Amino acid dipepetide frequency for Apis mellifera associated microvirus 39

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.622AlaAla: 9.622 ± 3.544
0.687AlaCys: 0.687 ± 0.737
2.062AlaAsp: 2.062 ± 0.99
5.498AlaGlu: 5.498 ± 3.141
2.062AlaPhe: 2.062 ± 0.949
7.56AlaGly: 7.56 ± 1.947
0.0AlaHis: 0.0 ± 0.0
2.749AlaIle: 2.749 ± 1.608
4.124AlaLys: 4.124 ± 2.212
10.997AlaLeu: 10.997 ± 2.322
2.062AlaMet: 2.062 ± 1.595
4.124AlaAsn: 4.124 ± 1.906
6.186AlaPro: 6.186 ± 1.749
5.498AlaGln: 5.498 ± 2.44
13.058AlaArg: 13.058 ± 1.427
7.56AlaSer: 7.56 ± 2.106
3.436AlaThr: 3.436 ± 1.115
5.498AlaVal: 5.498 ± 0.868
1.375AlaTrp: 1.375 ± 1.474
0.687AlaTyr: 0.687 ± 0.522
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.375CysAsp: 1.375 ± 0.673
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.687CysGly: 0.687 ± 0.737
0.687CysHis: 0.687 ± 0.737
1.375CysIle: 1.375 ± 1.151
0.0CysLys: 0.0 ± 0.0
0.687CysLeu: 0.687 ± 0.737
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.687CysPro: 0.687 ± 0.832
0.0CysGln: 0.0 ± 0.0
1.375CysArg: 1.375 ± 1.151
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.873AspAla: 6.873 ± 1.457
0.0AspCys: 0.0 ± 0.0
3.436AspAsp: 3.436 ± 2.377
2.749AspGlu: 2.749 ± 0.666
2.062AspPhe: 2.062 ± 1.122
0.687AspGly: 0.687 ± 0.522
0.687AspHis: 0.687 ± 0.747
1.375AspIle: 1.375 ± 0.958
0.0AspLys: 0.0 ± 0.0
4.811AspLeu: 4.811 ± 0.612
0.687AspMet: 0.687 ± 0.522
1.375AspAsn: 1.375 ± 0.653
6.873AspPro: 6.873 ± 1.705
2.062AspGln: 2.062 ± 0.798
2.062AspArg: 2.062 ± 0.955
1.375AspSer: 1.375 ± 1.118
2.749AspThr: 2.749 ± 0.713
2.062AspVal: 2.062 ± 0.564
2.062AspTrp: 2.062 ± 0.79
2.062AspTyr: 2.062 ± 1.566
0.0AspXaa: 0.0 ± 0.0
Glu
3.436GluAla: 3.436 ± 1.115
0.0GluCys: 0.0 ± 0.0
6.873GluAsp: 6.873 ± 1.163
2.749GluGlu: 2.749 ± 1.044
4.811GluPhe: 4.811 ± 1.124
1.375GluGly: 1.375 ± 0.958
2.749GluHis: 2.749 ± 1.595
4.811GluIle: 4.811 ± 0.863
1.375GluLys: 1.375 ± 0.653
5.498GluLeu: 5.498 ± 1.39
0.687GluMet: 0.687 ± 0.747
0.687GluAsn: 0.687 ± 0.737
2.749GluPro: 2.749 ± 1.467
1.375GluGln: 1.375 ± 0.96
2.062GluArg: 2.062 ± 1.454
3.436GluSer: 3.436 ± 1.326
4.124GluThr: 4.124 ± 1.426
4.811GluVal: 4.811 ± 1.444
0.687GluTrp: 0.687 ± 0.647
4.124GluTyr: 4.124 ± 1.19
0.0GluXaa: 0.0 ± 0.0
Phe
4.811PheAla: 4.811 ± 0.896
0.0PheCys: 0.0 ± 0.0
2.062PheAsp: 2.062 ± 1.454
2.062PheGlu: 2.062 ± 1.454
1.375PhePhe: 1.375 ± 0.673
2.749PheGly: 2.749 ± 1.346
0.687PheHis: 0.687 ± 0.647
2.062PheIle: 2.062 ± 0.99
0.0PheLys: 0.0 ± 0.0
1.375PheLeu: 1.375 ± 0.82
0.0PheMet: 0.0 ± 0.475
0.687PheAsn: 0.687 ± 0.851
2.062PhePro: 2.062 ± 0.564
0.687PheGln: 0.687 ± 0.851
4.124PheArg: 4.124 ± 2.086
3.436PheSer: 3.436 ± 1.326
2.749PheThr: 2.749 ± 1.356
3.436PheVal: 3.436 ± 0.591
0.687PheTrp: 0.687 ± 0.522
0.687PheTyr: 0.687 ± 0.522
0.0PheXaa: 0.0 ± 0.0
Gly
7.56GlyAla: 7.56 ± 3.094
0.687GlyCys: 0.687 ± 0.737
5.498GlyAsp: 5.498 ± 1.488
4.124GlyGlu: 4.124 ± 0.499
4.811GlyPhe: 4.811 ± 1.753
7.56GlyGly: 7.56 ± 1.748
2.749GlyHis: 2.749 ± 0.956
4.811GlyIle: 4.811 ± 1.557
4.124GlyLys: 4.124 ± 1.43
2.749GlyLeu: 2.749 ± 1.138
1.375GlyMet: 1.375 ± 0.73
2.749GlyAsn: 2.749 ± 0.713
3.436GlyPro: 3.436 ± 1.326
3.436GlyGln: 3.436 ± 1.421
5.498GlyArg: 5.498 ± 2.321
4.811GlySer: 4.811 ± 1.66
2.749GlyThr: 2.749 ± 0.872
4.124GlyVal: 4.124 ± 1.604
1.375GlyTrp: 1.375 ± 0.653
2.749GlyTyr: 2.749 ± 1.381
0.0GlyXaa: 0.0 ± 0.0
His
2.062HisAla: 2.062 ± 1.736
0.0HisCys: 0.0 ± 0.0
0.687HisAsp: 0.687 ± 0.737
1.375HisGlu: 1.375 ± 1.493
0.687HisPhe: 0.687 ± 0.747
3.436HisGly: 3.436 ± 1.415
1.375HisHis: 1.375 ± 0.939
1.375HisIle: 1.375 ± 0.797
0.0HisLys: 0.0 ± 0.0
2.062HisLeu: 2.062 ± 1.419
0.687HisMet: 0.687 ± 0.522
0.0HisAsn: 0.0 ± 0.0
3.436HisPro: 3.436 ± 1.079
2.062HisGln: 2.062 ± 0.996
2.062HisArg: 2.062 ± 1.233
0.687HisSer: 0.687 ± 0.522
0.687HisThr: 0.687 ± 0.737
0.0HisVal: 0.0 ± 0.0
0.687HisTrp: 0.687 ± 0.522
1.375HisTyr: 1.375 ± 0.673
0.0HisXaa: 0.0 ± 0.0
Ile
2.749IleAla: 2.749 ± 1.226
0.687IleCys: 0.687 ± 0.851
0.0IleAsp: 0.0 ± 0.0
2.062IleGlu: 2.062 ± 1.224
1.375IlePhe: 1.375 ± 1.044
6.186IleGly: 6.186 ± 1.284
1.375IleHis: 1.375 ± 0.653
0.687IleIle: 0.687 ± 0.647
0.687IleLys: 0.687 ± 0.647
1.375IleLeu: 1.375 ± 1.151
0.0IleMet: 0.0 ± 0.0
3.436IleAsn: 3.436 ± 1.06
4.124IlePro: 4.124 ± 1.602
2.062IleGln: 2.062 ± 1.566
2.749IleArg: 2.749 ± 2.031
4.124IleSer: 4.124 ± 1.855
2.062IleThr: 2.062 ± 0.955
0.687IleVal: 0.687 ± 0.647
1.375IleTrp: 1.375 ± 1.044
1.375IleTyr: 1.375 ± 0.673
0.0IleXaa: 0.0 ± 0.0
Lys
4.124LysAla: 4.124 ± 1.661
0.0LysCys: 0.0 ± 0.0
2.749LysAsp: 2.749 ± 1.467
4.124LysGlu: 4.124 ± 0.936
1.375LysPhe: 1.375 ± 0.673
2.062LysGly: 2.062 ± 0.991
1.375LysHis: 1.375 ± 1.151
0.0LysIle: 0.0 ± 0.0
2.749LysLys: 2.749 ± 1.483
2.749LysLeu: 2.749 ± 1.801
0.687LysMet: 0.687 ± 0.737
0.0LysAsn: 0.0 ± 0.0
4.124LysPro: 4.124 ± 1.182
2.062LysGln: 2.062 ± 1.454
4.124LysArg: 4.124 ± 1.535
0.687LysSer: 0.687 ± 0.522
2.749LysThr: 2.749 ± 0.927
1.375LysVal: 1.375 ± 1.293
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.186LeuAla: 6.186 ± 1.684
0.687LeuCys: 0.687 ± 0.737
4.124LeuAsp: 4.124 ± 1.791
6.873LeuGlu: 6.873 ± 2.483
0.687LeuPhe: 0.687 ± 0.737
9.622LeuGly: 9.622 ± 1.826
1.375LeuHis: 1.375 ± 1.118
1.375LeuIle: 1.375 ± 1.044
2.062LeuLys: 2.062 ± 1.159
4.124LeuLeu: 4.124 ± 1.661
1.375LeuMet: 1.375 ± 0.598
3.436LeuAsn: 3.436 ± 1.95
2.749LeuPro: 2.749 ± 0.927
6.873LeuGln: 6.873 ± 1.944
8.247LeuArg: 8.247 ± 2.833
6.873LeuSer: 6.873 ± 1.759
2.749LeuThr: 2.749 ± 1.346
4.124LeuVal: 4.124 ± 1.748
2.062LeuTrp: 2.062 ± 0.564
0.687LeuTyr: 0.687 ± 0.647
0.0LeuXaa: 0.0 ± 0.0
Met
2.749MetAla: 2.749 ± 1.391
0.687MetCys: 0.687 ± 0.832
0.0MetAsp: 0.0 ± 0.0
0.687MetGlu: 0.687 ± 0.737
0.0MetPhe: 0.0 ± 0.0
2.062MetGly: 2.062 ± 1.311
0.687MetHis: 0.687 ± 0.522
0.0MetIle: 0.0 ± 0.0
0.687MetLys: 0.687 ± 0.522
0.687MetLeu: 0.687 ± 0.747
0.687MetMet: 0.687 ± 0.773
0.0MetAsn: 0.0 ± 0.0
0.687MetPro: 0.687 ± 0.522
1.375MetGln: 1.375 ± 0.958
2.062MetArg: 2.062 ± 2.496
2.749MetSer: 2.749 ± 0.927
1.375MetThr: 1.375 ± 0.673
0.687MetVal: 0.687 ± 0.647
0.0MetTrp: 0.0 ± 0.0
1.375MetTyr: 1.375 ± 0.673
0.0MetXaa: 0.0 ± 0.0
Asn
4.811AsnAla: 4.811 ± 1.66
0.0AsnCys: 0.0 ± 0.0
1.375AsnAsp: 1.375 ± 1.044
2.749AsnGlu: 2.749 ± 1.044
0.0AsnPhe: 0.0 ± 0.0
2.062AsnGly: 2.062 ± 1.271
0.687AsnHis: 0.687 ± 0.522
1.375AsnIle: 1.375 ± 0.673
0.687AsnLys: 0.687 ± 0.522
1.375AsnLeu: 1.375 ± 1.474
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.375AsnPro: 1.375 ± 0.673
4.811AsnGln: 4.811 ± 1.03
3.436AsnArg: 3.436 ± 1.06
0.0AsnSer: 0.0 ± 0.0
1.375AsnThr: 1.375 ± 0.762
2.062AsnVal: 2.062 ± 0.953
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.873ProAla: 6.873 ± 3.828
0.687ProCys: 0.687 ± 0.737
3.436ProAsp: 3.436 ± 1.311
5.498ProGlu: 5.498 ± 0.712
3.436ProPhe: 3.436 ± 1.202
6.186ProGly: 6.186 ± 1.167
3.436ProHis: 3.436 ± 1.833
1.375ProIle: 1.375 ± 1.044
2.749ProLys: 2.749 ± 0.947
4.811ProLeu: 4.811 ± 1.242
2.062ProMet: 2.062 ± 1.143
0.687ProAsn: 0.687 ± 0.851
6.186ProPro: 6.186 ± 2.272
2.749ProGln: 2.749 ± 1.306
8.935ProArg: 8.935 ± 4.08
4.124ProSer: 4.124 ± 2.668
4.811ProThr: 4.811 ± 1.592
4.811ProVal: 4.811 ± 2.069
0.0ProTrp: 0.0 ± 0.0
2.062ProTyr: 2.062 ± 1.122
0.0ProXaa: 0.0 ± 0.0
Gln
7.56GlnAla: 7.56 ± 1.882
0.0GlnCys: 0.0 ± 0.0
1.375GlnAsp: 1.375 ± 1.044
2.749GlnGlu: 2.749 ± 1.29
1.375GlnPhe: 1.375 ± 0.653
3.436GlnGly: 3.436 ± 1.421
0.687GlnHis: 0.687 ± 0.647
2.062GlnIle: 2.062 ± 1.475
2.062GlnLys: 2.062 ± 0.564
5.498GlnLeu: 5.498 ± 1.841
1.375GlnMet: 1.375 ± 0.82
2.749GlnAsn: 2.749 ± 1.29
4.811GlnPro: 4.811 ± 2.322
3.436GlnGln: 3.436 ± 1.593
6.186GlnArg: 6.186 ± 1.872
0.0GlnSer: 0.0 ± 0.0
4.811GlnThr: 4.811 ± 1.559
2.062GlnVal: 2.062 ± 1.554
0.0GlnTrp: 0.0 ± 0.0
0.687GlnTyr: 0.687 ± 0.737
0.0GlnXaa: 0.0 ± 0.0
Arg
4.811ArgAla: 4.811 ± 1.205
0.687ArgCys: 0.687 ± 0.737
3.436ArgAsp: 3.436 ± 1.456
4.811ArgGlu: 4.811 ± 1.124
2.749ArgPhe: 2.749 ± 1.623
2.749ArgGly: 2.749 ± 1.706
2.749ArgHis: 2.749 ± 2.215
6.186ArgIle: 6.186 ± 1.901
4.811ArgLys: 4.811 ± 1.805
6.873ArgLeu: 6.873 ± 1.49
3.436ArgMet: 3.436 ± 2.343
2.749ArgAsn: 2.749 ± 1.207
7.56ArgPro: 7.56 ± 2.784
2.749ArgGln: 2.749 ± 0.947
17.182ArgArg: 17.182 ± 8.032
10.309ArgSer: 10.309 ± 4.27
7.56ArgThr: 7.56 ± 2.387
4.124ArgVal: 4.124 ± 1.664
0.687ArgTrp: 0.687 ± 0.647
6.186ArgTyr: 6.186 ± 2.692
0.0ArgXaa: 0.0 ± 0.0
Ser
5.498SerAla: 5.498 ± 2.763
0.687SerCys: 0.687 ± 0.522
4.811SerAsp: 4.811 ± 1.273
2.749SerGlu: 2.749 ± 1.306
4.124SerPhe: 4.124 ± 0.727
6.186SerGly: 6.186 ± 1.964
0.687SerHis: 0.687 ± 0.522
2.749SerIle: 2.749 ± 1.441
2.062SerLys: 2.062 ± 0.79
6.186SerLeu: 6.186 ± 1.357
0.687SerMet: 0.687 ± 0.747
1.375SerAsn: 1.375 ± 1.044
3.436SerPro: 3.436 ± 1.311
2.062SerGln: 2.062 ± 1.468
4.811SerArg: 4.811 ± 2.694
4.811SerSer: 4.811 ± 0.855
2.062SerThr: 2.062 ± 1.048
6.186SerVal: 6.186 ± 1.591
2.062SerTrp: 2.062 ± 1.94
2.062SerTyr: 2.062 ± 0.906
0.0SerXaa: 0.0 ± 0.0
Thr
6.873ThrAla: 6.873 ± 3.178
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
2.749ThrGlu: 2.749 ± 1.558
2.749ThrPhe: 2.749 ± 1.306
5.498ThrGly: 5.498 ± 1.546
0.687ThrHis: 0.687 ± 0.747
2.749ThrIle: 2.749 ± 1.389
3.436ThrLys: 3.436 ± 1.412
3.436ThrLeu: 3.436 ± 1.456
1.375ThrMet: 1.375 ± 1.044
2.749ThrAsn: 2.749 ± 2.088
6.186ThrPro: 6.186 ± 3.2
5.498ThrGln: 5.498 ± 2.143
1.375ThrArg: 1.375 ± 1.037
2.062ThrSer: 2.062 ± 0.991
6.186ThrThr: 6.186 ± 2.462
1.375ThrVal: 1.375 ± 0.673
1.375ThrTrp: 1.375 ± 1.151
2.749ThrTyr: 2.749 ± 0.713
0.0ThrXaa: 0.0 ± 0.0
Val
2.749ValAla: 2.749 ± 0.986
1.375ValCys: 1.375 ± 1.151
0.687ValAsp: 0.687 ± 0.522
0.0ValGlu: 0.0 ± 0.0
0.687ValPhe: 0.687 ± 0.522
4.124ValGly: 4.124 ± 0.936
0.0ValHis: 0.0 ± 0.0
2.062ValIle: 2.062 ± 0.79
4.124ValLys: 4.124 ± 1.127
5.498ValLeu: 5.498 ± 0.85
1.375ValMet: 1.375 ± 1.044
0.687ValAsn: 0.687 ± 0.522
6.186ValPro: 6.186 ± 1.614
2.749ValGln: 2.749 ± 1.558
7.56ValArg: 7.56 ± 1.295
5.498ValSer: 5.498 ± 1.998
3.436ValThr: 3.436 ± 1.858
2.749ValVal: 2.749 ± 1.381
1.375ValTrp: 1.375 ± 0.653
1.375ValTyr: 1.375 ± 0.797
0.0ValXaa: 0.0 ± 0.0
Trp
1.375TrpAla: 1.375 ± 0.82
0.0TrpCys: 0.0 ± 0.0
1.375TrpAsp: 1.375 ± 1.293
2.062TrpGlu: 2.062 ± 1.566
1.375TrpPhe: 1.375 ± 0.653
1.375TrpGly: 1.375 ± 0.673
1.375TrpHis: 1.375 ± 0.762
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.687TrpLeu: 0.687 ± 0.737
0.0TrpMet: 0.0 ± 0.0
0.687TrpAsn: 0.687 ± 0.522
0.0TrpPro: 0.0 ± 0.0
0.687TrpGln: 0.687 ± 0.522
1.375TrpArg: 1.375 ± 0.82
1.375TrpSer: 1.375 ± 1.293
1.375TrpThr: 1.375 ± 1.015
1.375TrpVal: 1.375 ± 0.653
0.687TrpTrp: 0.687 ± 0.647
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.124TyrAla: 4.124 ± 1.19
0.0TyrCys: 0.0 ± 0.0
0.687TyrAsp: 0.687 ± 0.522
2.749TyrGlu: 2.749 ± 0.947
0.687TyrPhe: 0.687 ± 0.522
1.375TyrGly: 1.375 ± 0.673
0.687TyrHis: 0.687 ± 0.737
0.0TyrIle: 0.0 ± 0.0
1.375TyrLys: 1.375 ± 0.762
4.811TyrLeu: 4.811 ± 2.315
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.062TyrPro: 2.062 ± 0.798
0.687TyrGln: 0.687 ± 0.522
4.124TyrArg: 4.124 ± 1.469
1.375TyrSer: 1.375 ± 0.653
2.062TyrThr: 2.062 ± 0.953
2.749TyrVal: 2.749 ± 1.381
0.687TyrTrp: 0.687 ± 0.522
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1456 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski