Amino acid dipepetide frequency for Macaca mulatta feces associated virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
4.219AlaCys: 4.219 ± 2.415
1.406AlaAsp: 1.406 ± 0.805
2.813AlaGlu: 2.813 ± 0.941
1.406AlaPhe: 1.406 ± 1.227
8.439AlaGly: 8.439 ± 2.499
1.406AlaHis: 1.406 ± 1.227
0.0AlaIle: 0.0 ± 0.0
2.813AlaLys: 2.813 ± 1.61
2.813AlaLeu: 2.813 ± 1.61
7.032AlaMet: 7.032 ± 2.507
2.813AlaAsn: 2.813 ± 0.941
1.406AlaPro: 1.406 ± 0.805
0.0AlaGln: 0.0 ± 0.0
0.0AlaArg: 0.0 ± 0.0
5.626AlaSer: 5.626 ± 3.22
8.439AlaThr: 8.439 ± 4.831
1.406AlaVal: 1.406 ± 0.805
1.406AlaTrp: 1.406 ± 1.856
2.813AlaTyr: 2.813 ± 0.941
0.0AlaXaa: 0.0 ± 0.0
Cys
1.406CysAla: 1.406 ± 0.805
2.813CysCys: 2.813 ± 2.02
2.813CysAsp: 2.813 ± 1.61
0.0CysGlu: 0.0 ± 0.0
1.406CysPhe: 1.406 ± 0.805
0.0CysGly: 0.0 ± 0.0
1.406CysHis: 1.406 ± 1.227
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
4.219CysLeu: 4.219 ± 5.567
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.406CysSer: 1.406 ± 0.805
1.406CysThr: 1.406 ± 1.856
1.406CysVal: 1.406 ± 1.227
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.406AspAla: 1.406 ± 0.805
1.406AspCys: 1.406 ± 0.805
0.0AspAsp: 0.0 ± 0.0
1.406AspGlu: 1.406 ± 1.227
0.0AspPhe: 0.0 ± 0.0
1.406AspGly: 1.406 ± 0.805
1.406AspHis: 1.406 ± 1.227
1.406AspIle: 1.406 ± 0.805
2.813AspLys: 2.813 ± 1.61
8.439AspLeu: 8.439 ± 0.55
1.406AspMet: 1.406 ± 0.805
2.813AspAsn: 2.813 ± 1.61
1.406AspPro: 1.406 ± 0.805
0.0AspGln: 0.0 ± 0.0
4.219AspArg: 4.219 ± 3.68
2.813AspSer: 2.813 ± 1.486
4.219AspThr: 4.219 ± 2.415
4.219AspVal: 4.219 ± 1.249
0.0AspTrp: 0.0 ± 0.0
1.406AspTyr: 1.406 ± 0.805
0.0AspXaa: 0.0 ± 0.0
Glu
2.813GluAla: 2.813 ± 1.61
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
1.406GluPhe: 1.406 ± 0.805
7.032GluGly: 7.032 ± 0.679
2.813GluHis: 2.813 ± 0.941
2.813GluIle: 2.813 ± 0.941
1.406GluLys: 1.406 ± 1.856
2.813GluLeu: 2.813 ± 0.941
0.0GluMet: 0.0 ± 0.0
1.406GluAsn: 1.406 ± 1.227
1.406GluPro: 1.406 ± 0.805
2.813GluGln: 2.813 ± 0.941
4.219GluArg: 4.219 ± 3.68
4.219GluSer: 4.219 ± 1.507
2.813GluThr: 2.813 ± 0.941
4.219GluVal: 4.219 ± 2.033
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.813PheAla: 2.813 ± 1.61
0.0PheCys: 0.0 ± 0.0
2.813PheAsp: 2.813 ± 0.941
0.0PheGlu: 0.0 ± 0.0
1.406PhePhe: 1.406 ± 0.805
1.406PheGly: 1.406 ± 0.805
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
1.406PheAsn: 1.406 ± 0.805
1.406PhePro: 1.406 ± 0.805
1.406PheGln: 1.406 ± 1.227
0.0PheArg: 0.0 ± 0.0
1.406PheSer: 1.406 ± 0.805
1.406PheThr: 1.406 ± 1.856
4.219PheVal: 4.219 ± 1.507
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.219GlyAla: 4.219 ± 2.415
1.406GlyCys: 1.406 ± 1.227
0.0GlyAsp: 0.0 ± 0.0
2.813GlyGlu: 2.813 ± 1.61
1.406GlyPhe: 1.406 ± 1.227
4.219GlyGly: 4.219 ± 2.033
2.813GlyHis: 2.813 ± 2.454
5.626GlyIle: 5.626 ± 1.881
5.626GlyLys: 5.626 ± 1.989
8.439GlyLeu: 8.439 ± 3.372
1.406GlyMet: 1.406 ± 0.805
2.813GlyAsn: 2.813 ± 1.61
2.813GlyPro: 2.813 ± 0.941
7.032GlyGln: 7.032 ± 2.06
4.219GlyArg: 4.219 ± 2.033
5.626GlySer: 5.626 ± 1.88
5.626GlyThr: 5.626 ± 1.989
5.626GlyVal: 5.626 ± 1.88
2.813GlyTrp: 2.813 ± 1.486
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
4.219HisGly: 4.219 ± 2.033
1.406HisHis: 1.406 ± 1.227
0.0HisIle: 0.0 ± 0.0
1.406HisLys: 1.406 ± 1.227
2.813HisLeu: 2.813 ± 2.454
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.813HisGln: 2.813 ± 2.454
4.219HisArg: 4.219 ± 3.68
0.0HisSer: 0.0 ± 0.0
4.219HisThr: 4.219 ± 2.033
1.406HisVal: 1.406 ± 1.227
1.406HisTrp: 1.406 ± 0.805
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.219IleAla: 4.219 ± 2.415
0.0IleCys: 0.0 ± 0.0
2.813IleAsp: 2.813 ± 0.941
0.0IleGlu: 0.0 ± 0.0
0.0IlePhe: 0.0 ± 0.0
2.813IleGly: 2.813 ± 0.941
1.406IleHis: 1.406 ± 0.805
2.813IleIle: 2.813 ± 1.486
1.406IleLys: 1.406 ± 1.227
8.439IleLeu: 8.439 ± 2.067
2.813IleMet: 2.813 ± 1.61
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
4.219IleGln: 4.219 ± 1.249
8.439IleArg: 8.439 ± 4.212
0.0IleSer: 0.0 ± 0.0
0.0IleThr: 0.0 ± 0.0
4.219IleVal: 4.219 ± 1.256
0.0IleTrp: 0.0 ± 0.0
2.813IleTyr: 2.813 ± 1.61
0.0IleXaa: 0.0 ± 0.0
Lys
4.219LysAla: 4.219 ± 2.415
0.0LysCys: 0.0 ± 0.0
1.406LysAsp: 1.406 ± 1.856
2.813LysGlu: 2.813 ± 2.02
1.406LysPhe: 1.406 ± 0.805
4.219LysGly: 4.219 ± 3.68
1.406LysHis: 1.406 ± 0.805
4.219LysIle: 4.219 ± 1.507
2.813LysLys: 2.813 ± 0.941
4.219LysLeu: 4.219 ± 5.567
1.406LysMet: 1.406 ± 0.805
4.219LysAsn: 4.219 ± 2.415
2.813LysPro: 2.813 ± 1.486
1.406LysGln: 1.406 ± 1.227
1.406LysArg: 1.406 ± 1.227
2.813LysSer: 2.813 ± 2.454
1.406LysThr: 1.406 ± 0.805
5.626LysVal: 5.626 ± 1.88
1.406LysTrp: 1.406 ± 1.856
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.219LeuAla: 4.219 ± 2.78
0.0LeuCys: 0.0 ± 0.0
7.032LeuAsp: 7.032 ± 1.217
2.813LeuGlu: 2.813 ± 2.02
0.0LeuPhe: 0.0 ± 0.0
5.626LeuGly: 5.626 ± 1.905
1.406LeuHis: 1.406 ± 1.227
2.813LeuIle: 2.813 ± 2.02
4.219LeuLys: 4.219 ± 1.507
9.845LeuLeu: 9.845 ± 10.644
2.813LeuMet: 2.813 ± 3.113
2.813LeuAsn: 2.813 ± 1.61
7.032LeuPro: 7.032 ± 2.883
5.626LeuGln: 5.626 ± 1.905
7.032LeuArg: 7.032 ± 4.904
7.032LeuSer: 7.032 ± 4.721
2.813LeuThr: 2.813 ± 1.61
12.658LeuVal: 12.658 ± 5.319
1.406LeuTrp: 1.406 ± 1.856
5.626LeuTyr: 5.626 ± 3.22
0.0LeuXaa: 0.0 ± 0.0
Met
2.813MetAla: 2.813 ± 0.941
0.0MetCys: 0.0 ± 0.0
2.813MetAsp: 2.813 ± 0.941
2.813MetGlu: 2.813 ± 0.941
2.813MetPhe: 2.813 ± 1.61
2.813MetGly: 2.813 ± 1.61
0.0MetHis: 0.0 ± 0.0
2.813MetIle: 2.813 ± 1.61
1.406MetLys: 1.406 ± 1.856
5.626MetLeu: 5.626 ± 2.972
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.813MetPro: 2.813 ± 1.61
0.0MetGln: 0.0 ± 0.0
4.219MetArg: 4.219 ± 2.415
2.813MetSer: 2.813 ± 1.486
1.406MetThr: 1.406 ± 1.856
0.0MetVal: 0.0 ± 0.0
1.406MetTrp: 1.406 ± 1.856
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.406AsnAla: 1.406 ± 0.805
0.0AsnCys: 0.0 ± 0.0
4.219AsnAsp: 4.219 ± 1.249
4.219AsnGlu: 4.219 ± 1.249
1.406AsnPhe: 1.406 ± 0.805
1.406AsnGly: 1.406 ± 0.805
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
1.406AsnLeu: 1.406 ± 0.805
1.406AsnMet: 1.406 ± 1.463
0.0AsnAsn: 0.0 ± 0.0
1.406AsnPro: 1.406 ± 0.805
4.219AsnGln: 4.219 ± 2.033
1.406AsnArg: 1.406 ± 0.805
4.219AsnSer: 4.219 ± 2.415
5.626AsnThr: 5.626 ± 2.972
4.219AsnVal: 4.219 ± 2.415
2.813AsnTrp: 2.813 ± 1.61
2.813AsnTyr: 2.813 ± 1.61
0.0AsnXaa: 0.0 ± 0.0
Pro
5.626ProAla: 5.626 ± 3.22
0.0ProCys: 0.0 ± 0.0
1.406ProAsp: 1.406 ± 0.805
2.813ProGlu: 2.813 ± 1.61
0.0ProPhe: 0.0 ± 0.0
1.406ProGly: 1.406 ± 0.805
1.406ProHis: 1.406 ± 1.227
4.219ProIle: 4.219 ± 1.507
1.406ProLys: 1.406 ± 1.227
2.813ProLeu: 2.813 ± 1.61
0.0ProMet: 0.0 ± 0.0
1.406ProAsn: 1.406 ± 0.805
2.813ProPro: 2.813 ± 0.941
5.626ProGln: 5.626 ± 2.972
9.845ProArg: 9.845 ± 5.283
4.219ProSer: 4.219 ± 2.415
4.219ProThr: 4.219 ± 1.256
1.406ProVal: 1.406 ± 1.856
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.813GlnAla: 2.813 ± 1.61
0.0GlnCys: 0.0 ± 0.0
1.406GlnAsp: 1.406 ± 0.805
1.406GlnGlu: 1.406 ± 1.227
1.406GlnPhe: 1.406 ± 0.805
4.219GlnGly: 4.219 ± 3.68
1.406GlnHis: 1.406 ± 1.227
7.032GlnIle: 7.032 ± 2.92
4.219GlnLys: 4.219 ± 3.68
1.406GlnLeu: 1.406 ± 0.805
4.219GlnMet: 4.219 ± 1.256
1.406GlnAsn: 1.406 ± 0.805
2.813GlnPro: 2.813 ± 1.61
1.406GlnGln: 1.406 ± 1.856
1.406GlnArg: 1.406 ± 1.227
4.219GlnSer: 4.219 ± 1.249
8.439GlnThr: 8.439 ± 2.822
1.406GlnVal: 1.406 ± 1.227
0.0GlnTrp: 0.0 ± 0.0
1.406GlnTyr: 1.406 ± 0.805
0.0GlnXaa: 0.0 ± 0.0
Arg
4.219ArgAla: 4.219 ± 3.68
2.813ArgCys: 2.813 ± 3.711
1.406ArgAsp: 1.406 ± 0.805
4.219ArgGlu: 4.219 ± 3.68
1.406ArgPhe: 1.406 ± 0.805
8.439ArgGly: 8.439 ± 4.065
1.406ArgHis: 1.406 ± 1.227
2.813ArgIle: 2.813 ± 0.941
1.406ArgLys: 1.406 ± 1.227
4.219ArgLeu: 4.219 ± 1.249
2.813ArgMet: 2.813 ± 0.941
1.406ArgAsn: 1.406 ± 1.227
7.032ArgPro: 7.032 ± 4.904
5.626ArgGln: 5.626 ± 4.907
9.845ArgArg: 9.845 ± 6.871
15.471ArgSer: 15.471 ± 9.321
2.813ArgThr: 2.813 ± 3.711
4.219ArgVal: 4.219 ± 2.033
0.0ArgTrp: 0.0 ± 0.0
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
1.406SerAla: 1.406 ± 1.227
2.813SerCys: 2.813 ± 1.486
2.813SerAsp: 2.813 ± 0.941
5.626SerGlu: 5.626 ± 1.88
1.406SerPhe: 1.406 ± 0.805
1.406SerGly: 1.406 ± 0.805
1.406SerHis: 1.406 ± 1.227
8.439SerIle: 8.439 ± 1.359
0.0SerLys: 0.0 ± 0.0
7.032SerLeu: 7.032 ± 4.721
5.626SerMet: 5.626 ± 0.999
8.439SerAsn: 8.439 ± 3.372
4.219SerPro: 4.219 ± 3.264
4.219SerGln: 4.219 ± 1.249
4.219SerArg: 4.219 ± 3.68
5.626SerSer: 5.626 ± 1.905
7.032SerThr: 7.032 ± 2.883
7.032SerVal: 7.032 ± 2.883
0.0SerTrp: 0.0 ± 0.0
1.406SerTyr: 1.406 ± 0.805
0.0SerXaa: 0.0 ± 0.0
Thr
1.406ThrAla: 1.406 ± 0.805
1.406ThrCys: 1.406 ± 1.856
1.406ThrAsp: 1.406 ± 0.805
4.219ThrGlu: 4.219 ± 1.256
0.0ThrPhe: 0.0 ± 0.0
4.219ThrGly: 4.219 ± 1.507
1.406ThrHis: 1.406 ± 1.227
1.406ThrIle: 1.406 ± 1.227
5.626ThrLys: 5.626 ± 3.026
8.439ThrLeu: 8.439 ± 0.55
0.0ThrMet: 0.0 ± 0.0
9.845ThrAsn: 9.845 ± 3.935
2.813ThrPro: 2.813 ± 1.61
4.219ThrGln: 4.219 ± 2.415
5.626ThrArg: 5.626 ± 4.04
4.219ThrSer: 4.219 ± 1.507
1.406ThrThr: 1.406 ± 1.856
5.626ThrVal: 5.626 ± 0.609
1.406ThrTrp: 1.406 ± 0.805
2.813ThrTyr: 2.813 ± 1.61
0.0ThrXaa: 0.0 ± 0.0
Val
4.219ValAla: 4.219 ± 2.415
1.406ValCys: 1.406 ± 1.227
7.032ValAsp: 7.032 ± 2.608
2.813ValGlu: 2.813 ± 1.61
1.406ValPhe: 1.406 ± 1.856
8.439ValGly: 8.439 ± 2.499
1.406ValHis: 1.406 ± 1.227
0.0ValIle: 0.0 ± 0.0
5.626ValLys: 5.626 ± 3.22
5.626ValLeu: 5.626 ± 4.04
1.406ValMet: 1.406 ± 0.805
2.813ValAsn: 2.813 ± 1.486
5.626ValPro: 5.626 ± 3.026
1.406ValGln: 1.406 ± 1.227
8.439ValArg: 8.439 ± 4.212
5.626ValSer: 5.626 ± 2.972
2.813ValThr: 2.813 ± 1.61
9.845ValVal: 9.845 ± 0.648
2.813ValTrp: 2.813 ± 1.486
1.406ValTyr: 1.406 ± 0.805
0.0ValXaa: 0.0 ± 0.0
Trp
1.406TrpAla: 1.406 ± 1.856
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.406TrpGlu: 1.406 ± 0.805
1.406TrpPhe: 1.406 ± 1.856
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.406TrpLys: 1.406 ± 0.805
4.219TrpLeu: 4.219 ± 5.567
1.406TrpMet: 1.406 ± 1.856
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.813TrpSer: 2.813 ± 1.61
1.406TrpThr: 1.406 ± 0.805
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.406TrpTyr: 1.406 ± 0.805
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.626TyrAla: 5.626 ± 3.22
0.0TyrCys: 0.0 ± 0.0
1.406TyrAsp: 1.406 ± 0.805
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.813TyrGly: 2.813 ± 1.61
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
5.626TyrLys: 5.626 ± 1.88
0.0TyrLeu: 0.0 ± 0.0
1.406TyrMet: 1.406 ± 0.805
0.0TyrAsn: 0.0 ± 0.0
2.813TyrPro: 2.813 ± 1.61
0.0TyrGln: 0.0 ± 0.0
2.813TyrArg: 2.813 ± 1.61
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
1.406TyrVal: 1.406 ± 0.805
0.0TyrTrp: 0.0 ± 0.0
2.813TyrTyr: 2.813 ± 1.61
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (712 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski