Amino acid dipepetide frequency for Wenling toga-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
23.622AlaAla: 23.622 ± 6.84
1.432AlaCys: 1.432 ± 0.605
7.874AlaAsp: 7.874 ± 3.327
5.369AlaGlu: 5.369 ± 2.269
5.011AlaPhe: 5.011 ± 1.024
7.516AlaGly: 7.516 ± 0.034
3.221AlaHis: 3.221 ± 1.781
3.937AlaIle: 3.937 ± 1.478
1.432AlaLys: 1.432 ± 0.605
10.021AlaLeu: 10.021 ± 2.049
3.221AlaMet: 3.221 ± 1.361
0.358AlaAsn: 0.358 ± 0.151
10.737AlaPro: 10.737 ± 1.396
2.505AlaGln: 2.505 ± 1.059
11.453AlaArg: 11.453 ± 1.444
6.442AlaSer: 6.442 ± 2.722
7.874AlaThr: 7.874 ± 0.186
16.106AlaVal: 16.106 ± 3.664
1.79AlaTrp: 1.79 ± 0.756
3.937AlaTyr: 3.937 ± 4.62
0.0AlaXaa: 0.0 ± 0.0
Cys
1.79CysAla: 1.79 ± 0.756
0.358CysCys: 0.358 ± 0.151
2.147CysAsp: 2.147 ± 0.907
1.074CysGlu: 1.074 ± 0.454
0.0CysPhe: 0.0 ± 0.0
2.147CysGly: 2.147 ± 2.234
0.358CysHis: 0.358 ± 0.151
0.716CysIle: 0.716 ± 0.302
0.358CysLys: 0.358 ± 0.151
1.074CysLeu: 1.074 ± 0.454
0.0CysMet: 0.0 ± 0.0
0.716CysAsn: 0.716 ± 0.302
1.074CysPro: 1.074 ± 2.688
0.358CysGln: 0.358 ± 0.151
0.716CysArg: 0.716 ± 0.302
1.074CysSer: 1.074 ± 0.454
0.358CysThr: 0.358 ± 0.151
0.716CysVal: 0.716 ± 0.302
0.358CysTrp: 0.358 ± 0.151
1.074CysTyr: 1.074 ± 0.454
0.0CysXaa: 0.0 ± 0.0
Asp
7.516AspAla: 7.516 ± 3.176
1.79AspCys: 1.79 ± 0.756
1.432AspAsp: 1.432 ± 0.605
2.863AspGlu: 2.863 ± 5.074
1.79AspPhe: 1.79 ± 2.386
2.863AspGly: 2.863 ± 1.21
1.074AspHis: 1.074 ± 0.454
2.505AspIle: 2.505 ± 2.083
1.074AspLys: 1.074 ± 0.454
3.937AspLeu: 3.937 ± 1.664
1.074AspMet: 1.074 ± 0.454
1.79AspAsn: 1.79 ± 0.756
5.369AspPro: 5.369 ± 2.269
1.432AspGln: 1.432 ± 0.605
3.937AspArg: 3.937 ± 1.664
2.505AspSer: 2.505 ± 1.059
3.579AspThr: 3.579 ± 1.629
8.948AspVal: 8.948 ± 3.781
0.716AspTrp: 0.716 ± 0.302
2.147AspTyr: 2.147 ± 2.234
0.0AspXaa: 0.0 ± 0.0
Glu
3.221GluAla: 3.221 ± 4.923
1.432GluCys: 1.432 ± 0.605
0.358GluAsp: 0.358 ± 0.151
2.147GluGlu: 2.147 ± 0.907
3.221GluPhe: 3.221 ± 1.361
1.79GluGly: 1.79 ± 0.756
0.716GluHis: 0.716 ± 0.302
2.147GluIle: 2.147 ± 2.234
1.432GluLys: 1.432 ± 0.605
5.369GluLeu: 5.369 ± 2.269
0.716GluMet: 0.716 ± 0.302
0.716GluAsn: 0.716 ± 0.302
2.505GluPro: 2.505 ± 1.059
0.358GluGln: 0.358 ± 0.151
7.158GluArg: 7.158 ± 0.117
1.074GluSer: 1.074 ± 0.454
0.358GluThr: 0.358 ± 0.151
2.863GluVal: 2.863 ± 1.21
0.358GluTrp: 0.358 ± 0.151
1.79GluTyr: 1.79 ± 2.386
0.0GluXaa: 0.0 ± 0.0
Phe
3.579PheAla: 3.579 ± 1.512
1.074PheCys: 1.074 ± 0.454
4.295PheAsp: 4.295 ± 1.815
2.147PheGlu: 2.147 ± 0.907
1.074PhePhe: 1.074 ± 0.454
3.937PheGly: 3.937 ± 1.664
1.074PheHis: 1.074 ± 0.454
1.074PheIle: 1.074 ± 0.454
0.358PheLys: 0.358 ± 2.991
2.863PheLeu: 2.863 ± 1.932
1.074PheMet: 1.074 ± 0.454
2.147PheAsn: 2.147 ± 0.907
1.79PhePro: 1.79 ± 2.386
0.716PheGln: 0.716 ± 0.302
2.147PheArg: 2.147 ± 2.234
4.653PheSer: 4.653 ± 1.966
2.147PheThr: 2.147 ± 0.907
4.295PheVal: 4.295 ± 1.327
0.358PheTrp: 0.358 ± 0.151
0.716PheTyr: 0.716 ± 0.302
0.0PheXaa: 0.0 ± 0.0
Gly
8.948GlyAla: 8.948 ± 0.639
1.432GlyCys: 1.432 ± 0.605
5.727GlyAsp: 5.727 ± 0.722
1.432GlyGlu: 1.432 ± 0.605
1.79GlyPhe: 1.79 ± 0.756
3.937GlyGly: 3.937 ± 1.478
2.147GlyHis: 2.147 ± 0.907
2.863GlyIle: 2.863 ± 5.074
0.716GlyLys: 0.716 ± 2.839
8.232GlyLeu: 8.232 ± 3.479
0.0GlyMet: 0.0 ± 0.0
0.716GlyAsn: 0.716 ± 0.302
1.432GlyPro: 1.432 ± 2.537
1.074GlyGln: 1.074 ± 0.454
4.653GlyArg: 4.653 ± 1.176
5.369GlySer: 5.369 ± 2.269
2.505GlyThr: 2.505 ± 2.083
5.369GlyVal: 5.369 ± 0.873
0.716GlyTrp: 0.716 ± 0.302
0.716GlyTyr: 0.716 ± 0.302
0.0GlyXaa: 0.0 ± 0.0
His
4.295HisAla: 4.295 ± 1.815
1.432HisCys: 1.432 ± 0.605
0.358HisAsp: 0.358 ± 0.151
2.147HisGlu: 2.147 ± 0.907
0.358HisPhe: 0.358 ± 0.151
0.716HisGly: 0.716 ± 0.302
0.0HisHis: 0.0 ± 0.0
1.074HisIle: 1.074 ± 2.688
0.716HisLys: 0.716 ± 0.302
0.716HisLeu: 0.716 ± 0.302
1.074HisMet: 1.074 ± 0.454
0.358HisAsn: 0.358 ± 0.151
1.074HisPro: 1.074 ± 0.454
0.358HisGln: 0.358 ± 0.151
2.147HisArg: 2.147 ± 0.907
1.074HisSer: 1.074 ± 5.83
2.505HisThr: 2.505 ± 1.059
3.221HisVal: 3.221 ± 1.361
0.358HisTrp: 0.358 ± 0.151
1.074HisTyr: 1.074 ± 0.454
0.0HisXaa: 0.0 ± 0.0
Ile
3.221IleAla: 3.221 ± 1.781
0.358IleCys: 0.358 ± 0.151
2.505IleAsp: 2.505 ± 2.083
1.432IleGlu: 1.432 ± 0.605
0.716IlePhe: 0.716 ± 0.302
2.863IleGly: 2.863 ± 5.074
0.358IleHis: 0.358 ± 0.151
1.432IleIle: 1.432 ± 0.605
1.074IleLys: 1.074 ± 0.454
2.505IleLeu: 2.505 ± 1.059
0.0IleMet: 0.0 ± 1.493
0.358IleAsn: 0.358 ± 0.151
2.505IlePro: 2.505 ± 5.225
0.358IleGln: 0.358 ± 0.151
2.505IleArg: 2.505 ± 1.059
4.295IleSer: 4.295 ± 1.815
2.505IleThr: 2.505 ± 2.083
6.084IleVal: 6.084 ± 3.713
0.0IleTrp: 0.0 ± 0.0
1.432IleTyr: 1.432 ± 5.679
0.0IleXaa: 0.0 ± 0.0
Lys
1.074LysAla: 1.074 ± 0.454
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
0.358LysGlu: 0.358 ± 0.151
1.074LysPhe: 1.074 ± 0.454
0.716LysGly: 0.716 ± 0.302
0.716LysHis: 0.716 ± 0.302
0.716LysIle: 0.716 ± 0.302
0.0LysLys: 0.0 ± 0.0
1.79LysLeu: 1.79 ± 0.756
0.358LysMet: 0.358 ± 0.151
0.358LysAsn: 0.358 ± 0.151
0.716LysPro: 0.716 ± 0.302
0.358LysGln: 0.358 ± 0.151
0.716LysArg: 0.716 ± 2.839
1.074LysSer: 1.074 ± 2.688
1.432LysThr: 1.432 ± 0.605
1.79LysVal: 1.79 ± 2.386
0.0LysTrp: 0.0 ± 0.0
0.358LysTyr: 0.358 ± 0.151
0.0LysXaa: 0.0 ± 0.0
Leu
8.59LeuAla: 8.59 ± 2.654
1.074LeuCys: 1.074 ± 2.688
4.653LeuAsp: 4.653 ± 1.966
2.863LeuGlu: 2.863 ± 1.21
5.727LeuPhe: 5.727 ± 2.42
6.442LeuGly: 6.442 ± 0.419
3.221LeuHis: 3.221 ± 1.361
1.432LeuIle: 1.432 ± 0.605
0.358LeuLys: 0.358 ± 0.151
7.158LeuLeu: 7.158 ± 0.117
1.074LeuMet: 1.074 ± 0.454
1.432LeuAsn: 1.432 ± 0.605
6.442LeuPro: 6.442 ± 3.561
2.505LeuGln: 2.505 ± 1.059
11.095LeuArg: 11.095 ± 1.595
8.59LeuSer: 8.59 ± 3.63
4.295LeuThr: 4.295 ± 1.815
7.158LeuVal: 7.158 ± 0.117
0.358LeuTrp: 0.358 ± 0.151
2.147LeuTyr: 2.147 ± 0.907
0.0LeuXaa: 0.0 ± 0.0
Met
1.79MetAla: 1.79 ± 0.756
0.358MetCys: 0.358 ± 0.151
1.79MetAsp: 1.79 ± 0.756
0.0MetGlu: 0.0 ± 0.0
1.074MetPhe: 1.074 ± 2.688
0.716MetGly: 0.716 ± 0.302
0.716MetHis: 0.716 ± 0.302
0.358MetIle: 0.358 ± 0.151
0.0MetLys: 0.0 ± 0.0
1.432MetLeu: 1.432 ± 0.605
0.358MetMet: 0.358 ± 0.151
0.358MetAsn: 0.358 ± 0.151
1.432MetPro: 1.432 ± 0.605
0.0MetGln: 0.0 ± 0.0
1.074MetArg: 1.074 ± 0.454
1.79MetSer: 1.79 ± 0.756
1.074MetThr: 1.074 ± 0.454
1.074MetVal: 1.074 ± 0.454
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.221AsnAla: 3.221 ± 1.361
0.0AsnCys: 0.0 ± 0.0
2.147AsnAsp: 2.147 ± 2.234
0.716AsnGlu: 0.716 ± 0.302
0.358AsnPhe: 0.358 ± 0.151
1.074AsnGly: 1.074 ± 0.454
0.0AsnHis: 0.0 ± 0.0
0.716AsnIle: 0.716 ± 2.839
0.0AsnLys: 0.0 ± 0.0
1.432AsnLeu: 1.432 ± 0.605
0.0AsnMet: 0.0 ± 0.0
0.358AsnAsn: 0.358 ± 0.151
0.716AsnPro: 0.716 ± 0.302
1.074AsnGln: 1.074 ± 0.454
1.79AsnArg: 1.79 ± 0.756
0.716AsnSer: 0.716 ± 0.302
1.79AsnThr: 1.79 ± 0.756
2.147AsnVal: 2.147 ± 0.907
0.358AsnTrp: 0.358 ± 0.151
0.716AsnTyr: 0.716 ± 0.302
0.0AsnXaa: 0.0 ± 0.0
Pro
13.601ProAla: 13.601 ± 5.747
0.358ProCys: 0.358 ± 0.151
4.653ProAsp: 4.653 ± 1.176
2.147ProGlu: 2.147 ± 8.518
2.863ProPhe: 2.863 ± 1.21
2.863ProGly: 2.863 ± 1.932
2.147ProHis: 2.147 ± 2.234
2.147ProIle: 2.147 ± 0.907
1.432ProLys: 1.432 ± 2.537
7.158ProLeu: 7.158 ± 0.117
0.716ProMet: 0.716 ± 0.302
1.074ProAsn: 1.074 ± 0.454
5.727ProPro: 5.727 ± 3.864
2.147ProGln: 2.147 ± 0.907
3.937ProArg: 3.937 ± 4.62
4.295ProSer: 4.295 ± 4.469
3.937ProThr: 3.937 ± 1.478
6.084ProVal: 6.084 ± 2.571
1.432ProTrp: 1.432 ± 0.605
1.074ProTyr: 1.074 ± 0.454
0.0ProXaa: 0.0 ± 0.0
Gln
1.074GlnAla: 1.074 ± 0.454
0.0GlnCys: 0.0 ± 0.0
0.358GlnAsp: 0.358 ± 0.151
0.716GlnGlu: 0.716 ± 0.302
1.074GlnPhe: 1.074 ± 0.454
0.716GlnGly: 0.716 ± 2.839
0.0GlnHis: 0.0 ± 0.0
0.716GlnIle: 0.716 ± 0.302
0.0GlnLys: 0.0 ± 0.0
2.505GlnLeu: 2.505 ± 1.059
0.358GlnMet: 0.358 ± 0.151
1.074GlnAsn: 1.074 ± 0.454
1.432GlnPro: 1.432 ± 0.605
1.432GlnGln: 1.432 ± 0.605
2.147GlnArg: 2.147 ± 0.907
0.716GlnSer: 0.716 ± 0.302
1.432GlnThr: 1.432 ± 0.605
2.147GlnVal: 2.147 ± 0.907
0.0GlnTrp: 0.0 ± 0.0
1.79GlnTyr: 1.79 ± 0.756
0.0GlnXaa: 0.0 ± 0.0
Arg
11.811ArgAla: 11.811 ± 4.435
2.147ArgCys: 2.147 ± 2.234
5.369ArgAsp: 5.369 ± 2.269
2.147ArgGlu: 2.147 ± 0.907
4.295ArgPhe: 4.295 ± 1.815
3.937ArgGly: 3.937 ± 1.664
1.79ArgHis: 1.79 ± 0.756
2.863ArgIle: 2.863 ± 1.932
1.432ArgLys: 1.432 ± 0.605
8.948ArgLeu: 8.948 ± 0.639
1.432ArgMet: 1.432 ± 0.536
1.074ArgAsn: 1.074 ± 0.454
7.874ArgPro: 7.874 ± 0.186
0.716ArgGln: 0.716 ± 0.302
8.948ArgArg: 8.948 ± 3.781
6.8ArgSer: 6.8 ± 0.268
5.369ArgThr: 5.369 ± 2.269
10.737ArgVal: 10.737 ± 1.746
0.358ArgTrp: 0.358 ± 0.151
2.147ArgTyr: 2.147 ± 0.907
0.0ArgXaa: 0.0 ± 0.0
Ser
8.948SerAla: 8.948 ± 3.781
0.716SerCys: 0.716 ± 0.302
5.369SerAsp: 5.369 ± 2.269
3.221SerGlu: 3.221 ± 1.361
3.579SerPhe: 3.579 ± 1.512
4.653SerGly: 4.653 ± 1.176
1.79SerHis: 1.79 ± 0.756
3.221SerIle: 3.221 ± 1.781
0.358SerLys: 0.358 ± 0.151
6.8SerLeu: 6.8 ± 0.268
0.716SerMet: 0.716 ± 0.302
1.432SerAsn: 1.432 ± 2.537
4.653SerPro: 4.653 ± 1.966
0.358SerGln: 0.358 ± 0.151
7.158SerArg: 7.158 ± 3.025
5.011SerSer: 5.011 ± 2.117
3.221SerThr: 3.221 ± 1.781
6.442SerVal: 6.442 ± 0.419
0.358SerTrp: 0.358 ± 2.991
1.074SerTyr: 1.074 ± 0.454
0.0SerXaa: 0.0 ± 0.0
Thr
9.664ThrAla: 9.664 ± 0.942
0.0ThrCys: 0.0 ± 0.0
3.579ThrAsp: 3.579 ± 1.629
1.432ThrGlu: 1.432 ± 0.605
1.79ThrPhe: 1.79 ± 5.528
4.653ThrGly: 4.653 ± 1.966
1.79ThrHis: 1.79 ± 0.756
2.147ThrIle: 2.147 ± 0.907
1.79ThrLys: 1.79 ± 0.756
3.937ThrLeu: 3.937 ± 1.478
0.716ThrMet: 0.716 ± 0.302
2.147ThrAsn: 2.147 ± 2.234
2.147ThrPro: 2.147 ± 2.234
1.79ThrGln: 1.79 ± 0.756
5.011ThrArg: 5.011 ± 2.117
4.295ThrSer: 4.295 ± 1.327
3.937ThrThr: 3.937 ± 1.664
6.8ThrVal: 6.8 ± 2.874
1.074ThrTrp: 1.074 ± 0.454
1.432ThrTyr: 1.432 ± 0.605
0.0ThrXaa: 0.0 ± 0.0
Val
15.39ValAla: 15.39 ± 0.22
2.147ValCys: 2.147 ± 0.907
4.295ValAsp: 4.295 ± 1.815
5.369ValGlu: 5.369 ± 2.269
3.579ValPhe: 3.579 ± 1.512
6.084ValGly: 6.084 ± 2.571
3.579ValHis: 3.579 ± 1.629
6.442ValIle: 6.442 ± 6.703
0.716ValLys: 0.716 ± 0.302
6.084ValLeu: 6.084 ± 0.571
1.79ValMet: 1.79 ± 0.756
1.79ValAsn: 1.79 ± 0.756
9.664ValPro: 9.664 ± 2.2
0.716ValGln: 0.716 ± 0.302
8.948ValArg: 8.948 ± 3.781
7.874ValSer: 7.874 ± 3.327
8.59ValThr: 8.59 ± 0.488
11.095ValVal: 11.095 ± 4.737
0.358ValTrp: 0.358 ± 0.151
3.221ValTyr: 3.221 ± 1.361
0.0ValXaa: 0.0 ± 0.0
Trp
0.358TrpAla: 0.358 ± 0.151
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.358TrpGlu: 0.358 ± 0.151
0.716TrpPhe: 0.716 ± 0.302
0.358TrpGly: 0.358 ± 2.991
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.79TrpLeu: 1.79 ± 0.756
0.0TrpMet: 0.0 ± 0.0
0.358TrpAsn: 0.358 ± 0.151
1.432TrpPro: 1.432 ± 0.605
1.074TrpGln: 1.074 ± 2.688
0.358TrpArg: 0.358 ± 0.151
0.358TrpSer: 0.358 ± 0.151
0.358TrpThr: 0.358 ± 0.151
1.074TrpVal: 1.074 ± 0.454
0.0TrpTrp: 0.0 ± 0.0
0.716TrpTyr: 0.716 ± 0.302
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.147TyrAla: 2.147 ± 2.234
0.358TyrCys: 0.358 ± 0.151
1.432TyrAsp: 1.432 ± 2.537
1.79TyrGlu: 1.79 ± 0.756
1.432TyrPhe: 1.432 ± 0.605
1.79TyrGly: 1.79 ± 0.756
0.358TyrHis: 0.358 ± 0.151
0.358TyrIle: 0.358 ± 0.151
0.358TyrLys: 0.358 ± 0.151
2.863TyrLeu: 2.863 ± 1.932
0.358TyrMet: 0.358 ± 0.151
0.716TyrAsn: 0.716 ± 0.302
1.074TyrPro: 1.074 ± 2.688
0.358TyrGln: 0.358 ± 0.151
4.295TyrArg: 4.295 ± 1.815
1.074TyrSer: 1.074 ± 0.454
2.863TyrThr: 2.863 ± 1.932
3.579TyrVal: 3.579 ± 1.512
0.358TyrTrp: 0.358 ± 2.991
0.358TyrTyr: 0.358 ± 0.151
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2795 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski