Amino acid dipepetide frequency for Mucilaginibacter xinganensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.208AlaAla: 7.208 ± 0.09	0.72AlaCys: 0.72 ± 0.023	4.817AlaAsp: 4.817 ± 0.06	4.341AlaGlu: 4.341 ± 0.059	3.696AlaPhe: 3.696 ± 0.051	6.381AlaGly: 6.381 ± 0.077	1.373AlaHis: 1.373 ± 0.033	5.8AlaIle: 5.8 ± 0.074	4.862AlaLys: 4.862 ± 0.063	7.146AlaLeu: 7.146 ± 0.091	1.782AlaMet: 1.782 ± 0.034	3.877AlaAsn: 3.877 ± 0.058	2.546AlaPro: 2.546 ± 0.049	2.887AlaGln: 2.887 ± 0.043	2.523AlaArg: 2.523 ± 0.044	4.451AlaSer: 4.451 ± 0.062	4.278AlaThr: 4.278 ± 0.063	5.296AlaVal: 5.296 ± 0.074	0.809AlaTrp: 0.809 ± 0.023	2.899AlaTyr: 2.899 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.563CysAla: 0.563 ± 0.02	0.156CysCys: 0.156 ± 0.01	0.421CysAsp: 0.421 ± 0.016	0.383CysGlu: 0.383 ± 0.016	0.473CysPhe: 0.473 ± 0.017	0.674CysGly: 0.674 ± 0.021	0.205CysHis: 0.205 ± 0.013	0.643CysIle: 0.643 ± 0.022	0.513CysLys: 0.513 ± 0.019	0.824CysLeu: 0.824 ± 0.022	0.205CysMet: 0.205 ± 0.011	0.397CysAsn: 0.397 ± 0.017	0.358CysPro: 0.358 ± 0.017	0.219CysGln: 0.219 ± 0.012	0.343CysArg: 0.343 ± 0.015	0.534CysSer: 0.534 ± 0.019	0.44CysThr: 0.44 ± 0.017	0.47CysVal: 0.47 ± 0.017	0.104CysTrp: 0.104 ± 0.008	0.316CysTyr: 0.316 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.139AspAla: 4.139 ± 0.053	0.41AspCys: 0.41 ± 0.016	2.874AspAsp: 2.874 ± 0.046	3.423AspGlu: 3.423 ± 0.057	3.033AspPhe: 3.033 ± 0.052	3.787AspGly: 3.787 ± 0.065	1.061AspHis: 1.061 ± 0.026	3.861AspIle: 3.861 ± 0.051	3.974AspLys: 3.974 ± 0.054	4.755AspLeu: 4.755 ± 0.054	1.15AspMet: 1.15 ± 0.029	2.862AspAsn: 2.862 ± 0.05	2.145AspPro: 2.145 ± 0.036	1.751AspGln: 1.751 ± 0.035	2.004AspArg: 2.004 ± 0.039	2.955AspSer: 2.955 ± 0.044	2.785AspThr: 2.785 ± 0.047	3.432AspVal: 3.432 ± 0.05	0.745AspTrp: 0.745 ± 0.024	2.567AspTyr: 2.567 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	3.999GluAla: 3.999 ± 0.057	0.297GluCys: 0.297 ± 0.013	2.458GluAsp: 2.458 ± 0.048	3.079GluGlu: 3.079 ± 0.058	2.323GluPhe: 2.323 ± 0.039	3.064GluGly: 3.064 ± 0.051	1.054GluHis: 1.054 ± 0.025	4.082GluIle: 4.082 ± 0.06	4.43GluLys: 4.43 ± 0.063	5.371GluLeu: 5.371 ± 0.082	1.411GluMet: 1.411 ± 0.031	3.072GluAsn: 3.072 ± 0.053	1.681GluPro: 1.681 ± 0.036	2.255GluGln: 2.255 ± 0.04	2.225GluArg: 2.225 ± 0.039	2.595GluSer: 2.595 ± 0.039	2.856GluThr: 2.856 ± 0.043	3.454GluVal: 3.454 ± 0.055	0.645GluTrp: 0.645 ± 0.023	1.951GluTyr: 1.951 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.467PheAla: 3.467 ± 0.049	0.492PheCys: 0.492 ± 0.016	2.924PheAsp: 2.924 ± 0.046	2.603PheGlu: 2.603 ± 0.045	2.613PhePhe: 2.613 ± 0.046	3.45PheGly: 3.45 ± 0.051	0.817PheHis: 0.817 ± 0.022	3.792PheIle: 3.792 ± 0.056	3.465PheLys: 3.465 ± 0.05	4.374PheLeu: 4.374 ± 0.061	1.15PheMet: 1.15 ± 0.028	3.278PheAsn: 3.278 ± 0.054	1.706PhePro: 1.706 ± 0.036	1.254PheGln: 1.254 ± 0.028	1.723PheArg: 1.723 ± 0.032	3.611PheSer: 3.611 ± 0.053	3.229PheThr: 3.229 ± 0.046	2.927PheVal: 2.927 ± 0.054	0.591PheTrp: 0.591 ± 0.02	2.196PheTyr: 2.196 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	4.953GlyAla: 4.953 ± 0.077	0.636GlyCys: 0.636 ± 0.023	3.574GlyAsp: 3.574 ± 0.044	3.283GlyGlu: 3.283 ± 0.052	3.753GlyPhe: 3.753 ± 0.048	5.183GlyGly: 5.183 ± 0.084	1.322GlyHis: 1.322 ± 0.037	5.435GlyIle: 5.435 ± 0.074	5.373GlyLys: 5.373 ± 0.07	6.377GlyLeu: 6.377 ± 0.068	1.68GlyMet: 1.68 ± 0.036	3.839GlyAsn: 3.839 ± 0.07	1.835GlyPro: 1.835 ± 0.046	2.199GlyGln: 2.199 ± 0.037	2.513GlyArg: 2.513 ± 0.046	4.515GlySer: 4.515 ± 0.065	4.36GlyThr: 4.36 ± 0.073	4.513GlyVal: 4.513 ± 0.066	0.989GlyTrp: 0.989 ± 0.026	3.218GlyTyr: 3.218 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.197HisAla: 1.197 ± 0.029	0.189HisCys: 0.189 ± 0.011	1.004HisAsp: 1.004 ± 0.029	0.966HisGlu: 0.966 ± 0.025	1.15HisPhe: 1.15 ± 0.027	1.22HisGly: 1.22 ± 0.032	0.54HisHis: 0.54 ± 0.02	1.427HisIle: 1.427 ± 0.031	1.097HisLys: 1.097 ± 0.028	1.962HisLeu: 1.962 ± 0.039	0.343HisMet: 0.343 ± 0.017	0.964HisAsn: 0.964 ± 0.025	1.036HisPro: 1.036 ± 0.029	0.748HisGln: 0.748 ± 0.024	0.743HisArg: 0.743 ± 0.022	1.085HisSer: 1.085 ± 0.028	1.053HisThr: 1.053 ± 0.027	1.034HisVal: 1.034 ± 0.027	0.273HisTrp: 0.273 ± 0.013	0.892HisTyr: 0.892 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.214IleAla: 6.214 ± 0.065	0.772IleCys: 0.772 ± 0.02	4.236IleAsp: 4.236 ± 0.051	4.028IleGlu: 4.028 ± 0.052	3.323IlePhe: 3.323 ± 0.054	4.858IleGly: 4.858 ± 0.058	1.279IleHis: 1.279 ± 0.026	5.563IleIle: 5.563 ± 0.069	5.356IleLys: 5.356 ± 0.057	6.202IleLeu: 6.202 ± 0.072	1.521IleMet: 1.521 ± 0.033	4.529IleAsn: 4.529 ± 0.064	3.101IlePro: 3.101 ± 0.046	2.154IleGln: 2.154 ± 0.041	2.839IleArg: 2.839 ± 0.037	5.132IleSer: 5.132 ± 0.065	4.98IleThr: 4.98 ± 0.065	4.295IleVal: 4.295 ± 0.058	0.732IleTrp: 0.732 ± 0.022	2.714IleTyr: 2.714 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	5.38LysAla: 5.38 ± 0.078	0.349LysCys: 0.349 ± 0.015	3.894LysAsp: 3.894 ± 0.059	4.162LysGlu: 4.162 ± 0.067	2.685LysPhe: 2.685 ± 0.043	4.566LysGly: 4.566 ± 0.063	1.335LysHis: 1.335 ± 0.029	5.254LysIle: 5.254 ± 0.058	5.622LysLys: 5.622 ± 0.068	6.421LysLeu: 6.421 ± 0.076	1.91LysMet: 1.91 ± 0.034	4.393LysAsn: 4.393 ± 0.056	2.981LysPro: 2.981 ± 0.05	2.967LysGln: 2.967 ± 0.042	2.719LysArg: 2.719 ± 0.043	3.969LysSer: 3.969 ± 0.054	4.345LysThr: 4.345 ± 0.057	4.432LysVal: 4.432 ± 0.05	0.827LysTrp: 0.827 ± 0.026	2.982LysTyr: 2.982 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	7.133LeuAla: 7.133 ± 0.073	0.827LeuCys: 0.827 ± 0.026	4.552LeuAsp: 4.552 ± 0.058	4.261LeuGlu: 4.261 ± 0.062	4.781LeuPhe: 4.781 ± 0.065	5.7LeuGly: 5.7 ± 0.071	1.713LeuHis: 1.713 ± 0.036	6.642LeuIle: 6.642 ± 0.077	7.566LeuLys: 7.566 ± 0.086	9.521LeuLeu: 9.521 ± 0.11	2.271LeuMet: 2.271 ± 0.042	5.76LeuAsn: 5.76 ± 0.071	4.18LeuPro: 4.18 ± 0.047	3.581LeuGln: 3.581 ± 0.057	3.432LeuArg: 3.432 ± 0.05	6.696LeuSer: 6.696 ± 0.073	5.608LeuThr: 5.608 ± 0.061	5.741LeuVal: 5.741 ± 0.066	0.928LeuTrp: 0.928 ± 0.028	3.285LeuTyr: 3.285 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.957MetAla: 1.957 ± 0.034	0.169MetCys: 0.169 ± 0.011	1.248MetAsp: 1.248 ± 0.032	1.283MetGlu: 1.283 ± 0.026	0.894MetPhe: 0.894 ± 0.025	1.565MetGly: 1.565 ± 0.036	0.484MetHis: 0.484 ± 0.02	1.619MetIle: 1.619 ± 0.032	1.894MetLys: 1.894 ± 0.035	2.231MetLeu: 2.231 ± 0.042	0.593MetMet: 0.593 ± 0.022	1.172MetAsn: 1.172 ± 0.025	1.11MetPro: 1.11 ± 0.025	0.983MetGln: 0.983 ± 0.024	0.906MetArg: 0.906 ± 0.022	1.275MetSer: 1.275 ± 0.03	1.064MetThr: 1.064 ± 0.029	1.535MetVal: 1.535 ± 0.032	0.179MetTrp: 0.179 ± 0.012	0.657MetTyr: 0.657 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.225AsnAla: 4.225 ± 0.056	0.45AsnCys: 0.45 ± 0.016	2.896AsnAsp: 2.896 ± 0.056	2.832AsnGlu: 2.832 ± 0.046	2.691AsnPhe: 2.691 ± 0.053	4.219AsnGly: 4.219 ± 0.059	1.023AsnHis: 1.023 ± 0.028	4.345AsnIle: 4.345 ± 0.057	3.956AsnLys: 3.956 ± 0.056	5.089AsnLeu: 5.089 ± 0.064	1.225AsnMet: 1.225 ± 0.023	3.591AsnAsn: 3.591 ± 0.065	2.691AsnPro: 2.691 ± 0.041	1.993AsnGln: 1.993 ± 0.04	2.208AsnArg: 2.208 ± 0.037	3.469AsnSer: 3.469 ± 0.054	3.376AsnThr: 3.376 ± 0.046	3.279AsnVal: 3.279 ± 0.054	0.77AsnTrp: 0.77 ± 0.022	2.78AsnTyr: 2.78 ± 0.052	0.0AsnXaa: 0.0 ± 0.0
Pro	3.8ProAla: 3.8 ± 0.067	0.229ProCys: 0.229 ± 0.011	2.689ProAsp: 2.689 ± 0.036	2.751ProGlu: 2.751 ± 0.038	2.024ProPhe: 2.024 ± 0.033	3.188ProGly: 3.188 ± 0.046	0.717ProHis: 0.717 ± 0.024	2.264ProIle: 2.264 ± 0.041	2.229ProLys: 2.229 ± 0.037	3.415ProLeu: 3.415 ± 0.05	0.767ProMet: 0.767 ± 0.022	1.917ProAsn: 1.917 ± 0.043	1.208ProPro: 1.208 ± 0.037	1.474ProGln: 1.474 ± 0.035	1.064ProArg: 1.064 ± 0.025	2.154ProSer: 2.154 ± 0.037	1.792ProThr: 1.792 ± 0.036	3.643ProVal: 3.643 ± 0.059	0.451ProTrp: 0.451 ± 0.017	1.568ProTyr: 1.568 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.637GlnAla: 2.637 ± 0.047	0.194GlnCys: 0.194 ± 0.01	1.49GlnAsp: 1.49 ± 0.029	1.602GlnGlu: 1.602 ± 0.035	1.645GlnPhe: 1.645 ± 0.031	1.975GlnGly: 1.975 ± 0.041	0.768GlnHis: 0.768 ± 0.02	2.496GlnIle: 2.496 ± 0.044	2.637GlnLys: 2.637 ± 0.044	3.933GlnLeu: 3.933 ± 0.054	0.887GlnMet: 0.887 ± 0.024	2.075GlnAsn: 2.075 ± 0.04	1.567GlnPro: 1.567 ± 0.037	2.116GlnGln: 2.116 ± 0.067	1.404GlnArg: 1.404 ± 0.035	2.199GlnSer: 2.199 ± 0.039	2.11GlnThr: 2.11 ± 0.041	2.398GlnVal: 2.398 ± 0.043	0.431GlnTrp: 0.431 ± 0.019	1.516GlnTyr: 1.516 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.44ArgAla: 2.44 ± 0.043	0.255ArgCys: 0.255 ± 0.016	1.972ArgAsp: 1.972 ± 0.037	2.171ArgGlu: 2.171 ± 0.05	1.952ArgPhe: 1.952 ± 0.035	2.083ArgGly: 2.083 ± 0.038	0.702ArgHis: 0.702 ± 0.021	2.913ArgIle: 2.913 ± 0.042	2.669ArgLys: 2.669 ± 0.045	3.72ArgLeu: 3.72 ± 0.049	0.996ArgMet: 0.996 ± 0.023	2.118ArgAsn: 2.118 ± 0.038	1.326ArgPro: 1.326 ± 0.029	1.479ArgGln: 1.479 ± 0.033	1.526ArgArg: 1.526 ± 0.04	2.241ArgSer: 2.241 ± 0.043	1.903ArgThr: 1.903 ± 0.036	2.368ArgVal: 2.368 ± 0.042	0.473ArgTrp: 0.473 ± 0.02	1.731ArgTyr: 1.731 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	4.923SerAla: 4.923 ± 0.059	0.54SerCys: 0.54 ± 0.019	2.972SerAsp: 2.972 ± 0.052	2.677SerGlu: 2.677 ± 0.047	3.546SerPhe: 3.546 ± 0.052	5.104SerGly: 5.104 ± 0.067	1.105SerHis: 1.105 ± 0.029	4.684SerIle: 4.684 ± 0.065	3.918SerLys: 3.918 ± 0.05	6.051SerLeu: 6.051 ± 0.064	1.25SerMet: 1.25 ± 0.027	3.237SerAsn: 3.237 ± 0.05	2.537SerPro: 2.537 ± 0.045	1.993SerGln: 1.993 ± 0.033	2.32SerArg: 2.32 ± 0.038	3.934SerSer: 3.934 ± 0.058	3.49SerThr: 3.49 ± 0.055	4.255SerVal: 4.255 ± 0.051	0.761SerTrp: 0.761 ± 0.023	2.733SerTyr: 2.733 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.026ThrAla: 5.026 ± 0.072	0.422ThrCys: 0.422 ± 0.018	3.415ThrAsp: 3.415 ± 0.05	2.789ThrGlu: 2.789 ± 0.042	2.775ThrPhe: 2.775 ± 0.047	5.265ThrGly: 5.265 ± 0.07	1.061ThrHis: 1.061 ± 0.024	4.513ThrIle: 4.513 ± 0.058	3.134ThrLys: 3.134 ± 0.043	5.352ThrLeu: 5.352 ± 0.066	1.073ThrMet: 1.073 ± 0.025	2.851ThrAsn: 2.851 ± 0.05	2.702ThrPro: 2.702 ± 0.052	1.829ThrGln: 1.829 ± 0.037	2.044ThrArg: 2.044 ± 0.037	3.518ThrSer: 3.518 ± 0.059	3.497ThrThr: 3.497 ± 0.067	4.142ThrVal: 4.142 ± 0.068	0.669ThrTrp: 0.669 ± 0.021	2.437ThrTyr: 2.437 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.827ValAla: 4.827 ± 0.072	0.616ValCys: 0.616 ± 0.022	3.361ValAsp: 3.361 ± 0.046	3.204ValGlu: 3.204 ± 0.049	3.315ValPhe: 3.315 ± 0.052	3.642ValGly: 3.642 ± 0.054	1.105ValHis: 1.105 ± 0.025	5.145ValIle: 5.145 ± 0.07	4.913ValLys: 4.913 ± 0.059	6.131ValLeu: 6.131 ± 0.075	1.485ValMet: 1.485 ± 0.033	3.906ValAsn: 3.906 ± 0.052	2.513ValPro: 2.513 ± 0.048	1.978ValGln: 1.978 ± 0.038	2.169ValArg: 2.169 ± 0.04	4.426ValSer: 4.426 ± 0.054	4.212ValThr: 4.212 ± 0.071	4.271ValVal: 4.271 ± 0.056	0.671ValTrp: 0.671 ± 0.019	2.625ValTyr: 2.625 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.808TrpAla: 0.808 ± 0.025	0.122TrpCys: 0.122 ± 0.008	0.676TrpAsp: 0.676 ± 0.022	0.564TrpGlu: 0.564 ± 0.02	0.639TrpPhe: 0.639 ± 0.022	0.84TrpGly: 0.84 ± 0.027	0.299TrpHis: 0.299 ± 0.016	0.792TrpIle: 0.792 ± 0.025	0.811TrpLys: 0.811 ± 0.026	1.192TrpLeu: 1.192 ± 0.024	0.365TrpMet: 0.365 ± 0.014	0.668TrpAsn: 0.668 ± 0.019	0.368TrpPro: 0.368 ± 0.016	0.533TrpGln: 0.533 ± 0.021	0.504TrpArg: 0.504 ± 0.017	0.61TrpSer: 0.61 ± 0.022	0.607TrpThr: 0.607 ± 0.025	0.721TrpVal: 0.721 ± 0.025	0.214TrpTrp: 0.214 ± 0.01	0.459TrpTyr: 0.459 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.797TyrAla: 2.797 ± 0.038	0.395TyrCys: 0.395 ± 0.015	2.24TyrAsp: 2.24 ± 0.043	1.901TyrGlu: 1.901 ± 0.035	2.349TyrPhe: 2.349 ± 0.039	2.79TyrGly: 2.79 ± 0.049	0.96TyrHis: 0.96 ± 0.025	2.556TyrIle: 2.556 ± 0.036	2.772TyrLys: 2.772 ± 0.047	4.114TyrLeu: 4.114 ± 0.058	0.754TyrMet: 0.754 ± 0.02	2.602TyrAsn: 2.602 ± 0.045	1.754TyrPro: 1.754 ± 0.033	1.684TyrGln: 1.684 ± 0.038	1.829TyrArg: 1.829 ± 0.034	2.66TyrSer: 2.66 ± 0.043	2.529TyrThr: 2.529 ± 0.046	2.311TyrVal: 2.311 ± 0.043	0.53TyrTrp: 0.53 ± 0.018	1.95TyrTyr: 1.95 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4924 proteins (1573549 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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