Human papillomavirus type 128

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 13

Average proteome isoelectric point is 6.11

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E7BRR3|E7BRR3_9PAPI Major capsid protein L1 OS=Human papillomavirus type 128 OX=931209 GN=L1 PE=3 SV=1
MM1 pKa = 7.47SKK3 pKa = 10.13PRR5 pKa = 11.84RR6 pKa = 11.84KK7 pKa = 9.6RR8 pKa = 11.84ASPEE12 pKa = 3.7DD13 pKa = 4.06LYY15 pKa = 11.46KK16 pKa = 10.8SCALGGDD23 pKa = 4.58CFPDD27 pKa = 3.44VQNKK31 pKa = 8.71IQGTTLADD39 pKa = 3.66RR40 pKa = 11.84LQVFGSILYY49 pKa = 10.33FGGLGIGSGKK59 pKa = 8.42GTGGATGYY67 pKa = 10.57RR68 pKa = 11.84PFGGGGTVSRR78 pKa = 11.84PSIRR82 pKa = 11.84IQPEE86 pKa = 4.21SLPKK90 pKa = 10.08PSVPIDD96 pKa = 3.59PLGGAEE102 pKa = 5.65LIPLDD107 pKa = 4.78VIDD110 pKa = 4.04ATAPSVVPLTEE121 pKa = 4.48GVPEE125 pKa = 4.04TTIISSGTGPTITAEE140 pKa = 4.13EE141 pKa = 4.65LDD143 pKa = 3.91VTTQIDD149 pKa = 4.63LNTFNNINEE158 pKa = 4.26HH159 pKa = 5.94PAVINVTDD167 pKa = 3.91EE168 pKa = 4.0GTTALDD174 pKa = 3.9VQTLPPPSKK183 pKa = 10.7KK184 pKa = 10.57LILDD188 pKa = 3.54STITDD193 pKa = 3.65QIEE196 pKa = 4.31LVPLHH201 pKa = 7.18RR202 pKa = 11.84IYY204 pKa = 10.88TDD206 pKa = 3.0QNVNMFVDD214 pKa = 3.58THH216 pKa = 6.72FEE218 pKa = 3.87GHH220 pKa = 6.12IVGGDD225 pKa = 3.44PNFTDD230 pKa = 2.86IVLRR234 pKa = 11.84EE235 pKa = 3.79QFEE238 pKa = 4.28IEE240 pKa = 4.21EE241 pKa = 4.28VSPKK245 pKa = 10.32TSTPTEE251 pKa = 4.11KK252 pKa = 10.78LSTAVGKK259 pKa = 10.31ARR261 pKa = 11.84RR262 pKa = 11.84VYY264 pKa = 10.76NRR266 pKa = 11.84FVKK269 pKa = 9.98QVPTSSLEE277 pKa = 3.97AVVNPSRR284 pKa = 11.84QVIFEE289 pKa = 4.13IEE291 pKa = 3.91NPAFDD296 pKa = 5.5DD297 pKa = 4.18EE298 pKa = 5.01VSLLFNQEE306 pKa = 3.88LAEE309 pKa = 4.36VTATPNPDD317 pKa = 3.09FRR319 pKa = 11.84DD320 pKa = 3.2INYY323 pKa = 9.78LSRR326 pKa = 11.84PFYY329 pKa = 11.11SEE331 pKa = 4.17TEE333 pKa = 4.13SGRR336 pKa = 11.84VQYY339 pKa = 11.13SRR341 pKa = 11.84LGQRR345 pKa = 11.84ASMQTRR351 pKa = 11.84SGLVIGEE358 pKa = 4.21KK359 pKa = 10.66VQFTYY364 pKa = 10.76NISDD368 pKa = 3.74IEE370 pKa = 4.03PVEE373 pKa = 4.23TIEE376 pKa = 5.66LSTLGTTSADD386 pKa = 3.77SIIQNAQAEE395 pKa = 4.91SVFIDD400 pKa = 4.05AQDD403 pKa = 3.9STPLTYY409 pKa = 10.53TEE411 pKa = 4.94DD412 pKa = 3.61QLLDD416 pKa = 3.66EE417 pKa = 5.28PNEE420 pKa = 4.31DD421 pKa = 3.27FANAHH426 pKa = 6.24LVLTTTDD433 pKa = 4.35DD434 pKa = 4.09FGDD437 pKa = 3.73TYY439 pKa = 10.64DD440 pKa = 4.26YY441 pKa = 11.27PVIPPGLGYY450 pKa = 11.02KK451 pKa = 10.4LLIPNYY457 pKa = 9.69NVTLSSFQLPEE468 pKa = 3.98ASVPTILPEE477 pKa = 4.3IPFAPYY483 pKa = 9.87APSPITVFGDD493 pKa = 3.59TFYY496 pKa = 11.49LNPSLLKK503 pKa = 10.31RR504 pKa = 11.84KK505 pKa = 9.51RR506 pKa = 11.84KK507 pKa = 9.25QYY509 pKa = 10.69FYY511 pKa = 11.61

Molecular weight: 55.91 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E7BRR1|E7BRR1_9PAPI E4 OS=Human papillomavirus type 128 OX=931209 GN=E4 PE=4 SV=1
MM1 pKa = 6.98NQAEE5 pKa = 4.38LTRR8 pKa = 11.84RR9 pKa = 11.84FDD11 pKa = 3.79ALQDD15 pKa = 3.67EE16 pKa = 4.46QLNLYY21 pKa = 7.5EE22 pKa = 4.64TGADD26 pKa = 3.75DD27 pKa = 4.0LQSQIRR33 pKa = 11.84HH34 pKa = 5.39WEE36 pKa = 3.74LTKK39 pKa = 10.68QLNLYY44 pKa = 8.16MFYY47 pKa = 10.83GRR49 pKa = 11.84KK50 pKa = 9.24EE51 pKa = 4.14GYY53 pKa = 8.93TNFGMQRR60 pKa = 11.84LPILQVSEE68 pKa = 4.49YY69 pKa = 9.33NAKK72 pKa = 9.98IAINMLILLKK82 pKa = 10.81SLANSKK88 pKa = 10.67FKK90 pKa = 10.81DD91 pKa = 3.96EE92 pKa = 4.61KK93 pKa = 9.25WTLSDD98 pKa = 3.42TSSDD102 pKa = 4.27LMLTPPRR109 pKa = 11.84NTFKK113 pKa = 10.94KK114 pKa = 9.62SAYY117 pKa = 6.62QVKK120 pKa = 9.67VEE122 pKa = 4.47FDD124 pKa = 3.42NDD126 pKa = 3.65PEE128 pKa = 4.52NFFLYY133 pKa = 10.14TNWDD137 pKa = 3.58EE138 pKa = 5.89IYY140 pKa = 11.11YY141 pKa = 10.26QDD143 pKa = 6.23LSDD146 pKa = 4.39KK147 pKa = 8.33WHH149 pKa = 5.89KK150 pKa = 8.56TQGKK154 pKa = 8.73VDD156 pKa = 3.65HH157 pKa = 6.93NGLYY161 pKa = 10.43FDD163 pKa = 6.32DD164 pKa = 4.37ISGDD168 pKa = 3.26RR169 pKa = 11.84NYY171 pKa = 10.86FLLFSPEE178 pKa = 3.81SEE180 pKa = 4.44KK181 pKa = 11.19YY182 pKa = 10.7GKK184 pKa = 8.24TGLWTVHH191 pKa = 5.75YY192 pKa = 9.76KK193 pKa = 9.06STTISSVVTSSSKK206 pKa = 10.61LSSGGYY212 pKa = 9.29SGQPSDD218 pKa = 3.53ISRR221 pKa = 11.84SSSRR225 pKa = 11.84CSSPQEE231 pKa = 3.96GTSRR235 pKa = 11.84RR236 pKa = 11.84CEE238 pKa = 3.73EE239 pKa = 3.92TRR241 pKa = 11.84QKK243 pKa = 11.03GSSYY247 pKa = 11.04DD248 pKa = 3.66SPTSTVGSGRR258 pKa = 11.84GKK260 pKa = 10.17RR261 pKa = 11.84KK262 pKa = 9.89RR263 pKa = 11.84EE264 pKa = 4.11SEE266 pKa = 4.22SKK268 pKa = 10.51SPSRR272 pKa = 11.84RR273 pKa = 11.84PARR276 pKa = 11.84KK277 pKa = 9.0RR278 pKa = 11.84RR279 pKa = 11.84VHH281 pKa = 6.66SEE283 pKa = 4.08LSPVSAEE290 pKa = 3.98EE291 pKa = 3.44VGRR294 pKa = 11.84RR295 pKa = 11.84HH296 pKa = 6.67RR297 pKa = 11.84SLPRR301 pKa = 11.84HH302 pKa = 5.13GLSRR306 pKa = 11.84LGRR309 pKa = 11.84LEE311 pKa = 4.52AEE313 pKa = 4.24ARR315 pKa = 11.84DD316 pKa = 3.91PDD318 pKa = 3.85VLLVKK323 pKa = 10.79GSANNLKK330 pKa = 9.67CWRR333 pKa = 11.84YY334 pKa = 9.0RR335 pKa = 11.84CEE337 pKa = 4.13KK338 pKa = 10.65KK339 pKa = 10.43FGHH342 pKa = 6.76LFSFISSVFRR352 pKa = 11.84WINDD356 pKa = 3.4DD357 pKa = 4.78FSQHH361 pKa = 5.2YY362 pKa = 10.08NSRR365 pKa = 11.84LLVAFEE371 pKa = 4.97NRR373 pKa = 11.84DD374 pKa = 3.34QRR376 pKa = 11.84NQFLMSVTFPKK387 pKa = 10.16QSSYY391 pKa = 11.05VFGSLDD397 pKa = 3.37SLL399 pKa = 4.17

Molecular weight: 46.14 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2421

96

605

345.9

39.27

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.915 ± 0.561

2.23 ± 0.763

6.526 ± 0.221

6.072 ± 0.345

5.081 ± 0.388

5.411 ± 0.528

1.817 ± 0.263

4.915 ± 0.61

5.535 ± 0.581

9.748 ± 0.62

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.652 ± 0.26

5.659 ± 0.588

5.535 ± 1.012

4.833 ± 0.327

5.411 ± 0.832

7.972 ± 1.171

6.237 ± 0.827

5.659 ± 0.612

1.239 ± 0.275

3.552 ± 0.388
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski