Candidatus Coxiella mudrowiae

Taxonomy: cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae; Coxiella

Average proteome isoelectric point is 7.33

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 822 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A0H4UXP7|A0A0H4UXP7_9COXI Coenzyme A biosynthesis bifunctional protein CoaBC OS=Candidatus Coxiella mudrowiae OX=2054173 GN=coaBC PE=3 SV=1
MM1 pKa = 7.08TFIVIDD7 pKa = 3.24NCIRR11 pKa = 11.84CKK13 pKa = 10.25YY14 pKa = 7.51TDD16 pKa = 3.93CVEE19 pKa = 4.15VCPVDD24 pKa = 4.28CFHH27 pKa = 7.48EE28 pKa = 5.32GPNMLVIDD36 pKa = 4.61PDD38 pKa = 3.57EE39 pKa = 5.96CIDD42 pKa = 4.49CNLCVPEE49 pKa = 4.98CPVDD53 pKa = 4.65AIFAEE58 pKa = 4.79DD59 pKa = 4.47DD60 pKa = 3.84LPEE63 pKa = 4.32EE64 pKa = 4.32KK65 pKa = 10.4QSFLKK70 pKa = 10.98LNAEE74 pKa = 4.77LAKK77 pKa = 9.85QWPIITAKK85 pKa = 10.58KK86 pKa = 8.98EE87 pKa = 4.06APEE90 pKa = 5.34DD91 pKa = 3.84ADD93 pKa = 4.52DD94 pKa = 4.67WADD97 pKa = 3.76TPDD100 pKa = 3.26KK101 pKa = 10.82LQYY104 pKa = 10.56LEE106 pKa = 5.36HH107 pKa = 6.7EE108 pKa = 4.34WSEE111 pKa = 4.12

Molecular weight:
12.72 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A0H4USB9|A0A0H4USB9_9COXI ATP synthase subunit beta OS=Candidatus Coxiella mudrowiae OX=2054173 GN=atpD PE=3 SV=1
MM1 pKa = 7.35KK2 pKa = 9.43RR3 pKa = 11.84TYY5 pKa = 10.28QPSKK9 pKa = 9.83LKK11 pKa = 10.65RR12 pKa = 11.84NRR14 pKa = 11.84THH16 pKa = 7.33GFRR19 pKa = 11.84TRR21 pKa = 11.84MAIKK25 pKa = 10.42NGRR28 pKa = 11.84QVLNRR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84AKK37 pKa = 9.8GRR39 pKa = 11.84KK40 pKa = 8.55HH41 pKa = 6.22LVVV44 pKa = 3.63

Molecular weight:
5.35 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

822

0

822

255510

40

1617

310.8

34.93

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.611 ± 0.072

1.077 ± 0.032

4.512 ± 0.057

6.381 ± 0.101

4.226 ± 0.071

6.601 ± 0.07

2.401 ± 0.035

7.856 ± 0.068

6.284 ± 0.073

10.818 ± 0.106

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.361 ± 0.036

4.204 ± 0.049

4.203 ± 0.042

4.217 ± 0.064

5.412 ± 0.067

5.849 ± 0.054

5.075 ± 0.055

6.586 ± 0.072

1.115 ± 0.034

3.21 ± 0.047

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski