Amino acid dipepetide frequency for Jatrophihabitans sp. GAS493

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.262AlaAla: 20.262 ± 0.184	0.888AlaCys: 0.888 ± 0.026	7.93AlaAsp: 7.93 ± 0.088	7.534AlaGlu: 7.534 ± 0.096	3.459AlaPhe: 3.459 ± 0.061	12.19AlaGly: 12.19 ± 0.137	2.422AlaHis: 2.422 ± 0.045	5.522AlaIle: 5.522 ± 0.074	3.117AlaLys: 3.117 ± 0.063	12.886AlaLeu: 12.886 ± 0.123	2.427AlaMet: 2.427 ± 0.048	2.948AlaAsn: 2.948 ± 0.067	6.302AlaPro: 6.302 ± 0.1	4.363AlaGln: 4.363 ± 0.059	8.452AlaArg: 8.452 ± 0.116	7.711AlaSer: 7.711 ± 0.151	8.767AlaThr: 8.767 ± 0.186	11.187AlaVal: 11.187 ± 0.105	1.513AlaTrp: 1.513 ± 0.038	2.307AlaTyr: 2.307 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.941CysAla: 0.941 ± 0.028	0.09CysCys: 0.09 ± 0.007	0.444CysAsp: 0.444 ± 0.019	0.36CysGlu: 0.36 ± 0.016	0.22CysPhe: 0.22 ± 0.012	0.826CysGly: 0.826 ± 0.027	0.162CysHis: 0.162 ± 0.011	0.27CysIle: 0.27 ± 0.015	0.12CysLys: 0.12 ± 0.009	0.688CysLeu: 0.688 ± 0.026	0.113CysMet: 0.113 ± 0.01	0.152CysAsn: 0.152 ± 0.011	0.434CysPro: 0.434 ± 0.022	0.189CysGln: 0.189 ± 0.013	0.457CysArg: 0.457 ± 0.022	0.549CysSer: 0.549 ± 0.02	0.524CysThr: 0.524 ± 0.027	0.605CysVal: 0.605 ± 0.021	0.109CysTrp: 0.109 ± 0.01	0.153CysTyr: 0.153 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.381AspAla: 7.381 ± 0.079	0.382AspCys: 0.382 ± 0.018	3.616AspAsp: 3.616 ± 0.059	3.829AspGlu: 3.829 ± 0.073	1.643AspPhe: 1.643 ± 0.037	5.786AspGly: 5.786 ± 0.077	1.177AspHis: 1.177 ± 0.03	2.166AspIle: 2.166 ± 0.041	0.878AspLys: 0.878 ± 0.027	6.191AspLeu: 6.191 ± 0.083	0.709AspMet: 0.709 ± 0.026	1.04AspAsn: 1.04 ± 0.034	4.108AspPro: 4.108 ± 0.08	1.755AspGln: 1.755 ± 0.036	4.075AspArg: 4.075 ± 0.068	3.247AspSer: 3.247 ± 0.049	2.851AspThr: 2.851 ± 0.061	5.04AspVal: 5.04 ± 0.063	0.866AspTrp: 0.866 ± 0.03	1.209AspTyr: 1.209 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.022GluAla: 6.022 ± 0.093	0.321GluCys: 0.321 ± 0.015	2.045GluAsp: 2.045 ± 0.039	2.437GluGlu: 2.437 ± 0.053	1.629GluPhe: 1.629 ± 0.037	3.037GluGly: 3.037 ± 0.058	1.291GluHis: 1.291 ± 0.033	2.658GluIle: 2.658 ± 0.054	1.225GluLys: 1.225 ± 0.034	6.603GluLeu: 6.603 ± 0.1	0.91GluMet: 0.91 ± 0.029	1.045GluAsn: 1.045 ± 0.027	2.846GluPro: 2.846 ± 0.055	2.307GluGln: 2.307 ± 0.055	4.219GluArg: 4.219 ± 0.073	2.994GluSer: 2.994 ± 0.053	2.711GluThr: 2.711 ± 0.047	4.43GluVal: 4.43 ± 0.069	0.709GluTrp: 0.709 ± 0.021	1.006GluTyr: 1.006 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.026PheAla: 4.026 ± 0.057	0.301PheCys: 0.301 ± 0.016	2.202PheAsp: 2.202 ± 0.033	1.412PheGlu: 1.412 ± 0.033	0.936PhePhe: 0.936 ± 0.03	3.326PheGly: 3.326 ± 0.049	0.558PheHis: 0.558 ± 0.018	1.143PheIle: 1.143 ± 0.028	0.506PheLys: 0.506 ± 0.02	2.497PheLeu: 2.497 ± 0.049	0.41PheMet: 0.41 ± 0.018	0.757PheAsn: 0.757 ± 0.025	1.222PhePro: 1.222 ± 0.032	0.688PheGln: 0.688 ± 0.025	1.595PheArg: 1.595 ± 0.031	1.826PheSer: 1.826 ± 0.039	2.107PheThr: 2.107 ± 0.047	2.569PheVal: 2.569 ± 0.047	0.408PheTrp: 0.408 ± 0.02	0.683PheTyr: 0.683 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	10.366GlyAla: 10.366 ± 0.164	0.779GlyCys: 0.779 ± 0.026	4.823GlyAsp: 4.823 ± 0.067	4.364GlyGlu: 4.364 ± 0.056	2.959GlyPhe: 2.959 ± 0.05	8.065GlyGly: 8.065 ± 0.162	1.917GlyHis: 1.917 ± 0.051	3.935GlyIle: 3.935 ± 0.055	2.19GlyLys: 2.19 ± 0.049	8.808GlyLeu: 8.808 ± 0.092	1.77GlyMet: 1.77 ± 0.038	1.967GlyAsn: 1.967 ± 0.058	4.133GlyPro: 4.133 ± 0.061	2.835GlyGln: 2.835 ± 0.049	6.113GlyArg: 6.113 ± 0.082	6.261GlySer: 6.261 ± 0.123	5.481GlyThr: 5.481 ± 0.092	7.819GlyVal: 7.819 ± 0.087	1.636GlyTrp: 1.636 ± 0.043	2.284GlyTyr: 2.284 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.212HisAla: 2.212 ± 0.044	0.182HisCys: 0.182 ± 0.012	1.306HisAsp: 1.306 ± 0.033	1.046HisGlu: 1.046 ± 0.027	0.647HisPhe: 0.647 ± 0.021	1.943HisGly: 1.943 ± 0.041	0.585HisHis: 0.585 ± 0.021	0.793HisIle: 0.793 ± 0.023	0.267HisLys: 0.267 ± 0.014	2.159HisLeu: 2.159 ± 0.043	0.281HisMet: 0.281 ± 0.015	0.467HisAsn: 0.467 ± 0.018	1.508HisPro: 1.508 ± 0.039	0.653HisGln: 0.653 ± 0.023	1.678HisArg: 1.678 ± 0.044	1.218HisSer: 1.218 ± 0.028	1.057HisThr: 1.057 ± 0.039	1.527HisVal: 1.527 ± 0.033	0.319HisTrp: 0.319 ± 0.016	0.48HisTyr: 0.48 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.329IleAla: 6.329 ± 0.083	0.414IleCys: 0.414 ± 0.02	3.195IleAsp: 3.195 ± 0.044	2.573IleGlu: 2.573 ± 0.05	1.224IlePhe: 1.224 ± 0.034	4.482IleGly: 4.482 ± 0.061	0.756IleHis: 0.756 ± 0.024	1.528IleIle: 1.528 ± 0.039	0.801IleLys: 0.801 ± 0.025	3.254IleLeu: 3.254 ± 0.055	0.529IleMet: 0.529 ± 0.02	1.166IleAsn: 1.166 ± 0.04	2.224IlePro: 2.224 ± 0.038	1.037IleGln: 1.037 ± 0.03	2.636IleArg: 2.636 ± 0.048	3.015IleSer: 3.015 ± 0.054	3.009IleThr: 3.009 ± 0.061	3.895IleVal: 3.895 ± 0.054	0.499IleTrp: 0.499 ± 0.02	0.826IleTyr: 0.826 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.682LysAla: 2.682 ± 0.059	0.099LysCys: 0.099 ± 0.009	0.913LysAsp: 0.913 ± 0.027	0.781LysGlu: 0.781 ± 0.029	0.593LysPhe: 0.593 ± 0.021	1.462LysGly: 1.462 ± 0.036	0.49LysHis: 0.49 ± 0.017	0.932LysIle: 0.932 ± 0.031	0.665LysLys: 0.665 ± 0.042	2.112LysLeu: 2.112 ± 0.039	0.408LysMet: 0.408 ± 0.018	0.491LysAsn: 0.491 ± 0.02	1.343LysPro: 1.343 ± 0.035	0.713LysGln: 0.713 ± 0.023	1.474LysArg: 1.474 ± 0.032	1.469LysSer: 1.469 ± 0.035	1.423LysThr: 1.423 ± 0.035	1.861LysVal: 1.861 ± 0.044	0.269LysTrp: 0.269 ± 0.015	0.508LysTyr: 0.508 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.382LeuAla: 14.382 ± 0.115	0.734LeuCys: 0.734 ± 0.023	6.297LeuAsp: 6.297 ± 0.086	4.421LeuGlu: 4.421 ± 0.068	2.638LeuPhe: 2.638 ± 0.05	8.707LeuGly: 8.707 ± 0.086	2.033LeuHis: 2.033 ± 0.048	4.656LeuIle: 4.656 ± 0.075	1.846LeuLys: 1.846 ± 0.044	10.816LeuLeu: 10.816 ± 0.14	1.612LeuMet: 1.612 ± 0.034	2.328LeuAsn: 2.328 ± 0.049	5.861LeuPro: 5.861 ± 0.07	2.989LeuGln: 2.989 ± 0.049	7.668LeuArg: 7.668 ± 0.115	6.278LeuSer: 6.278 ± 0.08	6.631LeuThr: 6.631 ± 0.088	8.704LeuVal: 8.704 ± 0.09	1.118LeuTrp: 1.118 ± 0.032	1.703LeuTyr: 1.703 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.01MetAla: 2.01 ± 0.041	0.133MetCys: 0.133 ± 0.01	0.724MetAsp: 0.724 ± 0.022	0.599MetGlu: 0.599 ± 0.022	0.486MetPhe: 0.486 ± 0.021	1.178MetGly: 1.178 ± 0.027	0.339MetHis: 0.339 ± 0.016	0.814MetIle: 0.814 ± 0.028	0.402MetLys: 0.402 ± 0.016	1.87MetLeu: 1.87 ± 0.039	0.31MetMet: 0.31 ± 0.017	0.49MetAsn: 0.49 ± 0.019	1.067MetPro: 1.067 ± 0.029	0.539MetGln: 0.539 ± 0.02	1.278MetArg: 1.278 ± 0.03	1.498MetSer: 1.498 ± 0.037	1.697MetThr: 1.697 ± 0.034	1.3MetVal: 1.3 ± 0.034	0.183MetTrp: 0.183 ± 0.012	0.282MetTyr: 0.282 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.88AsnAla: 2.88 ± 0.062	0.198AsnCys: 0.198 ± 0.013	1.362AsnAsp: 1.362 ± 0.038	1.03AsnGlu: 1.03 ± 0.03	0.675AsnPhe: 0.675 ± 0.023	2.297AsnGly: 2.297 ± 0.054	0.451AsnHis: 0.451 ± 0.018	0.941AsnIle: 0.941 ± 0.033	0.458AsnLys: 0.458 ± 0.017	2.255AsnLeu: 2.255 ± 0.059	0.339AsnMet: 0.339 ± 0.015	0.607AsnAsn: 0.607 ± 0.029	1.757AsnPro: 1.757 ± 0.043	0.731AsnGln: 0.731 ± 0.025	1.452AsnArg: 1.452 ± 0.029	1.465AsnSer: 1.465 ± 0.046	1.426AsnThr: 1.426 ± 0.058	1.963AsnVal: 1.963 ± 0.057	0.375AsnTrp: 0.375 ± 0.017	0.542AsnTyr: 0.542 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	7.717ProAla: 7.717 ± 0.098	0.281ProCys: 0.281 ± 0.015	3.677ProAsp: 3.677 ± 0.075	3.207ProGlu: 3.207 ± 0.059	1.481ProPhe: 1.481 ± 0.037	5.174ProGly: 5.174 ± 0.07	1.066ProHis: 1.066 ± 0.031	2.318ProIle: 2.318 ± 0.044	1.324ProLys: 1.324 ± 0.035	4.851ProLeu: 4.851 ± 0.075	0.976ProMet: 0.976 ± 0.025	1.388ProAsn: 1.388 ± 0.032	3.227ProPro: 3.227 ± 0.083	1.843ProGln: 1.843 ± 0.043	3.128ProArg: 3.128 ± 0.058	3.731ProSer: 3.731 ± 0.068	4.33ProThr: 4.33 ± 0.105	4.841ProVal: 4.841 ± 0.07	0.741ProTrp: 0.741 ± 0.026	1.051ProTyr: 1.051 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.991GlnAla: 3.991 ± 0.056	0.178GlnCys: 0.178 ± 0.012	1.16GlnAsp: 1.16 ± 0.028	1.144GlnGlu: 1.144 ± 0.032	0.942GlnPhe: 0.942 ± 0.029	1.985GlnGly: 1.985 ± 0.036	0.745GlnHis: 0.745 ± 0.023	1.61GlnIle: 1.61 ± 0.033	0.602GlnLys: 0.602 ± 0.021	4.048GlnLeu: 4.048 ± 0.064	0.614GlnMet: 0.614 ± 0.02	0.718GlnAsn: 0.718 ± 0.023	1.956GlnPro: 1.956 ± 0.047	1.469GlnGln: 1.469 ± 0.039	2.825GlnArg: 2.825 ± 0.058	1.911GlnSer: 1.911 ± 0.036	1.986GlnThr: 1.986 ± 0.04	2.733GlnVal: 2.733 ± 0.047	0.504GlnTrp: 0.504 ± 0.018	0.655GlnTyr: 0.655 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.1ArgAla: 8.1 ± 0.106	0.484ArgCys: 0.484 ± 0.019	3.8ArgAsp: 3.8 ± 0.065	3.689ArgGlu: 3.689 ± 0.069	2.216ArgPhe: 2.216 ± 0.042	4.922ArgGly: 4.922 ± 0.073	1.592ArgHis: 1.592 ± 0.041	3.217ArgIle: 3.217 ± 0.054	1.311ArgLys: 1.311 ± 0.037	7.373ArgLeu: 7.373 ± 0.099	1.512ArgMet: 1.512 ± 0.04	1.508ArgAsn: 1.508 ± 0.031	3.919ArgPro: 3.919 ± 0.075	2.259ArgGln: 2.259 ± 0.049	6.687ArgArg: 6.687 ± 0.1	4.663ArgSer: 4.663 ± 0.061	3.916ArgThr: 3.916 ± 0.077	5.436ArgVal: 5.436 ± 0.078	1.235ArgTrp: 1.235 ± 0.032	1.642ArgTyr: 1.642 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	8.709SerAla: 8.709 ± 0.152	0.475SerCys: 0.475 ± 0.023	3.697SerAsp: 3.697 ± 0.054	2.991SerGlu: 2.991 ± 0.06	1.903SerPhe: 1.903 ± 0.039	6.644SerGly: 6.644 ± 0.11	1.168SerHis: 1.168 ± 0.028	2.74SerIle: 2.74 ± 0.058	1.287SerLys: 1.287 ± 0.032	5.837SerLeu: 5.837 ± 0.072	1.368SerMet: 1.368 ± 0.033	1.481SerAsn: 1.481 ± 0.045	3.539SerPro: 3.539 ± 0.061	1.815SerGln: 1.815 ± 0.034	3.981SerArg: 3.981 ± 0.06	4.601SerSer: 4.601 ± 0.098	4.489SerThr: 4.489 ± 0.117	5.564SerVal: 5.564 ± 0.089	0.982SerTrp: 0.982 ± 0.025	1.493SerTyr: 1.493 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	8.694ThrAla: 8.694 ± 0.169	0.445ThrCys: 0.445 ± 0.03	3.682ThrAsp: 3.682 ± 0.063	2.931ThrGlu: 2.931 ± 0.046	1.993ThrPhe: 1.993 ± 0.047	6.23ThrGly: 6.23 ± 0.111	1.228ThrHis: 1.228 ± 0.038	2.854ThrIle: 2.854 ± 0.069	1.376ThrLys: 1.376 ± 0.034	6.236ThrLeu: 6.236 ± 0.076	1.081ThrMet: 1.081 ± 0.027	1.614ThrAsn: 1.614 ± 0.052	4.481ThrPro: 4.481 ± 0.098	1.822ThrGln: 1.822 ± 0.044	3.537ThrArg: 3.537 ± 0.062	4.428ThrSer: 4.428 ± 0.099	4.613ThrThr: 4.613 ± 0.14	5.81ThrVal: 5.81 ± 0.117	0.83ThrTrp: 0.83 ± 0.029	1.354ThrTyr: 1.354 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	11.734ValAla: 11.734 ± 0.128	0.693ValCys: 0.693 ± 0.027	5.121ValAsp: 5.121 ± 0.056	4.562ValGlu: 4.562 ± 0.077	2.297ValPhe: 2.297 ± 0.038	7.242ValGly: 7.242 ± 0.097	1.653ValHis: 1.653 ± 0.037	3.929ValIle: 3.929 ± 0.06	1.686ValLys: 1.686 ± 0.035	8.901ValLeu: 8.901 ± 0.096	1.315ValMet: 1.315 ± 0.033	2.195ValAsn: 2.195 ± 0.049	4.55ValPro: 4.55 ± 0.088	2.456ValGln: 2.456 ± 0.045	5.414ValArg: 5.414 ± 0.074	5.507ValSer: 5.507 ± 0.081	6.121ValThr: 6.121 ± 0.14	8.218ValVal: 8.218 ± 0.085	1.002ValTrp: 1.002 ± 0.023	1.504ValTyr: 1.504 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.376TrpAla: 1.376 ± 0.032	0.136TrpCys: 0.136 ± 0.01	0.67TrpAsp: 0.67 ± 0.024	0.551TrpGlu: 0.551 ± 0.021	0.478TrpPhe: 0.478 ± 0.017	1.003TrpGly: 1.003 ± 0.028	0.337TrpHis: 0.337 ± 0.015	0.69TrpIle: 0.69 ± 0.023	0.263TrpLys: 0.263 ± 0.013	1.705TrpLeu: 1.705 ± 0.035	0.285TrpMet: 0.285 ± 0.016	0.352TrpAsn: 0.352 ± 0.016	0.748TrpPro: 0.748 ± 0.025	0.582TrpGln: 0.582 ± 0.024	1.19TrpArg: 1.19 ± 0.032	1.119TrpSer: 1.119 ± 0.035	0.872TrpThr: 0.872 ± 0.029	0.973TrpVal: 0.973 ± 0.028	0.311TrpTrp: 0.311 ± 0.018	0.297TrpTyr: 0.297 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.373TyrAla: 2.373 ± 0.044	0.193TyrCys: 0.193 ± 0.011	1.287TyrAsp: 1.287 ± 0.041	0.984TyrGlu: 0.984 ± 0.026	0.752TyrPhe: 0.752 ± 0.025	2.008TyrGly: 2.008 ± 0.043	0.36TyrHis: 0.36 ± 0.018	0.677TyrIle: 0.677 ± 0.022	0.363TyrLys: 0.363 ± 0.019	2.33TyrLeu: 2.33 ± 0.042	0.23TyrMet: 0.23 ± 0.012	0.487TyrAsn: 0.487 ± 0.02	1.126TyrPro: 1.126 ± 0.03	0.731TyrGln: 0.731 ± 0.021	1.622TyrArg: 1.622 ± 0.032	1.275TyrSer: 1.275 ± 0.031	1.229TyrThr: 1.229 ± 0.037	1.623TyrVal: 1.623 ± 0.033	0.33TyrTrp: 0.33 ± 0.016	0.48TyrTyr: 0.48 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4295 proteins (1461866 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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