Amino acid dipepetide frequency for Corynebacterium choanis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.276AlaAla: 19.276 ± 0.332	1.197AlaCys: 1.197 ± 0.046	7.722AlaAsp: 7.722 ± 0.119	6.781AlaGlu: 6.781 ± 0.129	3.13AlaPhe: 3.13 ± 0.071	10.445AlaGly: 10.445 ± 0.125	2.734AlaHis: 2.734 ± 0.062	6.078AlaIle: 6.078 ± 0.097	3.993AlaLys: 3.993 ± 0.085	10.837AlaLeu: 10.837 ± 0.156	2.7AlaMet: 2.7 ± 0.07	3.123AlaAsn: 3.123 ± 0.062	5.86AlaPro: 5.86 ± 0.1	5.035AlaGln: 5.035 ± 0.089	6.28AlaArg: 6.28 ± 0.111	6.136AlaSer: 6.136 ± 0.092	9.327AlaThr: 9.327 ± 0.164	10.086AlaVal: 10.086 ± 0.136	1.243AlaTrp: 1.243 ± 0.041	2.192AlaTyr: 2.192 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.198CysAla: 1.198 ± 0.044	0.307CysCys: 0.307 ± 0.025	0.673CysAsp: 0.673 ± 0.031	0.465CysGlu: 0.465 ± 0.023	0.312CysPhe: 0.312 ± 0.023	1.057CysGly: 1.057 ± 0.034	0.236CysHis: 0.236 ± 0.016	0.379CysIle: 0.379 ± 0.023	0.202CysLys: 0.202 ± 0.017	0.754CysLeu: 0.754 ± 0.031	0.146CysMet: 0.146 ± 0.014	0.245CysAsn: 0.245 ± 0.018	0.57CysPro: 0.57 ± 0.03	0.352CysGln: 0.352 ± 0.02	0.636CysArg: 0.636 ± 0.031	0.688CysSer: 0.688 ± 0.03	0.651CysThr: 0.651 ± 0.032	0.859CysVal: 0.859 ± 0.035	0.177CysTrp: 0.177 ± 0.016	0.23CysTyr: 0.23 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.498AspAla: 6.498 ± 0.102	0.594AspCys: 0.594 ± 0.03	4.104AspAsp: 4.104 ± 0.131	3.993AspGlu: 3.993 ± 0.089	1.836AspPhe: 1.836 ± 0.053	5.162AspGly: 5.162 ± 0.192	1.505AspHis: 1.505 ± 0.051	2.728AspIle: 2.728 ± 0.07	1.742AspLys: 1.742 ± 0.065	4.916AspLeu: 4.916 ± 0.091	1.046AspMet: 1.046 ± 0.035	1.852AspAsn: 1.852 ± 0.063	4.418AspPro: 4.418 ± 0.106	2.137AspGln: 2.137 ± 0.054	3.35AspArg: 3.35 ± 0.082	3.264AspSer: 3.264 ± 0.072	4.05AspThr: 4.05 ± 0.096	4.355AspVal: 4.355 ± 0.093	0.724AspTrp: 0.724 ± 0.033	1.527AspTyr: 1.527 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.463GluAla: 5.463 ± 0.111	0.379GluCys: 0.379 ± 0.022	2.685GluAsp: 2.685 ± 0.072	2.979GluGlu: 2.979 ± 0.09	1.71GluPhe: 1.71 ± 0.055	2.997GluGly: 2.997 ± 0.071	1.588GluHis: 1.588 ± 0.049	2.84GluIle: 2.84 ± 0.066	1.786GluLys: 1.786 ± 0.06	5.597GluLeu: 5.597 ± 0.103	1.049GluMet: 1.049 ± 0.044	1.444GluAsn: 1.444 ± 0.05	2.542GluPro: 2.542 ± 0.071	3.356GluGln: 3.356 ± 0.072	2.85GluArg: 2.85 ± 0.069	2.591GluSer: 2.591 ± 0.056	3.288GluThr: 3.288 ± 0.067	4.16GluVal: 4.16 ± 0.094	0.465GluTrp: 0.465 ± 0.025	1.23GluTyr: 1.23 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	4.276PheAla: 4.276 ± 0.079	0.318PheCys: 0.318 ± 0.02	2.232PheAsp: 2.232 ± 0.061	1.217PheGlu: 1.217 ± 0.046	1.14PhePhe: 1.14 ± 0.044	3.046PheGly: 3.046 ± 0.075	0.81PheHis: 0.81 ± 0.038	1.477PheIle: 1.477 ± 0.052	0.534PheLys: 0.534 ± 0.026	2.398PheLeu: 2.398 ± 0.077	0.484PheMet: 0.484 ± 0.026	0.823PheAsn: 0.823 ± 0.032	1.583PhePro: 1.583 ± 0.046	0.909PheGln: 0.909 ± 0.036	1.498PheArg: 1.498 ± 0.043	1.965PheSer: 1.965 ± 0.047	2.601PheThr: 2.601 ± 0.066	2.508PheVal: 2.508 ± 0.067	0.351PheTrp: 0.351 ± 0.022	0.716PheTyr: 0.716 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	7.97GlyAla: 7.97 ± 0.119	1.026GlyCys: 1.026 ± 0.038	4.873GlyAsp: 4.873 ± 0.119	4.601GlyGlu: 4.601 ± 0.084	2.916GlyPhe: 2.916 ± 0.068	6.198GlyGly: 6.198 ± 0.11	1.8GlyHis: 1.8 ± 0.046	4.434GlyIle: 4.434 ± 0.081	3.195GlyLys: 3.195 ± 0.072	7.22GlyLeu: 7.22 ± 0.119	1.99GlyMet: 1.99 ± 0.055	2.474GlyAsn: 2.474 ± 0.061	2.65GlyPro: 2.65 ± 0.055	3.156GlyGln: 3.156 ± 0.064	4.566GlyArg: 4.566 ± 0.093	4.918GlySer: 4.918 ± 0.083	4.96GlyThr: 4.96 ± 0.098	6.736GlyVal: 6.736 ± 0.108	1.221GlyTrp: 1.221 ± 0.043	1.988GlyTyr: 1.988 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.369HisAla: 2.369 ± 0.055	0.318HisCys: 0.318 ± 0.021	1.477HisAsp: 1.477 ± 0.048	1.061HisGlu: 1.061 ± 0.044	0.683HisPhe: 0.683 ± 0.028	2.012HisGly: 2.012 ± 0.057	0.927HisHis: 0.927 ± 0.041	1.122HisIle: 1.122 ± 0.037	0.515HisLys: 0.515 ± 0.027	2.129HisLeu: 2.129 ± 0.062	0.473HisMet: 0.473 ± 0.027	0.777HisAsn: 0.777 ± 0.036	1.998HisPro: 1.998 ± 0.06	1.058HisGln: 1.058 ± 0.036	1.8HisArg: 1.8 ± 0.055	1.362HisSer: 1.362 ± 0.045	1.868HisThr: 1.868 ± 0.054	1.573HisVal: 1.573 ± 0.043	0.329HisTrp: 0.329 ± 0.024	0.636HisTyr: 0.636 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	7.294IleAla: 7.294 ± 0.117	0.455IleCys: 0.455 ± 0.023	3.921IleAsp: 3.921 ± 0.081	2.452IleGlu: 2.452 ± 0.063	1.375IlePhe: 1.375 ± 0.05	4.423IleGly: 4.423 ± 0.089	1.034IleHis: 1.034 ± 0.043	2.562IleIle: 2.562 ± 0.069	1.079IleLys: 1.079 ± 0.043	3.331IleLeu: 3.331 ± 0.084	0.786IleMet: 0.786 ± 0.036	1.434IleAsn: 1.434 ± 0.049	2.916IlePro: 2.916 ± 0.052	1.161IleGln: 1.161 ± 0.039	2.603IleArg: 2.603 ± 0.055	2.63IleSer: 2.63 ± 0.064	4.172IleThr: 4.172 ± 0.089	4.692IleVal: 4.692 ± 0.097	0.402IleTrp: 0.402 ± 0.024	0.978IleTyr: 0.978 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.225LysAla: 3.225 ± 0.1	0.144LysCys: 0.144 ± 0.014	1.665LysAsp: 1.665 ± 0.076	1.51LysGlu: 1.51 ± 0.053	0.808LysPhe: 0.808 ± 0.035	1.724LysGly: 1.724 ± 0.056	0.678LysHis: 0.678 ± 0.028	1.528LysIle: 1.528 ± 0.056	1.334LysLys: 1.334 ± 0.058	2.861LysLeu: 2.861 ± 0.068	0.634LysMet: 0.634 ± 0.029	0.854LysAsn: 0.854 ± 0.038	1.905LysPro: 1.905 ± 0.06	1.685LysGln: 1.685 ± 0.046	1.765LysArg: 1.765 ± 0.056	1.447LysSer: 1.447 ± 0.045	1.976LysThr: 1.976 ± 0.059	2.184LysVal: 2.184 ± 0.068	0.321LysTrp: 0.321 ± 0.025	0.609LysTyr: 0.609 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.596LeuAla: 12.596 ± 0.171	0.941LeuCys: 0.941 ± 0.042	5.174LeuAsp: 5.174 ± 0.098	3.894LeuGlu: 3.894 ± 0.083	2.759LeuPhe: 2.759 ± 0.074	7.204LeuGly: 7.204 ± 0.127	2.32LeuHis: 2.32 ± 0.056	4.4LeuIle: 4.4 ± 0.108	2.111LeuLys: 2.111 ± 0.054	9.962LeuLeu: 9.962 ± 0.184	1.579LeuMet: 1.579 ± 0.051	2.124LeuAsn: 2.124 ± 0.054	5.86LeuPro: 5.86 ± 0.099	3.77LeuGln: 3.77 ± 0.072	5.706LeuArg: 5.706 ± 0.096	5.35LeuSer: 5.35 ± 0.086	6.222LeuThr: 6.222 ± 0.088	7.882LeuVal: 7.882 ± 0.122	1.154LeuTrp: 1.154 ± 0.049	1.749LeuTyr: 1.749 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.312MetAla: 2.312 ± 0.061	0.213MetCys: 0.213 ± 0.017	0.846MetAsp: 0.846 ± 0.029	0.921MetGlu: 0.921 ± 0.035	0.666MetPhe: 0.666 ± 0.03	1.343MetGly: 1.343 ± 0.051	0.502MetHis: 0.502 ± 0.031	1.112MetIle: 1.112 ± 0.038	0.63MetLys: 0.63 ± 0.029	2.279MetLeu: 2.279 ± 0.062	0.483MetMet: 0.483 ± 0.025	0.588MetAsn: 0.588 ± 0.027	1.139MetPro: 1.139 ± 0.044	0.769MetGln: 0.769 ± 0.036	1.261MetArg: 1.261 ± 0.043	1.32MetSer: 1.32 ± 0.04	1.523MetThr: 1.523 ± 0.048	1.832MetVal: 1.832 ± 0.05	0.244MetTrp: 0.244 ± 0.018	0.353MetTyr: 0.353 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.814AsnAla: 2.814 ± 0.065	0.266AsnCys: 0.266 ± 0.019	1.572AsnAsp: 1.572 ± 0.061	1.421AsnGlu: 1.421 ± 0.046	0.851AsnPhe: 0.851 ± 0.033	2.011AsnGly: 2.011 ± 0.065	0.675AsnHis: 0.675 ± 0.028	1.299AsnIle: 1.299 ± 0.043	0.874AsnLys: 0.874 ± 0.038	2.392AsnLeu: 2.392 ± 0.062	0.523AsnMet: 0.523 ± 0.026	1.122AsnAsn: 1.122 ± 0.05	2.434AsnPro: 2.434 ± 0.052	1.081AsnGln: 1.081 ± 0.043	1.599AsnArg: 1.599 ± 0.048	1.565AsnSer: 1.565 ± 0.052	2.253AsnThr: 2.253 ± 0.097	1.893AsnVal: 1.893 ± 0.048	0.365AsnTrp: 0.365 ± 0.022	0.657AsnTyr: 0.657 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	8.126ProAla: 8.126 ± 0.146	0.392ProCys: 0.392 ± 0.023	3.328ProAsp: 3.328 ± 0.088	3.356ProGlu: 3.356 ± 0.078	1.515ProPhe: 1.515 ± 0.047	4.85ProGly: 4.85 ± 0.09	1.469ProHis: 1.469 ± 0.053	2.338ProIle: 2.338 ± 0.058	1.572ProLys: 1.572 ± 0.056	5.036ProLeu: 5.036 ± 0.087	1.084ProMet: 1.084 ± 0.036	1.473ProAsn: 1.473 ± 0.051	2.936ProPro: 2.936 ± 0.086	2.889ProGln: 2.889 ± 0.063	2.763ProArg: 2.763 ± 0.062	3.043ProSer: 3.043 ± 0.067	4.154ProThr: 4.154 ± 0.09	5.207ProVal: 5.207 ± 0.099	0.743ProTrp: 0.743 ± 0.028	1.15ProTyr: 1.15 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	5.547GlnAla: 5.547 ± 0.096	0.313GlnCys: 0.313 ± 0.021	1.626GlnAsp: 1.626 ± 0.053	1.872GlnGlu: 1.872 ± 0.052	1.174GlnPhe: 1.174 ± 0.034	2.622GlnGly: 2.622 ± 0.051	1.302GlnHis: 1.302 ± 0.046	1.773GlnIle: 1.773 ± 0.047	0.754GlnLys: 0.754 ± 0.031	4.877GlnLeu: 4.877 ± 0.098	0.814GlnMet: 0.814 ± 0.035	0.698GlnAsn: 0.698 ± 0.032	3.141GlnPro: 3.141 ± 0.087	3.268GlnGln: 3.268 ± 0.087	3.233GlnArg: 3.233 ± 0.081	2.102GlnSer: 2.102 ± 0.057	2.042GlnThr: 2.042 ± 0.06	3.324GlnVal: 3.324 ± 0.078	0.719GlnTrp: 0.719 ± 0.028	0.809GlnTyr: 0.809 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.548ArgAla: 5.548 ± 0.104	0.647ArgCys: 0.647 ± 0.029	3.216ArgAsp: 3.216 ± 0.082	3.195ArgGlu: 3.195 ± 0.076	2.066ArgPhe: 2.066 ± 0.056	4.077ArgGly: 4.077 ± 0.085	1.435ArgHis: 1.435 ± 0.041	3.313ArgIle: 3.313 ± 0.08	1.959ArgLys: 1.959 ± 0.056	5.675ArgLeu: 5.675 ± 0.111	1.462ArgMet: 1.462 ± 0.047	1.773ArgAsn: 1.773 ± 0.049	3.017ArgPro: 3.017 ± 0.069	2.781ArgGln: 2.781 ± 0.068	4.961ArgArg: 4.961 ± 0.115	3.195ArgSer: 3.195 ± 0.072	3.322ArgThr: 3.322 ± 0.07	3.826ArgVal: 3.826 ± 0.072	0.932ArgTrp: 0.932 ± 0.037	1.663ArgTyr: 1.663 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.516SerAla: 6.516 ± 0.11	0.566SerCys: 0.566 ± 0.027	3.174SerAsp: 3.174 ± 0.071	2.303SerGlu: 2.303 ± 0.064	1.9SerPhe: 1.9 ± 0.048	4.773SerGly: 4.773 ± 0.082	1.257SerHis: 1.257 ± 0.044	2.544SerIle: 2.544 ± 0.066	1.597SerLys: 1.597 ± 0.055	5.162SerLeu: 5.162 ± 0.085	1.321SerMet: 1.321 ± 0.042	1.696SerAsn: 1.696 ± 0.049	3.363SerPro: 3.363 ± 0.065	2.179SerGln: 2.179 ± 0.061	3.367SerArg: 3.367 ± 0.071	3.966SerSer: 3.966 ± 0.088	4.105SerThr: 4.105 ± 0.079	4.043SerVal: 4.043 ± 0.078	0.945SerTrp: 0.945 ± 0.041	1.272SerTyr: 1.272 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	8.985ThrAla: 8.985 ± 0.171	0.63ThrCys: 0.63 ± 0.04	4.136ThrAsp: 4.136 ± 0.1	2.712ThrGlu: 2.712 ± 0.066	2.038ThrPhe: 2.038 ± 0.048	6.175ThrGly: 6.175 ± 0.091	1.55ThrHis: 1.55 ± 0.045	3.879ThrIle: 3.879 ± 0.096	1.862ThrLys: 1.862 ± 0.063	6.194ThrLeu: 6.194 ± 0.104	1.424ThrMet: 1.424 ± 0.045	2.009ThrAsn: 2.009 ± 0.068	5.072ThrPro: 5.072 ± 0.098	2.217ThrGln: 2.217 ± 0.06	3.263ThrArg: 3.263 ± 0.071	3.929ThrSer: 3.929 ± 0.071	5.766ThrThr: 5.766 ± 0.137	6.921ThrVal: 6.921 ± 0.159	0.838ThrTrp: 0.838 ± 0.032	1.474ThrTyr: 1.474 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	10.769ValAla: 10.769 ± 0.138	0.927ValCys: 0.927 ± 0.033	5.526ValAsp: 5.526 ± 0.106	4.473ValGlu: 4.473 ± 0.102	2.671ValPhe: 2.671 ± 0.062	6.094ValGly: 6.094 ± 0.112	1.858ValHis: 1.858 ± 0.049	4.373ValIle: 4.373 ± 0.074	2.264ValLys: 2.264 ± 0.073	7.534ValLeu: 7.534 ± 0.117	1.631ValMet: 1.631 ± 0.057	2.216ValAsn: 2.216 ± 0.07	4.014ValPro: 4.014 ± 0.082	2.481ValGln: 2.481 ± 0.069	4.041ValArg: 4.041 ± 0.069	4.613ValSer: 4.613 ± 0.092	6.744ValThr: 6.744 ± 0.19	7.733ValVal: 7.733 ± 0.135	0.95ValTrp: 0.95 ± 0.036	1.474ValTyr: 1.474 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	1.181TrpAla: 1.181 ± 0.039	0.195TrpCys: 0.195 ± 0.016	0.585TrpAsp: 0.585 ± 0.027	0.616TrpGlu: 0.616 ± 0.03	0.523TrpPhe: 0.523 ± 0.027	0.835TrpGly: 0.835 ± 0.04	0.288TrpHis: 0.288 ± 0.017	0.674TrpIle: 0.674 ± 0.03	0.37TrpLys: 0.37 ± 0.024	1.559TrpLeu: 1.559 ± 0.053	0.383TrpMet: 0.383 ± 0.022	0.366TrpAsn: 0.366 ± 0.021	0.606TrpPro: 0.606 ± 0.032	0.754TrpGln: 0.754 ± 0.037	0.964TrpArg: 0.964 ± 0.038	0.678TrpSer: 0.678 ± 0.03	0.625TrpThr: 0.625 ± 0.026	0.945TrpVal: 0.945 ± 0.037	0.367TrpTrp: 0.367 ± 0.026	0.275TrpTyr: 0.275 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.208TyrAla: 2.208 ± 0.052	0.307TyrCys: 0.307 ± 0.022	1.267TyrAsp: 1.267 ± 0.041	1.179TyrGlu: 1.179 ± 0.045	0.813TyrPhe: 0.813 ± 0.035	1.844TyrGly: 1.844 ± 0.051	0.517TyrHis: 0.517 ± 0.026	0.845TyrIle: 0.845 ± 0.035	0.485TyrLys: 0.485 ± 0.027	2.048TyrLeu: 2.048 ± 0.055	0.324TyrMet: 0.324 ± 0.02	0.577TyrAsn: 0.577 ± 0.029	1.398TyrPro: 1.398 ± 0.044	0.972TyrGln: 0.972 ± 0.034	1.559TyrArg: 1.559 ± 0.046	1.288TyrSer: 1.288 ± 0.041	1.425TyrThr: 1.425 ± 0.057	1.628TyrVal: 1.628 ± 0.047	0.298TyrTrp: 0.298 ± 0.02	0.528TyrTyr: 0.528 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2308 proteins (778825 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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