Amino acid dipepetide frequency for Tamaricihabitans halophyticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.237AlaAla: 19.237 ± 0.151	0.998AlaCys: 0.998 ± 0.029	8.192AlaAsp: 8.192 ± 0.079	10.826AlaGlu: 10.826 ± 0.087	3.326AlaPhe: 3.326 ± 0.045	12.888AlaGly: 12.888 ± 0.104	2.524AlaHis: 2.524 ± 0.041	5.047AlaIle: 5.047 ± 0.06	2.904AlaLys: 2.904 ± 0.046	13.481AlaLeu: 13.481 ± 0.122	2.667AlaMet: 2.667 ± 0.038	2.721AlaAsn: 2.721 ± 0.04	5.765AlaPro: 5.765 ± 0.07	3.895AlaGln: 3.895 ± 0.044	9.628AlaArg: 9.628 ± 0.083	6.379AlaSer: 6.379 ± 0.063	7.239AlaThr: 7.239 ± 0.072	11.17AlaVal: 11.17 ± 0.088	1.635AlaTrp: 1.635 ± 0.032	2.199AlaTyr: 2.199 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	1.229CysAla: 1.229 ± 0.033	0.104CysCys: 0.104 ± 0.007	0.441CysAsp: 0.441 ± 0.016	0.345CysGlu: 0.345 ± 0.014	0.247CysPhe: 0.247 ± 0.013	0.914CysGly: 0.914 ± 0.025	0.174CysHis: 0.174 ± 0.009	0.203CysIle: 0.203 ± 0.01	0.111CysLys: 0.111 ± 0.008	0.693CysLeu: 0.693 ± 0.02	0.126CysMet: 0.126 ± 0.008	0.128CysAsn: 0.128 ± 0.009	0.449CysPro: 0.449 ± 0.016	0.238CysGln: 0.238 ± 0.012	0.552CysArg: 0.552 ± 0.02	0.424CysSer: 0.424 ± 0.018	0.558CysThr: 0.558 ± 0.022	0.666CysVal: 0.666 ± 0.02	0.145CysTrp: 0.145 ± 0.009	0.221CysTyr: 0.221 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.997AspAla: 6.997 ± 0.061	0.444AspCys: 0.444 ± 0.016	3.281AspAsp: 3.281 ± 0.046	4.247AspGlu: 4.247 ± 0.05	1.534AspPhe: 1.534 ± 0.03	5.684AspGly: 5.684 ± 0.069	1.095AspHis: 1.095 ± 0.024	2.201AspIle: 2.201 ± 0.041	1.129AspLys: 1.129 ± 0.032	5.514AspLeu: 5.514 ± 0.062	0.938AspMet: 0.938 ± 0.022	1.148AspAsn: 1.148 ± 0.025	4.187AspPro: 4.187 ± 0.049	2.058AspGln: 2.058 ± 0.034	4.577AspArg: 4.577 ± 0.051	2.88AspSer: 2.88 ± 0.041	3.215AspThr: 3.215 ± 0.041	4.797AspVal: 4.797 ± 0.051	1.014AspTrp: 1.014 ± 0.025	1.382AspTyr: 1.382 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	6.537GluAla: 6.537 ± 0.073	0.394GluCys: 0.394 ± 0.014	2.535GluAsp: 2.535 ± 0.041	2.823GluGlu: 2.823 ± 0.046	1.987GluPhe: 1.987 ± 0.035	3.5GluGly: 3.5 ± 0.045	1.832GluHis: 1.832 ± 0.028	2.578GluIle: 2.578 ± 0.038	1.002GluLys: 1.002 ± 0.028	9.238GluLeu: 9.238 ± 0.095	0.997GluMet: 0.997 ± 0.021	1.069GluAsn: 1.069 ± 0.023	3.886GluPro: 3.886 ± 0.06	3.238GluGln: 3.238 ± 0.056	5.655GluArg: 5.655 ± 0.06	3.06GluSer: 3.06 ± 0.049	2.92GluThr: 2.92 ± 0.037	5.061GluVal: 5.061 ± 0.056	0.826GluTrp: 0.826 ± 0.022	1.249GluTyr: 1.249 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.159PheAla: 4.159 ± 0.057	0.271PheCys: 0.271 ± 0.014	2.093PheAsp: 2.093 ± 0.036	1.456PheGlu: 1.456 ± 0.025	0.853PhePhe: 0.853 ± 0.027	3.533PheGly: 3.533 ± 0.044	0.6PheHis: 0.6 ± 0.019	0.822PheIle: 0.822 ± 0.025	0.331PheLys: 0.331 ± 0.015	2.659PheLeu: 2.659 ± 0.049	0.394PheMet: 0.394 ± 0.015	0.567PheAsn: 0.567 ± 0.019	1.349PhePro: 1.349 ± 0.025	0.738PheGln: 0.738 ± 0.019	1.834PheArg: 1.834 ± 0.026	1.537PheSer: 1.537 ± 0.031	1.844PheThr: 1.844 ± 0.037	2.43PheVal: 2.43 ± 0.044	0.431PheTrp: 0.431 ± 0.016	0.609PheTyr: 0.609 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	10.65GlyAla: 10.65 ± 0.08	0.87GlyCys: 0.87 ± 0.026	4.439GlyAsp: 4.439 ± 0.053	5.407GlyGlu: 5.407 ± 0.051	3.067GlyPhe: 3.067 ± 0.041	7.964GlyGly: 7.964 ± 0.092	1.9GlyHis: 1.9 ± 0.033	4.103GlyIle: 4.103 ± 0.047	2.538GlyLys: 2.538 ± 0.041	9.281GlyLeu: 9.281 ± 0.077	2.38GlyMet: 2.38 ± 0.039	1.977GlyAsn: 1.977 ± 0.039	4.247GlyPro: 4.247 ± 0.052	3.285GlyGln: 3.285 ± 0.05	6.042GlyArg: 6.042 ± 0.057	5.309GlySer: 5.309 ± 0.062	5.579GlyThr: 5.579 ± 0.063	7.605GlyVal: 7.605 ± 0.079	1.741GlyTrp: 1.741 ± 0.032	2.514GlyTyr: 2.514 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	2.695HisAla: 2.695 ± 0.043	0.227HisCys: 0.227 ± 0.011	1.225HisAsp: 1.225 ± 0.025	1.233HisGlu: 1.233 ± 0.026	0.552HisPhe: 0.552 ± 0.019	2.328HisGly: 2.328 ± 0.037	0.52HisHis: 0.52 ± 0.017	0.713HisIle: 0.713 ± 0.022	0.299HisLys: 0.299 ± 0.015	2.014HisLeu: 2.014 ± 0.031	0.327HisMet: 0.327 ± 0.014	0.425HisAsn: 0.425 ± 0.014	1.535HisPro: 1.535 ± 0.028	0.723HisGln: 0.723 ± 0.02	1.888HisArg: 1.888 ± 0.034	0.993HisSer: 0.993 ± 0.022	1.271HisThr: 1.271 ± 0.026	1.496HisVal: 1.496 ± 0.029	0.358HisTrp: 0.358 ± 0.014	0.491HisTyr: 0.491 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	6.089IleAla: 6.089 ± 0.068	0.349IleCys: 0.349 ± 0.014	2.586IleAsp: 2.586 ± 0.04	2.433IleGlu: 2.433 ± 0.038	0.848IlePhe: 0.848 ± 0.024	4.476IleGly: 4.476 ± 0.058	0.626IleHis: 0.626 ± 0.017	1.207IleIle: 1.207 ± 0.027	0.688IleLys: 0.688 ± 0.021	2.775IleLeu: 2.775 ± 0.048	0.536IleMet: 0.536 ± 0.016	0.905IleAsn: 0.905 ± 0.022	2.041IlePro: 2.041 ± 0.033	0.886IleGln: 0.886 ± 0.022	2.557IleArg: 2.557 ± 0.035	2.203IleSer: 2.203 ± 0.034	2.473IleThr: 2.473 ± 0.037	3.329IleVal: 3.329 ± 0.049	0.428IleTrp: 0.428 ± 0.015	0.681IleTyr: 0.681 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.272LysAla: 2.272 ± 0.041	0.097LysCys: 0.097 ± 0.007	0.974LysAsp: 0.974 ± 0.027	1.005LysGlu: 1.005 ± 0.027	0.466LysPhe: 0.466 ± 0.016	1.286LysGly: 1.286 ± 0.029	0.474LysHis: 0.474 ± 0.016	0.836LysIle: 0.836 ± 0.023	0.474LysLys: 0.474 ± 0.021	2.198LysLeu: 2.198 ± 0.036	0.373LysMet: 0.373 ± 0.013	0.383LysAsn: 0.383 ± 0.014	1.345LysPro: 1.345 ± 0.03	0.775LysGln: 0.775 ± 0.019	1.535LysArg: 1.535 ± 0.034	0.989LysSer: 0.989 ± 0.026	1.057LysThr: 1.057 ± 0.025	1.727LysVal: 1.727 ± 0.033	0.216LysTrp: 0.216 ± 0.01	0.412LysTyr: 0.412 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	16.481LeuAla: 16.481 ± 0.137	0.885LeuCys: 0.885 ± 0.024	6.927LeuAsp: 6.927 ± 0.071	4.491LeuGlu: 4.491 ± 0.054	2.816LeuPhe: 2.816 ± 0.053	9.953LeuGly: 9.953 ± 0.082	2.236LeuHis: 2.236 ± 0.031	3.861LeuIle: 3.861 ± 0.052	1.243LeuLys: 1.243 ± 0.026	11.799LeuLeu: 11.799 ± 0.132	1.393LeuMet: 1.393 ± 0.028	1.924LeuAsn: 1.924 ± 0.034	6.289LeuPro: 6.289 ± 0.064	1.99LeuGln: 1.99 ± 0.033	9.556LeuArg: 9.556 ± 0.099	5.721LeuSer: 5.721 ± 0.047	6.367LeuThr: 6.367 ± 0.062	9.445LeuVal: 9.445 ± 0.094	1.222LeuTrp: 1.222 ± 0.025	1.69LeuTyr: 1.69 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.307MetAla: 2.307 ± 0.032	0.126MetCys: 0.126 ± 0.008	0.894MetAsp: 0.894 ± 0.021	0.638MetGlu: 0.638 ± 0.018	0.569MetPhe: 0.569 ± 0.017	1.231MetGly: 1.231 ± 0.026	0.379MetHis: 0.379 ± 0.012	0.787MetIle: 0.787 ± 0.022	0.311MetLys: 0.311 ± 0.012	2.093MetLeu: 2.093 ± 0.035	0.317MetMet: 0.317 ± 0.015	0.429MetAsn: 0.429 ± 0.015	1.144MetPro: 1.144 ± 0.026	0.476MetGln: 0.476 ± 0.016	1.652MetArg: 1.652 ± 0.03	1.416MetSer: 1.416 ± 0.028	1.541MetThr: 1.541 ± 0.031	1.434MetVal: 1.434 ± 0.032	0.221MetTrp: 0.221 ± 0.01	0.312MetTyr: 0.312 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.5AsnAla: 2.5 ± 0.038	0.176AsnCys: 0.176 ± 0.008	1.045AsnAsp: 1.045 ± 0.022	1.101AsnGlu: 1.101 ± 0.025	0.541AsnPhe: 0.541 ± 0.017	1.988AsnGly: 1.988 ± 0.034	0.423AsnHis: 0.423 ± 0.015	0.771AsnIle: 0.771 ± 0.02	0.417AsnLys: 0.417 ± 0.016	1.91AsnLeu: 1.91 ± 0.032	0.366AsnMet: 0.366 ± 0.015	0.473AsnAsn: 0.473 ± 0.016	1.603AsnPro: 1.603 ± 0.032	0.737AsnGln: 0.737 ± 0.022	1.512AsnArg: 1.512 ± 0.024	1.058AsnSer: 1.058 ± 0.026	1.266AsnThr: 1.266 ± 0.034	1.585AsnVal: 1.585 ± 0.035	0.353AsnTrp: 0.353 ± 0.012	0.514AsnTyr: 0.514 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	7.703ProAla: 7.703 ± 0.084	0.306ProCys: 0.306 ± 0.014	4.245ProAsp: 4.245 ± 0.053	4.495ProGlu: 4.495 ± 0.053	1.478ProPhe: 1.478 ± 0.024	5.377ProGly: 5.377 ± 0.062	1.107ProHis: 1.107 ± 0.027	1.889ProIle: 1.889 ± 0.027	1.159ProLys: 1.159 ± 0.024	4.792ProLeu: 4.792 ± 0.051	1.08ProMet: 1.08 ± 0.022	1.281ProAsn: 1.281 ± 0.028	2.973ProPro: 2.973 ± 0.059	1.579ProGln: 1.579 ± 0.032	3.552ProArg: 3.552 ± 0.046	2.977ProSer: 2.977 ± 0.04	3.291ProThr: 3.291 ± 0.043	4.977ProVal: 4.977 ± 0.051	0.817ProTrp: 0.817 ± 0.022	1.149ProTyr: 1.149 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.813GlnAla: 3.813 ± 0.055	0.187GlnCys: 0.187 ± 0.011	1.49GlnAsp: 1.49 ± 0.03	1.545GlnGlu: 1.545 ± 0.032	0.845GlnPhe: 0.845 ± 0.022	2.174GlnGly: 2.174 ± 0.038	0.794GlnHis: 0.794 ± 0.021	1.193GlnIle: 1.193 ± 0.026	0.39GlnLys: 0.39 ± 0.016	4.379GlnLeu: 4.379 ± 0.058	0.488GlnMet: 0.488 ± 0.017	0.53GlnAsn: 0.53 ± 0.017	2.362GlnPro: 2.362 ± 0.056	1.586GlnGln: 1.586 ± 0.036	3.125GlnArg: 3.125 ± 0.035	1.41GlnSer: 1.41 ± 0.029	1.43GlnThr: 1.43 ± 0.029	2.755GlnVal: 2.755 ± 0.044	0.507GlnTrp: 0.507 ± 0.017	0.6GlnTyr: 0.6 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	9.945ArgAla: 9.945 ± 0.097	0.603ArgCys: 0.603 ± 0.019	4.109ArgAsp: 4.109 ± 0.049	4.737ArgGlu: 4.737 ± 0.06	2.435ArgPhe: 2.435 ± 0.042	5.63ArgGly: 5.63 ± 0.049	1.774ArgHis: 1.774 ± 0.027	3.498ArgIle: 3.498 ± 0.045	1.892ArgLys: 1.892 ± 0.034	8.333ArgLeu: 8.333 ± 0.075	1.882ArgMet: 1.882 ± 0.033	1.616ArgAsn: 1.616 ± 0.03	4.013ArgPro: 4.013 ± 0.049	2.762ArgGln: 2.762 ± 0.044	6.538ArgArg: 6.538 ± 0.08	3.987ArgSer: 3.987 ± 0.046	4.574ArgThr: 4.574 ± 0.047	5.826ArgVal: 5.826 ± 0.058	1.332ArgTrp: 1.332 ± 0.027	1.927ArgTyr: 1.927 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	7.409SerAla: 7.409 ± 0.068	0.461SerCys: 0.461 ± 0.017	2.74SerAsp: 2.74 ± 0.036	2.911SerGlu: 2.911 ± 0.034	1.596SerPhe: 1.596 ± 0.031	5.925SerGly: 5.925 ± 0.063	0.889SerHis: 0.889 ± 0.021	1.933SerIle: 1.933 ± 0.033	1.097SerLys: 1.097 ± 0.024	4.621SerLeu: 4.621 ± 0.051	1.232SerMet: 1.232 ± 0.024	1.063SerAsn: 1.063 ± 0.021	2.808SerPro: 2.808 ± 0.039	1.392SerGln: 1.392 ± 0.028	3.487SerArg: 3.487 ± 0.047	3.119SerSer: 3.119 ± 0.052	3.729SerThr: 3.729 ± 0.047	4.447SerVal: 4.447 ± 0.055	1.078SerTrp: 1.078 ± 0.027	1.326SerTyr: 1.326 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	7.829ThrAla: 7.829 ± 0.06	0.397ThrCys: 0.397 ± 0.013	3.583ThrAsp: 3.583 ± 0.051	4.448ThrGlu: 4.448 ± 0.055	1.539ThrPhe: 1.539 ± 0.027	6.156ThrGly: 6.156 ± 0.065	1.074ThrHis: 1.074 ± 0.025	2.246ThrIle: 2.246 ± 0.033	1.261ThrLys: 1.261 ± 0.031	5.282ThrLeu: 5.282 ± 0.053	1.147ThrMet: 1.147 ± 0.026	1.21ThrAsn: 1.21 ± 0.025	3.325ThrPro: 3.325 ± 0.041	1.423ThrGln: 1.423 ± 0.027	3.564ThrArg: 3.564 ± 0.044	3.288ThrSer: 3.288 ± 0.043	3.566ThrThr: 3.566 ± 0.055	5.777ThrVal: 5.777 ± 0.058	0.756ThrTrp: 0.756 ± 0.02	1.109ThrTyr: 1.109 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	10.85ValAla: 10.85 ± 0.091	0.71ValCys: 0.71 ± 0.021	5.563ValAsp: 5.563 ± 0.053	4.597ValGlu: 4.597 ± 0.062	2.581ValPhe: 2.581 ± 0.043	6.815ValGly: 6.815 ± 0.068	2.056ValHis: 2.056 ± 0.035	3.134ValIle: 3.134 ± 0.045	1.174ValLys: 1.174 ± 0.028	10.632ValLeu: 10.632 ± 0.099	1.13ValMet: 1.13 ± 0.027	1.81ValAsn: 1.81 ± 0.032	4.826ValPro: 4.826 ± 0.047	2.212ValGln: 2.212 ± 0.036	6.89ValArg: 6.89 ± 0.06	4.628ValSer: 4.628 ± 0.052	4.977ValThr: 4.977 ± 0.052	7.769ValVal: 7.769 ± 0.089	1.065ValTrp: 1.065 ± 0.026	1.494ValTyr: 1.494 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.487TrpAla: 1.487 ± 0.032	0.164TrpCys: 0.164 ± 0.009	0.716TrpAsp: 0.716 ± 0.02	0.633TrpGlu: 0.633 ± 0.018	0.539TrpPhe: 0.539 ± 0.017	0.976TrpGly: 0.976 ± 0.022	0.373TrpHis: 0.373 ± 0.013	0.574TrpIle: 0.574 ± 0.019	0.216TrpLys: 0.216 ± 0.012	2.091TrpLeu: 2.091 ± 0.038	0.285TrpMet: 0.285 ± 0.011	0.308TrpAsn: 0.308 ± 0.013	0.82TrpPro: 0.82 ± 0.022	0.781TrpGln: 0.781 ± 0.026	1.411TrpArg: 1.411 ± 0.028	0.887TrpSer: 0.887 ± 0.022	0.882TrpThr: 0.882 ± 0.022	1.057TrpVal: 1.057 ± 0.027	0.357TrpTrp: 0.357 ± 0.015	0.313TrpTyr: 0.313 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.533TyrAla: 2.533 ± 0.033	0.198TyrCys: 0.198 ± 0.01	1.246TyrAsp: 1.246 ± 0.026	1.018TyrGlu: 1.018 ± 0.026	0.693TyrPhe: 0.693 ± 0.022	2.103TyrGly: 2.103 ± 0.036	0.463TyrHis: 0.463 ± 0.016	0.519TyrIle: 0.519 ± 0.016	0.257TyrLys: 0.257 ± 0.012	2.502TyrLeu: 2.502 ± 0.037	0.218TyrMet: 0.218 ± 0.011	0.37TyrAsn: 0.37 ± 0.016	1.259TyrPro: 1.259 ± 0.026	0.828TyrGln: 0.828 ± 0.02	1.86TyrArg: 1.86 ± 0.031	0.999TyrSer: 0.999 ± 0.025	1.2TyrThr: 1.2 ± 0.026	1.558TyrVal: 1.558 ± 0.033	0.367TyrTrp: 0.367 ± 0.013	0.496TyrTyr: 0.496 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5978 proteins (1946036 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---