Amino acid dipepetide frequency for Trinickia dinghuensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.796AlaAla: 17.796 ± 0.135	1.388AlaCys: 1.388 ± 0.026	6.612AlaAsp: 6.612 ± 0.069	6.1AlaGlu: 6.1 ± 0.067	4.487AlaPhe: 4.487 ± 0.05	10.474AlaGly: 10.474 ± 0.074	2.979AlaHis: 2.979 ± 0.04	5.811AlaIle: 5.811 ± 0.055	3.844AlaLys: 3.844 ± 0.05	14.315AlaLeu: 14.315 ± 0.109	3.282AlaMet: 3.282 ± 0.044	3.242AlaAsn: 3.242 ± 0.048	6.073AlaPro: 6.073 ± 0.06	5.303AlaGln: 5.303 ± 0.062	9.237AlaArg: 9.237 ± 0.085	7.809AlaSer: 7.809 ± 0.067	6.215AlaThr: 6.215 ± 0.068	9.056AlaVal: 9.056 ± 0.079	1.622AlaTrp: 1.622 ± 0.027	2.742AlaTyr: 2.742 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	1.302CysAla: 1.302 ± 0.025	0.141CysCys: 0.141 ± 0.009	0.588CysAsp: 0.588 ± 0.016	0.531CysGlu: 0.531 ± 0.015	0.344CysPhe: 0.344 ± 0.012	1.023CysGly: 1.023 ± 0.024	0.232CysHis: 0.232 ± 0.01	0.416CysIle: 0.416 ± 0.014	0.229CysLys: 0.229 ± 0.009	0.78CysLeu: 0.78 ± 0.019	0.206CysMet: 0.206 ± 0.01	0.244CysAsn: 0.244 ± 0.01	0.467CysPro: 0.467 ± 0.018	0.207CysGln: 0.207 ± 0.01	0.635CysArg: 0.635 ± 0.018	0.561CysSer: 0.561 ± 0.015	0.513CysThr: 0.513 ± 0.015	0.817CysVal: 0.817 ± 0.019	0.12CysTrp: 0.12 ± 0.007	0.233CysTyr: 0.233 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.727AspAla: 7.727 ± 0.08	0.499AspCys: 0.499 ± 0.014	3.2AspAsp: 3.2 ± 0.04	3.611AspGlu: 3.611 ± 0.047	1.941AspPhe: 1.941 ± 0.031	4.663AspGly: 4.663 ± 0.048	1.12AspHis: 1.12 ± 0.025	2.489AspIle: 2.489 ± 0.036	1.446AspLys: 1.446 ± 0.029	5.135AspLeu: 5.135 ± 0.05	1.142AspMet: 1.142 ± 0.02	1.251AspAsn: 1.251 ± 0.032	2.943AspPro: 2.943 ± 0.039	1.505AspGln: 1.505 ± 0.026	3.529AspArg: 3.529 ± 0.038	2.555AspSer: 2.555 ± 0.038	2.798AspThr: 2.798 ± 0.046	4.377AspVal: 4.377 ± 0.045	0.932AspTrp: 0.932 ± 0.023	1.488AspTyr: 1.488 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	6.752GluAla: 6.752 ± 0.072	0.435GluCys: 0.435 ± 0.017	2.173GluAsp: 2.173 ± 0.029	2.401GluGlu: 2.401 ± 0.041	1.748GluPhe: 1.748 ± 0.032	3.529GluGly: 3.529 ± 0.041	1.571GluHis: 1.571 ± 0.031	2.863GluIle: 2.863 ± 0.043	1.757GluLys: 1.757 ± 0.036	5.413GluLeu: 5.413 ± 0.064	1.231GluMet: 1.231 ± 0.029	1.394GluAsn: 1.394 ± 0.025	2.612GluPro: 2.612 ± 0.037	2.522GluGln: 2.522 ± 0.043	5.249GluArg: 5.249 ± 0.067	2.814GluSer: 2.814 ± 0.035	2.96GluThr: 2.96 ± 0.041	3.405GluVal: 3.405 ± 0.044	0.729GluTrp: 0.729 ± 0.021	1.18GluTyr: 1.18 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.713PheAla: 4.713 ± 0.052	0.407PheCys: 0.407 ± 0.014	2.769PheAsp: 2.769 ± 0.039	2.094PheGlu: 2.094 ± 0.031	1.411PhePhe: 1.411 ± 0.027	3.729PheGly: 3.729 ± 0.043	0.738PheHis: 0.738 ± 0.02	1.563PheIle: 1.563 ± 0.031	1.07PheLys: 1.07 ± 0.021	2.92PheLeu: 2.92 ± 0.036	0.791PheMet: 0.791 ± 0.02	1.097PheAsn: 1.097 ± 0.025	1.567PhePro: 1.567 ± 0.028	0.96PheGln: 0.96 ± 0.021	1.949PheArg: 1.949 ± 0.035	2.347PheSer: 2.347 ± 0.039	1.957PheThr: 1.957 ± 0.033	3.212PheVal: 3.212 ± 0.05	0.487PheTrp: 0.487 ± 0.017	0.957PheTyr: 0.957 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.638GlyAla: 9.638 ± 0.078	0.875GlyCys: 0.875 ± 0.026	4.014GlyAsp: 4.014 ± 0.045	4.444GlyGlu: 4.444 ± 0.053	3.351GlyPhe: 3.351 ± 0.046	6.909GlyGly: 6.909 ± 0.111	1.946GlyHis: 1.946 ± 0.031	4.317GlyIle: 4.317 ± 0.045	3.152GlyLys: 3.152 ± 0.042	7.835GlyLeu: 7.835 ± 0.067	2.18GlyMet: 2.18 ± 0.035	2.429GlyAsn: 2.429 ± 0.048	2.985GlyPro: 2.985 ± 0.039	2.75GlyGln: 2.75 ± 0.039	5.23GlyArg: 5.23 ± 0.047	4.833GlySer: 4.833 ± 0.068	4.852GlyThr: 4.852 ± 0.071	6.595GlyVal: 6.595 ± 0.06	1.329GlyTrp: 1.329 ± 0.03	2.465GlyTyr: 2.465 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	3.205HisAla: 3.205 ± 0.039	0.267HisCys: 0.267 ± 0.011	1.339HisAsp: 1.339 ± 0.021	1.273HisGlu: 1.273 ± 0.029	0.926HisPhe: 0.926 ± 0.022	2.231HisGly: 2.231 ± 0.034	0.599HisHis: 0.599 ± 0.019	0.908HisIle: 0.908 ± 0.02	0.512HisLys: 0.512 ± 0.017	2.149HisLeu: 2.149 ± 0.034	0.523HisMet: 0.523 ± 0.015	0.507HisAsn: 0.507 ± 0.017	1.458HisPro: 1.458 ± 0.025	0.631HisGln: 0.631 ± 0.02	1.677HisArg: 1.677 ± 0.032	1.112HisSer: 1.112 ± 0.026	1.056HisThr: 1.056 ± 0.024	1.849HisVal: 1.849 ± 0.031	0.381HisTrp: 0.381 ± 0.013	0.693HisTyr: 0.693 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.099IleAla: 7.099 ± 0.066	0.439IleCys: 0.439 ± 0.014	3.687IleAsp: 3.687 ± 0.042	3.47IleGlu: 3.47 ± 0.043	1.392IlePhe: 1.392 ± 0.028	4.896IleGly: 4.896 ± 0.057	0.926IleHis: 0.926 ± 0.02	1.449IleIle: 1.449 ± 0.027	1.337IleLys: 1.337 ± 0.031	3.321IleLeu: 3.321 ± 0.042	0.745IleMet: 0.745 ± 0.021	1.288IleAsn: 1.288 ± 0.026	2.05IlePro: 2.05 ± 0.031	1.116IleGln: 1.116 ± 0.023	2.736IleArg: 2.736 ± 0.039	2.582IleSer: 2.582 ± 0.04	2.213IleThr: 2.213 ± 0.038	4.619IleVal: 4.619 ± 0.048	0.485IleTrp: 0.485 ± 0.014	1.034IleTyr: 1.034 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.551LysAla: 3.551 ± 0.049	0.163LysCys: 0.163 ± 0.01	1.409LysAsp: 1.409 ± 0.029	1.394LysGlu: 1.394 ± 0.028	0.888LysPhe: 0.888 ± 0.021	2.118LysGly: 2.118 ± 0.038	0.758LysHis: 0.758 ± 0.021	1.594LysIle: 1.594 ± 0.031	1.154LysLys: 1.154 ± 0.033	3.299LysLeu: 3.299 ± 0.041	0.768LysMet: 0.768 ± 0.021	0.842LysAsn: 0.842 ± 0.02	1.844LysPro: 1.844 ± 0.032	1.299LysGln: 1.299 ± 0.027	2.464LysArg: 2.464 ± 0.032	1.717LysSer: 1.717 ± 0.031	1.826LysThr: 1.826 ± 0.032	2.126LysVal: 2.126 ± 0.038	0.369LysTrp: 0.369 ± 0.015	0.689LysTyr: 0.689 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.93LeuAla: 13.93 ± 0.107	1.003LeuCys: 1.003 ± 0.022	5.911LeuAsp: 5.911 ± 0.06	5.185LeuGlu: 5.185 ± 0.059	3.549LeuPhe: 3.549 ± 0.048	8.072LeuGly: 8.072 ± 0.072	2.238LeuHis: 2.238 ± 0.034	4.53LeuIle: 4.53 ± 0.053	3.126LeuLys: 3.126 ± 0.039	9.505LeuLeu: 9.505 ± 0.09	2.223LeuMet: 2.223 ± 0.039	2.615LeuAsn: 2.615 ± 0.033	5.672LeuPro: 5.672 ± 0.054	3.116LeuGln: 3.116 ± 0.033	7.078LeuArg: 7.078 ± 0.065	6.553LeuSer: 6.553 ± 0.053	5.694LeuThr: 5.694 ± 0.058	7.484LeuVal: 7.484 ± 0.064	1.092LeuTrp: 1.092 ± 0.022	2.174LeuTyr: 2.174 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.466MetAla: 2.466 ± 0.036	0.199MetCys: 0.199 ± 0.01	0.923MetAsp: 0.923 ± 0.024	0.897MetGlu: 0.897 ± 0.019	0.722MetPhe: 0.722 ± 0.018	1.574MetGly: 1.574 ± 0.032	0.579MetHis: 0.579 ± 0.016	1.09MetIle: 1.09 ± 0.025	1.002MetLys: 1.002 ± 0.022	2.657MetLeu: 2.657 ± 0.035	0.578MetMet: 0.578 ± 0.015	0.903MetAsn: 0.903 ± 0.024	1.505MetPro: 1.505 ± 0.029	1.018MetGln: 1.018 ± 0.021	1.872MetArg: 1.872 ± 0.034	1.77MetSer: 1.77 ± 0.033	1.685MetThr: 1.685 ± 0.027	1.419MetVal: 1.419 ± 0.023	0.212MetTrp: 0.212 ± 0.011	0.388MetTyr: 0.388 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.546AsnAla: 3.546 ± 0.046	0.263AsnCys: 0.263 ± 0.011	1.489AsnAsp: 1.489 ± 0.031	1.389AsnGlu: 1.389 ± 0.028	0.988AsnPhe: 0.988 ± 0.025	2.631AsnGly: 2.631 ± 0.051	0.515AsnHis: 0.515 ± 0.015	1.194AsnIle: 1.194 ± 0.024	0.662AsnLys: 0.662 ± 0.019	2.637AsnLeu: 2.637 ± 0.035	0.562AsnMet: 0.562 ± 0.018	0.794AsnAsn: 0.794 ± 0.024	1.708AsnPro: 1.708 ± 0.031	0.854AsnGln: 0.854 ± 0.024	1.796AsnArg: 1.796 ± 0.03	1.365AsnSer: 1.365 ± 0.03	1.485AsnThr: 1.485 ± 0.033	2.303AsnVal: 2.303 ± 0.035	0.417AsnTrp: 0.417 ± 0.015	0.76AsnTyr: 0.76 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	6.414ProAla: 6.414 ± 0.065	0.379ProCys: 0.379 ± 0.016	3.018ProAsp: 3.018 ± 0.039	2.958ProGlu: 2.958 ± 0.042	1.921ProPhe: 1.921 ± 0.037	4.081ProGly: 4.081 ± 0.041	1.296ProHis: 1.296 ± 0.023	2.318ProIle: 2.318 ± 0.036	1.416ProLys: 1.416 ± 0.028	5.053ProLeu: 5.053 ± 0.053	1.127ProMet: 1.127 ± 0.021	1.544ProAsn: 1.544 ± 0.03	2.481ProPro: 2.481 ± 0.045	1.742ProGln: 1.742 ± 0.033	3.045ProArg: 3.045 ± 0.044	3.278ProSer: 3.278 ± 0.042	2.734ProThr: 2.734 ± 0.04	3.925ProVal: 3.925 ± 0.04	0.653ProTrp: 0.653 ± 0.016	1.255ProTyr: 1.255 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	4.711GlnAla: 4.711 ± 0.057	0.291GlnCys: 0.291 ± 0.011	1.269GlnAsp: 1.269 ± 0.025	1.378GlnGlu: 1.378 ± 0.027	1.301GlnPhe: 1.301 ± 0.026	2.421GlnGly: 2.421 ± 0.036	0.836GlnHis: 0.836 ± 0.021	1.869GlnIle: 1.869 ± 0.032	0.977GlnLys: 0.977 ± 0.024	3.653GlnLeu: 3.653 ± 0.046	0.951GlnMet: 0.951 ± 0.023	0.9GlnAsn: 0.9 ± 0.027	1.867GlnPro: 1.867 ± 0.033	1.642GlnGln: 1.642 ± 0.034	2.727GlnArg: 2.727 ± 0.041	2.123GlnSer: 2.123 ± 0.031	2.003GlnThr: 2.003 ± 0.034	2.391GlnVal: 2.391 ± 0.034	0.569GlnTrp: 0.569 ± 0.017	0.922GlnTyr: 0.922 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.542ArgAla: 8.542 ± 0.082	0.657ArgCys: 0.657 ± 0.02	3.705ArgAsp: 3.705 ± 0.048	4.385ArgGlu: 4.385 ± 0.056	3.064ArgPhe: 3.064 ± 0.042	4.723ArgGly: 4.723 ± 0.046	1.883ArgHis: 1.883 ± 0.032	3.729ArgIle: 3.729 ± 0.039	2.057ArgLys: 2.057 ± 0.033	7.432ArgLeu: 7.432 ± 0.071	1.883ArgMet: 1.883 ± 0.035	1.85ArgAsn: 1.85 ± 0.032	3.055ArgPro: 3.055 ± 0.039	2.459ArgGln: 2.459 ± 0.035	5.469ArgArg: 5.469 ± 0.055	3.668ArgSer: 3.668 ± 0.047	3.584ArgThr: 3.584 ± 0.044	5.172ArgVal: 5.172 ± 0.054	1.029ArgTrp: 1.029 ± 0.023	2.04ArgTyr: 2.04 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	7.232SerAla: 7.232 ± 0.076	0.488SerCys: 0.488 ± 0.017	3.024SerAsp: 3.024 ± 0.038	2.81SerGlu: 2.81 ± 0.037	2.251SerPhe: 2.251 ± 0.031	5.492SerGly: 5.492 ± 0.081	1.304SerHis: 1.304 ± 0.025	2.971SerIle: 2.971 ± 0.038	1.701SerLys: 1.701 ± 0.026	5.947SerLeu: 5.947 ± 0.059	1.503SerMet: 1.503 ± 0.027	1.786SerAsn: 1.786 ± 0.035	3.067SerPro: 3.067 ± 0.042	1.902SerGln: 1.902 ± 0.034	3.805SerArg: 3.805 ± 0.05	3.746SerSer: 3.746 ± 0.062	3.346SerThr: 3.346 ± 0.053	4.46SerVal: 4.46 ± 0.048	0.718SerTrp: 0.718 ± 0.02	1.45SerTyr: 1.45 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.167ThrAla: 6.167 ± 0.07	0.436ThrCys: 0.436 ± 0.016	2.703ThrAsp: 2.703 ± 0.04	2.433ThrGlu: 2.433 ± 0.039	2.034ThrPhe: 2.034 ± 0.038	4.776ThrGly: 4.776 ± 0.062	1.273ThrHis: 1.273 ± 0.024	2.726ThrIle: 2.726 ± 0.045	1.335ThrLys: 1.335 ± 0.023	6.426ThrLeu: 6.426 ± 0.062	1.197ThrMet: 1.197 ± 0.023	1.475ThrAsn: 1.475 ± 0.03	3.392ThrPro: 3.392 ± 0.037	1.91ThrGln: 1.91 ± 0.037	3.472ThrArg: 3.472 ± 0.042	3.227ThrSer: 3.227 ± 0.042	3.017ThrThr: 3.017 ± 0.056	4.476ThrVal: 4.476 ± 0.063	0.689ThrTrp: 0.689 ± 0.021	1.309ThrTyr: 1.309 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.51ValAla: 9.51 ± 0.069	0.854ValCys: 0.854 ± 0.019	4.45ValAsp: 4.45 ± 0.048	4.16ValGlu: 4.16 ± 0.05	2.805ValPhe: 2.805 ± 0.041	5.746ValGly: 5.746 ± 0.062	1.573ValHis: 1.573 ± 0.024	3.517ValIle: 3.517 ± 0.046	2.438ValLys: 2.438 ± 0.037	7.896ValLeu: 7.896 ± 0.074	1.789ValMet: 1.789 ± 0.03	2.133ValAsn: 2.133 ± 0.032	4.016ValPro: 4.016 ± 0.049	2.417ValGln: 2.417 ± 0.037	5.253ValArg: 5.253 ± 0.053	4.808ValSer: 4.808 ± 0.06	4.554ValThr: 4.554 ± 0.056	6.367ValVal: 6.367 ± 0.057	0.964ValTrp: 0.964 ± 0.025	1.656ValTyr: 1.656 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.211TrpAla: 1.211 ± 0.028	0.137TrpCys: 0.137 ± 0.008	0.61TrpAsp: 0.61 ± 0.019	0.524TrpGlu: 0.524 ± 0.016	0.552TrpPhe: 0.552 ± 0.018	0.865TrpGly: 0.865 ± 0.021	0.41TrpHis: 0.41 ± 0.014	0.696TrpIle: 0.696 ± 0.02	0.417TrpLys: 0.417 ± 0.014	1.874TrpLeu: 1.874 ± 0.033	0.344TrpMet: 0.344 ± 0.012	0.433TrpAsn: 0.433 ± 0.015	0.648TrpPro: 0.648 ± 0.018	0.616TrpGln: 0.616 ± 0.02	1.194TrpArg: 1.194 ± 0.026	0.796TrpSer: 0.796 ± 0.019	0.681TrpThr: 0.681 ± 0.02	0.877TrpVal: 0.877 ± 0.023	0.214TrpTrp: 0.214 ± 0.01	0.308TrpTyr: 0.308 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.872TyrAla: 2.872 ± 0.035	0.272TyrCys: 0.272 ± 0.011	1.455TyrAsp: 1.455 ± 0.031	1.303TyrGlu: 1.303 ± 0.028	1.064TyrPhe: 1.064 ± 0.024	2.175TyrGly: 2.175 ± 0.036	0.521TyrHis: 0.521 ± 0.013	0.836TyrIle: 0.836 ± 0.021	0.639TyrLys: 0.639 ± 0.017	2.506TyrLeu: 2.506 ± 0.036	0.431TyrMet: 0.431 ± 0.014	0.63TyrAsn: 0.63 ± 0.017	1.23TyrPro: 1.23 ± 0.025	0.833TyrGln: 0.833 ± 0.024	1.968TyrArg: 1.968 ± 0.034	1.34TyrSer: 1.34 ± 0.026	1.299TyrThr: 1.299 ± 0.028	1.976TyrVal: 1.976 ± 0.029	0.395TyrTrp: 0.395 ± 0.014	0.69TyrTyr: 0.69 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6498 proteins (2122929 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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