Gulo gulo (Wolverine) (Gluton)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Mustelida

Average proteome isoelectric point is 7.11

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 19667 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A3P4RSQ7|A0A3P4RSQ7_GULGU Isoform of A0A3P4NLQ4 Uncharacterized protein OS=Gulo gulo OX=48420 GN=BN2614_LOCUS1 PE=4 SV=1
MM1 pKa = 7.97DD2 pKa = 3.9VLFVAILAVQLILGQEE18 pKa = 4.25YY19 pKa = 10.31EE20 pKa = 4.25DD21 pKa = 4.2EE22 pKa = 4.59EE23 pKa = 4.67GLEE26 pKa = 4.09EE27 pKa = 4.86DD28 pKa = 5.18DD29 pKa = 4.61YY30 pKa = 11.18YY31 pKa = 11.46QVVYY35 pKa = 10.49YY36 pKa = 7.58YY37 pKa = 10.36TVTPNYY43 pKa = 10.56DD44 pKa = 3.23DD45 pKa = 4.83FGANFTVDD53 pKa = 3.11YY54 pKa = 11.54SMFEE58 pKa = 3.97SEE60 pKa = 5.5DD61 pKa = 3.28RR62 pKa = 11.84LNRR65 pKa = 11.84LDD67 pKa = 3.73KK68 pKa = 10.47EE69 pKa = 4.2VRR71 pKa = 11.84EE72 pKa = 4.17AAEE75 pKa = 4.06TTISHH80 pKa = 5.3EE81 pKa = 4.38TEE83 pKa = 4.08GADD86 pKa = 3.43TQKK89 pKa = 11.07PEE91 pKa = 4.21TVKK94 pKa = 10.79PMTTEE99 pKa = 3.86PQSPDD104 pKa = 3.21LNDD107 pKa = 3.7AVSSLQSPVPLLLSWALVQGGMYY130 pKa = 10.45FMM132 pKa = 6.15

Molecular weight: 15.02 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A3P4P5D4|A0A3P4P5D4_GULGU Isoform of A0A3P4LZP0 Uncharacterized protein OS=Gulo gulo OX=48420 GN=BN2614_LOCUS2 PE=4 SV=1
MM1 pKa = 7.86PGRR4 pKa = 11.84GRR6 pKa = 11.84GVYY9 pKa = 9.84GGRR12 pKa = 11.84AVRR15 pKa = 11.84AAAHH19 pKa = 6.3RR20 pKa = 11.84VRR22 pKa = 11.84GSVPGSGRR30 pKa = 11.84GRR32 pKa = 11.84RR33 pKa = 11.84LPPRR37 pKa = 11.84PLPPRR42 pKa = 11.84LAPLLRR48 pKa = 11.84PRR50 pKa = 11.84ASRR53 pKa = 11.84AHH55 pKa = 6.24PRR57 pKa = 11.84AALLPVRR64 pKa = 11.84HH65 pKa = 6.02RR66 pKa = 11.84SVRR69 pKa = 11.84RR70 pKa = 11.84APAPDD75 pKa = 3.37LRR77 pKa = 11.84ASLRR81 pKa = 11.84LRR83 pKa = 11.84GARR86 pKa = 11.84AGAAFLPRR94 pKa = 11.84TLRR97 pKa = 11.84RR98 pKa = 11.84LXXXXXXXAPPPGLPGLLLAGPQRR122 pKa = 11.84PRR124 pKa = 11.84RR125 pKa = 11.84LPAGG129 pKa = 3.57

Molecular weight: 13.06 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

23

19644

19667

6479575

8

8221

329.5

36.64

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.072 ± 0.021

2.266 ± 0.015

4.621 ± 0.013

6.848 ± 0.028

3.693 ± 0.016

6.673 ± 0.028

2.606 ± 0.01

4.283 ± 0.02

5.555 ± 0.025

10.068 ± 0.03

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.152 ± 0.009

3.478 ± 0.016

6.435 ± 0.031

4.651 ± 0.019

5.942 ± 0.019

8.32 ± 0.026

5.244 ± 0.017

6.051 ± 0.016

1.294 ± 0.007

2.588 ± 0.011
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski