Human parainfluenza virus 4a

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae; Rubulavirinae; Orthorubulavirus; Human orthorubulavirus 4

Average proteome isoelectric point is 6.72

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D7US56|D7US56_9MONO Phosphoprotein OS=Human parainfluenza virus 4a OX=11224 GN=P PE=3 SV=1
MM1 pKa = 7.36SSVLAAYY8 pKa = 7.88EE9 pKa = 4.01QFLQTTEE16 pKa = 3.81DD17 pKa = 3.48RR18 pKa = 11.84GFGDD22 pKa = 3.34QQFVQSDD29 pKa = 3.81TLKK32 pKa = 11.08AEE34 pKa = 3.85IPVFVLNTNDD44 pKa = 3.3PQQRR48 pKa = 11.84FTLMNFCLRR57 pKa = 11.84QAVSSSAKK65 pKa = 10.17SAIKK69 pKa = 10.28QGALLSLLSLQATSMQNHH87 pKa = 6.38LMIAARR93 pKa = 11.84APDD96 pKa = 3.33AALRR100 pKa = 11.84IIEE103 pKa = 4.45VDD105 pKa = 4.13AIDD108 pKa = 4.46PPDD111 pKa = 3.52YY112 pKa = 10.52TLTINPRR119 pKa = 11.84SGWDD123 pKa = 3.61DD124 pKa = 3.06IKK126 pKa = 10.97IRR128 pKa = 11.84AYY130 pKa = 10.26RR131 pKa = 11.84ALSRR135 pKa = 11.84DD136 pKa = 3.71LPISLADD143 pKa = 3.36RR144 pKa = 11.84TVFVSRR150 pKa = 11.84DD151 pKa = 3.38AEE153 pKa = 4.2HH154 pKa = 6.92AVCDD158 pKa = 5.68DD159 pKa = 2.9MDD161 pKa = 3.94TYY163 pKa = 11.5LNRR166 pKa = 11.84IFSVLIQVWIMVCKK180 pKa = 10.62CMTAYY185 pKa = 9.73DD186 pKa = 3.88QPTGSEE192 pKa = 3.93EE193 pKa = 3.9RR194 pKa = 11.84RR195 pKa = 11.84LAKK198 pKa = 10.33YY199 pKa = 9.15KK200 pKa = 9.87QQGRR204 pKa = 11.84MLEE207 pKa = 4.2RR208 pKa = 11.84YY209 pKa = 8.82QLQTDD214 pKa = 3.19ARR216 pKa = 11.84KK217 pKa = 9.88IIQLVIRR224 pKa = 11.84EE225 pKa = 4.33SMVIRR230 pKa = 11.84QFLVQEE236 pKa = 4.35MLTADD241 pKa = 3.31KK242 pKa = 11.11VGAYY246 pKa = 7.06TNRR249 pKa = 11.84YY250 pKa = 7.46YY251 pKa = 11.89AMVGDD256 pKa = 3.78IAKK259 pKa = 10.48YY260 pKa = 8.16IANVGMSAFFLTLKK274 pKa = 10.66FGLGNRR280 pKa = 11.84WKK282 pKa = 9.86PLALAAFSGEE292 pKa = 4.13LVKK295 pKa = 10.99LKK297 pKa = 10.94SLMSLYY303 pKa = 10.24RR304 pKa = 11.84RR305 pKa = 11.84LGDD308 pKa = 3.23RR309 pKa = 11.84SRR311 pKa = 11.84YY312 pKa = 8.99LALLEE317 pKa = 4.48SPEE320 pKa = 4.06LMEE323 pKa = 5.0FAPANYY329 pKa = 9.06PLLFSYY335 pKa = 11.18AMGVGSVQDD344 pKa = 3.78PLIRR348 pKa = 11.84NYY350 pKa = 10.36QFGRR354 pKa = 11.84NFLNTSYY361 pKa = 10.47FQYY364 pKa = 10.83GVEE367 pKa = 4.02TAMKK371 pKa = 9.63HH372 pKa = 5.28QGTVDD377 pKa = 3.31PKK379 pKa = 10.01FASEE383 pKa = 5.07LGITDD388 pKa = 3.81EE389 pKa = 4.55DD390 pKa = 3.97RR391 pKa = 11.84VDD393 pKa = 3.09IMQSVEE399 pKa = 3.63KK400 pKa = 10.16HH401 pKa = 5.22ISGKK405 pKa = 10.66AGDD408 pKa = 5.48DD409 pKa = 3.06ISQPRR414 pKa = 11.84SAFTMSLNRR423 pKa = 11.84SAFITNNNPQDD434 pKa = 3.57LSGARR439 pKa = 11.84LSNYY443 pKa = 7.13EE444 pKa = 4.09QGWSGIDD451 pKa = 3.25QDD453 pKa = 4.19EE454 pKa = 4.52TRR456 pKa = 11.84DD457 pKa = 3.85TLPEE461 pKa = 3.98STMHH465 pKa = 7.05RR466 pKa = 11.84FQNIDD471 pKa = 3.42STNSDD476 pKa = 3.53HH477 pKa = 7.7NEE479 pKa = 3.52LQMPEE484 pKa = 4.26FEE486 pKa = 4.92NDD488 pKa = 2.86INPFNHH494 pKa = 6.44PRR496 pKa = 11.84FTARR500 pKa = 11.84APLIPEE506 pKa = 4.68ISHH509 pKa = 4.62QTPTIRR515 pKa = 11.84MNRR518 pKa = 11.84NVNIRR523 pKa = 11.84DD524 pKa = 3.35STRR527 pKa = 11.84DD528 pKa = 3.33DD529 pKa = 3.5RR530 pKa = 11.84QDD532 pKa = 3.38ANEE535 pKa = 4.65DD536 pKa = 3.45RR537 pKa = 11.84SSNIPDD543 pKa = 5.7DD544 pKa = 3.92ILGDD548 pKa = 3.81LDD550 pKa = 3.62NN551 pKa = 5.04

Molecular weight: 62.56 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|D7US59|D7US59_9MONO Fusion glycoprotein F0 OS=Human parainfluenza virus 4a OX=11224 GN=F PE=3 SV=1
MM1 pKa = 7.83APTQSKK7 pKa = 9.29VRR9 pKa = 11.84IHH11 pKa = 6.28NLAEE15 pKa = 3.96AHH17 pKa = 6.32EE18 pKa = 4.38KK19 pKa = 9.02TLRR22 pKa = 11.84AFPIEE27 pKa = 4.22VEE29 pKa = 4.19QNPEE33 pKa = 3.92GKK35 pKa = 10.09KK36 pKa = 10.65LLVKK40 pKa = 9.78QIRR43 pKa = 11.84IRR45 pKa = 11.84TLGHH49 pKa = 7.03ADD51 pKa = 3.44HH52 pKa = 7.2SNDD55 pKa = 4.42SICFLNTYY63 pKa = 10.15GFIKK67 pKa = 10.29EE68 pKa = 4.43AVSQTEE74 pKa = 4.0FMRR77 pKa = 11.84AGQKK81 pKa = 9.94SEE83 pKa = 4.21SKK85 pKa = 9.15NTLTACMLPFGPGPNIGSPQKK106 pKa = 9.18MLEE109 pKa = 3.87YY110 pKa = 11.0AEE112 pKa = 5.26DD113 pKa = 3.35IKK115 pKa = 11.28IHH117 pKa = 4.44VRR119 pKa = 11.84KK120 pKa = 7.77TAGCKK125 pKa = 7.59EE126 pKa = 4.1QIVFSLDD133 pKa = 2.84RR134 pKa = 11.84TPQVFRR140 pKa = 11.84GFQFPRR146 pKa = 11.84DD147 pKa = 3.45RR148 pKa = 11.84YY149 pKa = 10.77ACVPSDD155 pKa = 4.69KK156 pKa = 10.65YY157 pKa = 10.9IKK159 pKa = 10.85SPGKK163 pKa = 10.15LVAGPNYY170 pKa = 10.28CYY172 pKa = 10.4IITFLSLTFCPSSQKK187 pKa = 10.46FKK189 pKa = 11.11VPRR192 pKa = 11.84PVLNFRR198 pKa = 11.84STRR201 pKa = 11.84MRR203 pKa = 11.84GIHH206 pKa = 6.45LEE208 pKa = 4.08IIMKK212 pKa = 8.14ITCSEE217 pKa = 3.82NSPIRR222 pKa = 11.84KK223 pKa = 7.65TLITDD228 pKa = 3.67DD229 pKa = 4.8LEE231 pKa = 4.72NGPKK235 pKa = 10.12ASVWIHH241 pKa = 6.15LCNLYY246 pKa = 10.41KK247 pKa = 10.58GRR249 pKa = 11.84NPIKK253 pKa = 10.21IYY255 pKa = 10.85DD256 pKa = 3.67EE257 pKa = 5.13AYY259 pKa = 10.03FAEE262 pKa = 4.88KK263 pKa = 9.48CKK265 pKa = 10.7QMLLSVGISDD275 pKa = 4.1LWGPTIAVHH284 pKa = 6.93ANGKK288 pKa = 8.77IPKK291 pKa = 9.53SASLYY296 pKa = 9.41FNSRR300 pKa = 11.84GWALHH305 pKa = 6.57PIADD309 pKa = 4.8ASPTMAKK316 pKa = 9.53QLWSIGCEE324 pKa = 3.46IMEE327 pKa = 4.62VNAILQGSDD336 pKa = 3.13YY337 pKa = 10.83SALVDD342 pKa = 4.11HH343 pKa = 7.56PDD345 pKa = 3.12VIYY348 pKa = 10.6RR349 pKa = 11.84KK350 pKa = 9.65IRR352 pKa = 11.84IDD354 pKa = 3.53PAKK357 pKa = 10.14KK358 pKa = 10.03QYY360 pKa = 11.02AHH362 pKa = 6.66SKK364 pKa = 8.54WNPFKK369 pKa = 10.84KK370 pKa = 10.31AISMPNLTDD379 pKa = 4.26DD380 pKa = 4.92SII382 pKa = 5.67

Molecular weight: 43.12 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

4957

229

2279

708.1

80.26

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.185 ± 0.63

2.038 ± 0.329

5.487 ± 0.479

5.144 ± 0.51

3.651 ± 0.564

4.6 ± 0.442

2.098 ± 0.262

8.856 ± 0.747

5.709 ± 0.427

10.874 ± 0.945

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.098 ± 0.255

6.617 ± 0.284

4.741 ± 0.367

4.66 ± 0.385

4.882 ± 0.455

7.888 ± 0.308

6.415 ± 0.709

4.438 ± 0.307

1.089 ± 0.275

3.53 ± 0.511
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski