Amino acid dipepetide frequency for Cryptotermes secundus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.569AlaAla: 5.569 ± 0.027
1.172AlaCys: 1.172 ± 0.014
3.213AlaAsp: 3.213 ± 0.018
4.447AlaGlu: 4.447 ± 0.027
2.191AlaPhe: 2.191 ± 0.014
3.772AlaGly: 3.772 ± 0.024
1.488AlaHis: 1.488 ± 0.013
2.891AlaIle: 2.891 ± 0.016
3.362AlaLys: 3.362 ± 0.019
5.855AlaLeu: 5.855 ± 0.028
1.505AlaMet: 1.505 ± 0.012
2.259AlaAsn: 2.259 ± 0.013
2.897AlaPro: 2.897 ± 0.022
2.48AlaGln: 2.48 ± 0.016
3.165AlaArg: 3.165 ± 0.017
5.12AlaSer: 5.12 ± 0.026
3.775AlaThr: 3.775 ± 0.02
4.925AlaVal: 4.925 ± 0.023
0.632AlaTrp: 0.632 ± 0.007
1.512AlaTyr: 1.512 ± 0.013
0.002AlaXaa: 0.002 ± 0.0
Cys
1.072CysAla: 1.072 ± 0.011
0.583CysCys: 0.583 ± 0.011
1.293CysAsp: 1.293 ± 0.016
1.268CysGlu: 1.268 ± 0.014
0.819CysPhe: 0.819 ± 0.009
1.448CysGly: 1.448 ± 0.017
0.643CysHis: 0.643 ± 0.008
1.063CysIle: 1.063 ± 0.011
1.159CysLys: 1.159 ± 0.011
1.933CysLeu: 1.933 ± 0.017
0.452CysMet: 0.452 ± 0.006
1.051CysAsn: 1.051 ± 0.015
1.012CysPro: 1.012 ± 0.014
0.844CysGln: 0.844 ± 0.012
1.151CysArg: 1.151 ± 0.013
1.839CysSer: 1.839 ± 0.017
1.089CysThr: 1.089 ± 0.011
1.352CysVal: 1.352 ± 0.015
0.248CysTrp: 0.248 ± 0.005
0.613CysTyr: 0.613 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
2.967AspAla: 2.967 ± 0.017
1.072AspCys: 1.072 ± 0.016
3.491AspAsp: 3.491 ± 0.025
4.008AspGlu: 4.008 ± 0.023
2.127AspPhe: 2.127 ± 0.013
3.287AspGly: 3.287 ± 0.022
1.236AspHis: 1.236 ± 0.01
3.303AspIle: 3.303 ± 0.018
2.935AspLys: 2.935 ± 0.02
4.866AspLeu: 4.866 ± 0.025
1.369AspMet: 1.369 ± 0.011
2.113AspAsn: 2.113 ± 0.013
2.383AspPro: 2.383 ± 0.018
1.854AspGln: 1.854 ± 0.012
2.82AspArg: 2.82 ± 0.019
4.468AspSer: 4.468 ± 0.022
2.944AspThr: 2.944 ± 0.017
3.837AspVal: 3.837 ± 0.019
0.676AspTrp: 0.676 ± 0.009
1.552AspTyr: 1.552 ± 0.011
0.001AspXaa: 0.001 ± 0.0
Glu
4.369GluAla: 4.369 ± 0.028
1.262GluCys: 1.262 ± 0.015
4.444GluAsp: 4.444 ± 0.023
7.184GluGlu: 7.184 ± 0.062
2.147GluPhe: 2.147 ± 0.014
3.75GluGly: 3.75 ± 0.02
1.682GluHis: 1.682 ± 0.014
3.541GluIle: 3.541 ± 0.025
4.987GluLys: 4.987 ± 0.041
6.19GluLeu: 6.19 ± 0.036
1.837GluMet: 1.837 ± 0.013
3.313GluAsn: 3.313 ± 0.019
2.569GluPro: 2.569 ± 0.021
3.001GluGln: 3.001 ± 0.024
4.027GluArg: 4.027 ± 0.028
4.635GluSer: 4.635 ± 0.028
3.893GluThr: 3.893 ± 0.025
4.58GluVal: 4.58 ± 0.027
0.699GluTrp: 0.699 ± 0.008
1.754GluTyr: 1.754 ± 0.012
0.001GluXaa: 0.001 ± 0.0
Phe
1.905PheAla: 1.905 ± 0.013
0.899PheCys: 0.899 ± 0.011
1.731PheAsp: 1.731 ± 0.011
2.076PheGlu: 2.076 ± 0.014
1.41PhePhe: 1.41 ± 0.014
2.212PheGly: 2.212 ± 0.018
1.097PheHis: 1.097 ± 0.01
1.832PheIle: 1.832 ± 0.015
1.883PheLys: 1.883 ± 0.013
3.625PheLeu: 3.625 ± 0.021
0.808PheMet: 0.808 ± 0.009
1.466PheAsn: 1.466 ± 0.012
1.792PhePro: 1.792 ± 0.012
1.601PheGln: 1.601 ± 0.012
2.063PheArg: 2.063 ± 0.016
3.142PheSer: 3.142 ± 0.02
2.059PheThr: 2.059 ± 0.015
2.31PheVal: 2.31 ± 0.016
0.443PheTrp: 0.443 ± 0.006
1.1PheTyr: 1.1 ± 0.011
0.001PheXaa: 0.001 ± 0.0
Gly
3.369GlyAla: 3.369 ± 0.019
1.112GlyCys: 1.112 ± 0.013
3.317GlyAsp: 3.317 ± 0.019
3.751GlyGlu: 3.751 ± 0.025
2.137GlyPhe: 2.137 ± 0.016
4.678GlyGly: 4.678 ± 0.047
1.643GlyHis: 1.643 ± 0.016
3.08GlyIle: 3.08 ± 0.02
3.619GlyLys: 3.619 ± 0.02
4.7GlyLeu: 4.7 ± 0.028
1.428GlyMet: 1.428 ± 0.012
2.769GlyAsn: 2.769 ± 0.021
2.636GlyPro: 2.636 ± 0.031
2.287GlyGln: 2.287 ± 0.019
3.442GlyArg: 3.442 ± 0.022
5.484GlySer: 5.484 ± 0.033
3.475GlyThr: 3.475 ± 0.019
3.611GlyVal: 3.611 ± 0.019
0.651GlyTrp: 0.651 ± 0.008
1.81GlyTyr: 1.81 ± 0.013
0.001GlyXaa: 0.001 ± 0.0
His
1.42HisAla: 1.42 ± 0.012
0.681HisCys: 0.681 ± 0.008
1.227HisAsp: 1.227 ± 0.009
1.548HisGlu: 1.548 ± 0.012
1.094HisPhe: 1.094 ± 0.011
1.543HisGly: 1.543 ± 0.013
1.184HisHis: 1.184 ± 0.015
1.549HisIle: 1.549 ± 0.012
1.539HisLys: 1.539 ± 0.013
2.846HisLeu: 2.846 ± 0.02
0.722HisMet: 0.722 ± 0.008
1.214HisAsn: 1.214 ± 0.011
1.453HisPro: 1.453 ± 0.012
1.479HisGln: 1.479 ± 0.016
1.669HisArg: 1.669 ± 0.012
2.472HisSer: 2.472 ± 0.018
1.635HisThr: 1.635 ± 0.014
1.766HisVal: 1.766 ± 0.013
0.318HisTrp: 0.318 ± 0.005
0.852HisTyr: 0.852 ± 0.008
0.0HisXaa: 0.0 ± 0.0
Ile
3.079IleAla: 3.079 ± 0.015
1.143IleCys: 1.143 ± 0.01
2.469IleAsp: 2.469 ± 0.015
3.05IleGlu: 3.05 ± 0.02
1.886IlePhe: 1.886 ± 0.013
2.578IleGly: 2.578 ± 0.019
1.546IleHis: 1.546 ± 0.018
2.77IleIle: 2.77 ± 0.018
2.993IleLys: 2.993 ± 0.021
4.867IleLeu: 4.867 ± 0.023
1.15IleMet: 1.15 ± 0.011
2.118IleAsn: 2.118 ± 0.016
2.703IlePro: 2.703 ± 0.016
2.281IleGln: 2.281 ± 0.015
2.65IleArg: 2.65 ± 0.014
4.234IleSer: 4.234 ± 0.025
2.931IleThr: 2.931 ± 0.018
3.144IleVal: 3.144 ± 0.018
0.538IleTrp: 0.538 ± 0.007
1.375IleTyr: 1.375 ± 0.013
0.001IleXaa: 0.001 ± 0.0
Lys
3.58LysAla: 3.58 ± 0.022
1.266LysCys: 1.266 ± 0.012
3.204LysAsp: 3.204 ± 0.019
5.03LysGlu: 5.03 ± 0.044
2.031LysPhe: 2.031 ± 0.014
2.963LysGly: 2.963 ± 0.02
1.672LysHis: 1.672 ± 0.015
3.224LysIle: 3.224 ± 0.02
5.191LysLys: 5.191 ± 0.043
5.803LysLeu: 5.803 ± 0.028
1.541LysMet: 1.541 ± 0.01
2.621LysAsn: 2.621 ± 0.017
2.942LysPro: 2.942 ± 0.038
2.737LysGln: 2.737 ± 0.018
3.629LysArg: 3.629 ± 0.022
4.397LysSer: 4.397 ± 0.029
3.361LysThr: 3.361 ± 0.019
3.826LysVal: 3.826 ± 0.02
0.7LysTrp: 0.7 ± 0.007
1.825LysTyr: 1.825 ± 0.014
0.002LysXaa: 0.002 ± 0.0
Leu
5.826LeuAla: 5.826 ± 0.028
1.986LeuCys: 1.986 ± 0.015
4.744LeuAsp: 4.744 ± 0.022
6.463LeuGlu: 6.463 ± 0.038
3.123LeuPhe: 3.123 ± 0.02
4.893LeuGly: 4.893 ± 0.022
2.916LeuHis: 2.916 ± 0.021
3.952LeuIle: 3.952 ± 0.022
6.138LeuLys: 6.138 ± 0.03
9.24LeuLeu: 9.24 ± 0.048
2.065LeuMet: 2.065 ± 0.013
3.912LeuAsn: 3.912 ± 0.021
4.828LeuPro: 4.828 ± 0.024
5.222LeuGln: 5.222 ± 0.034
5.349LeuArg: 5.349 ± 0.027
7.34LeuSer: 7.34 ± 0.03
5.028LeuThr: 5.028 ± 0.022
5.472LeuVal: 5.472 ± 0.027
0.975LeuTrp: 0.975 ± 0.01
2.643LeuTyr: 2.643 ± 0.019
0.001LeuXaa: 0.001 ± 0.0
Met
1.765MetAla: 1.765 ± 0.012
0.482MetCys: 0.482 ± 0.006
1.329MetAsp: 1.329 ± 0.011
1.813MetGlu: 1.813 ± 0.014
0.868MetPhe: 0.868 ± 0.009
1.288MetGly: 1.288 ± 0.014
0.506MetHis: 0.506 ± 0.006
0.957MetIle: 0.957 ± 0.01
1.704MetLys: 1.704 ± 0.013
2.206MetLeu: 2.206 ± 0.014
0.644MetMet: 0.644 ± 0.007
1.05MetAsn: 1.05 ± 0.01
1.047MetPro: 1.047 ± 0.01
1.056MetGln: 1.056 ± 0.009
1.188MetArg: 1.188 ± 0.011
1.874MetSer: 1.874 ± 0.015
1.251MetThr: 1.251 ± 0.011
1.418MetVal: 1.418 ± 0.01
0.301MetTrp: 0.301 ± 0.004
0.685MetTyr: 0.685 ± 0.008
0.0MetXaa: 0.0 ± 0.0
Asn
2.39AsnAla: 2.39 ± 0.015
0.939AsnCys: 0.939 ± 0.011
1.929AsnAsp: 1.929 ± 0.012
2.69AsnGlu: 2.69 ± 0.017
1.633AsnPhe: 1.633 ± 0.013
2.54AsnGly: 2.54 ± 0.02
1.153AsnHis: 1.153 ± 0.011
2.842AsnIle: 2.842 ± 0.018
2.823AsnLys: 2.823 ± 0.018
3.994AsnLeu: 3.994 ± 0.02
1.143AsnMet: 1.143 ± 0.011
2.325AsnAsn: 2.325 ± 0.022
2.046AsnPro: 2.046 ± 0.017
1.66AsnGln: 1.66 ± 0.015
2.262AsnArg: 2.262 ± 0.011
3.799AsnSer: 3.799 ± 0.023
2.466AsnThr: 2.466 ± 0.017
2.977AsnVal: 2.977 ± 0.018
0.503AsnTrp: 0.503 ± 0.007
1.366AsnTyr: 1.366 ± 0.013
0.001AsnXaa: 0.001 ± 0.0
Pro
3.315ProAla: 3.315 ± 0.018
0.852ProCys: 0.852 ± 0.014
2.669ProAsp: 2.669 ± 0.016
3.419ProGlu: 3.419 ± 0.03
1.717ProPhe: 1.717 ± 0.016
3.251ProGly: 3.251 ± 0.04
1.511ProHis: 1.511 ± 0.012
2.043ProIle: 2.043 ± 0.013
2.516ProLys: 2.516 ± 0.021
4.23ProLeu: 4.23 ± 0.021
0.924ProMet: 0.924 ± 0.01
1.919ProAsn: 1.919 ± 0.015
4.438ProPro: 4.438 ± 0.057
2.386ProGln: 2.386 ± 0.022
2.472ProArg: 2.472 ± 0.019
4.753ProSer: 4.753 ± 0.032
3.049ProThr: 3.049 ± 0.026
3.841ProVal: 3.841 ± 0.026
0.498ProTrp: 0.498 ± 0.006
1.48ProTyr: 1.48 ± 0.013
0.001ProXaa: 0.001 ± 0.0
Gln
2.698GlnAla: 2.698 ± 0.018
0.912GlnCys: 0.912 ± 0.012
2.152GlnAsp: 2.152 ± 0.014
3.39GlnGlu: 3.39 ± 0.021
1.48GlnPhe: 1.48 ± 0.011
2.339GlnGly: 2.339 ± 0.02
1.516GlnHis: 1.516 ± 0.015
2.014GlnIle: 2.014 ± 0.014
2.794GlnLys: 2.794 ± 0.021
4.432GlnLeu: 4.432 ± 0.028
1.099GlnMet: 1.099 ± 0.01
2.093GlnAsn: 2.093 ± 0.017
2.254GlnPro: 2.254 ± 0.022
3.772GlnGln: 3.772 ± 0.056
2.743GlnArg: 2.743 ± 0.019
3.112GlnSer: 3.112 ± 0.021
2.315GlnThr: 2.315 ± 0.016
2.716GlnVal: 2.716 ± 0.018
0.524GlnTrp: 0.524 ± 0.007
1.26GlnTyr: 1.26 ± 0.012
0.001GlnXaa: 0.001 ± 0.0
Arg
3.094ArgAla: 3.094 ± 0.02
1.101ArgCys: 1.101 ± 0.014
2.976ArgAsp: 2.976 ± 0.021
3.785ArgGlu: 3.785 ± 0.023
1.902ArgPhe: 1.902 ± 0.011
3.145ArgGly: 3.145 ± 0.023
1.711ArgHis: 1.711 ± 0.013
2.864ArgIle: 2.864 ± 0.018
4.086ArgLys: 4.086 ± 0.021
5.06ArgLeu: 5.06 ± 0.023
1.297ArgMet: 1.297 ± 0.011
2.7ArgAsn: 2.7 ± 0.017
2.698ArgPro: 2.698 ± 0.02
2.572ArgGln: 2.572 ± 0.015
4.416ArgArg: 4.416 ± 0.028
4.302ArgSer: 4.302 ± 0.03
2.931ArgThr: 2.931 ± 0.014
3.175ArgVal: 3.175 ± 0.017
0.701ArgTrp: 0.701 ± 0.008
1.593ArgTyr: 1.593 ± 0.013
0.001ArgXaa: 0.001 ± 0.0
Ser
5.213SerAla: 5.213 ± 0.023
1.704SerCys: 1.704 ± 0.016
4.626SerAsp: 4.626 ± 0.024
5.297SerGlu: 5.297 ± 0.029
2.815SerPhe: 2.815 ± 0.02
5.646SerGly: 5.646 ± 0.041
2.334SerHis: 2.334 ± 0.016
3.549SerIle: 3.549 ± 0.018
4.43SerLys: 4.43 ± 0.024
7.355SerLeu: 7.355 ± 0.029
1.625SerMet: 1.625 ± 0.012
3.549SerAsn: 3.549 ± 0.023
4.856SerPro: 4.856 ± 0.032
3.557SerGln: 3.557 ± 0.021
4.453SerArg: 4.453 ± 0.025
9.615SerSer: 9.615 ± 0.063
4.931SerThr: 4.931 ± 0.027
5.793SerVal: 5.793 ± 0.025
0.878SerTrp: 0.878 ± 0.008
2.136SerTyr: 2.136 ± 0.016
0.001SerXaa: 0.001 ± 0.0
Thr
4.079ThrAla: 4.079 ± 0.021
1.153ThrCys: 1.153 ± 0.013
2.996ThrAsp: 2.996 ± 0.015
3.941ThrGlu: 3.941 ± 0.033
1.97ThrPhe: 1.97 ± 0.013
3.662ThrGly: 3.662 ± 0.02
1.467ThrHis: 1.467 ± 0.014
2.561ThrIle: 2.561 ± 0.015
3.092ThrLys: 3.092 ± 0.019
5.142ThrLeu: 5.142 ± 0.023
1.181ThrMet: 1.181 ± 0.01
2.315ThrAsn: 2.315 ± 0.015
3.356ThrPro: 3.356 ± 0.023
2.277ThrGln: 2.277 ± 0.017
2.665ThrArg: 2.665 ± 0.014
5.33ThrSer: 5.33 ± 0.029
3.704ThrThr: 3.704 ± 0.034
4.463ThrVal: 4.463 ± 0.021
0.7ThrTrp: 0.7 ± 0.008
1.529ThrTyr: 1.529 ± 0.015
0.001ThrXaa: 0.001 ± 0.0
Val
4.45ValAla: 4.45 ± 0.021
1.643ValCys: 1.643 ± 0.017
3.428ValAsp: 3.428 ± 0.017
4.346ValGlu: 4.346 ± 0.024
2.384ValPhe: 2.384 ± 0.016
3.569ValGly: 3.569 ± 0.02
1.752ValHis: 1.752 ± 0.012
3.266ValIle: 3.266 ± 0.018
3.861ValLys: 3.861 ± 0.021
6.041ValLeu: 6.041 ± 0.028
1.635ValMet: 1.635 ± 0.013
2.805ValAsn: 2.805 ± 0.016
3.684ValPro: 3.684 ± 0.025
2.859ValGln: 2.859 ± 0.018
3.502ValArg: 3.502 ± 0.019
5.352ValSer: 5.352 ± 0.026
4.524ValThr: 4.524 ± 0.026
4.433ValVal: 4.433 ± 0.027
0.736ValTrp: 0.736 ± 0.009
1.816ValTyr: 1.816 ± 0.013
0.002ValXaa: 0.002 ± 0.0
Trp
0.571TrpAla: 0.571 ± 0.007
0.259TrpCys: 0.259 ± 0.004
0.63TrpAsp: 0.63 ± 0.008
0.71TrpGlu: 0.71 ± 0.007
0.468TrpPhe: 0.468 ± 0.006
0.618TrpGly: 0.618 ± 0.008
0.286TrpHis: 0.286 ± 0.005
0.593TrpIle: 0.593 ± 0.006
0.828TrpLys: 0.828 ± 0.009
1.095TrpLeu: 1.095 ± 0.011
0.276TrpMet: 0.276 ± 0.005
0.586TrpAsn: 0.586 ± 0.007
0.44TrpPro: 0.44 ± 0.006
0.494TrpGln: 0.494 ± 0.006
0.731TrpArg: 0.731 ± 0.008
0.807TrpSer: 0.807 ± 0.01
0.666TrpThr: 0.666 ± 0.009
0.659TrpVal: 0.659 ± 0.007
0.168TrpTrp: 0.168 ± 0.004
0.34TrpTyr: 0.34 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.501TyrAla: 1.501 ± 0.013
0.712TyrCys: 0.712 ± 0.008
1.443TyrAsp: 1.443 ± 0.012
1.648TyrGlu: 1.648 ± 0.012
1.255TyrPhe: 1.255 ± 0.011
1.816TyrGly: 1.816 ± 0.015
0.869TyrHis: 0.869 ± 0.008
1.611TyrIle: 1.611 ± 0.012
1.604TyrLys: 1.604 ± 0.014
2.631TyrLeu: 2.631 ± 0.018
0.727TyrMet: 0.727 ± 0.007
1.3TyrAsn: 1.3 ± 0.012
1.245TyrPro: 1.245 ± 0.012
1.2TyrGln: 1.2 ± 0.01
1.711TyrArg: 1.711 ± 0.012
2.288TyrSer: 2.288 ± 0.015
1.557TyrThr: 1.557 ± 0.012
1.788TyrVal: 1.788 ± 0.014
0.336TyrTrp: 0.336 ± 0.006
0.995TyrTyr: 0.995 ± 0.01
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.0
0.001XaaCys: 0.001 ± 0.0
0.001XaaAsp: 0.001 ± 0.0
0.001XaaGlu: 0.001 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.001XaaIle: 0.001 ± 0.0
0.001XaaLys: 0.001 ± 0.0
0.002XaaLeu: 0.002 ± 0.0
0.002XaaMet: 0.002 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.001XaaPro: 0.001 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.001XaaArg: 0.001 ± 0.0
0.002XaaSer: 0.002 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
0.383XaaXaa: 0.383 ± 0.057
Statistics based on 27252 proteins (13199505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski