Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Chloroflexi; Anaerolineae; Anaerolineales; Anaerolineaceae; Anaerolinea; Anaerolinea thermophila
Average proteome isoelectric point is 6.41
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Virtual 2D-PAGE plot for 3110 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|E8N2V1|E8N2V1_ANATU Terminase_6C domain-containing protein OS=Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1) OX=926569 GN=ANT_30750 PE=4 SV=1
MM1 pKa = 7.32HH2 pKa = 7.51KK3 pKa = 10.41SVALRR8 pKa = 11.84IGSIWGIFLMLIGALPIVPVQARR31 pKa = 11.84PLAQPTTDD39 pKa = 2.73VSLNVPAEE47 pKa = 4.22TMLGQPFTFTVTFDD61 pKa = 3.95NNGTAPGYY69 pKa = 11.02GPFIDD74 pKa = 6.14LILPATGADD83 pKa = 3.73GDD85 pKa = 4.76DD86 pKa = 3.47GLTFAGATYY95 pKa = 10.66LGLPLSSVVLTFPAPTGCVAHH116 pKa = 7.12PYY118 pKa = 10.71AVDD121 pKa = 3.31TSGAPVQVCGTPGDD135 pKa = 3.78QLVVLLLPFGSFFPDD150 pKa = 3.36QPPVEE155 pKa = 4.51VNVSVNMNNYY165 pKa = 10.25ADD167 pKa = 3.88VDD169 pKa = 4.12TPLTIQARR177 pKa = 11.84GGYY180 pKa = 8.81QFGEE184 pKa = 4.68TPVSDD189 pKa = 4.2PSTDD193 pKa = 3.39PSIVGGWTTASTTPTLIRR211 pKa = 11.84VVKK214 pKa = 9.5TYY216 pKa = 10.61LGPEE220 pKa = 4.43DD221 pKa = 3.87EE222 pKa = 5.02TVTGPNFPRR231 pKa = 11.84TYY233 pKa = 9.95RR234 pKa = 11.84IAVDD238 pKa = 3.27IPVGQTITNLTVTDD252 pKa = 4.76LLPPNLAFLAVTSTSPGGAVVLDD275 pKa = 4.15QPATPGAQLPPNNDD289 pKa = 4.05LIVRR293 pKa = 11.84WASVTGGASDD303 pKa = 3.52TDD305 pKa = 3.72VVVEE309 pKa = 4.7FTFYY313 pKa = 11.4VPLNDD318 pKa = 4.02ASGNPVLNPITGDD331 pKa = 3.67DD332 pKa = 3.83VLSLNDD338 pKa = 3.95SRR340 pKa = 11.84AEE342 pKa = 4.26GNWTPLDD349 pKa = 3.91PRR351 pKa = 11.84DD352 pKa = 3.52TAGLVTSNMPPSDD365 pKa = 3.49YY366 pKa = 10.88TITLKK371 pKa = 10.91SIAIQKK377 pKa = 9.88SVANLSPAPLSPGDD391 pKa = 3.61TLEE394 pKa = 4.07YY395 pKa = 9.41TLQVQVSDD403 pKa = 4.92FFALTDD409 pKa = 4.6IIIDD413 pKa = 4.0DD414 pKa = 4.68LFSDD418 pKa = 4.49GQAWDD423 pKa = 3.5ATFTPTLSVTEE434 pKa = 4.64HH435 pKa = 6.72GATTSAPMNSANYY448 pKa = 8.67TVIPNAFLGFTEE460 pKa = 4.16VTFRR464 pKa = 11.84VSSEE468 pKa = 3.91LQSRR472 pKa = 11.84GLDD475 pKa = 3.47RR476 pKa = 11.84ILLGGCVPDD485 pKa = 4.77GGTGGPVPDD494 pKa = 4.23CGAYY498 pKa = 10.25NGGATTLTLRR508 pKa = 11.84FRR510 pKa = 11.84TVVQEE515 pKa = 3.95NFLYY519 pKa = 10.28NYY521 pKa = 9.59PSGDD525 pKa = 3.51PSVDD529 pKa = 3.19QGDD532 pKa = 3.9MLNNLVTAMSNVLNVANLTPTGEE555 pKa = 4.43DD556 pKa = 3.48EE557 pKa = 4.29QDD559 pKa = 3.04SSQAEE564 pKa = 3.97TSIPRR569 pKa = 11.84GAGDD573 pKa = 3.3KK574 pKa = 10.18TIYY577 pKa = 10.31AINGVVCSPQPCTSVRR593 pKa = 11.84VAPADD598 pKa = 3.52TVTYY602 pKa = 10.02RR603 pKa = 11.84LRR605 pKa = 11.84YY606 pKa = 7.11TLPTSDD612 pKa = 4.19VEE614 pKa = 4.18NLYY617 pKa = 11.09LIDD620 pKa = 4.2YY621 pKa = 10.1LPLPVFNATEE631 pKa = 4.09VTTFNPTVSPAAPPAGQAKK650 pKa = 9.92FGPADD655 pKa = 3.18TFYY658 pKa = 10.67AYY660 pKa = 10.8SSLVPALTTSTAQNSVRR677 pKa = 11.84FDD679 pKa = 3.43YY680 pKa = 11.2GSYY683 pKa = 11.0DD684 pKa = 3.48SASNQSTTVDD694 pKa = 2.75ILFTVTVRR702 pKa = 11.84SDD704 pKa = 3.2PFADD708 pKa = 4.0GLYY711 pKa = 9.22LTNQLRR717 pKa = 11.84GHH719 pKa = 6.71EE720 pKa = 4.34GATNAGDD727 pKa = 3.79SVADD731 pKa = 4.06SIVQIQLTEE740 pKa = 4.75PILNIRR746 pKa = 11.84KK747 pKa = 8.97GVVWSEE753 pKa = 3.53NSAAVFNPSQVAPAGVTFSGSGCPRR778 pKa = 11.84FSGTVNSSGLATQPINSNITGGVDD802 pKa = 2.71AGDD805 pKa = 3.75RR806 pKa = 11.84LTFAITVEE814 pKa = 4.27NTGSGLNGAFDD825 pKa = 3.79VRR827 pKa = 11.84IADD830 pKa = 3.94TLPAGMTYY838 pKa = 10.51VPGSLCVTDD847 pKa = 3.86GTGAAIGYY855 pKa = 9.5SGAEE859 pKa = 3.69TDD861 pKa = 4.32LFGTGIVLNDD871 pKa = 4.58PGPTANPAGALDD883 pKa = 5.12PYY885 pKa = 10.6DD886 pKa = 3.92ASNGRR891 pKa = 11.84NIAVVTFDD899 pKa = 3.32VTLDD903 pKa = 3.51GTLVSGASLVNTALLTNYY921 pKa = 10.03AGSEE925 pKa = 4.17GGADD929 pKa = 3.52HH930 pKa = 7.11TPTDD934 pKa = 4.0LTDD937 pKa = 3.2QATVQARR944 pKa = 11.84TAGLGKK950 pKa = 10.14IFTTEE955 pKa = 4.07IINSVNSVTQAVIGEE970 pKa = 4.38LVTYY974 pKa = 7.15TVRR977 pKa = 11.84ITVPEE982 pKa = 3.94GVMNNVAVQDD992 pKa = 4.22DD993 pKa = 4.79LPAGLAFVDD1002 pKa = 4.33CLGITASTDD1011 pKa = 2.8VSTNLSGGFATACNDD1026 pKa = 4.34PINPTVNLNGHH1037 pKa = 4.95TVVFNLGTLTNANRR1051 pKa = 11.84DD1052 pKa = 3.51NSTDD1056 pKa = 3.47EE1057 pKa = 4.04YY1058 pKa = 11.65VDD1060 pKa = 3.24IQFTAVVLNEE1070 pKa = 4.68LGNQAGTTLRR1080 pKa = 11.84NTARR1084 pKa = 11.84LIVDD1088 pKa = 3.79GGAGGTATVQSADD1101 pKa = 3.53LTVIEE1106 pKa = 4.62PQVNTSKK1113 pKa = 10.76SASPNTNLDD1122 pKa = 3.39AGDD1125 pKa = 3.7VVTFTITLNNPNSAADD1141 pKa = 3.47TDD1143 pKa = 4.13AYY1145 pKa = 10.69DD1146 pKa = 3.86VVMTDD1151 pKa = 3.52VIPALFTYY1159 pKa = 10.45VPGSFTVSACSAGVPVLNDD1178 pKa = 3.29TALPTLTATFATFPRR1193 pKa = 11.84NTSCTLTFQATVNNTVRR1210 pKa = 11.84AGNPTVTNTATTTWTSLSGSPGDD1233 pKa = 3.25RR1234 pKa = 11.84SPYY1237 pKa = 7.84NTSSEE1242 pKa = 4.05EE1243 pKa = 4.07RR1244 pKa = 11.84DD1245 pKa = 3.74GSGAPLNDD1253 pKa = 3.6YY1254 pKa = 10.57LSSEE1258 pKa = 4.23PEE1260 pKa = 3.84PVNFANTATTKK1271 pKa = 10.75YY1272 pKa = 10.4LVATSEE1278 pKa = 4.19GHH1280 pKa = 5.18TSGASVAVGEE1290 pKa = 4.25IVRR1293 pKa = 11.84YY1294 pKa = 8.72RR1295 pKa = 11.84VVVRR1299 pKa = 11.84VPEE1302 pKa = 4.28GTQPNFQIRR1311 pKa = 11.84DD1312 pKa = 3.81NLPPGLTFLNDD1323 pKa = 3.45GTATLAFVSNGAGFTSTGIGIVPAIPAGCTVPGSTANATTPASPLPCTLADD1374 pKa = 3.86GNIGSTGSTATNLDD1388 pKa = 3.86NYY1390 pKa = 9.54TDD1392 pKa = 3.75AAGSFTGVDD1401 pKa = 3.68VYY1403 pKa = 10.95FKK1405 pKa = 11.02LGNLVNADD1413 pKa = 3.56SDD1415 pKa = 3.82PDD1417 pKa = 3.6YY1418 pKa = 10.27EE1419 pKa = 4.39YY1420 pKa = 11.75VVIEE1424 pKa = 4.38FNAFVDD1430 pKa = 3.81NNYY1433 pKa = 7.13PTNPNDD1439 pKa = 3.71TGDD1442 pKa = 3.59TRR1444 pKa = 11.84GNSANTYY1451 pKa = 10.47VNGSSNSTSNTVNVVVAEE1469 pKa = 4.02PLLTISKK1476 pKa = 7.65TASIASGDD1484 pKa = 3.65AGDD1487 pKa = 4.53PVTFTITVGAQSGANRR1503 pKa = 11.84TTAFDD1508 pKa = 4.09LVVSDD1513 pKa = 4.27TLDD1516 pKa = 3.72GYY1518 pKa = 10.52LVPGTVSVTSSQGATCAGGTPFNASASFAGQVMTMNATCLDD1559 pKa = 4.13PGQTITITIDD1569 pKa = 3.13ATISPSAPNGFSISNTATVTYY1590 pKa = 9.76TSLPGSGTPLGTSTIPGGDD1609 pKa = 3.41YY1610 pKa = 10.34YY1611 pKa = 11.24GEE1613 pKa = 4.26RR1614 pKa = 11.84NGTQTPNPNNDD1625 pKa = 2.76YY1626 pKa = 9.96RR1627 pKa = 11.84ASSTAIIVATNSPQIAKK1644 pKa = 9.94SVSPTTYY1651 pKa = 10.16TIGDD1655 pKa = 4.1LVTYY1659 pKa = 9.8NLVVTLPEE1667 pKa = 4.45GVTQALVVTDD1677 pKa = 5.71DD1678 pKa = 4.01IPAGLQVEE1686 pKa = 5.15SYY1688 pKa = 10.91QIITSAAASGGLLAADD1704 pKa = 3.86YY1705 pKa = 10.92NGALPAPTVTQAGGSGGDD1723 pKa = 3.03ITFNFGDD1730 pKa = 4.01TPTTADD1736 pKa = 3.11NVANNNAFLIQITARR1751 pKa = 11.84VLNIASNVDD1760 pKa = 3.06GTTLTNTATVAYY1772 pKa = 8.99NGPAVPPSSVNLTIIEE1788 pKa = 4.11PTIVTTKK1795 pKa = 10.82NVTPNANIQAGNLLTYY1811 pKa = 7.3TVRR1814 pKa = 11.84FTNTGNSPAYY1824 pKa = 10.32DD1825 pKa = 3.15ITAVDD1830 pKa = 3.76TLAQGVAYY1838 pKa = 10.26QSGSASCQFFDD1849 pKa = 5.03GVTTAPIAVNVTDD1862 pKa = 5.2AGATLTFSGVPADD1875 pKa = 4.02AWDD1878 pKa = 4.56LPVTDD1883 pKa = 4.22PDD1885 pKa = 4.06AYY1887 pKa = 9.88IEE1889 pKa = 4.2CTYY1892 pKa = 10.8QALALSSLHH1901 pKa = 7.16LDD1903 pKa = 3.68GAHH1906 pKa = 6.41VNTIDD1911 pKa = 5.48ADD1913 pKa = 3.71WSSHH1917 pKa = 5.2NGSDD1921 pKa = 3.44AFEE1924 pKa = 3.93RR1925 pKa = 11.84VYY1927 pKa = 11.36DD1928 pKa = 4.05DD1929 pKa = 3.32TTSYY1933 pKa = 11.14PNDD1936 pKa = 3.65GTQDD1940 pKa = 3.25TASATFTSPAPTFSKK1955 pKa = 10.88SDD1957 pKa = 3.34GGLTSATIGQVISYY1971 pKa = 7.98TLTMQSPLGTLRR1983 pKa = 11.84NLTITDD1989 pKa = 3.92TLPAGLIYY1997 pKa = 9.59QTGSLSVSAGITAPVSVTVSSPNDD2021 pKa = 3.18GTAPVTLTVDD2031 pKa = 4.04FGNAVVSSSPVTLTFTAQVANVAGNQQGISLNNTASLTYY2070 pKa = 10.12TDD2072 pKa = 3.33ATGTTRR2078 pKa = 11.84TLNASDD2084 pKa = 4.16PVTLVEE2090 pKa = 4.69PAMTLSKK2097 pKa = 10.75AVVPPTPADD2106 pKa = 3.38AGGVATYY2113 pKa = 9.83TLVLANPGGANVSPAYY2129 pKa = 9.81DD2130 pKa = 3.32VHH2132 pKa = 8.44LVDD2135 pKa = 4.72TLPAGLTLDD2144 pKa = 4.25LGSISVNLVGGAAGVTDD2161 pKa = 4.59ASAGNTVDD2169 pKa = 2.99ITIGVIPPGGSATVTFTATLDD2190 pKa = 3.86ANIQPGQTFNNTANADD2206 pKa = 3.5WTSLSGSVSGEE2217 pKa = 3.53RR2218 pKa = 11.84DD2219 pKa = 3.03GSGGVNDD2226 pKa = 4.06YY2227 pKa = 8.07RR2228 pKa = 11.84TSTSANFTSAGYY2240 pKa = 7.83TLSKK2244 pKa = 10.99ALVATSAGHH2253 pKa = 5.42TSGANLTIGEE2263 pKa = 4.6TVTFEE2268 pKa = 4.34LAVSLPEE2275 pKa = 4.02GTIPAPVVVTDD2286 pKa = 4.58DD2287 pKa = 4.23LPVGLAYY2294 pKa = 9.73VTGSGALDD2302 pKa = 3.14VTGFNGTVDD2311 pKa = 3.31STDD2314 pKa = 3.44PVITSAGGSGDD2325 pKa = 3.68DD2326 pKa = 4.09VVFTFNQPVVVNADD2340 pKa = 3.3NDD2342 pKa = 4.25PANNTLRR2349 pKa = 11.84LRR2351 pKa = 11.84LTARR2355 pKa = 11.84VVNEE2359 pKa = 4.0LANQNGVSLTNNASLQAGSGPVVQASPVTVTLVEE2393 pKa = 4.7PDD2395 pKa = 3.19LALNKK2400 pKa = 8.76TASTTTPGLGQVVTFTLTVAHH2421 pKa = 6.47SAASSADD2428 pKa = 3.46AQDD2431 pKa = 3.62VVLTDD2436 pKa = 4.05VIPAGLTYY2444 pKa = 10.76VPGSLASSGYY2454 pKa = 10.92APTVLDD2460 pKa = 5.43DD2461 pKa = 4.17SGAPNLLVRR2470 pKa = 11.84WDD2472 pKa = 3.97VLPLGQNGVITYY2484 pKa = 7.64QAQVTTPSLGTAMTNNAGLVWTSLSGSDD2512 pKa = 3.0SGEE2515 pKa = 3.7RR2516 pKa = 11.84DD2517 pKa = 3.04GSGGVNDD2524 pKa = 4.03YY2525 pKa = 11.12LRR2527 pKa = 11.84ASSVTLTSTGPDD2539 pKa = 3.44LQISKK2544 pKa = 10.63SDD2546 pKa = 3.41GGVSVIPGGTITYY2559 pKa = 7.58TLNYY2563 pKa = 10.0SNTGNGAATGVVISEE2578 pKa = 4.25TVPAHH2583 pKa = 4.62TTFVGPAGWTCTPNNNAGSVCTYY2606 pKa = 11.15NLGTLTPGASGSLTYY2621 pKa = 10.05QVQVVNPVPAGVTQINNVVYY2641 pKa = 10.32IADD2644 pKa = 4.97DD2645 pKa = 3.88GTHH2648 pKa = 6.68GNDD2651 pKa = 3.35PTPGNNTGSDD2661 pKa = 4.06DD2662 pKa = 4.12TPVDD2666 pKa = 3.83AVPDD2670 pKa = 3.78LTVSKK2675 pKa = 9.88TDD2677 pKa = 3.3GGVTAAPGDD2686 pKa = 3.81VVAYY2690 pKa = 7.4TISYY2694 pKa = 10.68ANVGNQAAEE2703 pKa = 4.03NVVLTEE2709 pKa = 4.03TVPANSVFNAGASTAGWNCTPDD2731 pKa = 3.4NNAGSTCTLSLGTLAGGASGTVTFAVTVDD2760 pKa = 3.4NPLPAGVTQIANTVVIADD2778 pKa = 4.53DD2779 pKa = 4.31GANGADD2785 pKa = 3.56PTPGNNTGSDD2795 pKa = 3.92DD2796 pKa = 4.25TPVDD2800 pKa = 3.65AAPDD2804 pKa = 3.68LTVSKK2809 pKa = 9.87TDD2811 pKa = 3.3GGVTAAPGDD2820 pKa = 3.81VVAYY2824 pKa = 7.4TISYY2828 pKa = 10.68ANVGNQAAEE2837 pKa = 4.03NVVLTEE2843 pKa = 4.03TVPANSVFNAGASTAGWNCTPDD2865 pKa = 3.4NNAGSTCTLSLGTLAGGASGTVTFAVTVDD2894 pKa = 3.4NPLPAGVTQIANTVVIADD2912 pKa = 4.53DD2913 pKa = 4.31GANGADD2919 pKa = 3.56PTPGNNTGSDD2929 pKa = 3.92DD2930 pKa = 4.25TPVDD2934 pKa = 3.65AAPDD2938 pKa = 3.68LTVSKK2943 pKa = 9.87TDD2945 pKa = 3.3GGVTAAPGDD2954 pKa = 3.81VVAYY2958 pKa = 7.4TISYY2962 pKa = 10.68ANVGNQAAEE2971 pKa = 4.03NVVLTEE2977 pKa = 4.03TVPANSVFNAGASTTGWNCTPDD2999 pKa = 3.47NNAGSTCTLSLGTLAGGASGTVTFAVTVDD3028 pKa = 3.4NPLPAGVTQIANTVVIADD3046 pKa = 4.53DD3047 pKa = 4.31GANGADD3053 pKa = 3.56PTPGNNTGSDD3063 pKa = 3.92DD3064 pKa = 4.25TPVDD3068 pKa = 3.65AAPDD3072 pKa = 3.68LTVSKK3077 pKa = 9.87TDD3079 pKa = 3.3GGVTAAPGDD3088 pKa = 3.81VVAYY3092 pKa = 7.4TISYY3096 pKa = 10.68ANVGNQAAEE3105 pKa = 4.03NVVLTEE3111 pKa = 4.03TVPANSVFNAGASTVGWSCVPDD3133 pKa = 3.63NNAGSTCTLSLGTLAGGASGTVTFAVTVDD3162 pKa = 3.4NPLPAGVTQIANTVVIADD3180 pKa = 4.69DD3181 pKa = 4.11GTNGADD3187 pKa = 3.34PTPGNNTGSDD3197 pKa = 3.88DD3198 pKa = 4.21TPLGAAPDD3206 pKa = 3.79LTIEE3210 pKa = 4.4KK3211 pKa = 10.2SDD3213 pKa = 3.56GVDD3216 pKa = 3.2LVSPGEE3222 pKa = 4.13TLVYY3226 pKa = 9.73TLTVRR3231 pKa = 11.84NVGNQEE3237 pKa = 3.6ATGVVVEE3244 pKa = 4.32EE3245 pKa = 4.44TVPSGTTFVSASSTSGWTCVPDD3267 pKa = 3.68NNAGSTCTLSLGSLAAGATVTVQFAVAVDD3296 pKa = 4.34DD3297 pKa = 4.9PLTPDD3302 pKa = 3.79ILNILNTVTVRR3313 pKa = 11.84DD3314 pKa = 4.26DD3315 pKa = 3.96GQNGADD3321 pKa = 3.74PTPDD3325 pKa = 3.51NNTSTDD3331 pKa = 3.03MDD3333 pKa = 4.66EE3334 pKa = 4.97IGVSAKK3340 pKa = 10.34QLVATNQDD3348 pKa = 2.99FTANPEE3354 pKa = 4.03VAIGEE3359 pKa = 4.33VLTYY3363 pKa = 9.96EE3364 pKa = 4.02ISLDD3368 pKa = 3.67VPAGSVQNLVLTDD3381 pKa = 3.45TLDD3384 pKa = 3.5RR3385 pKa = 11.84GLAFIGCDD3393 pKa = 4.25SITADD3398 pKa = 3.67PAVTASAGPLTAICNTASIAAEE3420 pKa = 4.02PAGSTNPADD3429 pKa = 4.49AGRR3432 pKa = 11.84KK3433 pKa = 5.0MTLNFGNVTNTSPEE3447 pKa = 3.91PQTLVVRR3454 pKa = 11.84YY3455 pKa = 8.97RR3456 pKa = 11.84VVVLDD3461 pKa = 3.37VAEE3464 pKa = 4.28NVSGVTLNNHH3474 pKa = 6.16AQWTWTGGNVEE3485 pKa = 4.58AEE3487 pKa = 3.96ASLVRR3492 pKa = 11.84IIEE3495 pKa = 3.94PRR3497 pKa = 11.84LMVEE3501 pKa = 3.79KK3502 pKa = 9.94TVAPRR3507 pKa = 11.84EE3508 pKa = 4.14AMEE3511 pKa = 4.33GQEE3514 pKa = 3.98VTFTITLSRR3523 pKa = 11.84HH3524 pKa = 5.97PDD3526 pKa = 3.4SEE3528 pKa = 4.79GPAHH3532 pKa = 6.42NVVLTDD3538 pKa = 3.26VVPYY3542 pKa = 10.65GLTYY3546 pKa = 10.81VPGSWQFVSGVAPTTLVEE3564 pKa = 4.44SGVPTLTATWDD3575 pKa = 3.62VFPANAPATVLQFRR3589 pKa = 11.84ARR3591 pKa = 11.84VTNIKK3596 pKa = 9.84PGSSVTNVAQVVWSSLPDD3614 pKa = 3.5YY3615 pKa = 10.95VGAPQSPYY3623 pKa = 10.07NPRR3626 pKa = 11.84SIEE3629 pKa = 3.73RR3630 pKa = 11.84SYY3632 pKa = 11.82VPGSVVDD3639 pKa = 3.82VYY3641 pKa = 11.15GASGKK3646 pKa = 10.58ASLLVPEE3653 pKa = 5.3LEE3655 pKa = 4.18LPKK3658 pKa = 10.59TGFAPGLVTQLPAQPADD3675 pKa = 3.42KK3676 pKa = 10.65QYY3678 pKa = 10.4TDD3680 pKa = 2.75QGMTLEE3686 pKa = 4.5IPTLGVKK3693 pKa = 10.19APIMGVPLTAEE3704 pKa = 4.18GWDD3707 pKa = 3.82LTWLSNQVGYY3717 pKa = 11.17LEE3719 pKa = 4.76GTAFPTWKK3727 pKa = 10.38GNSGLTAHH3735 pKa = 7.01VYY3737 pKa = 10.84GPDD3740 pKa = 3.54GKK3742 pKa = 9.82PGPFVNLGKK3751 pKa = 10.63LKK3753 pKa = 10.2WGDD3756 pKa = 3.69TIIIRR3761 pKa = 11.84YY3762 pKa = 8.79AGQEE3766 pKa = 3.33YY3767 pKa = 9.45RR3768 pKa = 11.84YY3769 pKa = 9.86AVRR3772 pKa = 11.84VVKK3775 pKa = 10.52RR3776 pKa = 11.84VQPDD3780 pKa = 3.43DD3781 pKa = 4.56LSVLGHH3787 pKa = 6.15QEE3789 pKa = 4.17RR3790 pKa = 11.84AWLTLITCQGYY3801 pKa = 8.04NQQTNDD3807 pKa = 3.09YY3808 pKa = 8.93ASRR3811 pKa = 11.84VVVQAVLIEE3820 pKa = 4.34VKK3822 pKa = 10.63
MM1 pKa = 7.32HH2 pKa = 7.51KK3 pKa = 10.41SVALRR8 pKa = 11.84IGSIWGIFLMLIGALPIVPVQARR31 pKa = 11.84PLAQPTTDD39 pKa = 2.73VSLNVPAEE47 pKa = 4.22TMLGQPFTFTVTFDD61 pKa = 3.95NNGTAPGYY69 pKa = 11.02GPFIDD74 pKa = 6.14LILPATGADD83 pKa = 3.73GDD85 pKa = 4.76DD86 pKa = 3.47GLTFAGATYY95 pKa = 10.66LGLPLSSVVLTFPAPTGCVAHH116 pKa = 7.12PYY118 pKa = 10.71AVDD121 pKa = 3.31TSGAPVQVCGTPGDD135 pKa = 3.78QLVVLLLPFGSFFPDD150 pKa = 3.36QPPVEE155 pKa = 4.51VNVSVNMNNYY165 pKa = 10.25ADD167 pKa = 3.88VDD169 pKa = 4.12TPLTIQARR177 pKa = 11.84GGYY180 pKa = 8.81QFGEE184 pKa = 4.68TPVSDD189 pKa = 4.2PSTDD193 pKa = 3.39PSIVGGWTTASTTPTLIRR211 pKa = 11.84VVKK214 pKa = 9.5TYY216 pKa = 10.61LGPEE220 pKa = 4.43DD221 pKa = 3.87EE222 pKa = 5.02TVTGPNFPRR231 pKa = 11.84TYY233 pKa = 9.95RR234 pKa = 11.84IAVDD238 pKa = 3.27IPVGQTITNLTVTDD252 pKa = 4.76LLPPNLAFLAVTSTSPGGAVVLDD275 pKa = 4.15QPATPGAQLPPNNDD289 pKa = 4.05LIVRR293 pKa = 11.84WASVTGGASDD303 pKa = 3.52TDD305 pKa = 3.72VVVEE309 pKa = 4.7FTFYY313 pKa = 11.4VPLNDD318 pKa = 4.02ASGNPVLNPITGDD331 pKa = 3.67DD332 pKa = 3.83VLSLNDD338 pKa = 3.95SRR340 pKa = 11.84AEE342 pKa = 4.26GNWTPLDD349 pKa = 3.91PRR351 pKa = 11.84DD352 pKa = 3.52TAGLVTSNMPPSDD365 pKa = 3.49YY366 pKa = 10.88TITLKK371 pKa = 10.91SIAIQKK377 pKa = 9.88SVANLSPAPLSPGDD391 pKa = 3.61TLEE394 pKa = 4.07YY395 pKa = 9.41TLQVQVSDD403 pKa = 4.92FFALTDD409 pKa = 4.6IIIDD413 pKa = 4.0DD414 pKa = 4.68LFSDD418 pKa = 4.49GQAWDD423 pKa = 3.5ATFTPTLSVTEE434 pKa = 4.64HH435 pKa = 6.72GATTSAPMNSANYY448 pKa = 8.67TVIPNAFLGFTEE460 pKa = 4.16VTFRR464 pKa = 11.84VSSEE468 pKa = 3.91LQSRR472 pKa = 11.84GLDD475 pKa = 3.47RR476 pKa = 11.84ILLGGCVPDD485 pKa = 4.77GGTGGPVPDD494 pKa = 4.23CGAYY498 pKa = 10.25NGGATTLTLRR508 pKa = 11.84FRR510 pKa = 11.84TVVQEE515 pKa = 3.95NFLYY519 pKa = 10.28NYY521 pKa = 9.59PSGDD525 pKa = 3.51PSVDD529 pKa = 3.19QGDD532 pKa = 3.9MLNNLVTAMSNVLNVANLTPTGEE555 pKa = 4.43DD556 pKa = 3.48EE557 pKa = 4.29QDD559 pKa = 3.04SSQAEE564 pKa = 3.97TSIPRR569 pKa = 11.84GAGDD573 pKa = 3.3KK574 pKa = 10.18TIYY577 pKa = 10.31AINGVVCSPQPCTSVRR593 pKa = 11.84VAPADD598 pKa = 3.52TVTYY602 pKa = 10.02RR603 pKa = 11.84LRR605 pKa = 11.84YY606 pKa = 7.11TLPTSDD612 pKa = 4.19VEE614 pKa = 4.18NLYY617 pKa = 11.09LIDD620 pKa = 4.2YY621 pKa = 10.1LPLPVFNATEE631 pKa = 4.09VTTFNPTVSPAAPPAGQAKK650 pKa = 9.92FGPADD655 pKa = 3.18TFYY658 pKa = 10.67AYY660 pKa = 10.8SSLVPALTTSTAQNSVRR677 pKa = 11.84FDD679 pKa = 3.43YY680 pKa = 11.2GSYY683 pKa = 11.0DD684 pKa = 3.48SASNQSTTVDD694 pKa = 2.75ILFTVTVRR702 pKa = 11.84SDD704 pKa = 3.2PFADD708 pKa = 4.0GLYY711 pKa = 9.22LTNQLRR717 pKa = 11.84GHH719 pKa = 6.71EE720 pKa = 4.34GATNAGDD727 pKa = 3.79SVADD731 pKa = 4.06SIVQIQLTEE740 pKa = 4.75PILNIRR746 pKa = 11.84KK747 pKa = 8.97GVVWSEE753 pKa = 3.53NSAAVFNPSQVAPAGVTFSGSGCPRR778 pKa = 11.84FSGTVNSSGLATQPINSNITGGVDD802 pKa = 2.71AGDD805 pKa = 3.75RR806 pKa = 11.84LTFAITVEE814 pKa = 4.27NTGSGLNGAFDD825 pKa = 3.79VRR827 pKa = 11.84IADD830 pKa = 3.94TLPAGMTYY838 pKa = 10.51VPGSLCVTDD847 pKa = 3.86GTGAAIGYY855 pKa = 9.5SGAEE859 pKa = 3.69TDD861 pKa = 4.32LFGTGIVLNDD871 pKa = 4.58PGPTANPAGALDD883 pKa = 5.12PYY885 pKa = 10.6DD886 pKa = 3.92ASNGRR891 pKa = 11.84NIAVVTFDD899 pKa = 3.32VTLDD903 pKa = 3.51GTLVSGASLVNTALLTNYY921 pKa = 10.03AGSEE925 pKa = 4.17GGADD929 pKa = 3.52HH930 pKa = 7.11TPTDD934 pKa = 4.0LTDD937 pKa = 3.2QATVQARR944 pKa = 11.84TAGLGKK950 pKa = 10.14IFTTEE955 pKa = 4.07IINSVNSVTQAVIGEE970 pKa = 4.38LVTYY974 pKa = 7.15TVRR977 pKa = 11.84ITVPEE982 pKa = 3.94GVMNNVAVQDD992 pKa = 4.22DD993 pKa = 4.79LPAGLAFVDD1002 pKa = 4.33CLGITASTDD1011 pKa = 2.8VSTNLSGGFATACNDD1026 pKa = 4.34PINPTVNLNGHH1037 pKa = 4.95TVVFNLGTLTNANRR1051 pKa = 11.84DD1052 pKa = 3.51NSTDD1056 pKa = 3.47EE1057 pKa = 4.04YY1058 pKa = 11.65VDD1060 pKa = 3.24IQFTAVVLNEE1070 pKa = 4.68LGNQAGTTLRR1080 pKa = 11.84NTARR1084 pKa = 11.84LIVDD1088 pKa = 3.79GGAGGTATVQSADD1101 pKa = 3.53LTVIEE1106 pKa = 4.62PQVNTSKK1113 pKa = 10.76SASPNTNLDD1122 pKa = 3.39AGDD1125 pKa = 3.7VVTFTITLNNPNSAADD1141 pKa = 3.47TDD1143 pKa = 4.13AYY1145 pKa = 10.69DD1146 pKa = 3.86VVMTDD1151 pKa = 3.52VIPALFTYY1159 pKa = 10.45VPGSFTVSACSAGVPVLNDD1178 pKa = 3.29TALPTLTATFATFPRR1193 pKa = 11.84NTSCTLTFQATVNNTVRR1210 pKa = 11.84AGNPTVTNTATTTWTSLSGSPGDD1233 pKa = 3.25RR1234 pKa = 11.84SPYY1237 pKa = 7.84NTSSEE1242 pKa = 4.05EE1243 pKa = 4.07RR1244 pKa = 11.84DD1245 pKa = 3.74GSGAPLNDD1253 pKa = 3.6YY1254 pKa = 10.57LSSEE1258 pKa = 4.23PEE1260 pKa = 3.84PVNFANTATTKK1271 pKa = 10.75YY1272 pKa = 10.4LVATSEE1278 pKa = 4.19GHH1280 pKa = 5.18TSGASVAVGEE1290 pKa = 4.25IVRR1293 pKa = 11.84YY1294 pKa = 8.72RR1295 pKa = 11.84VVVRR1299 pKa = 11.84VPEE1302 pKa = 4.28GTQPNFQIRR1311 pKa = 11.84DD1312 pKa = 3.81NLPPGLTFLNDD1323 pKa = 3.45GTATLAFVSNGAGFTSTGIGIVPAIPAGCTVPGSTANATTPASPLPCTLADD1374 pKa = 3.86GNIGSTGSTATNLDD1388 pKa = 3.86NYY1390 pKa = 9.54TDD1392 pKa = 3.75AAGSFTGVDD1401 pKa = 3.68VYY1403 pKa = 10.95FKK1405 pKa = 11.02LGNLVNADD1413 pKa = 3.56SDD1415 pKa = 3.82PDD1417 pKa = 3.6YY1418 pKa = 10.27EE1419 pKa = 4.39YY1420 pKa = 11.75VVIEE1424 pKa = 4.38FNAFVDD1430 pKa = 3.81NNYY1433 pKa = 7.13PTNPNDD1439 pKa = 3.71TGDD1442 pKa = 3.59TRR1444 pKa = 11.84GNSANTYY1451 pKa = 10.47VNGSSNSTSNTVNVVVAEE1469 pKa = 4.02PLLTISKK1476 pKa = 7.65TASIASGDD1484 pKa = 3.65AGDD1487 pKa = 4.53PVTFTITVGAQSGANRR1503 pKa = 11.84TTAFDD1508 pKa = 4.09LVVSDD1513 pKa = 4.27TLDD1516 pKa = 3.72GYY1518 pKa = 10.52LVPGTVSVTSSQGATCAGGTPFNASASFAGQVMTMNATCLDD1559 pKa = 4.13PGQTITITIDD1569 pKa = 3.13ATISPSAPNGFSISNTATVTYY1590 pKa = 9.76TSLPGSGTPLGTSTIPGGDD1609 pKa = 3.41YY1610 pKa = 10.34YY1611 pKa = 11.24GEE1613 pKa = 4.26RR1614 pKa = 11.84NGTQTPNPNNDD1625 pKa = 2.76YY1626 pKa = 9.96RR1627 pKa = 11.84ASSTAIIVATNSPQIAKK1644 pKa = 9.94SVSPTTYY1651 pKa = 10.16TIGDD1655 pKa = 4.1LVTYY1659 pKa = 9.8NLVVTLPEE1667 pKa = 4.45GVTQALVVTDD1677 pKa = 5.71DD1678 pKa = 4.01IPAGLQVEE1686 pKa = 5.15SYY1688 pKa = 10.91QIITSAAASGGLLAADD1704 pKa = 3.86YY1705 pKa = 10.92NGALPAPTVTQAGGSGGDD1723 pKa = 3.03ITFNFGDD1730 pKa = 4.01TPTTADD1736 pKa = 3.11NVANNNAFLIQITARR1751 pKa = 11.84VLNIASNVDD1760 pKa = 3.06GTTLTNTATVAYY1772 pKa = 8.99NGPAVPPSSVNLTIIEE1788 pKa = 4.11PTIVTTKK1795 pKa = 10.82NVTPNANIQAGNLLTYY1811 pKa = 7.3TVRR1814 pKa = 11.84FTNTGNSPAYY1824 pKa = 10.32DD1825 pKa = 3.15ITAVDD1830 pKa = 3.76TLAQGVAYY1838 pKa = 10.26QSGSASCQFFDD1849 pKa = 5.03GVTTAPIAVNVTDD1862 pKa = 5.2AGATLTFSGVPADD1875 pKa = 4.02AWDD1878 pKa = 4.56LPVTDD1883 pKa = 4.22PDD1885 pKa = 4.06AYY1887 pKa = 9.88IEE1889 pKa = 4.2CTYY1892 pKa = 10.8QALALSSLHH1901 pKa = 7.16LDD1903 pKa = 3.68GAHH1906 pKa = 6.41VNTIDD1911 pKa = 5.48ADD1913 pKa = 3.71WSSHH1917 pKa = 5.2NGSDD1921 pKa = 3.44AFEE1924 pKa = 3.93RR1925 pKa = 11.84VYY1927 pKa = 11.36DD1928 pKa = 4.05DD1929 pKa = 3.32TTSYY1933 pKa = 11.14PNDD1936 pKa = 3.65GTQDD1940 pKa = 3.25TASATFTSPAPTFSKK1955 pKa = 10.88SDD1957 pKa = 3.34GGLTSATIGQVISYY1971 pKa = 7.98TLTMQSPLGTLRR1983 pKa = 11.84NLTITDD1989 pKa = 3.92TLPAGLIYY1997 pKa = 9.59QTGSLSVSAGITAPVSVTVSSPNDD2021 pKa = 3.18GTAPVTLTVDD2031 pKa = 4.04FGNAVVSSSPVTLTFTAQVANVAGNQQGISLNNTASLTYY2070 pKa = 10.12TDD2072 pKa = 3.33ATGTTRR2078 pKa = 11.84TLNASDD2084 pKa = 4.16PVTLVEE2090 pKa = 4.69PAMTLSKK2097 pKa = 10.75AVVPPTPADD2106 pKa = 3.38AGGVATYY2113 pKa = 9.83TLVLANPGGANVSPAYY2129 pKa = 9.81DD2130 pKa = 3.32VHH2132 pKa = 8.44LVDD2135 pKa = 4.72TLPAGLTLDD2144 pKa = 4.25LGSISVNLVGGAAGVTDD2161 pKa = 4.59ASAGNTVDD2169 pKa = 2.99ITIGVIPPGGSATVTFTATLDD2190 pKa = 3.86ANIQPGQTFNNTANADD2206 pKa = 3.5WTSLSGSVSGEE2217 pKa = 3.53RR2218 pKa = 11.84DD2219 pKa = 3.03GSGGVNDD2226 pKa = 4.06YY2227 pKa = 8.07RR2228 pKa = 11.84TSTSANFTSAGYY2240 pKa = 7.83TLSKK2244 pKa = 10.99ALVATSAGHH2253 pKa = 5.42TSGANLTIGEE2263 pKa = 4.6TVTFEE2268 pKa = 4.34LAVSLPEE2275 pKa = 4.02GTIPAPVVVTDD2286 pKa = 4.58DD2287 pKa = 4.23LPVGLAYY2294 pKa = 9.73VTGSGALDD2302 pKa = 3.14VTGFNGTVDD2311 pKa = 3.31STDD2314 pKa = 3.44PVITSAGGSGDD2325 pKa = 3.68DD2326 pKa = 4.09VVFTFNQPVVVNADD2340 pKa = 3.3NDD2342 pKa = 4.25PANNTLRR2349 pKa = 11.84LRR2351 pKa = 11.84LTARR2355 pKa = 11.84VVNEE2359 pKa = 4.0LANQNGVSLTNNASLQAGSGPVVQASPVTVTLVEE2393 pKa = 4.7PDD2395 pKa = 3.19LALNKK2400 pKa = 8.76TASTTTPGLGQVVTFTLTVAHH2421 pKa = 6.47SAASSADD2428 pKa = 3.46AQDD2431 pKa = 3.62VVLTDD2436 pKa = 4.05VIPAGLTYY2444 pKa = 10.76VPGSLASSGYY2454 pKa = 10.92APTVLDD2460 pKa = 5.43DD2461 pKa = 4.17SGAPNLLVRR2470 pKa = 11.84WDD2472 pKa = 3.97VLPLGQNGVITYY2484 pKa = 7.64QAQVTTPSLGTAMTNNAGLVWTSLSGSDD2512 pKa = 3.0SGEE2515 pKa = 3.7RR2516 pKa = 11.84DD2517 pKa = 3.04GSGGVNDD2524 pKa = 4.03YY2525 pKa = 11.12LRR2527 pKa = 11.84ASSVTLTSTGPDD2539 pKa = 3.44LQISKK2544 pKa = 10.63SDD2546 pKa = 3.41GGVSVIPGGTITYY2559 pKa = 7.58TLNYY2563 pKa = 10.0SNTGNGAATGVVISEE2578 pKa = 4.25TVPAHH2583 pKa = 4.62TTFVGPAGWTCTPNNNAGSVCTYY2606 pKa = 11.15NLGTLTPGASGSLTYY2621 pKa = 10.05QVQVVNPVPAGVTQINNVVYY2641 pKa = 10.32IADD2644 pKa = 4.97DD2645 pKa = 3.88GTHH2648 pKa = 6.68GNDD2651 pKa = 3.35PTPGNNTGSDD2661 pKa = 4.06DD2662 pKa = 4.12TPVDD2666 pKa = 3.83AVPDD2670 pKa = 3.78LTVSKK2675 pKa = 9.88TDD2677 pKa = 3.3GGVTAAPGDD2686 pKa = 3.81VVAYY2690 pKa = 7.4TISYY2694 pKa = 10.68ANVGNQAAEE2703 pKa = 4.03NVVLTEE2709 pKa = 4.03TVPANSVFNAGASTAGWNCTPDD2731 pKa = 3.4NNAGSTCTLSLGTLAGGASGTVTFAVTVDD2760 pKa = 3.4NPLPAGVTQIANTVVIADD2778 pKa = 4.53DD2779 pKa = 4.31GANGADD2785 pKa = 3.56PTPGNNTGSDD2795 pKa = 3.92DD2796 pKa = 4.25TPVDD2800 pKa = 3.65AAPDD2804 pKa = 3.68LTVSKK2809 pKa = 9.87TDD2811 pKa = 3.3GGVTAAPGDD2820 pKa = 3.81VVAYY2824 pKa = 7.4TISYY2828 pKa = 10.68ANVGNQAAEE2837 pKa = 4.03NVVLTEE2843 pKa = 4.03TVPANSVFNAGASTAGWNCTPDD2865 pKa = 3.4NNAGSTCTLSLGTLAGGASGTVTFAVTVDD2894 pKa = 3.4NPLPAGVTQIANTVVIADD2912 pKa = 4.53DD2913 pKa = 4.31GANGADD2919 pKa = 3.56PTPGNNTGSDD2929 pKa = 3.92DD2930 pKa = 4.25TPVDD2934 pKa = 3.65AAPDD2938 pKa = 3.68LTVSKK2943 pKa = 9.87TDD2945 pKa = 3.3GGVTAAPGDD2954 pKa = 3.81VVAYY2958 pKa = 7.4TISYY2962 pKa = 10.68ANVGNQAAEE2971 pKa = 4.03NVVLTEE2977 pKa = 4.03TVPANSVFNAGASTTGWNCTPDD2999 pKa = 3.47NNAGSTCTLSLGTLAGGASGTVTFAVTVDD3028 pKa = 3.4NPLPAGVTQIANTVVIADD3046 pKa = 4.53DD3047 pKa = 4.31GANGADD3053 pKa = 3.56PTPGNNTGSDD3063 pKa = 3.92DD3064 pKa = 4.25TPVDD3068 pKa = 3.65AAPDD3072 pKa = 3.68LTVSKK3077 pKa = 9.87TDD3079 pKa = 3.3GGVTAAPGDD3088 pKa = 3.81VVAYY3092 pKa = 7.4TISYY3096 pKa = 10.68ANVGNQAAEE3105 pKa = 4.03NVVLTEE3111 pKa = 4.03TVPANSVFNAGASTVGWSCVPDD3133 pKa = 3.63NNAGSTCTLSLGTLAGGASGTVTFAVTVDD3162 pKa = 3.4NPLPAGVTQIANTVVIADD3180 pKa = 4.69DD3181 pKa = 4.11GTNGADD3187 pKa = 3.34PTPGNNTGSDD3197 pKa = 3.88DD3198 pKa = 4.21TPLGAAPDD3206 pKa = 3.79LTIEE3210 pKa = 4.4KK3211 pKa = 10.2SDD3213 pKa = 3.56GVDD3216 pKa = 3.2LVSPGEE3222 pKa = 4.13TLVYY3226 pKa = 9.73TLTVRR3231 pKa = 11.84NVGNQEE3237 pKa = 3.6ATGVVVEE3244 pKa = 4.32EE3245 pKa = 4.44TVPSGTTFVSASSTSGWTCVPDD3267 pKa = 3.68NNAGSTCTLSLGSLAAGATVTVQFAVAVDD3296 pKa = 4.34DD3297 pKa = 4.9PLTPDD3302 pKa = 3.79ILNILNTVTVRR3313 pKa = 11.84DD3314 pKa = 4.26DD3315 pKa = 3.96GQNGADD3321 pKa = 3.74PTPDD3325 pKa = 3.51NNTSTDD3331 pKa = 3.03MDD3333 pKa = 4.66EE3334 pKa = 4.97IGVSAKK3340 pKa = 10.34QLVATNQDD3348 pKa = 2.99FTANPEE3354 pKa = 4.03VAIGEE3359 pKa = 4.33VLTYY3363 pKa = 9.96EE3364 pKa = 4.02ISLDD3368 pKa = 3.67VPAGSVQNLVLTDD3381 pKa = 3.45TLDD3384 pKa = 3.5RR3385 pKa = 11.84GLAFIGCDD3393 pKa = 4.25SITADD3398 pKa = 3.67PAVTASAGPLTAICNTASIAAEE3420 pKa = 4.02PAGSTNPADD3429 pKa = 4.49AGRR3432 pKa = 11.84KK3433 pKa = 5.0MTLNFGNVTNTSPEE3447 pKa = 3.91PQTLVVRR3454 pKa = 11.84YY3455 pKa = 8.97RR3456 pKa = 11.84VVVLDD3461 pKa = 3.37VAEE3464 pKa = 4.28NVSGVTLNNHH3474 pKa = 6.16AQWTWTGGNVEE3485 pKa = 4.58AEE3487 pKa = 3.96ASLVRR3492 pKa = 11.84IIEE3495 pKa = 3.94PRR3497 pKa = 11.84LMVEE3501 pKa = 3.79KK3502 pKa = 9.94TVAPRR3507 pKa = 11.84EE3508 pKa = 4.14AMEE3511 pKa = 4.33GQEE3514 pKa = 3.98VTFTITLSRR3523 pKa = 11.84HH3524 pKa = 5.97PDD3526 pKa = 3.4SEE3528 pKa = 4.79GPAHH3532 pKa = 6.42NVVLTDD3538 pKa = 3.26VVPYY3542 pKa = 10.65GLTYY3546 pKa = 10.81VPGSWQFVSGVAPTTLVEE3564 pKa = 4.44SGVPTLTATWDD3575 pKa = 3.62VFPANAPATVLQFRR3589 pKa = 11.84ARR3591 pKa = 11.84VTNIKK3596 pKa = 9.84PGSSVTNVAQVVWSSLPDD3614 pKa = 3.5YY3615 pKa = 10.95VGAPQSPYY3623 pKa = 10.07NPRR3626 pKa = 11.84SIEE3629 pKa = 3.73RR3630 pKa = 11.84SYY3632 pKa = 11.82VPGSVVDD3639 pKa = 3.82VYY3641 pKa = 11.15GASGKK3646 pKa = 10.58ASLLVPEE3653 pKa = 5.3LEE3655 pKa = 4.18LPKK3658 pKa = 10.59TGFAPGLVTQLPAQPADD3675 pKa = 3.42KK3676 pKa = 10.65QYY3678 pKa = 10.4TDD3680 pKa = 2.75QGMTLEE3686 pKa = 4.5IPTLGVKK3693 pKa = 10.19APIMGVPLTAEE3704 pKa = 4.18GWDD3707 pKa = 3.82LTWLSNQVGYY3717 pKa = 11.17LEE3719 pKa = 4.76GTAFPTWKK3727 pKa = 10.38GNSGLTAHH3735 pKa = 7.01VYY3737 pKa = 10.84GPDD3740 pKa = 3.54GKK3742 pKa = 9.82PGPFVNLGKK3751 pKa = 10.63LKK3753 pKa = 10.2WGDD3756 pKa = 3.69TIIIRR3761 pKa = 11.84YY3762 pKa = 8.79AGQEE3766 pKa = 3.33YY3767 pKa = 9.45RR3768 pKa = 11.84YY3769 pKa = 9.86AVRR3772 pKa = 11.84VVKK3775 pKa = 10.52RR3776 pKa = 11.84VQPDD3780 pKa = 3.43DD3781 pKa = 4.56LSVLGHH3787 pKa = 6.15QEE3789 pKa = 4.17RR3790 pKa = 11.84AWLTLITCQGYY3801 pKa = 8.04NQQTNDD3807 pKa = 3.09YY3808 pKa = 8.93ASRR3811 pKa = 11.84VVVQAVLIEE3820 pKa = 4.34VKK3822 pKa = 10.63
Molecular weight: 389.71 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>tr|E8MYH8|E8MYH8_ANATU Uncharacterized protein OS=Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1) OX=926569 GN=ANT_00890 PE=4 SV=1
MM1 pKa = 7.85DD2 pKa = 4.73LWNILSFMALGFTLGSIPFAYY23 pKa = 9.6ILARR27 pKa = 11.84VFTGRR32 pKa = 11.84DD33 pKa = 2.84VRR35 pKa = 11.84AIGDD39 pKa = 4.1GNPGAANAWKK49 pKa = 10.48AGGWRR54 pKa = 11.84IGLLAVFFDD63 pKa = 4.22LCKK66 pKa = 10.85GFLPLFLAQRR76 pKa = 11.84AGLSEE81 pKa = 3.96WALVPVALSPILGHH95 pKa = 7.12ALQPFLQFRR104 pKa = 11.84GGKK107 pKa = 9.34ALAVSGGVWLAWIGPRR123 pKa = 11.84VFPVYY128 pKa = 10.76ASLTLPVLALQEE140 pKa = 4.0EE141 pKa = 4.8HH142 pKa = 6.42AWAAFSGTLALLAYY156 pKa = 9.54ALWLGTSPALMVFAALNMVLIGWTHH181 pKa = 5.51RR182 pKa = 11.84RR183 pKa = 11.84EE184 pKa = 4.0LAHH187 pKa = 6.93APRR190 pKa = 11.84PRR192 pKa = 11.84AWVGHH197 pKa = 5.21LLSRR201 pKa = 11.84RR202 pKa = 11.84EE203 pKa = 3.9AA204 pKa = 3.56
MM1 pKa = 7.85DD2 pKa = 4.73LWNILSFMALGFTLGSIPFAYY23 pKa = 9.6ILARR27 pKa = 11.84VFTGRR32 pKa = 11.84DD33 pKa = 2.84VRR35 pKa = 11.84AIGDD39 pKa = 4.1GNPGAANAWKK49 pKa = 10.48AGGWRR54 pKa = 11.84IGLLAVFFDD63 pKa = 4.22LCKK66 pKa = 10.85GFLPLFLAQRR76 pKa = 11.84AGLSEE81 pKa = 3.96WALVPVALSPILGHH95 pKa = 7.12ALQPFLQFRR104 pKa = 11.84GGKK107 pKa = 9.34ALAVSGGVWLAWIGPRR123 pKa = 11.84VFPVYY128 pKa = 10.76ASLTLPVLALQEE140 pKa = 4.0EE141 pKa = 4.8HH142 pKa = 6.42AWAAFSGTLALLAYY156 pKa = 9.54ALWLGTSPALMVFAALNMVLIGWTHH181 pKa = 5.51RR182 pKa = 11.84RR183 pKa = 11.84EE184 pKa = 4.0LAHH187 pKa = 6.93APRR190 pKa = 11.84PRR192 pKa = 11.84AWVGHH197 pKa = 5.21LLSRR201 pKa = 11.84RR202 pKa = 11.84EE203 pKa = 3.9AA204 pKa = 3.56
Molecular weight: 22.16 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
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| ChTry ESI |
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| ArgC ESI |
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| LysN ESI |
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| TryLysC ESI |
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| Try MALDI |
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| ChTry MALDI |
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| ArgC MALDI |
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| LysN MALDI |
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| TryLysC MALDI |
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| Try LTQ |
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| ChTry LTQ |
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|---|
| ArgC LTQ |
|
|---|
| LysN LTQ |
|
|---|
| TryLysC LTQ |
|
|---|
| Try MSlow |
|
|---|
| ChTry MSlow |
|
|---|
| ArgC MSlow |
|
|---|
| LysN MSlow |
|
|---|
| TryLysC MSlow |
|
|---|
| Try MShigh |
|
|---|
| ChTry MShigh |
|
|---|
| ArgC MShigh |
|
|---|
| LysN MShigh |
|
|---|
| TryLysC MShigh |
|
|---|
General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
0 |
1070231 |
32 |
3822 |
344.1 |
38.3 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
9.091 ± 0.049 | 0.817 ± 0.013 |
4.433 ± 0.033 | 6.701 ± 0.05 |
4.14 ± 0.032 | 7.46 ± 0.041 |
2.039 ± 0.02 | 5.739 ± 0.041 |
3.51 ± 0.031 | 11.533 ± 0.061 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
2.383 ± 0.02 | 3.105 ± 0.026 |
5.575 ± 0.035 | 4.194 ± 0.029 |
6.426 ± 0.043 | 5.423 ± 0.028 |
5.273 ± 0.044 | 7.485 ± 0.038 |
1.695 ± 0.022 | 2.977 ± 0.025 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |