Amino acid dipepetide frequency for Trinickia caryophylli (Paraburkholderia caryophylli)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.869AlaAla: 19.869 ± 0.162
1.468AlaCys: 1.468 ± 0.029
6.676AlaAsp: 6.676 ± 0.06
6.427AlaGlu: 6.427 ± 0.066
4.513AlaPhe: 4.513 ± 0.048
11.393AlaGly: 11.393 ± 0.109
3.069AlaHis: 3.069 ± 0.043
5.747AlaIle: 5.747 ± 0.056
3.588AlaLys: 3.588 ± 0.058
15.508AlaLeu: 15.508 ± 0.111
3.309AlaMet: 3.309 ± 0.043
3.113AlaAsn: 3.113 ± 0.054
6.581AlaPro: 6.581 ± 0.079
5.493AlaGln: 5.493 ± 0.074
10.815AlaArg: 10.815 ± 0.092
7.92AlaSer: 7.92 ± 0.08
6.343AlaThr: 6.343 ± 0.068
9.237AlaVal: 9.237 ± 0.07
1.796AlaTrp: 1.796 ± 0.036
2.839AlaTyr: 2.839 ± 0.038
0.0AlaXaa: 0.0 ± 0.0
Cys
1.36CysAla: 1.36 ± 0.027
0.123CysCys: 0.123 ± 0.009
0.557CysAsp: 0.557 ± 0.018
0.529CysGlu: 0.529 ± 0.019
0.338CysPhe: 0.338 ± 0.015
1.013CysGly: 1.013 ± 0.024
0.255CysHis: 0.255 ± 0.013
0.389CysIle: 0.389 ± 0.013
0.212CysLys: 0.212 ± 0.01
0.832CysLeu: 0.832 ± 0.026
0.204CysMet: 0.204 ± 0.011
0.219CysAsn: 0.219 ± 0.01
0.475CysPro: 0.475 ± 0.018
0.206CysGln: 0.206 ± 0.011
0.7CysArg: 0.7 ± 0.024
0.516CysSer: 0.516 ± 0.017
0.498CysThr: 0.498 ± 0.016
0.777CysVal: 0.777 ± 0.021
0.109CysTrp: 0.109 ± 0.007
0.238CysTyr: 0.238 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
8.198AspAla: 8.198 ± 0.08
0.452AspCys: 0.452 ± 0.015
3.096AspAsp: 3.096 ± 0.05
3.639AspGlu: 3.639 ± 0.046
1.847AspPhe: 1.847 ± 0.03
4.672AspGly: 4.672 ± 0.064
1.065AspHis: 1.065 ± 0.022
2.472AspIle: 2.472 ± 0.037
1.461AspLys: 1.461 ± 0.031
4.934AspLeu: 4.934 ± 0.054
1.096AspMet: 1.096 ± 0.024
1.209AspAsn: 1.209 ± 0.032
2.892AspPro: 2.892 ± 0.04
1.353AspGln: 1.353 ± 0.026
3.425AspArg: 3.425 ± 0.037
2.306AspSer: 2.306 ± 0.041
2.776AspThr: 2.776 ± 0.04
4.302AspVal: 4.302 ± 0.05
0.88AspTrp: 0.88 ± 0.022
1.474AspTyr: 1.474 ± 0.026
0.0AspXaa: 0.0 ± 0.0
Glu
7.243GluAla: 7.243 ± 0.075
0.429GluCys: 0.429 ± 0.015
2.059GluAsp: 2.059 ± 0.036
2.422GluGlu: 2.422 ± 0.037
1.703GluPhe: 1.703 ± 0.029
3.502GluGly: 3.502 ± 0.044
1.52GluHis: 1.52 ± 0.03
2.751GluIle: 2.751 ± 0.042
1.669GluLys: 1.669 ± 0.034
5.42GluLeu: 5.42 ± 0.06
1.158GluMet: 1.158 ± 0.026
1.285GluAsn: 1.285 ± 0.028
2.887GluPro: 2.887 ± 0.038
2.398GluGln: 2.398 ± 0.039
5.597GluArg: 5.597 ± 0.066
2.69GluSer: 2.69 ± 0.035
2.885GluThr: 2.885 ± 0.04
3.477GluVal: 3.477 ± 0.047
0.722GluTrp: 0.722 ± 0.02
1.191GluTyr: 1.191 ± 0.029
0.0GluXaa: 0.0 ± 0.0
Phe
4.883PheAla: 4.883 ± 0.059
0.407PheCys: 0.407 ± 0.015
2.695PheAsp: 2.695 ± 0.039
2.09PheGlu: 2.09 ± 0.039
1.393PhePhe: 1.393 ± 0.031
3.56PheGly: 3.56 ± 0.051
0.742PheHis: 0.742 ± 0.02
1.417PheIle: 1.417 ± 0.031
0.972PheLys: 0.972 ± 0.021
2.803PheLeu: 2.803 ± 0.049
0.761PheMet: 0.761 ± 0.022
1.013PheAsn: 1.013 ± 0.026
1.473PhePro: 1.473 ± 0.027
0.88PheGln: 0.88 ± 0.024
2.009PheArg: 2.009 ± 0.029
2.309PheSer: 2.309 ± 0.033
1.826PheThr: 1.826 ± 0.029
3.238PheVal: 3.238 ± 0.048
0.489PheTrp: 0.489 ± 0.016
0.876PheTyr: 0.876 ± 0.022
0.0PheXaa: 0.0 ± 0.0
Gly
10.239GlyAla: 10.239 ± 0.107
0.893GlyCys: 0.893 ± 0.023
3.994GlyAsp: 3.994 ± 0.051
4.585GlyGlu: 4.585 ± 0.051
3.261GlyPhe: 3.261 ± 0.046
7.057GlyGly: 7.057 ± 0.101
1.975GlyHis: 1.975 ± 0.035
4.193GlyIle: 4.193 ± 0.043
2.98GlyLys: 2.98 ± 0.041
7.784GlyLeu: 7.784 ± 0.068
2.153GlyMet: 2.153 ± 0.036
2.384GlyAsn: 2.384 ± 0.063
3.05GlyPro: 3.05 ± 0.041
2.692GlyGln: 2.692 ± 0.046
5.793GlyArg: 5.793 ± 0.059
4.601GlySer: 4.601 ± 0.074
4.922GlyThr: 4.922 ± 0.068
6.455GlyVal: 6.455 ± 0.068
1.341GlyTrp: 1.341 ± 0.025
2.406GlyTyr: 2.406 ± 0.034
0.0GlyXaa: 0.0 ± 0.0
His
3.237HisAla: 3.237 ± 0.044
0.271HisCys: 0.271 ± 0.013
1.361HisAsp: 1.361 ± 0.029
1.272HisGlu: 1.272 ± 0.027
0.92HisPhe: 0.92 ± 0.023
2.195HisGly: 2.195 ± 0.036
0.585HisHis: 0.585 ± 0.018
0.897HisIle: 0.897 ± 0.018
0.459HisLys: 0.459 ± 0.017
2.125HisLeu: 2.125 ± 0.034
0.522HisMet: 0.522 ± 0.015
0.504HisAsn: 0.504 ± 0.016
1.482HisPro: 1.482 ± 0.03
0.588HisGln: 0.588 ± 0.018
1.744HisArg: 1.744 ± 0.032
1.031HisSer: 1.031 ± 0.023
1.05HisThr: 1.05 ± 0.024
1.746HisVal: 1.746 ± 0.028
0.391HisTrp: 0.391 ± 0.015
0.677HisTyr: 0.677 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
7.004IleAla: 7.004 ± 0.071
0.429IleCys: 0.429 ± 0.014
3.545IleAsp: 3.545 ± 0.047
3.477IleGlu: 3.477 ± 0.042
1.311IlePhe: 1.311 ± 0.029
4.677IleGly: 4.677 ± 0.054
0.853IleHis: 0.853 ± 0.022
1.33IleIle: 1.33 ± 0.034
1.203IleLys: 1.203 ± 0.026
3.007IleLeu: 3.007 ± 0.041
0.709IleMet: 0.709 ± 0.02
1.184IleAsn: 1.184 ± 0.028
1.916IlePro: 1.916 ± 0.033
1.042IleGln: 1.042 ± 0.024
2.711IleArg: 2.711 ± 0.038
2.328IleSer: 2.328 ± 0.04
1.982IleThr: 1.982 ± 0.04
4.594IleVal: 4.594 ± 0.057
0.491IleTrp: 0.491 ± 0.016
0.958IleTyr: 0.958 ± 0.021
0.0IleXaa: 0.0 ± 0.0
Lys
3.449LysAla: 3.449 ± 0.046
0.16LysCys: 0.16 ± 0.009
1.326LysAsp: 1.326 ± 0.03
1.297LysGlu: 1.297 ± 0.032
0.806LysPhe: 0.806 ± 0.019
1.982LysGly: 1.982 ± 0.038
0.631LysHis: 0.631 ± 0.016
1.427LysIle: 1.427 ± 0.034
1.046LysLys: 1.046 ± 0.033
3.092LysLeu: 3.092 ± 0.046
0.69LysMet: 0.69 ± 0.019
0.744LysAsn: 0.744 ± 0.021
1.814LysPro: 1.814 ± 0.035
1.087LysGln: 1.087 ± 0.024
2.294LysArg: 2.294 ± 0.035
1.543LysSer: 1.543 ± 0.029
1.774LysThr: 1.774 ± 0.032
1.984LysVal: 1.984 ± 0.036
0.352LysTrp: 0.352 ± 0.014
0.648LysTyr: 0.648 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
15.377LeuAla: 15.377 ± 0.117
0.983LeuCys: 0.983 ± 0.027
6.03LeuAsp: 6.03 ± 0.049
5.185LeuGlu: 5.185 ± 0.062
3.471LeuPhe: 3.471 ± 0.05
8.153LeuGly: 8.153 ± 0.081
2.216LeuHis: 2.216 ± 0.037
4.168LeuIle: 4.168 ± 0.056
2.92LeuLys: 2.92 ± 0.046
9.662LeuLeu: 9.662 ± 0.099
2.142LeuMet: 2.142 ± 0.037
2.411LeuAsn: 2.411 ± 0.042
5.781LeuPro: 5.781 ± 0.062
3.0LeuGln: 3.0 ± 0.037
7.357LeuArg: 7.357 ± 0.072
6.198LeuSer: 6.198 ± 0.067
5.317LeuThr: 5.317 ± 0.064
7.789LeuVal: 7.789 ± 0.075
1.093LeuTrp: 1.093 ± 0.025
2.141LeuTyr: 2.141 ± 0.038
0.0LeuXaa: 0.0 ± 0.0
Met
2.614MetAla: 2.614 ± 0.038
0.16MetCys: 0.16 ± 0.01
0.88MetAsp: 0.88 ± 0.024
0.847MetGlu: 0.847 ± 0.021
0.704MetPhe: 0.704 ± 0.02
1.501MetGly: 1.501 ± 0.029
0.547MetHis: 0.547 ± 0.016
1.043MetIle: 1.043 ± 0.025
0.97MetLys: 0.97 ± 0.022
2.621MetLeu: 2.621 ± 0.038
0.559MetMet: 0.559 ± 0.021
0.848MetAsn: 0.848 ± 0.019
1.5MetPro: 1.5 ± 0.026
0.96MetGln: 0.96 ± 0.02
1.924MetArg: 1.924 ± 0.037
1.723MetSer: 1.723 ± 0.033
1.656MetThr: 1.656 ± 0.031
1.313MetVal: 1.313 ± 0.026
0.205MetTrp: 0.205 ± 0.011
0.379MetTyr: 0.379 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
3.519AsnAla: 3.519 ± 0.059
0.244AsnCys: 0.244 ± 0.013
1.419AsnAsp: 1.419 ± 0.029
1.31AsnGlu: 1.31 ± 0.024
0.868AsnPhe: 0.868 ± 0.022
2.453AsnGly: 2.453 ± 0.053
0.493AsnHis: 0.493 ± 0.018
1.094AsnIle: 1.094 ± 0.028
0.595AsnLys: 0.595 ± 0.02
2.486AsnLeu: 2.486 ± 0.042
0.513AsnMet: 0.513 ± 0.017
0.715AsnAsn: 0.715 ± 0.026
1.629AsnPro: 1.629 ± 0.032
0.781AsnGln: 0.781 ± 0.025
1.726AsnArg: 1.726 ± 0.031
1.176AsnSer: 1.176 ± 0.036
1.357AsnThr: 1.357 ± 0.034
2.184AsnVal: 2.184 ± 0.042
0.407AsnTrp: 0.407 ± 0.015
0.671AsnTyr: 0.671 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
7.211ProAla: 7.211 ± 0.076
0.391ProCys: 0.391 ± 0.016
3.201ProAsp: 3.201 ± 0.042
3.052ProGlu: 3.052 ± 0.043
1.956ProPhe: 1.956 ± 0.035
4.505ProGly: 4.505 ± 0.061
1.271ProHis: 1.271 ± 0.03
2.128ProIle: 2.128 ± 0.034
1.307ProLys: 1.307 ± 0.026
5.262ProLeu: 5.262 ± 0.056
1.119ProMet: 1.119 ± 0.024
1.362ProAsn: 1.362 ± 0.029
2.734ProPro: 2.734 ± 0.047
1.795ProGln: 1.795 ± 0.036
3.315ProArg: 3.315 ± 0.046
2.997ProSer: 2.997 ± 0.044
2.497ProThr: 2.497 ± 0.034
4.124ProVal: 4.124 ± 0.049
0.67ProTrp: 0.67 ± 0.019
1.244ProTyr: 1.244 ± 0.027
0.0ProXaa: 0.0 ± 0.0
Gln
4.688GlnAla: 4.688 ± 0.057
0.286GlnCys: 0.286 ± 0.013
1.211GlnAsp: 1.211 ± 0.027
1.26GlnGlu: 1.26 ± 0.028
1.193GlnPhe: 1.193 ± 0.027
2.345GlnGly: 2.345 ± 0.038
0.802GlnHis: 0.802 ± 0.02
1.761GlnIle: 1.761 ± 0.032
0.918GlnLys: 0.918 ± 0.023
3.556GlnLeu: 3.556 ± 0.046
0.974GlnMet: 0.974 ± 0.023
0.791GlnAsn: 0.791 ± 0.02
2.01GlnPro: 2.01 ± 0.037
1.642GlnGln: 1.642 ± 0.036
2.849GlnArg: 2.849 ± 0.04
1.935GlnSer: 1.935 ± 0.034
1.936GlnThr: 1.936 ± 0.033
2.219GlnVal: 2.219 ± 0.036
0.585GlnTrp: 0.585 ± 0.019
0.879GlnTyr: 0.879 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
9.49ArgAla: 9.49 ± 0.09
0.696ArgCys: 0.696 ± 0.022
3.863ArgAsp: 3.863 ± 0.047
4.687ArgGlu: 4.687 ± 0.058
3.182ArgPhe: 3.182 ± 0.042
5.069ArgGly: 5.069 ± 0.054
2.074ArgHis: 2.074 ± 0.038
3.869ArgIle: 3.869 ± 0.047
1.94ArgLys: 1.94 ± 0.037
7.912ArgLeu: 7.912 ± 0.082
1.975ArgMet: 1.975 ± 0.033
1.887ArgAsn: 1.887 ± 0.033
3.354ArgPro: 3.354 ± 0.049
2.595ArgGln: 2.595 ± 0.039
6.147ArgArg: 6.147 ± 0.076
3.639ArgSer: 3.639 ± 0.043
3.798ArgThr: 3.798 ± 0.045
5.411ArgVal: 5.411 ± 0.057
1.128ArgTrp: 1.128 ± 0.03
2.224ArgTyr: 2.224 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
7.104SerAla: 7.104 ± 0.073
0.474SerCys: 0.474 ± 0.016
2.749SerAsp: 2.749 ± 0.04
2.649SerGlu: 2.649 ± 0.04
2.098SerPhe: 2.098 ± 0.032
5.487SerGly: 5.487 ± 0.076
1.226SerHis: 1.226 ± 0.031
2.678SerIle: 2.678 ± 0.04
1.467SerLys: 1.467 ± 0.032
5.783SerLeu: 5.783 ± 0.064
1.379SerMet: 1.379 ± 0.029
1.57SerAsn: 1.57 ± 0.04
2.983SerPro: 2.983 ± 0.044
1.761SerGln: 1.761 ± 0.034
3.853SerArg: 3.853 ± 0.048
3.378SerSer: 3.378 ± 0.054
3.04SerThr: 3.04 ± 0.052
4.25SerVal: 4.25 ± 0.046
0.661SerTrp: 0.661 ± 0.021
1.345SerTyr: 1.345 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
6.133ThrAla: 6.133 ± 0.071
0.419ThrCys: 0.419 ± 0.014
2.591ThrAsp: 2.591 ± 0.042
2.285ThrGlu: 2.285 ± 0.037
1.891ThrPhe: 1.891 ± 0.032
4.688ThrGly: 4.688 ± 0.067
1.231ThrHis: 1.231 ± 0.027
2.565ThrIle: 2.565 ± 0.042
1.23ThrLys: 1.23 ± 0.026
6.43ThrLeu: 6.43 ± 0.068
1.209ThrMet: 1.209 ± 0.025
1.358ThrAsn: 1.358 ± 0.04
3.364ThrPro: 3.364 ± 0.048
1.803ThrGln: 1.803 ± 0.034
3.611ThrArg: 3.611 ± 0.046
2.985ThrSer: 2.985 ± 0.053
2.8ThrThr: 2.8 ± 0.062
4.305ThrVal: 4.305 ± 0.058
0.624ThrTrp: 0.624 ± 0.019
1.21ThrTyr: 1.21 ± 0.03
0.0ThrXaa: 0.0 ± 0.0
Val
9.944ValAla: 9.944 ± 0.086
0.834ValCys: 0.834 ± 0.019
4.335ValAsp: 4.335 ± 0.049
4.186ValGlu: 4.186 ± 0.046
2.824ValPhe: 2.824 ± 0.041
5.489ValGly: 5.489 ± 0.069
1.582ValHis: 1.582 ± 0.03
3.373ValIle: 3.373 ± 0.047
2.274ValLys: 2.274 ± 0.043
7.804ValLeu: 7.804 ± 0.08
1.7ValMet: 1.7 ± 0.029
2.055ValAsn: 2.055 ± 0.035
4.27ValPro: 4.27 ± 0.05
2.301ValGln: 2.301 ± 0.036
5.57ValArg: 5.57 ± 0.061
4.646ValSer: 4.646 ± 0.058
4.397ValThr: 4.397 ± 0.051
6.312ValVal: 6.312 ± 0.071
0.924ValTrp: 0.924 ± 0.027
1.691ValTyr: 1.691 ± 0.029
0.0ValXaa: 0.0 ± 0.0
Trp
1.247TrpAla: 1.247 ± 0.031
0.148TrpCys: 0.148 ± 0.01
0.556TrpAsp: 0.556 ± 0.018
0.497TrpGlu: 0.497 ± 0.017
0.553TrpPhe: 0.553 ± 0.016
0.838TrpGly: 0.838 ± 0.02
0.419TrpHis: 0.419 ± 0.014
0.659TrpIle: 0.659 ± 0.02
0.381TrpLys: 0.381 ± 0.016
1.855TrpLeu: 1.855 ± 0.037
0.343TrpMet: 0.343 ± 0.014
0.406TrpAsn: 0.406 ± 0.015
0.703TrpPro: 0.703 ± 0.022
0.671TrpGln: 0.671 ± 0.019
1.316TrpArg: 1.316 ± 0.026
0.794TrpSer: 0.794 ± 0.022
0.657TrpThr: 0.657 ± 0.02
0.894TrpVal: 0.894 ± 0.024
0.225TrpTrp: 0.225 ± 0.01
0.314TrpTyr: 0.314 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.896TyrAla: 2.896 ± 0.04
0.283TyrCys: 0.283 ± 0.015
1.402TyrAsp: 1.402 ± 0.031
1.313TyrGlu: 1.313 ± 0.03
1.002TyrPhe: 1.002 ± 0.024
2.181TyrGly: 2.181 ± 0.038
0.501TyrHis: 0.501 ± 0.018
0.792TyrIle: 0.792 ± 0.02
0.554TyrLys: 0.554 ± 0.017
2.521TyrLeu: 2.521 ± 0.035
0.437TyrMet: 0.437 ± 0.016
0.583TyrAsn: 0.583 ± 0.018
1.244TyrPro: 1.244 ± 0.025
0.79TyrGln: 0.79 ± 0.022
2.184TyrArg: 2.184 ± 0.034
1.221TyrSer: 1.221 ± 0.026
1.218TyrThr: 1.218 ± 0.025
1.9TyrVal: 1.9 ± 0.031
0.385TyrTrp: 0.385 ± 0.014
0.666TyrTyr: 0.666 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5785 proteins (1921830 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski