Average proteome isoelectric point is 6.83

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

    

All

Note: above files contain also dissociation constants (pKa)

Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

    

>tr|A0A0G2UMQ9|A0A0G2UMQ9_9VIRU Replicase OS=Issyk-Kul virus OX=1453408 PE=4 SV=1
SS1 pKa = 7.3SDD3 pKa = 3.8LEE5 pKa = 4.43NIAWEE10 pKa = 4.1QVTQEE15 pKa = 4.39FSTAVCNFPIEE26 pKa = 4.26EE27 pKa = 4.31VFNIDD32 pKa = 4.03PMLPDD37 pKa = 3.77GRR39 pKa = 11.84CFFRR43 pKa = 11.84AMAKK47 pKa = 10.4FMFNSSDD54 pKa = 2.49EE55 pKa = 3.98WLIVKK60 pKa = 8.15RR61 pKa = 11.84ACIEE65 pKa = 3.76YY66 pKa = 10.41SRR68 pKa = 11.84QHH70 pKa = 5.27WNRR73 pKa = 11.84FLVYY77 pKa = 9.34TRR79 pKa = 11.84LYY81 pKa = 9.56PSSADD86 pKa = 3.47YY87 pKa = 11.03EE88 pKa = 4.26RR89 pKa = 11.84DD90 pKa = 3.47IMRR93 pKa = 11.84DD94 pKa = 3.83DD95 pKa = 3.38YY96 pKa = 11.44WGGSLEE102 pKa = 4.66AEE104 pKa = 4.42VLSDD108 pKa = 4.5LYY110 pKa = 11.6NLTIHH115 pKa = 6.66FWVTDD120 pKa = 3.3DD121 pKa = 4.29HH122 pKa = 7.2QWIHH126 pKa = 6.51HH127 pKa = 4.51VQRR130 pKa = 11.84WKK132 pKa = 11.3NNAPHH137 pKa = 6.23MSINLLFNQNHH148 pKa = 6.38FDD150 pKa = 3.95LLNLKK155 pKa = 9.77EE156 pKa = 4.15FEE158 pKa = 4.2EE159 pKa = 5.12DD160 pKa = 3.76EE161 pKa = 4.51EE162 pKa = 4.25NLPILPLEE170 pKa = 4.35EE171 pKa = 4.5KK172 pKa = 10.44VDD174 pKa = 3.31IAIRR178 pKa = 11.84SVVTDD183 pKa = 3.92SEE185 pKa = 4.77DD186 pKa = 3.44GSEE189 pKa = 3.93PSFLRR194 pKa = 11.84DD195 pKa = 3.11ISVEE199 pKa = 4.02DD200 pKa = 3.35STSTFKK206 pKa = 11.09RR207 pKa = 11.84NLDD210 pKa = 3.73LEE212 pKa = 4.48LMEE215 pKa = 4.32MANMKK220 pKa = 10.06EE221 pKa = 3.77LLLTKK226 pKa = 10.14KK227 pKa = 10.44GNKK230 pKa = 9.4RR231 pKa = 11.84GSKK234 pKa = 9.6QVADD238 pKa = 3.83MKK240 pKa = 11.14EE241 pKa = 3.6KK242 pKa = 10.8DD243 pKa = 3.3FRR245 pKa = 11.84KK246 pKa = 9.97AVEE249 pKa = 4.16KK250 pKa = 10.78GKK252 pKa = 10.38QIPLKK257 pKa = 10.45AGRR260 pKa = 11.84ILNHH264 pKa = 6.67LFSIQIEE271 pKa = 4.46GVNEE275 pKa = 4.03GEE277 pKa = 5.32LLILYY282 pKa = 8.65PKK284 pKa = 10.25DD285 pKa = 3.9FNHH288 pKa = 6.46KK289 pKa = 10.03RR290 pKa = 11.84PGAFSITDD298 pKa = 4.07LGHH301 pKa = 7.3KK302 pKa = 10.26LLDD305 pKa = 4.03GNKK308 pKa = 9.13EE309 pKa = 3.92FAKK312 pKa = 10.61SISKK316 pKa = 8.67LTLVISGEE324 pKa = 3.9LMTYY328 pKa = 10.62LNSSYY333 pKa = 10.39LIRR336 pKa = 11.84MCFPGTGLSQTPDD349 pKa = 3.66LLHH352 pKa = 6.59PAIKK356 pKa = 9.52IDD358 pKa = 3.69ATILACAVLISSFLYY373 pKa = 10.46KK374 pKa = 10.36SSNDD378 pKa = 3.07IKK380 pKa = 11.09RR381 pKa = 11.84KK382 pKa = 9.27FLTLACGRR390 pKa = 11.84MGINTSKK397 pKa = 10.76LFKK400 pKa = 10.89EE401 pKa = 4.26MLNFCNTEE409 pKa = 4.04MYY411 pKa = 9.97EE412 pKa = 4.07SLYY415 pKa = 10.98KK416 pKa = 10.43VVQHH420 pKa = 6.36LSGVFLRR427 pKa = 11.84KK428 pKa = 9.18QVEE431 pKa = 4.31EE432 pKa = 3.71VSEE435 pKa = 4.08FLKK438 pKa = 11.06RR439 pKa = 11.84MGPQSKK445 pKa = 9.94LALQCINLEE454 pKa = 4.17SCDD457 pKa = 3.45LKK459 pKa = 10.98QYY461 pKa = 11.12KK462 pKa = 9.98KK463 pKa = 10.67LLQEE467 pKa = 3.89LSEE470 pKa = 4.89RR471 pKa = 11.84DD472 pKa = 3.55MNDD475 pKa = 2.66VNFNSEE481 pKa = 4.39EE482 pKa = 3.97IKK484 pKa = 10.7DD485 pKa = 3.57LHH487 pKa = 6.3EE488 pKa = 4.99CIEE491 pKa = 4.89LISKK495 pKa = 10.04LSNASKK501 pKa = 10.48PNADD505 pKa = 3.01IKK507 pKa = 11.28SKK509 pKa = 9.68VRR511 pKa = 11.84QYY513 pKa = 9.28CTHH516 pKa = 5.84VPNKK520 pKa = 10.17KK521 pKa = 9.9KK522 pKa = 10.83LEE524 pKa = 4.26RR525 pKa = 11.84GNIKK529 pKa = 10.37DD530 pKa = 5.11LIGLCIIEE538 pKa = 4.1FFMRR542 pKa = 11.84KK543 pKa = 8.7MIFKK547 pKa = 10.11FVSLQGKK554 pKa = 9.03AYY556 pKa = 10.6SGASLGNLLAYY567 pKa = 9.96AHH569 pKa = 6.56NLYY572 pKa = 10.45LSKK575 pKa = 11.05DD576 pKa = 3.79SLNLTIEE583 pKa = 4.74DD584 pKa = 4.43LSQLDD589 pKa = 3.69VEE591 pKa = 4.49IRR593 pKa = 11.84RR594 pKa = 11.84LNTLMSVDD602 pKa = 3.44VKK604 pKa = 11.2KK605 pKa = 10.33PVALICMEE613 pKa = 4.54LEE615 pKa = 4.13RR616 pKa = 11.84KK617 pKa = 7.31FTRR620 pKa = 11.84LFEE623 pKa = 4.25QLPEE627 pKa = 4.28DD628 pKa = 4.36CKK630 pKa = 11.18HH631 pKa = 5.41EE632 pKa = 4.4CEE634 pKa = 4.77TLFTDD639 pKa = 3.42IRR641 pKa = 11.84NAEE644 pKa = 4.22SHH646 pKa = 5.73SSAWRR651 pKa = 11.84SALRR655 pKa = 11.84LKK657 pKa = 9.17GTAYY661 pKa = 9.93EE662 pKa = 4.33GLFSKK667 pKa = 10.35HH668 pKa = 5.75YY669 pKa = 8.23NWSYY673 pKa = 10.33TPEE676 pKa = 4.22DD677 pKa = 4.04LKK679 pKa = 11.18PSLGMSIQTLFPEE692 pKa = 4.27KK693 pKa = 10.67FEE695 pKa = 4.25MFLEE699 pKa = 4.62RR700 pKa = 11.84THH702 pKa = 6.44LHH704 pKa = 6.09PEE706 pKa = 3.93FRR708 pKa = 11.84DD709 pKa = 3.55LVPDD713 pKa = 4.14FFLYY717 pKa = 9.82KK718 pKa = 10.19PRR720 pKa = 11.84IIKK723 pKa = 10.24EE724 pKa = 4.08DD725 pKa = 3.43TFEE728 pKa = 5.0ASITRR733 pKa = 11.84KK734 pKa = 10.33DD735 pKa = 3.66DD736 pKa = 3.81DD737 pKa = 3.81QEE739 pKa = 4.17KK740 pKa = 10.51HH741 pKa = 5.58VDD743 pKa = 3.58HH744 pKa = 7.1IEE746 pKa = 4.04AVEE749 pKa = 4.1DD750 pKa = 3.66ASTVKK755 pKa = 9.63LTSKK759 pKa = 10.37KK760 pKa = 10.08RR761 pKa = 11.84FPLPEE766 pKa = 3.84VNIQEE771 pKa = 4.34VLSTHH776 pKa = 5.76NLYY779 pKa = 10.75KK780 pKa = 10.81GFEE783 pKa = 3.99TRR785 pKa = 11.84GRR787 pKa = 11.84EE788 pKa = 3.85KK789 pKa = 10.74NRR791 pKa = 11.84PILTKK796 pKa = 10.0STEE799 pKa = 3.87QDD801 pKa = 2.76ASNDD805 pKa = 3.37EE806 pKa = 4.14EE807 pKa = 4.83VKK809 pKa = 11.12VNEE812 pKa = 4.26LCLMAVEE819 pKa = 4.91VGYY822 pKa = 8.09QTDD825 pKa = 3.61VEE827 pKa = 4.64GKK829 pKa = 10.28VISDD833 pKa = 3.36MKK835 pKa = 10.75KK836 pKa = 7.25WDD838 pKa = 3.44SVIRR842 pKa = 11.84LMKK845 pKa = 10.35HH846 pKa = 4.94IGVNFSVVACADD858 pKa = 3.42STNTPKK864 pKa = 10.59SDD866 pKa = 2.39WWIPEE871 pKa = 4.15DD872 pKa = 4.38MVQLLLNSISHH883 pKa = 6.92LFKK886 pKa = 10.6EE887 pKa = 4.48LQEE890 pKa = 4.13NSPVDD895 pKa = 3.62VTDD898 pKa = 3.37IAVGNISTQKK908 pKa = 9.23VRR910 pKa = 11.84SVLRR914 pKa = 11.84SGAIVKK920 pKa = 8.81TPVTFKK926 pKa = 10.75EE927 pKa = 4.21ITEE930 pKa = 4.14TWHH933 pKa = 5.47VLKK936 pKa = 10.56EE937 pKa = 4.11HH938 pKa = 7.22IINRR942 pKa = 11.84PTGAVLDD949 pKa = 4.22KK950 pKa = 10.14FTEE953 pKa = 4.11NAMEE957 pKa = 4.43ASLVEE962 pKa = 4.21GAILTRR968 pKa = 11.84EE969 pKa = 3.97SAEE972 pKa = 4.77DD973 pKa = 3.3ILEE976 pKa = 4.35HH977 pKa = 7.41VLEE980 pKa = 4.72NMDD983 pKa = 4.37KK984 pKa = 10.64IIGEE988 pKa = 4.07MQKK991 pKa = 9.1TKK993 pKa = 10.45FKK995 pKa = 11.26HH996 pKa = 6.06EE997 pKa = 3.48ISKK1000 pKa = 9.44NQRR1003 pKa = 11.84SAFKK1007 pKa = 10.96LLIGWMNEE1015 pKa = 3.98DD1016 pKa = 3.16ILSYY1020 pKa = 10.66RR1021 pKa = 11.84CNDD1024 pKa = 3.53CLKK1027 pKa = 10.46SIQSNISKK1035 pKa = 10.07IEE1037 pKa = 3.87TEE1039 pKa = 4.42AEE1041 pKa = 4.12VASYY1045 pKa = 10.04LARR1048 pKa = 11.84EE1049 pKa = 4.27LMPVEE1054 pKa = 4.4KK1055 pKa = 10.0DD1056 pKa = 3.31CCKK1059 pKa = 10.82SMPHH1063 pKa = 6.02TYY1065 pKa = 9.68EE1066 pKa = 3.66VSSVQRR1072 pKa = 11.84RR1073 pKa = 11.84IPSLTNIKK1081 pKa = 10.1HH1082 pKa = 5.9KK1083 pKa = 10.33PLVVNEE1089 pKa = 4.2NKK1091 pKa = 9.48TEE1093 pKa = 4.13KK1094 pKa = 10.58DD1095 pKa = 3.33GSSTVLDD1102 pKa = 3.71SLVTLTLPGKK1112 pKa = 7.34TEE1114 pKa = 3.83KK1115 pKa = 10.12EE1116 pKa = 4.09RR1117 pKa = 11.84KK1118 pKa = 8.59IKK1120 pKa = 10.53RR1121 pKa = 11.84AVEE1124 pKa = 3.66QLIRR1128 pKa = 11.84AIMRR1132 pKa = 11.84HH1133 pKa = 5.32SSLPAIKK1140 pKa = 10.26LPSGHH1145 pKa = 7.4LLLDD1149 pKa = 3.91HH1150 pKa = 6.55NLNRR1154 pKa = 11.84PIYY1157 pKa = 10.22DD1158 pKa = 3.59EE1159 pKa = 4.22EE1160 pKa = 4.93NEE1162 pKa = 4.14GKK1164 pKa = 10.13SFKK1167 pKa = 10.63KK1168 pKa = 10.47GGLKK1172 pKa = 10.18SRR1174 pKa = 11.84EE1175 pKa = 3.36EE1176 pKa = 4.0DD1177 pKa = 3.19MEE1179 pKa = 4.4HH1180 pKa = 6.48FKK1182 pKa = 11.24KK1183 pKa = 10.76LLSEE1187 pKa = 4.66SKK1189 pKa = 9.75LSSYY1193 pKa = 10.87SEE1195 pKa = 4.16HH1196 pKa = 6.08TKK1198 pKa = 10.65HH1199 pKa = 6.92VILAAINNLSNCKK1212 pKa = 9.48GAKK1215 pKa = 9.77CSVSQMWVKK1224 pKa = 10.95NILYY1228 pKa = 9.66DD1229 pKa = 4.28LKK1231 pKa = 11.06SDD1233 pKa = 3.64TSDD1236 pKa = 3.05EE1237 pKa = 4.41VIMQKK1242 pKa = 8.78VQEE1245 pKa = 4.38SYY1247 pKa = 10.76EE1248 pKa = 4.11KK1249 pKa = 10.56KK1250 pKa = 10.23QNFSNEE1256 pKa = 3.72RR1257 pKa = 11.84KK1258 pKa = 9.34FKK1260 pKa = 10.14YY1261 pKa = 10.1RR1262 pKa = 11.84PIGWSQIKK1270 pKa = 10.36DD1271 pKa = 3.4YY1272 pKa = 11.14LLSKK1276 pKa = 10.54KK1277 pKa = 9.07EE1278 pKa = 4.41LYY1280 pKa = 10.97GSMSVPVFSLDD1291 pKa = 3.58CILFKK1296 pKa = 10.34EE1297 pKa = 4.69VCHH1300 pKa = 5.57EE1301 pKa = 4.0VLRR1304 pKa = 11.84RR1305 pKa = 11.84LANTPYY1311 pKa = 10.12QPCIDD1316 pKa = 4.54YY1317 pKa = 10.58IVEE1320 pKa = 4.06LLKK1323 pKa = 11.22LLLKK1327 pKa = 8.75FQWYY1331 pKa = 9.36QEE1333 pKa = 3.74LVYY1336 pKa = 10.55YY1337 pKa = 10.72SKK1339 pKa = 11.17VCEE1342 pKa = 4.27TFLQSCSEE1350 pKa = 3.95FHH1352 pKa = 7.1RR1353 pKa = 11.84SGIKK1357 pKa = 9.48VLRR1360 pKa = 11.84IRR1362 pKa = 11.84HH1363 pKa = 5.75TDD1365 pKa = 3.17TNLVIALPANKK1376 pKa = 8.84KK1377 pKa = 10.02QNMRR1381 pKa = 11.84CCIYY1385 pKa = 10.96SKK1387 pKa = 10.75DD1388 pKa = 3.47FSLIKK1393 pKa = 10.62GPFMLNRR1400 pKa = 11.84RR1401 pKa = 11.84QAVLGAAYY1409 pKa = 9.99CYY1411 pKa = 10.12IIPICFLQCLQHH1423 pKa = 5.44YY1424 pKa = 9.04RR1425 pKa = 11.84CVSEE1429 pKa = 6.63LEE1431 pKa = 4.24TLDD1434 pKa = 3.52QNIMKK1439 pKa = 10.38DD1440 pKa = 2.8ILRR1443 pKa = 11.84RR1444 pKa = 11.84SEE1446 pKa = 3.9QLHH1449 pKa = 5.89NLLLEE1454 pKa = 4.41TLEE1457 pKa = 3.92MTYY1460 pKa = 11.11NGVFEE1465 pKa = 4.33TAKK1468 pKa = 8.21TTLLNFCKK1476 pKa = 10.47KK1477 pKa = 10.11SGNFMTRR1484 pKa = 11.84GTRR1487 pKa = 11.84DD1488 pKa = 3.07QFICCFSGLSVTFSTLLGDD1507 pKa = 3.92SLLNNSQPFNKK1518 pKa = 9.08QIQMMRR1524 pKa = 11.84FGLLSAISRR1533 pKa = 11.84LNCPKK1538 pKa = 10.52EE1539 pKa = 3.83LGKK1542 pKa = 10.69KK1543 pKa = 10.34FSSSCRR1549 pKa = 11.84KK1550 pKa = 10.0VEE1552 pKa = 3.83FHH1554 pKa = 6.69VSKK1557 pKa = 10.87LYY1559 pKa = 8.73MQLVVFSANYY1569 pKa = 9.61NVEE1572 pKa = 4.47TNCEE1576 pKa = 3.7NWLKK1580 pKa = 10.19TDD1582 pKa = 3.92LCSQAEE1588 pKa = 4.46LPCFSIFGMFINSDD1602 pKa = 3.28RR1603 pKa = 11.84QLIFDD1608 pKa = 4.36IYY1610 pKa = 10.74LVHH1613 pKa = 7.26IYY1615 pKa = 10.18NKK1617 pKa = 10.41EE1618 pKa = 3.62MDD1620 pKa = 5.31DD1621 pKa = 4.28FDD1623 pKa = 4.15EE1624 pKa = 5.14GCIKK1628 pKa = 10.61VLEE1631 pKa = 4.42EE1632 pKa = 3.51TAEE1635 pKa = 3.9RR1636 pKa = 11.84HH1637 pKa = 5.3AAWEE1641 pKa = 3.94ISLKK1645 pKa = 10.79RR1646 pKa = 11.84NLEE1649 pKa = 4.13LSQKK1653 pKa = 9.31RR1654 pKa = 11.84HH1655 pKa = 5.36QKK1657 pKa = 10.52DD1658 pKa = 3.22KK1659 pKa = 11.21PKK1661 pKa = 11.08DD1662 pKa = 3.44KK1663 pKa = 11.26VLFQDD1668 pKa = 5.32DD1669 pKa = 3.93SAKK1672 pKa = 9.93EE1673 pKa = 3.67AKK1675 pKa = 9.51LAQRR1679 pKa = 11.84RR1680 pKa = 11.84VRR1682 pKa = 11.84LLLGLPNIKK1691 pKa = 10.03KK1692 pKa = 9.6MSEE1695 pKa = 4.19SYY1697 pKa = 10.78VDD1699 pKa = 3.42SRR1701 pKa = 11.84DD1702 pKa = 3.58VEE1704 pKa = 4.32EE1705 pKa = 5.44EE1706 pKa = 3.98EE1707 pKa = 5.22DD1708 pKa = 3.76LSSSSKK1714 pKa = 9.72TSSTMSYY1721 pKa = 9.34TSRR1724 pKa = 11.84NSKK1727 pKa = 10.6SSIKK1731 pKa = 9.89SARR1734 pKa = 11.84SFAKK1738 pKa = 9.9RR1739 pKa = 11.84RR1740 pKa = 11.84NPPTSMFGIRR1750 pKa = 11.84ASKK1753 pKa = 9.0QKK1755 pKa = 10.35PMSIEE1760 pKa = 3.83SGFVITRR1767 pKa = 11.84DD1768 pKa = 3.59DD1769 pKa = 3.71KK1770 pKa = 11.42RR1771 pKa = 11.84DD1772 pKa = 3.56YY1773 pKa = 10.58QQAITDD1779 pKa = 3.24KK1780 pKa = 10.88GLYY1783 pKa = 9.41HH1784 pKa = 7.51EE1785 pKa = 4.51YY1786 pKa = 10.16RR1787 pKa = 11.84ANKK1790 pKa = 9.74EE1791 pKa = 4.4SVFKK1795 pKa = 10.7DD1796 pKa = 2.9IIIIIRR1802 pKa = 11.84EE1803 pKa = 4.22NPNHH1807 pKa = 6.05TFGSFEE1813 pKa = 5.28LIQACTEE1820 pKa = 3.55IARR1823 pKa = 11.84AKK1825 pKa = 10.09FPPEE1829 pKa = 4.95AIDD1832 pKa = 3.41KK1833 pKa = 10.73AKK1835 pKa = 10.24RR1836 pKa = 11.84DD1837 pKa = 3.6PRR1839 pKa = 11.84NWISVSEE1846 pKa = 4.25VTEE1849 pKa = 4.17TTSIIAEE1856 pKa = 3.89PRR1858 pKa = 11.84DD1859 pKa = 3.79FIFIKK1864 pKa = 10.28DD1865 pKa = 3.59AYY1867 pKa = 10.3RR1868 pKa = 11.84IIIGNEE1874 pKa = 3.49NKK1876 pKa = 10.45KK1877 pKa = 9.03MVKK1880 pKa = 10.0LLRR1883 pKa = 11.84GKK1885 pKa = 8.16FQRR1888 pKa = 11.84LGMSCKK1894 pKa = 10.2SEE1896 pKa = 3.74GHH1898 pKa = 6.72DD1899 pKa = 3.49RR1900 pKa = 11.84VHH1902 pKa = 6.07CQEE1905 pKa = 4.77LLSTIPSLTDD1915 pKa = 3.18KK1916 pKa = 11.2QKK1918 pKa = 11.58DD1919 pKa = 3.8DD1920 pKa = 4.15IIKK1923 pKa = 10.84GIINPSKK1930 pKa = 9.36LTFYY1934 pKa = 10.81NWQEE1938 pKa = 4.07LIKK1941 pKa = 10.81KK1942 pKa = 8.83GVNEE1946 pKa = 4.04VLLTNDD1952 pKa = 3.43GNYY1955 pKa = 9.16IFCWLKK1961 pKa = 10.9SLSQMVKK1968 pKa = 9.37SGLRR1972 pKa = 11.84GEE1974 pKa = 4.44IKK1976 pKa = 10.13NLKK1979 pKa = 8.56YY1980 pKa = 11.0GPMLQKK1986 pKa = 10.93GKK1988 pKa = 10.1LCPKK1992 pKa = 10.38SKK1994 pKa = 10.05ILSSEE1999 pKa = 3.74EE2000 pKa = 3.24HH2001 pKa = 5.89SAIKK2005 pKa = 10.46RR2006 pKa = 11.84FIEE2009 pKa = 4.16FLKK2012 pKa = 10.6SCTKK2016 pKa = 11.05GEE2018 pKa = 4.09VTEE2021 pKa = 5.62DD2022 pKa = 3.18INKK2025 pKa = 10.04SDD2027 pKa = 4.18ISITDD2032 pKa = 5.39LILAWVKK2039 pKa = 8.09FTKK2042 pKa = 10.09SSKK2045 pKa = 9.83LSKK2048 pKa = 9.85TIILDD2053 pKa = 3.7GLHH2056 pKa = 6.42SLRR2059 pKa = 11.84NLSEE2063 pKa = 4.1KK2064 pKa = 10.49LKK2066 pKa = 11.13KK2067 pKa = 10.13LDD2069 pKa = 3.22QDD2071 pKa = 4.09YY2072 pKa = 8.33NTLITLKK2079 pKa = 10.48KK2080 pKa = 8.74EE2081 pKa = 3.77LPGISFSKK2089 pKa = 10.91EE2090 pKa = 3.68EE2091 pKa = 3.62ILLRR2095 pKa = 11.84QGEE2098 pKa = 4.42KK2099 pKa = 9.81MLLLAHH2105 pKa = 7.17DD2106 pKa = 4.69KK2107 pKa = 11.09DD2108 pKa = 4.16IMHH2111 pKa = 7.0LTNLLFLICLSCPWCIQYY2129 pKa = 8.26KK2130 pKa = 7.49TFEE2133 pKa = 5.69AIMMRR2138 pKa = 11.84NMAEE2142 pKa = 3.86AEE2144 pKa = 4.25GFNLPKK2150 pKa = 10.5SGTTINEE2157 pKa = 3.89LHH2159 pKa = 7.3PDD2161 pKa = 3.4SVINILMEE2169 pKa = 4.2EE2170 pKa = 3.88VDD2172 pKa = 5.04FFLDD2176 pKa = 3.61EE2177 pKa = 4.17QTVTLCTKK2185 pKa = 10.52YY2186 pKa = 10.78CMCLFSINEE2195 pKa = 4.03LPYY2198 pKa = 11.16ASALNSNEE2206 pKa = 3.25ALTYY2210 pKa = 10.2HH2211 pKa = 6.42SPNDD2215 pKa = 3.44QLMSRR2220 pKa = 11.84VKK2222 pKa = 10.45HH2223 pKa = 5.57IMAVTGLRR2231 pKa = 11.84DD2232 pKa = 3.33SRR2234 pKa = 11.84SDD2236 pKa = 3.69FKK2238 pKa = 10.43WTINLLANSNFEE2250 pKa = 4.12VTKK2253 pKa = 10.45KK2254 pKa = 8.73ITGRR2258 pKa = 11.84SVGEE2262 pKa = 3.71KK2263 pKa = 9.87LPRR2266 pKa = 11.84SVRR2269 pKa = 11.84SKK2271 pKa = 10.82VIYY2274 pKa = 10.06EE2275 pKa = 4.08VVKK2278 pKa = 10.93LVDD2281 pKa = 3.64NTEE2284 pKa = 4.0MAILQQLSFTYY2295 pKa = 10.53ILDD2298 pKa = 3.57TNHH2301 pKa = 6.95RR2302 pKa = 11.84FFAVLAPKK2310 pKa = 10.11AQLGGHH2316 pKa = 6.75RR2317 pKa = 11.84DD2318 pKa = 3.56LLVQEE2323 pKa = 5.11TGTKK2327 pKa = 9.09MIHH2330 pKa = 6.09ATTEE2334 pKa = 3.96MFSRR2338 pKa = 11.84TLLSTTKK2345 pKa = 10.82DD2346 pKa = 3.3DD2347 pKa = 3.92GLTNSGLKK2355 pKa = 10.24EE2356 pKa = 4.32SILNAGLEE2364 pKa = 4.77AINTMKK2370 pKa = 10.65LNHH2373 pKa = 6.54GKK2375 pKa = 8.02EE2376 pKa = 4.43TYY2378 pKa = 8.81PQSGQFQFYY2387 pKa = 9.72KK2388 pKa = 10.14VCCISGDD2395 pKa = 3.54NTKK2398 pKa = 9.68WGPIHH2403 pKa = 6.75CCSLFSGMMQQLLKK2417 pKa = 10.77DD2418 pKa = 3.54INDD2421 pKa = 3.55WSCYY2425 pKa = 9.66YY2426 pKa = 11.14KK2427 pKa = 10.29LTFLKK2432 pKa = 10.39NLCRR2436 pKa = 11.84QVEE2439 pKa = 4.39IPSSSIRR2446 pKa = 11.84KK2447 pKa = 8.63ILNSFKK2453 pKa = 11.03YY2454 pKa = 10.04KK2455 pKa = 10.73NSDD2458 pKa = 3.45VKK2460 pKa = 11.1VDD2462 pKa = 4.01EE2463 pKa = 4.8LPEE2466 pKa = 5.84DD2467 pKa = 4.1EE2468 pKa = 4.9LRR2470 pKa = 11.84DD2471 pKa = 3.68MLFQRR2476 pKa = 11.84IDD2478 pKa = 2.96TWNDD2482 pKa = 2.61NEE2484 pKa = 4.44IIKK2487 pKa = 10.24FLVANYY2493 pKa = 9.54ISKK2496 pKa = 11.02GKK2498 pKa = 8.75MAINSYY2504 pKa = 9.12NHH2506 pKa = 6.1MGQGIHH2512 pKa = 6.61HH2513 pKa = 6.8ATSSVLTSIMAHH2525 pKa = 6.71IIEE2528 pKa = 4.46TLIKK2532 pKa = 10.16RR2533 pKa = 11.84YY2534 pKa = 8.98FKK2536 pKa = 11.06KK2537 pKa = 10.13HH2538 pKa = 5.31MPDD2541 pKa = 3.45LEE2543 pKa = 4.36VSVTSAGSSDD2553 pKa = 5.4DD2554 pKa = 3.62YY2555 pKa = 11.44AKK2557 pKa = 10.78CIVAFGVLNRR2567 pKa = 11.84ALYY2570 pKa = 9.52NHH2572 pKa = 6.19YY2573 pKa = 10.37EE2574 pKa = 3.96EE2575 pKa = 5.7SFWEE2579 pKa = 4.36HH2580 pKa = 4.72MCRR2583 pKa = 11.84LKK2585 pKa = 11.19NLISGFSRR2593 pKa = 11.84ACQMKK2598 pKa = 10.46DD2599 pKa = 2.86SAKK2602 pKa = 9.96TLVSDD2607 pKa = 4.79CFFEE2611 pKa = 5.03FYY2613 pKa = 10.81SEE2615 pKa = 4.3FMMSQRR2621 pKa = 11.84ITPAVIKK2628 pKa = 10.02FILTGLINSSVTSPLSLIQACHH2650 pKa = 5.87VSSQQAMYY2658 pKa = 10.97NSVPLVTNLAFTLFRR2673 pKa = 11.84QQMFYY2678 pKa = 11.06NHH2680 pKa = 6.47TEE2682 pKa = 3.87NFIRR2686 pKa = 11.84TYY2688 pKa = 11.04GHH2690 pKa = 6.61LTLGSVSSFGRR2701 pKa = 11.84LYY2703 pKa = 10.81VPKK2706 pKa = 9.97FSNLIGSSVALEE2718 pKa = 4.12DD2719 pKa = 4.17AEE2721 pKa = 5.01EE2722 pKa = 3.99ITKK2725 pKa = 10.35AANNLVKK2732 pKa = 10.77ASVHH2736 pKa = 5.11FPEE2739 pKa = 6.17AIGDD2743 pKa = 3.81SSPSNKK2749 pKa = 9.92ASDD2752 pKa = 4.46DD2753 pKa = 3.43SDD2755 pKa = 4.11SIYY2758 pKa = 11.2NATTDD2763 pKa = 3.5SGTEE2767 pKa = 3.98DD2768 pKa = 3.28TSSIGSGPSEE2778 pKa = 3.87SSAASFHH2785 pKa = 6.51FSLKK2789 pKa = 10.28RR2790 pKa = 11.84GLNSTEE2796 pKa = 3.71EE2797 pKa = 4.26DD2798 pKa = 3.82YY2799 pKa = 11.39LRR2801 pKa = 11.84CLDD2804 pKa = 3.42QCLSKK2809 pKa = 10.8EE2810 pKa = 4.1YY2811 pKa = 10.5LDD2813 pKa = 4.36NIYY2816 pKa = 10.76RR2817 pKa = 11.84HH2818 pKa = 6.45LNMLYY2823 pKa = 10.34LDD2825 pKa = 4.33NGDD2828 pKa = 3.97FSEE2831 pKa = 4.43DD2832 pKa = 3.36CYY2834 pKa = 11.16YY2835 pKa = 11.39SKK2837 pKa = 10.56ILEE2840 pKa = 4.43SYY2842 pKa = 9.25SVKK2845 pKa = 10.93NNDD2848 pKa = 3.29YY2849 pKa = 11.12LGDD2852 pKa = 3.94DD2853 pKa = 3.68EE2854 pKa = 6.0RR2855 pKa = 11.84SPEE2858 pKa = 4.17LVLMLLRR2865 pKa = 11.84SLLIVLISGYY2875 pKa = 10.32YY2876 pKa = 8.23RR2877 pKa = 11.84TFASEE2882 pKa = 4.15GTEE2885 pKa = 3.89KK2886 pKa = 10.67SVKK2889 pKa = 10.34ASLNRR2894 pKa = 11.84DD2895 pKa = 3.27EE2896 pKa = 5.14NRR2898 pKa = 11.84IIEE2901 pKa = 4.43DD2902 pKa = 3.68PMIQLLPEE2910 pKa = 3.9KK2911 pKa = 10.22LRR2913 pKa = 11.84RR2914 pKa = 11.84EE2915 pKa = 4.11LARR2918 pKa = 11.84LGLAKK2923 pKa = 9.92MEE2925 pKa = 4.31ASEE2928 pKa = 5.98LIQQPGPSDD2937 pKa = 3.55SLSSLVAHH2945 pKa = 7.26KK2946 pKa = 10.42LITMNCATEE2955 pKa = 4.34EE2956 pKa = 4.14YY2957 pKa = 9.2KK2958 pKa = 11.13AEE2960 pKa = 3.98VMRR2963 pKa = 11.84LKK2965 pKa = 9.56QTLTSRR2971 pKa = 11.84NVLHH2975 pKa = 6.63GLAGGIKK2982 pKa = 9.45EE2983 pKa = 4.48LSLPIYY2989 pKa = 9.23TIFMKK2994 pKa = 10.41SYY2996 pKa = 9.28FFKK2999 pKa = 10.42DD3000 pKa = 3.46TVFLEE3005 pKa = 5.46HH3006 pKa = 6.79YY3007 pKa = 10.15DD3008 pKa = 3.22RR3009 pKa = 11.84WNTKK3013 pKa = 9.25HH3014 pKa = 5.51SQNYY3018 pKa = 8.81RR3019 pKa = 11.84DD3020 pKa = 3.84SSGQQLTGKK3029 pKa = 9.79VVVKK3033 pKa = 8.2FTTWLDD3039 pKa = 3.33KK3040 pKa = 10.84FLSSTFTFDD3049 pKa = 3.09NTQCALFDD3057 pKa = 3.98SLFDD3061 pKa = 3.76EE3062 pKa = 4.29NLRR3065 pKa = 11.84FVEE3068 pKa = 4.31VVRR3071 pKa = 11.84YY3072 pKa = 8.72EE3073 pKa = 3.93GGMVNLCYY3081 pKa = 9.75QVSEE3085 pKa = 4.37LEE3087 pKa = 4.09ILEE3090 pKa = 4.63SEE3092 pKa = 4.46MKK3094 pKa = 10.24SLAMQFSEE3102 pKa = 5.36VNRR3105 pKa = 11.84QKK3107 pKa = 10.74IKK3109 pKa = 10.94VMEE3112 pKa = 4.51SGCADD3117 pKa = 4.15NILEE3121 pKa = 4.03AHH3123 pKa = 6.77KK3124 pKa = 10.94AVITKK3129 pKa = 10.34SKK3131 pKa = 10.18LYY3133 pKa = 10.2SASDD3137 pKa = 3.6SVRR3140 pKa = 11.84LTNNAAIVVGNLLDD3154 pKa = 3.99EE3155 pKa = 4.8GALMSAKK3162 pKa = 9.78PSKK3165 pKa = 10.28IDD3167 pKa = 3.37MGSLGRR3173 pKa = 11.84DD3174 pKa = 2.97RR3175 pKa = 11.84FKK3177 pKa = 11.24LSQFYY3182 pKa = 10.87SSLVEE3187 pKa = 4.37LVNEE3191 pKa = 4.08INNLSEE3197 pKa = 3.97ALKK3200 pKa = 10.43KK3201 pKa = 9.98EE3202 pKa = 3.59KK3203 pKa = 10.37RR3204 pKa = 11.84IINLEE3209 pKa = 4.17VVNKK3213 pKa = 9.3FANNLTLLCRR3223 pKa = 11.84LVQQARR3229 pKa = 11.84SKK3231 pKa = 9.18VTSFYY3236 pKa = 9.72MLKK3239 pKa = 10.75GSTTTNEE3246 pKa = 3.88PTVTEE3251 pKa = 4.25LVSFGIIEE3259 pKa = 4.16GKK3261 pKa = 10.41YY3262 pKa = 10.02FEE3264 pKa = 5.33LKK3266 pKa = 11.11DD3267 pKa = 3.51MDD3269 pKa = 5.44ADD3271 pKa = 4.01TSAYY3275 pKa = 9.32SLKK3278 pKa = 9.84YY3279 pKa = 9.72WKK3281 pKa = 10.31VLQCISAISVLPISDD3296 pKa = 3.94SNKK3299 pKa = 9.27TNLLNSFLNWKK3310 pKa = 9.77PSISEE3315 pKa = 4.05LYY3317 pKa = 9.61EE3318 pKa = 3.88RR3319 pKa = 11.84CPLSKK3324 pKa = 10.28KK3325 pKa = 8.24EE3326 pKa = 3.91KK3327 pKa = 9.96RR3328 pKa = 11.84VLEE3331 pKa = 4.12EE3332 pKa = 4.22FNGKK3336 pKa = 7.4TLLDD3340 pKa = 4.04LLASEE3345 pKa = 5.14LPSIKK3350 pKa = 10.01DD3351 pKa = 3.21DD3352 pKa = 3.54KK3353 pKa = 11.13QRR3355 pKa = 11.84NNLEE3359 pKa = 4.69DD3360 pKa = 3.04IVDD3363 pKa = 4.63FVRR3366 pKa = 11.84SPLTLLRR3373 pKa = 11.84KK3374 pKa = 9.6KK3375 pKa = 10.36PYY3377 pKa = 10.03IGVTANFQTWGDD3389 pKa = 3.79GQKK3392 pKa = 10.65DD3393 pKa = 3.56GRR3395 pKa = 11.84FTYY3398 pKa = 10.41SSSSGEE3404 pKa = 3.64ATGIFISTKK3413 pKa = 8.13LHH3415 pKa = 6.62LYY3417 pKa = 9.99LSHH3420 pKa = 7.08GSQALLLEE3428 pKa = 4.38VEE3430 pKa = 4.67KK3431 pKa = 11.0KK3432 pKa = 10.05VLAWLNKK3439 pKa = 9.07RR3440 pKa = 11.84RR3441 pKa = 11.84TDD3443 pKa = 3.31VVTQEE3448 pKa = 3.44QHH3450 pKa = 6.24YY3451 pKa = 10.27YY3452 pKa = 10.66FIDD3455 pKa = 3.91LLCDD3459 pKa = 3.91FRR3461 pKa = 11.84HH3462 pKa = 5.64VPKK3465 pKa = 10.35KK3466 pKa = 11.05ANDD3469 pKa = 3.82GTIKK3473 pKa = 10.37GVKK3476 pKa = 9.24PSRR3479 pKa = 11.84TEE3481 pKa = 3.52PKK3483 pKa = 9.9YY3484 pKa = 11.24LEE3486 pKa = 4.71FYY3488 pKa = 10.47DD3489 pKa = 4.26PKK3491 pKa = 11.43GEE3493 pKa = 4.12DD3494 pKa = 3.01KK3495 pKa = 10.95VVKK3498 pKa = 10.2IKK3500 pKa = 11.06ASILTVRR3507 pKa = 11.84KK3508 pKa = 10.04CGIKK3512 pKa = 10.32DD3513 pKa = 3.15ILSEE3517 pKa = 3.99PRR3519 pKa = 11.84LVWSMNSLTIIYY3531 pKa = 9.78DD3532 pKa = 3.66EE3533 pKa = 4.8QISKK3537 pKa = 11.14ASFHH3541 pKa = 7.38DD3542 pKa = 4.31NILEE3546 pKa = 3.87IRR3548 pKa = 11.84TLLDD3552 pKa = 2.81QALEE3556 pKa = 4.38VKK3558 pKa = 10.26EE3559 pKa = 4.13KK3560 pKa = 9.63TVPEE3564 pKa = 3.85AVYY3567 pKa = 10.03TDD3569 pKa = 3.6SKK3571 pKa = 10.2VTLSRR3576 pKa = 11.84TKK3578 pKa = 10.43FSSDD3582 pKa = 3.02LFLNSLLLLHH3592 pKa = 6.92HH3593 pKa = 6.7FLEE3596 pKa = 5.01HH3597 pKa = 6.26TPSSAIWEE3605 pKa = 4.45SQTKK3609 pKa = 10.27SEE3611 pKa = 4.82IIRR3614 pKa = 11.84YY3615 pKa = 9.23LDD3617 pKa = 3.57NKK3619 pKa = 10.94DD3620 pKa = 3.39GGKK3623 pKa = 11.06GNLKK3627 pKa = 10.6SIADD3631 pKa = 4.02NLAKK3635 pKa = 10.04STVNMITKK3643 pKa = 10.4DD3644 pKa = 3.12IVLEE3648 pKa = 4.13GAEE3651 pKa = 4.35EE3652 pKa = 3.91EE3653 pKa = 5.02KK3654 pKa = 10.38ICQVLTTALEE3664 pKa = 4.41KK3665 pKa = 11.17GDD3667 pKa = 3.82LTMNAWPEE3675 pKa = 3.95VQTYY3679 pKa = 10.8LDD3681 pKa = 3.98EE3682 pKa = 6.81NGMQNITLEE3691 pKa = 4.19FLQKK3695 pKa = 10.66GLSDD3699 pKa = 3.6SYY3701 pKa = 11.56SWQFKK3706 pKa = 8.44NTLIKK3711 pKa = 10.59SGPARR3716 pKa = 11.84LGGFRR3721 pKa = 11.84GLVSAVGAEE3730 pKa = 4.2SIPRR3734 pKa = 11.84FLAPLIADD3742 pKa = 4.25GKK3744 pKa = 10.56LLSKK3748 pKa = 10.74SLACFIQARR3757 pKa = 11.84NYY3759 pKa = 10.08LSKK3762 pKa = 11.02SGLTDD3767 pKa = 3.9LEE3769 pKa = 4.7LDD3771 pKa = 4.67GIVCTIIYY3779 pKa = 9.1CVQARR3784 pKa = 11.84QKK3786 pKa = 9.98IRR3788 pKa = 11.84KK3789 pKa = 7.6EE3790 pKa = 3.98HH3791 pKa = 5.72TFSPSTLLKK3800 pKa = 9.94MSSTRR3805 pKa = 11.84AFKK3808 pKa = 10.81SATDD3812 pKa = 3.28KK3813 pKa = 11.37YY3814 pKa = 10.44SINFEE3819 pKa = 4.28VVDD3822 pKa = 4.21EE3823 pKa = 4.27KK3824 pKa = 11.87VMVICKK3830 pKa = 10.15VNTVKK3835 pKa = 10.29IEE3837 pKa = 4.05EE3838 pKa = 4.01IRR3840 pKa = 11.84RR3841 pKa = 11.84SRR3843 pKa = 11.84KK3844 pKa = 8.82EE3845 pKa = 3.72RR3846 pKa = 11.84IQLTKK3851 pKa = 10.64GRR3853 pKa = 11.84IVTFYY3858 pKa = 11.12NKK3860 pKa = 10.12LFPPVPNFEE3869 pKa = 4.38TVIKK3873 pKa = 10.04VHH3875 pKa = 5.5STVFQDD3881 pKa = 3.18NPTAEE3886 pKa = 4.35GEE3888 pKa = 4.24FFGIQLTSKK3897 pKa = 10.08HH3898 pKa = 6.3AEE3900 pKa = 3.96SCSIAGLWEE3909 pKa = 4.35LCCPGCQWRR3918 pKa = 11.84KK3919 pKa = 6.99TDD3921 pKa = 3.38MSIVEE3926 pKa = 4.35SVISLLLGIKK3936 pKa = 10.04DD3937 pKa = 3.61NSGMDD3942 pKa = 3.92RR3943 pKa = 11.84IEE3945 pKa = 4.55GDD3947 pKa = 3.06IPLEE3951 pKa = 4.15SEE3953 pKa = 5.11GIQQITFADD3962 pKa = 3.65LMEE3965 pKa = 4.74EE3966 pKa = 4.22EE3967 pKa = 5.04SVDD3970 pKa = 3.68AQSVFLDD3977 pKa = 3.56SQYY3980 pKa = 11.23TSGDD3984 pKa = 3.37VTFDD3988 pKa = 3.07WDD3990 pKa = 3.94DD3991 pKa = 3.12

Molecular weight: 455.76 kDa
Isoelectric point according different methods:

>tr|A0A076JVA5|A0A076JVA5_9VIRU Replicase (Fragment) OS=Issyk-Kul virus OX=1453408 PE=4 SV=1
KKK2 pKa = 10.23EEE4 pKa = 4.08GTRR7 pKa = 11.84QAAGNFSKKK16 pKa = 10.96KK17 pKa = 10.28DD18 pKa = 3.47RR19 pKa = 11.84HHH21 pKa = 4.35SMFNLKKK28 pKa = 9.35EEE30 pKa = 4.28YY31 pKa = 10.72VGCVILCHHH40 pKa = 6.53ADDD43 pKa = 4.29AWCGDDD49 pKa = 3.16SSHHH53 pKa = 5.52VPVHHH58 pKa = 6.42SSHHH62 pKa = 5.68KKK64 pKa = 10.61NTTTIQEEE72 pKa = 4.21RR73 pKa = 11.84NVTMVQKKK81 pKa = 10.73VTILPEEE88 pKa = 5.12IDDD91 pKa = 3.38KK92 pKa = 11.14EEE94 pKa = 4.03GTRR97 pKa = 11.84QAAGNFSGTLKKK109 pKa = 10.65KKK111 pKa = 9.47TYYY114 pKa = 9.17TNFSSPIGLFKKK126 pKa = 10.61WLHHH130 pKa = 6.38VTQSRR135 pKa = 11.84NKKK138 pKa = 8.23TTKKK142 pKa = 9.92SKKK145 pKa = 9.76QPVKKK150 pKa = 10.63KKK152 pKa = 9.94RR153 pKa = 11.84VDDD156 pKa = 3.5TLHHH160 pKa = 4.74RR161 pKa = 11.84GRR163 pKa = 11.84KKK165 pKa = 7.5EEE167 pKa = 4.09PSGKKK172 pKa = 7.97TKKK175 pKa = 10.11LSRR178 pKa = 11.84STRR181 pKa = 11.84ILTITGKKK189 pKa = 9.62SAMPTTGDDD198 pKa = 3.27EEE200 pKa = 4.83PGEEE204 pKa = 4.25TSTNQSMDDD213 pKa = 2.94SGNQTASLGLTTVVSVTSQNSTNTVAILTTSSVTKKK249 pKa = 10.48SSTEEE254 pKa = 3.68STPSSQQPNTTEEE267 pKa = 3.63AAVALQTNTPTTDDD281 pKa = 2.93PFISDDD287 pKa = 3.37TLTVPEEE294 pKa = 4.43TTSGHHH300 pKa = 6.44HH301 pKa = 5.36RR302 pKa = 11.84KKK304 pKa = 9.59LEEE307 pKa = 3.99VQNSSTEEE315 pKa = 4.09VDDD318 pKa = 3.52LTNSSVSAATPSAHHH333 pKa = 5.82TLALEEE339 pKa = 4.5SKKK342 pKa = 11.22PDDD345 pKa = 3.33TVAIAQNTTNATLKKK360 pKa = 8.9TSTTAAPSKKK370 pKa = 10.57EEE372 pKa = 3.89DDD374 pKa = 3.37KK375 pKa = 11.39VTPTNVSRR383 pKa = 11.84QRR385 pKa = 11.84RR386 pKa = 11.84KKK388 pKa = 7.92NDDD391 pKa = 2.85TRR393 pKa = 11.84MLHHH397 pKa = 5.37TVHHH401 pKa = 6.44PEEE404 pKa = 5.13DD405 pKa = 3.7SDDD408 pKa = 2.76STAEEE413 pKa = 3.8SVRR416 pKa = 11.84TMTNHHH422 pKa = 6.08VPAQYYY428 pKa = 10.92DDD430 pKa = 3.55NRR432 pKa = 11.84HHH434 pKa = 4.21EE435 pKa = 4.21TRR437 pKa = 11.84FFSLDDD443 pKa = 3.29DDD445 pKa = 4.06DDD447 pKa = 3.62WDDD450 pKa = 3.85YY451 pKa = 11.9KK452 pKa = 10.23TNLPGQRR459 pKa = 11.84VSIICAKKK467 pKa = 10.22ALEEE471 pKa = 4.31KKK473 pKa = 10.03GEEE476 pKa = 4.43YYY478 pKa = 10.37HHH480 pKa = 7.14EEE482 pKa = 5.31KKK484 pKa = 10.73DD485 pKa = 3.47WPSKKK490 pKa = 9.3SEEE493 pKa = 4.1LTACEEE499 pKa = 4.46ANTCPGTPVDDD510 pKa = 3.89KKK512 pKa = 11.0PNVNYYY518 pKa = 10.76DD519 pKa = 3.64IKKK522 pKa = 10.56MSTPDDD528 pKa = 3.53PVVIINYYY536 pKa = 7.53TTHHH540 pKa = 6.16YY541 pKa = 11.15FLDDD545 pKa = 3.88YY546 pKa = 11.87MMFHHH551 pKa = 7.14EEE553 pKa = 4.27RR554 pKa = 11.84GCLYYY559 pKa = 10.3IPIRR563 pKa = 11.84SNYYY567 pKa = 9.53WFLRR571 pKa = 11.84SEEE574 pKa = 4.46KK575 pKa = 10.42FSPVSTIVIEEE586 pKa = 4.54KKK588 pKa = 9.52LTAEEE593 pKa = 4.28KKK595 pKa = 10.43LMCAIKKK602 pKa = 10.22VGHHH606 pKa = 5.96EEE608 pKa = 4.04KKK610 pKa = 9.81TWKKK614 pKa = 10.48YY615 pKa = 9.52KKK617 pKa = 10.15PIRR620 pKa = 11.84IWFKKK625 pKa = 10.99DD626 pKa = 3.27DD627 pKa = 2.76TMGMRR632 pKa = 11.84KKK634 pKa = 9.24LSVQVKKK641 pKa = 8.64QTKKK645 pKa = 9.82KKK647 pKa = 9.27NTYYY651 pKa = 8.37HHH653 pKa = 6.31RR654 pKa = 11.84SHHH657 pKa = 7.41IPIEEE662 pKa = 3.78HHH664 pKa = 4.52LHHH667 pKa = 5.85KKK669 pKa = 9.06RR670 pKa = 11.84AVPRR674 pKa = 11.84PRR676 pKa = 11.84IAICNDDD683 pKa = 3.06VITEEE688 pKa = 4.34PLGQEEE694 pKa = 4.09HH695 pKa = 6.77CYYY698 pKa = 9.99VGKKK702 pKa = 10.22KKK704 pKa = 10.25HHH706 pKa = 5.18YY707 pKa = 10.11CTPEEE712 pKa = 3.84EE713 pKa = 4.32HH714 pKa = 6.71VQVPNEEE721 pKa = 4.04NITVSEEE728 pKa = 4.08CAAGEEE734 pKa = 4.26CFLVNLNGQGHHH746 pKa = 5.8SSAVVGHHH754 pKa = 5.9PSVKKK759 pKa = 9.82CLNSCMFKKK768 pKa = 10.56KKK770 pKa = 9.67KK771 pKa = 9.19SEEE774 pKa = 4.14DDD776 pKa = 3.51LFTCPGGKKK785 pKa = 7.09HHH787 pKa = 7.13VQTNVVDDD795 pKa = 4.16QCPMHHH801 pKa = 6.61EE802 pKa = 4.29LGRR805 pKa = 11.84AALYYY810 pKa = 9.59CRR812 pKa = 11.84ATYYY816 pKa = 9.97PKKK819 pKa = 10.92LYYY822 pKa = 7.54TLFWLTFGYYY832 pKa = 10.92CFCLVMEEE840 pKa = 4.27LKKK843 pKa = 9.81TVLITCKKK851 pKa = 10.57INFCMEEE858 pKa = 3.97KK859 pKa = 10.2DDD861 pKa = 3.74KK862 pKa = 10.06RR863 pKa = 11.84GYYY866 pKa = 10.59EEE868 pKa = 4.07HH869 pKa = 7.05KKK871 pKa = 10.52WVNSYYY877 pKa = 8.77EEE879 pKa = 3.86WDDD882 pKa = 3.65HH883 pKa = 6.67KK884 pKa = 10.82CCACKKK890 pKa = 10.52PFCSLSFARR899 pKa = 11.84RR900 pKa = 11.84EEE902 pKa = 4.23PRR904 pKa = 11.84HHH906 pKa = 5.74EEE908 pKa = 4.04EE909 pKa = 4.14TSRR912 pKa = 11.84SVKKK916 pKa = 10.54EEE918 pKa = 4.16INAVLAVRR926 pKa = 11.84RR927 pKa = 11.84TPRR930 pKa = 11.84ILIWIAVALTRR941 pKa = 11.84YYY943 pKa = 8.86KKK945 pKa = 9.83VCRR948 pKa = 11.84LSWATVLIVMCLLIISPVQGLKKK971 pKa = 9.63GPLPDDD977 pKa = 5.37IWDDD981 pKa = 3.68EE982 pKa = 4.6YY983 pKa = 10.69EE984 pKa = 4.59EEE986 pKa = 4.04LNCKKK991 pKa = 8.68EE992 pKa = 4.04CIKKK996 pKa = 10.88LDDD999 pKa = 3.71CICEEE1004 pKa = 4.64DD1005 pKa = 3.67DDD1007 pKa = 4.38HH1008 pKa = 6.83SKKK1011 pKa = 10.02EEE1013 pKa = 3.75STMRR1017 pKa = 11.84KKK1019 pKa = 8.8SSVVVQGPTPSQPEEE1034 pKa = 4.14KK1035 pKa = 9.63HHH1037 pKa = 7.02ILKKK1041 pKa = 10.13IDDD1044 pKa = 3.29EEE1046 pKa = 4.52PWGTLHHH1053 pKa = 6.92PEEE1056 pKa = 5.71YYY1058 pKa = 10.34PAQSAKKK1065 pKa = 10.03HH1066 pKa = 6.33SLTWEEE1072 pKa = 3.76SQAVGDDD1079 pKa = 4.26KK1080 pKa = 10.36VLSGRR1085 pKa = 11.84SSTVLKKK1092 pKa = 10.83EEE1094 pKa = 4.73KKK1096 pKa = 9.87STVWTMEEE1104 pKa = 3.91KKK1106 pKa = 9.41EE1107 pKa = 4.03SEEE1110 pKa = 4.2KK1111 pKa = 9.55KK1112 pKa = 8.86LTISILDDD1120 pKa = 3.48TQIYYY1125 pKa = 9.8AEEE1128 pKa = 3.9LYYY1131 pKa = 9.6TGDDD1135 pKa = 3.73NIKKK1139 pKa = 7.64WSEEE1143 pKa = 4.45SCSGDDD1149 pKa = 3.3PLNCGCNTQTCHHH1162 pKa = 5.17QNWMNVRR1169 pKa = 11.84NWRR1172 pKa = 11.84CNPTWCWRR1180 pKa = 11.84VGTGCSCCASDDD1192 pKa = 4.25TEEE1195 pKa = 5.68YYY1197 pKa = 10.69DDD1199 pKa = 4.15LATIWKKK1206 pKa = 9.31EEE1208 pKa = 4.09HH1209 pKa = 6.77KK1210 pKa = 8.62KK1211 pKa = 7.73AVIACVEEE1219 pKa = 4.08DDD1221 pKa = 3.17HH1222 pKa = 6.13EE1223 pKa = 4.32RR1224 pKa = 11.84VCEEE1228 pKa = 4.09VEEE1231 pKa = 3.97GVEEE1235 pKa = 4.25QLGPVKKK1242 pKa = 11.0EEE1244 pKa = 4.17SDDD1247 pKa = 4.11FGEEE1251 pKa = 4.19QILNQRR1257 pKa = 11.84IALFHHH1263 pKa = 6.6KK1264 pKa = 8.51PKKK1267 pKa = 9.96STHHH1271 pKa = 6.32DDD1273 pKa = 3.36FHHH1276 pKa = 7.11FGVTSATSFCNIEEE1290 pKa = 4.28CTHHH1294 pKa = 5.34TVGDDD1299 pKa = 3.88YY1300 pKa = 10.62IYYY1303 pKa = 10.56DD1304 pKa = 3.54DDD1306 pKa = 4.12FVLDDD1311 pKa = 4.73DD1312 pKa = 3.85TSANYYY1318 pKa = 9.13KKK1320 pKa = 11.13KK1321 pKa = 10.68NNKKK1325 pKa = 6.97RR1326 pKa = 11.84VWMSWEEE1333 pKa = 4.75ISVSYYY1339 pKa = 10.08YY1340 pKa = 10.51NPGDDD1345 pKa = 3.4TTCVTDDD1352 pKa = 5.26IVEEE1356 pKa = 4.26NSEEE1360 pKa = 3.79FANVFKKK1367 pKa = 11.34EEE1369 pKa = 4.27NYYY1372 pKa = 9.41TTHHH1376 pKa = 6.42FHHH1379 pKa = 7.06SRR1381 pKa = 11.84VVSEEE1386 pKa = 4.38KKK1388 pKa = 10.3LSLDDD1393 pKa = 3.93KKK1395 pKa = 10.84RR1396 pKa = 11.84PLSSGGDDD1404 pKa = 2.92TAYYY1408 pKa = 8.49TVDDD1412 pKa = 3.19LEEE1415 pKa = 4.59YYY1417 pKa = 10.69KKK1419 pKa = 9.99EE1420 pKa = 3.61HHH1422 pKa = 7.04EEE1424 pKa = 3.8LKKK1427 pKa = 10.15SMGSCTGCFACNLGATCSFTLAIRR1451 pKa = 11.84RR1452 pKa = 11.84PEEE1455 pKa = 3.92FNLHHH1460 pKa = 5.67TSDDD1464 pKa = 3.56AGVVVPDDD1472 pKa = 3.4SFLVEEE1478 pKa = 3.66DDD1480 pKa = 3.53FNTYYY1485 pKa = 10.02IKKK1488 pKa = 10.2FSVEEE1493 pKa = 3.83KK1494 pKa = 9.83DD1495 pKa = 3.32NVCIKKK1501 pKa = 10.18LEEE1504 pKa = 4.38KKK1506 pKa = 9.25CKKK1509 pKa = 9.61CPKKK1513 pKa = 10.1EE1514 pKa = 3.9LVACKKK1520 pKa = 10.03FSFEEE1525 pKa = 3.86PKKK1528 pKa = 10.18EE1529 pKa = 3.92ALEEE1533 pKa = 3.84HH1534 pKa = 7.01STIFAKKK1541 pKa = 9.49TQSCGNSTLSCMLSGTKKK1559 pKa = 10.19FFSGIGGFFNGYYY1572 pKa = 9.26GSILKKK1578 pKa = 10.74ILSTVLPIALIVLTIFFGPKKK1599 pKa = 9.66SFVLRR1604 pKa = 11.84LCKKK1608 pKa = 10.01KK1609 pKa = 9.84RR1610 pKa = 11.84ALKKK1614 pKa = 10.15LSYYY1618 pKa = 11.06EE1619 pKa = 3.87MKKK1622 pKa = 10.78ITDDD1626 pKa = 2.86DDD1628 pKa = 3.88EE1629 pKa = 4.34LKKK1632 pKa = 10.97KK1633 pKa = 8.93EE1634 pKa = 4.13SSDDD1638 pKa = 3.11EE1639 pKa = 4.08KKK1641 pKa = 10.31FLKKK1645 pKa = 10.79VLGPKKK1651 pKa = 10.1KKK1653 pKa = 10.21A

Molecular weight: 183.68 kDa
Isoelectric point according different methods:

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ArgC ESI

LysN ESI

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Try MALDI

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ArgC MALDI

LysN MALDI

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Try LTQ

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ArgC LTQ

LysN LTQ

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Try MSlow

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ArgC MSlow

LysN MSlow

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Try MShigh

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ArgC MShigh

LysN MShigh

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For dipeptide frequency statistics click here

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