Average proteome isoelectric point is 6.37

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

    

All

Note: above files contain also dissociation constants (pKa)

Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

    

>tr|A0A1L3KKP0|A0A1L3KKP0_9VIRU RdRP_1 domain-containing protein OS=Hubei picorna-like virus 60 OX=1923143 PE=4 SV=1
MM1 pKa = 7.52QNNNNNKK8 pKa = 9.23PCDD11 pKa = 3.75ALKK14 pKa = 10.74CALRR18 pKa = 11.84EE19 pKa = 3.76QADD22 pKa = 4.03PVRR25 pKa = 11.84HH26 pKa = 5.96LVDD29 pKa = 3.1AHH31 pKa = 6.34KK32 pKa = 10.33IKK34 pKa = 10.36PFSYY38 pKa = 10.65EE39 pKa = 3.62EE40 pKa = 4.02VSMVKK45 pKa = 10.5ANNITSPCFFEE56 pKa = 4.8LLATIRR62 pKa = 11.84PLTFPSPQAAQQFVYY77 pKa = 10.87NVVADD82 pKa = 3.99SYY84 pKa = 9.81TDD86 pKa = 3.33KK87 pKa = 11.14RR88 pKa = 11.84SGGQPSARR96 pKa = 11.84DD97 pKa = 3.41NFTKK101 pKa = 10.53RR102 pKa = 11.84FFAKK106 pKa = 10.44DD107 pKa = 3.35GTGGMQFDD115 pKa = 4.84DD116 pKa = 4.58LDD118 pKa = 3.97VVARR122 pKa = 11.84ALNCTFAVCATKK134 pKa = 10.15IPKK137 pKa = 9.59QNSRR141 pKa = 11.84GTNTKK146 pKa = 9.8YY147 pKa = 9.25FTIGHH152 pKa = 5.36SPEE155 pKa = 3.5RR156 pKa = 11.84VYY158 pKa = 10.92IKK160 pKa = 9.53WVYY163 pKa = 7.82NHH165 pKa = 7.41HH166 pKa = 6.0YY167 pKa = 10.52QLIKK171 pKa = 10.55PIDD174 pKa = 3.99DD175 pKa = 3.89TTSSSTMSDD184 pKa = 3.49DD185 pKa = 3.88EE186 pKa = 4.26EE187 pKa = 6.12APLIRR192 pKa = 11.84YY193 pKa = 6.78QTHH196 pKa = 7.05PNNTLNGKK204 pKa = 8.69PEE206 pKa = 3.82QPQDD210 pKa = 3.51EE211 pKa = 4.68FKK213 pKa = 10.06KK214 pKa = 9.17TVMNTPCAFTKK225 pKa = 10.54KK226 pKa = 8.91KK227 pKa = 8.56TLQSLTPPSSTTPTISEE244 pKa = 4.18DD245 pKa = 3.38EE246 pKa = 4.28EE247 pKa = 4.9EE248 pKa = 4.45IVSAVNLIRR257 pKa = 11.84EE258 pKa = 4.37HH259 pKa = 6.21LLKK262 pKa = 10.99DD263 pKa = 3.91FFPGLDD269 pKa = 3.26THH271 pKa = 6.82VKK273 pKa = 9.43VAVATSIAASIVSVSANISALIGGKK298 pKa = 9.87LGPINKK304 pKa = 9.06AVQIASIVTSLTSFTSNVSLALRR327 pKa = 11.84ANEE330 pKa = 4.05IKK332 pKa = 10.9FNFDD336 pKa = 2.67KK337 pKa = 11.29VMNSIPGLASTLHH350 pKa = 5.79STFKK354 pKa = 10.91ANSAAWIYY362 pKa = 7.52PTISALVSLIIGGLTIFNVSDD383 pKa = 3.09IKK385 pKa = 11.08EE386 pKa = 4.21VIQAGSLLKK395 pKa = 9.95TINAFGTEE403 pKa = 4.02AKK405 pKa = 10.65NITKK409 pKa = 10.33YY410 pKa = 10.9VLEE413 pKa = 5.19DD414 pKa = 3.75LLEE417 pKa = 5.59LDD419 pKa = 3.54VTGDD423 pKa = 4.38HH424 pKa = 6.55IQHH427 pKa = 6.92KK428 pKa = 10.45ALIDD432 pKa = 3.49MAKK435 pKa = 10.03RR436 pKa = 11.84SAEE439 pKa = 4.06LCVMPHH445 pKa = 5.75YY446 pKa = 10.89KK447 pKa = 10.52FFGDD451 pKa = 3.58PGLLQEE457 pKa = 5.08LKK459 pKa = 10.72SISEE463 pKa = 4.25KK464 pKa = 10.57ATDD467 pKa = 3.53LTAKK471 pKa = 10.32KK472 pKa = 9.44FANPKK477 pKa = 7.47TSQVARR483 pKa = 11.84MASQTLMHH491 pKa = 6.62NVAQLQEE498 pKa = 4.22KK499 pKa = 9.07EE500 pKa = 3.88LAIRR504 pKa = 11.84TVFDD508 pKa = 3.73ASARR512 pKa = 11.84QEE514 pKa = 4.26TFGVLLAGAPSIGKK528 pKa = 9.85SYY530 pKa = 11.28LLTQIWAKK538 pKa = 10.25LSPIFGYY545 pKa = 10.59KK546 pKa = 9.19PDD548 pKa = 4.71LYY550 pKa = 10.89NLTISRR556 pKa = 11.84SDD558 pKa = 3.48GFFEE562 pKa = 4.77PYY564 pKa = 10.83GMQDD568 pKa = 2.88CGFVNEE574 pKa = 4.49FMGSRR579 pKa = 11.84EE580 pKa = 4.06DD581 pKa = 4.77AFLTHH586 pKa = 6.87LNSTISADD594 pKa = 3.64PKK596 pKa = 9.63NLEE599 pKa = 3.81GAFQKK604 pKa = 10.37SQPAQFKK611 pKa = 10.87LVFLTSNDD619 pKa = 3.01IAPEE623 pKa = 4.1LTRR626 pKa = 11.84HH627 pKa = 5.4LTDD630 pKa = 3.26SAAKK634 pKa = 10.04AVWNRR639 pKa = 11.84ILRR642 pKa = 11.84IQVEE646 pKa = 4.31DD647 pKa = 4.19PKK649 pKa = 11.17CQGRR653 pKa = 11.84QGINTHH659 pKa = 5.43RR660 pKa = 11.84RR661 pKa = 11.84ADD663 pKa = 4.1FSHH666 pKa = 6.21LTIKK670 pKa = 10.62KK671 pKa = 10.31VMDD674 pKa = 3.52TEE676 pKa = 4.33ALSKK680 pKa = 10.69EE681 pKa = 3.85RR682 pKa = 11.84TLNSLQTITLDD693 pKa = 3.51SLIVEE698 pKa = 4.8IAHH701 pKa = 4.76QVARR705 pKa = 11.84RR706 pKa = 11.84EE707 pKa = 3.91KK708 pKa = 10.25RR709 pKa = 11.84YY710 pKa = 9.5LQSIVNNDD718 pKa = 2.7IFNNEE723 pKa = 3.6QEE725 pKa = 4.82DD726 pKa = 3.42IRR728 pKa = 11.84KK729 pKa = 9.86RR730 pKa = 11.84IARR733 pKa = 11.84LDD735 pKa = 3.91EE736 pKa = 4.67IMATTNWANAEE747 pKa = 4.0GGNTYY752 pKa = 10.76NIIRR756 pKa = 11.84LQGPLEE762 pKa = 4.15TGKK765 pKa = 8.63TEE767 pKa = 4.19LAKK770 pKa = 10.81EE771 pKa = 3.71MAAAITSVYY780 pKa = 10.07YY781 pKa = 10.48KK782 pKa = 10.32RR783 pKa = 11.84EE784 pKa = 4.01LVIITQPSQFLEE796 pKa = 4.53KK797 pKa = 9.93PSKK800 pKa = 10.79HH801 pKa = 5.53PMVYY805 pKa = 10.74LLDD808 pKa = 4.4DD809 pKa = 3.95VVDD812 pKa = 3.99EE813 pKa = 4.69TTHH816 pKa = 6.3NDD818 pKa = 2.92YY819 pKa = 11.03FKK821 pKa = 10.55WINSCNSEE829 pKa = 4.2SLFIITSNKK838 pKa = 10.04SYY840 pKa = 10.35TRR842 pKa = 11.84TLTTQAWLKK851 pKa = 9.61TKK853 pKa = 10.28ALNVFGFAGEE863 pKa = 4.37EE864 pKa = 3.69EE865 pKa = 4.45HH866 pKa = 7.43FYY868 pKa = 10.73IDD870 pKa = 3.37TQHH873 pKa = 5.09THH875 pKa = 5.76SGIARR880 pKa = 11.84RR881 pKa = 11.84LGLYY885 pKa = 10.33GRR887 pKa = 11.84VDD889 pKa = 4.95AITEE893 pKa = 4.05KK894 pKa = 11.01GIEE897 pKa = 4.28TVVNDD902 pKa = 4.49PSMHH906 pKa = 5.09MTIDD910 pKa = 3.45ATPGFQYY917 pKa = 10.26TINGTPIMPEE927 pKa = 3.88DD928 pKa = 3.81LKK930 pKa = 10.96QHH932 pKa = 5.35VFRR935 pKa = 11.84TYY937 pKa = 8.97TAFIAKK943 pKa = 7.99SHH945 pKa = 6.99KK946 pKa = 10.11IQVLNSTYY954 pKa = 11.06SNPTQEE960 pKa = 4.38YY961 pKa = 9.5DD962 pKa = 3.79VKK964 pKa = 10.31ITADD968 pKa = 5.05DD969 pKa = 3.53IDD971 pKa = 3.78SLYY974 pKa = 11.29NAFSNITNITSLLFFGAKK992 pKa = 8.81GASVTISKK1000 pKa = 10.34RR1001 pKa = 11.84VMVAIPRR1008 pKa = 11.84DD1009 pKa = 3.69MHH1011 pKa = 6.95DD1012 pKa = 3.53ATALIPNKK1020 pKa = 10.07KK1021 pKa = 10.21LEE1023 pKa = 4.09TRR1025 pKa = 11.84EE1026 pKa = 3.98EE1027 pKa = 4.32VISLAKK1033 pKa = 10.43RR1034 pKa = 11.84LGAFMAKK1041 pKa = 10.29LIPDD1045 pKa = 3.71IKK1047 pKa = 10.43IYY1049 pKa = 10.32FHH1051 pKa = 7.24LAGQPPIVLIDD1062 pKa = 3.38KK1063 pKa = 10.36QLFIGAHH1070 pKa = 4.88EE1071 pKa = 4.27TLSIDD1076 pKa = 3.34IVRR1079 pKa = 11.84SSDD1082 pKa = 2.91AFHH1085 pKa = 6.75WVFQGRR1091 pKa = 11.84AHH1093 pKa = 7.86RR1094 pKa = 11.84LRR1096 pKa = 11.84DD1097 pKa = 3.13EE1098 pKa = 4.76DD1099 pKa = 3.97FALFTSTGVLPPAMQEE1115 pKa = 3.85LPQFIIAAIVAKK1127 pKa = 9.1YY1128 pKa = 10.54ASMRR1132 pKa = 11.84KK1133 pKa = 9.42EE1134 pKa = 3.8EE1135 pKa = 4.21TPLIRR1140 pKa = 11.84TWIEE1144 pKa = 3.52HH1145 pKa = 4.87YY1146 pKa = 10.32KK1147 pKa = 8.76IEE1149 pKa = 5.23RR1150 pKa = 11.84MIRR1153 pKa = 11.84DD1154 pKa = 3.53YY1155 pKa = 11.27KK1156 pKa = 10.98EE1157 pKa = 4.23RR1158 pKa = 11.84GLLSFLFEE1166 pKa = 4.61HH1167 pKa = 7.33KK1168 pKa = 10.72ALTLCAGILGIATVTTLGVKK1188 pKa = 10.1LYY1190 pKa = 10.9RR1191 pKa = 11.84FLNPEE1196 pKa = 3.82NQANSAPDD1204 pKa = 3.56EE1205 pKa = 4.8DD1206 pKa = 5.74DD1207 pKa = 4.65PDD1209 pKa = 3.45SSYY1212 pKa = 11.91YY1213 pKa = 10.69KK1214 pKa = 10.4DD1215 pKa = 3.21ISHH1218 pKa = 7.15LKK1220 pKa = 9.33SGYY1223 pKa = 9.81RR1224 pKa = 11.84SALVKK1229 pKa = 10.33GDD1231 pKa = 4.59RR1232 pKa = 11.84IAMQNIYY1239 pKa = 9.95HH1240 pKa = 6.06QARR1243 pKa = 11.84QEE1245 pKa = 4.38GYY1247 pKa = 9.41SEE1249 pKa = 5.45KK1250 pKa = 10.68LNQWEE1255 pKa = 4.01HH1256 pKa = 6.12AFRR1259 pKa = 11.84SNSYY1263 pKa = 10.37LSRR1266 pKa = 11.84PKK1268 pKa = 10.63SEE1270 pKa = 3.78IEE1272 pKa = 3.69LMIRR1276 pKa = 11.84EE1277 pKa = 4.37SVNNQDD1283 pKa = 4.05LDD1285 pKa = 3.79SLAFFIKK1292 pKa = 10.3FDD1294 pKa = 4.36PDD1296 pKa = 3.56TVKK1299 pKa = 10.89SVLANKK1305 pKa = 10.63ANMLSIKK1312 pKa = 8.18EE1313 pKa = 4.53TQHH1316 pKa = 6.26QMPTLPQIWIEE1327 pKa = 4.0KK1328 pKa = 9.41LKK1330 pKa = 10.77RR1331 pKa = 11.84NYY1333 pKa = 10.35VLVINPITQAKK1344 pKa = 9.78VYY1346 pKa = 10.95ALGLRR1351 pKa = 11.84DD1352 pKa = 3.37KK1353 pKa = 10.5TAITVSHH1360 pKa = 7.2IFHH1363 pKa = 6.99KK1364 pKa = 10.96VGEE1367 pKa = 4.39TCIIQSDD1374 pKa = 4.1GKK1376 pKa = 10.54QYY1378 pKa = 10.94QAVCSALHH1386 pKa = 6.05RR1387 pKa = 11.84QRR1389 pKa = 11.84DD1390 pKa = 3.36MAMIQVIDD1398 pKa = 3.59KK1399 pKa = 10.08SFPSFRR1405 pKa = 11.84NMTSALVSHH1414 pKa = 6.41QDD1416 pKa = 3.14FGKK1419 pKa = 10.7FSTAWFVRR1427 pKa = 11.84PTDD1430 pKa = 3.31KK1431 pKa = 10.92PLIYY1435 pKa = 10.26SASTRR1440 pKa = 11.84FRR1442 pKa = 11.84GRR1444 pKa = 11.84SAFTMTDD1451 pKa = 3.11SNNPLYY1457 pKa = 10.12TLNHH1461 pKa = 6.61DD1462 pKa = 3.27FWEE1465 pKa = 4.33FHH1467 pKa = 6.9LIGMKK1472 pKa = 10.55DD1473 pKa = 3.35LTSTFSSGDD1482 pKa = 3.27CGFPLMAMFEE1492 pKa = 4.38NEE1494 pKa = 3.48WKK1496 pKa = 10.44IIGIHH1501 pKa = 5.66NSINGISSTGFFSSVSTEE1519 pKa = 3.88DD1520 pKa = 3.43LSNVSNSFSNKK1531 pKa = 8.06VPHH1534 pKa = 6.37MLDD1537 pKa = 3.49PEE1539 pKa = 4.35TGYY1542 pKa = 11.58VLDD1545 pKa = 3.8NSTYY1549 pKa = 10.44KK1550 pKa = 11.05ALTEE1554 pKa = 4.35GKK1556 pKa = 9.3WEE1558 pKa = 4.06DD1559 pKa = 3.15SKK1561 pKa = 11.76YY1562 pKa = 11.12AGVSPLQIIGRR1573 pKa = 11.84NASLHH1578 pKa = 4.86THH1580 pKa = 6.59SSPKK1584 pKa = 9.81HH1585 pKa = 5.2KK1586 pKa = 10.16KK1587 pKa = 9.77KK1588 pKa = 10.85YY1589 pKa = 10.12IPICEE1594 pKa = 4.98GILEE1598 pKa = 4.58CEE1600 pKa = 4.37TLPSALDD1607 pKa = 3.43MTHH1610 pKa = 6.69VKK1612 pKa = 9.15DD1613 pKa = 3.77TSKK1616 pKa = 11.27LIADD1620 pKa = 3.96KK1621 pKa = 10.95QGNYY1625 pKa = 9.79YY1626 pKa = 9.89PLFAQSVKK1634 pKa = 8.27YY1635 pKa = 8.84TKK1637 pKa = 9.34KK1638 pKa = 8.92TPTYY1642 pKa = 9.94GQFDD1646 pKa = 4.47LEE1648 pKa = 4.82LIEE1651 pKa = 5.43HH1652 pKa = 5.17VQEE1655 pKa = 5.18SIKK1658 pKa = 10.49QYY1660 pKa = 11.08YY1661 pKa = 9.39DD1662 pKa = 2.94MHH1664 pKa = 7.92YY1665 pKa = 11.2GDD1667 pKa = 4.37AHH1669 pKa = 5.07QLRR1672 pKa = 11.84LRR1674 pKa = 11.84EE1675 pKa = 4.14VINGYY1680 pKa = 10.19EE1681 pKa = 4.02NVQPFDD1687 pKa = 3.87MTTSAGPKK1695 pKa = 7.94MKK1697 pKa = 9.79RR1698 pKa = 11.84DD1699 pKa = 3.54FGINVKK1705 pKa = 8.92MPKK1708 pKa = 9.23TGQSDD1713 pKa = 3.71ILFTNCNADD1722 pKa = 4.04DD1723 pKa = 4.08PQKK1726 pKa = 11.15KK1727 pKa = 9.25PFYY1730 pKa = 10.64VINTKK1735 pKa = 9.71TNAGNALMQDD1745 pKa = 3.45FHH1747 pKa = 9.08HH1748 pKa = 6.53YY1749 pKa = 9.27MSAIEE1754 pKa = 4.71AGDD1757 pKa = 4.5PILLVIKK1764 pKa = 10.54DD1765 pKa = 3.71NAKK1768 pKa = 10.35VEE1770 pKa = 4.44LLPKK1774 pKa = 10.69DD1775 pKa = 3.38KK1776 pKa = 11.44VEE1778 pKa = 4.07EE1779 pKa = 4.35GKK1781 pKa = 10.46VRR1783 pKa = 11.84LFNEE1787 pKa = 3.77MDD1789 pKa = 3.6LSVNMVLKK1797 pKa = 10.58SYY1799 pKa = 10.91FGGFLNSIIEE1809 pKa = 4.11KK1810 pKa = 9.78HH1811 pKa = 6.0HH1812 pKa = 6.02EE1813 pKa = 3.95CMYY1816 pKa = 10.59TIGFNPYY1823 pKa = 9.97KK1824 pKa = 10.38EE1825 pKa = 4.55ATLHH1829 pKa = 6.15MLDD1832 pKa = 4.29FNLIDD1837 pKa = 3.88GVVVSSDD1844 pKa = 3.33YY1845 pKa = 11.6SGLDD1849 pKa = 2.88KK1850 pKa = 11.2SFPKK1854 pKa = 10.42EE1855 pKa = 3.89LITGFVEE1862 pKa = 4.3AVSRR1866 pKa = 11.84GKK1868 pKa = 9.17WSKK1871 pKa = 9.93EE1872 pKa = 3.5VEE1874 pKa = 4.21TALSKK1879 pKa = 9.87TLTYY1883 pKa = 9.76TYY1885 pKa = 10.65HH1886 pKa = 6.89SINGHH1891 pKa = 6.69IYY1893 pKa = 10.23PVDD1896 pKa = 3.94CGNEE1900 pKa = 3.88SGSYY1904 pKa = 6.96VTTMINCYY1912 pKa = 9.85AVHH1915 pKa = 6.09FVNWYY1920 pKa = 6.88TFARR1924 pKa = 11.84KK1925 pKa = 8.11WRR1927 pKa = 11.84EE1928 pKa = 3.8TYY1930 pKa = 11.05NIMPSLKK1937 pKa = 10.51DD1938 pKa = 3.63FEE1940 pKa = 6.56DD1941 pKa = 3.79NFCQKK1946 pKa = 10.34ILGDD1950 pKa = 3.54DD1951 pKa = 4.74CIRR1954 pKa = 11.84KK1955 pKa = 9.08ISYY1958 pKa = 9.38RR1959 pKa = 11.84VKK1961 pKa = 10.35IDD1963 pKa = 3.54FDD1965 pKa = 4.61DD1966 pKa = 4.3LAKK1969 pKa = 10.8DD1970 pKa = 3.18AALFNLTLTKK1980 pKa = 10.31PKK1982 pKa = 10.14IEE1984 pKa = 4.34GEE1986 pKa = 3.72ISFCSRR1992 pKa = 11.84VYY1994 pKa = 11.46KK1995 pKa = 10.01MIRR1998 pKa = 11.84PNIYY2002 pKa = 10.36APCLKK2007 pKa = 9.3TASITSCLFYY2017 pKa = 10.73LASEE2021 pKa = 4.33TKK2023 pKa = 10.11EE2024 pKa = 3.82QISMNINIALFEE2036 pKa = 4.5ASLHH2040 pKa = 5.55GKK2042 pKa = 9.18EE2043 pKa = 5.73FFDD2046 pKa = 4.36QVAKK2050 pKa = 10.55AALAIAKK2057 pKa = 9.31HH2058 pKa = 4.92YY2059 pKa = 10.8NITIDD2064 pKa = 4.6LYY2066 pKa = 9.8PHH2068 pKa = 6.84KK2069 pKa = 10.57CYY2071 pKa = 9.77IDD2073 pKa = 3.82YY2074 pKa = 10.9FIGYY2078 pKa = 8.34VLNEE2082 pKa = 4.49SKK2084 pKa = 10.94HH2085 pKa = 5.45PTLQAAGSLSTQLIEE2100 pKa = 5.76SNSQDD2105 pKa = 3.4YY2106 pKa = 11.03SPQNIIQKK2114 pKa = 10.04QKK2116 pKa = 8.57FNKK2119 pKa = 8.76MADD2122 pKa = 2.99MWLNEE2127 pKa = 3.98YY2128 pKa = 10.04VQAQRR2133 pKa = 11.84LEE2135 pKa = 4.52TPVYY2139 pKa = 8.63TYY2141 pKa = 11.77SMDD2144 pKa = 5.04GKK2146 pKa = 8.65TEE2148 pKa = 3.7WDD2150 pKa = 3.58VEE2152 pKa = 4.46VLLKK2156 pKa = 10.68HH2157 pKa = 6.86HH2158 pKa = 6.52EE2159 pKa = 4.04NQYY2162 pKa = 9.25RR2163 pKa = 11.84AKK2165 pKa = 10.09GHH2167 pKa = 6.05GRR2169 pKa = 11.84TKK2171 pKa = 10.58QDD2173 pKa = 3.38AKK2175 pKa = 10.76RR2176 pKa = 11.84AACKK2180 pKa = 9.13QLKK2183 pKa = 8.68ATLTNFTRR2191 pKa = 11.84NIGSLRR2197 pKa = 11.84IGKK2200 pKa = 8.18IQRR2203 pKa = 11.84EE2204 pKa = 4.28LTEE2207 pKa = 4.37SDD2209 pKa = 3.31MEE2211 pKa = 4.23AVIGMFMKK2219 pKa = 10.58HH2220 pKa = 6.17FNIKK2224 pKa = 10.61DD2225 pKa = 3.48DD2226 pKa = 4.32DD2227 pKa = 4.25FEE2229 pKa = 4.37ITIGTTNQANADD2241 pKa = 3.99TPMEE2245 pKa = 4.52PATMNQASRR2254 pKa = 11.84FQGEE2258 pKa = 4.07GSLPGNANPQPTAVVPAMTSSGEE2281 pKa = 4.17DD2282 pKa = 2.87IQAAIMGQEE2291 pKa = 3.85QHH2293 pKa = 5.77TLNPIGAPDD2302 pKa = 3.91MSTVGAIQFDD2312 pKa = 4.55LKK2314 pKa = 11.16DD2315 pKa = 3.22LAYY2318 pKa = 10.51QQFLDD2323 pKa = 3.92ADD2325 pKa = 4.06TEE2327 pKa = 4.5IEE2329 pKa = 4.33VSADD2333 pKa = 3.32MPAGTVVAQIPYY2345 pKa = 8.88GWNHH2349 pKa = 6.58PFLNRR2354 pKa = 11.84YY2355 pKa = 7.56AKK2357 pKa = 10.19RR2358 pKa = 11.84WVQQHH2363 pKa = 4.96EE2364 pKa = 4.81RR2365 pKa = 11.84YY2366 pKa = 8.16TGSFKK2371 pKa = 10.8YY2372 pKa = 10.15RR2373 pKa = 11.84YY2374 pKa = 7.17TVIGNPLFSGAIGIAWVKK2392 pKa = 10.62KK2393 pKa = 10.26RR2394 pKa = 11.84ITTSIVPVSMMQKK2407 pKa = 9.54YY2408 pKa = 9.68SYY2410 pKa = 9.38SAKK2413 pKa = 9.94GVTMPWNVIHH2423 pKa = 6.53TLHH2426 pKa = 7.47DD2427 pKa = 3.23ARR2429 pKa = 11.84KK2430 pKa = 7.96QYY2432 pKa = 10.58FYY2434 pKa = 11.43RR2435 pKa = 11.84EE2436 pKa = 4.19VEE2438 pKa = 4.86DD2439 pKa = 6.44DD2440 pKa = 5.07LDD2442 pKa = 5.27DD2443 pKa = 6.32DD2444 pKa = 4.36NLADD2448 pKa = 4.51RR2449 pKa = 11.84PHH2451 pKa = 6.84LVLFLLMSLQNPLQPGVITRR2471 pKa = 11.84VRR2473 pKa = 11.84IASKK2477 pKa = 10.28LATVGEE2483 pKa = 4.55GNPFRR2488 pKa = 11.84ALDD2491 pKa = 3.97PADD2494 pKa = 3.84TDD2496 pKa = 3.98TAPEE2500 pKa = 4.26TTTTPVPQNRR2510 pKa = 11.84FQSVFPQDD2518 pKa = 3.29LNKK2521 pKa = 10.49RR2522 pKa = 11.84IWLYY2526 pKa = 11.07TDD2528 pKa = 3.72GQLSASTNPTMEE2540 pKa = 4.57AYY2542 pKa = 9.74YY2543 pKa = 10.35PDD2545 pKa = 4.25MIYY2548 pKa = 10.37EE2549 pKa = 3.98ARR2551 pKa = 11.84KK2552 pKa = 9.55NGIIGGQVGGTDD2564 pKa = 3.83PNDD2567 pKa = 2.95LSTYY2571 pKa = 10.3YY2572 pKa = 10.6NVEE2575 pKa = 3.0NWARR2579 pKa = 11.84TDD2581 pKa = 3.21TVTNLTADD2589 pKa = 4.06WPWMSGKK2596 pKa = 10.04SVSPGDD2602 pKa = 3.67YY2603 pKa = 7.57VTVYY2607 pKa = 8.95ITTVTNMDD2615 pKa = 3.34QKK2617 pKa = 11.51SFYY2620 pKa = 11.47AWINNNNWAGFQKK2633 pKa = 10.6QPGGNTMTWNKK2644 pKa = 8.71WNANKK2649 pKa = 10.51GYY2651 pKa = 10.62LPAPQLAGGVLTHH2664 pKa = 6.9SSTYY2668 pKa = 10.5NQTEE2672 pKa = 4.31LKK2674 pKa = 10.43FSTNASLGYY2683 pKa = 10.45GFSNTIKK2690 pKa = 10.29EE2691 pKa = 4.22WIKK2694 pKa = 10.7YY2695 pKa = 6.74VTDD2698 pKa = 3.17KK2699 pKa = 10.68GTIYY2703 pKa = 10.77FLLCYY2708 pKa = 8.57TEE2710 pKa = 3.98QMRR2713 pKa = 11.84GIAATPYY2720 pKa = 8.21PRR2722 pKa = 11.84QVASRR2727 pKa = 11.84FAGHH2731 pKa = 6.03YY2732 pKa = 7.07QTQTVQNLPQYY2743 pKa = 10.38PIFNVDD2749 pKa = 3.27EE2750 pKa = 4.09QLGSIRR2756 pKa = 11.84GNINTLPSGNLLFRR2770 pKa = 11.84MTEE2773 pKa = 3.93MPPSSVAVGQAQMPTCSDD2791 pKa = 3.02NATIAKK2797 pKa = 9.45YY2798 pKa = 9.6FALLSQGLATLQCLQFRR2815 pKa = 11.84LIDD2818 pKa = 3.97AQSVRR2823 pKa = 11.84QIATVRR2829 pKa = 11.84YY2830 pKa = 8.07LQEE2833 pKa = 3.82SQVFVINAPNSPTRR2847 pKa = 11.84YY2848 pKa = 9.11RR2849 pKa = 11.84VVPQNNEE2856 pKa = 3.86NIIIGQITVVQRR2868 pKa = 11.84ATDD2871 pKa = 3.71FQEE2874 pKa = 4.07TVTFDD2879 pKa = 2.76WTDD2882 pKa = 3.17RR2883 pKa = 11.84VAPEE2887 pKa = 3.52FLRR2890 pKa = 11.84RR2891 pKa = 11.84GDD2893 pKa = 3.64VFKK2896 pKa = 10.19TAISPDD2902 pKa = 3.65LFSDD2906 pKa = 3.69VTPQKK2911 pKa = 10.92DD2912 pKa = 3.75GYY2914 pKa = 8.0TANATLLASMAGGALGGIGQAIGQHH2939 pKa = 5.14QNRR2942 pKa = 11.84KK2943 pKa = 8.9HH2944 pKa = 5.35EE2945 pKa = 5.12KK2946 pKa = 9.95EE2947 pKa = 3.89MQSNQFGHH2955 pKa = 6.59EE2956 pKa = 3.86EE2957 pKa = 4.07TMQGNMFNFQNQFQQQGFDD2976 pKa = 3.71FQKK2979 pKa = 10.35MMQEE2983 pKa = 4.01NQFGFQNKK2991 pKa = 8.39YY2992 pKa = 7.99QAQQHH2997 pKa = 4.98YY2998 pKa = 10.11QEE3000 pKa = 4.49QLLQEE3005 pKa = 4.16RR3006 pKa = 11.84GYY3008 pKa = 11.3QNDD3011 pKa = 3.74LGLLQSSHH3019 pKa = 4.94QEE3021 pKa = 3.47QRR3023 pKa = 11.84ITNKK3027 pKa = 9.54EE3028 pKa = 3.73QSHH3031 pKa = 5.39NRR3033 pKa = 11.84MTEE3036 pKa = 3.61RR3037 pKa = 11.84GLSSRR3042 pKa = 11.84VMGMPGAVTSASSAA3056 pKa = 3.33

Molecular weight: 344.33 kDa
Isoelectric point according different methods:

>tr|A0A1L3KKP0|A0A1L3KKP0_9VIRU RdRP_1 domain-containing protein OS=Hubei picorna-like virus 60 OX=1923143 PE=4 SV=1
MM1 pKa = 7.52QNNNNNKK8 pKa = 9.23PCDD11 pKa = 3.75ALKK14 pKa = 10.74CALRR18 pKa = 11.84EE19 pKa = 3.76QADD22 pKa = 4.03PVRR25 pKa = 11.84HH26 pKa = 5.96LVDD29 pKa = 3.1AHH31 pKa = 6.34KK32 pKa = 10.33IKK34 pKa = 10.36PFSYY38 pKa = 10.65EE39 pKa = 3.62EE40 pKa = 4.02VSMVKK45 pKa = 10.5ANNITSPCFFEE56 pKa = 4.8LLATIRR62 pKa = 11.84PLTFPSPQAAQQFVYY77 pKa = 10.87NVVADD82 pKa = 3.99SYY84 pKa = 9.81TDD86 pKa = 3.33KK87 pKa = 11.14RR88 pKa = 11.84SGGQPSARR96 pKa = 11.84DD97 pKa = 3.41NFTKK101 pKa = 10.53RR102 pKa = 11.84FFAKK106 pKa = 10.44DD107 pKa = 3.35GTGGMQFDD115 pKa = 4.84DD116 pKa = 4.58LDD118 pKa = 3.97VVARR122 pKa = 11.84ALNCTFAVCATKK134 pKa = 10.15IPKK137 pKa = 9.59QNSRR141 pKa = 11.84GTNTKK146 pKa = 9.8YY147 pKa = 9.25FTIGHH152 pKa = 5.36SPEE155 pKa = 3.5RR156 pKa = 11.84VYY158 pKa = 10.92IKK160 pKa = 9.53WVYY163 pKa = 7.82NHH165 pKa = 7.41HH166 pKa = 6.0YY167 pKa = 10.52QLIKK171 pKa = 10.55PIDD174 pKa = 3.99DD175 pKa = 3.89TTSSSTMSDD184 pKa = 3.49DD185 pKa = 3.88EE186 pKa = 4.26EE187 pKa = 6.12APLIRR192 pKa = 11.84YY193 pKa = 6.78QTHH196 pKa = 7.05PNNTLNGKK204 pKa = 8.69PEE206 pKa = 3.82QPQDD210 pKa = 3.51EE211 pKa = 4.68FKK213 pKa = 10.06KK214 pKa = 9.17TVMNTPCAFTKK225 pKa = 10.54KK226 pKa = 8.91KK227 pKa = 8.56TLQSLTPPSSTTPTISEE244 pKa = 4.18DD245 pKa = 3.38EE246 pKa = 4.28EE247 pKa = 4.9EE248 pKa = 4.45IVSAVNLIRR257 pKa = 11.84EE258 pKa = 4.37HH259 pKa = 6.21LLKK262 pKa = 10.99DD263 pKa = 3.91FFPGLDD269 pKa = 3.26THH271 pKa = 6.82VKK273 pKa = 9.43VAVATSIAASIVSVSANISALIGGKK298 pKa = 9.87LGPINKK304 pKa = 9.06AVQIASIVTSLTSFTSNVSLALRR327 pKa = 11.84ANEE330 pKa = 4.05IKK332 pKa = 10.9FNFDD336 pKa = 2.67KK337 pKa = 11.29VMNSIPGLASTLHH350 pKa = 5.79STFKK354 pKa = 10.91ANSAAWIYY362 pKa = 7.52PTISALVSLIIGGLTIFNVSDD383 pKa = 3.09IKK385 pKa = 11.08EE386 pKa = 4.21VIQAGSLLKK395 pKa = 9.95TINAFGTEE403 pKa = 4.02AKK405 pKa = 10.65NITKK409 pKa = 10.33YY410 pKa = 10.9VLEE413 pKa = 5.19DD414 pKa = 3.75LLEE417 pKa = 5.59LDD419 pKa = 3.54VTGDD423 pKa = 4.38HH424 pKa = 6.55IQHH427 pKa = 6.92KK428 pKa = 10.45ALIDD432 pKa = 3.49MAKK435 pKa = 10.03RR436 pKa = 11.84SAEE439 pKa = 4.06LCVMPHH445 pKa = 5.75YY446 pKa = 10.89KK447 pKa = 10.52FFGDD451 pKa = 3.58PGLLQEE457 pKa = 5.08LKK459 pKa = 10.72SISEE463 pKa = 4.25KK464 pKa = 10.57ATDD467 pKa = 3.53LTAKK471 pKa = 10.32KK472 pKa = 9.44FANPKK477 pKa = 7.47TSQVARR483 pKa = 11.84MASQTLMHH491 pKa = 6.62NVAQLQEE498 pKa = 4.22KK499 pKa = 9.07EE500 pKa = 3.88LAIRR504 pKa = 11.84TVFDD508 pKa = 3.73ASARR512 pKa = 11.84QEE514 pKa = 4.26TFGVLLAGAPSIGKK528 pKa = 9.85SYY530 pKa = 11.28LLTQIWAKK538 pKa = 10.25LSPIFGYY545 pKa = 10.59KK546 pKa = 9.19PDD548 pKa = 4.71LYY550 pKa = 10.89NLTISRR556 pKa = 11.84SDD558 pKa = 3.48GFFEE562 pKa = 4.77PYY564 pKa = 10.83GMQDD568 pKa = 2.88CGFVNEE574 pKa = 4.49FMGSRR579 pKa = 11.84EE580 pKa = 4.06DD581 pKa = 4.77AFLTHH586 pKa = 6.87LNSTISADD594 pKa = 3.64PKK596 pKa = 9.63NLEE599 pKa = 3.81GAFQKK604 pKa = 10.37SQPAQFKK611 pKa = 10.87LVFLTSNDD619 pKa = 3.01IAPEE623 pKa = 4.1LTRR626 pKa = 11.84HH627 pKa = 5.4LTDD630 pKa = 3.26SAAKK634 pKa = 10.04AVWNRR639 pKa = 11.84ILRR642 pKa = 11.84IQVEE646 pKa = 4.31DD647 pKa = 4.19PKK649 pKa = 11.17CQGRR653 pKa = 11.84QGINTHH659 pKa = 5.43RR660 pKa = 11.84RR661 pKa = 11.84ADD663 pKa = 4.1FSHH666 pKa = 6.21LTIKK670 pKa = 10.62KK671 pKa = 10.31VMDD674 pKa = 3.52TEE676 pKa = 4.33ALSKK680 pKa = 10.69EE681 pKa = 3.85RR682 pKa = 11.84TLNSLQTITLDD693 pKa = 3.51SLIVEE698 pKa = 4.8IAHH701 pKa = 4.76QVARR705 pKa = 11.84RR706 pKa = 11.84EE707 pKa = 3.91KK708 pKa = 10.25RR709 pKa = 11.84YY710 pKa = 9.5LQSIVNNDD718 pKa = 2.7IFNNEE723 pKa = 3.6QEE725 pKa = 4.82DD726 pKa = 3.42IRR728 pKa = 11.84KK729 pKa = 9.86RR730 pKa = 11.84IARR733 pKa = 11.84LDD735 pKa = 3.91EE736 pKa = 4.67IMATTNWANAEE747 pKa = 4.0GGNTYY752 pKa = 10.76NIIRR756 pKa = 11.84LQGPLEE762 pKa = 4.15TGKK765 pKa = 8.63TEE767 pKa = 4.19LAKK770 pKa = 10.81EE771 pKa = 3.71MAAAITSVYY780 pKa = 10.07YY781 pKa = 10.48KK782 pKa = 10.32RR783 pKa = 11.84EE784 pKa = 4.01LVIITQPSQFLEE796 pKa = 4.53KK797 pKa = 9.93PSKK800 pKa = 10.79HH801 pKa = 5.53PMVYY805 pKa = 10.74LLDD808 pKa = 4.4DD809 pKa = 3.95VVDD812 pKa = 3.99EE813 pKa = 4.69TTHH816 pKa = 6.3NDD818 pKa = 2.92YY819 pKa = 11.03FKK821 pKa = 10.55WINSCNSEE829 pKa = 4.2SLFIITSNKK838 pKa = 10.04SYY840 pKa = 10.35TRR842 pKa = 11.84TLTTQAWLKK851 pKa = 9.61TKK853 pKa = 10.28ALNVFGFAGEE863 pKa = 4.37EE864 pKa = 3.69EE865 pKa = 4.45HH866 pKa = 7.43FYY868 pKa = 10.73IDD870 pKa = 3.37TQHH873 pKa = 5.09THH875 pKa = 5.76SGIARR880 pKa = 11.84RR881 pKa = 11.84LGLYY885 pKa = 10.33GRR887 pKa = 11.84VDD889 pKa = 4.95AITEE893 pKa = 4.05KK894 pKa = 11.01GIEE897 pKa = 4.28TVVNDD902 pKa = 4.49PSMHH906 pKa = 5.09MTIDD910 pKa = 3.45ATPGFQYY917 pKa = 10.26TINGTPIMPEE927 pKa = 3.88DD928 pKa = 3.81LKK930 pKa = 10.96QHH932 pKa = 5.35VFRR935 pKa = 11.84TYY937 pKa = 8.97TAFIAKK943 pKa = 7.99SHH945 pKa = 6.99KK946 pKa = 10.11IQVLNSTYY954 pKa = 11.06SNPTQEE960 pKa = 4.38YY961 pKa = 9.5DD962 pKa = 3.79VKK964 pKa = 10.31ITADD968 pKa = 5.05DD969 pKa = 3.53IDD971 pKa = 3.78SLYY974 pKa = 11.29NAFSNITNITSLLFFGAKK992 pKa = 8.81GASVTISKK1000 pKa = 10.34RR1001 pKa = 11.84VMVAIPRR1008 pKa = 11.84DD1009 pKa = 3.69MHH1011 pKa = 6.95DD1012 pKa = 3.53ATALIPNKK1020 pKa = 10.07KK1021 pKa = 10.21LEE1023 pKa = 4.09TRR1025 pKa = 11.84EE1026 pKa = 3.98EE1027 pKa = 4.32VISLAKK1033 pKa = 10.43RR1034 pKa = 11.84LGAFMAKK1041 pKa = 10.29LIPDD1045 pKa = 3.71IKK1047 pKa = 10.43IYY1049 pKa = 10.32FHH1051 pKa = 7.24LAGQPPIVLIDD1062 pKa = 3.38KK1063 pKa = 10.36QLFIGAHH1070 pKa = 4.88EE1071 pKa = 4.27TLSIDD1076 pKa = 3.34IVRR1079 pKa = 11.84SSDD1082 pKa = 2.91AFHH1085 pKa = 6.75WVFQGRR1091 pKa = 11.84AHH1093 pKa = 7.86RR1094 pKa = 11.84LRR1096 pKa = 11.84DD1097 pKa = 3.13EE1098 pKa = 4.76DD1099 pKa = 3.97FALFTSTGVLPPAMQEE1115 pKa = 3.85LPQFIIAAIVAKK1127 pKa = 9.1YY1128 pKa = 10.54ASMRR1132 pKa = 11.84KK1133 pKa = 9.42EE1134 pKa = 3.8EE1135 pKa = 4.21TPLIRR1140 pKa = 11.84TWIEE1144 pKa = 3.52HH1145 pKa = 4.87YY1146 pKa = 10.32KK1147 pKa = 8.76IEE1149 pKa = 5.23RR1150 pKa = 11.84MIRR1153 pKa = 11.84DD1154 pKa = 3.53YY1155 pKa = 11.27KK1156 pKa = 10.98EE1157 pKa = 4.23RR1158 pKa = 11.84GLLSFLFEE1166 pKa = 4.61HH1167 pKa = 7.33KK1168 pKa = 10.72ALTLCAGILGIATVTTLGVKK1188 pKa = 10.1LYY1190 pKa = 10.9RR1191 pKa = 11.84FLNPEE1196 pKa = 3.82NQANSAPDD1204 pKa = 3.56EE1205 pKa = 4.8DD1206 pKa = 5.74DD1207 pKa = 4.65PDD1209 pKa = 3.45SSYY1212 pKa = 11.91YY1213 pKa = 10.69KK1214 pKa = 10.4DD1215 pKa = 3.21ISHH1218 pKa = 7.15LKK1220 pKa = 9.33SGYY1223 pKa = 9.81RR1224 pKa = 11.84SALVKK1229 pKa = 10.33GDD1231 pKa = 4.59RR1232 pKa = 11.84IAMQNIYY1239 pKa = 9.95HH1240 pKa = 6.06QARR1243 pKa = 11.84QEE1245 pKa = 4.38GYY1247 pKa = 9.41SEE1249 pKa = 5.45KK1250 pKa = 10.68LNQWEE1255 pKa = 4.01HH1256 pKa = 6.12AFRR1259 pKa = 11.84SNSYY1263 pKa = 10.37LSRR1266 pKa = 11.84PKK1268 pKa = 10.63SEE1270 pKa = 3.78IEE1272 pKa = 3.69LMIRR1276 pKa = 11.84EE1277 pKa = 4.37SVNNQDD1283 pKa = 4.05LDD1285 pKa = 3.79SLAFFIKK1292 pKa = 10.3FDD1294 pKa = 4.36PDD1296 pKa = 3.56TVKK1299 pKa = 10.89SVLANKK1305 pKa = 10.63ANMLSIKK1312 pKa = 8.18EE1313 pKa = 4.53TQHH1316 pKa = 6.26QMPTLPQIWIEE1327 pKa = 4.0KK1328 pKa = 9.41LKK1330 pKa = 10.77RR1331 pKa = 11.84NYY1333 pKa = 10.35VLVINPITQAKK1344 pKa = 9.78VYY1346 pKa = 10.95ALGLRR1351 pKa = 11.84DD1352 pKa = 3.37KK1353 pKa = 10.5TAITVSHH1360 pKa = 7.2IFHH1363 pKa = 6.99KK1364 pKa = 10.96VGEE1367 pKa = 4.39TCIIQSDD1374 pKa = 4.1GKK1376 pKa = 10.54QYY1378 pKa = 10.94QAVCSALHH1386 pKa = 6.05RR1387 pKa = 11.84QRR1389 pKa = 11.84DD1390 pKa = 3.36MAMIQVIDD1398 pKa = 3.59KK1399 pKa = 10.08SFPSFRR1405 pKa = 11.84NMTSALVSHH1414 pKa = 6.41QDD1416 pKa = 3.14FGKK1419 pKa = 10.7FSTAWFVRR1427 pKa = 11.84PTDD1430 pKa = 3.31KK1431 pKa = 10.92PLIYY1435 pKa = 10.26SASTRR1440 pKa = 11.84FRR1442 pKa = 11.84GRR1444 pKa = 11.84SAFTMTDD1451 pKa = 3.11SNNPLYY1457 pKa = 10.12TLNHH1461 pKa = 6.61DD1462 pKa = 3.27FWEE1465 pKa = 4.33FHH1467 pKa = 6.9LIGMKK1472 pKa = 10.55DD1473 pKa = 3.35LTSTFSSGDD1482 pKa = 3.27CGFPLMAMFEE1492 pKa = 4.38NEE1494 pKa = 3.48WKK1496 pKa = 10.44IIGIHH1501 pKa = 5.66NSINGISSTGFFSSVSTEE1519 pKa = 3.88DD1520 pKa = 3.43LSNVSNSFSNKK1531 pKa = 8.06VPHH1534 pKa = 6.37MLDD1537 pKa = 3.49PEE1539 pKa = 4.35TGYY1542 pKa = 11.58VLDD1545 pKa = 3.8NSTYY1549 pKa = 10.44KK1550 pKa = 11.05ALTEE1554 pKa = 4.35GKK1556 pKa = 9.3WEE1558 pKa = 4.06DD1559 pKa = 3.15SKK1561 pKa = 11.76YY1562 pKa = 11.12AGVSPLQIIGRR1573 pKa = 11.84NASLHH1578 pKa = 4.86THH1580 pKa = 6.59SSPKK1584 pKa = 9.81HH1585 pKa = 5.2KK1586 pKa = 10.16KK1587 pKa = 9.77KK1588 pKa = 10.85YY1589 pKa = 10.12IPICEE1594 pKa = 4.98GILEE1598 pKa = 4.58CEE1600 pKa = 4.37TLPSALDD1607 pKa = 3.43MTHH1610 pKa = 6.69VKK1612 pKa = 9.15DD1613 pKa = 3.77TSKK1616 pKa = 11.27LIADD1620 pKa = 3.96KK1621 pKa = 10.95QGNYY1625 pKa = 9.79YY1626 pKa = 9.89PLFAQSVKK1634 pKa = 8.27YY1635 pKa = 8.84TKK1637 pKa = 9.34KK1638 pKa = 8.92TPTYY1642 pKa = 9.94GQFDD1646 pKa = 4.47LEE1648 pKa = 4.82LIEE1651 pKa = 5.43HH1652 pKa = 5.17VQEE1655 pKa = 5.18SIKK1658 pKa = 10.49QYY1660 pKa = 11.08YY1661 pKa = 9.39DD1662 pKa = 2.94MHH1664 pKa = 7.92YY1665 pKa = 11.2GDD1667 pKa = 4.37AHH1669 pKa = 5.07QLRR1672 pKa = 11.84LRR1674 pKa = 11.84EE1675 pKa = 4.14VINGYY1680 pKa = 10.19EE1681 pKa = 4.02NVQPFDD1687 pKa = 3.87MTTSAGPKK1695 pKa = 7.94MKK1697 pKa = 9.79RR1698 pKa = 11.84DD1699 pKa = 3.54FGINVKK1705 pKa = 8.92MPKK1708 pKa = 9.23TGQSDD1713 pKa = 3.71ILFTNCNADD1722 pKa = 4.04DD1723 pKa = 4.08PQKK1726 pKa = 11.15KK1727 pKa = 9.25PFYY1730 pKa = 10.64VINTKK1735 pKa = 9.71TNAGNALMQDD1745 pKa = 3.45FHH1747 pKa = 9.08HH1748 pKa = 6.53YY1749 pKa = 9.27MSAIEE1754 pKa = 4.71AGDD1757 pKa = 4.5PILLVIKK1764 pKa = 10.54DD1765 pKa = 3.71NAKK1768 pKa = 10.35VEE1770 pKa = 4.44LLPKK1774 pKa = 10.69DD1775 pKa = 3.38KK1776 pKa = 11.44VEE1778 pKa = 4.07EE1779 pKa = 4.35GKK1781 pKa = 10.46VRR1783 pKa = 11.84LFNEE1787 pKa = 3.77MDD1789 pKa = 3.6LSVNMVLKK1797 pKa = 10.58SYY1799 pKa = 10.91FGGFLNSIIEE1809 pKa = 4.11KK1810 pKa = 9.78HH1811 pKa = 6.0HH1812 pKa = 6.02EE1813 pKa = 3.95CMYY1816 pKa = 10.59TIGFNPYY1823 pKa = 9.97KK1824 pKa = 10.38EE1825 pKa = 4.55ATLHH1829 pKa = 6.15MLDD1832 pKa = 4.29FNLIDD1837 pKa = 3.88GVVVSSDD1844 pKa = 3.33YY1845 pKa = 11.6SGLDD1849 pKa = 2.88KK1850 pKa = 11.2SFPKK1854 pKa = 10.42EE1855 pKa = 3.89LITGFVEE1862 pKa = 4.3AVSRR1866 pKa = 11.84GKK1868 pKa = 9.17WSKK1871 pKa = 9.93EE1872 pKa = 3.5VEE1874 pKa = 4.21TALSKK1879 pKa = 9.87TLTYY1883 pKa = 9.76TYY1885 pKa = 10.65HH1886 pKa = 6.89SINGHH1891 pKa = 6.69IYY1893 pKa = 10.23PVDD1896 pKa = 3.94CGNEE1900 pKa = 3.88SGSYY1904 pKa = 6.96VTTMINCYY1912 pKa = 9.85AVHH1915 pKa = 6.09FVNWYY1920 pKa = 6.88TFARR1924 pKa = 11.84KK1925 pKa = 8.11WRR1927 pKa = 11.84EE1928 pKa = 3.8TYY1930 pKa = 11.05NIMPSLKK1937 pKa = 10.51DD1938 pKa = 3.63FEE1940 pKa = 6.56DD1941 pKa = 3.79NFCQKK1946 pKa = 10.34ILGDD1950 pKa = 3.54DD1951 pKa = 4.74CIRR1954 pKa = 11.84KK1955 pKa = 9.08ISYY1958 pKa = 9.38RR1959 pKa = 11.84VKK1961 pKa = 10.35IDD1963 pKa = 3.54FDD1965 pKa = 4.61DD1966 pKa = 4.3LAKK1969 pKa = 10.8DD1970 pKa = 3.18AALFNLTLTKK1980 pKa = 10.31PKK1982 pKa = 10.14IEE1984 pKa = 4.34GEE1986 pKa = 3.72ISFCSRR1992 pKa = 11.84VYY1994 pKa = 11.46KK1995 pKa = 10.01MIRR1998 pKa = 11.84PNIYY2002 pKa = 10.36APCLKK2007 pKa = 9.3TASITSCLFYY2017 pKa = 10.73LASEE2021 pKa = 4.33TKK2023 pKa = 10.11EE2024 pKa = 3.82QISMNINIALFEE2036 pKa = 4.5ASLHH2040 pKa = 5.55GKK2042 pKa = 9.18EE2043 pKa = 5.73FFDD2046 pKa = 4.36QVAKK2050 pKa = 10.55AALAIAKK2057 pKa = 9.31HH2058 pKa = 4.92YY2059 pKa = 10.8NITIDD2064 pKa = 4.6LYY2066 pKa = 9.8PHH2068 pKa = 6.84KK2069 pKa = 10.57CYY2071 pKa = 9.77IDD2073 pKa = 3.82YY2074 pKa = 10.9FIGYY2078 pKa = 8.34VLNEE2082 pKa = 4.49SKK2084 pKa = 10.94HH2085 pKa = 5.45PTLQAAGSLSTQLIEE2100 pKa = 5.76SNSQDD2105 pKa = 3.4YY2106 pKa = 11.03SPQNIIQKK2114 pKa = 10.04QKK2116 pKa = 8.57FNKK2119 pKa = 8.76MADD2122 pKa = 2.99MWLNEE2127 pKa = 3.98YY2128 pKa = 10.04VQAQRR2133 pKa = 11.84LEE2135 pKa = 4.52TPVYY2139 pKa = 8.63TYY2141 pKa = 11.77SMDD2144 pKa = 5.04GKK2146 pKa = 8.65TEE2148 pKa = 3.7WDD2150 pKa = 3.58VEE2152 pKa = 4.46VLLKK2156 pKa = 10.68HH2157 pKa = 6.86HH2158 pKa = 6.52EE2159 pKa = 4.04NQYY2162 pKa = 9.25RR2163 pKa = 11.84AKK2165 pKa = 10.09GHH2167 pKa = 6.05GRR2169 pKa = 11.84TKK2171 pKa = 10.58QDD2173 pKa = 3.38AKK2175 pKa = 10.76RR2176 pKa = 11.84AACKK2180 pKa = 9.13QLKK2183 pKa = 8.68ATLTNFTRR2191 pKa = 11.84NIGSLRR2197 pKa = 11.84IGKK2200 pKa = 8.18IQRR2203 pKa = 11.84EE2204 pKa = 4.28LTEE2207 pKa = 4.37SDD2209 pKa = 3.31MEE2211 pKa = 4.23AVIGMFMKK2219 pKa = 10.58HH2220 pKa = 6.17FNIKK2224 pKa = 10.61DD2225 pKa = 3.48DD2226 pKa = 4.32DD2227 pKa = 4.25FEE2229 pKa = 4.37ITIGTTNQANADD2241 pKa = 3.99TPMEE2245 pKa = 4.52PATMNQASRR2254 pKa = 11.84FQGEE2258 pKa = 4.07GSLPGNANPQPTAVVPAMTSSGEE2281 pKa = 4.17DD2282 pKa = 2.87IQAAIMGQEE2291 pKa = 3.85QHH2293 pKa = 5.77TLNPIGAPDD2302 pKa = 3.91MSTVGAIQFDD2312 pKa = 4.55LKK2314 pKa = 11.16DD2315 pKa = 3.22LAYY2318 pKa = 10.51QQFLDD2323 pKa = 3.92ADD2325 pKa = 4.06TEE2327 pKa = 4.5IEE2329 pKa = 4.33VSADD2333 pKa = 3.32MPAGTVVAQIPYY2345 pKa = 8.88GWNHH2349 pKa = 6.58PFLNRR2354 pKa = 11.84YY2355 pKa = 7.56AKK2357 pKa = 10.19RR2358 pKa = 11.84WVQQHH2363 pKa = 4.96EE2364 pKa = 4.81RR2365 pKa = 11.84YY2366 pKa = 8.16TGSFKK2371 pKa = 10.8YY2372 pKa = 10.15RR2373 pKa = 11.84YY2374 pKa = 7.17TVIGNPLFSGAIGIAWVKK2392 pKa = 10.62KK2393 pKa = 10.26RR2394 pKa = 11.84ITTSIVPVSMMQKK2407 pKa = 9.54YY2408 pKa = 9.68SYY2410 pKa = 9.38SAKK2413 pKa = 9.94GVTMPWNVIHH2423 pKa = 6.53TLHH2426 pKa = 7.47DD2427 pKa = 3.23ARR2429 pKa = 11.84KK2430 pKa = 7.96QYY2432 pKa = 10.58FYY2434 pKa = 11.43RR2435 pKa = 11.84EE2436 pKa = 4.19VEE2438 pKa = 4.86DD2439 pKa = 6.44DD2440 pKa = 5.07LDD2442 pKa = 5.27DD2443 pKa = 6.32DD2444 pKa = 4.36NLADD2448 pKa = 4.51RR2449 pKa = 11.84PHH2451 pKa = 6.84LVLFLLMSLQNPLQPGVITRR2471 pKa = 11.84VRR2473 pKa = 11.84IASKK2477 pKa = 10.28LATVGEE2483 pKa = 4.55GNPFRR2488 pKa = 11.84ALDD2491 pKa = 3.97PADD2494 pKa = 3.84TDD2496 pKa = 3.98TAPEE2500 pKa = 4.26TTTTPVPQNRR2510 pKa = 11.84FQSVFPQDD2518 pKa = 3.29LNKK2521 pKa = 10.49RR2522 pKa = 11.84IWLYY2526 pKa = 11.07TDD2528 pKa = 3.72GQLSASTNPTMEE2540 pKa = 4.57AYY2542 pKa = 9.74YY2543 pKa = 10.35PDD2545 pKa = 4.25MIYY2548 pKa = 10.37EE2549 pKa = 3.98ARR2551 pKa = 11.84KK2552 pKa = 9.55NGIIGGQVGGTDD2564 pKa = 3.83PNDD2567 pKa = 2.95LSTYY2571 pKa = 10.3YY2572 pKa = 10.6NVEE2575 pKa = 3.0NWARR2579 pKa = 11.84TDD2581 pKa = 3.21TVTNLTADD2589 pKa = 4.06WPWMSGKK2596 pKa = 10.04SVSPGDD2602 pKa = 3.67YY2603 pKa = 7.57VTVYY2607 pKa = 8.95ITTVTNMDD2615 pKa = 3.34QKK2617 pKa = 11.51SFYY2620 pKa = 11.47AWINNNNWAGFQKK2633 pKa = 10.6QPGGNTMTWNKK2644 pKa = 8.71WNANKK2649 pKa = 10.51GYY2651 pKa = 10.62LPAPQLAGGVLTHH2664 pKa = 6.9SSTYY2668 pKa = 10.5NQTEE2672 pKa = 4.31LKK2674 pKa = 10.43FSTNASLGYY2683 pKa = 10.45GFSNTIKK2690 pKa = 10.29EE2691 pKa = 4.22WIKK2694 pKa = 10.7YY2695 pKa = 6.74VTDD2698 pKa = 3.17KK2699 pKa = 10.68GTIYY2703 pKa = 10.77FLLCYY2708 pKa = 8.57TEE2710 pKa = 3.98QMRR2713 pKa = 11.84GIAATPYY2720 pKa = 8.21PRR2722 pKa = 11.84QVASRR2727 pKa = 11.84FAGHH2731 pKa = 6.03YY2732 pKa = 7.07QTQTVQNLPQYY2743 pKa = 10.38PIFNVDD2749 pKa = 3.27EE2750 pKa = 4.09QLGSIRR2756 pKa = 11.84GNINTLPSGNLLFRR2770 pKa = 11.84MTEE2773 pKa = 3.93MPPSSVAVGQAQMPTCSDD2791 pKa = 3.02NATIAKK2797 pKa = 9.45YY2798 pKa = 9.6FALLSQGLATLQCLQFRR2815 pKa = 11.84LIDD2818 pKa = 3.97AQSVRR2823 pKa = 11.84QIATVRR2829 pKa = 11.84YY2830 pKa = 8.07LQEE2833 pKa = 3.82SQVFVINAPNSPTRR2847 pKa = 11.84YY2848 pKa = 9.11RR2849 pKa = 11.84VVPQNNEE2856 pKa = 3.86NIIIGQITVVQRR2868 pKa = 11.84ATDD2871 pKa = 3.71FQEE2874 pKa = 4.07TVTFDD2879 pKa = 2.76WTDD2882 pKa = 3.17RR2883 pKa = 11.84VAPEE2887 pKa = 3.52FLRR2890 pKa = 11.84RR2891 pKa = 11.84GDD2893 pKa = 3.64VFKK2896 pKa = 10.19TAISPDD2902 pKa = 3.65LFSDD2906 pKa = 3.69VTPQKK2911 pKa = 10.92DD2912 pKa = 3.75GYY2914 pKa = 8.0TANATLLASMAGGALGGIGQAIGQHH2939 pKa = 5.14QNRR2942 pKa = 11.84KK2943 pKa = 8.9HH2944 pKa = 5.35EE2945 pKa = 5.12KK2946 pKa = 9.95EE2947 pKa = 3.89MQSNQFGHH2955 pKa = 6.59EE2956 pKa = 3.86EE2957 pKa = 4.07TMQGNMFNFQNQFQQQGFDD2976 pKa = 3.71FQKK2979 pKa = 10.35MMQEE2983 pKa = 4.01NQFGFQNKK2991 pKa = 8.39YY2992 pKa = 7.99QAQQHH2997 pKa = 4.98YY2998 pKa = 10.11QEE3000 pKa = 4.49QLLQEE3005 pKa = 4.16RR3006 pKa = 11.84GYY3008 pKa = 11.3QNDD3011 pKa = 3.74LGLLQSSHH3019 pKa = 4.94QEE3021 pKa = 3.47QRR3023 pKa = 11.84ITNKK3027 pKa = 9.54EE3028 pKa = 3.73QSHH3031 pKa = 5.39NRR3033 pKa = 11.84MTEE3036 pKa = 3.61RR3037 pKa = 11.84GLSSRR3042 pKa = 11.84VMGMPGAVTSASSAA3056 pKa = 3.33

Molecular weight: 344.33 kDa
Isoelectric point according different methods:

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

For dipeptide frequency statistics click here

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here