Human papillomavirus 126

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 11

Average proteome isoelectric point is 6.1

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|G5ELP1|G5ELP1_9PAPI Replication protein E1 OS=Human papillomavirus 126 OX=1055684 GN=HpV126gp3 PE=3 SV=1
MM1 pKa = 7.17MGKK4 pKa = 9.39EE5 pKa = 4.06CTLNDD10 pKa = 3.0IVLQEE15 pKa = 4.09NVEE18 pKa = 4.31DD19 pKa = 4.16LVLPAPLLCEE29 pKa = 4.05EE30 pKa = 4.84SSLSIDD36 pKa = 3.6DD37 pKa = 4.04TPEE40 pKa = 3.87EE41 pKa = 4.38EE42 pKa = 4.56LLSPYY47 pKa = 10.39RR48 pKa = 11.84VDD50 pKa = 4.92SYY52 pKa = 11.73CFYY55 pKa = 10.75CNRR58 pKa = 11.84GVRR61 pKa = 11.84LSVVASDD68 pKa = 3.61GAVYY72 pKa = 10.93LLQQLLLKK80 pKa = 10.41DD81 pKa = 3.64LTIVCPSCTRR91 pKa = 11.84QNLQNGRR98 pKa = 11.84SHH100 pKa = 7.1

Molecular weight: 11.19 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G5ELP3|G5ELP3_9PAPI Uncharacterized protein HpV126gp5 OS=Human papillomavirus 126 OX=1055684 GN=HpV126gp5 PE=4 SV=1
MM1 pKa = 6.96NQNDD5 pKa = 3.41LRR7 pKa = 11.84EE8 pKa = 4.3RR9 pKa = 11.84LDD11 pKa = 3.7ALQTEE16 pKa = 5.01LMTLYY21 pKa = 7.84EE22 pKa = 4.4TNPTDD27 pKa = 3.76LKK29 pKa = 11.26SQITHH34 pKa = 5.25YY35 pKa = 10.8QLLRR39 pKa = 11.84KK40 pKa = 9.8EE41 pKa = 4.97GVLQYY46 pKa = 7.46YY47 pKa = 7.12TRR49 pKa = 11.84KK50 pKa = 9.97EE51 pKa = 4.18GYY53 pKa = 9.85DD54 pKa = 3.44RR55 pKa = 11.84LGLQYY60 pKa = 10.38IPPLKK65 pKa = 9.96ISEE68 pKa = 4.24NHH70 pKa = 6.13AKK72 pKa = 8.96TAIKK76 pKa = 9.52MILILEE82 pKa = 4.23SLAKK86 pKa = 9.94SKK88 pKa = 10.7YY89 pKa = 10.37ASEE92 pKa = 3.73QWTFADD98 pKa = 4.58CSADD102 pKa = 3.49RR103 pKa = 11.84FNSPPRR109 pKa = 11.84NCLKK113 pKa = 10.23KK114 pKa = 9.9HH115 pKa = 4.64SFEE118 pKa = 4.29VEE120 pKa = 3.53VWFDD124 pKa = 3.29SDD126 pKa = 3.38KK127 pKa = 11.53QNAFPYY133 pKa = 10.33INWRR137 pKa = 11.84DD138 pKa = 3.16IYY140 pKa = 11.15YY141 pKa = 10.02QDD143 pKa = 5.67EE144 pKa = 3.98KK145 pKa = 11.7DD146 pKa = 3.17EE147 pKa = 3.96WHH149 pKa = 6.16KK150 pKa = 11.56VKK152 pKa = 11.28GEE154 pKa = 3.58VDD156 pKa = 3.54YY157 pKa = 11.84NGLFFTEE164 pKa = 4.43LDD166 pKa = 3.21GTRR169 pKa = 11.84NYY171 pKa = 10.64FILFEE176 pKa = 5.48KK177 pKa = 10.84DD178 pKa = 2.36AFRR181 pKa = 11.84YY182 pKa = 9.49GKK184 pKa = 8.73TGTWTVNYY192 pKa = 9.87DD193 pKa = 3.39NEE195 pKa = 4.46QILPFVTSSSRR206 pKa = 11.84KK207 pKa = 9.7SISDD211 pKa = 3.46TQEE214 pKa = 3.57DD215 pKa = 4.82TTTGEE220 pKa = 4.3PSTSLSTSKK229 pKa = 10.89EE230 pKa = 3.4KK231 pKa = 10.79DD232 pKa = 3.02NRR234 pKa = 11.84RR235 pKa = 11.84RR236 pKa = 11.84TPGSQEE242 pKa = 3.86GSPSSTTRR250 pKa = 11.84HH251 pKa = 4.04GRR253 pKa = 11.84RR254 pKa = 11.84RR255 pKa = 11.84RR256 pKa = 11.84RR257 pKa = 11.84GGEE260 pKa = 3.68QRR262 pKa = 11.84EE263 pKa = 4.17SPPRR267 pKa = 11.84NKK269 pKa = 9.61RR270 pKa = 11.84RR271 pKa = 11.84RR272 pKa = 11.84GAQTDD277 pKa = 3.52GTADD281 pKa = 3.7YY282 pKa = 10.48ISPEE286 pKa = 4.16EE287 pKa = 3.91VGGSHH292 pKa = 7.4RR293 pKa = 11.84SVQRR297 pKa = 11.84TGLGRR302 pKa = 11.84IEE304 pKa = 4.07RR305 pKa = 11.84LKK307 pKa = 11.09EE308 pKa = 3.65EE309 pKa = 4.63ARR311 pKa = 11.84DD312 pKa = 3.67PPIIQLKK319 pKa = 10.42GGANSLKK326 pKa = 10.07CWRR329 pKa = 11.84NRR331 pKa = 11.84FKK333 pKa = 10.66IKK335 pKa = 10.91YY336 pKa = 8.53KK337 pKa = 10.9DD338 pKa = 3.6LFTAITTVYY347 pKa = 10.24KK348 pKa = 10.25WVGNNNADD356 pKa = 3.73EE357 pKa = 4.43VEE359 pKa = 4.2SRR361 pKa = 11.84LMVAFRR367 pKa = 11.84DD368 pKa = 3.79LSQRR372 pKa = 11.84SAFIATVHH380 pKa = 5.85IPKK383 pKa = 9.9GVSMSLGSLDD393 pKa = 3.83SLL395 pKa = 4.57

Molecular weight: 45.65 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2439

100

607

348.4

39.46

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.453 ± 0.502

2.501 ± 0.905

6.56 ± 0.267

6.765 ± 0.598

4.715 ± 0.586

5.248 ± 0.763

1.804 ± 0.283

5.863 ± 0.53

5.781 ± 1.004

9.594 ± 1.127

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.763 ± 0.305

4.92 ± 0.426

6.15 ± 0.948

3.608 ± 0.247

5.904 ± 0.768

7.462 ± 0.636

6.396 ± 0.763

5.248 ± 0.435

1.23 ± 0.251

3.034 ± 0.301
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski