Amino acid dipepetide frequency for Gordonia malaquae NBRC 108250

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.232AlaAla: 19.232 ± 0.201	0.914AlaCys: 0.914 ± 0.03	9.543AlaAsp: 9.543 ± 0.089	7.18AlaGlu: 7.18 ± 0.087	3.565AlaPhe: 3.565 ± 0.053	11.205AlaGly: 11.205 ± 0.103	2.441AlaHis: 2.441 ± 0.045	5.159AlaIle: 5.159 ± 0.07	3.013AlaLys: 3.013 ± 0.057	12.124AlaLeu: 12.124 ± 0.105	2.797AlaMet: 2.797 ± 0.048	2.327AlaAsn: 2.327 ± 0.05	6.018AlaPro: 6.018 ± 0.088	3.649AlaGln: 3.649 ± 0.058	8.503AlaArg: 8.503 ± 0.102	7.038AlaSer: 7.038 ± 0.083	7.22AlaThr: 7.22 ± 0.078	12.343AlaVal: 12.343 ± 0.13	1.607AlaTrp: 1.607 ± 0.036	2.303AlaTyr: 2.303 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.91CysAla: 0.91 ± 0.032	0.075CysCys: 0.075 ± 0.009	0.466CysAsp: 0.466 ± 0.018	0.347CysGlu: 0.347 ± 0.015	0.205CysPhe: 0.205 ± 0.013	0.875CysGly: 0.875 ± 0.028	0.145CysHis: 0.145 ± 0.01	0.257CysIle: 0.257 ± 0.014	0.126CysLys: 0.126 ± 0.011	0.547CysLeu: 0.547 ± 0.022	0.138CysMet: 0.138 ± 0.011	0.14CysAsn: 0.14 ± 0.009	0.389CysPro: 0.389 ± 0.019	0.158CysGln: 0.158 ± 0.011	0.511CysArg: 0.511 ± 0.023	0.491CysSer: 0.491 ± 0.021	0.446CysThr: 0.446 ± 0.021	0.582CysVal: 0.582 ± 0.021	0.107CysTrp: 0.107 ± 0.01	0.128CysTyr: 0.128 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.79AspAla: 8.79 ± 0.1	0.401AspCys: 0.401 ± 0.019	5.571AspAsp: 5.571 ± 0.082	4.474AspGlu: 4.474 ± 0.066	1.917AspPhe: 1.917 ± 0.037	6.596AspGly: 6.596 ± 0.073	1.526AspHis: 1.526 ± 0.039	2.474AspIle: 2.474 ± 0.043	1.42AspLys: 1.42 ± 0.038	6.857AspLeu: 6.857 ± 0.078	1.154AspMet: 1.154 ± 0.026	1.219AspAsn: 1.219 ± 0.032	4.298AspPro: 4.298 ± 0.054	1.736AspGln: 1.736 ± 0.041	5.147AspArg: 5.147 ± 0.067	3.375AspSer: 3.375 ± 0.05	3.329AspThr: 3.329 ± 0.052	6.674AspVal: 6.674 ± 0.073	1.02AspTrp: 1.02 ± 0.028	1.449AspTyr: 1.449 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	5.855GluAla: 5.855 ± 0.072	0.314GluCys: 0.314 ± 0.018	2.19GluAsp: 2.19 ± 0.048	2.238GluGlu: 2.238 ± 0.051	1.847GluPhe: 1.847 ± 0.036	3.276GluGly: 3.276 ± 0.053	1.375GluHis: 1.375 ± 0.034	2.657GluIle: 2.657 ± 0.055	1.536GluLys: 1.536 ± 0.056	6.132GluLeu: 6.132 ± 0.087	1.138GluMet: 1.138 ± 0.028	1.216GluAsn: 1.216 ± 0.031	2.784GluPro: 2.784 ± 0.054	1.994GluGln: 1.994 ± 0.039	4.34GluArg: 4.34 ± 0.075	3.129GluSer: 3.129 ± 0.048	2.858GluThr: 2.858 ± 0.049	4.184GluVal: 4.184 ± 0.06	0.817GluTrp: 0.817 ± 0.026	1.182GluTyr: 1.182 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.114PheAla: 4.114 ± 0.059	0.261PheCys: 0.261 ± 0.015	2.617PheAsp: 2.617 ± 0.044	1.439PheGlu: 1.439 ± 0.034	0.891PhePhe: 0.891 ± 0.033	3.519PheGly: 3.519 ± 0.053	0.613PheHis: 0.613 ± 0.023	1.084PheIle: 1.084 ± 0.033	0.498PheLys: 0.498 ± 0.022	2.444PheLeu: 2.444 ± 0.05	0.49PheMet: 0.49 ± 0.019	0.693PheAsn: 0.693 ± 0.024	1.337PhePro: 1.337 ± 0.03	0.629PheGln: 0.629 ± 0.023	1.629PheArg: 1.629 ± 0.04	1.699PheSer: 1.699 ± 0.036	2.209PheThr: 2.209 ± 0.038	2.787PheVal: 2.787 ± 0.049	0.387PheTrp: 0.387 ± 0.019	0.663PheTyr: 0.663 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.982GlyAla: 9.982 ± 0.098	0.68GlyCys: 0.68 ± 0.025	5.775GlyAsp: 5.775 ± 0.069	4.389GlyGlu: 4.389 ± 0.056	3.106GlyPhe: 3.106 ± 0.049	7.633GlyGly: 7.633 ± 0.086	1.876GlyHis: 1.876 ± 0.042	3.911GlyIle: 3.911 ± 0.057	2.409GlyLys: 2.409 ± 0.045	8.492GlyLeu: 8.492 ± 0.096	1.999GlyMet: 1.999 ± 0.04	1.678GlyAsn: 1.678 ± 0.04	4.27GlyPro: 4.27 ± 0.06	2.506GlyGln: 2.506 ± 0.049	6.569GlyArg: 6.569 ± 0.077	5.43GlySer: 5.43 ± 0.076	5.389GlyThr: 5.389 ± 0.071	8.606GlyVal: 8.606 ± 0.084	1.52GlyTrp: 1.52 ± 0.039	2.255GlyTyr: 2.255 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.274HisAla: 2.274 ± 0.044	0.179HisCys: 0.179 ± 0.012	1.412HisAsp: 1.412 ± 0.03	0.974HisGlu: 0.974 ± 0.027	0.61HisPhe: 0.61 ± 0.025	1.886HisGly: 1.886 ± 0.039	0.61HisHis: 0.61 ± 0.021	0.748HisIle: 0.748 ± 0.021	0.368HisLys: 0.368 ± 0.019	1.985HisLeu: 1.985 ± 0.04	0.346HisMet: 0.346 ± 0.017	0.437HisAsn: 0.437 ± 0.017	1.453HisPro: 1.453 ± 0.033	0.538HisGln: 0.538 ± 0.023	1.811HisArg: 1.811 ± 0.039	1.102HisSer: 1.102 ± 0.032	1.135HisThr: 1.135 ± 0.032	1.762HisVal: 1.762 ± 0.04	0.3HisTrp: 0.3 ± 0.014	0.466HisTyr: 0.466 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.777IleAla: 6.777 ± 0.069	0.327IleCys: 0.327 ± 0.015	3.682IleAsp: 3.682 ± 0.049	2.442IleGlu: 2.442 ± 0.048	0.906IlePhe: 0.906 ± 0.028	4.91IleGly: 4.91 ± 0.064	0.76IleHis: 0.76 ± 0.024	1.549IleIle: 1.549 ± 0.042	0.867IleLys: 0.867 ± 0.028	3.349IleLeu: 3.349 ± 0.059	0.647IleMet: 0.647 ± 0.025	1.073IleAsn: 1.073 ± 0.029	2.235IlePro: 2.235 ± 0.041	0.774IleGln: 0.774 ± 0.026	2.679IleArg: 2.679 ± 0.04	2.369IleSer: 2.369 ± 0.037	2.983IleThr: 2.983 ± 0.041	4.566IleVal: 4.566 ± 0.06	0.415IleTrp: 0.415 ± 0.019	0.677IleTyr: 0.677 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.891LysAla: 2.891 ± 0.064	0.116LysCys: 0.116 ± 0.01	1.191LysAsp: 1.191 ± 0.03	0.922LysGlu: 0.922 ± 0.03	0.632LysPhe: 0.632 ± 0.022	1.692LysGly: 1.692 ± 0.036	0.5LysHis: 0.5 ± 0.018	1.134LysIle: 1.134 ± 0.03	0.889LysLys: 0.889 ± 0.039	2.081LysLeu: 2.081 ± 0.047	0.549LysMet: 0.549 ± 0.02	0.66LysAsn: 0.66 ± 0.027	1.464LysPro: 1.464 ± 0.047	0.719LysGln: 0.719 ± 0.025	1.654LysArg: 1.654 ± 0.037	1.376LysSer: 1.376 ± 0.038	1.464LysThr: 1.464 ± 0.035	2.092LysVal: 2.092 ± 0.046	0.346LysTrp: 0.346 ± 0.014	0.54LysTyr: 0.54 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	13.103LeuAla: 13.103 ± 0.111	0.674LeuCys: 0.674 ± 0.023	6.916LeuAsp: 6.916 ± 0.091	4.091LeuGlu: 4.091 ± 0.06	2.563LeuPhe: 2.563 ± 0.05	8.341LeuGly: 8.341 ± 0.081	1.826LeuHis: 1.826 ± 0.039	4.46LeuIle: 4.46 ± 0.064	1.821LeuLys: 1.821 ± 0.042	8.646LeuLeu: 8.646 ± 0.109	1.757LeuMet: 1.757 ± 0.04	1.858LeuAsn: 1.858 ± 0.041	5.286LeuPro: 5.286 ± 0.061	2.113LeuGln: 2.113 ± 0.042	6.928LeuArg: 6.928 ± 0.075	5.77LeuSer: 5.77 ± 0.064	6.507LeuThr: 6.507 ± 0.062	8.426LeuVal: 8.426 ± 0.085	1.141LeuTrp: 1.141 ± 0.031	1.561LeuTyr: 1.561 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.335MetAla: 2.335 ± 0.042	0.159MetCys: 0.159 ± 0.011	0.92MetAsp: 0.92 ± 0.025	0.73MetGlu: 0.73 ± 0.025	0.674MetPhe: 0.674 ± 0.025	1.449MetGly: 1.449 ± 0.039	0.392MetHis: 0.392 ± 0.02	1.097MetIle: 1.097 ± 0.031	0.518MetLys: 0.518 ± 0.021	1.996MetLeu: 1.996 ± 0.041	0.441MetMet: 0.441 ± 0.018	0.572MetAsn: 0.572 ± 0.024	1.195MetPro: 1.195 ± 0.031	0.49MetGln: 0.49 ± 0.021	1.593MetArg: 1.593 ± 0.032	1.791MetSer: 1.791 ± 0.035	2.016MetThr: 2.016 ± 0.041	1.589MetVal: 1.589 ± 0.038	0.278MetTrp: 0.278 ± 0.015	0.358MetTyr: 0.358 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.477AsnAla: 2.477 ± 0.053	0.163AsnCys: 0.163 ± 0.01	1.292AsnAsp: 1.292 ± 0.031	0.959AsnGlu: 0.959 ± 0.029	0.593AsnPhe: 0.593 ± 0.022	2.174AsnGly: 2.174 ± 0.052	0.424AsnHis: 0.424 ± 0.02	0.888AsnIle: 0.888 ± 0.027	0.525AsnLys: 0.525 ± 0.021	1.919AsnLeu: 1.919 ± 0.045	0.38AsnMet: 0.38 ± 0.017	0.557AsnAsn: 0.557 ± 0.024	1.629AsnPro: 1.629 ± 0.039	0.581AsnGln: 0.581 ± 0.021	1.632AsnArg: 1.632 ± 0.038	1.157AsnSer: 1.157 ± 0.031	1.277AsnThr: 1.277 ± 0.029	1.842AsnVal: 1.842 ± 0.045	0.314AsnTrp: 0.314 ± 0.017	0.477AsnTyr: 0.477 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.717ProAla: 6.717 ± 0.091	0.261ProCys: 0.261 ± 0.015	4.388ProAsp: 4.388 ± 0.056	3.362ProGlu: 3.362 ± 0.044	1.591ProPhe: 1.591 ± 0.034	5.081ProGly: 5.081 ± 0.058	1.057ProHis: 1.057 ± 0.028	2.331ProIle: 2.331 ± 0.042	1.295ProLys: 1.295 ± 0.04	4.403ProLeu: 4.403 ± 0.056	1.16ProMet: 1.16 ± 0.028	1.258ProAsn: 1.258 ± 0.034	2.481ProPro: 2.481 ± 0.054	1.528ProGln: 1.528 ± 0.038	3.173ProArg: 3.173 ± 0.05	3.474ProSer: 3.474 ± 0.05	3.698ProThr: 3.698 ± 0.059	4.79ProVal: 4.79 ± 0.072	0.785ProTrp: 0.785 ± 0.026	0.99ProTyr: 0.99 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.18GlnAla: 3.18 ± 0.048	0.184GlnCys: 0.184 ± 0.014	1.058GlnAsp: 1.058 ± 0.03	1.055GlnGlu: 1.055 ± 0.027	0.901GlnPhe: 0.901 ± 0.029	1.787GlnGly: 1.787 ± 0.044	0.56GlnHis: 0.56 ± 0.021	1.495GlnIle: 1.495 ± 0.029	0.671GlnLys: 0.671 ± 0.025	2.655GlnLeu: 2.655 ± 0.048	0.648GlnMet: 0.648 ± 0.021	0.642GlnAsn: 0.642 ± 0.022	1.461GlnPro: 1.461 ± 0.045	1.105GlnGln: 1.105 ± 0.043	2.292GlnArg: 2.292 ± 0.042	1.55GlnSer: 1.55 ± 0.032	1.643GlnThr: 1.643 ± 0.038	2.437GlnVal: 2.437 ± 0.046	0.52GlnTrp: 0.52 ± 0.018	0.628GlnTyr: 0.628 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	8.12ArgAla: 8.12 ± 0.098	0.485ArgCys: 0.485 ± 0.019	4.586ArgAsp: 4.586 ± 0.062	3.902ArgGlu: 3.902 ± 0.054	2.316ArgPhe: 2.316 ± 0.044	5.261ArgGly: 5.261 ± 0.068	1.571ArgHis: 1.571 ± 0.034	3.561ArgIle: 3.561 ± 0.053	1.692ArgLys: 1.692 ± 0.045	7.152ArgLeu: 7.152 ± 0.089	1.819ArgMet: 1.819 ± 0.035	1.531ArgAsn: 1.531 ± 0.039	3.88ArgPro: 3.88 ± 0.061	1.937ArgGln: 1.937 ± 0.04	6.662ArgArg: 6.662 ± 0.086	4.374ArgSer: 4.374 ± 0.055	4.555ArgThr: 4.555 ± 0.056	5.857ArgVal: 5.857 ± 0.079	1.196ArgTrp: 1.196 ± 0.032	1.626ArgTyr: 1.626 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	7.356SerAla: 7.356 ± 0.092	0.418SerCys: 0.418 ± 0.016	4.208SerAsp: 4.208 ± 0.062	2.888SerGlu: 2.888 ± 0.052	1.737SerPhe: 1.737 ± 0.038	6.064SerGly: 6.064 ± 0.075	1.079SerHis: 1.079 ± 0.026	2.609SerIle: 2.609 ± 0.044	1.344SerLys: 1.344 ± 0.033	5.116SerLeu: 5.116 ± 0.069	1.455SerMet: 1.455 ± 0.034	1.261SerAsn: 1.261 ± 0.03	3.165SerPro: 3.165 ± 0.052	1.432SerGln: 1.432 ± 0.032	3.956SerArg: 3.956 ± 0.058	3.886SerSer: 3.886 ± 0.069	4.363SerThr: 4.363 ± 0.067	5.186SerVal: 5.186 ± 0.074	0.889SerTrp: 0.889 ± 0.027	1.127SerTyr: 1.127 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	8.277ThrAla: 8.277 ± 0.096	0.442ThrCys: 0.442 ± 0.018	4.253ThrAsp: 4.253 ± 0.053	3.094ThrGlu: 3.094 ± 0.051	1.911ThrPhe: 1.911 ± 0.039	6.049ThrGly: 6.049 ± 0.077	1.118ThrHis: 1.118 ± 0.033	2.81ThrIle: 2.81 ± 0.046	1.381ThrLys: 1.381 ± 0.037	5.526ThrLeu: 5.526 ± 0.068	1.258ThrMet: 1.258 ± 0.029	1.225ThrAsn: 1.225 ± 0.031	3.955ThrPro: 3.955 ± 0.059	1.441ThrGln: 1.441 ± 0.032	3.871ThrArg: 3.871 ± 0.052	4.024ThrSer: 4.024 ± 0.06	4.267ThrThr: 4.267 ± 0.07	6.618ThrVal: 6.618 ± 0.072	0.919ThrTrp: 0.919 ± 0.026	1.303ThrTyr: 1.303 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	11.959ValAla: 11.959 ± 0.129	0.687ValCys: 0.687 ± 0.022	7.259ValAsp: 7.259 ± 0.097	5.032ValGlu: 5.032 ± 0.1	2.752ValPhe: 2.752 ± 0.045	7.743ValGly: 7.743 ± 0.086	1.877ValHis: 1.877 ± 0.036	4.306ValIle: 4.306 ± 0.057	1.801ValLys: 1.801 ± 0.042	8.772ValLeu: 8.772 ± 0.096	1.732ValMet: 1.732 ± 0.038	2.034ValAsn: 2.034 ± 0.036	4.742ValPro: 4.742 ± 0.064	2.003ValGln: 2.003 ± 0.04	6.152ValArg: 6.152 ± 0.072	5.28ValSer: 5.28 ± 0.068	6.138ValThr: 6.138 ± 0.072	9.536ValVal: 9.536 ± 0.113	1.161ValTrp: 1.161 ± 0.029	1.675ValTyr: 1.675 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.556TrpAla: 1.556 ± 0.039	0.123TrpCys: 0.123 ± 0.01	0.765TrpAsp: 0.765 ± 0.027	0.6TrpGlu: 0.6 ± 0.021	0.554TrpPhe: 0.554 ± 0.022	1.001TrpGly: 1.001 ± 0.033	0.318TrpHis: 0.318 ± 0.016	0.761TrpIle: 0.761 ± 0.021	0.325TrpLys: 0.325 ± 0.016	1.501TrpLeu: 1.501 ± 0.035	0.372TrpMet: 0.372 ± 0.017	0.416TrpAsn: 0.416 ± 0.018	0.713TrpPro: 0.713 ± 0.027	0.522TrpGln: 0.522 ± 0.021	1.18TrpArg: 1.18 ± 0.029	0.957TrpSer: 0.957 ± 0.029	0.988TrpThr: 0.988 ± 0.03	1.09TrpVal: 1.09 ± 0.033	0.353TrpTrp: 0.353 ± 0.018	0.317TrpTyr: 0.317 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.275TyrAla: 2.275 ± 0.04	0.181TyrCys: 0.181 ± 0.012	1.336TyrAsp: 1.336 ± 0.036	0.946TyrGlu: 0.946 ± 0.028	0.73TyrPhe: 0.73 ± 0.023	1.933TyrGly: 1.933 ± 0.043	0.329TyrHis: 0.329 ± 0.013	0.698TyrIle: 0.698 ± 0.025	0.412TyrLys: 0.412 ± 0.018	2.09TyrLeu: 2.09 ± 0.044	0.314TyrMet: 0.314 ± 0.017	0.462TyrAsn: 0.462 ± 0.019	1.067TyrPro: 1.067 ± 0.03	0.616TyrGln: 0.616 ± 0.026	1.802TyrArg: 1.802 ± 0.037	1.268TyrSer: 1.268 ± 0.031	1.256TyrThr: 1.256 ± 0.033	1.674TyrVal: 1.674 ± 0.038	0.336TyrTrp: 0.336 ± 0.015	0.428TyrTyr: 0.428 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4269 proteins (1358179 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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