Human papillomavirus 148

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 12

Average proteome isoelectric point is 6.08

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E7BQC8|E7BQC8_9PAPI Major capsid protein L1 OS=Human papillomavirus 148 OX=942038 GN=L1 PE=3 SV=1
MM1 pKa = 6.6EE2 pKa = 4.44TKK4 pKa = 10.15SRR6 pKa = 11.84RR7 pKa = 11.84KK8 pKa = 9.41RR9 pKa = 11.84AAPDD13 pKa = 2.91QLYY16 pKa = 9.56RR17 pKa = 11.84HH18 pKa = 6.65CLQGGDD24 pKa = 5.15CIPDD28 pKa = 3.33VQNKK32 pKa = 9.51YY33 pKa = 8.24EE34 pKa = 4.07QNTWADD40 pKa = 3.35VLLKK44 pKa = 11.01VFGSLLYY51 pKa = 10.5FGNLGIGTGRR61 pKa = 11.84GSGGSLGYY69 pKa = 10.25KK70 pKa = 9.97PLGTTRR76 pKa = 11.84IGQAAPITPARR87 pKa = 11.84PSILIDD93 pKa = 3.38AVGPPDD99 pKa = 5.5IIPVDD104 pKa = 3.69AGAPAVVPLSEE115 pKa = 4.18GTIDD119 pKa = 3.6TGLVAPDD126 pKa = 4.14AGPGVGVDD134 pKa = 3.56EE135 pKa = 5.24LEE137 pKa = 5.14LYY139 pKa = 9.29TISDD143 pKa = 3.83PTSDD147 pKa = 3.32VGGVQPTPTVVSTEE161 pKa = 3.93EE162 pKa = 3.95GAVAVIDD169 pKa = 3.94AQPVPEE175 pKa = 4.99RR176 pKa = 11.84PVQVYY181 pKa = 9.15FDD183 pKa = 4.88PNPTATSTLHH193 pKa = 6.59IFPAPSITSTDD204 pKa = 2.94VNIFVDD210 pKa = 3.92SFSSQVIGGFDD221 pKa = 4.32EE222 pKa = 5.54IPLQRR227 pKa = 11.84LDD229 pKa = 3.52YY230 pKa = 11.31SEE232 pKa = 5.71FDD234 pKa = 3.57IEE236 pKa = 5.54DD237 pKa = 3.77IPSTSTPSQKK247 pKa = 10.39LEE249 pKa = 4.17KK250 pKa = 10.16VVSRR254 pKa = 11.84AKK256 pKa = 10.23SYY258 pKa = 8.7YY259 pKa = 9.87NKK261 pKa = 10.26YY262 pKa = 9.17IKK264 pKa = 9.81QVPVTSQQFLKK275 pKa = 10.66QPSSLVQFEE284 pKa = 4.67FEE286 pKa = 4.73NPAFDD291 pKa = 4.58PDD293 pKa = 3.55VTIEE297 pKa = 3.87FEE299 pKa = 3.92RR300 pKa = 11.84DD301 pKa = 3.09LAEE304 pKa = 4.27VQASPDD310 pKa = 3.39ADD312 pKa = 3.43FADD315 pKa = 3.49ITKK318 pKa = 10.27LHH320 pKa = 6.6RR321 pKa = 11.84PQLNVVEE328 pKa = 4.56GVVRR332 pKa = 11.84VSRR335 pKa = 11.84LGEE338 pKa = 3.85TGTISTRR345 pKa = 11.84SGTVIGQRR353 pKa = 11.84VHH355 pKa = 7.1FYY357 pKa = 11.09HH358 pKa = 7.66DD359 pKa = 3.07ISSIAVAEE367 pKa = 4.7DD368 pKa = 3.3IEE370 pKa = 4.38MQVFGEE376 pKa = 4.33FPGLNTVVDD385 pKa = 5.36DD386 pKa = 4.22ILATTVVDD394 pKa = 4.95LNNATDD400 pKa = 3.86LGEE403 pKa = 4.74DD404 pKa = 4.01ALLDD408 pKa = 3.71TYY410 pKa = 11.76GEE412 pKa = 4.76DD413 pKa = 3.45FTNTHH418 pKa = 6.09LVINITDD425 pKa = 3.68EE426 pKa = 4.38TTDD429 pKa = 3.42TLSFPTISTEE439 pKa = 3.73YY440 pKa = 9.87SVNVLTPQLTNDD452 pKa = 4.48IIVSYY457 pKa = 10.34PNDD460 pKa = 3.3NAVINSFTPSLTPVAPSYY478 pKa = 11.06IPDD481 pKa = 3.8YY482 pKa = 11.1YY483 pKa = 11.43ADD485 pKa = 4.4FYY487 pKa = 11.06LYY489 pKa = 10.23PSFLPKK495 pKa = 9.42KK496 pKa = 9.54RR497 pKa = 11.84RR498 pKa = 11.84RR499 pKa = 11.84IDD501 pKa = 3.16IVV503 pKa = 3.14

Molecular weight: 54.63 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E7BQC6|E7BQC6_9PAPI E4 (Fragment) OS=Human papillomavirus 148 OX=942038 GN=E4 PE=4 SV=1
MM1 pKa = 7.35EE2 pKa = 4.45TQQTLTEE9 pKa = 4.29RR10 pKa = 11.84FAAQQEE16 pKa = 4.35MQMTLIEE23 pKa = 4.19QEE25 pKa = 4.25STDD28 pKa = 3.65LRR30 pKa = 11.84DD31 pKa = 3.99HH32 pKa = 6.51IKK34 pKa = 10.25YY35 pKa = 8.58WDD37 pKa = 3.7SVRR40 pKa = 11.84LEE42 pKa = 4.13NLLAYY47 pKa = 9.51YY48 pKa = 9.93SRR50 pKa = 11.84KK51 pKa = 9.73EE52 pKa = 4.3GYY54 pKa = 7.26THH56 pKa = 7.72LGLQPLPALTVSEE69 pKa = 4.73YY70 pKa = 10.48KK71 pKa = 10.6CKK73 pKa = 10.35EE74 pKa = 4.06AIKK77 pKa = 10.12MKK79 pKa = 10.73LLLEE83 pKa = 4.14SLKK86 pKa = 10.7DD87 pKa = 3.28SRR89 pKa = 11.84YY90 pKa = 10.5GYY92 pKa = 10.14EE93 pKa = 3.75PWTLSEE99 pKa = 4.25VSAEE103 pKa = 4.2IINTNPRR110 pKa = 11.84NAFKK114 pKa = 10.73KK115 pKa = 10.09KK116 pKa = 10.15AFTVTVFFDD125 pKa = 3.59NDD127 pKa = 3.19QSNSFPYY134 pKa = 10.11ICWDD138 pKa = 3.66HH139 pKa = 7.87IYY141 pKa = 10.78YY142 pKa = 9.95QDD144 pKa = 5.46EE145 pKa = 3.94KK146 pKa = 11.62SEE148 pKa = 4.02WQKK151 pKa = 10.97VAGQVDD157 pKa = 3.78INGLYY162 pKa = 10.01FRR164 pKa = 11.84EE165 pKa = 4.21VTGDD169 pKa = 2.81ITYY172 pKa = 7.32FTLFQPDD179 pKa = 3.53AEE181 pKa = 4.69RR182 pKa = 11.84YY183 pKa = 8.05GQTGQWSVTYY193 pKa = 10.31KK194 pKa = 10.67NHH196 pKa = 5.92TLSTSVTSSSRR207 pKa = 11.84TASDD211 pKa = 3.77LEE213 pKa = 4.24NRR215 pKa = 11.84PPTHH219 pKa = 7.24PISSPKK225 pKa = 9.33TPRR228 pKa = 11.84KK229 pKa = 9.49RR230 pKa = 11.84RR231 pKa = 11.84RR232 pKa = 11.84QTGEE236 pKa = 3.51DD237 pKa = 3.39TTRR240 pKa = 11.84EE241 pKa = 4.37SPTSTSSGLRR251 pKa = 11.84FRR253 pKa = 11.84RR254 pKa = 11.84RR255 pKa = 11.84RR256 pKa = 11.84TEE258 pKa = 3.6QGEE261 pKa = 4.32PTTDD265 pKa = 3.41GYY267 pKa = 9.16NTRR270 pKa = 11.84STPRR274 pKa = 11.84RR275 pKa = 11.84RR276 pKa = 11.84RR277 pKa = 11.84AAVGSAVSPEE287 pKa = 4.06EE288 pKa = 4.03VGSGTRR294 pKa = 11.84SVPRR298 pKa = 11.84TGLTRR303 pKa = 11.84NQRR306 pKa = 11.84LQAEE310 pKa = 4.41ARR312 pKa = 11.84DD313 pKa = 3.77PTLILLQGCANSLKK327 pKa = 10.13CFRR330 pKa = 11.84YY331 pKa = 9.35RR332 pKa = 11.84CSHH335 pKa = 5.62KK336 pKa = 10.23HH337 pKa = 3.7SHH339 pKa = 6.86LYY341 pKa = 10.02LAASTVFAWMYY352 pKa = 10.7NSNEE356 pKa = 3.69KK357 pKa = 10.18SAEE360 pKa = 3.52GRR362 pKa = 11.84MLIAFSSNTQRR373 pKa = 11.84DD374 pKa = 3.79VFLKK378 pKa = 10.73SVTIPKK384 pKa = 9.36GCHH387 pKa = 4.15YY388 pKa = 10.89CFGNLDD394 pKa = 3.93CLL396 pKa = 3.95

Molecular weight: 45.48 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2368

93

602

338.3

38.26

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.87 ± 0.376

2.492 ± 0.712

6.757 ± 0.561

5.954 ± 0.441

4.899 ± 0.567

5.068 ± 0.716

1.816 ± 0.277

5.152 ± 0.518

5.11 ± 0.644

8.868 ± 0.917

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.563 ± 0.424

4.941 ± 0.577

6.123 ± 1.094

4.35 ± 0.222

5.659 ± 0.718

7.095 ± 0.786

7.179 ± 0.699

6.292 ± 0.869

1.182 ± 0.247

3.632 ± 0.374
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski