Amino acid dipepetide frequency for Pisolithus microcarpus 441

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.955AlaAla: 6.955 ± 0.048	1.397AlaCys: 1.397 ± 0.017	3.903AlaAsp: 3.903 ± 0.032	4.467AlaGlu: 4.467 ± 0.028	3.021AlaPhe: 3.021 ± 0.026	4.688AlaGly: 4.688 ± 0.028	2.137AlaHis: 2.137 ± 0.019	4.038AlaIle: 4.038 ± 0.026	3.501AlaLys: 3.501 ± 0.029	8.035AlaLeu: 8.035 ± 0.047	1.897AlaMet: 1.897 ± 0.017	2.663AlaAsn: 2.663 ± 0.024	4.192AlaPro: 4.192 ± 0.035	3.043AlaGln: 3.043 ± 0.022	4.971AlaArg: 4.971 ± 0.038	6.727AlaSer: 6.727 ± 0.035	4.749AlaThr: 4.749 ± 0.033	5.158AlaVal: 5.158 ± 0.031	1.175AlaTrp: 1.175 ± 0.016	2.111AlaTyr: 2.111 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.194CysAla: 1.194 ± 0.015	0.426CysCys: 0.426 ± 0.01	0.833CysAsp: 0.833 ± 0.012	0.774CysGlu: 0.774 ± 0.011	0.699CysPhe: 0.699 ± 0.011	1.126CysGly: 1.126 ± 0.017	0.595CysHis: 0.595 ± 0.011	0.99CysIle: 0.99 ± 0.012	0.761CysLys: 0.761 ± 0.012	1.689CysLeu: 1.689 ± 0.019	0.448CysMet: 0.448 ± 0.011	0.632CysAsn: 0.632 ± 0.01	1.012CysPro: 1.012 ± 0.016	0.69CysGln: 0.69 ± 0.012	1.096CysArg: 1.096 ± 0.017	1.388CysSer: 1.388 ± 0.017	1.043CysThr: 1.043 ± 0.016	1.06CysVal: 1.06 ± 0.013	0.275CysTrp: 0.275 ± 0.007	0.465CysTyr: 0.465 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.342AspAla: 4.342 ± 0.03	0.795AspCys: 0.795 ± 0.012	4.009AspAsp: 4.009 ± 0.035	4.001AspGlu: 4.001 ± 0.03	2.03AspPhe: 2.03 ± 0.02	3.912AspGly: 3.912 ± 0.032	1.467AspHis: 1.467 ± 0.016	3.157AspIle: 3.157 ± 0.021	2.173AspLys: 2.173 ± 0.018	4.983AspLeu: 4.983 ± 0.032	1.212AspMet: 1.212 ± 0.015	1.792AspAsn: 1.792 ± 0.018	3.252AspPro: 3.252 ± 0.022	1.691AspGln: 1.691 ± 0.017	2.986AspArg: 2.986 ± 0.03	3.992AspSer: 3.992 ± 0.031	3.105AspThr: 3.105 ± 0.021	4.081AspVal: 4.081 ± 0.025	0.928AspTrp: 0.928 ± 0.013	1.523AspTyr: 1.523 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.69GluAla: 4.69 ± 0.033	0.922GluCys: 0.922 ± 0.013	3.907GluAsp: 3.907 ± 0.027	4.949GluGlu: 4.949 ± 0.047	1.85GluPhe: 1.85 ± 0.018	3.707GluGly: 3.707 ± 0.027	1.554GluHis: 1.554 ± 0.016	2.723GluIle: 2.723 ± 0.022	2.855GluLys: 2.855 ± 0.024	5.379GluLeu: 5.379 ± 0.033	1.375GluMet: 1.375 ± 0.018	1.855GluAsn: 1.855 ± 0.016	2.462GluPro: 2.462 ± 0.021	2.217GluGln: 2.217 ± 0.02	4.071GluArg: 4.071 ± 0.033	3.886GluSer: 3.886 ± 0.031	3.014GluThr: 3.014 ± 0.026	3.905GluVal: 3.905 ± 0.027	0.988GluTrp: 0.988 ± 0.013	1.586GluTyr: 1.586 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.773PheAla: 2.773 ± 0.024	0.703PheCys: 0.703 ± 0.012	2.176PheAsp: 2.176 ± 0.024	1.974PheGlu: 1.974 ± 0.02	1.483PhePhe: 1.483 ± 0.016	2.483PheGly: 2.483 ± 0.024	1.21PheHis: 1.21 ± 0.014	1.724PheIle: 1.724 ± 0.017	1.498PheLys: 1.498 ± 0.017	3.493PheLeu: 3.493 ± 0.026	0.817PheMet: 0.817 ± 0.012	1.338PheAsn: 1.338 ± 0.015	2.112PhePro: 2.112 ± 0.02	1.358PheGln: 1.358 ± 0.015	2.062PheArg: 2.062 ± 0.016	3.156PheSer: 3.156 ± 0.022	2.193PheThr: 2.193 ± 0.02	2.43PheVal: 2.43 ± 0.02	0.633PheTrp: 0.633 ± 0.011	1.093PheTyr: 1.093 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.249GlyAla: 4.249 ± 0.032	1.049GlyCys: 1.049 ± 0.015	3.372GlyAsp: 3.372 ± 0.026	3.383GlyGlu: 3.383 ± 0.024	2.264GlyPhe: 2.264 ± 0.024	4.576GlyGly: 4.576 ± 0.043	1.9GlyHis: 1.9 ± 0.022	3.179GlyIle: 3.179 ± 0.022	3.228GlyLys: 3.228 ± 0.029	5.381GlyLeu: 5.381 ± 0.029	1.578GlyMet: 1.578 ± 0.019	2.25GlyAsn: 2.25 ± 0.022	3.029GlyPro: 3.029 ± 0.028	2.246GlyGln: 2.246 ± 0.022	3.983GlyArg: 3.983 ± 0.025	5.378GlySer: 5.378 ± 0.036	3.841GlyThr: 3.841 ± 0.028	4.228GlyVal: 4.228 ± 0.031	1.054GlyTrp: 1.054 ± 0.014	1.797GlyTyr: 1.797 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	2.381HisAla: 2.381 ± 0.021	0.541HisCys: 0.541 ± 0.011	1.541HisAsp: 1.541 ± 0.017	1.458HisGlu: 1.458 ± 0.016	1.15HisPhe: 1.15 ± 0.014	1.848HisGly: 1.848 ± 0.018	1.126HisHis: 1.126 ± 0.015	1.562HisIle: 1.562 ± 0.017	1.078HisLys: 1.078 ± 0.014	2.989HisLeu: 2.989 ± 0.027	0.637HisMet: 0.637 ± 0.01	0.988HisAsn: 0.988 ± 0.016	2.217HisPro: 2.217 ± 0.023	1.077HisGln: 1.077 ± 0.015	1.895HisArg: 1.895 ± 0.019	2.416HisSer: 2.416 ± 0.02	1.781HisThr: 1.781 ± 0.02	1.976HisVal: 1.976 ± 0.019	0.462HisTrp: 0.462 ± 0.01	0.779HisTyr: 0.779 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.838IleAla: 3.838 ± 0.026	0.947IleCys: 0.947 ± 0.015	2.649IleAsp: 2.649 ± 0.022	2.545IleGlu: 2.545 ± 0.023	1.929IlePhe: 1.929 ± 0.019	2.796IleGly: 2.796 ± 0.026	1.529IleHis: 1.529 ± 0.017	2.369IleIle: 2.369 ± 0.023	2.019IleLys: 2.019 ± 0.023	4.655IleLeu: 4.655 ± 0.032	1.031IleMet: 1.031 ± 0.014	1.64IleAsn: 1.64 ± 0.017	3.336IlePro: 3.336 ± 0.02	1.931IleGln: 1.931 ± 0.02	2.943IleArg: 2.943 ± 0.024	3.99IleSer: 3.99 ± 0.025	2.814IleThr: 2.814 ± 0.021	3.249IleVal: 3.249 ± 0.025	0.74IleTrp: 0.74 ± 0.012	1.324IleTyr: 1.324 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.683LysAla: 3.683 ± 0.03	0.716LysCys: 0.716 ± 0.011	2.472LysAsp: 2.472 ± 0.022	2.967LysGlu: 2.967 ± 0.025	1.431LysPhe: 1.431 ± 0.017	2.688LysGly: 2.688 ± 0.027	1.296LysHis: 1.296 ± 0.016	1.981LysIle: 1.981 ± 0.019	2.714LysLys: 2.714 ± 0.034	4.045LysLeu: 4.045 ± 0.029	0.974LysMet: 0.974 ± 0.013	1.46LysAsn: 1.46 ± 0.016	2.352LysPro: 2.352 ± 0.021	1.71LysGln: 1.71 ± 0.019	3.24LysArg: 3.24 ± 0.028	3.172LysSer: 3.172 ± 0.022	2.458LysThr: 2.458 ± 0.022	2.838LysVal: 2.838 ± 0.025	0.674LysTrp: 0.674 ± 0.009	1.326LysTyr: 1.326 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.859LeuAla: 7.859 ± 0.046	1.751LeuCys: 1.751 ± 0.02	5.242LeuAsp: 5.242 ± 0.026	5.656LeuGlu: 5.656 ± 0.039	3.468LeuPhe: 3.468 ± 0.026	5.485LeuGly: 5.485 ± 0.035	3.029LeuHis: 3.029 ± 0.026	3.88LeuIle: 3.88 ± 0.027	4.03LeuLys: 4.03 ± 0.029	8.95LeuLeu: 8.95 ± 0.05	1.945LeuMet: 1.945 ± 0.018	3.014LeuAsn: 3.014 ± 0.022	6.214LeuPro: 6.214 ± 0.037	4.142LeuGln: 4.142 ± 0.027	6.194LeuArg: 6.194 ± 0.035	8.138LeuSer: 8.138 ± 0.04	5.286LeuThr: 5.286 ± 0.029	5.888LeuVal: 5.888 ± 0.038	1.331LeuTrp: 1.331 ± 0.015	2.455LeuTyr: 2.455 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.912MetAla: 1.912 ± 0.017	0.367MetCys: 0.367 ± 0.008	1.371MetAsp: 1.371 ± 0.016	1.408MetGlu: 1.408 ± 0.013	0.786MetPhe: 0.786 ± 0.012	1.237MetGly: 1.237 ± 0.016	0.68MetHis: 0.68 ± 0.009	0.944MetIle: 0.944 ± 0.012	1.062MetLys: 1.062 ± 0.015	1.957MetLeu: 1.957 ± 0.018	0.539MetMet: 0.539 ± 0.01	0.751MetAsn: 0.751 ± 0.013	1.303MetPro: 1.303 ± 0.015	0.971MetGln: 0.971 ± 0.012	1.316MetArg: 1.316 ± 0.016	2.053MetSer: 2.053 ± 0.019	1.379MetThr: 1.379 ± 0.016	1.428MetVal: 1.428 ± 0.015	0.345MetTrp: 0.345 ± 0.008	0.559MetTyr: 0.559 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.849AsnAla: 2.849 ± 0.024	0.552AsnCys: 0.552 ± 0.01	1.834AsnAsp: 1.834 ± 0.019	1.818AsnGlu: 1.818 ± 0.02	1.307AsnPhe: 1.307 ± 0.017	2.34AsnGly: 2.34 ± 0.023	0.974AsnHis: 0.974 ± 0.012	1.911AsnIle: 1.911 ± 0.02	1.394AsnLys: 1.394 ± 0.019	3.171AsnLeu: 3.171 ± 0.023	0.828AsnMet: 0.828 ± 0.013	1.237AsnAsn: 1.237 ± 0.016	2.239AsnPro: 2.239 ± 0.02	1.172AsnGln: 1.172 ± 0.015	1.807AsnArg: 1.807 ± 0.017	2.542AsnSer: 2.542 ± 0.021	2.031AsnThr: 2.031 ± 0.02	2.496AsnVal: 2.496 ± 0.022	0.496AsnTrp: 0.496 ± 0.009	0.91AsnTyr: 0.91 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.601ProAla: 4.601 ± 0.035	0.901ProCys: 0.901 ± 0.014	3.265ProAsp: 3.265 ± 0.025	3.224ProGlu: 3.224 ± 0.024	2.176ProPhe: 2.176 ± 0.02	3.505ProGly: 3.505 ± 0.028	1.805ProHis: 1.805 ± 0.02	2.571ProIle: 2.571 ± 0.019	2.31ProLys: 2.31 ± 0.023	5.374ProLeu: 5.374 ± 0.031	1.14ProMet: 1.14 ± 0.013	2.092ProAsn: 2.092 ± 0.019	5.94ProPro: 5.94 ± 0.058	2.339ProGln: 2.339 ± 0.022	3.623ProArg: 3.623 ± 0.031	7.106ProSer: 7.106 ± 0.05	4.284ProThr: 4.284 ± 0.029	3.891ProVal: 3.891 ± 0.033	0.799ProTrp: 0.799 ± 0.013	1.583ProTyr: 1.583 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.118GlnAla: 3.118 ± 0.022	0.689GlnCys: 0.689 ± 0.012	1.971GlnAsp: 1.971 ± 0.016	2.298GlnGlu: 2.298 ± 0.022	1.217GlnPhe: 1.217 ± 0.016	2.24GlnGly: 2.24 ± 0.021	1.234GlnHis: 1.234 ± 0.014	1.786GlnIle: 1.786 ± 0.019	1.669GlnLys: 1.669 ± 0.017	3.764GlnLeu: 3.764 ± 0.026	0.89GlnMet: 0.89 ± 0.013	1.342GlnAsn: 1.342 ± 0.017	2.435GlnPro: 2.435 ± 0.025	2.054GlnGln: 2.054 ± 0.026	2.583GlnArg: 2.583 ± 0.023	3.042GlnSer: 3.042 ± 0.023	2.153GlnThr: 2.153 ± 0.019	2.469GlnVal: 2.469 ± 0.022	0.677GlnTrp: 0.677 ± 0.011	1.135GlnTyr: 1.135 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.888ArgAla: 4.888 ± 0.029	1.065ArgCys: 1.065 ± 0.015	3.254ArgAsp: 3.254 ± 0.027	3.815ArgGlu: 3.815 ± 0.03	2.241ArgPhe: 2.241 ± 0.019	3.728ArgGly: 3.728 ± 0.029	1.84ArgHis: 1.84 ± 0.018	3.117ArgIle: 3.117 ± 0.024	3.285ArgLys: 3.285 ± 0.03	5.817ArgLeu: 5.817 ± 0.035	1.436ArgMet: 1.436 ± 0.016	2.124ArgAsn: 2.124 ± 0.019	3.504ArgPro: 3.504 ± 0.028	2.455ArgGln: 2.455 ± 0.025	5.155ArgArg: 5.155 ± 0.038	5.228ArgSer: 5.228 ± 0.04	3.661ArgThr: 3.661 ± 0.029	3.969ArgVal: 3.969 ± 0.027	1.049ArgTrp: 1.049 ± 0.015	1.773ArgTyr: 1.773 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.408SerAla: 6.408 ± 0.036	1.338SerCys: 1.338 ± 0.016	4.339SerAsp: 4.339 ± 0.033	4.037SerGlu: 4.037 ± 0.025	3.076SerPhe: 3.076 ± 0.024	5.388SerGly: 5.388 ± 0.038	2.539SerHis: 2.539 ± 0.022	3.999SerIle: 3.999 ± 0.031	3.483SerLys: 3.483 ± 0.023	8.025SerLeu: 8.025 ± 0.042	1.852SerMet: 1.852 ± 0.019	2.867SerAsn: 2.867 ± 0.026	6.071SerPro: 6.071 ± 0.053	3.358SerGln: 3.358 ± 0.024	5.329SerArg: 5.329 ± 0.033	9.568SerSer: 9.568 ± 0.06	5.997SerThr: 5.997 ± 0.035	5.278SerVal: 5.278 ± 0.033	1.114SerTrp: 1.114 ± 0.014	2.041SerTyr: 2.041 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	4.737ThrAla: 4.737 ± 0.03	1.107ThrCys: 1.107 ± 0.014	2.827ThrAsp: 2.827 ± 0.023	2.916ThrGlu: 2.916 ± 0.023	2.35ThrPhe: 2.35 ± 0.02	3.761ThrGly: 3.761 ± 0.028	1.698ThrHis: 1.698 ± 0.02	2.989ThrIle: 2.989 ± 0.026	2.353ThrLys: 2.353 ± 0.019	5.853ThrLeu: 5.853 ± 0.034	1.255ThrMet: 1.255 ± 0.013	1.96ThrAsn: 1.96 ± 0.019	4.363ThrPro: 4.363 ± 0.035	2.096ThrGln: 2.096 ± 0.018	3.613ThrArg: 3.613 ± 0.027	5.825ThrSer: 5.825 ± 0.038	4.27ThrThr: 4.27 ± 0.029	3.873ThrVal: 3.873 ± 0.026	0.867ThrTrp: 0.867 ± 0.012	1.624ThrTyr: 1.624 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.117ValAla: 5.117 ± 0.03	1.123ValCys: 1.123 ± 0.013	3.856ValAsp: 3.856 ± 0.026	3.907ValGlu: 3.907 ± 0.026	2.498ValPhe: 2.498 ± 0.023	3.945ValGly: 3.945 ± 0.028	1.922ValHis: 1.922 ± 0.019	3.225ValIle: 3.225 ± 0.024	2.876ValLys: 2.876 ± 0.024	6.247ValLeu: 6.247 ± 0.035	1.471ValMet: 1.471 ± 0.017	2.227ValAsn: 2.227 ± 0.021	4.213ValPro: 4.213 ± 0.032	2.591ValGln: 2.591 ± 0.023	3.873ValArg: 3.873 ± 0.027	5.265ValSer: 5.265 ± 0.028	3.802ValThr: 3.802 ± 0.028	4.774ValVal: 4.774 ± 0.034	1.004ValTrp: 1.004 ± 0.014	1.759ValTyr: 1.759 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.126TrpAla: 1.126 ± 0.013	0.314TrpCys: 0.314 ± 0.007	0.959TrpAsp: 0.959 ± 0.015	0.891TrpGlu: 0.891 ± 0.013	0.598TrpPhe: 0.598 ± 0.01	0.827TrpGly: 0.827 ± 0.014	0.472TrpHis: 0.472 ± 0.009	0.767TrpIle: 0.767 ± 0.012	0.83TrpLys: 0.83 ± 0.012	1.393TrpLeu: 1.393 ± 0.017	0.433TrpMet: 0.433 ± 0.008	0.645TrpAsn: 0.645 ± 0.011	0.68TrpPro: 0.68 ± 0.01	0.596TrpGln: 0.596 ± 0.011	1.014TrpArg: 1.014 ± 0.013	1.15TrpSer: 1.15 ± 0.015	0.941TrpThr: 0.941 ± 0.012	0.923TrpVal: 0.923 ± 0.013	0.317TrpTrp: 0.317 ± 0.009	0.449TrpTyr: 0.449 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.107TyrAla: 2.107 ± 0.021	0.492TyrCys: 0.492 ± 0.009	1.651TyrAsp: 1.651 ± 0.016	1.408TyrGlu: 1.408 ± 0.014	1.133TyrPhe: 1.133 ± 0.012	1.683TyrGly: 1.683 ± 0.018	0.897TyrHis: 0.897 ± 0.013	1.363TyrIle: 1.363 ± 0.015	1.077TyrLys: 1.077 ± 0.014	2.757TyrLeu: 2.757 ± 0.025	0.612TyrMet: 0.612 ± 0.011	1.029TyrAsn: 1.029 ± 0.014	1.605TyrPro: 1.605 ± 0.016	1.028TyrGln: 1.028 ± 0.013	1.651TyrArg: 1.651 ± 0.016	2.088TyrSer: 2.088 ± 0.021	1.535TyrThr: 1.535 ± 0.015	1.783TyrVal: 1.783 ± 0.017	0.397TyrTrp: 0.397 ± 0.009	0.91TyrTyr: 0.91 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 20748 proteins (5838774 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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