Amino acid dipepetide frequency for Bougainvillea chlorotic vein banding virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.1AlaAla: 1.1 ± 0.563
0.0AlaCys: 0.0 ± 0.0
2.199AlaAsp: 2.199 ± 1.033
6.598AlaGlu: 6.598 ± 1.703
1.466AlaPhe: 1.466 ± 0.751
1.466AlaGly: 1.466 ± 1.086
0.367AlaHis: 0.367 ± 0.188
5.499AlaIle: 5.499 ± 1.95
2.199AlaLys: 2.199 ± 2.318
4.032AlaLeu: 4.032 ± 2.966
1.833AlaMet: 1.833 ± 0.837
1.1AlaAsn: 1.1 ± 0.563
4.399AlaPro: 4.399 ± 1.596
3.666AlaGln: 3.666 ± 0.885
6.965AlaArg: 6.965 ± 2.264
4.765AlaSer: 4.765 ± 1.617
2.199AlaThr: 2.199 ± 1.623
2.933AlaVal: 2.933 ± 1.137
0.367AlaTrp: 0.367 ± 1.176
1.833AlaTyr: 1.833 ± 0.938
0.0AlaXaa: 0.0 ± 0.0
Cys
1.1CysAla: 1.1 ± 0.563
0.733CysCys: 0.733 ± 0.375
1.466CysAsp: 1.466 ± 0.751
0.733CysGlu: 0.733 ± 0.375
0.367CysPhe: 0.367 ± 0.188
0.733CysGly: 0.733 ± 0.375
0.367CysHis: 0.367 ± 0.188
0.733CysIle: 0.733 ± 0.375
2.199CysLys: 2.199 ± 1.126
2.199CysLeu: 2.199 ± 1.08
0.0CysMet: 0.0 ± 0.0
1.466CysAsn: 1.466 ± 0.751
0.367CysPro: 0.367 ± 0.188
1.466CysGln: 1.466 ± 0.751
0.733CysArg: 0.733 ± 1.052
0.367CysSer: 0.367 ± 0.188
1.466CysThr: 1.466 ± 0.875
0.367CysVal: 0.367 ± 0.188
0.0CysTrp: 0.0 ± 0.0
1.1CysTyr: 1.1 ± 0.949
0.0CysXaa: 0.0 ± 0.0
Asp
4.399AspAla: 4.399 ± 1.711
0.367AspCys: 0.367 ± 0.188
3.299AspAsp: 3.299 ± 1.689
2.933AspGlu: 2.933 ± 1.111
2.199AspPhe: 2.199 ± 1.126
2.566AspGly: 2.566 ± 1.314
2.566AspHis: 2.566 ± 1.056
2.199AspIle: 2.199 ± 1.126
3.299AspLys: 3.299 ± 1.304
6.232AspLeu: 6.232 ± 2.766
1.1AspMet: 1.1 ± 0.563
1.466AspAsn: 1.466 ± 0.751
5.132AspPro: 5.132 ± 1.248
2.199AspGln: 2.199 ± 1.126
3.299AspArg: 3.299 ± 1.193
4.032AspSer: 4.032 ± 2.065
5.132AspThr: 5.132 ± 1.248
2.566AspVal: 2.566 ± 2.997
0.367AspTrp: 0.367 ± 1.371
3.299AspTyr: 3.299 ± 1.071
0.0AspXaa: 0.0 ± 0.0
Glu
4.765GluAla: 4.765 ± 1.501
1.466GluCys: 1.466 ± 0.751
5.499GluAsp: 5.499 ± 0.566
10.63GluGlu: 10.63 ± 3.802
2.933GluPhe: 2.933 ± 1.048
4.032GluGly: 4.032 ± 2.923
1.466GluHis: 1.466 ± 1.15
5.499GluIle: 5.499 ± 1.841
5.499GluLys: 5.499 ± 1.319
5.499GluLeu: 5.499 ± 0.566
1.833GluMet: 1.833 ± 0.938
1.833GluAsn: 1.833 ± 0.837
2.199GluPro: 2.199 ± 1.126
3.666GluGln: 3.666 ± 2.351
5.865GluArg: 5.865 ± 1.342
5.132GluSer: 5.132 ± 1.852
4.032GluThr: 4.032 ± 1.418
2.566GluVal: 2.566 ± 1.056
1.466GluTrp: 1.466 ± 0.751
2.566GluTyr: 2.566 ± 1.093
0.0GluXaa: 0.0 ± 0.0
Phe
1.466PheAla: 1.466 ± 1.603
0.367PheCys: 0.367 ± 0.188
2.199PheAsp: 2.199 ± 1.126
2.566PheGlu: 2.566 ± 0.885
0.733PhePhe: 0.733 ± 0.375
0.733PheGly: 0.733 ± 0.375
1.833PheHis: 1.833 ± 0.837
2.199PheIle: 2.199 ± 1.033
2.566PheLys: 2.566 ± 1.501
2.933PheLeu: 2.933 ± 1.111
0.733PheMet: 0.733 ± 0.375
2.933PheAsn: 2.933 ± 0.964
1.833PhePro: 1.833 ± 0.837
3.299PheGln: 3.299 ± 0.952
1.466PheArg: 1.466 ± 1.603
1.833PheSer: 1.833 ± 0.938
4.032PheThr: 4.032 ± 2.065
0.733PheVal: 0.733 ± 0.375
0.0PheTrp: 0.0 ± 0.0
2.566PheTyr: 2.566 ± 2.371
0.0PheXaa: 0.0 ± 0.0
Gly
2.199GlyAla: 2.199 ± 1.126
1.1GlyCys: 1.1 ± 0.563
4.399GlyAsp: 4.399 ± 1.596
3.299GlyGlu: 3.299 ± 1.193
1.466GlyPhe: 1.466 ± 0.751
1.833GlyGly: 1.833 ± 1.043
0.367GlyHis: 0.367 ± 0.188
3.666GlyIle: 3.666 ± 1.877
3.666GlyLys: 3.666 ± 2.086
3.666GlyLeu: 3.666 ± 1.298
1.833GlyMet: 1.833 ± 1.677
1.833GlyAsn: 1.833 ± 1.995
0.733GlyPro: 0.733 ± 1.255
2.566GlyGln: 2.566 ± 0.885
3.299GlyArg: 3.299 ± 3.2
3.666GlySer: 3.666 ± 1.298
3.666GlyThr: 3.666 ± 1.877
2.566GlyVal: 2.566 ± 1.314
0.733GlyTrp: 0.733 ± 0.375
2.199GlyTyr: 2.199 ± 0.841
0.0GlyXaa: 0.0 ± 0.0
His
0.733HisAla: 0.733 ± 0.375
0.367HisCys: 0.367 ± 1.176
0.367HisAsp: 0.367 ± 0.188
1.466HisGlu: 1.466 ± 0.875
2.199HisPhe: 2.199 ± 1.08
1.466HisGly: 1.466 ± 0.751
0.733HisHis: 0.733 ± 1.052
2.933HisIle: 2.933 ± 1.501
0.733HisLys: 0.733 ± 0.375
1.833HisLeu: 1.833 ± 1.448
0.733HisMet: 0.733 ± 0.375
0.367HisAsn: 0.367 ± 0.188
0.733HisPro: 0.733 ± 2.029
2.199HisGln: 2.199 ± 2.934
1.466HisArg: 1.466 ± 2.104
2.199HisSer: 2.199 ± 1.08
2.199HisThr: 2.199 ± 3.745
1.833HisVal: 1.833 ± 0.938
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.833IleAla: 1.833 ± 1.448
2.199IleCys: 2.199 ± 1.126
2.566IleAsp: 2.566 ± 2.239
5.499IleGlu: 5.499 ± 1.161
2.933IlePhe: 2.933 ± 0.964
4.399IleGly: 4.399 ± 2.252
2.566IleHis: 2.566 ± 2.997
4.399IleIle: 4.399 ± 1.681
4.399IleLys: 4.399 ± 4.498
4.399IleLeu: 4.399 ± 0.867
0.733IleMet: 0.733 ± 1.052
3.299IleAsn: 3.299 ± 1.071
2.933IlePro: 2.933 ± 1.137
3.299IleGln: 3.299 ± 1.071
5.499IleArg: 5.499 ± 1.11
2.933IleSer: 2.933 ± 0.964
4.765IleThr: 4.765 ± 0.889
2.199IleVal: 2.199 ± 1.126
0.0IleTrp: 0.0 ± 0.0
1.833IleTyr: 1.833 ± 0.938
0.0IleXaa: 0.0 ± 0.0
Lys
2.933LysAla: 2.933 ± 4.094
1.833LysCys: 1.833 ± 0.938
1.466LysAsp: 1.466 ± 1.086
5.132LysGlu: 5.132 ± 1.834
3.666LysPhe: 3.666 ± 2.086
1.466LysGly: 1.466 ± 0.751
1.466LysHis: 1.466 ± 0.751
5.132LysIle: 5.132 ± 1.852
4.765LysLys: 4.765 ± 1.686
4.399LysLeu: 4.399 ± 3.775
2.199LysMet: 2.199 ± 1.089
4.032LysAsn: 4.032 ± 2.41
6.965LysPro: 6.965 ± 3.566
2.933LysGln: 2.933 ± 2.664
1.1LysArg: 1.1 ± 0.563
2.199LysSer: 2.199 ± 1.126
2.933LysThr: 2.933 ± 1.111
3.666LysVal: 3.666 ± 1.298
0.367LysTrp: 0.367 ± 0.188
2.933LysTyr: 2.933 ± 1.137
0.0LysXaa: 0.0 ± 0.0
Leu
5.865LeuAla: 5.865 ± 3.705
2.199LeuCys: 2.199 ± 1.413
5.865LeuAsp: 5.865 ± 4.599
6.598LeuGlu: 6.598 ± 3.748
2.199LeuPhe: 2.199 ± 2.681
4.032LeuGly: 4.032 ± 2.067
1.1LeuHis: 1.1 ± 1.227
2.199LeuIle: 2.199 ± 3.437
5.865LeuLys: 5.865 ± 2.148
7.331LeuLeu: 7.331 ± 3.47
0.733LeuMet: 0.733 ± 1.052
4.032LeuAsn: 4.032 ± 1.339
6.232LeuPro: 6.232 ± 2.478
6.598LeuGln: 6.598 ± 2.48
4.032LeuArg: 4.032 ± 2.26
7.698LeuSer: 7.698 ± 1.438
1.833LeuThr: 1.833 ± 2.828
4.032LeuVal: 4.032 ± 1.419
0.367LeuTrp: 0.367 ± 0.188
2.199LeuTyr: 2.199 ± 1.033
0.0LeuXaa: 0.0 ± 0.0
Met
1.833MetAla: 1.833 ± 1.1
0.733MetCys: 0.733 ± 0.375
1.466MetAsp: 1.466 ± 0.751
2.566MetGlu: 2.566 ± 1.314
1.466MetPhe: 1.466 ± 1.707
1.466MetGly: 1.466 ± 0.751
0.367MetHis: 0.367 ± 1.176
1.466MetIle: 1.466 ± 0.751
1.466MetLys: 1.466 ± 0.751
1.833MetLeu: 1.833 ± 0.938
0.733MetMet: 0.733 ± 0.375
0.733MetAsn: 0.733 ± 0.375
1.1MetPro: 1.1 ± 0.563
0.367MetGln: 0.367 ± 0.188
1.833MetArg: 1.833 ± 0.837
2.933MetSer: 2.933 ± 1.048
0.733MetThr: 0.733 ± 2.351
1.466MetVal: 1.466 ± 0.751
0.0MetTrp: 0.0 ± 0.0
0.367MetTyr: 0.367 ± 0.188
0.0MetXaa: 0.0 ± 0.0
Asn
1.466AsnAla: 1.466 ± 0.875
0.733AsnCys: 0.733 ± 0.375
4.032AsnAsp: 4.032 ± 1.419
4.032AsnGlu: 4.032 ± 2.065
2.199AsnPhe: 2.199 ± 0.841
3.299AsnGly: 3.299 ± 1.702
0.367AsnHis: 0.367 ± 0.188
3.299AsnIle: 3.299 ± 1.071
1.466AsnLys: 1.466 ± 0.751
4.765AsnLeu: 4.765 ± 3.145
0.367AsnMet: 0.367 ± 0.188
1.1AsnAsn: 1.1 ± 1.159
1.833AsnPro: 1.833 ± 1.1
3.299AsnGln: 3.299 ± 2.071
2.566AsnArg: 2.566 ± 3.593
2.933AsnSer: 2.933 ± 1.394
3.299AsnThr: 3.299 ± 1.689
2.199AsnVal: 2.199 ± 0.841
0.0AsnTrp: 0.0 ± 0.0
1.833AsnTyr: 1.833 ± 0.938
0.0AsnXaa: 0.0 ± 0.0
Pro
3.299ProAla: 3.299 ± 0.952
0.0ProCys: 0.0 ± 0.0
2.933ProAsp: 2.933 ± 1.501
6.232ProGlu: 6.232 ± 1.438
2.566ProPhe: 2.566 ± 1.166
3.666ProGly: 3.666 ± 2.154
1.466ProHis: 1.466 ± 1.086
1.1ProIle: 1.1 ± 1.227
4.765ProLys: 4.765 ± 1.699
4.399ProLeu: 4.399 ± 1.546
0.733ProMet: 0.733 ± 0.912
4.032ProAsn: 4.032 ± 0.965
5.132ProPro: 5.132 ± 2.112
2.933ProGln: 2.933 ± 1.501
2.566ProArg: 2.566 ± 1.972
4.032ProSer: 4.032 ± 1.418
2.933ProThr: 2.933 ± 0.964
2.566ProVal: 2.566 ± 1.093
1.833ProTrp: 1.833 ± 0.938
2.933ProTyr: 2.933 ± 0.964
0.0ProXaa: 0.0 ± 0.0
Gln
3.299GlnAla: 3.299 ± 1.209
1.466GlnCys: 1.466 ± 0.751
2.199GlnAsp: 2.199 ± 1.08
2.566GlnGlu: 2.566 ± 1.314
1.1GlnPhe: 1.1 ± 0.563
2.933GlnGly: 2.933 ± 0.964
2.933GlnHis: 2.933 ± 1.75
2.566GlnIle: 2.566 ± 2.997
2.566GlnLys: 2.566 ± 1.056
6.232GlnLeu: 6.232 ± 4.061
0.367GlnMet: 0.367 ± 0.188
3.666GlnAsn: 3.666 ± 1.422
4.765GlnPro: 4.765 ± 1.863
2.933GlnGln: 2.933 ± 3.774
3.666GlnArg: 3.666 ± 1.304
2.566GlnSer: 2.566 ± 1.093
3.666GlnThr: 3.666 ± 2.199
3.299GlnVal: 3.299 ± 1.689
1.466GlnTrp: 1.466 ± 1.15
1.1GlnTyr: 1.1 ± 0.949
0.0GlnXaa: 0.0 ± 0.0
Arg
3.299ArgAla: 3.299 ± 0.952
0.0ArgCys: 0.0 ± 0.0
4.765ArgAsp: 4.765 ± 1.716
3.666ArgGlu: 3.666 ± 5.123
2.199ArgPhe: 2.199 ± 1.08
4.032ArgGly: 4.032 ± 0.856
1.833ArgHis: 1.833 ± 1.556
3.666ArgIle: 3.666 ± 2.443
2.199ArgLys: 2.199 ± 1.126
4.765ArgLeu: 4.765 ± 1.895
1.833ArgMet: 1.833 ± 0.948
2.199ArgAsn: 2.199 ± 3.155
4.765ArgPro: 4.765 ± 1.649
2.566ArgGln: 2.566 ± 1.816
5.132ArgArg: 5.132 ± 3.632
5.499ArgSer: 5.499 ± 1.841
2.933ArgThr: 2.933 ± 1.137
2.566ArgVal: 2.566 ± 2.539
1.1ArgTrp: 1.1 ± 0.949
1.833ArgTyr: 1.833 ± 0.938
0.0ArgXaa: 0.0 ± 0.0
Ser
2.933SerAla: 2.933 ± 1.111
1.833SerCys: 1.833 ± 0.837
5.865SerAsp: 5.865 ± 2.222
3.666SerGlu: 3.666 ± 1.304
0.733SerPhe: 0.733 ± 0.375
2.933SerGly: 2.933 ± 1.111
1.1SerHis: 1.1 ± 2.223
4.765SerIle: 4.765 ± 1.649
3.666SerLys: 3.666 ± 1.238
5.132SerLeu: 5.132 ± 1.426
4.399SerMet: 4.399 ± 1.546
3.299SerAsn: 3.299 ± 1.07
2.933SerPro: 2.933 ± 2.3
3.666SerGln: 3.666 ± 1.877
5.865SerArg: 5.865 ± 0.438
11.364SerSer: 11.364 ± 3.324
4.765SerThr: 4.765 ± 0.917
2.566SerVal: 2.566 ± 1.314
1.833SerTrp: 1.833 ± 0.938
2.933SerTyr: 2.933 ± 1.501
0.0SerXaa: 0.0 ± 0.0
Thr
4.399ThrAla: 4.399 ± 0.964
0.733ThrCys: 0.733 ± 0.375
3.666ThrAsp: 3.666 ± 1.198
2.933ThrGlu: 2.933 ± 1.048
2.566ThrPhe: 2.566 ± 1.314
3.299ThrGly: 3.299 ± 1.702
1.833ThrHis: 1.833 ± 1.1
4.399ThrIle: 4.399 ± 1.947
2.566ThrLys: 2.566 ± 1.314
4.399ThrLeu: 4.399 ± 2.313
2.199ThrMet: 2.199 ± 1.126
3.299ThrAsn: 3.299 ± 0.952
4.399ThrPro: 4.399 ± 1.554
2.566ThrGln: 2.566 ± 3.873
2.566ThrArg: 2.566 ± 1.816
6.598ThrSer: 6.598 ± 1.36
3.299ThrThr: 3.299 ± 1.193
1.1ThrVal: 1.1 ± 0.563
0.367ThrTrp: 0.367 ± 1.371
1.833ThrTyr: 1.833 ± 1.1
0.0ThrXaa: 0.0 ± 0.0
Val
4.032ValAla: 4.032 ± 1.419
1.466ValCys: 1.466 ± 0.751
3.666ValAsp: 3.666 ± 1.298
2.933ValGlu: 2.933 ± 1.501
1.833ValPhe: 1.833 ± 0.837
1.466ValGly: 1.466 ± 0.751
1.1ValHis: 1.1 ± 0.563
3.666ValIle: 3.666 ± 1.304
4.032ValLys: 4.032 ± 1.418
2.199ValLeu: 2.199 ± 1.126
1.833ValMet: 1.833 ± 0.837
0.733ValAsn: 0.733 ± 0.375
2.566ValPro: 2.566 ± 1.314
2.566ValGln: 2.566 ± 2.796
0.0ValArg: 0.0 ± 0.0
2.933ValSer: 2.933 ± 2.173
2.199ValThr: 2.199 ± 0.841
1.833ValVal: 1.833 ± 0.938
0.0ValTrp: 0.0 ± 0.0
2.199ValTyr: 2.199 ± 0.841
0.0ValXaa: 0.0 ± 0.0
Trp
1.1TrpAla: 1.1 ± 0.949
0.0TrpCys: 0.0 ± 0.0
0.367TrpAsp: 0.367 ± 0.188
1.1TrpGlu: 1.1 ± 0.563
0.367TrpPhe: 0.367 ± 0.188
0.733TrpGly: 0.733 ± 0.375
0.367TrpHis: 0.367 ± 0.188
1.1TrpIle: 1.1 ± 0.949
1.1TrpLys: 1.1 ± 0.563
1.466TrpLeu: 1.466 ± 1.086
0.0TrpMet: 0.0 ± 0.0
0.367TrpAsn: 0.367 ± 0.188
0.367TrpPro: 0.367 ± 1.371
0.733TrpGln: 0.733 ± 1.326
0.733TrpArg: 0.733 ± 0.375
0.367TrpSer: 0.367 ± 0.188
0.367TrpThr: 0.367 ± 0.188
0.367TrpVal: 0.367 ± 0.188
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.933TyrAla: 2.933 ± 1.501
0.367TyrCys: 0.367 ± 0.188
0.367TyrAsp: 0.367 ± 1.443
3.299TyrGlu: 3.299 ± 2.847
1.833TyrPhe: 1.833 ± 0.938
2.566TyrGly: 2.566 ± 0.885
0.367TyrHis: 0.367 ± 0.188
2.199TyrIle: 2.199 ± 1.126
2.566TyrLys: 2.566 ± 1.093
3.299TyrLeu: 3.299 ± 1.07
0.367TyrMet: 0.367 ± 0.188
3.299TyrAsn: 3.299 ± 1.209
0.733TyrPro: 0.733 ± 0.375
1.833TyrGln: 1.833 ± 0.938
2.199TyrArg: 2.199 ± 1.413
2.199TyrSer: 2.199 ± 1.126
2.566TyrThr: 2.566 ± 1.056
1.833TyrVal: 1.833 ± 0.938
0.733TyrTrp: 0.733 ± 0.375
2.933TyrTyr: 2.933 ± 1.75
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski