Cercopithecine alphaherpesvirus 2

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus

Average proteome isoelectric point is 7.14

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 73 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q5Y0V0|Q5Y0V0_9ALPH UL3 OS=Cercopithecine alphaherpesvirus 2 OX=10317 GN=UL3 PE=3 SV=1
MM1 pKa = 7.22SASASSATIAYY12 pKa = 8.63SLHH15 pKa = 5.89GAATSSACVLPDD27 pKa = 3.52AEE29 pKa = 4.17QVVCAFEE36 pKa = 4.29SGTRR40 pKa = 11.84AIASRR45 pKa = 11.84GCLRR49 pKa = 11.84HH50 pKa = 6.6DD51 pKa = 3.74ALSRR55 pKa = 11.84GAVVVRR61 pKa = 11.84QTPVGLLVMVDD72 pKa = 4.01CRR74 pKa = 11.84TEE76 pKa = 3.92FCAYY80 pKa = 9.89RR81 pKa = 11.84FVGRR85 pKa = 11.84SEE87 pKa = 3.96RR88 pKa = 11.84QRR90 pKa = 11.84LEE92 pKa = 4.0RR93 pKa = 11.84WWDD96 pKa = 3.52TTLCAYY102 pKa = 9.69PFDD105 pKa = 3.98SWVSSTRR112 pKa = 11.84GEE114 pKa = 4.3SARR117 pKa = 11.84SPTAGIATVVWGEE130 pKa = 3.7DD131 pKa = 3.15SIYY134 pKa = 9.94ITVTVYY140 pKa = 10.46GSPPEE145 pKa = 4.56GEE147 pKa = 4.34AGAPPRR153 pKa = 11.84LPPPPGDD160 pKa = 4.34APDD163 pKa = 4.36APSPPAVSPASAEE176 pKa = 3.93TGAAADD182 pKa = 4.17LLVEE186 pKa = 4.19VMKK189 pKa = 10.32EE190 pKa = 3.84IQLSPTLGFGPCDD203 pKa = 3.21AA204 pKa = 5.68

Molecular weight: 21.32 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q5Y0V1|Q5Y0V1_9ALPH Uracil-DNA glycosylase OS=Cercopithecine alphaherpesvirus 2 OX=10317 GN=UL2 PE=3 SV=1
MM1 pKa = 7.16SAVGAGAVPSTLAVLASWGWAFAPHH26 pKa = 7.31DD27 pKa = 4.55GPPARR32 pKa = 11.84AAEE35 pKa = 4.6APASPAPEE43 pKa = 4.6APTGHH48 pKa = 7.13PVPPRR53 pKa = 11.84ADD55 pKa = 3.28DD56 pKa = 3.68RR57 pKa = 11.84APPGVRR63 pKa = 11.84APDD66 pKa = 4.15PDD68 pKa = 3.73HH69 pKa = 6.93VAFDD73 pKa = 3.73TMFMVSSVDD82 pKa = 3.32EE83 pKa = 4.19LGRR86 pKa = 11.84RR87 pKa = 11.84QLTDD91 pKa = 3.82TIRR94 pKa = 11.84KK95 pKa = 9.09DD96 pKa = 3.43LRR98 pKa = 11.84LSLVNLAIACTKK110 pKa = 9.72TSSFSGTAGRR120 pKa = 11.84ARR122 pKa = 11.84PRR124 pKa = 11.84ARR126 pKa = 11.84HH127 pKa = 5.4GPGHH131 pKa = 6.83RR132 pKa = 11.84EE133 pKa = 4.0PPSHH137 pKa = 7.31KK138 pKa = 9.61SLQMFVLCQRR148 pKa = 11.84PDD150 pKa = 2.99ATRR153 pKa = 11.84VRR155 pKa = 11.84DD156 pKa = 3.44QLRR159 pKa = 11.84AVIASRR165 pKa = 11.84KK166 pKa = 6.69PRR168 pKa = 11.84KK169 pKa = 9.7YY170 pKa = 8.92YY171 pKa = 9.88TRR173 pKa = 11.84SSDD176 pKa = 3.26GRR178 pKa = 11.84ISPAVPVFVHH188 pKa = 6.3EE189 pKa = 4.83FVSDD193 pKa = 3.9APVHH197 pKa = 4.4VHH199 pKa = 6.69RR200 pKa = 11.84DD201 pKa = 3.43NVIAPVVPRR210 pKa = 11.84RR211 pKa = 11.84RR212 pKa = 11.84TSTRR216 pKa = 11.84LADD219 pKa = 4.21PASEE223 pKa = 5.39DD224 pKa = 3.13PWQQ227 pKa = 3.83

Molecular weight: 24.57 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

73

0

73

37766

77

3070

517.3

55.38

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

15.946 ± 0.576

1.729 ± 0.099

5.33 ± 0.168

5.452 ± 0.167

3.344 ± 0.186

8.092 ± 0.18

2.29 ± 0.119

2.063 ± 0.153

1.157 ± 0.124

9.956 ± 0.229

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.395 ± 0.107

1.673 ± 0.16

9.286 ± 0.462

2.261 ± 0.131

9.744 ± 0.215

5.108 ± 0.18

4.753 ± 0.153

6.919 ± 0.229

1.123 ± 0.066

2.378 ± 0.136
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski