Amino acid dipepetide frequency for Jaminaea rosea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.254AlaAla: 16.254 ± 0.113	0.976AlaCys: 0.976 ± 0.016	4.805AlaAsp: 4.805 ± 0.045	5.934AlaGlu: 5.934 ± 0.061	2.985AlaPhe: 2.985 ± 0.034	8.867AlaGly: 8.867 ± 0.061	2.288AlaHis: 2.288 ± 0.024	3.749AlaIle: 3.749 ± 0.037	4.81AlaLys: 4.81 ± 0.051	9.034AlaLeu: 9.034 ± 0.068	2.247AlaMet: 2.247 ± 0.027	2.968AlaAsn: 2.968 ± 0.033	6.823AlaPro: 6.823 ± 0.059	4.555AlaGln: 4.555 ± 0.041	6.951AlaArg: 6.951 ± 0.05	11.676AlaSer: 11.676 ± 0.077	6.812AlaThr: 6.812 ± 0.049	5.702AlaVal: 5.702 ± 0.05	1.314AlaTrp: 1.314 ± 0.022	1.967AlaTyr: 1.967 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.877CysAla: 0.877 ± 0.017	0.198CysCys: 0.198 ± 0.008	0.538CysAsp: 0.538 ± 0.014	0.524CysGlu: 0.524 ± 0.013	0.416CysPhe: 0.416 ± 0.011	0.799CysGly: 0.799 ± 0.018	0.264CysHis: 0.264 ± 0.011	0.469CysIle: 0.469 ± 0.011	0.398CysLys: 0.398 ± 0.013	1.113CysLeu: 1.113 ± 0.02	0.171CysMet: 0.171 ± 0.007	0.309CysAsn: 0.309 ± 0.01	0.61CysPro: 0.61 ± 0.015	0.348CysGln: 0.348 ± 0.01	0.673CysArg: 0.673 ± 0.014	0.863CysSer: 0.863 ± 0.018	0.563CysThr: 0.563 ± 0.014	0.659CysVal: 0.659 ± 0.012	0.156CysTrp: 0.156 ± 0.007	0.274CysTyr: 0.274 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.792AspAla: 5.792 ± 0.045	0.505AspCys: 0.505 ± 0.013	5.279AspAsp: 5.279 ± 0.066	5.503AspGlu: 5.503 ± 0.052	1.753AspPhe: 1.753 ± 0.022	4.599AspGly: 4.599 ± 0.034	1.062AspHis: 1.062 ± 0.017	1.838AspIle: 1.838 ± 0.027	1.886AspLys: 1.886 ± 0.026	4.592AspLeu: 4.592 ± 0.037	0.907AspMet: 0.907 ± 0.014	1.247AspAsn: 1.247 ± 0.02	2.937AspPro: 2.937 ± 0.031	1.673AspGln: 1.673 ± 0.023	2.888AspArg: 2.888 ± 0.03	4.012AspSer: 4.012 ± 0.043	2.219AspThr: 2.219 ± 0.029	3.881AspVal: 3.881 ± 0.038	0.791AspTrp: 0.791 ± 0.015	1.178AspTyr: 1.178 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	7.055GluAla: 7.055 ± 0.056	0.5GluCys: 0.5 ± 0.013	4.515GluAsp: 4.515 ± 0.042	6.833GluGlu: 6.833 ± 0.081	1.13GluPhe: 1.13 ± 0.02	5.234GluGly: 5.234 ± 0.047	1.287GluHis: 1.287 ± 0.02	1.894GluIle: 1.894 ± 0.025	2.938GluLys: 2.938 ± 0.043	4.583GluLeu: 4.583 ± 0.046	1.434GluMet: 1.434 ± 0.023	1.285GluAsn: 1.285 ± 0.02	2.326GluPro: 2.326 ± 0.027	2.91GluGln: 2.91 ± 0.034	4.713GluArg: 4.713 ± 0.051	3.835GluSer: 3.835 ± 0.037	2.641GluThr: 2.641 ± 0.027	3.522GluVal: 3.522 ± 0.032	0.887GluTrp: 0.887 ± 0.017	1.163GluTyr: 1.163 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.052PheAla: 3.052 ± 0.03	0.41PheCys: 0.41 ± 0.011	1.881PheAsp: 1.881 ± 0.026	1.699PheGlu: 1.699 ± 0.024	1.211PhePhe: 1.211 ± 0.022	2.407PheGly: 2.407 ± 0.039	0.672PheHis: 0.672 ± 0.014	1.138PheIle: 1.138 ± 0.02	1.134PheLys: 1.134 ± 0.017	2.784PheLeu: 2.784 ± 0.03	0.503PheMet: 0.503 ± 0.012	0.947PheAsn: 0.947 ± 0.018	1.487PhePro: 1.487 ± 0.022	0.903PheGln: 0.903 ± 0.015	1.516PheArg: 1.516 ± 0.023	2.581PheSer: 2.581 ± 0.03	1.638PheThr: 1.638 ± 0.024	1.994PheVal: 1.994 ± 0.027	0.466PheTrp: 0.466 ± 0.013	0.761PheTyr: 0.761 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	8.115GlyAla: 8.115 ± 0.064	0.789GlyCys: 0.789 ± 0.015	4.174GlyAsp: 4.174 ± 0.037	4.985GlyGlu: 4.985 ± 0.045	2.291GlyPhe: 2.291 ± 0.028	9.85GlyGly: 9.85 ± 0.1	1.806GlyHis: 1.806 ± 0.025	2.73GlyIle: 2.73 ± 0.034	3.861GlyLys: 3.861 ± 0.039	6.051GlyLeu: 6.051 ± 0.054	1.704GlyMet: 1.704 ± 0.028	2.308GlyAsn: 2.308 ± 0.03	3.976GlyPro: 3.976 ± 0.045	3.318GlyGln: 3.318 ± 0.038	5.164GlyArg: 5.164 ± 0.043	7.994GlySer: 7.994 ± 0.067	3.944GlyThr: 3.944 ± 0.037	4.378GlyVal: 4.378 ± 0.041	1.175GlyTrp: 1.175 ± 0.019	1.749GlyTyr: 1.749 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	2.261HisAla: 2.261 ± 0.027	0.295HisCys: 0.295 ± 0.009	1.282HisAsp: 1.282 ± 0.02	1.163HisGlu: 1.163 ± 0.017	0.832HisPhe: 0.832 ± 0.014	1.706HisGly: 1.706 ± 0.027	1.155HisHis: 1.155 ± 0.029	0.88HisIle: 0.88 ± 0.015	0.716HisLys: 0.716 ± 0.015	2.48HisLeu: 2.48 ± 0.025	0.352HisMet: 0.352 ± 0.01	0.596HisAsn: 0.596 ± 0.013	1.766HisPro: 1.766 ± 0.025	1.09HisGln: 1.09 ± 0.024	1.73HisArg: 1.73 ± 0.023	2.04HisSer: 2.04 ± 0.028	1.098HisThr: 1.098 ± 0.018	1.261HisVal: 1.261 ± 0.022	0.299HisTrp: 0.299 ± 0.01	0.58HisTyr: 0.58 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.743IleAla: 3.743 ± 0.035	0.465IleCys: 0.465 ± 0.01	2.316IleAsp: 2.316 ± 0.027	2.211IleGlu: 2.211 ± 0.027	1.249IlePhe: 1.249 ± 0.023	2.41IleGly: 2.41 ± 0.031	0.814IleHis: 0.814 ± 0.016	1.449IleIle: 1.449 ± 0.022	1.63IleLys: 1.63 ± 0.025	3.291IleLeu: 3.291 ± 0.036	0.617IleMet: 0.617 ± 0.013	1.15IleAsn: 1.15 ± 0.018	2.028IlePro: 2.028 ± 0.023	1.189IleGln: 1.189 ± 0.021	2.09IleArg: 2.09 ± 0.025	2.837IleSer: 2.837 ± 0.025	1.824IleThr: 1.824 ± 0.025	2.521IleVal: 2.521 ± 0.03	0.491IleTrp: 0.491 ± 0.014	0.858IleTyr: 0.858 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.78LysAla: 4.78 ± 0.049	0.338LysCys: 0.338 ± 0.011	2.183LysAsp: 2.183 ± 0.03	3.141LysGlu: 3.141 ± 0.039	0.809LysPhe: 0.809 ± 0.015	3.477LysGly: 3.477 ± 0.04	0.888LysHis: 0.888 ± 0.017	1.387LysIle: 1.387 ± 0.022	2.839LysLys: 2.839 ± 0.043	3.308LysLeu: 3.308 ± 0.035	0.904LysMet: 0.904 ± 0.016	1.009LysAsn: 1.009 ± 0.019	2.262LysPro: 2.262 ± 0.028	1.756LysGln: 1.756 ± 0.026	3.617LysArg: 3.617 ± 0.037	2.993LysSer: 2.993 ± 0.035	2.219LysThr: 2.219 ± 0.029	2.505LysVal: 2.505 ± 0.033	0.529LysTrp: 0.529 ± 0.013	0.805LysTyr: 0.805 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	9.459LeuAla: 9.459 ± 0.062	1.131LeuCys: 1.131 ± 0.019	4.908LeuAsp: 4.908 ± 0.044	4.768LeuGlu: 4.768 ± 0.047	2.926LeuPhe: 2.926 ± 0.033	5.941LeuGly: 5.941 ± 0.051	2.076LeuHis: 2.076 ± 0.028	3.138LeuIle: 3.138 ± 0.034	3.306LeuLys: 3.306 ± 0.035	8.849LeuLeu: 8.849 ± 0.073	1.442LeuMet: 1.442 ± 0.021	2.487LeuAsn: 2.487 ± 0.028	6.164LeuPro: 6.164 ± 0.045	3.372LeuGln: 3.372 ± 0.032	6.384LeuArg: 6.384 ± 0.041	7.832LeuSer: 7.832 ± 0.055	4.527LeuThr: 4.527 ± 0.039	5.326LeuVal: 5.326 ± 0.051	1.032LeuTrp: 1.032 ± 0.018	1.893LeuTyr: 1.893 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.305MetAla: 2.305 ± 0.026	0.185MetCys: 0.185 ± 0.007	1.063MetAsp: 1.063 ± 0.018	1.027MetGlu: 1.027 ± 0.017	0.411MetPhe: 0.411 ± 0.012	1.538MetGly: 1.538 ± 0.022	0.38MetHis: 0.38 ± 0.011	0.642MetIle: 0.642 ± 0.014	0.694MetLys: 0.694 ± 0.014	1.683MetLeu: 1.683 ± 0.02	0.49MetMet: 0.49 ± 0.013	0.485MetAsn: 0.485 ± 0.012	1.377MetPro: 1.377 ± 0.02	0.735MetGln: 0.735 ± 0.016	1.405MetArg: 1.405 ± 0.02	1.834MetSer: 1.834 ± 0.024	1.158MetThr: 1.158 ± 0.019	1.013MetVal: 1.013 ± 0.018	0.208MetTrp: 0.208 ± 0.007	0.333MetTyr: 0.333 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.102AsnAla: 3.102 ± 0.031	0.277AsnCys: 0.277 ± 0.009	1.559AsnAsp: 1.559 ± 0.021	1.569AsnGlu: 1.569 ± 0.022	0.889AsnPhe: 0.889 ± 0.015	2.838AsnGly: 2.838 ± 0.034	0.591AsnHis: 0.591 ± 0.014	1.072AsnIle: 1.072 ± 0.019	1.104AsnLys: 1.104 ± 0.017	2.337AsnLeu: 2.337 ± 0.025	0.469AsnMet: 0.469 ± 0.011	0.933AsnAsn: 0.933 ± 0.02	1.635AsnPro: 1.635 ± 0.023	0.884AsnGln: 0.884 ± 0.016	1.55AsnArg: 1.55 ± 0.019	2.15AsnSer: 2.15 ± 0.028	1.407AsnThr: 1.407 ± 0.021	1.861AsnVal: 1.861 ± 0.021	0.354AsnTrp: 0.354 ± 0.01	0.611AsnTyr: 0.611 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.242ProAla: 7.242 ± 0.067	0.504ProCys: 0.504 ± 0.013	2.54ProAsp: 2.54 ± 0.031	2.802ProGlu: 2.802 ± 0.029	1.866ProPhe: 1.866 ± 0.024	4.054ProGly: 4.054 ± 0.044	1.592ProHis: 1.592 ± 0.024	2.09ProIle: 2.09 ± 0.028	2.04ProLys: 2.04 ± 0.027	5.378ProLeu: 5.378 ± 0.04	0.978ProMet: 0.978 ± 0.019	1.632ProAsn: 1.632 ± 0.023	6.933ProPro: 6.933 ± 0.084	2.607ProGln: 2.607 ± 0.036	4.163ProArg: 4.163 ± 0.044	8.416ProSer: 8.416 ± 0.073	4.37ProThr: 4.37 ± 0.043	3.048ProVal: 3.048 ± 0.03	0.676ProTrp: 0.676 ± 0.015	1.266ProTyr: 1.266 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.523GlnAla: 4.523 ± 0.046	0.347GlnCys: 0.347 ± 0.01	1.977GlnAsp: 1.977 ± 0.023	2.409GlnGlu: 2.409 ± 0.029	0.816GlnPhe: 0.816 ± 0.016	3.163GlnGly: 3.163 ± 0.031	1.348GlnHis: 1.348 ± 0.028	1.23GlnIle: 1.23 ± 0.021	1.382GlnLys: 1.382 ± 0.02	3.441GlnLeu: 3.441 ± 0.038	0.815GlnMet: 0.815 ± 0.015	0.886GlnAsn: 0.886 ± 0.017	2.951GlnPro: 2.951 ± 0.044	4.183GlnGln: 4.183 ± 0.107	3.604GlnArg: 3.604 ± 0.042	3.264GlnSer: 3.264 ± 0.035	1.914GlnThr: 1.914 ± 0.025	2.06GlnVal: 2.06 ± 0.023	0.508GlnTrp: 0.508 ± 0.011	0.798GlnTyr: 0.798 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	6.384ArgAla: 6.384 ± 0.046	0.785ArgCys: 0.785 ± 0.018	3.509ArgAsp: 3.509 ± 0.037	4.387ArgGlu: 4.387 ± 0.04	2.032ArgPhe: 2.032 ± 0.023	5.157ArgGly: 5.157 ± 0.05	1.699ArgHis: 1.699 ± 0.021	2.515ArgIle: 2.515 ± 0.026	3.402ArgLys: 3.402 ± 0.032	6.178ArgLeu: 6.178 ± 0.049	1.349ArgMet: 1.349 ± 0.021	1.913ArgAsn: 1.913 ± 0.025	4.286ArgPro: 4.286 ± 0.041	3.032ArgGln: 3.032 ± 0.036	7.06ArgArg: 7.06 ± 0.069	6.275ArgSer: 6.275 ± 0.061	3.378ArgThr: 3.378 ± 0.03	3.476ArgVal: 3.476 ± 0.03	0.946ArgTrp: 0.946 ± 0.017	1.463ArgTyr: 1.463 ± 0.024	0.0ArgXaa: 0.0 ± 0.0
Ser	10.207SerAla: 10.207 ± 0.062	0.803SerCys: 0.803 ± 0.018	4.204SerAsp: 4.204 ± 0.043	3.872SerGlu: 3.872 ± 0.034	2.761SerPhe: 2.761 ± 0.029	7.292SerGly: 7.292 ± 0.063	2.27SerHis: 2.27 ± 0.03	3.374SerIle: 3.374 ± 0.03	3.601SerLys: 3.601 ± 0.036	8.188SerLeu: 8.188 ± 0.058	1.775SerMet: 1.775 ± 0.023	2.812SerAsn: 2.812 ± 0.028	6.978SerPro: 6.978 ± 0.086	3.585SerGln: 3.585 ± 0.034	6.222SerArg: 6.222 ± 0.052	17.159SerSer: 17.159 ± 0.169	6.91SerThr: 6.91 ± 0.063	4.443SerVal: 4.443 ± 0.041	1.044SerTrp: 1.044 ± 0.02	1.826SerTyr: 1.826 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	6.209ThrAla: 6.209 ± 0.049	0.545ThrCys: 0.545 ± 0.013	2.22ThrAsp: 2.22 ± 0.026	2.219ThrGlu: 2.219 ± 0.025	1.774ThrPhe: 1.774 ± 0.025	4.043ThrGly: 4.043 ± 0.038	1.214ThrHis: 1.214 ± 0.021	2.155ThrIle: 2.155 ± 0.028	2.052ThrLys: 2.052 ± 0.023	5.18ThrLeu: 5.18 ± 0.045	1.098ThrMet: 1.098 ± 0.02	1.511ThrAsn: 1.511 ± 0.021	4.599ThrPro: 4.599 ± 0.049	1.933ThrGln: 1.933 ± 0.024	3.329ThrArg: 3.329 ± 0.032	6.658ThrSer: 6.658 ± 0.062	4.38ThrThr: 4.38 ± 0.056	2.951ThrVal: 2.951 ± 0.035	0.677ThrTrp: 0.677 ± 0.016	1.127ThrTyr: 1.127 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	6.171ValAla: 6.171 ± 0.047	0.682ValCys: 0.682 ± 0.015	3.511ValAsp: 3.511 ± 0.034	3.712ValGlu: 3.712 ± 0.034	1.844ValPhe: 1.844 ± 0.027	4.348ValGly: 4.348 ± 0.037	1.259ValHis: 1.259 ± 0.022	2.084ValIle: 2.084 ± 0.029	2.629ValLys: 2.629 ± 0.03	5.127ValLeu: 5.127 ± 0.046	1.059ValMet: 1.059 ± 0.017	1.642ValAsn: 1.642 ± 0.023	3.342ValPro: 3.342 ± 0.033	2.155ValGln: 2.155 ± 0.026	3.751ValArg: 3.751 ± 0.039	4.199ValSer: 4.199 ± 0.035	2.982ValThr: 2.982 ± 0.029	4.061ValVal: 4.061 ± 0.042	0.788ValTrp: 0.788 ± 0.016	1.283ValTyr: 1.283 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.159TrpAla: 1.159 ± 0.018	0.189TrpCys: 0.189 ± 0.007	0.741TrpAsp: 0.741 ± 0.017	0.746TrpGlu: 0.746 ± 0.015	0.407TrpPhe: 0.407 ± 0.012	0.869TrpGly: 0.869 ± 0.018	0.326TrpHis: 0.326 ± 0.009	0.521TrpIle: 0.521 ± 0.013	0.578TrpLys: 0.578 ± 0.014	1.296TrpLeu: 1.296 ± 0.021	0.29TrpMet: 0.29 ± 0.009	0.409TrpAsn: 0.409 ± 0.011	0.632TrpPro: 0.632 ± 0.014	0.591TrpGln: 0.591 ± 0.014	1.022TrpArg: 1.022 ± 0.017	1.093TrpSer: 1.093 ± 0.018	0.785TrpThr: 0.785 ± 0.016	0.699TrpVal: 0.699 ± 0.014	0.263TrpTrp: 0.263 ± 0.01	0.308TrpTyr: 0.308 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.029TyrAla: 2.029 ± 0.029	0.298TyrCys: 0.298 ± 0.01	1.337TyrAsp: 1.337 ± 0.02	1.181TyrGlu: 1.181 ± 0.019	0.782TyrPhe: 0.782 ± 0.015	1.769TyrGly: 1.769 ± 0.029	0.59TyrHis: 0.59 ± 0.015	0.829TyrIle: 0.829 ± 0.016	0.751TyrLys: 0.751 ± 0.016	2.066TyrLeu: 2.066 ± 0.021	0.361TyrMet: 0.361 ± 0.011	0.664TyrAsn: 0.664 ± 0.016	1.085TyrPro: 1.085 ± 0.019	0.799TyrGln: 0.799 ± 0.014	1.394TyrArg: 1.394 ± 0.022	1.616TyrSer: 1.616 ± 0.022	1.106TyrThr: 1.106 ± 0.02	1.266TyrVal: 1.266 ± 0.021	0.318TyrTrp: 0.318 ± 0.009	0.624TyrTyr: 0.624 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 6858 proteins (3700262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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