Theileria parva (East coast fever infection agent)

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida; Theileriidae; Theileria

Average proteome isoelectric point is 6.76

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4071 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q4MZP6|Q4MZP6_THEPA Uncharacterized protein OS=Theileria parva OX=5875 GN=TP03_0471 PE=4 SV=1
MM1 pKa = 7.7SSTILNSINSLDD13 pKa = 3.58YY14 pKa = 10.85SLEE17 pKa = 4.04VEE19 pKa = 4.07SDD21 pKa = 3.65GNFGKK26 pKa = 8.72FTDD29 pKa = 3.54QLVYY33 pKa = 10.62EE34 pKa = 4.39VVKK37 pKa = 10.98LSEE40 pKa = 4.29CDD42 pKa = 3.48YY43 pKa = 11.44DD44 pKa = 4.36PEE46 pKa = 4.6TEE48 pKa = 4.07TFYY51 pKa = 11.22YY52 pKa = 10.62LCPCGDD58 pKa = 3.78LFEE61 pKa = 5.14IALEE65 pKa = 4.34DD66 pKa = 3.91LLKK69 pKa = 11.24GNLISEE75 pKa = 4.83CPSCSLRR82 pKa = 11.84IRR84 pKa = 11.84IDD86 pKa = 3.88LKK88 pKa = 11.07PGDD91 pKa = 4.28LDD93 pKa = 3.39QFVNMKK99 pKa = 8.9TVV101 pKa = 2.66

Molecular weight: 11.42 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q4N2T1|Q4N2T1_THEPA Small nuclear ribonucleoprotein putative OS=Theileria parva OX=5875 GN=TP04_0265 PE=3 SV=1
MM1 pKa = 7.74GMDD4 pKa = 4.12DD5 pKa = 5.05LSRR8 pKa = 11.84IYY10 pKa = 10.21IGNLPEE16 pKa = 5.1DD17 pKa = 3.93CSQRR21 pKa = 11.84EE22 pKa = 4.09LEE24 pKa = 4.23EE25 pKa = 3.98EE26 pKa = 4.05FEE28 pKa = 4.24KK29 pKa = 10.71FGRR32 pKa = 11.84IIYY35 pKa = 10.26CEE37 pKa = 4.0LKK39 pKa = 10.37KK40 pKa = 10.79SYY42 pKa = 10.28SGSPFAFIEE51 pKa = 4.63FSDD54 pKa = 4.05SRR56 pKa = 11.84DD57 pKa = 3.31ARR59 pKa = 11.84DD60 pKa = 4.03AIRR63 pKa = 11.84DD64 pKa = 3.25KK65 pKa = 11.21DD66 pKa = 3.57GYY68 pKa = 10.0EE69 pKa = 3.77FHH71 pKa = 6.77GKK73 pKa = 9.25KK74 pKa = 10.27LRR76 pKa = 11.84VEE78 pKa = 3.89LPFRR82 pKa = 11.84YY83 pKa = 8.99KK84 pKa = 10.73DD85 pKa = 3.44EE86 pKa = 4.09PRR88 pKa = 11.84RR89 pKa = 11.84PSGRR93 pKa = 11.84RR94 pKa = 11.84YY95 pKa = 8.06RR96 pKa = 11.84TTRR99 pKa = 11.84RR100 pKa = 11.84GKK102 pKa = 10.12YY103 pKa = 8.06VLEE106 pKa = 4.31VTGLPPSGSWQDD118 pKa = 4.13LKK120 pKa = 11.74DD121 pKa = 3.54HH122 pKa = 6.3MRR124 pKa = 11.84DD125 pKa = 3.3AGEE128 pKa = 4.73CGHH131 pKa = 7.15ADD133 pKa = 3.49VFRR136 pKa = 11.84GGVGEE141 pKa = 3.83ITFFSRR147 pKa = 11.84SDD149 pKa = 2.89MDD151 pKa = 3.71YY152 pKa = 10.86AIEE155 pKa = 4.4RR156 pKa = 11.84FDD158 pKa = 3.48GSTFRR163 pKa = 11.84SHH165 pKa = 6.75EE166 pKa = 4.25GEE168 pKa = 3.66KK169 pKa = 10.62SRR171 pKa = 11.84ISVRR175 pKa = 11.84EE176 pKa = 3.34KK177 pKa = 9.34SRR179 pKa = 11.84RR180 pKa = 11.84RR181 pKa = 11.84RR182 pKa = 11.84TRR184 pKa = 11.84SYY186 pKa = 10.44SRR188 pKa = 11.84DD189 pKa = 3.07RR190 pKa = 11.84GRR192 pKa = 11.84SYY194 pKa = 11.17SRR196 pKa = 11.84NNRR199 pKa = 11.84RR200 pKa = 11.84SRR202 pKa = 11.84SYY204 pKa = 9.99SRR206 pKa = 11.84SRR208 pKa = 11.84TRR210 pKa = 11.84SRR212 pKa = 11.84SRR214 pKa = 11.84TRR216 pKa = 11.84DD217 pKa = 2.92RR218 pKa = 11.84SRR220 pKa = 11.84DD221 pKa = 3.22RR222 pKa = 11.84SRR224 pKa = 11.84SRR226 pKa = 11.84DD227 pKa = 3.28RR228 pKa = 11.84NRR230 pKa = 11.84DD231 pKa = 3.3RR232 pKa = 11.84TSSRR236 pKa = 11.84SYY238 pKa = 11.31SRR240 pKa = 11.84DD241 pKa = 3.1KK242 pKa = 11.09SDD244 pKa = 3.29SRR246 pKa = 11.84SRR248 pKa = 11.84DD249 pKa = 3.2KK250 pKa = 10.79TVSRR254 pKa = 11.84SRR256 pKa = 11.84SS257 pKa = 3.31

Molecular weight: 30.57 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4071

0

4071

1895349

19

4593

465.6

53.32

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

3.421 ± 0.034

1.661 ± 0.017

5.872 ± 0.032

6.368 ± 0.041

4.953 ± 0.028

4.469 ± 0.03

2.16 ± 0.015

6.565 ± 0.043

7.829 ± 0.042

10.186 ± 0.05

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.033 ± 0.017

7.262 ± 0.05

3.946 ± 0.032

3.194 ± 0.033

4.139 ± 0.026

8.725 ± 0.042

5.901 ± 0.036

6.235 ± 0.029

0.795 ± 0.009

4.286 ± 0.028
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski