Amino acid dipepetide frequency for Nocardioides currus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.79AlaAla: 18.79 ± 0.197
0.97AlaCys: 0.97 ± 0.024
8.653AlaAsp: 8.653 ± 0.082
7.501AlaGlu: 7.501 ± 0.088
3.559AlaPhe: 3.559 ± 0.056
12.158AlaGly: 12.158 ± 0.104
2.576AlaHis: 2.576 ± 0.05
4.731AlaIle: 4.731 ± 0.069
2.51AlaLys: 2.51 ± 0.054
13.155AlaLeu: 13.155 ± 0.137
2.849AlaMet: 2.849 ± 0.046
2.123AlaAsn: 2.123 ± 0.047
6.159AlaPro: 6.159 ± 0.093
3.391AlaGln: 3.391 ± 0.056
9.271AlaArg: 9.271 ± 0.089
6.851AlaSer: 6.851 ± 0.078
8.066AlaThr: 8.066 ± 0.107
11.501AlaVal: 11.501 ± 0.114
2.073AlaTrp: 2.073 ± 0.039
2.543AlaTyr: 2.543 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.796CysAla: 0.796 ± 0.026
0.093CysCys: 0.093 ± 0.008
0.494CysAsp: 0.494 ± 0.021
0.358CysGlu: 0.358 ± 0.015
0.223CysPhe: 0.223 ± 0.013
0.838CysGly: 0.838 ± 0.027
0.183CysHis: 0.183 ± 0.012
0.194CysIle: 0.194 ± 0.012
0.106CysLys: 0.106 ± 0.008
0.638CysLeu: 0.638 ± 0.023
0.111CysMet: 0.111 ± 0.009
0.14CysAsn: 0.14 ± 0.011
0.444CysPro: 0.444 ± 0.019
0.16CysGln: 0.16 ± 0.011
0.54CysArg: 0.54 ± 0.022
0.469CysSer: 0.469 ± 0.019
0.466CysThr: 0.466 ± 0.021
0.592CysVal: 0.592 ± 0.024
0.116CysTrp: 0.116 ± 0.011
0.128CysTyr: 0.128 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
8.232AspAla: 8.232 ± 0.085
0.342AspCys: 0.342 ± 0.016
5.068AspAsp: 5.068 ± 0.066
4.801AspGlu: 4.801 ± 0.06
1.817AspPhe: 1.817 ± 0.04
6.652AspGly: 6.652 ± 0.084
1.58AspHis: 1.58 ± 0.037
2.075AspIle: 2.075 ± 0.037
1.163AspLys: 1.163 ± 0.036
7.661AspLeu: 7.661 ± 0.085
0.892AspMet: 0.892 ± 0.026
1.166AspAsn: 1.166 ± 0.032
4.526AspPro: 4.526 ± 0.053
1.938AspGln: 1.938 ± 0.041
5.003AspArg: 5.003 ± 0.07
2.708AspSer: 2.708 ± 0.047
3.215AspThr: 3.215 ± 0.051
6.486AspVal: 6.486 ± 0.082
1.027AspTrp: 1.027 ± 0.032
1.277AspTyr: 1.277 ± 0.03
0.0AspXaa: 0.0 ± 0.0
Glu
6.992GluAla: 6.992 ± 0.09
0.345GluCys: 0.345 ± 0.017
3.205GluAsp: 3.205 ± 0.055
3.136GluGlu: 3.136 ± 0.06
1.464GluPhe: 1.464 ± 0.036
4.182GluGly: 4.182 ± 0.055
1.678GluHis: 1.678 ± 0.038
2.441GluIle: 2.441 ± 0.042
1.344GluLys: 1.344 ± 0.039
6.267GluLeu: 6.267 ± 0.077
1.048GluMet: 1.048 ± 0.029
0.84GluAsn: 0.84 ± 0.025
3.164GluPro: 3.164 ± 0.055
2.285GluGln: 2.285 ± 0.041
4.973GluArg: 4.973 ± 0.067
2.918GluSer: 2.918 ± 0.05
3.02GluThr: 3.02 ± 0.049
5.572GluVal: 5.572 ± 0.064
0.864GluTrp: 0.864 ± 0.027
0.786GluTyr: 0.786 ± 0.025
0.0GluXaa: 0.0 ± 0.0
Phe
3.778PheAla: 3.778 ± 0.058
0.249PheCys: 0.249 ± 0.015
2.171PheAsp: 2.171 ± 0.038
1.645PheGlu: 1.645 ± 0.037
0.958PhePhe: 0.958 ± 0.028
2.968PheGly: 2.968 ± 0.051
0.631PheHis: 0.631 ± 0.023
0.863PheIle: 0.863 ± 0.026
0.521PheLys: 0.521 ± 0.019
2.636PheLeu: 2.636 ± 0.051
0.454PheMet: 0.454 ± 0.019
0.594PheAsn: 0.594 ± 0.02
1.277PhePro: 1.277 ± 0.031
0.61PheGln: 0.61 ± 0.021
1.709PheArg: 1.709 ± 0.039
1.571PheSer: 1.571 ± 0.034
2.016PheThr: 2.016 ± 0.043
2.7PheVal: 2.7 ± 0.05
0.44PheTrp: 0.44 ± 0.021
0.603PheTyr: 0.603 ± 0.024
0.0PheXaa: 0.0 ± 0.0
Gly
10.221GlyAla: 10.221 ± 0.098
0.789GlyCys: 0.789 ± 0.025
5.832GlyAsp: 5.832 ± 0.075
5.106GlyGlu: 5.106 ± 0.06
3.012GlyPhe: 3.012 ± 0.06
7.888GlyGly: 7.888 ± 0.089
2.107GlyHis: 2.107 ± 0.045
3.693GlyIle: 3.693 ± 0.055
2.106GlyLys: 2.106 ± 0.043
9.367GlyLeu: 9.367 ± 0.096
1.904GlyMet: 1.904 ± 0.04
1.745GlyAsn: 1.745 ± 0.058
4.311GlyPro: 4.311 ± 0.071
2.591GlyGln: 2.591 ± 0.043
7.045GlyArg: 7.045 ± 0.08
5.569GlySer: 5.569 ± 0.069
5.84GlyThr: 5.84 ± 0.084
8.011GlyVal: 8.011 ± 0.078
1.771GlyTrp: 1.771 ± 0.039
2.087GlyTyr: 2.087 ± 0.039
0.0GlyXaa: 0.0 ± 0.0
His
2.663HisAla: 2.663 ± 0.057
0.171HisCys: 0.171 ± 0.011
1.676HisAsp: 1.676 ± 0.04
1.295HisGlu: 1.295 ± 0.035
0.6HisPhe: 0.6 ± 0.023
2.12HisGly: 2.12 ± 0.048
0.693HisHis: 0.693 ± 0.025
0.551HisIle: 0.551 ± 0.02
0.315HisLys: 0.315 ± 0.017
2.42HisLeu: 2.42 ± 0.049
0.307HisMet: 0.307 ± 0.015
0.348HisAsn: 0.348 ± 0.017
1.599HisPro: 1.599 ± 0.04
0.657HisGln: 0.657 ± 0.023
1.802HisArg: 1.802 ± 0.041
0.855HisSer: 0.855 ± 0.027
1.091HisThr: 1.091 ± 0.027
2.092HisVal: 2.092 ± 0.045
0.349HisTrp: 0.349 ± 0.017
0.452HisTyr: 0.452 ± 0.016
0.0HisXaa: 0.0 ± 0.0
Ile
5.172IleAla: 5.172 ± 0.064
0.301IleCys: 0.301 ± 0.016
2.915IleAsp: 2.915 ± 0.049
2.424IleGlu: 2.424 ± 0.046
0.84IlePhe: 0.84 ± 0.023
3.915IleGly: 3.915 ± 0.076
0.644IleHis: 0.644 ± 0.019
1.074IleIle: 1.074 ± 0.03
0.82IleLys: 0.82 ± 0.026
2.582IleLeu: 2.582 ± 0.047
0.463IleMet: 0.463 ± 0.018
0.838IleAsn: 0.838 ± 0.025
1.775IlePro: 1.775 ± 0.039
0.74IleGln: 0.74 ± 0.026
2.217IleArg: 2.217 ± 0.037
1.974IleSer: 1.974 ± 0.034
2.461IleThr: 2.461 ± 0.052
3.313IleVal: 3.313 ± 0.051
0.439IleTrp: 0.439 ± 0.018
0.595IleTyr: 0.595 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
2.614LysAla: 2.614 ± 0.057
0.111LysCys: 0.111 ± 0.009
1.231LysAsp: 1.231 ± 0.032
0.954LysGlu: 0.954 ± 0.03
0.488LysPhe: 0.488 ± 0.02
1.58LysGly: 1.58 ± 0.039
0.402LysHis: 0.402 ± 0.018
0.863LysIle: 0.863 ± 0.028
0.791LysLys: 0.791 ± 0.038
1.744LysLeu: 1.744 ± 0.047
0.373LysMet: 0.373 ± 0.018
0.436LysAsn: 0.436 ± 0.02
1.173LysPro: 1.173 ± 0.036
0.668LysGln: 0.668 ± 0.024
1.329LysArg: 1.329 ± 0.031
1.064LysSer: 1.064 ± 0.026
1.265LysThr: 1.265 ± 0.037
1.99LysVal: 1.99 ± 0.049
0.223LysTrp: 0.223 ± 0.013
0.409LysTyr: 0.409 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
14.998LeuAla: 14.998 ± 0.144
0.649LeuCys: 0.649 ± 0.021
7.337LeuAsp: 7.337 ± 0.076
5.363LeuGlu: 5.363 ± 0.075
2.44LeuPhe: 2.44 ± 0.048
9.604LeuGly: 9.604 ± 0.099
2.058LeuHis: 2.058 ± 0.043
2.925LeuIle: 2.925 ± 0.056
1.741LeuLys: 1.741 ± 0.043
10.334LeuLeu: 10.334 ± 0.126
1.723LeuMet: 1.723 ± 0.037
1.597LeuAsn: 1.597 ± 0.037
5.637LeuPro: 5.637 ± 0.066
2.169LeuGln: 2.169 ± 0.044
7.469LeuArg: 7.469 ± 0.095
5.34LeuSer: 5.34 ± 0.067
6.462LeuThr: 6.462 ± 0.088
10.781LeuVal: 10.781 ± 0.111
1.205LeuTrp: 1.205 ± 0.03
1.432LeuTyr: 1.432 ± 0.029
0.0LeuXaa: 0.0 ± 0.0
Met
2.4MetAla: 2.4 ± 0.038
0.15MetCys: 0.15 ± 0.011
0.951MetAsp: 0.951 ± 0.027
0.789MetGlu: 0.789 ± 0.026
0.548MetPhe: 0.548 ± 0.022
1.462MetGly: 1.462 ± 0.037
0.385MetHis: 0.385 ± 0.017
0.69MetIle: 0.69 ± 0.022
0.472MetLys: 0.472 ± 0.02
1.822MetLeu: 1.822 ± 0.041
0.36MetMet: 0.36 ± 0.017
0.398MetAsn: 0.398 ± 0.016
1.095MetPro: 1.095 ± 0.028
0.483MetGln: 0.483 ± 0.016
1.516MetArg: 1.516 ± 0.034
1.465MetSer: 1.465 ± 0.031
1.787MetThr: 1.787 ± 0.037
1.583MetVal: 1.583 ± 0.03
0.223MetTrp: 0.223 ± 0.013
0.282MetTyr: 0.282 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.25AsnAla: 2.25 ± 0.049
0.14AsnCys: 0.14 ± 0.01
1.118AsnAsp: 1.118 ± 0.034
0.899AsnGlu: 0.899 ± 0.026
0.51AsnPhe: 0.51 ± 0.019
1.767AsnGly: 1.767 ± 0.049
0.372AsnHis: 0.372 ± 0.019
0.721AsnIle: 0.721 ± 0.026
0.397AsnLys: 0.397 ± 0.019
1.776AsnLeu: 1.776 ± 0.039
0.298AsnMet: 0.298 ± 0.016
0.469AsnAsn: 0.469 ± 0.034
1.342AsnPro: 1.342 ± 0.035
0.508AsnGln: 0.508 ± 0.021
1.222AsnArg: 1.222 ± 0.029
0.812AsnSer: 0.812 ± 0.025
1.075AsnThr: 1.075 ± 0.04
1.515AsnVal: 1.515 ± 0.037
0.247AsnTrp: 0.247 ± 0.014
0.407AsnTyr: 0.407 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
7.225ProAla: 7.225 ± 0.101
0.298ProCys: 0.298 ± 0.02
4.666ProAsp: 4.666 ± 0.072
3.68ProGlu: 3.68 ± 0.05
1.455ProPhe: 1.455 ± 0.033
5.456ProGly: 5.456 ± 0.069
1.164ProHis: 1.164 ± 0.033
1.735ProIle: 1.735 ± 0.036
0.946ProLys: 0.946 ± 0.03
4.643ProLeu: 4.643 ± 0.065
1.058ProMet: 1.058 ± 0.028
0.836ProAsn: 0.836 ± 0.029
2.662ProPro: 2.662 ± 0.052
1.355ProGln: 1.355 ± 0.035
3.533ProArg: 3.533 ± 0.064
3.227ProSer: 3.227 ± 0.054
3.948ProThr: 3.948 ± 0.064
5.154ProVal: 5.154 ± 0.063
0.925ProTrp: 0.925 ± 0.026
1.131ProTyr: 1.131 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
3.488GlnAla: 3.488 ± 0.043
0.155GlnCys: 0.155 ± 0.01
1.337GlnAsp: 1.337 ± 0.032
1.273GlnGlu: 1.273 ± 0.034
0.72GlnPhe: 0.72 ± 0.022
2.112GlnGly: 2.112 ± 0.035
0.692GlnHis: 0.692 ± 0.021
0.993GlnIle: 0.993 ± 0.025
0.54GlnLys: 0.54 ± 0.021
2.943GlnLeu: 2.943 ± 0.048
0.559GlnMet: 0.559 ± 0.021
0.418GlnAsn: 0.418 ± 0.02
1.574GlnPro: 1.574 ± 0.035
1.108GlnGln: 1.108 ± 0.034
2.434GlnArg: 2.434 ± 0.045
1.28GlnSer: 1.28 ± 0.03
1.43GlnThr: 1.43 ± 0.032
2.832GlnVal: 2.832 ± 0.047
0.467GlnTrp: 0.467 ± 0.018
0.433GlnTyr: 0.433 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
8.743ArgAla: 8.743 ± 0.101
0.493ArgCys: 0.493 ± 0.019
4.727ArgAsp: 4.727 ± 0.058
4.313ArgGlu: 4.313 ± 0.057
2.222ArgPhe: 2.222 ± 0.04
5.538ArgGly: 5.538 ± 0.071
1.856ArgHis: 1.856 ± 0.039
3.133ArgIle: 3.133 ± 0.045
1.386ArgLys: 1.386 ± 0.036
7.972ArgLeu: 7.972 ± 0.08
1.703ArgMet: 1.703 ± 0.035
1.31ArgAsn: 1.31 ± 0.031
4.146ArgPro: 4.146 ± 0.068
2.055ArgGln: 2.055 ± 0.041
7.074ArgArg: 7.074 ± 0.105
4.393ArgSer: 4.393 ± 0.061
4.611ArgThr: 4.611 ± 0.06
6.154ArgVal: 6.154 ± 0.07
1.345ArgTrp: 1.345 ± 0.033
1.441ArgTyr: 1.441 ± 0.033
0.0ArgXaa: 0.0 ± 0.0
Ser
6.689SerAla: 6.689 ± 0.067
0.387SerCys: 0.387 ± 0.017
3.257SerAsp: 3.257 ± 0.052
2.687SerGlu: 2.687 ± 0.048
1.814SerPhe: 1.814 ± 0.045
5.783SerGly: 5.783 ± 0.069
1.104SerHis: 1.104 ± 0.029
2.024SerIle: 2.024 ± 0.041
0.96SerLys: 0.96 ± 0.031
5.338SerLeu: 5.338 ± 0.067
1.35SerMet: 1.35 ± 0.033
0.964SerAsn: 0.964 ± 0.027
3.182SerPro: 3.182 ± 0.06
1.404SerGln: 1.404 ± 0.032
3.856SerArg: 3.856 ± 0.058
3.466SerSer: 3.466 ± 0.064
3.897SerThr: 3.897 ± 0.066
4.828SerVal: 4.828 ± 0.068
0.941SerTrp: 0.941 ± 0.03
1.281SerTyr: 1.281 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
7.602ThrAla: 7.602 ± 0.106
0.475ThrCys: 0.475 ± 0.027
3.969ThrAsp: 3.969 ± 0.064
3.029ThrGlu: 3.029 ± 0.047
1.979ThrPhe: 1.979 ± 0.041
6.171ThrGly: 6.171 ± 0.095
1.251ThrHis: 1.251 ± 0.029
2.528ThrIle: 2.528 ± 0.053
1.237ThrLys: 1.237 ± 0.037
5.932ThrLeu: 5.932 ± 0.065
1.175ThrMet: 1.175 ± 0.033
1.23ThrAsn: 1.23 ± 0.045
4.208ThrPro: 4.208 ± 0.07
1.531ThrGln: 1.531 ± 0.033
4.112ThrArg: 4.112 ± 0.061
4.022ThrSer: 4.022 ± 0.062
4.656ThrThr: 4.656 ± 0.081
5.827ThrVal: 5.827 ± 0.093
1.136ThrTrp: 1.136 ± 0.033
1.522ThrTyr: 1.522 ± 0.037
0.0ThrXaa: 0.0 ± 0.0
Val
12.588ValAla: 12.588 ± 0.115
0.683ValCys: 0.683 ± 0.022
6.442ValAsp: 6.442 ± 0.07
5.61ValGlu: 5.61 ± 0.074
2.551ValPhe: 2.551 ± 0.049
7.884ValGly: 7.884 ± 0.083
1.98ValHis: 1.98 ± 0.048
3.2ValIle: 3.2 ± 0.048
1.68ValLys: 1.68 ± 0.043
10.187ValLeu: 10.187 ± 0.113
1.688ValMet: 1.688 ± 0.039
1.67ValAsn: 1.67 ± 0.042
5.091ValPro: 5.091 ± 0.065
2.085ValGln: 2.085 ± 0.039
6.806ValArg: 6.806 ± 0.068
5.128ValSer: 5.128 ± 0.061
6.153ValThr: 6.153 ± 0.108
10.742ValVal: 10.742 ± 0.119
1.211ValTrp: 1.211 ± 0.033
1.398ValTyr: 1.398 ± 0.036
0.0ValXaa: 0.0 ± 0.0
Trp
1.614TrpAla: 1.614 ± 0.04
0.153TrpCys: 0.153 ± 0.011
0.938TrpAsp: 0.938 ± 0.03
0.707TrpGlu: 0.707 ± 0.021
0.572TrpPhe: 0.572 ± 0.024
1.073TrpGly: 1.073 ± 0.03
0.39TrpHis: 0.39 ± 0.017
0.58TrpIle: 0.58 ± 0.021
0.301TrpLys: 0.301 ± 0.016
1.893TrpLeu: 1.893 ± 0.042
0.322TrpMet: 0.322 ± 0.017
0.35TrpAsn: 0.35 ± 0.018
0.785TrpPro: 0.785 ± 0.027
0.563TrpGln: 0.563 ± 0.018
1.324TrpArg: 1.324 ± 0.029
1.115TrpSer: 1.115 ± 0.029
1.111TrpThr: 1.111 ± 0.03
1.274TrpVal: 1.274 ± 0.03
0.414TrpTrp: 0.414 ± 0.018
0.262TrpTyr: 0.262 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.576TyrAla: 2.576 ± 0.042
0.14TyrCys: 0.14 ± 0.009
1.641TyrAsp: 1.641 ± 0.036
0.956TyrGlu: 0.956 ± 0.027
0.622TyrPhe: 0.622 ± 0.022
1.844TyrGly: 1.844 ± 0.035
0.308TyrHis: 0.308 ± 0.014
0.489TyrIle: 0.489 ± 0.022
0.374TyrLys: 0.374 ± 0.021
1.955TyrLeu: 1.955 ± 0.038
0.22TyrMet: 0.22 ± 0.014
0.372TyrAsn: 0.372 ± 0.018
0.945TyrPro: 0.945 ± 0.029
0.487TyrGln: 0.487 ± 0.02
1.381TyrArg: 1.381 ± 0.039
0.983TyrSer: 0.983 ± 0.027
1.019TyrThr: 1.019 ± 0.029
1.827TyrVal: 1.827 ± 0.037
0.325TyrTrp: 0.325 ± 0.017
0.416TyrTyr: 0.416 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4242 proteins (1384144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski