Mastomys natalensis papillomavirus (isolate African multimammate rat) (MnPV)

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Iotapapillomavirus; Iotapapillomavirus 1

Average proteome isoelectric point is 6.81

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q84356|VE1_MNPVA Replication protein E1 OS=Mastomys natalensis papillomavirus (isolate African multimammate rat) OX=654915 GN=E1 PE=3 SV=1
MM1 pKa = 7.73IGPDD5 pKa = 3.27TTRR8 pKa = 11.84CLTGEE13 pKa = 4.27TPDD16 pKa = 3.94SVSLYY21 pKa = 9.25CHH23 pKa = 6.29EE24 pKa = 4.63VLDD27 pKa = 4.21EE28 pKa = 5.19DD29 pKa = 4.24EE30 pKa = 5.22LKK32 pKa = 10.87EE33 pKa = 4.13PTEE36 pKa = 4.04AAPPPEE42 pKa = 4.54QYY44 pKa = 10.07TLYY47 pKa = 10.4QVLIEE52 pKa = 4.64CPEE55 pKa = 4.09CNKK58 pKa = 10.01TIRR61 pKa = 11.84LTCAAQAHH69 pKa = 5.57QIRR72 pKa = 11.84GLEE75 pKa = 3.87HH76 pKa = 7.04LLLDD80 pKa = 4.47GLRR83 pKa = 11.84VICPRR88 pKa = 11.84CNQKK92 pKa = 10.3NGRR95 pKa = 11.84SS96 pKa = 3.52

Molecular weight: 10.75 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P30735|VE6_MNPVA Protein E6 OS=Mastomys natalensis papillomavirus (isolate African multimammate rat) OX=654915 GN=E6 PE=3 SV=2
MM1 pKa = 8.05RR2 pKa = 11.84LQILLRR8 pKa = 11.84GFSSTPQTGFPRR20 pKa = 11.84GDD22 pKa = 3.42PVRR25 pKa = 11.84LHH27 pKa = 6.82GNTTTGLPIPLRR39 pKa = 11.84NSSSNQILLRR49 pKa = 11.84EE50 pKa = 4.23GRR52 pKa = 11.84GDD54 pKa = 3.69YY55 pKa = 10.53PDD57 pKa = 3.53GARR60 pKa = 11.84RR61 pKa = 11.84EE62 pKa = 4.06TRR64 pKa = 11.84RR65 pKa = 11.84YY66 pKa = 8.37YY67 pKa = 10.3QGPTPTPRR75 pKa = 11.84SLSPPIYY82 pKa = 9.83RR83 pKa = 11.84PPPSYY88 pKa = 10.45EE89 pKa = 3.37EE90 pKa = 3.64SRR92 pKa = 11.84RR93 pKa = 11.84RR94 pKa = 11.84RR95 pKa = 11.84KK96 pKa = 9.53LRR98 pKa = 11.84RR99 pKa = 11.84RR100 pKa = 11.84QDD102 pKa = 3.01GRR104 pKa = 11.84VKK106 pKa = 10.87YY107 pKa = 9.06PASPYY112 pKa = 8.08RR113 pKa = 11.84TKK115 pKa = 10.91PPGEE119 pKa = 4.08TSSDD123 pKa = 3.7DD124 pKa = 3.57EE125 pKa = 4.89DD126 pKa = 3.78EE127 pKa = 4.47GRR129 pKa = 11.84GGHH132 pKa = 5.71EE133 pKa = 3.86PRR135 pKa = 11.84PQRR138 pKa = 11.84RR139 pKa = 11.84LPRR142 pKa = 11.84GLRR145 pKa = 11.84DD146 pKa = 3.27RR147 pKa = 11.84GEE149 pKa = 4.09RR150 pKa = 11.84APEE153 pKa = 3.63RR154 pKa = 11.84RR155 pKa = 11.84RR156 pKa = 11.84PPVQEE161 pKa = 4.08GEE163 pKa = 4.05EE164 pKa = 4.18DD165 pKa = 3.49VDD167 pKa = 4.63GVGALLDD174 pKa = 4.04DD175 pKa = 4.61LKK177 pKa = 11.15LYY179 pKa = 10.23QEE181 pKa = 4.64PPGDD185 pKa = 3.74PVEE188 pKa = 5.78DD189 pKa = 3.64SDD191 pKa = 5.49SPGSRR196 pKa = 11.84LTPAPPDD203 pKa = 3.4LSRR206 pKa = 11.84YY207 pKa = 10.24DD208 pKa = 3.61STRR211 pKa = 11.84LQVDD215 pKa = 4.07AEE217 pKa = 4.35SSPPRR222 pKa = 11.84TPRR225 pKa = 11.84PAPTLVAEE233 pKa = 4.61CTPGRR238 pKa = 11.84PSPQTGSGQQALGEE252 pKa = 4.28PPSRR256 pKa = 11.84PSRR259 pKa = 11.84GHH261 pKa = 6.15CRR263 pKa = 11.84DD264 pKa = 3.19PRR266 pKa = 11.84TACLLIIKK274 pKa = 9.99GSSNQVKK281 pKa = 10.18CLRR284 pKa = 11.84FRR286 pKa = 11.84LKK288 pKa = 10.12SWHH291 pKa = 6.87HH292 pKa = 6.06SLFSYY297 pKa = 10.66ISTTWQWVPSVGSNRR312 pKa = 11.84IGRR315 pKa = 11.84SRR317 pKa = 11.84ILVMCEE323 pKa = 4.92DD324 pKa = 4.12SAQMDD329 pKa = 3.63RR330 pKa = 11.84FLCTVKK336 pKa = 10.23IPAGMTVEE344 pKa = 4.22QCSMASVV351 pKa = 3.38

Molecular weight: 39.27 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2777

96

602

396.7

44.38

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.834 ± 0.503

2.269 ± 0.572

5.654 ± 0.142

6.41 ± 0.532

2.953 ± 0.512

7.562 ± 0.674

2.233 ± 0.172

4.105 ± 0.463

3.925 ± 0.624

7.922 ± 0.63

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.125 ± 0.295

3.241 ± 0.677

7.814 ± 1.118

3.673 ± 0.422

8.39 ± 1.337

8.57 ± 0.696

6.914 ± 0.371

5.402 ± 0.378

1.404 ± 0.223

3.601 ± 0.441
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski