Human papillomavirus 154

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 11

Average proteome isoelectric point is 6.24

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|R9QBU3|R9QBU3_9PAPI Major capsid protein L1 OS=Human papillomavirus 154 OX=1195796 GN=L1 PE=3 SV=1
MM1 pKa = 7.28MGQTVTLKK9 pKa = 10.49DD10 pKa = 3.37IEE12 pKa = 4.49LGEE15 pKa = 4.19PLEE18 pKa = 4.36DD19 pKa = 3.46LVMPAHH25 pKa = 6.93LLCEE29 pKa = 4.28EE30 pKa = 4.73EE31 pKa = 4.81SLSSDD36 pKa = 3.28DD37 pKa = 3.91TPEE40 pKa = 4.15EE41 pKa = 4.26EE42 pKa = 4.82SLSPYY47 pKa = 10.42QVDD50 pKa = 4.78TICNSCNKK58 pKa = 10.24RR59 pKa = 11.84IRR61 pKa = 11.84LCVLATTGAIHH72 pKa = 7.33LLEE75 pKa = 3.86QLLFHH80 pKa = 7.18DD81 pKa = 5.32LSLVCPHH88 pKa = 7.28CSRR91 pKa = 11.84DD92 pKa = 3.32ILRR95 pKa = 11.84HH96 pKa = 4.98GRR98 pKa = 11.84THH100 pKa = 7.09

Molecular weight: 11.23 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|R9QBU2|R9QBU2_9PAPI Protein E7 OS=Human papillomavirus 154 OX=1195796 GN=E7 PE=3 SV=1
MM1 pKa = 6.96NQNDD5 pKa = 3.41LRR7 pKa = 11.84EE8 pKa = 4.28RR9 pKa = 11.84LDD11 pKa = 3.72ALQEE15 pKa = 4.03QLMTLYY21 pKa = 10.65EE22 pKa = 4.67LGPTDD27 pKa = 4.5LSSQIKK33 pKa = 9.96HH34 pKa = 4.91YY35 pKa = 10.56QLLRR39 pKa = 11.84KK40 pKa = 9.61EE41 pKa = 4.53SVLEE45 pKa = 3.79YY46 pKa = 9.75YY47 pKa = 10.17ARR49 pKa = 11.84KK50 pKa = 9.55EE51 pKa = 4.12GYY53 pKa = 9.04EE54 pKa = 3.98VLGLHH59 pKa = 6.62HH60 pKa = 7.21LPVLKK65 pKa = 10.76VSEE68 pKa = 4.69HH69 pKa = 5.67NAKK72 pKa = 9.86QAIKK76 pKa = 9.71MILHH80 pKa = 6.75LEE82 pKa = 4.13SLAKK86 pKa = 9.83SAYY89 pKa = 9.31KK90 pKa = 10.62HH91 pKa = 5.27EE92 pKa = 4.35TWTLNDD98 pKa = 3.32TSADD102 pKa = 3.31RR103 pKa = 11.84FMSPPRR109 pKa = 11.84NCFKK113 pKa = 10.69KK114 pKa = 10.55DD115 pKa = 3.39SFEE118 pKa = 4.03VTVWFDD124 pKa = 3.93HH125 pKa = 6.16NPQNAFPYY133 pKa = 10.45INWKK137 pKa = 8.35WIYY140 pKa = 10.29YY141 pKa = 9.44QDD143 pKa = 5.88NNDD146 pKa = 3.09QWHH149 pKa = 6.23KK150 pKa = 10.53VPGRR154 pKa = 11.84TDD156 pKa = 3.08HH157 pKa = 6.55NGLYY161 pKa = 10.37FIEE164 pKa = 5.05HH165 pKa = 7.62DD166 pKa = 3.6NTVTYY171 pKa = 10.41FLLFAKK177 pKa = 10.44DD178 pKa = 3.2AEE180 pKa = 4.63RR181 pKa = 11.84YY182 pKa = 9.36GKK184 pKa = 8.26TKK186 pKa = 10.04EE187 pKa = 3.67WTVNIGNEE195 pKa = 4.23QILPPSVTSSSRR207 pKa = 11.84RR208 pKa = 11.84SLSDD212 pKa = 3.12SPEE215 pKa = 4.09VNRR218 pKa = 11.84GASTSTYY225 pKa = 11.16AEE227 pKa = 3.9AEE229 pKa = 4.1EE230 pKa = 4.13EE231 pKa = 4.01NRR233 pKa = 11.84RR234 pKa = 11.84GSLQPQTTSPSTTTYY249 pKa = 9.75SPSRR253 pKa = 11.84RR254 pKa = 11.84RR255 pKa = 11.84RR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84GQGEE262 pKa = 4.14STTNKK267 pKa = 8.67RR268 pKa = 11.84RR269 pKa = 11.84RR270 pKa = 11.84RR271 pKa = 11.84AEE273 pKa = 3.74RR274 pKa = 11.84DD275 pKa = 2.98GGADD279 pKa = 2.99TVSPDD284 pKa = 3.43EE285 pKa = 4.51VGQSHH290 pKa = 5.71QLVRR294 pKa = 11.84STGLTRR300 pKa = 11.84TEE302 pKa = 3.97RR303 pKa = 11.84LKK305 pKa = 11.21EE306 pKa = 3.89EE307 pKa = 4.7AKK309 pKa = 10.77DD310 pKa = 3.69PPIVSISGPANKK322 pKa = 9.8LKK324 pKa = 10.19CWRR327 pKa = 11.84YY328 pKa = 9.06RR329 pKa = 11.84CGLKK333 pKa = 9.38TSKK336 pKa = 10.57NYY338 pKa = 10.34TYY340 pKa = 10.06MSSVFKK346 pKa = 10.46WITGDD351 pKa = 3.21VGLGDD356 pKa = 3.68GRR358 pKa = 11.84MLVAFANTQQRR369 pKa = 11.84NQFINALTLPKK380 pKa = 10.75DD381 pKa = 3.3MSYY384 pKa = 11.41CLGNLEE390 pKa = 4.54KK391 pKa = 10.97LL392 pKa = 3.77

Molecular weight: 45.22 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2422

100

606

346.0

39.3

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.202 ± 0.443

2.271 ± 0.709

6.4 ± 0.302

6.235 ± 0.586

4.707 ± 0.61

5.326 ± 0.745

2.147 ± 0.395

5.822 ± 0.921

5.285 ± 0.701

9.29 ± 1.154

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.982 ± 0.283

5.409 ± 0.63

6.482 ± 0.826

4.583 ± 0.372

5.615 ± 0.685

7.019 ± 0.707

6.358 ± 0.469

5.202 ± 0.61

1.239 ± 0.237

3.427 ± 0.447
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski