Amino acid dipepetide frequency for Rhizophagus irregularis (strain DAOM 197198w) (Glomus intraradices)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.021AlaAla: 3.021 ± 0.033
0.657AlaCys: 0.657 ± 0.009
2.292AlaAsp: 2.292 ± 0.017
2.97AlaGlu: 2.97 ± 0.029
2.394AlaPhe: 2.394 ± 0.027
1.853AlaGly: 1.853 ± 0.016
0.988AlaHis: 0.988 ± 0.011
3.861AlaIle: 3.861 ± 0.022
3.46AlaLys: 3.46 ± 0.023
4.172AlaLeu: 4.172 ± 0.027
1.041AlaMet: 1.041 ± 0.019
2.759AlaAsn: 2.759 ± 0.02
1.751AlaPro: 1.751 ± 0.02
1.79AlaGln: 1.79 ± 0.022
1.883AlaArg: 1.883 ± 0.016
3.344AlaSer: 3.344 ± 0.019
2.495AlaThr: 2.495 ± 0.019
2.235AlaVal: 2.235 ± 0.016
0.424AlaTrp: 0.424 ± 0.007
1.546AlaTyr: 1.546 ± 0.015
0.0AlaXaa: 0.0 ± 0.0
Cys
0.597CysAla: 0.597 ± 0.008
0.277CysCys: 0.277 ± 0.006
0.897CysAsp: 0.897 ± 0.01
0.983CysGlu: 0.983 ± 0.01
0.68CysPhe: 0.68 ± 0.008
0.954CysGly: 0.954 ± 0.011
0.369CysHis: 0.369 ± 0.007
1.091CysIle: 1.091 ± 0.012
1.306CysLys: 1.306 ± 0.014
1.527CysLeu: 1.527 ± 0.013
0.264CysMet: 0.264 ± 0.005
1.123CysAsn: 1.123 ± 0.014
0.619CysPro: 0.619 ± 0.01
0.685CysGln: 0.685 ± 0.009
0.675CysArg: 0.675 ± 0.009
1.045CysSer: 1.045 ± 0.01
0.668CysThr: 0.668 ± 0.009
0.652CysVal: 0.652 ± 0.008
0.352CysTrp: 0.352 ± 0.006
1.092CysTyr: 1.092 ± 0.021
0.0CysXaa: 0.0 ± 0.0
Asp
2.318AspAla: 2.318 ± 0.019
0.767AspCys: 0.767 ± 0.009
4.834AspAsp: 4.834 ± 0.037
4.691AspGlu: 4.691 ± 0.028
2.972AspPhe: 2.972 ± 0.019
2.746AspGly: 2.746 ± 0.02
1.132AspHis: 1.132 ± 0.013
5.136AspIle: 5.136 ± 0.026
4.333AspLys: 4.333 ± 0.027
5.229AspLeu: 5.229 ± 0.024
1.127AspMet: 1.127 ± 0.011
4.202AspAsn: 4.202 ± 0.021
2.274AspPro: 2.274 ± 0.017
1.738AspGln: 1.738 ± 0.016
2.015AspArg: 2.015 ± 0.034
4.051AspSer: 4.051 ± 0.026
2.66AspThr: 2.66 ± 0.017
2.838AspVal: 2.838 ± 0.019
0.691AspTrp: 0.691 ± 0.009
2.613AspTyr: 2.613 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
2.924GluAla: 2.924 ± 0.023
0.972GluCys: 0.972 ± 0.01
3.781GluAsp: 3.781 ± 0.023
5.96GluGlu: 5.96 ± 0.042
3.284GluPhe: 3.284 ± 0.022
2.535GluGly: 2.535 ± 0.023
1.232GluHis: 1.232 ± 0.011
6.586GluIle: 6.586 ± 0.032
6.632GluLys: 6.632 ± 0.047
6.567GluLeu: 6.567 ± 0.033
1.434GluMet: 1.434 ± 0.012
5.61GluAsn: 5.61 ± 0.034
1.85GluPro: 1.85 ± 0.018
2.385GluGln: 2.385 ± 0.015
3.025GluArg: 3.025 ± 0.032
4.394GluSer: 4.394 ± 0.023
3.202GluThr: 3.202 ± 0.022
3.53GluVal: 3.53 ± 0.023
1.157GluTrp: 1.157 ± 0.014
2.909GluTyr: 2.909 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
1.959PheAla: 1.959 ± 0.016
0.794PheCys: 0.794 ± 0.009
2.678PheAsp: 2.678 ± 0.021
3.247PheGlu: 3.247 ± 0.025
1.954PhePhe: 1.954 ± 0.017
2.597PheGly: 2.597 ± 0.021
1.253PheHis: 1.253 ± 0.012
3.882PheIle: 3.882 ± 0.026
3.326PheLys: 3.326 ± 0.019
3.948PheLeu: 3.948 ± 0.023
0.918PheMet: 0.918 ± 0.01
3.339PheAsn: 3.339 ± 0.019
1.589PhePro: 1.589 ± 0.015
1.708PheGln: 1.708 ± 0.014
1.772PheArg: 1.772 ± 0.012
3.755PheSer: 3.755 ± 0.025
2.46PheThr: 2.46 ± 0.018
2.202PheVal: 2.202 ± 0.017
0.503PheTrp: 0.503 ± 0.009
2.14PheTyr: 2.14 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
1.745GlyAla: 1.745 ± 0.019
0.718GlyCys: 0.718 ± 0.01
2.253GlyAsp: 2.253 ± 0.017
2.659GlyGlu: 2.659 ± 0.02
2.17GlyPhe: 2.17 ± 0.018
2.767GlyGly: 2.767 ± 0.026
1.049GlyHis: 1.049 ± 0.014
4.185GlyIle: 4.185 ± 0.033
3.564GlyLys: 3.564 ± 0.022
3.753GlyLeu: 3.753 ± 0.023
0.912GlyMet: 0.912 ± 0.011
3.295GlyAsn: 3.295 ± 0.026
1.512GlyPro: 1.512 ± 0.016
1.44GlyGln: 1.44 ± 0.015
2.009GlyArg: 2.009 ± 0.015
3.118GlySer: 3.118 ± 0.021
2.676GlyThr: 2.676 ± 0.024
2.439GlyVal: 2.439 ± 0.018
0.545GlyTrp: 0.545 ± 0.007
2.052GlyTyr: 2.052 ± 0.02
0.0GlyXaa: 0.0 ± 0.0
His
0.917HisAla: 0.917 ± 0.011
0.383HisCys: 0.383 ± 0.006
1.291HisAsp: 1.291 ± 0.012
1.313HisGlu: 1.313 ± 0.011
1.039HisPhe: 1.039 ± 0.011
0.964HisGly: 0.964 ± 0.011
0.706HisHis: 0.706 ± 0.012
1.663HisIle: 1.663 ± 0.013
1.448HisLys: 1.448 ± 0.014
2.064HisLeu: 2.064 ± 0.014
0.406HisMet: 0.406 ± 0.007
1.537HisAsn: 1.537 ± 0.016
0.998HisPro: 0.998 ± 0.011
0.96HisGln: 0.96 ± 0.01
0.991HisArg: 0.991 ± 0.009
1.678HisSer: 1.678 ± 0.013
1.02HisThr: 1.02 ± 0.011
1.11HisVal: 1.11 ± 0.012
0.302HisTrp: 0.302 ± 0.008
0.932HisTyr: 0.932 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
3.428IleAla: 3.428 ± 0.024
1.422IleCys: 1.422 ± 0.014
4.953IleAsp: 4.953 ± 0.023
5.44IleGlu: 5.44 ± 0.032
3.644IlePhe: 3.644 ± 0.022
3.435IleGly: 3.435 ± 0.024
1.832IleHis: 1.832 ± 0.014
6.824IleIle: 6.824 ± 0.037
6.485IleLys: 6.485 ± 0.036
7.468IleLeu: 7.468 ± 0.036
1.646IleMet: 1.646 ± 0.012
5.765IleAsn: 5.765 ± 0.03
3.76IlePro: 3.76 ± 0.021
3.053IleGln: 3.053 ± 0.018
3.282IleArg: 3.282 ± 0.021
6.523IleSer: 6.523 ± 0.03
4.417IleThr: 4.417 ± 0.025
3.805IleVal: 3.805 ± 0.02
0.944IleTrp: 0.944 ± 0.011
3.567IleTyr: 3.567 ± 0.023
0.0IleXaa: 0.0 ± 0.0
Lys
4.179LysAla: 4.179 ± 0.047
1.401LysCys: 1.401 ± 0.014
4.714LysAsp: 4.714 ± 0.035
6.354LysGlu: 6.354 ± 0.036
3.571LysPhe: 3.571 ± 0.024
3.121LysGly: 3.121 ± 0.025
1.484LysHis: 1.484 ± 0.014
6.497LysIle: 6.497 ± 0.032
7.338LysLys: 7.338 ± 0.042
7.11LysLeu: 7.11 ± 0.036
1.515LysMet: 1.515 ± 0.014
6.152LysAsn: 6.152 ± 0.034
2.505LysPro: 2.505 ± 0.016
2.799LysGln: 2.799 ± 0.019
3.932LysArg: 3.932 ± 0.024
5.761LysSer: 5.761 ± 0.029
3.474LysThr: 3.474 ± 0.022
3.865LysVal: 3.865 ± 0.023
1.073LysTrp: 1.073 ± 0.011
3.467LysTyr: 3.467 ± 0.025
0.0LysXaa: 0.0 ± 0.0
Leu
4.587LeuAla: 4.587 ± 0.028
1.463LeuCys: 1.463 ± 0.014
4.803LeuAsp: 4.803 ± 0.023
6.365LeuGlu: 6.365 ± 0.035
3.91LeuPhe: 3.91 ± 0.025
4.003LeuGly: 4.003 ± 0.03
2.104LeuHis: 2.104 ± 0.018
6.693LeuIle: 6.693 ± 0.033
7.681LeuLys: 7.681 ± 0.037
8.092LeuLeu: 8.092 ± 0.038
1.751LeuMet: 1.751 ± 0.013
6.061LeuAsn: 6.061 ± 0.025
3.977LeuPro: 3.977 ± 0.023
3.791LeuGln: 3.791 ± 0.025
4.273LeuArg: 4.273 ± 0.023
7.21LeuSer: 7.21 ± 0.029
4.53LeuThr: 4.53 ± 0.024
4.176LeuVal: 4.176 ± 0.021
1.072LeuTrp: 1.072 ± 0.011
3.563LeuTyr: 3.563 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
1.127MetAla: 1.127 ± 0.012
0.242MetCys: 0.242 ± 0.005
1.212MetAsp: 1.212 ± 0.011
1.476MetGlu: 1.476 ± 0.016
0.844MetPhe: 0.844 ± 0.014
0.801MetGly: 0.801 ± 0.01
0.352MetHis: 0.352 ± 0.008
1.526MetIle: 1.526 ± 0.014
1.615MetLys: 1.615 ± 0.014
1.571MetLeu: 1.571 ± 0.013
0.498MetMet: 0.498 ± 0.008
1.409MetAsn: 1.409 ± 0.012
0.678MetPro: 0.678 ± 0.009
0.724MetGln: 0.724 ± 0.01
0.779MetArg: 0.779 ± 0.009
1.69MetSer: 1.69 ± 0.013
1.053MetThr: 1.053 ± 0.011
1.056MetVal: 1.056 ± 0.011
0.24MetTrp: 0.24 ± 0.004
0.683MetTyr: 0.683 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
2.683AsnAla: 2.683 ± 0.02
1.062AsnCys: 1.062 ± 0.01
4.547AsnAsp: 4.547 ± 0.025
5.309AsnGlu: 5.309 ± 0.031
3.428AsnPhe: 3.428 ± 0.02
3.488AsnGly: 3.488 ± 0.035
1.492AsnHis: 1.492 ± 0.014
6.437AsnIle: 6.437 ± 0.03
5.471AsnLys: 5.471 ± 0.028
6.874AsnLeu: 6.874 ± 0.041
1.355AsnMet: 1.355 ± 0.013
6.996AsnAsn: 6.996 ± 0.046
2.704AsnPro: 2.704 ± 0.019
2.574AsnGln: 2.574 ± 0.02
2.583AsnArg: 2.583 ± 0.02
5.664AsnSer: 5.664 ± 0.03
3.512AsnThr: 3.512 ± 0.021
3.41AsnVal: 3.41 ± 0.021
1.027AsnTrp: 1.027 ± 0.016
3.17AsnTyr: 3.17 ± 0.021
0.0AsnXaa: 0.0 ± 0.0
Pro
1.667ProAla: 1.667 ± 0.015
0.47ProCys: 0.47 ± 0.009
2.165ProAsp: 2.165 ± 0.017
2.806ProGlu: 2.806 ± 0.02
1.893ProPhe: 1.893 ± 0.015
1.547ProGly: 1.547 ± 0.017
0.787ProHis: 0.787 ± 0.01
3.019ProIle: 3.019 ± 0.018
2.917ProLys: 2.917 ± 0.024
3.345ProLeu: 3.345 ± 0.021
0.603ProMet: 0.603 ± 0.009
2.81ProAsn: 2.81 ± 0.018
2.529ProPro: 2.529 ± 0.037
1.537ProGln: 1.537 ± 0.019
1.496ProArg: 1.496 ± 0.015
3.594ProSer: 3.594 ± 0.021
2.512ProThr: 2.512 ± 0.02
1.902ProVal: 1.902 ± 0.016
0.343ProTrp: 0.343 ± 0.007
1.852ProTyr: 1.852 ± 0.016
0.0ProXaa: 0.0 ± 0.0
Gln
1.612GlnAla: 1.612 ± 0.013
0.567GlnCys: 0.567 ± 0.009
1.971GlnAsp: 1.971 ± 0.017
2.701GlnGlu: 2.701 ± 0.019
1.67GlnPhe: 1.67 ± 0.015
1.363GlnGly: 1.363 ± 0.015
0.982GlnHis: 0.982 ± 0.011
2.966GlnIle: 2.966 ± 0.019
3.241GlnLys: 3.241 ± 0.026
3.511GlnLeu: 3.511 ± 0.021
0.791GlnMet: 0.791 ± 0.01
3.235GlnAsn: 3.235 ± 0.026
1.476GlnPro: 1.476 ± 0.02
2.447GlnGln: 2.447 ± 0.035
1.691GlnArg: 1.691 ± 0.014
2.601GlnSer: 2.601 ± 0.019
1.841GlnThr: 1.841 ± 0.015
1.753GlnVal: 1.753 ± 0.015
0.369GlnTrp: 0.369 ± 0.006
1.525GlnTyr: 1.525 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
1.951ArgAla: 1.951 ± 0.016
0.679ArgCys: 0.679 ± 0.009
2.485ArgAsp: 2.485 ± 0.038
2.822ArgGlu: 2.822 ± 0.028
1.92ArgPhe: 1.92 ± 0.016
1.863ArgGly: 1.863 ± 0.016
0.949ArgHis: 0.949 ± 0.011
3.23ArgIle: 3.23 ± 0.021
3.696ArgLys: 3.696 ± 0.022
3.75ArgLeu: 3.75 ± 0.023
0.846ArgMet: 0.846 ± 0.008
2.968ArgAsn: 2.968 ± 0.016
1.938ArgPro: 1.938 ± 0.016
1.675ArgGln: 1.675 ± 0.016
2.497ArgArg: 2.497 ± 0.021
3.123ArgSer: 3.123 ± 0.021
2.02ArgThr: 2.02 ± 0.016
2.024ArgVal: 2.024 ± 0.017
0.519ArgTrp: 0.519 ± 0.007
1.663ArgTyr: 1.663 ± 0.014
0.0ArgXaa: 0.0 ± 0.0
Ser
3.366SerAla: 3.366 ± 0.022
1.085SerCys: 1.085 ± 0.012
4.488SerAsp: 4.488 ± 0.022
4.668SerGlu: 4.668 ± 0.025
3.725SerPhe: 3.725 ± 0.022
3.573SerGly: 3.573 ± 0.02
1.663SerHis: 1.663 ± 0.014
5.772SerIle: 5.772 ± 0.026
5.76SerLys: 5.76 ± 0.028
7.153SerLeu: 7.153 ± 0.033
1.353SerMet: 1.353 ± 0.013
5.661SerAsn: 5.661 ± 0.03
3.359SerPro: 3.359 ± 0.028
3.273SerGln: 3.273 ± 0.022
3.331SerArg: 3.331 ± 0.022
8.093SerSer: 8.093 ± 0.046
4.578SerThr: 4.578 ± 0.03
3.316SerVal: 3.316 ± 0.02
0.806SerTrp: 0.806 ± 0.01
2.809SerTyr: 2.809 ± 0.021
0.0SerXaa: 0.0 ± 0.0
Thr
2.325ThrAla: 2.325 ± 0.02
0.773ThrCys: 0.773 ± 0.009
2.668ThrAsp: 2.668 ± 0.02
3.196ThrGlu: 3.196 ± 0.024
2.343ThrPhe: 2.343 ± 0.019
2.342ThrGly: 2.342 ± 0.02
1.069ThrHis: 1.069 ± 0.011
4.059ThrIle: 4.059 ± 0.022
4.044ThrLys: 4.044 ± 0.021
4.754ThrLeu: 4.754 ± 0.023
0.914ThrMet: 0.914 ± 0.01
3.509ThrAsn: 3.509 ± 0.023
2.636ThrPro: 2.636 ± 0.022
1.874ThrGln: 1.874 ± 0.019
2.149ThrArg: 2.149 ± 0.017
4.975ThrSer: 4.975 ± 0.03
3.391ThrThr: 3.391 ± 0.027
2.486ThrVal: 2.486 ± 0.019
0.62ThrTrp: 0.62 ± 0.008
1.784ThrTyr: 1.784 ± 0.014
0.0ThrXaa: 0.0 ± 0.0
Val
2.51ValAla: 2.51 ± 0.019
0.728ValCys: 0.728 ± 0.009
2.921ValAsp: 2.921 ± 0.017
3.265ValGlu: 3.265 ± 0.02
2.055ValPhe: 2.055 ± 0.015
2.157ValGly: 2.157 ± 0.017
1.054ValHis: 1.054 ± 0.01
3.84ValIle: 3.84 ± 0.02
3.77ValLys: 3.77 ± 0.023
4.427ValLeu: 4.427 ± 0.023
1.061ValMet: 1.061 ± 0.01
3.181ValAsn: 3.181 ± 0.019
2.0ValPro: 2.0 ± 0.017
1.714ValGln: 1.714 ± 0.016
1.976ValArg: 1.976 ± 0.016
3.396ValSer: 3.396 ± 0.019
2.655ValThr: 2.655 ± 0.016
2.645ValVal: 2.645 ± 0.019
0.519ValTrp: 0.519 ± 0.008
1.915ValTyr: 1.915 ± 0.014
0.0ValXaa: 0.0 ± 0.0
Trp
0.481TrpAla: 0.481 ± 0.007
0.389TrpCys: 0.389 ± 0.007
0.829TrpAsp: 0.829 ± 0.011
0.83TrpGlu: 0.83 ± 0.009
0.506TrpPhe: 0.506 ± 0.008
0.464TrpGly: 0.464 ± 0.007
0.235TrpHis: 0.235 ± 0.004
1.294TrpIle: 1.294 ± 0.016
1.204TrpLys: 1.204 ± 0.012
0.851TrpLeu: 0.851 ± 0.01
0.292TrpMet: 0.292 ± 0.006
0.93TrpAsn: 0.93 ± 0.011
0.29TrpPro: 0.29 ± 0.005
0.348TrpGln: 0.348 ± 0.006
0.517TrpArg: 0.517 ± 0.007
0.761TrpSer: 0.761 ± 0.01
0.727TrpThr: 0.727 ± 0.01
0.554TrpVal: 0.554 ± 0.007
0.146TrpTrp: 0.146 ± 0.004
0.694TrpTyr: 0.694 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.542TyrAla: 1.542 ± 0.012
1.005TyrCys: 1.005 ± 0.012
2.585TyrAsp: 2.585 ± 0.018
2.913TyrGlu: 2.913 ± 0.023
2.018TyrPhe: 2.018 ± 0.017
2.288TyrGly: 2.288 ± 0.018
0.992TyrHis: 0.992 ± 0.01
3.132TyrIle: 3.132 ± 0.02
3.023TyrLys: 3.023 ± 0.021
3.939TyrLeu: 3.939 ± 0.022
0.848TyrMet: 0.848 ± 0.011
3.246TyrAsn: 3.246 ± 0.024
1.349TyrPro: 1.349 ± 0.014
1.8TyrGln: 1.8 ± 0.02
1.739TyrArg: 1.739 ± 0.014
3.053TyrSer: 3.053 ± 0.019
2.023TyrThr: 2.023 ± 0.014
1.792TyrVal: 1.792 ± 0.014
0.69TyrTrp: 0.69 ± 0.018
2.189TyrTyr: 2.189 ± 0.024
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.001XaaMet: 0.001 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.024XaaXaa: 0.024 ± 0.005
Statistics based on 28669 proteins (10097224 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski