Betapapillomavirus 4

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Betapapillomavirus

Average proteome isoelectric point is 5.82

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A2D2AL17|A0A2D2AL17_9PAPI Regulatory protein E2 OS=Betapapillomavirus 4 OX=334208 GN=E2 PE=3 SV=1
MM1 pKa = 7.6IGKK4 pKa = 8.64QATIPEE10 pKa = 4.39IVLDD14 pKa = 4.27LQDD17 pKa = 4.12LVQPIDD23 pKa = 3.44LHH25 pKa = 8.22CDD27 pKa = 3.25EE28 pKa = 5.03EE29 pKa = 4.89LEE31 pKa = 4.28NQVEE35 pKa = 4.37EE36 pKa = 4.62EE37 pKa = 4.23PAPQRR42 pKa = 11.84IDD44 pKa = 3.45YY45 pKa = 10.25KK46 pKa = 10.65IVSSCGGCGIKK57 pKa = 10.43LRR59 pKa = 11.84IFATCTQFGIRR70 pKa = 11.84TLQDD74 pKa = 3.47LLLEE78 pKa = 4.9EE79 pKa = 4.78IALLCPDD86 pKa = 4.81CKK88 pKa = 10.68NGRR91 pKa = 3.72

Molecular weight:
10.17 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A2D2AL52|A0A2D2AL52_9PAPI Protein E6 OS=Betapapillomavirus 4 OX=334208 GN=E6 PE=3 SV=1
MM1 pKa = 7.5EE2 pKa = 5.42ALSDD6 pKa = 4.12RR7 pKa = 11.84FNALQDD13 pKa = 3.51KK14 pKa = 10.97LMTIYY19 pKa = 10.57EE20 pKa = 4.33KK21 pKa = 10.81ASEE24 pKa = 4.26SLTDD28 pKa = 5.54QIEE31 pKa = 4.11HH32 pKa = 6.5WNLLRR37 pKa = 11.84QEE39 pKa = 4.21QVLFHH44 pKa = 6.04YY45 pKa = 10.25ARR47 pKa = 11.84QRR49 pKa = 11.84GVMRR53 pKa = 11.84LGYY56 pKa = 10.1QPVPALTISEE66 pKa = 4.36AKK68 pKa = 10.21AKK70 pKa = 10.0EE71 pKa = 4.12AIAMVLHH78 pKa = 6.59LEE80 pKa = 4.11ALQRR84 pKa = 11.84SPYY87 pKa = 10.01KK88 pKa = 10.23DD89 pKa = 3.66EE90 pKa = 4.24KK91 pKa = 8.2WTLVNTSVEE100 pKa = 4.39TFRR103 pKa = 11.84TPPEE107 pKa = 3.76NCFKK111 pKa = 10.82KK112 pKa = 10.56GPKK115 pKa = 9.09TIEE118 pKa = 3.58IVYY121 pKa = 10.4DD122 pKa = 3.78GNPDD126 pKa = 2.96NTMLYY131 pKa = 9.05TIWTFIYY138 pKa = 11.02YY139 pKa = 10.31EE140 pKa = 4.44DD141 pKa = 6.11DD142 pKa = 3.26EE143 pKa = 5.95GNWQKK148 pKa = 9.59TEE150 pKa = 3.87GQLDD154 pKa = 3.69YY155 pKa = 11.36HH156 pKa = 6.29GAYY159 pKa = 10.5YY160 pKa = 10.95LDD162 pKa = 4.19GLNKK166 pKa = 9.71QYY168 pKa = 10.88YY169 pKa = 9.58IRR171 pKa = 11.84FAQDD175 pKa = 2.32ARR177 pKa = 11.84RR178 pKa = 11.84YY179 pKa = 9.75SEE181 pKa = 3.82TGEE184 pKa = 4.01WEE186 pKa = 4.2VKK188 pKa = 10.11FNNEE192 pKa = 3.3ILFAPVTSSTNSEE205 pKa = 4.13EE206 pKa = 4.22EE207 pKa = 3.85RR208 pKa = 11.84DD209 pKa = 3.94RR210 pKa = 11.84PAPASDD216 pKa = 4.23PGSLPQTSGRR226 pKa = 11.84LSPSPVQRR234 pKa = 11.84KK235 pKa = 7.21QLSKK239 pKa = 10.48RR240 pKa = 11.84RR241 pKa = 11.84YY242 pKa = 7.71GRR244 pKa = 11.84KK245 pKa = 9.65DD246 pKa = 3.22SSPTATSRR254 pKa = 11.84VQRR257 pKa = 11.84RR258 pKa = 11.84PKK260 pKa = 10.18ASPRR264 pKa = 11.84RR265 pKa = 11.84SRR267 pKa = 11.84SRR269 pKa = 11.84SGSRR273 pKa = 11.84SGSQGDD279 pKa = 3.62ARR281 pKa = 11.84TLLSLRR287 pKa = 11.84RR288 pKa = 11.84GEE290 pKa = 4.1RR291 pKa = 11.84EE292 pKa = 3.63RR293 pKa = 11.84GEE295 pKa = 4.04GRR297 pKa = 11.84GTGIRR302 pKa = 11.84VRR304 pKa = 11.84GRR306 pKa = 11.84SGSRR310 pKa = 11.84GRR312 pKa = 11.84SRR314 pKa = 11.84SRR316 pKa = 11.84SRR318 pKa = 11.84SRR320 pKa = 11.84SRR322 pKa = 11.84SRR324 pKa = 11.84SRR326 pKa = 11.84SRR328 pKa = 11.84SSRR331 pKa = 11.84SRR333 pKa = 11.84GRR335 pKa = 11.84GNTTTRR341 pKa = 11.84GRR343 pKa = 11.84GGYY346 pKa = 7.01RR347 pKa = 11.84TRR349 pKa = 11.84RR350 pKa = 11.84SRR352 pKa = 11.84SKK354 pKa = 11.01SVDD357 pKa = 3.07TSGIPPDD364 pKa = 3.38QVGRR368 pKa = 11.84SLQSVGRR375 pKa = 11.84QHH377 pKa = 6.97SGRR380 pKa = 11.84LARR383 pKa = 11.84LLDD386 pKa = 3.84EE387 pKa = 5.59ARR389 pKa = 11.84DD390 pKa = 3.77PPVILLKK397 pKa = 11.05GKK399 pKa = 10.59ANTLKK404 pKa = 10.49CYY406 pKa = 10.29RR407 pKa = 11.84YY408 pKa = 9.45RR409 pKa = 11.84AKK411 pKa = 10.46EE412 pKa = 3.99KK413 pKa = 10.72YY414 pKa = 8.94KK415 pKa = 10.68GYY417 pKa = 9.79YY418 pKa = 10.1DD419 pKa = 3.54RR420 pKa = 11.84VSTTWSWVGAGSNDD434 pKa = 3.64RR435 pKa = 11.84IGRR438 pKa = 11.84SRR440 pKa = 11.84MLFSFTSKK448 pKa = 9.95SQRR451 pKa = 11.84QMFLNIMKK459 pKa = 10.12LPKK462 pKa = 10.5GVDD465 pKa = 2.93WSFGCFDD472 pKa = 4.93SII474 pKa = 5.05

Molecular weight:
54.33 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2554

91

612

364.9

41.1

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.951 ± 0.4

2.271 ± 0.86

6.46 ± 0.427

6.852 ± 0.545

3.876 ± 0.425

6.891 ± 0.792

1.879 ± 0.257

4.777 ± 0.654

5.442 ± 0.789

8.614 ± 0.78

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.331 ± 0.281

4.15 ± 0.551

5.873 ± 0.778

4.62 ± 0.282

7.009 ± 1.4

7.244 ± 1.023

6.147 ± 0.908

5.912 ± 0.679

1.253 ± 0.292

3.446 ± 0.246

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski