Apple rubbery wood virus 2

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Ellioviricetes; Bunyavirales; Phenuiviridae; Rubodvirus; Apple rubodvirus 2

Average proteome isoelectric point is 7.0

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A2S1B5C1|A0A2S1B5C1_9VIRU Isoform of A0A2S1B5H3 Nucleocapsid protein OS=Apple rubbery wood virus 2 OX=2164103 GN=CP PE=4 SV=1
MM1 pKa = 7.36SASIMQRR8 pKa = 11.84IDD10 pKa = 3.45LEE12 pKa = 4.48NVCDD16 pKa = 3.8LTYY19 pKa = 11.01EE20 pKa = 4.62GVFSSDD26 pKa = 2.83MPINIEE32 pKa = 4.04YY33 pKa = 9.76VHH35 pKa = 6.75EE36 pKa = 4.56GNYY39 pKa = 8.84IRR41 pKa = 11.84LMNKK45 pKa = 8.7NLEE48 pKa = 4.08YY49 pKa = 10.75EE50 pKa = 4.48LIKK53 pKa = 10.05IDD55 pKa = 3.81YY56 pKa = 8.78NNPNFIHH63 pKa = 7.28DD64 pKa = 4.15CVSYY68 pKa = 10.73AISGQFKK75 pKa = 10.27TDD77 pKa = 3.18MTSYY81 pKa = 11.34GLTPDD86 pKa = 4.2FVSEE90 pKa = 4.36DD91 pKa = 3.62FLLEE95 pKa = 3.79ISTSSVSDD103 pKa = 4.11FHH105 pKa = 8.64ALEE108 pKa = 4.04IQMQSKK114 pKa = 9.46LKK116 pKa = 10.38KK117 pKa = 8.97YY118 pKa = 10.32AHH120 pKa = 6.87IANGRR125 pKa = 11.84KK126 pKa = 9.85VIVIVISYY134 pKa = 10.58DD135 pKa = 3.62LVVSNYY141 pKa = 9.44EE142 pKa = 3.74IKK144 pKa = 10.92KK145 pKa = 8.5NIQMAMTSNFCILKK159 pKa = 10.02RR160 pKa = 11.84LQSEE164 pKa = 4.32LLMEE168 pKa = 5.08GKK170 pKa = 8.77TYY172 pKa = 7.58WTTSSEE178 pKa = 4.47TKK180 pKa = 10.63FSRR183 pKa = 11.84KK184 pKa = 9.62LSTILQNYY192 pKa = 7.19VPKK195 pKa = 10.66NHH197 pKa = 6.68YY198 pKa = 9.62DD199 pKa = 3.45GKK201 pKa = 10.7KK202 pKa = 9.63QAFDD206 pKa = 5.43LIDD209 pKa = 3.73QVWEE213 pKa = 3.91NFDD216 pKa = 3.7YY217 pKa = 10.97DD218 pKa = 3.75SSLGQVLTEE227 pKa = 4.14VVKK230 pKa = 10.83HH231 pKa = 5.72VEE233 pKa = 4.51DD234 pKa = 6.32DD235 pKa = 2.94ITTAKK240 pKa = 10.47FIEE243 pKa = 4.94KK244 pKa = 9.19PPSPISFPTEE254 pKa = 3.12GRR256 pKa = 11.84TDD258 pKa = 3.83LKK260 pKa = 10.64RR261 pKa = 11.84ITVIPMICPEE271 pKa = 4.1KK272 pKa = 10.37RR273 pKa = 11.84VSLEE277 pKa = 3.93LLEE280 pKa = 4.53TTCVNSLIAEE290 pKa = 4.27SKK292 pKa = 10.35IKK294 pKa = 10.23IIEE297 pKa = 4.19EE298 pKa = 3.95GKK300 pKa = 8.38ITQKK304 pKa = 8.65TQIDD308 pKa = 4.17FATPMTHH315 pKa = 6.58FEE317 pKa = 4.19IMSGYY322 pKa = 10.52YY323 pKa = 9.2EE324 pKa = 5.44DD325 pKa = 4.15KK326 pKa = 11.22RR327 pKa = 11.84EE328 pKa = 4.05DD329 pKa = 3.21KK330 pKa = 10.82KK331 pKa = 11.12EE332 pKa = 3.85RR333 pKa = 11.84KK334 pKa = 9.47GYY336 pKa = 7.49QFKK339 pKa = 11.01PEE341 pKa = 4.09LTPKK345 pKa = 10.55EE346 pKa = 4.07MLEE349 pKa = 4.22LNLDD353 pKa = 3.36GVMAKK358 pKa = 9.34EE359 pKa = 4.47FKK361 pKa = 10.58DD362 pKa = 3.09KK363 pKa = 11.36TEE365 pKa = 4.5IIEE368 pKa = 3.95KK369 pKa = 9.88RR370 pKa = 11.84QLSKK374 pKa = 10.87IPFSFNVDD382 pKa = 3.29TQDD385 pKa = 3.09IEE387 pKa = 4.53SFRR390 pKa = 11.84LEE392 pKa = 3.96FAKK395 pKa = 11.04LLDD398 pKa = 3.91EE399 pKa = 4.36KK400 pKa = 11.31VEE402 pKa = 4.24NVVEE406 pKa = 4.12DD407 pKa = 3.45QAYY410 pKa = 9.79GLMRR414 pKa = 11.84TAYY417 pKa = 10.25SCMIDD422 pKa = 3.13AHH424 pKa = 8.28VNMIDD429 pKa = 3.37QGEE432 pKa = 4.21NVIKK436 pKa = 10.19EE437 pKa = 4.29HH438 pKa = 7.07NEE440 pKa = 3.62EE441 pKa = 4.16NSTKK445 pKa = 10.39FINWLNFVSDD455 pKa = 4.94LMFEE459 pKa = 4.45INLSLRR465 pKa = 11.84EE466 pKa = 3.94NTKK469 pKa = 10.67NGFFIVKK476 pKa = 9.15SLKK479 pKa = 10.19RR480 pKa = 11.84FQADD484 pKa = 3.57VYY486 pKa = 11.14IKK488 pKa = 7.43TTNSNSHH495 pKa = 5.8IFFFVVCKK503 pKa = 10.62VNYY506 pKa = 9.56ILSDD510 pKa = 3.3TLGPKK515 pKa = 10.07FVTSNGILVTEE526 pKa = 4.89WGSLMKK532 pKa = 10.11RR533 pKa = 11.84DD534 pKa = 3.97LEE536 pKa = 4.26NFLSCKK542 pKa = 7.52EE543 pKa = 4.36TIRR546 pKa = 11.84STFCCYY552 pKa = 10.84DD553 pKa = 3.68EE554 pKa = 6.44IFDD557 pKa = 4.15KK558 pKa = 11.09CHH560 pKa = 6.84NSALTNAKK568 pKa = 8.87WLSLMIFLSNKK579 pKa = 9.32DD580 pKa = 3.57RR581 pKa = 11.84NEE583 pKa = 4.25EE584 pKa = 3.92IVTSLRR590 pKa = 11.84YY591 pKa = 8.27TYY593 pKa = 9.51MKK595 pKa = 10.09SLSITEE601 pKa = 4.75HH602 pKa = 6.39SSTMNKK608 pKa = 10.13KK609 pKa = 10.41LGLLMRR615 pKa = 11.84DD616 pKa = 3.16RR617 pKa = 11.84LQVYY621 pKa = 7.58LTNKK625 pKa = 9.71VYY627 pKa = 11.03LLNNFLTDD635 pKa = 3.29NKK637 pKa = 9.63PQVSFDD643 pKa = 3.25QGTLEE648 pKa = 3.95VHH650 pKa = 6.0GMKK653 pKa = 10.53DD654 pKa = 3.49LFGSDD659 pKa = 2.62ITFKK663 pKa = 10.9EE664 pKa = 4.9GINISYY670 pKa = 10.32AGYY673 pKa = 10.59IMTKK677 pKa = 10.01VKK679 pKa = 10.36QPQSNQSSKK688 pKa = 10.43MIEE691 pKa = 4.26KK692 pKa = 10.32ILDD695 pKa = 3.58YY696 pKa = 10.51EE697 pKa = 4.44IKK699 pKa = 10.23FLNVKK704 pKa = 10.46AEE706 pKa = 4.25EE707 pKa = 4.16ISTNEE712 pKa = 3.28LNIRR716 pKa = 11.84KK717 pKa = 8.63DD718 pKa = 2.94HH719 pKa = 6.33CFDD722 pKa = 3.35YY723 pKa = 10.79KK724 pKa = 10.21YY725 pKa = 11.29VRR727 pKa = 11.84TFSEE731 pKa = 4.1LGKK734 pKa = 10.44EE735 pKa = 4.04LLYY738 pKa = 11.34DD739 pKa = 3.46MFGNQLDD746 pKa = 4.0SIIRR750 pKa = 11.84EE751 pKa = 4.13RR752 pKa = 11.84ITSNLMSIDD761 pKa = 3.79FEE763 pKa = 5.24SIATLKK769 pKa = 11.01ASAKK773 pKa = 8.97PDD775 pKa = 3.35LRR777 pKa = 11.84GKK779 pKa = 10.53YY780 pKa = 9.67SEE782 pKa = 4.69EE783 pKa = 3.67NLEE786 pKa = 4.18EE787 pKa = 4.3LKK789 pKa = 10.73SARR792 pKa = 11.84PRR794 pKa = 11.84VMSNIVKK801 pKa = 10.45LINTYY806 pKa = 10.36KK807 pKa = 10.23PEE809 pKa = 4.02HH810 pKa = 6.61FIDD813 pKa = 4.22LVEE816 pKa = 4.12PCISYY821 pKa = 10.12IVNNNCFNVEE831 pKa = 4.66LFPKK835 pKa = 9.85DD836 pKa = 3.12QHH838 pKa = 6.23NGLRR842 pKa = 11.84EE843 pKa = 3.9IYY845 pKa = 10.54VVDD848 pKa = 2.98IHH850 pKa = 8.08ARR852 pKa = 11.84IVQLFVEE859 pKa = 5.23TISRR863 pKa = 11.84SLCSFFQSEE872 pKa = 4.59TLNHH876 pKa = 6.83PKK878 pKa = 10.51NSTALIPKK886 pKa = 6.53TLKK889 pKa = 10.76YY890 pKa = 10.63SLEE893 pKa = 4.28NNGSPFCLMKK903 pKa = 10.93SGDD906 pKa = 3.55ASKK909 pKa = 10.2WSQSQIVTKK918 pKa = 9.62FYY920 pKa = 10.73IVLKK924 pKa = 10.67AFLPQEE930 pKa = 3.65YY931 pKa = 10.21HH932 pKa = 7.21KK933 pKa = 10.51IVKK936 pKa = 9.87DD937 pKa = 3.96ALSLWFDD944 pKa = 3.64KK945 pKa = 11.05KK946 pKa = 10.79IFLPPSLIEE955 pKa = 4.56SFMGTNFHH963 pKa = 6.53TSNVVLNDD971 pKa = 3.24LRR973 pKa = 11.84EE974 pKa = 4.3GNLCAIKK981 pKa = 10.43KK982 pKa = 9.81KK983 pKa = 10.51EE984 pKa = 4.04DD985 pKa = 3.31MFMTIQSGFMQGILHH1000 pKa = 6.59HH1001 pKa = 6.7SSSLFHH1007 pKa = 6.72TIVQEE1012 pKa = 4.17GFRR1015 pKa = 11.84QIQFKK1020 pKa = 9.08VLRR1023 pKa = 11.84DD1024 pKa = 3.66AFNDD1028 pKa = 4.3TIYY1031 pKa = 10.67KK1032 pKa = 10.16QYY1034 pKa = 10.5FEE1036 pKa = 4.68KK1037 pKa = 11.29VNICVLQGSDD1047 pKa = 3.94DD1048 pKa = 3.83SSMAIMGDD1056 pKa = 2.86SKK1058 pKa = 11.11LFHH1061 pKa = 6.17KK1062 pKa = 10.37HH1063 pKa = 5.88KK1064 pKa = 10.66EE1065 pKa = 4.02LFLSLMHH1072 pKa = 6.89LKK1074 pKa = 10.76DD1075 pKa = 3.34SLSYY1079 pKa = 10.7KK1080 pKa = 10.48FGIIPSAEE1088 pKa = 3.94KK1089 pKa = 9.54TATCVPFIIEE1099 pKa = 4.74YY1100 pKa = 9.63NSQWLALGKK1109 pKa = 10.31SIQPTIKK1116 pKa = 9.81FAMVACQLPSAQSIIQRR1133 pKa = 11.84QEE1135 pKa = 3.29FYY1137 pKa = 11.6YY1138 pKa = 11.12NLLKK1142 pKa = 10.89DD1143 pKa = 4.22CLEE1146 pKa = 4.63KK1147 pKa = 11.21GCTTHH1152 pKa = 6.27TCFKK1156 pKa = 10.54IKK1158 pKa = 10.54LNQLCAYY1165 pKa = 9.84YY1166 pKa = 10.99NLLGCNNTSSFQVTSKK1182 pKa = 10.89LLKK1185 pKa = 9.74EE1186 pKa = 4.57CLNPSLGFFMLEE1198 pKa = 4.25PIVATAVFGFDD1209 pKa = 3.45FNFYY1213 pKa = 10.64CHH1215 pKa = 5.91TQGALVKK1222 pKa = 8.97YY1223 pKa = 10.0LPNSYY1228 pKa = 8.22HH1229 pKa = 6.42TPMEE1233 pKa = 4.37TNLPSGNTLRR1243 pKa = 11.84LNTHH1247 pKa = 6.13ISKK1250 pKa = 10.75SGWKK1254 pKa = 8.93KK1255 pKa = 8.5WKK1257 pKa = 10.01QLVEE1261 pKa = 4.26EE1262 pKa = 4.25VGEE1265 pKa = 4.07LSSEE1269 pKa = 4.02EE1270 pKa = 3.88EE1271 pKa = 4.07QYY1273 pKa = 11.56LEE1275 pKa = 4.34NNPMLYY1281 pKa = 10.1YY1282 pKa = 10.27EE1283 pKa = 4.46KK1284 pKa = 10.69SRR1286 pKa = 11.84NDD1288 pKa = 3.25VYY1290 pKa = 11.68SSVIKK1295 pKa = 10.57IKK1297 pKa = 10.2QKK1299 pKa = 10.97CQDD1302 pKa = 3.33FDD1304 pKa = 4.07VKK1306 pKa = 10.87QSLSSRR1312 pKa = 11.84YY1313 pKa = 10.16GITEE1317 pKa = 3.53NMASFFCTFIKK1328 pKa = 10.09VCKK1331 pKa = 9.63IGKK1334 pKa = 9.37EE1335 pKa = 3.85KK1336 pKa = 10.89DD1337 pKa = 3.66SLVGWMLKK1345 pKa = 8.96CTEE1348 pKa = 4.55NGISDD1353 pKa = 4.71LSQMFPKK1360 pKa = 10.44FKK1362 pKa = 10.25LYY1364 pKa = 11.08NEE1366 pKa = 4.81IIHH1369 pKa = 6.23YY1370 pKa = 10.09ISVISNQSYY1379 pKa = 10.23LVDD1382 pKa = 2.85VDD1384 pKa = 3.77YY1385 pKa = 10.93IQRR1388 pKa = 11.84GRR1390 pKa = 11.84SQITVLHH1397 pKa = 6.35NKK1399 pKa = 8.48TSEE1402 pKa = 4.12LEE1404 pKa = 4.03LFYY1407 pKa = 10.77EE1408 pKa = 4.53TVKK1411 pKa = 11.03NVWFDD1416 pKa = 3.63VEE1418 pKa = 4.33CDD1420 pKa = 3.89EE1421 pKa = 4.44ITKK1424 pKa = 10.29DD1425 pKa = 2.81AYY1427 pKa = 10.32RR1428 pKa = 11.84RR1429 pKa = 11.84LFRR1432 pKa = 11.84EE1433 pKa = 3.9YY1434 pKa = 10.06MEE1436 pKa = 4.4EE1437 pKa = 3.96FDD1439 pKa = 3.49WLKK1442 pKa = 8.87WTEE1445 pKa = 4.11KK1446 pKa = 7.95EE1447 pKa = 4.08TKK1449 pKa = 10.53AFLNCSSRR1457 pKa = 11.84QLANYY1462 pKa = 8.41VRR1464 pKa = 11.84NVVGKK1469 pKa = 9.99NRR1471 pKa = 11.84TLTFFDD1477 pKa = 4.04TVAKK1481 pKa = 10.09GSNYY1485 pKa = 9.73PYY1487 pKa = 10.73LLTRR1491 pKa = 11.84IFQKK1495 pKa = 10.57DD1496 pKa = 3.13KK1497 pKa = 10.61KK1498 pKa = 9.27IQVVTGKK1505 pKa = 10.25DD1506 pKa = 3.23VSINKK1511 pKa = 9.45NDD1513 pKa = 3.92IIFSNMKK1520 pKa = 9.79ILLNLPYY1527 pKa = 10.17KK1528 pKa = 10.39EE1529 pKa = 4.14SYY1531 pKa = 10.47KK1532 pKa = 10.6MNTLKK1537 pKa = 10.71EE1538 pKa = 4.7LIPKK1542 pKa = 9.94LDD1544 pKa = 3.72LSEE1547 pKa = 4.27LTSKK1551 pKa = 9.76EE1552 pKa = 3.68AKK1554 pKa = 9.62KK1555 pKa = 11.06YY1556 pKa = 10.6KK1557 pKa = 9.84ILKK1560 pKa = 9.93LVLSDD1565 pKa = 3.99KK1566 pKa = 11.37KK1567 pKa = 10.97EE1568 pKa = 4.0DD1569 pKa = 3.68VKK1571 pKa = 11.64NEE1573 pKa = 3.61LFKK1576 pKa = 11.57YY1577 pKa = 10.39SFEE1580 pKa = 4.22NHH1582 pKa = 5.35LTWYY1586 pKa = 10.31SQAQHH1591 pKa = 6.07FNKK1594 pKa = 9.95EE1595 pKa = 3.93NKK1597 pKa = 7.85SWEE1600 pKa = 4.66GIGCLTTIISTLTIKK1615 pKa = 9.97TIMMDD1620 pKa = 3.46SLIQEE1625 pKa = 4.56IIVNDD1630 pKa = 4.07LSSFKK1635 pKa = 10.85LHH1637 pKa = 6.92LDD1639 pKa = 3.23VYY1641 pKa = 9.08MKK1643 pKa = 10.26IIKK1646 pKa = 7.7EE1647 pKa = 4.16HH1648 pKa = 6.32KK1649 pKa = 10.39LEE1651 pKa = 5.16LGDD1654 pKa = 5.64NVDD1657 pKa = 5.85DD1658 pKa = 4.86DD1659 pKa = 5.35LKK1661 pKa = 10.8LSKK1664 pKa = 11.04YY1665 pKa = 10.44GISKK1669 pKa = 10.04SFKK1672 pKa = 8.86GSKK1675 pKa = 9.67IKK1677 pKa = 10.38ISPEE1681 pKa = 3.73LKK1683 pKa = 10.47SNVAFLEE1690 pKa = 4.01NSTLALTNGNMKK1702 pKa = 10.34LVVPMIDD1709 pKa = 2.85IDD1711 pKa = 4.52SNFVEE1716 pKa = 5.34KK1717 pKa = 10.63RR1718 pKa = 11.84NCVQTLYY1725 pKa = 10.85LIEE1728 pKa = 4.46SKK1730 pKa = 10.66RR1731 pKa = 11.84LARR1734 pKa = 11.84TFQEE1738 pKa = 5.14RR1739 pKa = 11.84RR1740 pKa = 11.84DD1741 pKa = 3.78ADD1743 pKa = 3.6HH1744 pKa = 6.85NGYY1747 pKa = 9.92IIEE1750 pKa = 4.88NIWIDD1755 pKa = 3.27SRR1757 pKa = 11.84SYY1759 pKa = 10.24NKK1761 pKa = 9.19VRR1763 pKa = 11.84HH1764 pKa = 5.44GEE1766 pKa = 4.08IIKK1769 pKa = 10.61SRR1771 pKa = 11.84MIMGGKK1777 pKa = 9.17DD1778 pKa = 3.38VKK1780 pKa = 10.87LSTIMNFEE1788 pKa = 3.88VWKK1791 pKa = 10.71KK1792 pKa = 8.78ITLPTNEE1799 pKa = 5.11KK1800 pKa = 10.52LFDD1803 pKa = 3.41WGEE1806 pKa = 3.92LGEE1809 pKa = 4.95KK1810 pKa = 9.46IVKK1813 pKa = 9.78QEE1815 pKa = 3.96SLDD1818 pKa = 3.64FQSYY1822 pKa = 9.78VLTKK1826 pKa = 10.68LEE1828 pKa = 4.32SFPKK1832 pKa = 10.31RR1833 pKa = 11.84MPTNEE1838 pKa = 4.24MFHH1841 pKa = 7.63QSMEE1845 pKa = 4.03QNYY1848 pKa = 9.08FDD1850 pKa = 4.22CKK1852 pKa = 10.5EE1853 pKa = 3.85YY1854 pKa = 11.2LNFISRR1860 pKa = 11.84VEE1862 pKa = 4.04FFQQVEE1868 pKa = 4.19DD1869 pKa = 3.98PDD1871 pKa = 3.91YY1872 pKa = 11.85DD1873 pKa = 3.9EE1874 pKa = 5.84LVKK1877 pKa = 10.32KK1878 pKa = 10.65DD1879 pKa = 3.56KK1880 pKa = 11.26EE1881 pKa = 4.23EE1882 pKa = 4.34EE1883 pKa = 3.9FDD1885 pKa = 3.27KK1886 pKa = 11.34TLIDD1890 pKa = 3.78RR1891 pKa = 11.84FNEE1894 pKa = 4.32LVFNTQALKK1903 pKa = 10.56RR1904 pKa = 11.84AIQKK1908 pKa = 7.91TVEE1911 pKa = 4.08FDD1913 pKa = 3.26SCLINLDD1920 pKa = 3.61NVLMKK1925 pKa = 10.79AQTDD1929 pKa = 3.99FSYY1932 pKa = 10.86CRR1934 pKa = 11.84HH1935 pKa = 5.72LVYY1938 pKa = 10.39GIKK1941 pKa = 9.61DD1942 pKa = 3.64TEE1944 pKa = 4.39TTFPNTLFYY1953 pKa = 10.96KK1954 pKa = 10.45FNHH1957 pKa = 5.38EE1958 pKa = 3.94LRR1960 pKa = 11.84RR1961 pKa = 11.84RR1962 pKa = 11.84IPDD1965 pKa = 3.25NDD1967 pKa = 3.34EE1968 pKa = 4.04LLEE1971 pKa = 4.15VMSKK1975 pKa = 10.96GDD1977 pKa = 3.64SGNLLTIYY1985 pKa = 9.83QQIALNLLFATPTDD1999 pKa = 4.12FTSLTTVKK2007 pKa = 10.25SLRR2010 pKa = 11.84EE2011 pKa = 4.12FILLGYY2017 pKa = 9.12KK2018 pKa = 10.12PKK2020 pKa = 10.32EE2021 pKa = 4.19SRR2023 pKa = 11.84SSRR2026 pKa = 11.84SSTRR2030 pKa = 11.84LGIYY2034 pKa = 10.01LPNNDD2039 pKa = 5.26LEE2041 pKa = 4.46QKK2043 pKa = 9.37MLSKK2047 pKa = 10.39FQIHH2051 pKa = 6.76PKK2053 pKa = 10.08SEE2055 pKa = 3.93QLFDD2059 pKa = 4.93LLNAEE2064 pKa = 4.21QKK2066 pKa = 10.87LLEE2069 pKa = 4.09EE2070 pKa = 5.54AIDD2073 pKa = 3.92EE2074 pKa = 4.17VSQMIEE2080 pKa = 3.54KK2081 pKa = 6.27TTNRR2085 pKa = 11.84RR2086 pKa = 11.84VKK2088 pKa = 10.14MPLLTQVVGYY2098 pKa = 10.66EE2099 pKa = 4.13EE2100 pKa = 4.52DD2101 pKa = 3.96LKK2103 pKa = 11.34LLKK2106 pKa = 10.49DD2107 pKa = 4.48FRR2109 pKa = 11.84AHH2111 pKa = 7.37ALNLEE2116 pKa = 4.14NEE2118 pKa = 4.53KK2119 pKa = 10.74EE2120 pKa = 4.24SEE2122 pKa = 4.24STKK2125 pKa = 11.15DD2126 pKa = 3.96SLEE2129 pKa = 4.22CLDD2132 pKa = 4.36NLEE2135 pKa = 4.86EE2136 pKa = 4.29NDD2138 pKa = 3.28ISLSAEE2144 pKa = 4.11EE2145 pKa = 4.65EE2146 pKa = 4.28DD2147 pKa = 5.79DD2148 pKa = 5.45DD2149 pKa = 4.56LTHH2152 pKa = 7.1SLTDD2156 pKa = 3.36SDD2158 pKa = 3.91EE2159 pKa = 4.44SADD2162 pKa = 3.42IGEE2165 pKa = 4.83DD2166 pKa = 3.71FNLLNHH2172 pKa = 6.71LQNSYY2177 pKa = 10.87KK2178 pKa = 9.95EE2179 pKa = 4.19KK2180 pKa = 10.74KK2181 pKa = 8.85VLKK2184 pKa = 9.88RR2185 pKa = 11.84NCFLYY2190 pKa = 11.07LNVDD2194 pKa = 2.73ITYY2197 pKa = 10.52ILRR2200 pKa = 11.84NPKK2203 pKa = 9.64FDD2205 pKa = 4.41IKK2207 pKa = 11.26SQVQKK2212 pKa = 10.33MNCTFHH2218 pKa = 7.87LSDD2221 pKa = 3.33MTILVNGAKK2230 pKa = 10.21DD2231 pKa = 4.03FEE2233 pKa = 5.11VYY2235 pKa = 8.99WPNDD2239 pKa = 3.22DD2240 pKa = 3.76SAEE2243 pKa = 3.88FSIFYY2248 pKa = 10.46HH2249 pKa = 5.39STLPEE2254 pKa = 3.98LPYY2257 pKa = 10.68SQNILSKK2264 pKa = 9.43EE2265 pKa = 3.84IKK2267 pKa = 9.98KK2268 pKa = 10.31ISPLPGGSCLFNCFVYY2284 pKa = 10.87LLSNHH2289 pKa = 5.67GKK2291 pKa = 9.47YY2292 pKa = 10.18FKK2294 pKa = 10.48QEE2296 pKa = 3.62EE2297 pKa = 4.22LRR2299 pKa = 11.84QIVHH2303 pKa = 7.25DD2304 pKa = 4.25SDD2306 pKa = 3.75HH2307 pKa = 6.96LKK2309 pKa = 10.99LLDD2312 pKa = 4.11EE2313 pKa = 5.35DD2314 pKa = 3.97PHH2316 pKa = 8.16KK2317 pKa = 10.85KK2318 pKa = 10.48AILSNDD2324 pKa = 2.67EE2325 pKa = 3.86WGQEE2329 pKa = 3.71EE2330 pKa = 4.81DD2331 pKa = 4.25IEE2333 pKa = 4.92TICHH2337 pKa = 5.82EE2338 pKa = 4.59LDD2340 pKa = 3.43VSVLVVTDD2348 pKa = 3.73YY2349 pKa = 11.68AILQYY2354 pKa = 11.31NEE2356 pKa = 3.98TGQKK2360 pKa = 9.64IGILINYY2367 pKa = 7.06EE2368 pKa = 3.96NVHH2371 pKa = 6.13FDD2373 pKa = 3.33VLEE2376 pKa = 4.05

Molecular weight:
276.06 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A2S1B6H7|A0A2S1B6H7_9VIRU Replicase OS=Apple rubbery wood virus 2 OX=2164103 GN=RdRp PE=4 SV=1
MM1 pKa = 7.86AEE3 pKa = 4.3GNFTLTGLTTALTLINHH20 pKa = 7.61LLTVSATNFKK30 pKa = 10.5AAAKK34 pKa = 10.36ANARR38 pKa = 11.84YY39 pKa = 8.24FAYY42 pKa = 10.43DD43 pKa = 3.53GFNANEE49 pKa = 4.13ILNAFITIFLTNTNSDD65 pKa = 3.72DD66 pKa = 4.3ALQDD70 pKa = 3.09LCDD73 pKa = 3.63IVNVGLTRR81 pKa = 11.84GNIRR85 pKa = 11.84EE86 pKa = 4.16DD87 pKa = 3.53QLKK90 pKa = 8.57KK91 pKa = 8.08TSKK94 pKa = 9.97RR95 pKa = 11.84GKK97 pKa = 9.71EE98 pKa = 3.95RR99 pKa = 11.84IEE101 pKa = 4.06EE102 pKa = 4.01LSKK105 pKa = 10.9KK106 pKa = 10.65YY107 pKa = 10.4NIKK110 pKa = 10.03IKK112 pKa = 9.11KK113 pKa = 7.08TKK115 pKa = 10.39NEE117 pKa = 4.05SFTLSNSTLTFTRR130 pKa = 11.84SISVFPYY137 pKa = 10.21VASQLLATGSCILEE151 pKa = 3.94QNNCKK156 pKa = 10.31FGTDD160 pKa = 3.45SLPAAFKK167 pKa = 10.7HH168 pKa = 6.38SGFASLIPNIADD180 pKa = 3.36NNYY183 pKa = 10.05CLVLFQCHH191 pKa = 4.36VAYY194 pKa = 9.6MISFGKK200 pKa = 10.19KK201 pKa = 8.89INPGNKK207 pKa = 9.48DD208 pKa = 4.88DD209 pKa = 5.52DD210 pKa = 4.16STWYY214 pKa = 10.15KK215 pKa = 10.48KK216 pKa = 10.02QSQYY220 pKa = 11.62SVAAWNNLSLYY231 pKa = 10.26NNDD234 pKa = 3.21YY235 pKa = 11.0RR236 pKa = 11.84KK237 pKa = 7.79TAFKK241 pKa = 11.01NLGLDD246 pKa = 3.27SHH248 pKa = 6.52GKK250 pKa = 10.09YY251 pKa = 10.58GEE253 pKa = 4.61LYY255 pKa = 10.66LKK257 pKa = 10.25IVNNLRR263 pKa = 11.84KK264 pKa = 9.65SIKK267 pKa = 10.35GEE269 pKa = 3.95EE270 pKa = 4.14VKK272 pKa = 10.6PADD275 pKa = 3.88LKK277 pKa = 11.3PFIKK281 pKa = 10.03EE282 pKa = 4.09DD283 pKa = 4.78KK284 pKa = 9.91DD285 pKa = 4.1LKK287 pKa = 9.51WW288 pKa = 4.29

Molecular weight:
32.35 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

2

5

3720

286

2376

744.0

85.87

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

3.844 ± 1.228

1.72 ± 0.127

6.048 ± 0.212

7.554 ± 0.714

5.376 ± 0.274

4.032 ± 0.594

2.097 ± 0.22

7.043 ± 0.522

9.435 ± 0.347

10.161 ± 0.419

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.634 ± 0.389

6.667 ± 0.601

2.527 ± 0.211

3.253 ± 0.55

3.548 ± 0.509

8.091 ± 0.296

5.753 ± 0.389

5.349 ± 0.306

0.806 ± 0.087

4.059 ± 0.039

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski