Amino acid dipepetide frequency for Slackia exigua (strain ATCC 700122 / DSM 15923 / CIP 105133 / JCM 11022 / KCTC 5966 / S-7)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.511AlaAla: 15.511 ± 0.219	2.617AlaCys: 2.617 ± 0.073	7.409AlaAsp: 7.409 ± 0.134	6.451AlaGlu: 6.451 ± 0.108	5.126AlaPhe: 5.126 ± 0.108	9.911AlaGly: 9.911 ± 0.15	2.52AlaHis: 2.52 ± 0.059	5.797AlaIle: 5.797 ± 0.103	4.068AlaLys: 4.068 ± 0.085	11.587AlaLeu: 11.587 ± 0.166	3.49AlaMet: 3.49 ± 0.076	2.53AlaAsn: 2.53 ± 0.063	4.595AlaPro: 4.595 ± 0.108	3.559AlaGln: 3.559 ± 0.077	8.164AlaArg: 8.164 ± 0.156	8.66AlaSer: 8.66 ± 0.151	5.526AlaThr: 5.526 ± 0.117	8.782AlaVal: 8.782 ± 0.122	1.278AlaTrp: 1.278 ± 0.054	3.287AlaTyr: 3.287 ± 0.073	0.0AlaXaa: 0.0 ± 0.0
Cys	2.018CysAla: 2.018 ± 0.069	0.283CysCys: 0.283 ± 0.02	1.028CysAsp: 1.028 ± 0.041	0.917CysGlu: 0.917 ± 0.042	0.515CysPhe: 0.515 ± 0.028	1.739CysGly: 1.739 ± 0.055	0.313CysHis: 0.313 ± 0.029	0.923CysIle: 0.923 ± 0.044	0.454CysLys: 0.454 ± 0.03	1.216CysLeu: 1.216 ± 0.046	0.478CysMet: 0.478 ± 0.029	0.348CysAsn: 0.348 ± 0.024	0.694CysPro: 0.694 ± 0.04	0.294CysGln: 0.294 ± 0.023	0.922CysArg: 0.922 ± 0.045	0.821CysSer: 0.821 ± 0.032	0.811CysThr: 0.811 ± 0.034	1.24CysVal: 1.24 ± 0.056	0.125CysTrp: 0.125 ± 0.013	0.364CysTyr: 0.364 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	9.919AspAla: 9.919 ± 0.173	0.71AspCys: 0.71 ± 0.033	4.209AspAsp: 4.209 ± 0.092	5.174AspGlu: 5.174 ± 0.101	2.367AspPhe: 2.367 ± 0.057	5.803AspGly: 5.803 ± 0.146	0.988AspHis: 0.988 ± 0.045	3.458AspIle: 3.458 ± 0.066	1.828AspLys: 1.828 ± 0.059	5.289AspLeu: 5.289 ± 0.101	1.712AspMet: 1.712 ± 0.052	1.222AspAsn: 1.222 ± 0.05	2.952AspPro: 2.952 ± 0.075	1.391AspGln: 1.391 ± 0.042	3.755AspArg: 3.755 ± 0.077	3.075AspSer: 3.075 ± 0.075	2.633AspThr: 2.633 ± 0.067	5.359AspVal: 5.359 ± 0.099	0.688AspTrp: 0.688 ± 0.035	1.806AspTyr: 1.806 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	7.492GluAla: 7.492 ± 0.126	0.715GluCys: 0.715 ± 0.029	3.662GluAsp: 3.662 ± 0.075	4.358GluGlu: 4.358 ± 0.104	2.024GluPhe: 2.024 ± 0.058	5.428GluGly: 5.428 ± 0.104	1.339GluHis: 1.339 ± 0.058	2.919GluIle: 2.919 ± 0.076	2.691GluLys: 2.691 ± 0.075	5.188GluLeu: 5.188 ± 0.085	1.633GluMet: 1.633 ± 0.054	1.937GluAsn: 1.937 ± 0.055	2.407GluPro: 2.407 ± 0.063	1.731GluGln: 1.731 ± 0.052	4.9GluArg: 4.9 ± 0.109	3.573GluSer: 3.573 ± 0.085	3.276GluThr: 3.276 ± 0.062	3.997GluVal: 3.997 ± 0.09	0.572GluTrp: 0.572 ± 0.03	1.632GluTyr: 1.632 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	4.535PheAla: 4.535 ± 0.098	0.628PheCys: 0.628 ± 0.031	3.11PheAsp: 3.11 ± 0.087	2.422PheGlu: 2.422 ± 0.063	1.576PhePhe: 1.576 ± 0.061	3.73PheGly: 3.73 ± 0.096	0.642PheHis: 0.642 ± 0.029	1.969PheIle: 1.969 ± 0.066	1.331PheLys: 1.331 ± 0.049	3.173PheLeu: 3.173 ± 0.082	1.1PheMet: 1.1 ± 0.048	0.96PheAsn: 0.96 ± 0.037	1.418PhePro: 1.418 ± 0.052	0.901PheGln: 0.901 ± 0.042	1.733PheArg: 1.733 ± 0.051	2.731PheSer: 2.731 ± 0.065	1.853PheThr: 1.853 ± 0.069	3.292PheVal: 3.292 ± 0.086	0.465PheTrp: 0.465 ± 0.027	1.107PheTyr: 1.107 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	9.215GlyAla: 9.215 ± 0.169	1.562GlyCys: 1.562 ± 0.052	4.663GlyAsp: 4.663 ± 0.11	4.468GlyGlu: 4.468 ± 0.084	3.679GlyPhe: 3.679 ± 0.073	6.677GlyGly: 6.677 ± 0.136	1.557GlyHis: 1.557 ± 0.051	5.841GlyIle: 5.841 ± 0.107	3.534GlyLys: 3.534 ± 0.088	7.043GlyLeu: 7.043 ± 0.125	2.867GlyMet: 2.867 ± 0.081	2.288GlyAsn: 2.288 ± 0.074	2.266GlyPro: 2.266 ± 0.053	1.951GlyGln: 1.951 ± 0.06	5.472GlyArg: 5.472 ± 0.119	5.846GlySer: 5.846 ± 0.118	5.128GlyThr: 5.128 ± 0.131	6.391GlyVal: 6.391 ± 0.109	1.085GlyTrp: 1.085 ± 0.06	2.571GlyTyr: 2.571 ± 0.067	0.0GlyXaa: 0.0 ± 0.0
His	2.699HisAla: 2.699 ± 0.071	0.278HisCys: 0.278 ± 0.021	1.406HisAsp: 1.406 ± 0.042	1.293HisGlu: 1.293 ± 0.043	0.615HisPhe: 0.615 ± 0.033	1.822HisGly: 1.822 ± 0.06	0.422HisHis: 0.422 ± 0.027	0.933HisIle: 0.933 ± 0.037	0.46HisLys: 0.46 ± 0.027	1.431HisLeu: 1.431 ± 0.054	0.496HisMet: 0.496 ± 0.034	0.417HisAsn: 0.417 ± 0.027	1.187HisPro: 1.187 ± 0.044	0.394HisGln: 0.394 ± 0.024	1.274HisArg: 1.274 ± 0.043	1.018HisSer: 1.018 ± 0.038	0.906HisThr: 0.906 ± 0.042	1.632HisVal: 1.632 ± 0.051	0.182HisTrp: 0.182 ± 0.018	0.498HisTyr: 0.498 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.341IleAla: 7.341 ± 0.121	0.865IleCys: 0.865 ± 0.044	4.135IleAsp: 4.135 ± 0.079	3.964IleGlu: 3.964 ± 0.082	1.595IlePhe: 1.595 ± 0.062	4.823IleGly: 4.823 ± 0.106	0.87IleHis: 0.87 ± 0.035	2.405IleIle: 2.405 ± 0.071	1.725IleLys: 1.725 ± 0.055	4.086IleLeu: 4.086 ± 0.103	1.452IleMet: 1.452 ± 0.051	1.265IleAsn: 1.265 ± 0.043	2.59IlePro: 2.59 ± 0.065	1.18IleGln: 1.18 ± 0.049	2.784IleArg: 2.784 ± 0.067	3.112IleSer: 3.112 ± 0.075	2.47IleThr: 2.47 ± 0.077	5.223IleVal: 5.223 ± 0.118	0.457IleTrp: 0.457 ± 0.028	1.206IleTyr: 1.206 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.326LysAla: 4.326 ± 0.092	0.316LysCys: 0.316 ± 0.025	2.407LysAsp: 2.407 ± 0.088	2.397LysGlu: 2.397 ± 0.075	0.862LysPhe: 0.862 ± 0.038	3.018LysGly: 3.018 ± 0.08	0.678LysHis: 0.678 ± 0.039	1.671LysIle: 1.671 ± 0.067	2.018LysLys: 2.018 ± 0.074	2.765LysLeu: 2.765 ± 0.073	0.949LysMet: 0.949 ± 0.041	1.197LysAsn: 1.197 ± 0.055	1.722LysPro: 1.722 ± 0.06	1.007LysGln: 1.007 ± 0.043	2.677LysArg: 2.677 ± 0.072	2.059LysSer: 2.059 ± 0.063	2.467LysThr: 2.467 ± 0.073	2.674LysVal: 2.674 ± 0.072	0.311LysTrp: 0.311 ± 0.025	0.848LysTyr: 0.848 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	10.826LeuAla: 10.826 ± 0.168	1.243LeuCys: 1.243 ± 0.045	5.836LeuAsp: 5.836 ± 0.096	5.27LeuGlu: 5.27 ± 0.112	3.466LeuPhe: 3.466 ± 0.09	6.963LeuGly: 6.963 ± 0.128	1.592LeuHis: 1.592 ± 0.051	4.454LeuIle: 4.454 ± 0.124	3.213LeuLys: 3.213 ± 0.08	7.471LeuLeu: 7.471 ± 0.151	2.44LeuMet: 2.44 ± 0.07	2.075LeuAsn: 2.075 ± 0.057	4.136LeuPro: 4.136 ± 0.083	1.837LeuGln: 1.837 ± 0.056	5.132LeuArg: 5.132 ± 0.121	6.707LeuSer: 6.707 ± 0.112	4.323LeuThr: 4.323 ± 0.101	7.258LeuVal: 7.258 ± 0.119	0.811LeuTrp: 0.811 ± 0.035	2.169LeuTyr: 2.169 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.892MetAla: 2.892 ± 0.073	0.332MetCys: 0.332 ± 0.023	1.61MetAsp: 1.61 ± 0.056	1.469MetGlu: 1.469 ± 0.051	0.816MetPhe: 0.816 ± 0.039	2.316MetGly: 2.316 ± 0.061	0.693MetHis: 0.693 ± 0.035	1.308MetIle: 1.308 ± 0.049	1.241MetLys: 1.241 ± 0.043	2.873MetLeu: 2.873 ± 0.079	0.761MetMet: 0.761 ± 0.037	1.042MetAsn: 1.042 ± 0.046	1.701MetPro: 1.701 ± 0.057	0.901MetGln: 0.901 ± 0.038	2.432MetArg: 2.432 ± 0.082	1.839MetSer: 1.839 ± 0.053	1.648MetThr: 1.648 ± 0.054	1.826MetVal: 1.826 ± 0.058	0.244MetTrp: 0.244 ± 0.02	0.588MetTyr: 0.588 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	3.366AsnAla: 3.366 ± 0.078	0.335AsnCys: 0.335 ± 0.024	1.73AsnAsp: 1.73 ± 0.054	1.619AsnGlu: 1.619 ± 0.043	0.813AsnPhe: 0.813 ± 0.041	2.388AsnGly: 2.388 ± 0.068	0.482AsnHis: 0.482 ± 0.029	1.358AsnIle: 1.358 ± 0.043	0.737AsnLys: 0.737 ± 0.037	2.244AsnLeu: 2.244 ± 0.067	0.585AsnMet: 0.585 ± 0.031	0.618AsnAsn: 0.618 ± 0.034	1.717AsnPro: 1.717 ± 0.056	0.708AsnGln: 0.708 ± 0.034	1.535AsnArg: 1.535 ± 0.052	1.127AsnSer: 1.127 ± 0.045	1.236AsnThr: 1.236 ± 0.051	2.214AsnVal: 2.214 ± 0.064	0.305AsnTrp: 0.305 ± 0.022	0.742AsnTyr: 0.742 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	4.993ProAla: 4.993 ± 0.103	0.615ProCys: 0.615 ± 0.031	3.154ProAsp: 3.154 ± 0.073	3.158ProGlu: 3.158 ± 0.066	1.828ProPhe: 1.828 ± 0.053	3.243ProGly: 3.243 ± 0.079	0.972ProHis: 0.972 ± 0.037	2.149ProIle: 2.149 ± 0.052	1.497ProLys: 1.497 ± 0.05	3.751ProLeu: 3.751 ± 0.079	0.983ProMet: 0.983 ± 0.042	1.086ProAsn: 1.086 ± 0.04	1.145ProPro: 1.145 ± 0.04	1.138ProGln: 1.138 ± 0.044	2.407ProArg: 2.407 ± 0.072	3.099ProSer: 3.099 ± 0.076	2.237ProThr: 2.237 ± 0.061	3.207ProVal: 3.207 ± 0.083	0.451ProTrp: 0.451 ± 0.027	1.349ProTyr: 1.349 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	3.056GlnAla: 3.056 ± 0.076	0.272GlnCys: 0.272 ± 0.02	1.507GlnAsp: 1.507 ± 0.042	1.611GlnGlu: 1.611 ± 0.061	0.762GlnPhe: 0.762 ± 0.034	2.179GlnGly: 2.179 ± 0.059	0.462GlnHis: 0.462 ± 0.031	1.331GlnIle: 1.331 ± 0.052	1.08GlnLys: 1.08 ± 0.045	1.975GlnLeu: 1.975 ± 0.06	0.762GlnMet: 0.762 ± 0.04	0.748GlnAsn: 0.748 ± 0.036	1.033GlnPro: 1.033 ± 0.05	0.759GlnGln: 0.759 ± 0.044	1.69GlnArg: 1.69 ± 0.06	1.333GlnSer: 1.333 ± 0.048	1.448GlnThr: 1.448 ± 0.057	2.056GlnVal: 2.056 ± 0.055	0.25GlnTrp: 0.25 ± 0.024	0.634GlnTyr: 0.634 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	7.109ArgAla: 7.109 ± 0.145	0.947ArgCys: 0.947 ± 0.042	3.659ArgAsp: 3.659 ± 0.085	4.008ArgGlu: 4.008 ± 0.081	2.751ArgPhe: 2.751 ± 0.071	4.347ArgGly: 4.347 ± 0.093	1.316ArgHis: 1.316 ± 0.05	4.345ArgIle: 4.345 ± 0.096	2.459ArgLys: 2.459 ± 0.067	5.806ArgLeu: 5.806 ± 0.122	2.426ArgMet: 2.426 ± 0.061	1.837ArgAsn: 1.837 ± 0.059	2.59ArgPro: 2.59 ± 0.076	1.526ArgGln: 1.526 ± 0.051	5.365ArgArg: 5.365 ± 0.141	3.83ArgSer: 3.83 ± 0.093	3.463ArgThr: 3.463 ± 0.076	4.429ArgVal: 4.429 ± 0.096	0.552ArgTrp: 0.552 ± 0.029	1.763ArgTyr: 1.763 ± 0.053	0.0ArgXaa: 0.0 ± 0.0
Ser	7.005SerAla: 7.005 ± 0.162	1.05SerCys: 1.05 ± 0.044	3.918SerAsp: 3.918 ± 0.091	3.442SerGlu: 3.442 ± 0.067	2.935SerPhe: 2.935 ± 0.064	5.901SerGly: 5.901 ± 0.115	1.26SerHis: 1.26 ± 0.045	3.657SerIle: 3.657 ± 0.083	2.247SerLys: 2.247 ± 0.073	5.487SerLeu: 5.487 ± 0.093	1.953SerMet: 1.953 ± 0.053	1.589SerAsn: 1.589 ± 0.054	2.484SerPro: 2.484 ± 0.078	1.605SerGln: 1.605 ± 0.045	3.795SerArg: 3.795 ± 0.098	4.88SerSer: 4.88 ± 0.128	3.301SerThr: 3.301 ± 0.073	4.761SerVal: 4.761 ± 0.095	0.848SerTrp: 0.848 ± 0.035	2.011SerTyr: 2.011 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	5.189ThrAla: 5.189 ± 0.124	0.835ThrCys: 0.835 ± 0.039	3.116ThrAsp: 3.116 ± 0.082	2.557ThrGlu: 2.557 ± 0.068	2.161ThrPhe: 2.161 ± 0.065	4.653ThrGly: 4.653 ± 0.109	1.161ThrHis: 1.161 ± 0.042	3.026ThrIle: 3.026 ± 0.082	1.79ThrLys: 1.79 ± 0.055	4.952ThrLeu: 4.952 ± 0.1	1.412ThrMet: 1.412 ± 0.043	1.352ThrAsn: 1.352 ± 0.062	2.675ThrPro: 2.675 ± 0.082	1.289ThrGln: 1.289 ± 0.052	2.728ThrArg: 2.728 ± 0.062	3.03ThrSer: 3.03 ± 0.072	2.767ThrThr: 2.767 ± 0.09	4.606ThrVal: 4.606 ± 0.122	0.615ThrTrp: 0.615 ± 0.035	1.648ThrTyr: 1.648 ± 0.069	0.0ThrXaa: 0.0 ± 0.0
Val	8.997ValAla: 8.997 ± 0.133	1.323ValCys: 1.323 ± 0.058	5.17ValAsp: 5.17 ± 0.09	4.664ValGlu: 4.664 ± 0.08	3.268ValPhe: 3.268 ± 0.086	5.936ValGly: 5.936 ± 0.124	1.396ValHis: 1.396 ± 0.044	4.177ValIle: 4.177 ± 0.088	2.829ValLys: 2.829 ± 0.078	7.272ValLeu: 7.272 ± 0.132	2.032ValMet: 2.032 ± 0.064	2.125ValAsn: 2.125 ± 0.065	3.629ValPro: 3.629 ± 0.085	1.747ValGln: 1.747 ± 0.049	5.098ValArg: 5.098 ± 0.099	5.409ValSer: 5.409 ± 0.101	4.054ValThr: 4.054 ± 0.091	6.869ValVal: 6.869 ± 0.141	0.753ValTrp: 0.753 ± 0.03	1.973ValTyr: 1.973 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	1.04TrpAla: 1.04 ± 0.046	0.16TrpCys: 0.16 ± 0.017	0.625TrpAsp: 0.625 ± 0.033	0.561TrpGlu: 0.561 ± 0.035	0.443TrpPhe: 0.443 ± 0.027	0.775TrpGly: 0.775 ± 0.038	0.217TrpHis: 0.217 ± 0.018	0.631TrpIle: 0.631 ± 0.035	0.422TrpLys: 0.422 ± 0.028	0.982TrpLeu: 0.982 ± 0.044	0.351TrpMet: 0.351 ± 0.025	0.446TrpAsn: 0.446 ± 0.027	0.354TrpPro: 0.354 ± 0.022	0.362TrpGln: 0.362 ± 0.031	0.686TrpArg: 0.686 ± 0.037	0.577TrpSer: 0.577 ± 0.037	0.557TrpThr: 0.557 ± 0.03	0.718TrpVal: 0.718 ± 0.031	0.12TrpTrp: 0.12 ± 0.014	0.348TrpTyr: 0.348 ± 0.041	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.339TyrAla: 3.339 ± 0.082	0.416TyrCys: 0.416 ± 0.027	1.984TyrAsp: 1.984 ± 0.06	1.67TyrGlu: 1.67 ± 0.052	1.074TyrPhe: 1.074 ± 0.045	2.452TyrGly: 2.452 ± 0.06	0.484TyrHis: 0.484 ± 0.026	1.194TyrIle: 1.194 ± 0.046	0.745TyrLys: 0.745 ± 0.037	2.634TyrLeu: 2.634 ± 0.063	0.648TyrMet: 0.648 ± 0.032	0.778TyrAsn: 0.778 ± 0.041	1.167TyrPro: 1.167 ± 0.044	0.666TyrGln: 0.666 ± 0.035	1.976TyrArg: 1.976 ± 0.06	1.403TyrSer: 1.403 ± 0.051	1.458TyrThr: 1.458 ± 0.055	2.192TyrVal: 2.192 ± 0.062	0.264TyrTrp: 0.264 ± 0.021	0.876TyrTyr: 0.876 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2027 proteins (632442 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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