Amino acid dipepetide frequency for Fusarium venenatum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.124AlaAla: 8.124 ± 0.063	1.111AlaCys: 1.111 ± 0.015	4.046AlaAsp: 4.046 ± 0.027	4.879AlaGlu: 4.879 ± 0.046	3.076AlaPhe: 3.076 ± 0.025	5.387AlaGly: 5.387 ± 0.034	1.661AlaHis: 1.661 ± 0.017	4.451AlaIle: 4.451 ± 0.026	4.134AlaLys: 4.134 ± 0.027	7.315AlaLeu: 7.315 ± 0.044	1.982AlaMet: 1.982 ± 0.02	2.924AlaAsn: 2.924 ± 0.022	4.584AlaPro: 4.584 ± 0.043	3.241AlaGln: 3.241 ± 0.025	4.433AlaArg: 4.433 ± 0.03	6.913AlaSer: 6.913 ± 0.041	5.159AlaThr: 5.159 ± 0.033	5.141AlaVal: 5.141 ± 0.034	1.16AlaTrp: 1.16 ± 0.017	2.107AlaTyr: 2.107 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.93CysAla: 0.93 ± 0.013	0.277CysCys: 0.277 ± 0.008	0.742CysAsp: 0.742 ± 0.012	0.642CysGlu: 0.642 ± 0.012	0.591CysPhe: 0.591 ± 0.01	0.981CysGly: 0.981 ± 0.016	0.352CysHis: 0.352 ± 0.008	0.785CysIle: 0.785 ± 0.011	0.587CysLys: 0.587 ± 0.011	1.294CysLeu: 1.294 ± 0.016	0.298CysMet: 0.298 ± 0.007	0.495CysAsn: 0.495 ± 0.01	0.69CysPro: 0.69 ± 0.013	0.509CysGln: 0.509 ± 0.01	0.773CysArg: 0.773 ± 0.011	0.96CysSer: 0.96 ± 0.013	0.767CysThr: 0.767 ± 0.012	0.853CysVal: 0.853 ± 0.015	0.226CysTrp: 0.226 ± 0.006	0.387CysTyr: 0.387 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.583AspAla: 4.583 ± 0.029	0.701AspCys: 0.701 ± 0.012	4.571AspAsp: 4.571 ± 0.039	4.617AspGlu: 4.617 ± 0.035	2.294AspPhe: 2.294 ± 0.019	4.089AspGly: 4.089 ± 0.033	1.276AspHis: 1.276 ± 0.016	3.297AspIle: 3.297 ± 0.028	2.795AspLys: 2.795 ± 0.024	5.039AspLeu: 5.039 ± 0.036	1.403AspMet: 1.403 ± 0.015	2.18AspAsn: 2.18 ± 0.019	3.233AspPro: 3.233 ± 0.022	1.994AspGln: 1.994 ± 0.018	2.981AspArg: 2.981 ± 0.03	4.276AspSer: 4.276 ± 0.028	3.154AspThr: 3.154 ± 0.026	3.732AspVal: 3.732 ± 0.022	0.94AspTrp: 0.94 ± 0.014	1.652AspTyr: 1.652 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.345GluAla: 5.345 ± 0.048	0.68GluCys: 0.68 ± 0.012	4.218GluAsp: 4.218 ± 0.034	5.312GluGlu: 5.312 ± 0.054	2.012GluPhe: 2.012 ± 0.019	3.634GluGly: 3.634 ± 0.028	1.402GluHis: 1.402 ± 0.017	3.085GluIle: 3.085 ± 0.022	3.741GluLys: 3.741 ± 0.036	5.098GluLeu: 5.098 ± 0.035	1.485GluMet: 1.485 ± 0.016	2.41GluAsn: 2.41 ± 0.02	2.976GluPro: 2.976 ± 0.036	2.463GluGln: 2.463 ± 0.023	3.663GluArg: 3.663 ± 0.033	4.404GluSer: 4.404 ± 0.035	3.83GluThr: 3.83 ± 0.032	3.553GluVal: 3.553 ± 0.023	0.916GluTrp: 0.916 ± 0.013	1.68GluTyr: 1.68 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	2.986PheAla: 2.986 ± 0.024	0.589PheCys: 0.589 ± 0.011	2.357PheAsp: 2.357 ± 0.023	2.203PheGlu: 2.203 ± 0.02	1.667PhePhe: 1.667 ± 0.018	2.894PheGly: 2.894 ± 0.025	0.911PheHis: 0.911 ± 0.013	1.988PheIle: 1.988 ± 0.018	1.672PheLys: 1.672 ± 0.017	3.419PheLeu: 3.419 ± 0.028	0.858PheMet: 0.858 ± 0.013	1.571PheAsn: 1.571 ± 0.017	1.884PhePro: 1.884 ± 0.018	1.432PheGln: 1.432 ± 0.015	1.871PheArg: 1.871 ± 0.017	3.032PheSer: 3.032 ± 0.027	2.234PheThr: 2.234 ± 0.02	2.441PheVal: 2.441 ± 0.02	0.679PheTrp: 0.679 ± 0.01	1.145PheTyr: 1.145 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.96GlyAla: 4.96 ± 0.039	0.923GlyCys: 0.923 ± 0.013	3.728GlyAsp: 3.728 ± 0.036	3.47GlyGlu: 3.47 ± 0.026	2.864GlyPhe: 2.864 ± 0.024	5.402GlyGly: 5.402 ± 0.052	1.685GlyHis: 1.685 ± 0.019	3.673GlyIle: 3.673 ± 0.031	3.452GlyLys: 3.452 ± 0.027	6.005GlyLeu: 6.005 ± 0.036	1.584GlyMet: 1.584 ± 0.018	2.704GlyAsn: 2.704 ± 0.027	3.221GlyPro: 3.221 ± 0.034	2.603GlyGln: 2.603 ± 0.024	3.902GlyArg: 3.902 ± 0.029	5.631GlySer: 5.631 ± 0.041	3.971GlyThr: 3.971 ± 0.042	4.212GlyVal: 4.212 ± 0.03	1.186GlyTrp: 1.186 ± 0.015	2.176GlyTyr: 2.176 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.698HisAla: 1.698 ± 0.017	0.348HisCys: 0.348 ± 0.009	1.416HisAsp: 1.416 ± 0.017	1.35HisGlu: 1.35 ± 0.016	0.92HisPhe: 0.92 ± 0.013	1.702HisGly: 1.702 ± 0.018	0.848HisHis: 0.848 ± 0.017	1.257HisIle: 1.257 ± 0.016	1.002HisLys: 1.002 ± 0.014	2.18HisLeu: 2.18 ± 0.02	0.521HisMet: 0.521 ± 0.01	0.916HisAsn: 0.916 ± 0.012	1.509HisPro: 1.509 ± 0.018	1.038HisGln: 1.038 ± 0.014	1.451HisArg: 1.451 ± 0.018	1.753HisSer: 1.753 ± 0.019	1.208HisThr: 1.208 ± 0.015	1.455HisVal: 1.455 ± 0.017	0.352HisTrp: 0.352 ± 0.008	0.722HisTyr: 0.722 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.28IleAla: 4.28 ± 0.031	0.807IleCys: 0.807 ± 0.012	3.059IleAsp: 3.059 ± 0.026	3.075IleGlu: 3.075 ± 0.025	2.086IlePhe: 2.086 ± 0.023	3.328IleGly: 3.328 ± 0.026	1.229IleHis: 1.229 ± 0.014	2.789IleIle: 2.789 ± 0.03	2.45IleLys: 2.45 ± 0.023	4.644IleLeu: 4.644 ± 0.036	1.127IleMet: 1.127 ± 0.013	2.016IleAsn: 2.016 ± 0.019	3.114IlePro: 3.114 ± 0.022	1.985IleGln: 1.985 ± 0.017	2.805IleArg: 2.805 ± 0.021	4.007IleSer: 4.007 ± 0.027	3.082IleThr: 3.082 ± 0.038	3.354IleVal: 3.354 ± 0.029	0.821IleTrp: 0.821 ± 0.012	1.468IleTyr: 1.468 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.332LysAla: 4.332 ± 0.031	0.568LysCys: 0.568 ± 0.01	3.137LysAsp: 3.137 ± 0.029	3.455LysGlu: 3.455 ± 0.032	1.559LysPhe: 1.559 ± 0.017	3.087LysGly: 3.087 ± 0.025	1.212LysHis: 1.212 ± 0.014	2.409LysIle: 2.409 ± 0.021	3.527LysLys: 3.527 ± 0.033	4.183LysLeu: 4.183 ± 0.028	1.088LysMet: 1.088 ± 0.013	1.966LysAsn: 1.966 ± 0.019	2.959LysPro: 2.959 ± 0.028	1.958LysGln: 1.958 ± 0.02	3.315LysArg: 3.315 ± 0.03	3.703LysSer: 3.703 ± 0.028	3.176LysThr: 3.176 ± 0.023	2.946LysVal: 2.946 ± 0.022	0.73LysTrp: 0.73 ± 0.011	1.459LysTyr: 1.459 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.437LeuAla: 7.437 ± 0.043	1.249LeuCys: 1.249 ± 0.015	5.154LeuAsp: 5.154 ± 0.033	5.417LeuGlu: 5.417 ± 0.041	3.316LeuPhe: 3.316 ± 0.029	5.781LeuGly: 5.781 ± 0.038	2.11LeuHis: 2.11 ± 0.02	4.127LeuIle: 4.127 ± 0.031	4.277LeuLys: 4.277 ± 0.029	7.995LeuLeu: 7.995 ± 0.056	1.858LeuMet: 1.858 ± 0.02	3.263LeuAsn: 3.263 ± 0.024	5.224LeuPro: 5.224 ± 0.034	3.673LeuGln: 3.673 ± 0.028	5.302LeuArg: 5.302 ± 0.035	7.115LeuSer: 7.115 ± 0.047	4.806LeuThr: 4.806 ± 0.028	5.455LeuVal: 5.455 ± 0.034	1.238LeuTrp: 1.238 ± 0.016	2.353LeuTyr: 2.353 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.295MetAla: 2.295 ± 0.018	0.265MetCys: 0.265 ± 0.006	1.317MetAsp: 1.317 ± 0.015	1.283MetGlu: 1.283 ± 0.016	0.799MetPhe: 0.799 ± 0.011	1.517MetGly: 1.517 ± 0.016	0.504MetHis: 0.504 ± 0.01	1.095MetIle: 1.095 ± 0.015	1.085MetLys: 1.085 ± 0.012	1.857MetLeu: 1.857 ± 0.018	0.641MetMet: 0.641 ± 0.012	0.856MetAsn: 0.856 ± 0.012	1.364MetPro: 1.364 ± 0.016	0.852MetGln: 0.852 ± 0.013	1.253MetArg: 1.253 ± 0.015	2.084MetSer: 2.084 ± 0.018	1.428MetThr: 1.428 ± 0.014	1.345MetVal: 1.345 ± 0.016	0.284MetTrp: 0.284 ± 0.007	0.549MetTyr: 0.549 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.08AsnAla: 3.08 ± 0.025	0.508AsnCys: 0.508 ± 0.009	2.267AsnAsp: 2.267 ± 0.021	2.172AsnGlu: 2.172 ± 0.019	1.449AsnPhe: 1.449 ± 0.015	3.063AsnGly: 3.063 ± 0.029	0.905AsnHis: 0.905 ± 0.013	2.21AsnIle: 2.21 ± 0.02	1.852AsnLys: 1.852 ± 0.019	3.347AsnLeu: 3.347 ± 0.026	0.964AsnMet: 0.964 ± 0.013	1.713AsnAsn: 1.713 ± 0.021	2.453AsnPro: 2.453 ± 0.021	1.427AsnGln: 1.427 ± 0.014	1.995AsnArg: 1.995 ± 0.019	2.946AsnSer: 2.946 ± 0.021	2.355AsnThr: 2.355 ± 0.02	2.406AsnVal: 2.406 ± 0.02	0.594AsnTrp: 0.594 ± 0.01	1.123AsnTyr: 1.123 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.774ProAla: 4.774 ± 0.042	0.567ProCys: 0.567 ± 0.012	3.249ProAsp: 3.249 ± 0.022	3.957ProGlu: 3.957 ± 0.036	2.055ProPhe: 2.055 ± 0.019	3.852ProGly: 3.852 ± 0.052	1.248ProHis: 1.248 ± 0.017	2.595ProIle: 2.595 ± 0.022	2.867ProLys: 2.867 ± 0.027	4.479ProLeu: 4.479 ± 0.028	1.133ProMet: 1.133 ± 0.015	2.239ProAsn: 2.239 ± 0.022	4.629ProPro: 4.629 ± 0.064	2.457ProGln: 2.457 ± 0.028	3.184ProArg: 3.184 ± 0.034	5.608ProSer: 5.608 ± 0.049	3.988ProThr: 3.988 ± 0.035	3.602ProVal: 3.602 ± 0.029	0.766ProTrp: 0.766 ± 0.01	1.508ProTyr: 1.508 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.37GlnAla: 3.37 ± 0.023	0.464GlnCys: 0.464 ± 0.009	2.316GlnAsp: 2.316 ± 0.023	2.477GlnGlu: 2.477 ± 0.024	1.299GlnPhe: 1.299 ± 0.015	2.528GlnGly: 2.528 ± 0.026	1.076GlnHis: 1.076 ± 0.016	1.895GlnIle: 1.895 ± 0.017	2.014GlnLys: 2.014 ± 0.02	3.344GlnLeu: 3.344 ± 0.03	0.901GlnMet: 0.901 ± 0.014	1.646GlnAsn: 1.646 ± 0.017	2.559GlnPro: 2.559 ± 0.03	2.429GlnGln: 2.429 ± 0.05	2.503GlnArg: 2.503 ± 0.022	3.111GlnSer: 3.111 ± 0.025	2.354GlnThr: 2.354 ± 0.02	2.258GlnVal: 2.258 ± 0.019	0.601GlnTrp: 0.601 ± 0.012	1.173GlnTyr: 1.173 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.176ArgAla: 4.176 ± 0.031	0.722ArgCys: 0.722 ± 0.011	3.367ArgAsp: 3.367 ± 0.032	3.498ArgGlu: 3.498 ± 0.03	2.082ArgPhe: 2.082 ± 0.021	3.497ArgGly: 3.497 ± 0.032	1.501ArgHis: 1.501 ± 0.019	2.865ArgIle: 2.865 ± 0.023	3.271ArgLys: 3.271 ± 0.03	5.208ArgLeu: 5.208 ± 0.039	1.298ArgMet: 1.298 ± 0.014	2.27ArgAsn: 2.27 ± 0.021	3.334ArgPro: 3.334 ± 0.035	2.531ArgGln: 2.531 ± 0.025	4.673ArgArg: 4.673 ± 0.037	4.515ArgSer: 4.515 ± 0.035	3.159ArgThr: 3.159 ± 0.029	3.216ArgVal: 3.216 ± 0.022	0.922ArgTrp: 0.922 ± 0.013	1.658ArgTyr: 1.658 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.122SerAla: 6.122 ± 0.039	0.97SerCys: 0.97 ± 0.014	4.408SerAsp: 4.408 ± 0.034	4.261SerGlu: 4.261 ± 0.032	3.153SerPhe: 3.153 ± 0.027	5.419SerGly: 5.419 ± 0.04	1.931SerHis: 1.931 ± 0.02	4.229SerIle: 4.229 ± 0.027	3.937SerLys: 3.937 ± 0.029	7.082SerLeu: 7.082 ± 0.041	1.807SerMet: 1.807 ± 0.016	3.188SerAsn: 3.188 ± 0.026	5.146SerPro: 5.146 ± 0.049	3.356SerGln: 3.356 ± 0.029	4.785SerArg: 4.785 ± 0.033	8.257SerSer: 8.257 ± 0.064	5.594SerThr: 5.594 ± 0.048	4.64SerVal: 4.64 ± 0.028	1.206SerTrp: 1.206 ± 0.015	2.176SerTyr: 2.176 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.017ThrAla: 5.017 ± 0.032	0.839ThrCys: 0.839 ± 0.013	3.042ThrAsp: 3.042 ± 0.025	3.427ThrGlu: 3.427 ± 0.032	2.294ThrPhe: 2.294 ± 0.023	4.164ThrGly: 4.164 ± 0.038	1.255ThrHis: 1.255 ± 0.014	3.393ThrIle: 3.393 ± 0.039	2.943ThrLys: 2.943 ± 0.027	5.183ThrLeu: 5.183 ± 0.031	1.288ThrMet: 1.288 ± 0.015	2.291ThrAsn: 2.291 ± 0.02	4.182ThrPro: 4.182 ± 0.041	2.236ThrGln: 2.236 ± 0.021	3.126ThrArg: 3.126 ± 0.025	5.439ThrSer: 5.439 ± 0.043	4.671ThrThr: 4.671 ± 0.077	3.892ThrVal: 3.892 ± 0.053	0.934ThrTrp: 0.934 ± 0.013	1.66ThrTyr: 1.66 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.1ValAla: 5.1 ± 0.032	0.877ValCys: 0.877 ± 0.012	3.747ValAsp: 3.747 ± 0.028	3.912ValGlu: 3.912 ± 0.027	2.497ValPhe: 2.497 ± 0.022	3.941ValGly: 3.941 ± 0.034	1.368ValHis: 1.368 ± 0.015	3.116ValIle: 3.116 ± 0.029	3.071ValLys: 3.071 ± 0.025	5.456ValLeu: 5.456 ± 0.035	1.387ValMet: 1.387 ± 0.016	2.301ValAsn: 2.301 ± 0.02	3.573ValPro: 3.573 ± 0.028	2.374ValGln: 2.374 ± 0.023	3.221ValArg: 3.221 ± 0.025	4.737ValSer: 4.737 ± 0.031	3.723ValThr: 3.723 ± 0.045	4.314ValVal: 4.314 ± 0.03	0.881ValTrp: 0.881 ± 0.012	1.767ValTyr: 1.767 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.148TrpAla: 1.148 ± 0.015	0.221TrpCys: 0.221 ± 0.007	0.95TrpAsp: 0.95 ± 0.014	0.889TrpGlu: 0.889 ± 0.011	0.596TrpPhe: 0.596 ± 0.01	0.982TrpGly: 0.982 ± 0.013	0.382TrpHis: 0.382 ± 0.008	0.827TrpIle: 0.827 ± 0.013	0.857TrpLys: 0.857 ± 0.012	1.413TrpLeu: 1.413 ± 0.018	0.389TrpMet: 0.389 ± 0.007	0.675TrpAsn: 0.675 ± 0.011	0.644TrpPro: 0.644 ± 0.011	0.602TrpGln: 0.602 ± 0.011	0.909TrpArg: 0.909 ± 0.013	1.114TrpSer: 1.114 ± 0.013	0.961TrpThr: 0.961 ± 0.015	0.907TrpVal: 0.907 ± 0.011	0.297TrpTrp: 0.297 ± 0.007	0.458TrpTyr: 0.458 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.07TyrAla: 2.07 ± 0.018	0.455TyrCys: 0.455 ± 0.008	1.717TyrAsp: 1.717 ± 0.018	1.609TyrGlu: 1.609 ± 0.018	1.224TyrPhe: 1.224 ± 0.015	2.106TyrGly: 2.106 ± 0.025	0.788TyrHis: 0.788 ± 0.011	1.439TyrIle: 1.439 ± 0.016	1.236TyrLys: 1.236 ± 0.018	2.611TyrLeu: 2.611 ± 0.021	0.66TyrMet: 0.66 ± 0.01	1.206TyrAsn: 1.206 ± 0.017	1.479TyrPro: 1.479 ± 0.017	1.157TyrGln: 1.157 ± 0.013	1.616TyrArg: 1.616 ± 0.018	2.063TyrSer: 2.063 ± 0.02	1.657TyrThr: 1.657 ± 0.02	1.64TyrVal: 1.64 ± 0.019	0.489TyrTrp: 0.489 ± 0.01	0.946TyrTyr: 0.946 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13945 proteins (6439375 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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