Amino acid dipepetide frequency for Tenacibaculum todarodis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.65AlaAla: 3.65 ± 0.102	0.518AlaCys: 0.518 ± 0.041	3.205AlaAsp: 3.205 ± 0.11	3.872AlaGlu: 3.872 ± 0.086	3.197AlaPhe: 3.197 ± 0.068	4.096AlaGly: 4.096 ± 0.182	0.969AlaHis: 0.969 ± 0.039	5.543AlaIle: 5.543 ± 0.096	5.133AlaLys: 5.133 ± 0.11	5.569AlaLeu: 5.569 ± 0.103	1.322AlaMet: 1.322 ± 0.05	3.583AlaAsn: 3.583 ± 0.072	1.758AlaPro: 1.758 ± 0.073	2.12AlaGln: 2.12 ± 0.054	1.768AlaArg: 1.768 ± 0.043	4.219AlaSer: 4.219 ± 0.105	4.204AlaThr: 4.204 ± 0.248	3.989AlaVal: 3.989 ± 0.079	0.492AlaTrp: 0.492 ± 0.025	2.132AlaTyr: 2.132 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.406CysAla: 0.406 ± 0.023	0.091CysCys: 0.091 ± 0.012	0.409CysAsp: 0.409 ± 0.044	0.397CysGlu: 0.397 ± 0.022	0.368CysPhe: 0.368 ± 0.022	0.58CysGly: 0.58 ± 0.029	0.153CysHis: 0.153 ± 0.014	0.509CysIle: 0.509 ± 0.023	0.551CysLys: 0.551 ± 0.026	0.564CysLeu: 0.564 ± 0.022	0.128CysMet: 0.128 ± 0.013	0.416CysAsn: 0.416 ± 0.024	0.337CysPro: 0.337 ± 0.031	0.188CysGln: 0.188 ± 0.016	0.17CysArg: 0.17 ± 0.015	0.517CysSer: 0.517 ± 0.041	0.375CysThr: 0.375 ± 0.021	0.435CysVal: 0.435 ± 0.025	0.054CysTrp: 0.054 ± 0.009	0.215CysTyr: 0.215 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.872AspAla: 3.872 ± 0.122	0.38AspCys: 0.38 ± 0.023	2.895AspAsp: 2.895 ± 0.186	3.807AspGlu: 3.807 ± 0.128	3.667AspPhe: 3.667 ± 0.073	3.493AspGly: 3.493 ± 0.158	0.634AspHis: 0.634 ± 0.031	4.251AspIle: 4.251 ± 0.068	4.656AspLys: 4.656 ± 0.102	4.852AspLeu: 4.852 ± 0.104	0.937AspMet: 0.937 ± 0.038	3.474AspAsn: 3.474 ± 0.159	1.498AspPro: 1.498 ± 0.146	1.124AspGln: 1.124 ± 0.04	1.533AspArg: 1.533 ± 0.052	3.06AspSer: 3.06 ± 0.085	2.994AspThr: 2.994 ± 0.168	3.885AspVal: 3.885 ± 0.167	0.66AspTrp: 0.66 ± 0.032	2.523AspTyr: 2.523 ± 0.082	0.0AspXaa: 0.0 ± 0.0
Glu	4.176GluAla: 4.176 ± 0.095	0.362GluCys: 0.362 ± 0.04	3.61GluAsp: 3.61 ± 0.112	5.19GluGlu: 5.19 ± 0.107	3.146GluPhe: 3.146 ± 0.072	3.527GluGly: 3.527 ± 0.07	1.038GluHis: 1.038 ± 0.039	5.945GluIle: 5.945 ± 0.098	6.493GluLys: 6.493 ± 0.129	6.202GluLeu: 6.202 ± 0.089	1.476GluMet: 1.476 ± 0.044	5.405GluAsn: 5.405 ± 0.093	1.405GluPro: 1.405 ± 0.043	2.133GluGln: 2.133 ± 0.06	2.223GluArg: 2.223 ± 0.069	3.203GluSer: 3.203 ± 0.061	3.835GluThr: 3.835 ± 0.083	4.418GluVal: 4.418 ± 0.078	0.531GluTrp: 0.531 ± 0.023	2.366GluTyr: 2.366 ± 0.059	0.0GluXaa: 0.0 ± 0.0
Phe	2.946PheAla: 2.946 ± 0.07	0.426PheCys: 0.426 ± 0.023	3.225PheAsp: 3.225 ± 0.072	3.31PheGlu: 3.31 ± 0.076	2.959PhePhe: 2.959 ± 0.094	3.807PheGly: 3.807 ± 0.099	0.767PheHis: 0.767 ± 0.029	4.213PheIle: 4.213 ± 0.106	4.421PheLys: 4.421 ± 0.102	5.013PheLeu: 5.013 ± 0.119	1.069PheMet: 1.069 ± 0.042	3.606PheAsn: 3.606 ± 0.09	1.656PhePro: 1.656 ± 0.06	1.476PheGln: 1.476 ± 0.046	1.47PheArg: 1.47 ± 0.049	4.359PheSer: 4.359 ± 0.099	3.373PheThr: 3.373 ± 0.072	2.964PheVal: 2.964 ± 0.063	0.568PheTrp: 0.568 ± 0.027	2.224PheTyr: 2.224 ± 0.067	0.0PheXaa: 0.0 ± 0.0
Gly	3.937GlyAla: 3.937 ± 0.094	0.525GlyCys: 0.525 ± 0.029	3.311GlyAsp: 3.311 ± 0.186	3.594GlyGlu: 3.594 ± 0.108	3.728GlyPhe: 3.728 ± 0.083	4.453GlyGly: 4.453 ± 0.114	1.004GlyHis: 1.004 ± 0.036	5.214GlyIle: 5.214 ± 0.08	5.353GlyLys: 5.353 ± 0.107	5.479GlyLeu: 5.479 ± 0.126	1.414GlyMet: 1.414 ± 0.044	3.987GlyAsn: 3.987 ± 0.107	1.143GlyPro: 1.143 ± 0.048	1.583GlyGln: 1.583 ± 0.048	1.957GlyArg: 1.957 ± 0.066	3.721GlySer: 3.721 ± 0.09	4.21GlyThr: 4.21 ± 0.259	4.375GlyVal: 4.375 ± 0.127	0.564GlyTrp: 0.564 ± 0.027	2.485GlyTyr: 2.485 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	0.86HisAla: 0.86 ± 0.032	0.154HisCys: 0.154 ± 0.013	0.663HisAsp: 0.663 ± 0.026	0.79HisGlu: 0.79 ± 0.034	1.063HisPhe: 1.063 ± 0.037	0.892HisGly: 0.892 ± 0.039	0.421HisHis: 0.421 ± 0.025	1.332HisIle: 1.332 ± 0.049	1.302HisLys: 1.302 ± 0.049	1.634HisLeu: 1.634 ± 0.054	0.259HisMet: 0.259 ± 0.015	0.953HisAsn: 0.953 ± 0.037	0.828HisPro: 0.828 ± 0.035	0.711HisGln: 0.711 ± 0.03	0.554HisArg: 0.554 ± 0.029	0.968HisSer: 0.968 ± 0.038	0.945HisThr: 0.945 ± 0.036	0.818HisVal: 0.818 ± 0.035	0.158HisTrp: 0.158 ± 0.014	0.682HisTyr: 0.682 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.551IleAla: 5.551 ± 0.101	0.621IleCys: 0.621 ± 0.028	5.028IleAsp: 5.028 ± 0.09	5.655IleGlu: 5.655 ± 0.11	3.73IlePhe: 3.73 ± 0.085	5.051IleGly: 5.051 ± 0.085	1.331IleHis: 1.331 ± 0.043	6.327IleIle: 6.327 ± 0.127	6.679IleLys: 6.679 ± 0.118	7.236IleLeu: 7.236 ± 0.132	1.299IleMet: 1.299 ± 0.043	5.4IleAsn: 5.4 ± 0.098	3.192IlePro: 3.192 ± 0.078	2.475IleGln: 2.475 ± 0.06	2.348IleArg: 2.348 ± 0.061	5.973IleSer: 5.973 ± 0.092	5.206IleThr: 5.206 ± 0.11	4.935IleVal: 4.935 ± 0.093	0.657IleTrp: 0.657 ± 0.027	2.678IleTyr: 2.678 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	5.022LysAla: 5.022 ± 0.106	0.335LysCys: 0.335 ± 0.021	4.851LysAsp: 4.851 ± 0.107	7.314LysGlu: 7.314 ± 0.145	3.392LysPhe: 3.392 ± 0.091	4.876LysGly: 4.876 ± 0.103	1.537LysHis: 1.537 ± 0.053	7.149LysIle: 7.149 ± 0.131	8.565LysLys: 8.565 ± 0.177	7.221LysLeu: 7.221 ± 0.132	2.292LysMet: 2.292 ± 0.063	6.46LysAsn: 6.46 ± 0.142	2.546LysPro: 2.546 ± 0.068	2.976LysGln: 2.976 ± 0.079	2.996LysArg: 2.996 ± 0.069	4.933LysSer: 4.933 ± 0.116	5.387LysThr: 5.387 ± 0.096	5.146LysVal: 5.146 ± 0.1	0.825LysTrp: 0.825 ± 0.032	3.322LysTyr: 3.322 ± 0.086	0.0LysXaa: 0.0 ± 0.0
Leu	5.504LeuAla: 5.504 ± 0.107	0.514LeuCys: 0.514 ± 0.024	4.955LeuAsp: 4.955 ± 0.09	6.18LeuGlu: 6.18 ± 0.13	4.916LeuPhe: 4.916 ± 0.126	5.633LeuGly: 5.633 ± 0.112	1.51LeuHis: 1.51 ± 0.049	7.053LeuIle: 7.053 ± 0.146	8.388LeuLys: 8.388 ± 0.158	8.459LeuLeu: 8.459 ± 0.177	1.81LeuMet: 1.81 ± 0.054	5.687LeuAsn: 5.687 ± 0.106	3.399LeuPro: 3.399 ± 0.063	3.284LeuGln: 3.284 ± 0.083	2.756LeuArg: 2.756 ± 0.061	6.417LeuSer: 6.417 ± 0.087	5.348LeuThr: 5.348 ± 0.182	5.253LeuVal: 5.253 ± 0.1	0.68LeuTrp: 0.68 ± 0.028	2.885LeuTyr: 2.885 ± 0.082	0.0LeuXaa: 0.0 ± 0.0
Met	1.412MetAla: 1.412 ± 0.045	0.139MetCys: 0.139 ± 0.014	0.957MetAsp: 0.957 ± 0.032	1.147MetGlu: 1.147 ± 0.041	0.883MetPhe: 0.883 ± 0.033	1.177MetGly: 1.177 ± 0.043	0.349MetHis: 0.349 ± 0.02	1.48MetIle: 1.48 ± 0.05	2.168MetLys: 2.168 ± 0.061	1.848MetLeu: 1.848 ± 0.05	0.5MetMet: 0.5 ± 0.028	1.32MetAsn: 1.32 ± 0.04	0.727MetPro: 0.727 ± 0.028	0.772MetGln: 0.772 ± 0.031	0.808MetArg: 0.808 ± 0.037	1.313MetSer: 1.313 ± 0.043	1.027MetThr: 1.027 ± 0.038	1.178MetVal: 1.178 ± 0.04	0.133MetTrp: 0.133 ± 0.012	0.69MetTyr: 0.69 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	3.976AsnAla: 3.976 ± 0.101	0.454AsnCys: 0.454 ± 0.025	3.318AsnAsp: 3.318 ± 0.103	3.827AsnGlu: 3.827 ± 0.068	3.497AsnPhe: 3.497 ± 0.078	4.177AsnGly: 4.177 ± 0.125	1.013AsnHis: 1.013 ± 0.039	5.167AsnIle: 5.167 ± 0.1	5.423AsnLys: 5.423 ± 0.118	5.962AsnLeu: 5.962 ± 0.102	1.224AsnMet: 1.224 ± 0.046	4.754AsnAsn: 4.754 ± 0.146	2.919AsnPro: 2.919 ± 0.088	2.37AsnGln: 2.37 ± 0.065	2.009AsnArg: 2.009 ± 0.061	4.515AsnSer: 4.515 ± 0.093	4.24AsnThr: 4.24 ± 0.101	3.958AsnVal: 3.958 ± 0.077	0.815AsnTrp: 0.815 ± 0.033	3.125AsnTyr: 3.125 ± 0.068	0.0AsnXaa: 0.0 ± 0.0
Pro	1.757ProAla: 1.757 ± 0.085	0.2ProCys: 0.2 ± 0.018	1.648ProAsp: 1.648 ± 0.082	2.429ProGlu: 2.429 ± 0.058	1.86ProPhe: 1.86 ± 0.05	1.682ProGly: 1.682 ± 0.104	0.566ProHis: 0.566 ± 0.028	2.701ProIle: 2.701 ± 0.077	2.826ProLys: 2.826 ± 0.074	2.627ProLeu: 2.627 ± 0.064	0.679ProMet: 0.679 ± 0.035	2.35ProAsn: 2.35 ± 0.084	0.684ProPro: 0.684 ± 0.035	1.011ProGln: 1.011 ± 0.04	0.815ProArg: 0.815 ± 0.032	2.094ProSer: 2.094 ± 0.081	2.472ProThr: 2.472 ± 0.211	2.139ProVal: 2.139 ± 0.094	0.291ProTrp: 0.291 ± 0.02	1.162ProTyr: 1.162 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	1.722GlnAla: 1.722 ± 0.054	0.158GlnCys: 0.158 ± 0.014	1.551GlnAsp: 1.551 ± 0.065	2.398GlnGlu: 2.398 ± 0.063	1.816GlnPhe: 1.816 ± 0.052	1.615GlnGly: 1.615 ± 0.067	0.573GlnHis: 0.573 ± 0.029	2.573GlnIle: 2.573 ± 0.056	3.085GlnLys: 3.085 ± 0.082	3.24GlnLeu: 3.24 ± 0.074	0.686GlnMet: 0.686 ± 0.031	2.152GlnAsn: 2.152 ± 0.072	1.007GlnPro: 1.007 ± 0.04	1.549GlnGln: 1.549 ± 0.054	1.09GlnArg: 1.09 ± 0.041	1.672GlnSer: 1.672 ± 0.044	1.923GlnThr: 1.923 ± 0.05	1.911GlnVal: 1.911 ± 0.051	0.275GlnTrp: 0.275 ± 0.017	1.213GlnTyr: 1.213 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	1.859ArgAla: 1.859 ± 0.063	0.162ArgCys: 0.162 ± 0.013	1.5ArgAsp: 1.5 ± 0.048	2.02ArgGlu: 2.02 ± 0.058	1.794ArgPhe: 1.794 ± 0.052	1.828ArgGly: 1.828 ± 0.053	0.479ArgHis: 0.479 ± 0.023	2.595ArgIle: 2.595 ± 0.065	2.874ArgLys: 2.874 ± 0.07	2.747ArgLeu: 2.747 ± 0.068	0.774ArgMet: 0.774 ± 0.033	2.064ArgAsn: 2.064 ± 0.055	0.914ArgPro: 0.914 ± 0.035	0.933ArgGln: 0.933 ± 0.038	1.168ArgArg: 1.168 ± 0.052	1.706ArgSer: 1.706 ± 0.054	1.713ArgThr: 1.713 ± 0.048	1.951ArgVal: 1.951 ± 0.054	0.292ArgTrp: 0.292 ± 0.02	1.268ArgTyr: 1.268 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	3.765SerAla: 3.765 ± 0.096	0.585SerCys: 0.585 ± 0.028	3.494SerAsp: 3.494 ± 0.118	4.338SerGlu: 4.338 ± 0.08	4.046SerPhe: 4.046 ± 0.103	4.42SerGly: 4.42 ± 0.134	0.948SerHis: 0.948 ± 0.033	5.279SerIle: 5.279 ± 0.099	5.574SerLys: 5.574 ± 0.119	5.979SerLeu: 5.979 ± 0.094	1.149SerMet: 1.149 ± 0.039	4.035SerAsn: 4.035 ± 0.103	1.972SerPro: 1.972 ± 0.084	1.95SerGln: 1.95 ± 0.055	1.796SerArg: 1.796 ± 0.049	4.377SerSer: 4.377 ± 0.114	3.776SerThr: 3.776 ± 0.12	4.152SerVal: 4.152 ± 0.083	0.742SerTrp: 0.742 ± 0.032	2.683SerTyr: 2.683 ± 0.064	0.0SerXaa: 0.0 ± 0.0
Thr	4.07ThrAla: 4.07 ± 0.334	0.373ThrCys: 0.373 ± 0.03	3.503ThrAsp: 3.503 ± 0.181	3.773ThrGlu: 3.773 ± 0.122	3.315ThrPhe: 3.315 ± 0.11	3.951ThrGly: 3.951 ± 0.166	0.963ThrHis: 0.963 ± 0.034	5.849ThrIle: 5.849 ± 0.283	4.633ThrLys: 4.633 ± 0.086	5.468ThrLeu: 5.468 ± 0.14	0.9ThrMet: 0.9 ± 0.039	3.813ThrAsn: 3.813 ± 0.105	2.7ThrPro: 2.7 ± 0.156	1.97ThrGln: 1.97 ± 0.074	1.567ThrArg: 1.567 ± 0.051	4.25ThrSer: 4.25 ± 0.147	4.33ThrThr: 4.33 ± 0.41	4.359ThrVal: 4.359 ± 0.364	0.575ThrTrp: 0.575 ± 0.047	2.335ThrTyr: 2.335 ± 0.075	0.0ThrXaa: 0.0 ± 0.0
Val	4.214ValAla: 4.214 ± 0.081	0.469ValCys: 0.469 ± 0.027	3.631ValAsp: 3.631 ± 0.106	4.104ValGlu: 4.104 ± 0.106	3.542ValPhe: 3.542 ± 0.079	3.87ValGly: 3.87 ± 0.081	0.897ValHis: 0.897 ± 0.036	4.832ValIle: 4.832 ± 0.088	4.761ValLys: 4.761 ± 0.102	6.064ValLeu: 6.064 ± 0.091	1.185ValMet: 1.185 ± 0.041	3.839ValAsn: 3.839 ± 0.083	1.861ValPro: 1.861 ± 0.055	1.718ValGln: 1.718 ± 0.051	1.838ValArg: 1.838 ± 0.057	4.627ValSer: 4.627 ± 0.087	4.331ValThr: 4.331 ± 0.492	4.319ValVal: 4.319 ± 0.12	0.572ValTrp: 0.572 ± 0.036	2.18ValTyr: 2.18 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.533TrpAla: 0.533 ± 0.028	0.083TrpCys: 0.083 ± 0.01	0.474TrpAsp: 0.474 ± 0.024	0.583TrpGlu: 0.583 ± 0.028	0.572TrpPhe: 0.572 ± 0.028	0.567TrpGly: 0.567 ± 0.025	0.18TrpHis: 0.18 ± 0.013	0.663TrpIle: 0.663 ± 0.03	0.831TrpLys: 0.831 ± 0.037	0.945TrpLeu: 0.945 ± 0.04	0.292TrpMet: 0.292 ± 0.021	0.688TrpAsn: 0.688 ± 0.033	0.158TrpPro: 0.158 ± 0.013	0.369TrpGln: 0.369 ± 0.02	0.353TrpArg: 0.353 ± 0.02	0.529TrpSer: 0.529 ± 0.026	0.546TrpThr: 0.546 ± 0.055	0.519TrpVal: 0.519 ± 0.024	0.13TrpTrp: 0.13 ± 0.013	0.418TrpTyr: 0.418 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.108TyrAla: 2.108 ± 0.058	0.314TyrCys: 0.314 ± 0.027	1.965TyrAsp: 1.965 ± 0.053	1.957TyrGlu: 1.957 ± 0.048	2.363TyrPhe: 2.363 ± 0.075	2.342TyrGly: 2.342 ± 0.069	0.655TyrHis: 0.655 ± 0.027	2.696TyrIle: 2.696 ± 0.066	3.426TyrLys: 3.426 ± 0.08	3.523TyrLeu: 3.523 ± 0.079	0.631TyrMet: 0.631 ± 0.028	2.758TyrAsn: 2.758 ± 0.066	1.289TyrPro: 1.289 ± 0.044	1.5TyrGln: 1.5 ± 0.046	1.42TyrArg: 1.42 ± 0.05	2.607TyrSer: 2.607 ± 0.068	2.459TyrThr: 2.459 ± 0.107	2.151TyrVal: 2.151 ± 0.066	0.423TyrTrp: 0.423 ± 0.026	1.648TyrTyr: 1.648 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2636 proteins (903262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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