Amino acid dipepetide frequency for Tomato yellow leaf curl Indonesia virus-[Lembang]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.745AlaAla: 3.745 ± 0.887
1.873AlaCys: 1.873 ± 1.012
0.936AlaAsp: 0.936 ± 0.764
3.745AlaGlu: 3.745 ± 1.978
1.873AlaPhe: 1.873 ± 1.16
2.809AlaGly: 2.809 ± 1.165
0.936AlaHis: 0.936 ± 0.764
0.936AlaIle: 0.936 ± 0.904
4.682AlaLys: 4.682 ± 1.425
5.618AlaLeu: 5.618 ± 1.501
0.936AlaMet: 0.936 ± 0.638
1.873AlaAsn: 1.873 ± 0.892
3.745AlaPro: 3.745 ± 1.431
2.809AlaGln: 2.809 ± 1.351
2.809AlaArg: 2.809 ± 1.436
2.809AlaSer: 2.809 ± 1.549
3.745AlaThr: 3.745 ± 2.222
3.745AlaVal: 3.745 ± 2.066
0.936AlaTrp: 0.936 ± 0.638
2.809AlaTyr: 2.809 ± 1.437
0.0AlaXaa: 0.0 ± 0.0
Cys
0.936CysAla: 0.936 ± 0.977
1.873CysCys: 1.873 ± 1.808
0.0CysAsp: 0.0 ± 0.0
0.936CysGlu: 0.936 ± 0.764
0.936CysPhe: 0.936 ± 1.067
1.873CysGly: 1.873 ± 0.892
0.0CysHis: 0.0 ± 0.0
0.936CysIle: 0.936 ± 1.067
1.873CysLys: 1.873 ± 1.528
0.936CysLeu: 0.936 ± 1.285
1.873CysMet: 1.873 ± 1.013
0.936CysAsn: 0.936 ± 0.638
0.936CysPro: 0.936 ± 0.904
0.0CysGln: 0.0 ± 0.0
0.936CysArg: 0.936 ± 0.904
3.745CysSer: 3.745 ± 1.784
1.873CysThr: 1.873 ± 1.345
1.873CysVal: 1.873 ± 1.528
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.873AspAla: 1.873 ± 1.276
0.936AspCys: 0.936 ± 0.638
0.936AspAsp: 0.936 ± 0.638
1.873AspGlu: 1.873 ± 0.751
1.873AspPhe: 1.873 ± 1.012
2.809AspGly: 2.809 ± 1.915
1.873AspHis: 1.873 ± 1.402
1.873AspIle: 1.873 ± 1.528
0.936AspLys: 0.936 ± 0.638
8.427AspLeu: 8.427 ± 2.72
0.0AspMet: 0.0 ± 0.0
1.873AspAsn: 1.873 ± 1.16
2.809AspPro: 2.809 ± 1.437
1.873AspGln: 1.873 ± 1.205
1.873AspArg: 1.873 ± 1.528
4.682AspSer: 4.682 ± 1.342
2.809AspThr: 2.809 ± 1.209
7.491AspVal: 7.491 ± 1.338
1.873AspTrp: 1.873 ± 0.892
1.873AspTyr: 1.873 ± 1.092
0.0AspXaa: 0.0 ± 0.0
Glu
4.682GluAla: 4.682 ± 2.8
0.0GluCys: 0.0 ± 0.0
0.936GluAsp: 0.936 ± 0.638
2.809GluGlu: 2.809 ± 1.205
3.745GluPhe: 3.745 ± 1.978
1.873GluGly: 1.873 ± 0.751
0.0GluHis: 0.0 ± 0.0
1.873GluIle: 1.873 ± 2.135
0.936GluLys: 0.936 ± 0.638
3.745GluLeu: 3.745 ± 1.87
0.0GluMet: 0.0 ± 0.0
3.745GluAsn: 3.745 ± 2.092
3.745GluPro: 3.745 ± 0.994
0.936GluGln: 0.936 ± 0.764
1.873GluArg: 1.873 ± 1.092
3.745GluSer: 3.745 ± 1.024
0.936GluThr: 0.936 ± 0.764
0.936GluVal: 0.936 ± 0.904
2.809GluTrp: 2.809 ± 1.205
0.936GluTyr: 0.936 ± 1.067
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.936PheCys: 0.936 ± 0.764
2.809PheAsp: 2.809 ± 1.165
1.873PheGlu: 1.873 ± 0.751
0.936PhePhe: 0.936 ± 0.638
0.936PheGly: 0.936 ± 0.764
1.873PheHis: 1.873 ± 1.276
0.936PheIle: 0.936 ± 0.638
4.682PheLys: 4.682 ± 3.124
6.554PheLeu: 6.554 ± 2.584
2.809PheMet: 2.809 ± 1.165
3.745PheAsn: 3.745 ± 2.991
0.936PhePro: 0.936 ± 0.904
4.682PheGln: 4.682 ± 0.813
2.809PheArg: 2.809 ± 2.002
2.809PheSer: 2.809 ± 1.35
2.809PheThr: 2.809 ± 0.871
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.873PheTyr: 1.873 ± 1.528
0.0PheXaa: 0.0 ± 0.0
Gly
1.873GlyAla: 1.873 ± 1.276
1.873GlyCys: 1.873 ± 1.16
3.745GlyAsp: 3.745 ± 0.994
1.873GlyGlu: 1.873 ± 1.092
1.873GlyPhe: 1.873 ± 1.345
4.682GlyGly: 4.682 ± 2.078
0.936GlyHis: 0.936 ± 0.638
2.809GlyIle: 2.809 ± 0.848
5.618GlyLys: 5.618 ± 2.252
1.873GlyLeu: 1.873 ± 1.046
0.0GlyMet: 0.0 ± 0.0
2.809GlyAsn: 2.809 ± 1.411
2.809GlyPro: 2.809 ± 1.374
1.873GlyGln: 1.873 ± 1.528
2.809GlyArg: 2.809 ± 1.915
1.873GlySer: 1.873 ± 1.205
3.745GlyThr: 3.745 ± 1.501
4.682GlyVal: 4.682 ± 2.74
0.0GlyTrp: 0.0 ± 0.0
0.936GlyTyr: 0.936 ± 0.904
0.0GlyXaa: 0.0 ± 0.0
His
0.936HisAla: 0.936 ± 0.764
3.745HisCys: 3.745 ± 1.949
1.873HisAsp: 1.873 ± 1.046
1.873HisGlu: 1.873 ± 0.892
1.873HisPhe: 1.873 ± 1.276
1.873HisGly: 1.873 ± 1.345
1.873HisHis: 1.873 ± 1.402
2.809HisIle: 2.809 ± 3.856
0.936HisLys: 0.936 ± 0.904
1.873HisLeu: 1.873 ± 1.276
0.0HisMet: 0.0 ± 0.0
3.745HisAsn: 3.745 ± 1.935
1.873HisPro: 1.873 ± 1.092
1.873HisGln: 1.873 ± 0.751
3.745HisArg: 3.745 ± 2.066
0.936HisSer: 0.936 ± 1.067
2.809HisThr: 2.809 ± 2.292
1.873HisVal: 1.873 ± 1.092
0.0HisTrp: 0.0 ± 0.0
0.936HisTyr: 0.936 ± 0.638
0.0HisXaa: 0.0 ± 0.0
Ile
3.745IleAla: 3.745 ± 1.375
0.936IleCys: 0.936 ± 0.638
2.809IleAsp: 2.809 ± 1.436
1.873IleGlu: 1.873 ± 1.017
1.873IlePhe: 1.873 ± 1.276
0.0IleGly: 0.0 ± 0.0
0.936IleHis: 0.936 ± 1.067
0.936IleIle: 0.936 ± 0.977
6.554IleLys: 6.554 ± 1.65
3.745IleLeu: 3.745 ± 1.077
0.0IleMet: 0.0 ± 0.0
3.745IleAsn: 3.745 ± 0.887
1.873IlePro: 1.873 ± 1.205
4.682IleGln: 4.682 ± 1.554
5.618IleArg: 5.618 ± 2.114
4.682IleSer: 4.682 ± 3.94
3.745IleThr: 3.745 ± 1.776
0.936IleVal: 0.936 ± 0.638
2.809IleTrp: 2.809 ± 1.704
2.809IleTyr: 2.809 ± 1.488
0.0IleXaa: 0.0 ± 0.0
Lys
3.745LysAla: 3.745 ± 1.935
0.0LysCys: 0.0 ± 0.0
1.873LysAsp: 1.873 ± 1.276
4.682LysGlu: 4.682 ± 1.684
3.745LysPhe: 3.745 ± 1.189
0.936LysGly: 0.936 ± 0.638
1.873LysHis: 1.873 ± 1.205
6.554LysIle: 6.554 ± 1.405
3.745LysLys: 3.745 ± 1.692
0.0LysLeu: 0.0 ± 0.0
0.936LysMet: 0.936 ± 1.054
5.618LysAsn: 5.618 ± 2.33
0.936LysPro: 0.936 ± 0.764
0.936LysGln: 0.936 ± 0.638
4.682LysArg: 4.682 ± 1.722
7.491LysSer: 7.491 ± 1.63
3.745LysThr: 3.745 ± 1.077
4.682LysVal: 4.682 ± 2.164
0.0LysTrp: 0.0 ± 0.0
4.682LysTyr: 4.682 ± 1.107
0.0LysXaa: 0.0 ± 0.0
Leu
1.873LeuAla: 1.873 ± 1.017
1.873LeuCys: 1.873 ± 1.276
4.682LeuAsp: 4.682 ± 1.791
3.745LeuGlu: 3.745 ± 1.935
3.745LeuPhe: 3.745 ± 2.474
5.618LeuGly: 5.618 ± 1.722
3.745LeuHis: 3.745 ± 1.935
1.873LeuIle: 1.873 ± 1.017
6.554LeuLys: 6.554 ± 0.998
3.745LeuLeu: 3.745 ± 1.733
0.936LeuMet: 0.936 ± 0.919
10.3LeuAsn: 10.3 ± 1.775
0.936LeuPro: 0.936 ± 0.904
3.745LeuGln: 3.745 ± 1.582
6.554LeuArg: 6.554 ± 2.002
4.682LeuSer: 4.682 ± 1.897
5.618LeuThr: 5.618 ± 0.857
3.745LeuVal: 3.745 ± 1.191
0.0LeuTrp: 0.0 ± 0.0
4.682LeuTyr: 4.682 ± 1.135
0.0LeuXaa: 0.0 ± 0.0
Met
0.936MetAla: 0.936 ± 0.764
1.873MetCys: 1.873 ± 1.54
2.809MetAsp: 2.809 ± 0.848
0.936MetGlu: 0.936 ± 0.638
1.873MetPhe: 1.873 ± 1.528
1.873MetGly: 1.873 ± 1.205
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.873MetLeu: 1.873 ± 1.012
0.0MetMet: 0.0 ± 0.0
0.936MetAsn: 0.936 ± 0.638
0.0MetPro: 0.0 ± 0.0
0.936MetGln: 0.936 ± 0.977
0.936MetArg: 0.936 ± 0.764
0.936MetSer: 0.936 ± 1.285
0.936MetThr: 0.936 ± 0.638
0.936MetVal: 0.936 ± 1.285
1.873MetTrp: 1.873 ± 1.017
1.873MetTyr: 1.873 ± 1.528
0.0MetXaa: 0.0 ± 0.0
Asn
4.682AsnAla: 4.682 ± 2.322
1.873AsnCys: 1.873 ± 1.954
2.809AsnAsp: 2.809 ± 1.165
1.873AsnGlu: 1.873 ± 1.012
0.0AsnPhe: 0.0 ± 0.0
1.873AsnGly: 1.873 ± 1.677
6.554AsnHis: 6.554 ± 2.899
5.618AsnIle: 5.618 ± 2.118
2.809AsnLys: 2.809 ± 1.915
5.618AsnLeu: 5.618 ± 2.445
1.873AsnMet: 1.873 ± 1.445
4.682AsnAsn: 4.682 ± 1.759
2.809AsnPro: 2.809 ± 0.848
0.936AsnGln: 0.936 ± 1.285
1.873AsnArg: 1.873 ± 0.751
2.809AsnSer: 2.809 ± 1.209
6.554AsnThr: 6.554 ± 1.482
1.873AsnVal: 1.873 ± 1.092
0.936AsnTrp: 0.936 ± 0.638
4.682AsnTyr: 4.682 ± 1.392
0.0AsnXaa: 0.0 ± 0.0
Pro
2.809ProAla: 2.809 ± 1.205
1.873ProCys: 1.873 ± 1.012
5.618ProAsp: 5.618 ± 2.773
2.809ProGlu: 2.809 ± 1.209
1.873ProPhe: 1.873 ± 1.092
0.936ProGly: 0.936 ± 0.764
2.809ProHis: 2.809 ± 1.915
1.873ProIle: 1.873 ± 0.892
2.809ProLys: 2.809 ± 1.915
5.618ProLeu: 5.618 ± 1.546
1.873ProMet: 1.873 ± 1.54
1.873ProAsn: 1.873 ± 1.017
0.936ProPro: 0.936 ± 1.067
3.745ProGln: 3.745 ± 1.446
5.618ProArg: 5.618 ± 1.83
7.491ProSer: 7.491 ± 3.812
4.682ProThr: 4.682 ± 2.498
3.745ProVal: 3.745 ± 1.375
0.0ProTrp: 0.0 ± 0.0
0.936ProTyr: 0.936 ± 0.764
0.0ProXaa: 0.0 ± 0.0
Gln
1.873GlnAla: 1.873 ± 1.677
0.936GlnCys: 0.936 ± 1.067
2.809GlnAsp: 2.809 ± 1.35
1.873GlnGlu: 1.873 ± 1.16
2.809GlnPhe: 2.809 ± 1.436
2.809GlnGly: 2.809 ± 1.437
2.809GlnHis: 2.809 ± 2.402
3.745GlnIle: 3.745 ± 2.553
0.0GlnLys: 0.0 ± 0.0
0.936GlnLeu: 0.936 ± 0.904
0.936GlnMet: 0.936 ± 0.638
1.873GlnAsn: 1.873 ± 1.402
8.427GlnPro: 8.427 ± 4.2
0.0GlnGln: 0.0 ± 0.0
0.936GlnArg: 0.936 ± 1.285
3.745GlnSer: 3.745 ± 1.722
0.936GlnThr: 0.936 ± 0.764
4.682GlnVal: 4.682 ± 1.135
0.0GlnTrp: 0.0 ± 0.0
0.936GlnTyr: 0.936 ± 0.764
0.0GlnXaa: 0.0 ± 0.0
Arg
3.745ArgAla: 3.745 ± 1.511
1.873ArgCys: 1.873 ± 1.401
4.682ArgAsp: 4.682 ± 2.35
0.936ArgGlu: 0.936 ± 1.285
3.745ArgPhe: 3.745 ± 1.501
5.618ArgGly: 5.618 ± 1.597
2.809ArgHis: 2.809 ± 0.902
3.745ArgIle: 3.745 ± 1.733
4.682ArgLys: 4.682 ± 2.821
3.745ArgLeu: 3.745 ± 1.629
1.873ArgMet: 1.873 ± 1.54
1.873ArgAsn: 1.873 ± 1.092
6.554ArgPro: 6.554 ± 1.974
1.873ArgGln: 1.873 ± 1.419
7.491ArgArg: 7.491 ± 4.249
3.745ArgSer: 3.745 ± 1.978
6.554ArgThr: 6.554 ± 3.04
2.809ArgVal: 2.809 ± 1.411
0.0ArgTrp: 0.0 ± 0.0
1.873ArgTyr: 1.873 ± 1.808
0.0ArgXaa: 0.0 ± 0.0
Ser
1.873SerAla: 1.873 ± 1.017
0.0SerCys: 0.0 ± 0.0
2.809SerAsp: 2.809 ± 1.759
1.873SerGlu: 1.873 ± 1.276
1.873SerPhe: 1.873 ± 0.751
1.873SerGly: 1.873 ± 0.751
1.873SerHis: 1.873 ± 1.092
4.682SerIle: 4.682 ± 2.991
6.554SerLys: 6.554 ± 3.685
8.427SerLeu: 8.427 ± 2.443
0.936SerMet: 0.936 ± 1.398
6.554SerAsn: 6.554 ± 1.994
5.618SerPro: 5.618 ± 1.733
3.745SerGln: 3.745 ± 1.949
8.427SerArg: 8.427 ± 1.374
11.236SerSer: 11.236 ± 3.489
3.745SerThr: 3.745 ± 1.327
2.809SerVal: 2.809 ± 2.073
0.936SerTrp: 0.936 ± 0.764
1.873SerTyr: 1.873 ± 0.892
0.0SerXaa: 0.0 ± 0.0
Thr
6.554ThrAla: 6.554 ± 3.527
0.0ThrCys: 0.0 ± 0.0
0.936ThrAsp: 0.936 ± 0.764
0.936ThrGlu: 0.936 ± 0.764
2.809ThrPhe: 2.809 ± 1.503
4.682ThrGly: 4.682 ± 1.794
4.682ThrHis: 4.682 ± 1.342
2.809ThrIle: 2.809 ± 2.063
3.745ThrLys: 3.745 ± 1.722
3.745ThrLeu: 3.745 ± 1.501
0.936ThrMet: 0.936 ± 0.638
4.682ThrAsn: 4.682 ± 1.194
6.554ThrPro: 6.554 ± 1.718
2.809ThrGln: 2.809 ± 2.168
2.809ThrArg: 2.809 ± 1.321
3.745ThrSer: 3.745 ± 1.501
0.0ThrThr: 0.0 ± 0.0
3.745ThrVal: 3.745 ± 2.222
0.0ThrTrp: 0.0 ± 0.0
2.809ThrTyr: 2.809 ± 1.351
0.0ThrXaa: 0.0 ± 0.0
Val
0.936ValAla: 0.936 ± 0.638
0.0ValCys: 0.0 ± 0.0
3.745ValAsp: 3.745 ± 1.325
0.936ValGlu: 0.936 ± 0.904
3.745ValPhe: 3.745 ± 0.887
2.809ValGly: 2.809 ± 1.35
1.873ValHis: 1.873 ± 1.345
4.682ValIle: 4.682 ± 3.273
2.809ValLys: 2.809 ± 1.374
6.554ValLeu: 6.554 ± 1.604
1.873ValMet: 1.873 ± 1.528
0.0ValAsn: 0.0 ± 0.0
6.554ValPro: 6.554 ± 2.392
3.745ValGln: 3.745 ± 3.057
4.682ValArg: 4.682 ± 2.502
3.745ValSer: 3.745 ± 1.446
1.873ValThr: 1.873 ± 1.528
3.745ValVal: 3.745 ± 2.222
0.936ValTrp: 0.936 ± 1.067
3.745ValTyr: 3.745 ± 1.189
0.0ValXaa: 0.0 ± 0.0
Trp
1.873TrpAla: 1.873 ± 0.892
0.0TrpCys: 0.0 ± 0.0
0.936TrpAsp: 0.936 ± 0.904
0.936TrpGlu: 0.936 ± 1.067
0.0TrpPhe: 0.0 ± 0.0
0.936TrpGly: 0.936 ± 0.638
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.936TrpMet: 0.936 ± 0.764
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.936TrpGln: 0.936 ± 0.638
0.936TrpArg: 0.936 ± 0.977
0.936TrpSer: 0.936 ± 0.638
1.873TrpThr: 1.873 ± 1.046
0.936TrpVal: 0.936 ± 0.638
0.0TrpTrp: 0.0 ± 0.0
1.873TrpTyr: 1.873 ± 1.205
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.682TyrAla: 4.682 ± 1.808
0.0TyrCys: 0.0 ± 0.0
2.809TyrAsp: 2.809 ± 1.549
1.873TyrGlu: 1.873 ± 1.046
2.809TyrPhe: 2.809 ± 0.848
1.873TyrGly: 1.873 ± 0.751
0.0TyrHis: 0.0 ± 0.0
5.618TyrIle: 5.618 ± 2.036
0.936TyrLys: 0.936 ± 0.638
5.618TyrLeu: 5.618 ± 2.196
1.873TyrMet: 1.873 ± 1.064
1.873TyrAsn: 1.873 ± 0.751
1.873TyrPro: 1.873 ± 1.205
0.936TyrGln: 0.936 ± 0.904
2.809TyrArg: 2.809 ± 2.292
2.809TyrSer: 2.809 ± 1.437
0.0TyrThr: 0.0 ± 0.0
3.745TyrVal: 3.745 ± 1.733
0.0TyrTrp: 0.0 ± 0.0
0.936TyrTyr: 0.936 ± 0.977
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1069 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski