Amino acid dipepetide frequency for Medicago sativa alphapartitivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.152AlaAla: 11.152 ± 9.179
0.929AlaCys: 0.929 ± 0.765
5.576AlaAsp: 5.576 ± 4.589
8.364AlaGlu: 8.364 ± 2.667
3.717AlaPhe: 3.717 ± 1.654
2.788AlaGly: 2.788 ± 0.889
1.859AlaHis: 1.859 ± 1.282
1.859AlaIle: 1.859 ± 0.124
3.717AlaLys: 3.717 ± 0.248
3.717AlaLeu: 3.717 ± 1.654
2.788AlaMet: 2.788 ± 0.889
5.576AlaAsn: 5.576 ± 1.778
8.364AlaPro: 8.364 ± 4.073
1.859AlaGln: 1.859 ± 1.53
5.576AlaArg: 5.576 ± 0.372
5.576AlaSer: 5.576 ± 3.184
4.647AlaThr: 4.647 ± 0.393
0.0AlaVal: 0.0 ± 0.0
0.929AlaTrp: 0.929 ± 0.765
0.929AlaTyr: 0.929 ± 0.641
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.929CysCys: 0.929 ± 0.765
0.0CysAsp: 0.0 ± 0.0
1.859CysGlu: 1.859 ± 0.124
0.0CysPhe: 0.0 ± 0.0
0.929CysGly: 0.929 ± 0.641
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.859CysLeu: 1.859 ± 1.53
0.929CysMet: 0.929 ± 0.765
0.0CysAsn: 0.0 ± 0.0
1.859CysPro: 1.859 ± 1.53
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.859CysSer: 1.859 ± 1.53
0.0CysThr: 0.0 ± 0.0
0.929CysVal: 0.929 ± 0.641
0.0CysTrp: 0.0 ± 0.0
0.929CysTyr: 0.929 ± 0.641
0.0CysXaa: 0.0 ± 0.0
Asp
5.576AspAla: 5.576 ± 1.778
0.929AspCys: 0.929 ± 0.765
2.788AspAsp: 2.788 ± 0.889
2.788AspGlu: 2.788 ± 0.517
2.788AspPhe: 2.788 ± 0.517
2.788AspGly: 2.788 ± 0.517
0.929AspHis: 0.929 ± 0.765
2.788AspIle: 2.788 ± 1.922
3.717AspLys: 3.717 ± 1.157
7.435AspLeu: 7.435 ± 2.315
0.929AspMet: 0.929 ± 0.765
1.859AspAsn: 1.859 ± 1.53
3.717AspPro: 3.717 ± 0.248
0.0AspGln: 0.0 ± 0.0
2.788AspArg: 2.788 ± 0.517
6.506AspSer: 6.506 ± 3.08
0.929AspThr: 0.929 ± 0.641
0.929AspVal: 0.929 ± 0.765
0.929AspTrp: 0.929 ± 0.641
3.717AspTyr: 3.717 ± 0.248
0.0AspXaa: 0.0 ± 0.0
Glu
6.506GluAla: 6.506 ± 3.949
0.0GluCys: 0.0 ± 0.0
3.717GluAsp: 3.717 ± 1.157
2.788GluGlu: 2.788 ± 0.517
2.788GluPhe: 2.788 ± 0.889
0.929GluGly: 0.929 ± 0.641
0.929GluHis: 0.929 ± 0.641
4.647GluIle: 4.647 ± 0.393
2.788GluLys: 2.788 ± 0.889
3.717GluLeu: 3.717 ± 0.248
1.859GluMet: 1.859 ± 1.282
3.717GluAsn: 3.717 ± 0.248
0.929GluPro: 0.929 ± 0.641
0.0GluGln: 0.0 ± 0.0
3.717GluArg: 3.717 ± 1.157
4.647GluSer: 4.647 ± 1.013
2.788GluThr: 2.788 ± 0.517
2.788GluVal: 2.788 ± 0.517
0.0GluTrp: 0.0 ± 0.0
0.929GluTyr: 0.929 ± 0.641
0.0GluXaa: 0.0 ± 0.0
Phe
6.506PheAla: 6.506 ± 1.137
0.0PheCys: 0.0 ± 0.0
3.717PheAsp: 3.717 ± 2.563
2.788PheGlu: 2.788 ± 0.889
1.859PhePhe: 1.859 ± 0.124
4.647PheGly: 4.647 ± 1.013
1.859PheHis: 1.859 ± 0.124
4.647PheIle: 4.647 ± 1.798
2.788PheLys: 2.788 ± 0.517
6.506PheLeu: 6.506 ± 0.268
0.929PheMet: 0.929 ± 0.765
2.788PheAsn: 2.788 ± 0.889
5.576PhePro: 5.576 ± 1.778
0.929PheGln: 0.929 ± 0.641
1.859PheArg: 1.859 ± 0.124
1.859PheSer: 1.859 ± 0.124
2.788PheThr: 2.788 ± 1.922
0.929PheVal: 0.929 ± 0.641
1.859PheTrp: 1.859 ± 1.53
1.859PheTyr: 1.859 ± 1.53
0.0PheXaa: 0.0 ± 0.0
Gly
3.717GlyAla: 3.717 ± 1.157
0.0GlyCys: 0.0 ± 0.0
1.859GlyAsp: 1.859 ± 0.124
1.859GlyGlu: 1.859 ± 1.282
3.717GlyPhe: 3.717 ± 1.157
1.859GlyGly: 1.859 ± 1.282
2.788GlyHis: 2.788 ± 0.517
4.647GlyIle: 4.647 ± 0.393
2.788GlyLys: 2.788 ± 0.517
5.576GlyLeu: 5.576 ± 3.184
0.0GlyMet: 0.0 ± 0.484
1.859GlyAsn: 1.859 ± 1.282
1.859GlyPro: 1.859 ± 1.53
0.929GlyGln: 0.929 ± 0.765
0.0GlyArg: 0.0 ± 0.0
2.788GlySer: 2.788 ± 0.517
1.859GlyThr: 1.859 ± 0.124
1.859GlyVal: 1.859 ± 1.53
0.929GlyTrp: 0.929 ± 0.641
7.435GlyTyr: 7.435 ± 3.721
0.0GlyXaa: 0.0 ± 0.0
His
1.859HisAla: 1.859 ± 1.53
0.0HisCys: 0.0 ± 0.0
1.859HisAsp: 1.859 ± 1.282
0.929HisGlu: 0.929 ± 0.765
2.788HisPhe: 2.788 ± 1.922
2.788HisGly: 2.788 ± 1.922
0.929HisHis: 0.929 ± 0.765
2.788HisIle: 2.788 ± 2.295
0.0HisLys: 0.0 ± 0.0
1.859HisLeu: 1.859 ± 1.282
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
4.647HisPro: 4.647 ± 1.013
2.788HisGln: 2.788 ± 0.889
0.0HisArg: 0.0 ± 0.0
2.788HisSer: 2.788 ± 0.517
2.788HisThr: 2.788 ± 1.922
0.929HisVal: 0.929 ± 0.765
0.929HisTrp: 0.929 ± 0.641
3.717HisTyr: 3.717 ± 2.563
0.0HisXaa: 0.0 ± 0.0
Ile
2.788IleAla: 2.788 ± 0.889
0.929IleCys: 0.929 ± 0.641
1.859IleAsp: 1.859 ± 1.282
3.717IleGlu: 3.717 ± 1.157
2.788IlePhe: 2.788 ± 0.517
5.576IleGly: 5.576 ± 1.033
3.717IleHis: 3.717 ± 2.563
3.717IleIle: 3.717 ± 1.654
3.717IleLys: 3.717 ± 0.248
5.576IleLeu: 5.576 ± 0.372
0.0IleMet: 0.0 ± 0.0
2.788IleAsn: 2.788 ± 0.517
4.647IlePro: 4.647 ± 1.013
3.717IleGln: 3.717 ± 1.654
1.859IleArg: 1.859 ± 1.282
2.788IleSer: 2.788 ± 0.517
3.717IleThr: 3.717 ± 1.654
1.859IleVal: 1.859 ± 1.282
0.929IleTrp: 0.929 ± 0.641
3.717IleTyr: 3.717 ± 1.157
0.0IleXaa: 0.0 ± 0.0
Lys
2.788LysAla: 2.788 ± 0.889
0.0LysCys: 0.0 ± 0.0
1.859LysAsp: 1.859 ± 1.282
0.929LysGlu: 0.929 ± 0.765
1.859LysPhe: 1.859 ± 0.124
1.859LysGly: 1.859 ± 1.53
3.717LysHis: 3.717 ± 1.157
3.717LysIle: 3.717 ± 1.157
0.929LysLys: 0.929 ± 0.765
2.788LysLeu: 2.788 ± 0.517
0.0LysMet: 0.0 ± 0.0
1.859LysAsn: 1.859 ± 0.124
6.506LysPro: 6.506 ± 0.268
0.929LysGln: 0.929 ± 0.765
1.859LysArg: 1.859 ± 1.282
5.576LysSer: 5.576 ± 2.439
1.859LysThr: 1.859 ± 1.53
0.929LysVal: 0.929 ± 0.641
1.859LysTrp: 1.859 ± 0.124
3.717LysTyr: 3.717 ± 1.157
0.0LysXaa: 0.0 ± 0.0
Leu
10.223LeuAla: 10.223 ± 5.603
1.859LeuCys: 1.859 ± 1.53
7.435LeuAsp: 7.435 ± 0.496
3.717LeuGlu: 3.717 ± 0.248
4.647LeuPhe: 4.647 ± 1.013
0.0LeuGly: 0.0 ± 0.0
3.717LeuHis: 3.717 ± 3.06
1.859LeuIle: 1.859 ± 0.124
7.435LeuLys: 7.435 ± 3.721
7.435LeuLeu: 7.435 ± 0.909
5.576LeuMet: 5.576 ± 1.033
1.859LeuAsn: 1.859 ± 0.124
9.294LeuPro: 9.294 ± 0.621
5.576LeuGln: 5.576 ± 2.439
9.294LeuArg: 9.294 ± 0.621
6.506LeuSer: 6.506 ± 2.543
2.788LeuThr: 2.788 ± 1.922
4.647LeuVal: 4.647 ± 1.798
1.859LeuTrp: 1.859 ± 1.282
3.717LeuTyr: 3.717 ± 1.157
0.0LeuXaa: 0.0 ± 0.0
Met
2.788MetAla: 2.788 ± 0.517
0.929MetCys: 0.929 ± 0.641
2.788MetAsp: 2.788 ± 2.295
0.0MetGlu: 0.0 ± 0.0
1.859MetPhe: 1.859 ± 1.282
0.929MetGly: 0.929 ± 0.641
0.0MetHis: 0.0 ± 0.0
1.859MetIle: 1.859 ± 1.282
2.788MetLys: 2.788 ± 0.889
4.647MetLeu: 4.647 ± 0.393
0.929MetMet: 0.929 ± 0.765
0.929MetAsn: 0.929 ± 0.765
1.859MetPro: 1.859 ± 1.282
0.0MetGln: 0.0 ± 0.0
1.859MetArg: 1.859 ± 0.124
0.0MetSer: 0.0 ± 0.0
1.859MetThr: 1.859 ± 1.282
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.929MetTyr: 0.929 ± 0.641
0.0MetXaa: 0.0 ± 0.0
Asn
2.788AsnAla: 2.788 ± 0.517
1.859AsnCys: 1.859 ± 1.282
0.0AsnAsp: 0.0 ± 0.0
3.717AsnGlu: 3.717 ± 1.157
4.647AsnPhe: 4.647 ± 2.419
2.788AsnGly: 2.788 ± 0.889
2.788AsnHis: 2.788 ± 0.889
7.435AsnIle: 7.435 ± 2.315
0.0AsnLys: 0.0 ± 0.0
5.576AsnLeu: 5.576 ± 1.778
0.0AsnMet: 0.0 ± 0.0
1.859AsnAsn: 1.859 ± 0.124
2.788AsnPro: 2.788 ± 0.889
0.929AsnGln: 0.929 ± 0.765
1.859AsnArg: 1.859 ± 0.124
2.788AsnSer: 2.788 ± 0.517
1.859AsnThr: 1.859 ± 1.282
1.859AsnVal: 1.859 ± 0.124
0.929AsnTrp: 0.929 ± 0.641
2.788AsnTyr: 2.788 ± 0.517
0.0AsnXaa: 0.0 ± 0.0
Pro
3.717ProAla: 3.717 ± 3.06
0.929ProCys: 0.929 ± 0.765
4.647ProAsp: 4.647 ± 1.798
5.576ProGlu: 5.576 ± 1.778
6.506ProPhe: 6.506 ± 2.543
5.576ProGly: 5.576 ± 0.372
0.929ProHis: 0.929 ± 0.641
5.576ProIle: 5.576 ± 1.778
1.859ProLys: 1.859 ± 1.53
4.647ProLeu: 4.647 ± 0.393
0.929ProMet: 0.929 ± 0.641
2.788ProAsn: 2.788 ± 0.889
1.859ProPro: 1.859 ± 1.53
1.859ProGln: 1.859 ± 0.124
0.929ProArg: 0.929 ± 0.641
6.506ProSer: 6.506 ± 1.674
5.576ProThr: 5.576 ± 1.778
3.717ProVal: 3.717 ± 1.654
0.929ProTrp: 0.929 ± 0.641
2.788ProTyr: 2.788 ± 0.889
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.859GlnCys: 1.859 ± 1.53
0.0GlnAsp: 0.0 ± 0.0
0.929GlnGlu: 0.929 ± 0.641
0.929GlnPhe: 0.929 ± 0.765
1.859GlnGly: 1.859 ± 1.282
0.929GlnHis: 0.929 ± 0.641
2.788GlnIle: 2.788 ± 0.517
1.859GlnLys: 1.859 ± 0.124
2.788GlnLeu: 2.788 ± 1.922
0.929GlnMet: 0.929 ± 0.641
1.859GlnAsn: 1.859 ± 1.282
1.859GlnPro: 1.859 ± 1.53
0.929GlnGln: 0.929 ± 0.765
0.929GlnArg: 0.929 ± 0.641
0.0GlnSer: 0.0 ± 0.0
2.788GlnThr: 2.788 ± 0.517
4.647GlnVal: 4.647 ± 3.825
0.929GlnTrp: 0.929 ± 0.641
0.929GlnTyr: 0.929 ± 0.765
0.0GlnXaa: 0.0 ± 0.0
Arg
2.788ArgAla: 2.788 ± 2.295
0.0ArgCys: 0.0 ± 0.0
3.717ArgAsp: 3.717 ± 1.157
2.788ArgGlu: 2.788 ± 0.517
2.788ArgPhe: 2.788 ± 0.517
3.717ArgGly: 3.717 ± 0.248
2.788ArgHis: 2.788 ± 1.922
0.929ArgIle: 0.929 ± 0.641
2.788ArgLys: 2.788 ± 0.517
6.506ArgLeu: 6.506 ± 1.137
2.788ArgMet: 2.788 ± 1.922
1.859ArgAsn: 1.859 ± 1.282
0.929ArgPro: 0.929 ± 0.765
1.859ArgGln: 1.859 ± 1.282
4.647ArgArg: 4.647 ± 1.013
6.506ArgSer: 6.506 ± 0.268
2.788ArgThr: 2.788 ± 0.517
1.859ArgVal: 1.859 ± 1.282
0.0ArgTrp: 0.0 ± 0.0
1.859ArgTyr: 1.859 ± 1.282
0.0ArgXaa: 0.0 ± 0.0
Ser
2.788SerAla: 2.788 ± 2.295
0.0SerCys: 0.0 ± 0.0
6.506SerAsp: 6.506 ± 0.268
3.717SerGlu: 3.717 ± 1.157
0.0SerPhe: 0.0 ± 0.0
4.647SerGly: 4.647 ± 0.393
2.788SerHis: 2.788 ± 0.517
3.717SerIle: 3.717 ± 0.248
2.788SerLys: 2.788 ± 0.889
13.941SerLeu: 13.941 ± 1.178
2.788SerMet: 2.788 ± 0.358
1.859SerAsn: 1.859 ± 0.124
3.717SerPro: 3.717 ± 0.248
2.788SerGln: 2.788 ± 0.889
5.576SerArg: 5.576 ± 1.033
7.435SerSer: 7.435 ± 3.308
7.435SerThr: 7.435 ± 0.496
0.0SerVal: 0.0 ± 0.0
0.929SerTrp: 0.929 ± 0.641
3.717SerTyr: 3.717 ± 1.157
0.0SerXaa: 0.0 ± 0.0
Thr
4.647ThrAla: 4.647 ± 2.419
0.929ThrCys: 0.929 ± 0.765
1.859ThrAsp: 1.859 ± 0.124
0.0ThrGlu: 0.0 ± 0.0
4.647ThrPhe: 4.647 ± 0.393
2.788ThrGly: 2.788 ± 0.517
1.859ThrHis: 1.859 ± 0.124
2.788ThrIle: 2.788 ± 1.922
1.859ThrLys: 1.859 ± 1.282
6.506ThrLeu: 6.506 ± 0.268
0.929ThrMet: 0.929 ± 0.641
5.576ThrAsn: 5.576 ± 1.033
0.0ThrPro: 0.0 ± 0.0
0.929ThrGln: 0.929 ± 0.641
3.717ThrArg: 3.717 ± 1.157
3.717ThrSer: 3.717 ± 0.248
2.788ThrThr: 2.788 ± 1.922
5.576ThrVal: 5.576 ± 1.033
0.0ThrTrp: 0.0 ± 0.0
0.929ThrTyr: 0.929 ± 0.765
0.0ThrXaa: 0.0 ± 0.0
Val
3.717ValAla: 3.717 ± 1.654
0.0ValCys: 0.0 ± 0.0
3.717ValAsp: 3.717 ± 1.157
2.788ValGlu: 2.788 ± 0.517
1.859ValPhe: 1.859 ± 0.124
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
1.859ValIle: 1.859 ± 1.282
0.0ValLys: 0.0 ± 0.0
4.647ValLeu: 4.647 ± 0.393
2.788ValMet: 2.788 ± 0.517
1.859ValAsn: 1.859 ± 1.53
0.929ValPro: 0.929 ± 0.641
0.929ValGln: 0.929 ± 0.641
2.788ValArg: 2.788 ± 0.889
3.717ValSer: 3.717 ± 0.248
2.788ValThr: 2.788 ± 0.889
1.859ValVal: 1.859 ± 1.53
0.0ValTrp: 0.0 ± 0.0
0.929ValTyr: 0.929 ± 0.641
0.0ValXaa: 0.0 ± 0.0
Trp
1.859TrpAla: 1.859 ± 1.282
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.929TrpPhe: 0.929 ± 0.765
0.929TrpGly: 0.929 ± 0.641
0.0TrpHis: 0.0 ± 0.0
0.929TrpIle: 0.929 ± 0.765
0.929TrpLys: 0.929 ± 0.641
0.0TrpLeu: 0.0 ± 0.0
0.929TrpMet: 0.929 ± 0.641
3.717TrpAsn: 3.717 ± 1.157
1.859TrpPro: 1.859 ± 1.282
0.929TrpGln: 0.929 ± 0.641
0.0TrpArg: 0.0 ± 0.0
1.859TrpSer: 1.859 ± 0.124
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.717TyrAla: 3.717 ± 1.157
0.0TyrCys: 0.0 ± 0.0
0.929TyrAsp: 0.929 ± 0.641
0.929TyrGlu: 0.929 ± 0.641
5.576TyrPhe: 5.576 ± 2.439
1.859TyrGly: 1.859 ± 0.124
1.859TyrHis: 1.859 ± 0.124
1.859TyrIle: 1.859 ± 1.53
2.788TyrLys: 2.788 ± 0.517
3.717TyrLeu: 3.717 ± 1.654
0.0TyrMet: 0.0 ± 0.0
4.647TyrAsn: 4.647 ± 1.798
4.647TyrPro: 4.647 ± 0.393
1.859TyrGln: 1.859 ± 1.282
4.647TyrArg: 4.647 ± 3.204
3.717TyrSer: 3.717 ± 1.157
0.0TyrThr: 0.0 ± 0.0
1.859TyrVal: 1.859 ± 1.282
0.929TyrTrp: 0.929 ± 0.641
3.717TyrTyr: 3.717 ± 0.248
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1077 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski