Human papillomavirus 204

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Mupapillomavirus; Mupapillomavirus 3

Average proteome isoelectric point is 6.15

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0F7GGY8|A0A0F7GGY8_9PAPI Protein E6 OS=Human papillomavirus 204 OX=1650736 GN=E6 PE=3 SV=1
MM1 pKa = 7.26RR2 pKa = 11.84QEE4 pKa = 3.66NLAARR9 pKa = 11.84LEE11 pKa = 4.51TILLEE16 pKa = 4.17EE17 pKa = 4.6EE18 pKa = 4.42PNVLDD23 pKa = 3.26LHH25 pKa = 7.05CYY27 pKa = 10.37EE28 pKa = 4.83EE29 pKa = 4.46VALSDD34 pKa = 4.02EE35 pKa = 4.63EE36 pKa = 5.09EE37 pKa = 4.38EE38 pKa = 4.41SQQVQQPYY46 pKa = 10.58LVTVPCAQCLNVVTFTCAADD66 pKa = 3.69LLSIRR71 pKa = 11.84EE72 pKa = 4.08LQQLLFDD79 pKa = 4.78CLFLCEE85 pKa = 3.96TCAAEE90 pKa = 4.93LSS92 pKa = 3.94

Molecular weight: 10.44 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0F7GG55|A0A0F7GG55_9PAPI Protein E7 OS=Human papillomavirus 204 OX=1650736 GN=E7 PE=3 SV=1
MM1 pKa = 7.66EE2 pKa = 5.39NLSQRR7 pKa = 11.84LEE9 pKa = 4.17SLQEE13 pKa = 3.95RR14 pKa = 11.84LLSLYY19 pKa = 10.04EE20 pKa = 3.82QDD22 pKa = 4.89SNDD25 pKa = 3.17IQDD28 pKa = 5.09QITHH32 pKa = 5.25WTLIKK37 pKa = 10.21QEE39 pKa = 4.09QVLFHH44 pKa = 6.01YY45 pKa = 10.33ARR47 pKa = 11.84QNGVRR52 pKa = 11.84RR53 pKa = 11.84LGMQTIPTLAASEE66 pKa = 4.24ARR68 pKa = 11.84AKK70 pKa = 10.04QAIEE74 pKa = 4.12MVLQLQSLANSPFGMEE90 pKa = 3.79PWLLQDD96 pKa = 3.74TSRR99 pKa = 11.84EE100 pKa = 4.08RR101 pKa = 11.84YY102 pKa = 6.59TAAPGNTFKK111 pKa = 10.94KK112 pKa = 10.29QPQTLLLTFDD122 pKa = 3.7NDD124 pKa = 3.14KK125 pKa = 11.3DD126 pKa = 3.76NSVEE130 pKa = 4.19HH131 pKa = 5.74TVWTYY136 pKa = 10.82IYY138 pKa = 8.74YY139 pKa = 10.59QNGDD143 pKa = 4.2GIWHH147 pKa = 6.49KK148 pKa = 10.74EE149 pKa = 3.7EE150 pKa = 4.53SGVDD154 pKa = 3.16EE155 pKa = 5.08KK156 pKa = 11.73GIFFIKK162 pKa = 10.65YY163 pKa = 8.04GVEE166 pKa = 3.71KK167 pKa = 9.9IYY169 pKa = 10.86YY170 pKa = 10.26LSFADD175 pKa = 3.39EE176 pKa = 4.0ATRR179 pKa = 11.84YY180 pKa = 8.79SRR182 pKa = 11.84KK183 pKa = 10.22GEE185 pKa = 3.96YY186 pKa = 8.74TVHH189 pKa = 6.87FKK191 pKa = 10.0SQRR194 pKa = 11.84HH195 pKa = 5.15SYY197 pKa = 9.41NVSSVSSTSGSPGSPDD213 pKa = 3.05STEE216 pKa = 4.18TNPSSSHH223 pKa = 4.05TRR225 pKa = 11.84GAEE228 pKa = 3.86EE229 pKa = 4.28EE230 pKa = 4.43SPEE233 pKa = 4.01RR234 pKa = 11.84PVRR237 pKa = 11.84SRR239 pKa = 11.84AYY241 pKa = 8.99GQRR244 pKa = 11.84PSTSPRR250 pKa = 11.84VSSRR254 pKa = 11.84RR255 pKa = 11.84GGEE258 pKa = 3.7QGKK261 pKa = 10.16SGTGTDD267 pKa = 3.87SDD269 pKa = 4.32SGLAPPSPGDD279 pKa = 3.35VGSRR283 pKa = 11.84TTQPARR289 pKa = 11.84RR290 pKa = 11.84NQSRR294 pKa = 11.84LRR296 pKa = 11.84VLLQEE301 pKa = 4.48ARR303 pKa = 11.84DD304 pKa = 3.86PLVLCLKK311 pKa = 10.45GGPNQLKK318 pKa = 9.96CLRR321 pKa = 11.84YY322 pKa = 8.85RR323 pKa = 11.84LKK325 pKa = 10.55KK326 pKa = 9.25QHH328 pKa = 6.59HH329 pKa = 6.29KK330 pKa = 10.8LFTKK334 pKa = 10.47ISTTWHH340 pKa = 5.59WVDD343 pKa = 3.09NTSTNRR349 pKa = 11.84VGNARR354 pKa = 11.84MLIQFLTEE362 pKa = 3.57EE363 pKa = 4.24QRR365 pKa = 11.84NHH367 pKa = 6.35FLDD370 pKa = 4.37VIIVPKK376 pKa = 10.31DD377 pKa = 2.89ISVYY381 pKa = 9.83RR382 pKa = 11.84GYY384 pKa = 11.15FKK386 pKa = 11.26GFF388 pKa = 3.26

Molecular weight: 44.21 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2373

92

615

339.0

38.29

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.436 ± 0.368

1.686 ± 0.46

6.068 ± 0.426

6.321 ± 0.61

4.846 ± 0.413

5.647 ± 0.585

1.938 ± 0.222

5.394 ± 0.7

4.846 ± 0.799

9.524 ± 1.088

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.475 ± 0.223

4.888 ± 0.479

5.9 ± 0.867

5.015 ± 0.64

6.068 ± 0.707

8.007 ± 1.002

6.743 ± 0.283

5.942 ± 0.52

1.18 ± 0.306

3.076 ± 0.324
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski