Amino acid dipepetide frequency for Bipolaris zeicola 26-R-13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.106AlaAla: 9.106 ± 0.065	1.172AlaCys: 1.172 ± 0.014	4.199AlaAsp: 4.199 ± 0.03	5.066AlaGlu: 5.066 ± 0.049	3.161AlaPhe: 3.161 ± 0.03	5.666AlaGly: 5.666 ± 0.034	1.934AlaHis: 1.934 ± 0.017	4.279AlaIle: 4.279 ± 0.037	4.388AlaLys: 4.388 ± 0.035	7.662AlaLeu: 7.662 ± 0.049	2.024AlaMet: 2.024 ± 0.019	3.165AlaAsn: 3.165 ± 0.025	5.216AlaPro: 5.216 ± 0.049	3.68AlaGln: 3.68 ± 0.035	4.961AlaArg: 4.961 ± 0.033	7.42AlaSer: 7.42 ± 0.052	5.442AlaThr: 5.442 ± 0.033	5.266AlaVal: 5.266 ± 0.037	1.187AlaTrp: 1.187 ± 0.016	2.31AlaTyr: 2.31 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.011CysAla: 1.011 ± 0.014	0.285CysCys: 0.285 ± 0.009	0.683CysAsp: 0.683 ± 0.011	0.617CysGlu: 0.617 ± 0.01	0.56CysPhe: 0.56 ± 0.01	0.985CysGly: 0.985 ± 0.016	0.341CysHis: 0.341 ± 0.008	0.772CysIle: 0.772 ± 0.01	0.578CysLys: 0.578 ± 0.011	1.224CysLeu: 1.224 ± 0.018	0.306CysMet: 0.306 ± 0.009	0.496CysAsn: 0.496 ± 0.009	0.707CysPro: 0.707 ± 0.013	0.466CysGln: 0.466 ± 0.009	0.766CysArg: 0.766 ± 0.01	0.976CysSer: 0.976 ± 0.015	0.802CysThr: 0.802 ± 0.013	0.85CysVal: 0.85 ± 0.014	0.217CysTrp: 0.217 ± 0.007	0.376CysTyr: 0.376 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.96AspAla: 4.96 ± 0.034	0.638AspCys: 0.638 ± 0.011	4.179AspAsp: 4.179 ± 0.042	4.351AspGlu: 4.351 ± 0.044	2.166AspPhe: 2.166 ± 0.024	3.787AspGly: 3.787 ± 0.027	1.194AspHis: 1.194 ± 0.016	2.999AspIle: 2.999 ± 0.024	2.492AspLys: 2.492 ± 0.025	4.668AspLeu: 4.668 ± 0.029	1.387AspMet: 1.387 ± 0.016	1.858AspAsn: 1.858 ± 0.019	3.188AspPro: 3.188 ± 0.025	1.815AspGln: 1.815 ± 0.02	2.863AspArg: 2.863 ± 0.027	3.924AspSer: 3.924 ± 0.029	3.034AspThr: 3.034 ± 0.031	3.685AspVal: 3.685 ± 0.026	0.874AspTrp: 0.874 ± 0.013	1.598AspTyr: 1.598 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.396GluAla: 5.396 ± 0.047	0.649GluCys: 0.649 ± 0.011	4.086GluAsp: 4.086 ± 0.038	5.452GluGlu: 5.452 ± 0.067	1.875GluPhe: 1.875 ± 0.017	3.733GluGly: 3.733 ± 0.031	1.465GluHis: 1.465 ± 0.015	2.923GluIle: 2.923 ± 0.025	3.902GluLys: 3.902 ± 0.036	4.928GluLeu: 4.928 ± 0.036	1.448GluMet: 1.448 ± 0.016	2.215GluAsn: 2.215 ± 0.021	2.765GluPro: 2.765 ± 0.044	2.644GluGln: 2.644 ± 0.028	3.914GluArg: 3.914 ± 0.035	3.996GluSer: 3.996 ± 0.03	3.336GluThr: 3.336 ± 0.026	3.464GluVal: 3.464 ± 0.033	0.921GluTrp: 0.921 ± 0.013	1.688GluTyr: 1.688 ± 0.017	0.001GluXaa: 0.001 ± 0.0
Phe	3.12PheAla: 3.12 ± 0.023	0.561PheCys: 0.561 ± 0.01	2.24PheAsp: 2.24 ± 0.023	2.085PheGlu: 2.085 ± 0.021	1.644PhePhe: 1.644 ± 0.021	2.838PheGly: 2.838 ± 0.026	0.863PheHis: 0.863 ± 0.014	1.748PheIle: 1.748 ± 0.02	1.586PheLys: 1.586 ± 0.018	3.341PheLeu: 3.341 ± 0.032	0.77PheMet: 0.77 ± 0.013	1.463PheAsn: 1.463 ± 0.017	1.929PhePro: 1.929 ± 0.02	1.365PheGln: 1.365 ± 0.016	1.878PheArg: 1.878 ± 0.017	2.972PheSer: 2.972 ± 0.028	2.243PheThr: 2.243 ± 0.024	2.36PheVal: 2.36 ± 0.02	0.635PheTrp: 0.635 ± 0.013	1.071PheTyr: 1.071 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.35GlyAla: 5.35 ± 0.039	0.946GlyCys: 0.946 ± 0.016	3.438GlyAsp: 3.438 ± 0.025	3.645GlyGlu: 3.645 ± 0.03	2.74GlyPhe: 2.74 ± 0.027	5.738GlyGly: 5.738 ± 0.058	1.651GlyHis: 1.651 ± 0.018	3.496GlyIle: 3.496 ± 0.027	3.637GlyLys: 3.637 ± 0.032	5.774GlyLeu: 5.774 ± 0.04	1.656GlyMet: 1.656 ± 0.02	2.525GlyAsn: 2.525 ± 0.024	3.218GlyPro: 3.218 ± 0.03	2.544GlyGln: 2.544 ± 0.025	4.015GlyArg: 4.015 ± 0.031	5.379GlySer: 5.379 ± 0.036	3.951GlyThr: 3.951 ± 0.031	4.292GlyVal: 4.292 ± 0.033	1.18GlyTrp: 1.18 ± 0.017	2.131GlyTyr: 2.131 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.039HisAla: 2.039 ± 0.022	0.378HisCys: 0.378 ± 0.01	1.338HisAsp: 1.338 ± 0.017	1.367HisGlu: 1.367 ± 0.019	0.92HisPhe: 0.92 ± 0.012	1.728HisGly: 1.728 ± 0.019	0.9HisHis: 0.9 ± 0.02	1.249HisIle: 1.249 ± 0.016	0.985HisLys: 0.985 ± 0.012	2.243HisLeu: 2.243 ± 0.021	0.551HisMet: 0.551 ± 0.009	0.894HisAsn: 0.894 ± 0.013	1.688HisPro: 1.688 ± 0.02	1.034HisGln: 1.034 ± 0.016	1.491HisArg: 1.491 ± 0.017	1.909HisSer: 1.909 ± 0.023	1.446HisThr: 1.446 ± 0.017	1.535HisVal: 1.535 ± 0.018	0.344HisTrp: 0.344 ± 0.009	0.728HisTyr: 0.728 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.375IleAla: 4.375 ± 0.03	0.746IleCys: 0.746 ± 0.013	2.846IleAsp: 2.846 ± 0.027	2.88IleGlu: 2.88 ± 0.03	1.96IlePhe: 1.96 ± 0.025	3.196IleGly: 3.196 ± 0.033	1.224IleHis: 1.224 ± 0.016	2.491IleIle: 2.491 ± 0.025	2.321IleLys: 2.321 ± 0.023	4.338IleLeu: 4.338 ± 0.036	1.036IleMet: 1.036 ± 0.013	1.816IleAsn: 1.816 ± 0.018	3.067IlePro: 3.067 ± 0.023	1.908IleGln: 1.908 ± 0.021	2.739IleArg: 2.739 ± 0.024	3.764IleSer: 3.764 ± 0.025	2.944IleThr: 2.944 ± 0.024	3.171IleVal: 3.171 ± 0.028	0.729IleTrp: 0.729 ± 0.011	1.422IleTyr: 1.422 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.427LysAla: 4.427 ± 0.041	0.54LysCys: 0.54 ± 0.011	3.004LysAsp: 3.004 ± 0.027	3.673LysGlu: 3.673 ± 0.038	1.489LysPhe: 1.489 ± 0.018	3.143LysGly: 3.143 ± 0.029	1.209LysHis: 1.209 ± 0.015	2.327LysIle: 2.327 ± 0.023	3.722LysLys: 3.722 ± 0.054	4.135LysLeu: 4.135 ± 0.034	1.082LysMet: 1.082 ± 0.014	1.926LysAsn: 1.926 ± 0.02	2.914LysPro: 2.914 ± 0.026	2.08LysGln: 2.08 ± 0.023	3.53LysArg: 3.53 ± 0.032	3.636LysSer: 3.636 ± 0.035	2.998LysThr: 2.998 ± 0.024	2.836LysVal: 2.836 ± 0.028	0.716LysTrp: 0.716 ± 0.01	1.433LysTyr: 1.433 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.645LeuAla: 7.645 ± 0.045	1.253LeuCys: 1.253 ± 0.018	4.953LeuAsp: 4.953 ± 0.035	5.241LeuGlu: 5.241 ± 0.041	3.233LeuPhe: 3.233 ± 0.028	5.643LeuGly: 5.643 ± 0.04	2.278LeuHis: 2.278 ± 0.026	3.852LeuIle: 3.852 ± 0.034	4.194LeuLys: 4.194 ± 0.034	8.024LeuLeu: 8.024 ± 0.06	1.731LeuMet: 1.731 ± 0.02	3.112LeuAsn: 3.112 ± 0.028	5.513LeuPro: 5.513 ± 0.042	3.778LeuGln: 3.778 ± 0.029	5.46LeuArg: 5.46 ± 0.037	7.006LeuSer: 7.006 ± 0.041	4.696LeuThr: 4.696 ± 0.033	5.275LeuVal: 5.275 ± 0.037	1.161LeuTrp: 1.161 ± 0.016	2.328LeuTyr: 2.328 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.233MetAla: 2.233 ± 0.021	0.278MetCys: 0.278 ± 0.007	1.272MetAsp: 1.272 ± 0.016	1.272MetGlu: 1.272 ± 0.016	0.772MetPhe: 0.772 ± 0.012	1.51MetGly: 1.51 ± 0.018	0.566MetHis: 0.566 ± 0.011	0.973MetIle: 0.973 ± 0.015	1.052MetLys: 1.052 ± 0.014	1.921MetLeu: 1.921 ± 0.022	0.592MetMet: 0.592 ± 0.011	0.832MetAsn: 0.832 ± 0.014	1.356MetPro: 1.356 ± 0.017	0.989MetGln: 0.989 ± 0.016	1.356MetArg: 1.356 ± 0.016	1.927MetSer: 1.927 ± 0.021	1.302MetThr: 1.302 ± 0.016	1.298MetVal: 1.298 ± 0.018	0.276MetTrp: 0.276 ± 0.008	0.614MetTyr: 0.614 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.343AsnAla: 3.343 ± 0.029	0.45AsnCys: 0.45 ± 0.009	1.985AsnAsp: 1.985 ± 0.02	2.042AsnGlu: 2.042 ± 0.022	1.401AsnPhe: 1.401 ± 0.018	3.046AsnGly: 3.046 ± 0.029	0.87AsnHis: 0.87 ± 0.014	2.067AsnIle: 2.067 ± 0.021	1.741AsnLys: 1.741 ± 0.019	3.191AsnLeu: 3.191 ± 0.023	0.912AsnMet: 0.912 ± 0.013	1.632AsnAsn: 1.632 ± 0.023	2.433AsnPro: 2.433 ± 0.02	1.403AsnGln: 1.403 ± 0.017	1.893AsnArg: 1.893 ± 0.019	2.778AsnSer: 2.778 ± 0.027	2.341AsnThr: 2.341 ± 0.024	2.391AsnVal: 2.391 ± 0.018	0.587AsnTrp: 0.587 ± 0.011	1.08AsnTyr: 1.08 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.459ProAla: 5.459 ± 0.054	0.576ProCys: 0.576 ± 0.011	3.059ProAsp: 3.059 ± 0.025	3.703ProGlu: 3.703 ± 0.04	2.058ProPhe: 2.058 ± 0.02	3.751ProGly: 3.751 ± 0.031	1.472ProHis: 1.472 ± 0.019	2.65ProIle: 2.65 ± 0.023	2.887ProLys: 2.887 ± 0.025	4.704ProLeu: 4.704 ± 0.033	1.165ProMet: 1.165 ± 0.017	2.349ProAsn: 2.349 ± 0.025	5.385ProPro: 5.385 ± 0.073	2.674ProGln: 2.674 ± 0.031	3.423ProArg: 3.423 ± 0.033	6.073ProSer: 6.073 ± 0.051	4.275ProThr: 4.275 ± 0.038	3.576ProVal: 3.576 ± 0.035	0.756ProTrp: 0.756 ± 0.012	1.606ProTyr: 1.606 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.535GlnAla: 3.535 ± 0.03	0.5GlnCys: 0.5 ± 0.011	2.187GlnAsp: 2.187 ± 0.021	2.439GlnGlu: 2.439 ± 0.027	1.27GlnPhe: 1.27 ± 0.016	2.504GlnGly: 2.504 ± 0.026	1.223GlnHis: 1.223 ± 0.017	1.901GlnIle: 1.901 ± 0.018	2.101GlnLys: 2.101 ± 0.021	3.404GlnLeu: 3.404 ± 0.028	0.909GlnMet: 0.909 ± 0.014	1.62GlnAsn: 1.62 ± 0.02	2.706GlnPro: 2.706 ± 0.033	2.78GlnGln: 2.78 ± 0.052	2.739GlnArg: 2.739 ± 0.025	3.22GlnSer: 3.22 ± 0.033	2.385GlnThr: 2.385 ± 0.024	2.158GlnVal: 2.158 ± 0.024	0.603GlnTrp: 0.603 ± 0.01	1.252GlnTyr: 1.252 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	4.671ArgAla: 4.671 ± 0.032	0.757ArgCys: 0.757 ± 0.012	3.201ArgAsp: 3.201 ± 0.029	3.668ArgGlu: 3.668 ± 0.034	2.089ArgPhe: 2.089 ± 0.02	3.644ArgGly: 3.644 ± 0.033	1.561ArgHis: 1.561 ± 0.019	2.992ArgIle: 2.992 ± 0.024	3.582ArgLys: 3.582 ± 0.027	5.207ArgLeu: 5.207 ± 0.036	1.39ArgMet: 1.39 ± 0.019	2.357ArgAsn: 2.357 ± 0.021	3.518ArgPro: 3.518 ± 0.035	2.616ArgGln: 2.616 ± 0.026	4.905ArgArg: 4.905 ± 0.044	4.652ArgSer: 4.652 ± 0.042	3.347ArgThr: 3.347 ± 0.025	3.234ArgVal: 3.234 ± 0.027	0.921ArgTrp: 0.921 ± 0.012	1.684ArgTyr: 1.684 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.682SerAla: 6.682 ± 0.049	0.92SerCys: 0.92 ± 0.014	4.071SerAsp: 4.071 ± 0.03	4.013SerGlu: 4.013 ± 0.03	2.956SerPhe: 2.956 ± 0.025	5.307SerGly: 5.307 ± 0.038	2.046SerHis: 2.046 ± 0.021	4.014SerIle: 4.014 ± 0.031	3.863SerLys: 3.863 ± 0.033	6.937SerLeu: 6.937 ± 0.042	1.762SerMet: 1.762 ± 0.018	3.1SerAsn: 3.1 ± 0.026	5.549SerPro: 5.549 ± 0.056	3.23SerGln: 3.23 ± 0.032	4.84SerArg: 4.84 ± 0.045	8.435SerSer: 8.435 ± 0.07	5.639SerThr: 5.639 ± 0.043	4.494SerVal: 4.494 ± 0.028	1.09SerTrp: 1.09 ± 0.015	2.13SerTyr: 2.13 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.304ThrAla: 5.304 ± 0.034	0.849ThrCys: 0.849 ± 0.014	2.795ThrAsp: 2.795 ± 0.023	3.037ThrGlu: 3.037 ± 0.029	2.271ThrPhe: 2.271 ± 0.021	4.057ThrGly: 4.057 ± 0.031	1.415ThrHis: 1.415 ± 0.017	3.145ThrIle: 3.145 ± 0.027	2.81ThrLys: 2.81 ± 0.026	5.354ThrLeu: 5.354 ± 0.037	1.268ThrMet: 1.268 ± 0.014	2.232ThrAsn: 2.232 ± 0.024	4.666ThrPro: 4.666 ± 0.045	2.231ThrGln: 2.231 ± 0.023	3.235ThrArg: 3.235 ± 0.024	5.417ThrSer: 5.417 ± 0.043	4.473ThrThr: 4.473 ± 0.04	3.676ThrVal: 3.676 ± 0.027	0.886ThrTrp: 0.886 ± 0.014	1.674ThrTyr: 1.674 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	5.257ValAla: 5.257 ± 0.036	0.865ValCys: 0.865 ± 0.015	3.556ValAsp: 3.556 ± 0.027	3.852ValGlu: 3.852 ± 0.035	2.399ValPhe: 2.399 ± 0.022	3.996ValGly: 3.996 ± 0.033	1.422ValHis: 1.422 ± 0.013	2.858ValIle: 2.858 ± 0.028	2.968ValLys: 2.968 ± 0.026	5.425ValLeu: 5.425 ± 0.046	1.331ValMet: 1.331 ± 0.016	2.167ValAsn: 2.167 ± 0.021	3.585ValPro: 3.585 ± 0.031	2.458ValGln: 2.458 ± 0.022	3.388ValArg: 3.388 ± 0.027	4.444ValSer: 4.444 ± 0.029	3.489ValThr: 3.489 ± 0.028	4.245ValVal: 4.245 ± 0.033	0.899ValTrp: 0.899 ± 0.012	1.749ValTyr: 1.749 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.144TrpAla: 1.144 ± 0.014	0.223TrpCys: 0.223 ± 0.007	0.894TrpAsp: 0.894 ± 0.015	0.827TrpGlu: 0.827 ± 0.012	0.546TrpPhe: 0.546 ± 0.011	0.963TrpGly: 0.963 ± 0.016	0.373TrpHis: 0.373 ± 0.009	0.791TrpIle: 0.791 ± 0.014	0.815TrpLys: 0.815 ± 0.012	1.316TrpLeu: 1.316 ± 0.015	0.382TrpMet: 0.382 ± 0.007	0.649TrpAsn: 0.649 ± 0.012	0.62TrpPro: 0.62 ± 0.011	0.595TrpGln: 0.595 ± 0.011	0.965TrpArg: 0.965 ± 0.014	1.074TrpSer: 1.074 ± 0.014	0.911TrpThr: 0.911 ± 0.013	0.9TrpVal: 0.9 ± 0.014	0.284TrpTrp: 0.284 ± 0.007	0.452TrpTyr: 0.452 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.247TyrAla: 2.247 ± 0.023	0.434TyrCys: 0.434 ± 0.01	1.674TyrAsp: 1.674 ± 0.019	1.57TyrGlu: 1.57 ± 0.019	1.202TyrPhe: 1.202 ± 0.018	2.07TyrGly: 2.07 ± 0.025	0.76TyrHis: 0.76 ± 0.012	1.447TyrIle: 1.447 ± 0.015	1.196TyrLys: 1.196 ± 0.014	2.582TyrLeu: 2.582 ± 0.03	0.692TyrMet: 0.692 ± 0.012	1.175TyrAsn: 1.175 ± 0.014	1.577TyrPro: 1.577 ± 0.02	1.146TyrGln: 1.146 ± 0.014	1.633TyrArg: 1.633 ± 0.016	2.075TyrSer: 2.075 ± 0.021	1.74TyrThr: 1.74 ± 0.018	1.649TyrVal: 1.649 ± 0.017	0.456TyrTrp: 0.456 ± 0.01	0.96TyrTyr: 0.96 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12851 proteins (5498859 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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