Amino acid dipepetide frequency for Beihai sobemo-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.302AlaAla: 13.302 ± 2.306
0.782AlaCys: 0.782 ± 1.095
8.607AlaAsp: 8.607 ± 1.404
3.13AlaGlu: 3.13 ± 2.887
3.912AlaPhe: 3.912 ± 0.993
7.825AlaGly: 7.825 ± 0.49
2.347AlaHis: 2.347 ± 1.198
5.477AlaIle: 5.477 ± 0.194
7.042AlaLys: 7.042 ± 2.1
11.737AlaLeu: 11.737 ± 2.978
1.565AlaMet: 1.565 ± 0.799
3.13AlaAsn: 3.13 ± 1.392
3.912AlaPro: 3.912 ± 2.487
3.13AlaGln: 3.13 ± 1.598
7.042AlaArg: 7.042 ± 0.89
5.477AlaSer: 5.477 ± 1.301
3.912AlaThr: 3.912 ± 0.502
14.085AlaVal: 14.085 ± 1.779
0.782AlaTrp: 0.782 ± 0.399
2.347AlaTyr: 2.347 ± 1.791
0.0AlaXaa: 0.0 ± 0.0
Cys
0.782CysAla: 0.782 ± 0.399
0.782CysCys: 0.782 ± 1.095
1.565CysAsp: 1.565 ± 0.799
2.347CysGlu: 2.347 ± 0.297
0.0CysPhe: 0.0 ± 0.0
2.347CysGly: 2.347 ± 1.198
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.782CysLys: 0.782 ± 1.095
0.782CysLeu: 0.782 ± 0.399
0.782CysMet: 0.782 ± 0.399
1.565CysAsn: 1.565 ± 0.799
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.565CysArg: 1.565 ± 0.696
1.565CysSer: 1.565 ± 0.696
1.565CysThr: 1.565 ± 0.799
0.0CysVal: 0.0 ± 0.0
0.782CysTrp: 0.782 ± 1.095
0.782CysTyr: 0.782 ± 0.399
0.0CysXaa: 0.0 ± 0.0
Asp
9.39AspAla: 9.39 ± 2.681
0.0AspCys: 0.0 ± 0.0
4.695AspAsp: 4.695 ± 2.397
6.26AspGlu: 6.26 ± 3.196
7.042AspPhe: 7.042 ± 3.595
1.565AspGly: 1.565 ± 0.799
1.565AspHis: 1.565 ± 0.696
3.13AspIle: 3.13 ± 0.103
0.782AspLys: 0.782 ± 0.399
5.477AspLeu: 5.477 ± 0.194
0.782AspMet: 0.782 ± 0.399
3.912AspAsn: 3.912 ± 0.993
4.695AspPro: 4.695 ± 0.902
0.782AspGln: 0.782 ± 0.399
3.912AspArg: 3.912 ± 1.997
4.695AspSer: 4.695 ± 2.397
3.912AspThr: 3.912 ± 0.993
7.042AspVal: 7.042 ± 2.1
0.782AspTrp: 0.782 ± 0.399
0.782AspTyr: 0.782 ± 0.399
0.0AspXaa: 0.0 ± 0.0
Glu
3.912GluAla: 3.912 ± 0.502
0.782GluCys: 0.782 ± 0.399
3.13GluAsp: 3.13 ± 1.598
2.347GluGlu: 2.347 ± 1.198
1.565GluPhe: 1.565 ± 0.799
7.042GluGly: 7.042 ± 0.605
0.782GluHis: 0.782 ± 1.095
0.782GluIle: 0.782 ± 0.399
1.565GluLys: 1.565 ± 0.799
3.13GluLeu: 3.13 ± 0.103
0.0GluMet: 0.0 ± 0.0
3.13GluAsn: 3.13 ± 1.598
3.912GluPro: 3.912 ± 0.502
0.782GluGln: 0.782 ± 0.399
3.13GluArg: 3.13 ± 1.598
3.13GluSer: 3.13 ± 1.598
0.782GluThr: 0.782 ± 0.399
1.565GluVal: 1.565 ± 0.696
2.347GluTrp: 2.347 ± 0.297
1.565GluTyr: 1.565 ± 0.799
0.0GluXaa: 0.0 ± 0.0
Phe
5.477PheAla: 5.477 ± 1.301
0.0PheCys: 0.0 ± 0.0
4.695PheAsp: 4.695 ± 0.902
1.565PheGlu: 1.565 ± 0.799
0.782PhePhe: 0.782 ± 0.399
5.477PheGly: 5.477 ± 1.688
2.347PheHis: 2.347 ± 1.198
0.782PheIle: 0.782 ± 1.095
0.782PheLys: 0.782 ± 0.399
0.782PheLeu: 0.782 ± 0.399
0.0PheMet: 0.0 ± 0.0
0.782PheAsn: 0.782 ± 1.095
0.782PhePro: 0.782 ± 0.399
0.0PheGln: 0.0 ± 0.0
3.13PheArg: 3.13 ± 1.598
3.912PheSer: 3.912 ± 0.502
3.13PheThr: 3.13 ± 0.103
5.477PheVal: 5.477 ± 2.796
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.477GlyAla: 5.477 ± 1.688
1.565GlyCys: 1.565 ± 0.799
6.26GlyAsp: 6.26 ± 0.206
5.477GlyGlu: 5.477 ± 2.796
3.912GlyPhe: 3.912 ± 0.502
7.042GlyGly: 7.042 ± 2.384
2.347GlyHis: 2.347 ± 1.198
2.347GlyIle: 2.347 ± 0.297
3.912GlyLys: 3.912 ± 0.502
4.695GlyLeu: 4.695 ± 0.902
1.565GlyMet: 1.565 ± 0.696
3.912GlyAsn: 3.912 ± 0.993
2.347GlyPro: 2.347 ± 0.297
3.912GlyGln: 3.912 ± 0.993
4.695GlyArg: 4.695 ± 2.088
7.042GlySer: 7.042 ± 3.879
2.347GlyThr: 2.347 ± 0.297
9.39GlyVal: 9.39 ± 1.804
0.782GlyTrp: 0.782 ± 0.399
0.782GlyTyr: 0.782 ± 0.399
0.0GlyXaa: 0.0 ± 0.0
His
3.912HisAla: 3.912 ± 1.997
0.782HisCys: 0.782 ± 0.399
1.565HisAsp: 1.565 ± 0.799
1.565HisGlu: 1.565 ± 0.696
0.0HisPhe: 0.0 ± 0.0
0.782HisGly: 0.782 ± 0.399
2.347HisHis: 2.347 ± 0.297
0.782HisIle: 0.782 ± 0.399
1.565HisLys: 1.565 ± 0.696
5.477HisLeu: 5.477 ± 1.688
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.347HisGln: 2.347 ± 1.791
1.565HisArg: 1.565 ± 0.696
2.347HisSer: 2.347 ± 1.198
0.0HisThr: 0.0 ± 0.0
3.13HisVal: 3.13 ± 0.103
0.0HisTrp: 0.0 ± 0.0
0.782HisTyr: 0.782 ± 0.399
0.0HisXaa: 0.0 ± 0.0
Ile
1.565IleAla: 1.565 ± 0.799
0.0IleCys: 0.0 ± 0.0
3.912IleAsp: 3.912 ± 0.502
0.0IleGlu: 0.0 ± 0.0
1.565IlePhe: 1.565 ± 0.696
3.13IleGly: 3.13 ± 0.103
1.565IleHis: 1.565 ± 0.799
2.347IleIle: 2.347 ± 0.297
3.13IleLys: 3.13 ± 1.392
1.565IleLeu: 1.565 ± 0.696
2.347IleMet: 2.347 ± 0.564
0.782IleAsn: 0.782 ± 0.399
0.782IlePro: 0.782 ± 0.399
1.565IleGln: 1.565 ± 0.799
0.782IleArg: 0.782 ± 1.095
3.912IleSer: 3.912 ± 0.502
0.782IleThr: 0.782 ± 1.095
0.782IleVal: 0.782 ± 1.095
1.565IleTrp: 1.565 ± 0.696
1.565IleTyr: 1.565 ± 0.696
0.0IleXaa: 0.0 ± 0.0
Lys
6.26LysAla: 6.26 ± 3.196
0.0LysCys: 0.0 ± 0.0
4.695LysAsp: 4.695 ± 0.902
2.347LysGlu: 2.347 ± 0.297
3.912LysPhe: 3.912 ± 0.502
2.347LysGly: 2.347 ± 0.297
3.13LysHis: 3.13 ± 1.598
0.782LysIle: 0.782 ± 0.399
4.695LysLys: 4.695 ± 2.397
3.912LysLeu: 3.912 ± 0.502
0.0LysMet: 0.0 ± 0.0
0.782LysAsn: 0.782 ± 1.095
1.565LysPro: 1.565 ± 0.696
3.912LysGln: 3.912 ± 0.502
1.565LysArg: 1.565 ± 0.799
3.912LysSer: 3.912 ± 1.997
0.0LysThr: 0.0 ± 0.0
2.347LysVal: 2.347 ± 0.297
0.0LysTrp: 0.0 ± 0.0
2.347LysTyr: 2.347 ± 1.198
0.0LysXaa: 0.0 ± 0.0
Leu
10.955LeuAla: 10.955 ± 1.882
1.565LeuCys: 1.565 ± 0.799
3.13LeuAsp: 3.13 ± 1.598
1.565LeuGlu: 1.565 ± 0.799
2.347LeuPhe: 2.347 ± 0.297
2.347LeuGly: 2.347 ± 0.297
2.347LeuHis: 2.347 ± 0.297
2.347LeuIle: 2.347 ± 1.198
2.347LeuLys: 2.347 ± 1.198
7.825LeuLeu: 7.825 ± 3.995
0.782LeuMet: 0.782 ± 0.399
4.695LeuAsn: 4.695 ± 0.593
5.477LeuPro: 5.477 ± 0.194
2.347LeuGln: 2.347 ± 3.286
3.912LeuArg: 3.912 ± 2.487
8.607LeuSer: 8.607 ± 0.091
3.912LeuThr: 3.912 ± 0.993
4.695LeuVal: 4.695 ± 0.593
2.347LeuTrp: 2.347 ± 1.198
0.782LeuTyr: 0.782 ± 0.399
0.0LeuXaa: 0.0 ± 0.0
Met
0.782MetAla: 0.782 ± 1.095
0.782MetCys: 0.782 ± 1.095
2.347MetAsp: 2.347 ± 0.297
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.565MetGly: 1.565 ± 0.799
0.782MetHis: 0.782 ± 1.095
1.565MetIle: 1.565 ± 0.799
0.782MetLys: 0.782 ± 0.399
1.565MetLeu: 1.565 ± 0.799
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.782MetPro: 0.782 ± 0.399
0.0MetGln: 0.0 ± 0.0
2.347MetArg: 2.347 ± 1.198
3.13MetSer: 3.13 ± 1.392
0.782MetThr: 0.782 ± 0.399
1.565MetVal: 1.565 ± 0.696
0.782MetTrp: 0.782 ± 0.399
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.912AsnAla: 3.912 ± 2.487
0.782AsnCys: 0.782 ± 0.399
2.347AsnAsp: 2.347 ± 1.198
0.782AsnGlu: 0.782 ± 0.399
0.0AsnPhe: 0.0 ± 0.0
3.912AsnGly: 3.912 ± 0.993
0.782AsnHis: 0.782 ± 0.399
1.565AsnIle: 1.565 ± 0.799
4.695AsnLys: 4.695 ± 0.593
2.347AsnLeu: 2.347 ± 1.791
0.782AsnMet: 0.782 ± 1.095
0.782AsnAsn: 0.782 ± 1.095
3.912AsnPro: 3.912 ± 5.477
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
3.912AsnSer: 3.912 ± 0.993
2.347AsnThr: 2.347 ± 1.198
2.347AsnVal: 2.347 ± 0.297
0.782AsnTrp: 0.782 ± 0.399
1.565AsnTyr: 1.565 ± 0.696
0.0AsnXaa: 0.0 ± 0.0
Pro
5.477ProAla: 5.477 ± 0.194
0.0ProCys: 0.0 ± 0.0
3.912ProAsp: 3.912 ± 0.502
3.912ProGlu: 3.912 ± 1.997
3.13ProPhe: 3.13 ± 0.103
0.782ProGly: 0.782 ± 0.399
1.565ProHis: 1.565 ± 0.696
2.347ProIle: 2.347 ± 3.286
2.347ProLys: 2.347 ± 1.198
3.912ProLeu: 3.912 ± 0.502
0.0ProMet: 0.0 ± 0.0
1.565ProAsn: 1.565 ± 0.696
2.347ProPro: 2.347 ± 1.198
2.347ProGln: 2.347 ± 1.198
2.347ProArg: 2.347 ± 3.286
3.912ProSer: 3.912 ± 2.487
1.565ProThr: 1.565 ± 0.799
1.565ProVal: 1.565 ± 0.799
0.0ProTrp: 0.0 ± 0.0
0.782ProTyr: 0.782 ± 1.095
0.0ProXaa: 0.0 ± 0.0
Gln
4.695GlnAla: 4.695 ± 0.902
0.782GlnCys: 0.782 ± 0.399
1.565GlnAsp: 1.565 ± 0.696
1.565GlnGlu: 1.565 ± 0.799
0.0GlnPhe: 0.0 ± 0.0
4.695GlnGly: 4.695 ± 0.902
0.0GlnHis: 0.0 ± 0.0
0.782GlnIle: 0.782 ± 1.095
0.782GlnLys: 0.782 ± 0.399
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
0.782GlnAsn: 0.782 ± 0.399
3.912GlnPro: 3.912 ± 1.997
2.347GlnGln: 2.347 ± 0.297
1.565GlnArg: 1.565 ± 2.191
2.347GlnSer: 2.347 ± 0.297
1.565GlnThr: 1.565 ± 0.696
2.347GlnVal: 2.347 ± 0.297
1.565GlnTrp: 1.565 ± 0.696
0.782GlnTyr: 0.782 ± 0.399
0.0GlnXaa: 0.0 ± 0.0
Arg
7.042ArgAla: 7.042 ± 2.384
2.347ArgCys: 2.347 ± 0.297
2.347ArgAsp: 2.347 ± 1.198
0.0ArgGlu: 0.0 ± 0.0
3.912ArgPhe: 3.912 ± 0.502
6.26ArgGly: 6.26 ± 4.279
0.782ArgHis: 0.782 ± 0.399
0.782ArgIle: 0.782 ± 0.399
3.13ArgLys: 3.13 ± 0.103
3.912ArgLeu: 3.912 ± 0.502
2.347ArgMet: 2.347 ± 1.791
1.565ArgAsn: 1.565 ± 0.696
2.347ArgPro: 2.347 ± 0.297
1.565ArgGln: 1.565 ± 0.799
9.39ArgArg: 9.39 ± 4.176
3.912ArgSer: 3.912 ± 0.502
0.782ArgThr: 0.782 ± 1.095
5.477ArgVal: 5.477 ± 1.301
0.782ArgTrp: 0.782 ± 0.399
1.565ArgTyr: 1.565 ± 0.799
0.0ArgXaa: 0.0 ± 0.0
Ser
10.172SerAla: 10.172 ± 0.787
1.565SerCys: 1.565 ± 0.696
3.13SerAsp: 3.13 ± 1.392
3.912SerGlu: 3.912 ± 0.502
3.13SerPhe: 3.13 ± 0.103
8.607SerGly: 8.607 ± 1.404
3.13SerHis: 3.13 ± 0.103
3.13SerIle: 3.13 ± 0.103
3.13SerLys: 3.13 ± 1.598
7.042SerLeu: 7.042 ± 2.1
3.13SerMet: 3.13 ± 0.103
3.13SerAsn: 3.13 ± 2.887
1.565SerPro: 1.565 ± 0.799
1.565SerGln: 1.565 ± 0.799
3.912SerArg: 3.912 ± 0.502
12.52SerSer: 12.52 ± 4.073
5.477SerThr: 5.477 ± 1.688
7.825SerVal: 7.825 ± 1.005
2.347SerTrp: 2.347 ± 3.286
3.912SerTyr: 3.912 ± 0.502
0.0SerXaa: 0.0 ± 0.0
Thr
3.13ThrAla: 3.13 ± 0.103
2.347ThrCys: 2.347 ± 1.198
3.912ThrAsp: 3.912 ± 0.993
0.0ThrGlu: 0.0 ± 0.0
0.782ThrPhe: 0.782 ± 0.399
3.13ThrGly: 3.13 ± 1.392
0.782ThrHis: 0.782 ± 1.095
1.565ThrIle: 1.565 ± 2.191
0.782ThrLys: 0.782 ± 0.399
4.695ThrLeu: 4.695 ± 2.088
0.782ThrMet: 0.782 ± 0.399
0.782ThrAsn: 0.782 ± 1.095
3.13ThrPro: 3.13 ± 0.103
0.782ThrGln: 0.782 ± 0.399
0.782ThrArg: 0.782 ± 0.399
6.26ThrSer: 6.26 ± 1.289
5.477ThrThr: 5.477 ± 1.688
3.13ThrVal: 3.13 ± 0.103
0.782ThrTrp: 0.782 ± 0.399
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.39ValAla: 9.39 ± 2.681
3.13ValCys: 3.13 ± 0.103
5.477ValAsp: 5.477 ± 1.301
4.695ValGlu: 4.695 ± 0.902
3.13ValPhe: 3.13 ± 1.598
7.825ValGly: 7.825 ± 1.005
1.565ValHis: 1.565 ± 2.191
1.565ValIle: 1.565 ± 0.799
3.912ValLys: 3.912 ± 1.997
4.695ValLeu: 4.695 ± 0.902
2.347ValMet: 2.347 ± 1.198
2.347ValAsn: 2.347 ± 1.198
2.347ValPro: 2.347 ± 0.297
3.13ValGln: 3.13 ± 0.103
3.912ValArg: 3.912 ± 0.502
8.607ValSer: 8.607 ± 2.899
3.13ValThr: 3.13 ± 2.887
4.695ValVal: 4.695 ± 0.902
1.565ValTrp: 1.565 ± 0.696
2.347ValTyr: 2.347 ± 0.297
0.0ValXaa: 0.0 ± 0.0
Trp
3.13TrpAla: 3.13 ± 0.103
0.0TrpCys: 0.0 ± 0.0
0.782TrpAsp: 0.782 ± 0.399
1.565TrpGlu: 1.565 ± 0.799
0.782TrpPhe: 0.782 ± 0.399
0.782TrpGly: 0.782 ± 1.095
0.0TrpHis: 0.0 ± 0.0
0.782TrpIle: 0.782 ± 0.399
0.782TrpLys: 0.782 ± 0.399
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.627
2.347TrpAsn: 2.347 ± 1.791
0.0TrpPro: 0.0 ± 0.0
0.782TrpGln: 0.782 ± 1.095
2.347TrpArg: 2.347 ± 0.297
1.565TrpSer: 1.565 ± 0.696
0.0TrpThr: 0.0 ± 0.0
0.782TrpVal: 0.782 ± 0.399
0.0TrpTrp: 0.0 ± 0.0
0.782TrpTyr: 0.782 ± 0.399
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.782TyrAla: 0.782 ± 1.095
0.0TyrCys: 0.0 ± 0.0
3.13TyrAsp: 3.13 ± 1.598
2.347TyrGlu: 2.347 ± 1.198
0.0TyrPhe: 0.0 ± 0.0
2.347TyrGly: 2.347 ± 1.198
0.782TyrHis: 0.782 ± 0.399
0.782TyrIle: 0.782 ± 1.095
1.565TyrLys: 1.565 ± 0.799
0.782TyrLeu: 0.782 ± 1.095
1.565TyrMet: 1.565 ± 0.799
1.565TyrAsn: 1.565 ± 0.696
0.0TyrPro: 0.0 ± 0.0
0.782TyrGln: 0.782 ± 0.399
2.347TyrArg: 2.347 ± 1.198
1.565TyrSer: 1.565 ± 2.191
1.565TyrThr: 1.565 ± 0.696
1.565TyrVal: 1.565 ± 0.799
0.0TyrTrp: 0.0 ± 0.0
1.565TyrTyr: 1.565 ± 0.696
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1279 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski