.204ValMet: 1.204 ± 0.654
1.204ValAsn: 1.204 ± 0.581
5.418ValPro: 5.418 ± 1.385
2.408ValGln: 2.408 ± 0.959
2.408ValArg: 2.408 ± 1.309
4.816ValSer: 4.816 ± 1.052
3.612ValThr: 3.612 ± 0.77
1.806ValVal: 1.806 ± 0.929
0.602ValTrp: 0.602 ± 0.426
3.01ValTyr: 3.01 ± 1.191
0.0ValXaa: 0.0 ± 0.0
Trp
0.602TrpAla: 0.602 ± 0.426
0.0TrpCys: 0.0 ± 0.0
1.204TrpAsp: 1.204 ± 0.742
0.602TrpGlu: 0.602 ± 0.578
1.204TrpPhe: 1.204 ± 0.852
0.602TrpGly: 0.602 ± 0.426
0.602TrpHis: 0.602 ± 0.578
0.0TrpIle: 0.0 ± 0.0
0.602TrpLys: 0.602 ± 0.578
0.602TrpLeu: 0.602 ± 0.426
0.0TrpMet: 0.0 ± 0.0
1.204TrpAsn: 1.204 ± 0.472
0.0TrpPro: 0.0 ± 0.0
1.204TrpGln: 1.204 ± 0.581
0.602TrpArg: 0.602 ± 0.426
0.602TrpSer: 0.602 ± 0.578
0.602TrpThr: 0.602 ± 0.793
0.602TrpVal: 0.602 ± 0.426
0.0TrpTrp: 0.0 ± 0.0
0.602TrpTyr: 0.602 ± 0.426
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.602TyrAla: 0.602 ± 0.426
0.0TyrCys: 0.0 ± 0.0
3.612TyrAsp: 3.612 ± 1.135
2.408TyrGlu: 2.408 ± 1.124
3.01TyrPhe: 3.01 ± 1.369
5.418TyrGly: 5.418 ± 2.746
2.408TyrHis: 2.408 ± 1.631
5.418TyrIle: 5.418 ± 1.909
3.01TyrLys: 3.01 ± 1.011
5.418TyrLeu: 5.418 ± 1.812
1.806TyrMet: 1.806 ± 0.965
3.01TyrAsn: 3.01 ± 1.208
2.408TyrPro: 2.408 ± 1.215
3.01TyrGln: 3.01 ± 1.375
1.204TyrArg: 1.204 ± 0.908
3.01TyrSer: 3.01 ± 1.043
1.204TyrThr: 1.204 ± 1.339
1.806TyrVal: 1.806 ± 0.689
1.204TyrTrp: 1.204 ± 1.156
1.204TyrTyr: 1.204 ± 1.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1662 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski