Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria;

Average proteome isoelectric point is 6.73

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 20406 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A091D9Y9|A0A091D9Y9_FUKDA Protein FAM72A OS=Fukomys damarensis OX=885580 GN=H920_18942 PE=3 SV=1
MM1 pKa = 7.29AHH3 pKa = 7.21EE4 pKa = 4.89KK5 pKa = 10.57PDD7 pKa = 3.88FQVLEE12 pKa = 4.22AVKK15 pKa = 10.53SEE17 pKa = 4.02SSDD20 pKa = 3.59YY21 pKa = 11.67SCMDD25 pKa = 5.21DD26 pKa = 4.53EE27 pKa = 7.11DD28 pKa = 5.29DD29 pKa = 4.65PLWSNTCFHH38 pKa = 6.81NRR40 pKa = 11.84RR41 pKa = 11.84AMWVCDD47 pKa = 4.26DD48 pKa = 5.08NDD50 pKa = 4.58DD51 pKa = 4.85FDD53 pKa = 5.47IDD55 pKa = 3.98HH56 pKa = 6.9MNQSSCDD63 pKa = 3.43NEE65 pKa = 4.27MEE67 pKa = 4.44QEE69 pKa = 4.37SNDD72 pKa = 3.66TDD74 pKa = 3.61TGNADD79 pKa = 4.28PLNSDD84 pKa = 3.78DD85 pKa = 5.5KK86 pKa = 11.38EE87 pKa = 4.16NSSVNTYY94 pKa = 8.07LTSS97 pKa = 3.26

Molecular weight: 11.11 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A091CYA5|A0A091CYA5_FUKDA Dimethylaniline monooxygenase [N-oxide-forming] OS=Fukomys damarensis OX=885580 GN=H920_15714 PE=3 SV=1
MM1 pKa = 7.61ARR3 pKa = 11.84GLHH6 pKa = 5.64RR7 pKa = 11.84RR8 pKa = 11.84GGKK11 pKa = 8.68PRR13 pKa = 11.84QVLALLNSRR22 pKa = 11.84ANSVSKK28 pKa = 10.57ASRR31 pKa = 11.84MRR33 pKa = 11.84QGRR36 pKa = 11.84SRR38 pKa = 11.84SVGTRR43 pKa = 11.84RR44 pKa = 11.84RR45 pKa = 11.84SPAPRR50 pKa = 11.84VLTCKK55 pKa = 10.2PPAARR60 pKa = 11.84RR61 pKa = 11.84GRR63 pKa = 11.84KK64 pKa = 9.16RR65 pKa = 11.84GPAKK69 pKa = 10.27QGLNRR74 pKa = 11.84STRR77 pKa = 11.84GRR79 pKa = 11.84GAQAPRR85 pKa = 11.84KK86 pKa = 9.96GMAEE90 pKa = 4.06SPAKK94 pKa = 10.31RR95 pKa = 11.84GVRR98 pKa = 11.84KK99 pKa = 8.96PRR101 pKa = 11.84CYY103 pKa = 10.64LRR105 pKa = 11.84GGG107 pKa = 3.45

Molecular weight: 11.73 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

20406

0

20406

10132680

22

30784

496.6

55.37

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.93 ± 0.017

2.316 ± 0.016

4.755 ± 0.013

7.089 ± 0.031

3.718 ± 0.014

6.437 ± 0.023

2.65 ± 0.011

4.363 ± 0.016

5.639 ± 0.024

10.161 ± 0.026

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.204 ± 0.009

3.489 ± 0.013

6.054 ± 0.027

4.763 ± 0.02

5.599 ± 0.016

8.348 ± 0.023

5.387 ± 0.014

6.231 ± 0.019

1.224 ± 0.006

2.645 ± 0.011
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski