Amino acid dipepetide frequency for Psychrosphaera saromensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.45AlaAla: 6.45 ± 0.109	0.801AlaCys: 0.801 ± 0.031	4.601AlaAsp: 4.601 ± 0.082	5.312AlaGlu: 5.312 ± 0.087	3.176AlaPhe: 3.176 ± 0.058	5.217AlaGly: 5.217 ± 0.082	1.378AlaHis: 1.378 ± 0.045	5.784AlaIle: 5.784 ± 0.082	5.315AlaLys: 5.315 ± 0.081	8.205AlaLeu: 8.205 ± 0.098	2.089AlaMet: 2.089 ± 0.051	3.81AlaAsn: 3.81 ± 0.061	2.38AlaPro: 2.38 ± 0.06	3.315AlaGln: 3.315 ± 0.059	2.799AlaArg: 2.799 ± 0.057	5.097AlaSer: 5.097 ± 0.07	4.273AlaThr: 4.273 ± 0.075	5.315AlaVal: 5.315 ± 0.091	0.768AlaTrp: 0.768 ± 0.026	2.263AlaTyr: 2.263 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.611CysAla: 0.611 ± 0.029	0.12CysCys: 0.12 ± 0.012	0.544CysAsp: 0.544 ± 0.023	0.525CysGlu: 0.525 ± 0.023	0.434CysPhe: 0.434 ± 0.021	0.71CysGly: 0.71 ± 0.027	0.257CysHis: 0.257 ± 0.014	0.611CysIle: 0.611 ± 0.027	0.493CysLys: 0.493 ± 0.025	0.833CysLeu: 0.833 ± 0.027	0.182CysMet: 0.182 ± 0.014	0.369CysAsn: 0.369 ± 0.017	0.389CysPro: 0.389 ± 0.02	0.393CysGln: 0.393 ± 0.023	0.356CysArg: 0.356 ± 0.017	0.685CysSer: 0.685 ± 0.028	0.454CysThr: 0.454 ± 0.023	0.556CysVal: 0.556 ± 0.024	0.13CysTrp: 0.13 ± 0.022	0.272CysTyr: 0.272 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.474AspAla: 4.474 ± 0.079	0.457AspCys: 0.457 ± 0.023	3.544AspAsp: 3.544 ± 0.079	3.936AspGlu: 3.936 ± 0.077	2.78AspPhe: 2.78 ± 0.056	3.9AspGly: 3.9 ± 0.091	0.989AspHis: 0.989 ± 0.029	4.617AspIle: 4.617 ± 0.083	4.14AspLys: 4.14 ± 0.069	5.585AspLeu: 5.585 ± 0.072	1.514AspMet: 1.514 ± 0.039	3.033AspAsn: 3.033 ± 0.065	1.839AspPro: 1.839 ± 0.044	1.94AspGln: 1.94 ± 0.046	1.885AspArg: 1.885 ± 0.049	3.827AspSer: 3.827 ± 0.071	2.961AspThr: 2.961 ± 0.059	4.479AspVal: 4.479 ± 0.076	0.819AspTrp: 0.819 ± 0.031	2.128AspTyr: 2.128 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	4.414GluAla: 4.414 ± 0.081	0.42GluCys: 0.42 ± 0.021	3.124GluAsp: 3.124 ± 0.066	3.308GluGlu: 3.308 ± 0.077	2.944GluPhe: 2.944 ± 0.051	3.017GluGly: 3.017 ± 0.059	1.533GluHis: 1.533 ± 0.043	4.273GluIle: 4.273 ± 0.069	3.997GluLys: 3.997 ± 0.071	7.777GluLeu: 7.777 ± 0.092	1.626GluMet: 1.626 ± 0.038	3.103GluAsn: 3.103 ± 0.053	1.803GluPro: 1.803 ± 0.054	4.255GluGln: 4.255 ± 0.079	2.56GluArg: 2.56 ± 0.057	4.058GluSer: 4.058 ± 0.062	3.227GluThr: 3.227 ± 0.071	4.003GluVal: 4.003 ± 0.063	0.581GluTrp: 0.581 ± 0.025	2.015GluTyr: 2.015 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.409PheAla: 3.409 ± 0.06	0.463PheCys: 0.463 ± 0.022	3.078PheAsp: 3.078 ± 0.058	2.821PheGlu: 2.821 ± 0.054	1.773PhePhe: 1.773 ± 0.044	3.178PheGly: 3.178 ± 0.062	0.799PheHis: 0.799 ± 0.027	3.358PheIle: 3.358 ± 0.071	2.565PheLys: 2.565 ± 0.051	3.499PheLeu: 3.499 ± 0.076	1.017PheMet: 1.017 ± 0.032	2.742PheAsn: 2.742 ± 0.057	1.38PhePro: 1.38 ± 0.038	1.243PheGln: 1.243 ± 0.029	1.346PheArg: 1.346 ± 0.04	3.625PheSer: 3.625 ± 0.066	2.638PheThr: 2.638 ± 0.049	2.99PheVal: 2.99 ± 0.054	0.491PheTrp: 0.491 ± 0.023	1.574PheTyr: 1.574 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	4.59GlyAla: 4.59 ± 0.089	0.711GlyCys: 0.711 ± 0.028	3.647GlyAsp: 3.647 ± 0.07	3.879GlyGlu: 3.879 ± 0.063	3.356GlyPhe: 3.356 ± 0.067	4.25GlyGly: 4.25 ± 0.087	1.385GlyHis: 1.385 ± 0.048	4.646GlyIle: 4.646 ± 0.072	4.144GlyLys: 4.144 ± 0.072	6.608GlyLeu: 6.608 ± 0.085	1.733GlyMet: 1.733 ± 0.048	2.699GlyAsn: 2.699 ± 0.054	1.383GlyPro: 1.383 ± 0.033	2.506GlyGln: 2.506 ± 0.052	2.454GlyArg: 2.454 ± 0.052	3.988GlySer: 3.988 ± 0.075	3.306GlyThr: 3.306 ± 0.07	4.641GlyVal: 4.641 ± 0.08	0.826GlyTrp: 0.826 ± 0.033	2.416GlyTyr: 2.416 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.271HisAla: 1.271 ± 0.039	0.259HisCys: 0.259 ± 0.016	1.013HisAsp: 1.013 ± 0.031	1.01HisGlu: 1.01 ± 0.031	1.03HisPhe: 1.03 ± 0.03	1.29HisGly: 1.29 ± 0.033	0.538HisHis: 0.538 ± 0.028	1.461HisIle: 1.461 ± 0.043	1.26HisLys: 1.26 ± 0.039	2.019HisLeu: 2.019 ± 0.047	0.443HisMet: 0.443 ± 0.018	0.968HisAsn: 0.968 ± 0.031	0.952HisPro: 0.952 ± 0.03	1.001HisGln: 1.001 ± 0.031	0.808HisArg: 0.808 ± 0.028	1.396HisSer: 1.396 ± 0.037	0.97HisThr: 0.97 ± 0.039	1.165HisVal: 1.165 ± 0.031	0.292HisTrp: 0.292 ± 0.018	0.753HisTyr: 0.753 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.043IleAla: 6.043 ± 0.095	0.699IleCys: 0.699 ± 0.027	4.631IleAsp: 4.631 ± 0.073	5.1IleGlu: 5.1 ± 0.078	2.659IlePhe: 2.659 ± 0.054	4.59IleGly: 4.59 ± 0.074	1.235IleHis: 1.235 ± 0.038	4.468IleIle: 4.468 ± 0.079	4.677IleLys: 4.677 ± 0.073	5.887IleLeu: 5.887 ± 0.099	1.479IleMet: 1.479 ± 0.039	4.085IleAsn: 4.085 ± 0.075	2.633IlePro: 2.633 ± 0.045	2.369IleGln: 2.369 ± 0.052	2.515IleArg: 2.515 ± 0.043	5.363IleSer: 5.363 ± 0.076	4.389IleThr: 4.389 ± 0.058	4.429IleVal: 4.429 ± 0.072	0.662IleTrp: 0.662 ± 0.028	2.011IleTyr: 2.011 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.988LysAla: 4.988 ± 0.081	0.359LysCys: 0.359 ± 0.022	3.455LysAsp: 3.455 ± 0.056	3.627LysGlu: 3.627 ± 0.064	2.205LysPhe: 2.205 ± 0.044	3.41LysGly: 3.41 ± 0.063	1.414LysHis: 1.414 ± 0.048	3.928LysIle: 3.928 ± 0.065	3.825LysLys: 3.825 ± 0.074	6.526LysLeu: 6.526 ± 0.09	1.57LysMet: 1.57 ± 0.036	3.174LysAsn: 3.174 ± 0.059	2.53LysPro: 2.53 ± 0.056	3.737LysGln: 3.737 ± 0.07	2.563LysArg: 2.563 ± 0.053	4.359LysSer: 4.359 ± 0.07	3.634LysThr: 3.634 ± 0.065	4.426LysVal: 4.426 ± 0.063	0.651LysTrp: 0.651 ± 0.024	1.936LysTyr: 1.936 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	8.88LeuAla: 8.88 ± 0.117	0.868LeuCys: 0.868 ± 0.032	5.955LeuAsp: 5.955 ± 0.089	5.885LeuGlu: 5.885 ± 0.09	4.517LeuPhe: 4.517 ± 0.076	6.283LeuGly: 6.283 ± 0.089	1.811LeuHis: 1.811 ± 0.042	6.931LeuIle: 6.931 ± 0.093	5.924LeuLys: 5.924 ± 0.094	10.151LeuLeu: 10.151 ± 0.139	2.508LeuMet: 2.508 ± 0.054	5.542LeuAsn: 5.542 ± 0.079	4.212LeuPro: 4.212 ± 0.058	3.577LeuGln: 3.577 ± 0.071	3.359LeuArg: 3.359 ± 0.064	8.063LeuSer: 8.063 ± 0.099	6.89LeuThr: 6.89 ± 0.089	7.061LeuVal: 7.061 ± 0.097	0.89LeuTrp: 0.89 ± 0.03	2.659LeuTyr: 2.659 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.177MetAla: 2.177 ± 0.052	0.166MetCys: 0.166 ± 0.011	1.24MetAsp: 1.24 ± 0.038	1.257MetGlu: 1.257 ± 0.042	1.108MetPhe: 1.108 ± 0.045	1.52MetGly: 1.52 ± 0.047	0.422MetHis: 0.422 ± 0.021	1.34MetIle: 1.34 ± 0.041	1.558MetLys: 1.558 ± 0.039	2.64MetLeu: 2.64 ± 0.054	0.672MetMet: 0.672 ± 0.031	1.153MetAsn: 1.153 ± 0.034	1.141MetPro: 1.141 ± 0.032	1.051MetGln: 1.051 ± 0.037	0.963MetArg: 0.963 ± 0.03	1.995MetSer: 1.995 ± 0.04	1.593MetThr: 1.593 ± 0.043	1.507MetVal: 1.507 ± 0.035	0.226MetTrp: 0.226 ± 0.014	0.606MetTyr: 0.606 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.728AsnAla: 3.728 ± 0.068	0.468AsnCys: 0.468 ± 0.022	3.002AsnAsp: 3.002 ± 0.066	2.954AsnGlu: 2.954 ± 0.056	1.872AsnPhe: 1.872 ± 0.043	3.281AsnGly: 3.281 ± 0.061	0.952AsnHis: 0.952 ± 0.029	3.712AsnIle: 3.712 ± 0.056	3.677AsnLys: 3.677 ± 0.069	4.677AsnLeu: 4.677 ± 0.063	1.247AsnMet: 1.247 ± 0.038	2.926AsnAsn: 2.926 ± 0.063	2.028AsnPro: 2.028 ± 0.042	2.375AsnGln: 2.375 ± 0.067	1.884AsnArg: 1.884 ± 0.048	3.509AsnSer: 3.509 ± 0.066	3.01AsnThr: 3.01 ± 0.059	3.395AsnVal: 3.395 ± 0.065	0.724AsnTrp: 0.724 ± 0.028	1.702AsnTyr: 1.702 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	2.567ProAla: 2.567 ± 0.059	0.247ProCys: 0.247 ± 0.017	2.233ProAsp: 2.233 ± 0.048	2.975ProGlu: 2.975 ± 0.058	1.638ProPhe: 1.638 ± 0.043	1.849ProGly: 1.849 ± 0.048	0.683ProHis: 0.683 ± 0.024	2.676ProIle: 2.676 ± 0.059	2.071ProLys: 2.071 ± 0.048	3.53ProLeu: 3.53 ± 0.062	0.834ProMet: 0.834 ± 0.03	1.868ProAsn: 1.868 ± 0.043	0.86ProPro: 0.86 ± 0.036	1.353ProGln: 1.353 ± 0.037	1.018ProArg: 1.018 ± 0.032	2.3ProSer: 2.3 ± 0.054	2.043ProThr: 2.043 ± 0.043	2.688ProVal: 2.688 ± 0.055	0.395ProTrp: 0.395 ± 0.018	1.187ProTyr: 1.187 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.781GlnAla: 3.781 ± 0.064	0.318GlnCys: 0.318 ± 0.017	2.224GlnAsp: 2.224 ± 0.049	2.4GlnGlu: 2.4 ± 0.058	1.796GlnPhe: 1.796 ± 0.04	2.562GlnGly: 2.562 ± 0.055	1.082GlnHis: 1.082 ± 0.037	2.859GlnIle: 2.859 ± 0.057	2.397GlnLys: 2.397 ± 0.055	5.121GlnLeu: 5.121 ± 0.082	0.979GlnMet: 0.979 ± 0.034	1.909GlnAsn: 1.909 ± 0.047	1.413GlnPro: 1.413 ± 0.043	2.94GlnGln: 2.94 ± 0.081	1.772GlnArg: 1.772 ± 0.046	2.812GlnSer: 2.812 ± 0.064	2.458GlnThr: 2.458 ± 0.049	3.132GlnVal: 3.132 ± 0.052	0.562GlnTrp: 0.562 ± 0.023	1.451GlnTyr: 1.451 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.551ArgAla: 2.551 ± 0.052	0.305ArgCys: 0.305 ± 0.017	2.073ArgAsp: 2.073 ± 0.049	2.31ArgGlu: 2.31 ± 0.051	1.852ArgPhe: 1.852 ± 0.051	2.174ArgGly: 2.174 ± 0.049	0.807ArgHis: 0.807 ± 0.029	2.563ArgIle: 2.563 ± 0.055	2.206ArgLys: 2.206 ± 0.048	4.069ArgLeu: 4.069 ± 0.076	0.954ArgMet: 0.954 ± 0.031	1.723ArgAsn: 1.723 ± 0.036	1.271ArgPro: 1.271 ± 0.039	1.581ArgGln: 1.581 ± 0.039	1.612ArgArg: 1.612 ± 0.04	2.286ArgSer: 2.286 ± 0.05	1.838ArgThr: 1.838 ± 0.044	2.615ArgVal: 2.615 ± 0.053	0.446ArgTrp: 0.446 ± 0.023	1.424ArgTyr: 1.424 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.516SerAla: 5.516 ± 0.075	0.618SerCys: 0.618 ± 0.026	4.198SerAsp: 4.198 ± 0.073	4.369SerGlu: 4.369 ± 0.069	3.356SerPhe: 3.356 ± 0.054	4.814SerGly: 4.814 ± 0.081	1.383SerHis: 1.383 ± 0.036	5.049SerIle: 5.049 ± 0.08	4.11SerLys: 4.11 ± 0.068	7.208SerLeu: 7.208 ± 0.095	1.654SerMet: 1.654 ± 0.045	3.603SerAsn: 3.603 ± 0.077	2.353SerPro: 2.353 ± 0.049	2.989SerGln: 2.989 ± 0.057	2.479SerArg: 2.479 ± 0.049	5.249SerSer: 5.249 ± 0.09	3.752SerThr: 3.752 ± 0.072	4.893SerVal: 4.893 ± 0.079	0.829SerTrp: 0.829 ± 0.034	2.383SerTyr: 2.383 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	4.493ThrAla: 4.493 ± 0.069	0.479ThrCys: 0.479 ± 0.023	3.613ThrAsp: 3.613 ± 0.072	3.626ThrGlu: 3.626 ± 0.069	2.287ThrPhe: 2.287 ± 0.047	4.066ThrGly: 4.066 ± 0.07	1.14ThrHis: 1.14 ± 0.035	3.829ThrIle: 3.829 ± 0.062	3.341ThrLys: 3.341 ± 0.06	5.982ThrLeu: 5.982 ± 0.089	1.083ThrMet: 1.083 ± 0.032	2.848ThrAsn: 2.848 ± 0.067	2.577ThrPro: 2.577 ± 0.049	2.378ThrGln: 2.378 ± 0.049	1.961ThrArg: 1.961 ± 0.048	4.127ThrSer: 4.127 ± 0.07	3.143ThrThr: 3.143 ± 0.062	3.789ThrVal: 3.789 ± 0.064	0.604ThrTrp: 0.604 ± 0.024	1.684ThrTyr: 1.684 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.54ValAla: 5.54 ± 0.082	0.664ValCys: 0.664 ± 0.026	4.197ValAsp: 4.197 ± 0.068	4.599ValGlu: 4.599 ± 0.08	3.014ValPhe: 3.014 ± 0.064	4.322ValGly: 4.322 ± 0.064	1.122ValHis: 1.122 ± 0.037	5.187ValIle: 5.187 ± 0.079	4.239ValLys: 4.239 ± 0.07	6.599ValLeu: 6.599 ± 0.076	1.793ValMet: 1.793 ± 0.043	3.664ValAsn: 3.664 ± 0.064	2.208ValPro: 2.208 ± 0.05	2.233ValGln: 2.233 ± 0.049	2.435ValArg: 2.435 ± 0.054	5.008ValSer: 5.008 ± 0.078	4.344ValThr: 4.344 ± 0.074	4.986ValVal: 4.986 ± 0.082	0.649ValTrp: 0.649 ± 0.025	1.859ValTyr: 1.859 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.685TrpAla: 0.685 ± 0.026	0.141TrpCys: 0.141 ± 0.014	0.685TrpAsp: 0.685 ± 0.038	0.461TrpGlu: 0.461 ± 0.023	0.592TrpPhe: 0.592 ± 0.026	0.688TrpGly: 0.688 ± 0.027	0.281TrpHis: 0.281 ± 0.016	0.672TrpIle: 0.672 ± 0.026	0.468TrpLys: 0.468 ± 0.024	1.569TrpLeu: 1.569 ± 0.044	0.273TrpMet: 0.273 ± 0.016	0.47TrpAsn: 0.47 ± 0.022	0.383TrpPro: 0.383 ± 0.019	0.885TrpGln: 0.885 ± 0.031	0.515TrpArg: 0.515 ± 0.023	0.675TrpSer: 0.675 ± 0.03	0.466TrpThr: 0.466 ± 0.022	0.729TrpVal: 0.729 ± 0.03	0.146TrpTrp: 0.146 ± 0.013	0.38TrpTyr: 0.38 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.18TyrAla: 2.18 ± 0.043	0.364TyrCys: 0.364 ± 0.022	1.792TyrAsp: 1.792 ± 0.048	1.683TyrGlu: 1.683 ± 0.042	1.605TyrPhe: 1.605 ± 0.038	2.043TyrGly: 2.043 ± 0.04	0.687TyrHis: 0.687 ± 0.025	1.958TyrIle: 1.958 ± 0.048	1.91TyrLys: 1.91 ± 0.047	3.482TyrLeu: 3.482 ± 0.064	0.684TyrMet: 0.684 ± 0.026	1.431TyrAsn: 1.431 ± 0.041	1.281TyrPro: 1.281 ± 0.037	1.849TyrGln: 1.849 ± 0.046	1.376TyrArg: 1.376 ± 0.04	2.379TyrSer: 2.379 ± 0.053	1.659TyrThr: 1.659 ± 0.048	1.863TyrVal: 1.863 ± 0.049	0.473TyrTrp: 0.473 ± 0.02	1.104TyrTyr: 1.104 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3139 proteins (1031951 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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