Amino acid dipepetide frequency for Afipia broomeae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.166AlaAla: 16.166 ± 0.126	1.091AlaCys: 1.091 ± 0.024	6.335AlaAsp: 6.335 ± 0.056	6.482AlaGlu: 6.482 ± 0.055	4.436AlaPhe: 4.436 ± 0.043	9.795AlaGly: 9.795 ± 0.067	2.16AlaHis: 2.16 ± 0.032	6.83AlaIle: 6.83 ± 0.059	4.699AlaLys: 4.699 ± 0.059	12.432AlaLeu: 12.432 ± 0.094	3.43AlaMet: 3.43 ± 0.046	3.187AlaAsn: 3.187 ± 0.039	5.429AlaPro: 5.429 ± 0.062	3.902AlaGln: 3.902 ± 0.044	7.856AlaArg: 7.856 ± 0.074	6.978AlaSer: 6.978 ± 0.064	6.27AlaThr: 6.27 ± 0.054	8.708AlaVal: 8.708 ± 0.064	1.41AlaTrp: 1.41 ± 0.025	2.574AlaTyr: 2.574 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.992CysAla: 0.992 ± 0.021	0.128CysCys: 0.128 ± 0.008	0.521CysAsp: 0.521 ± 0.016	0.441CysGlu: 0.441 ± 0.014	0.374CysPhe: 0.374 ± 0.011	0.967CysGly: 0.967 ± 0.022	0.246CysHis: 0.246 ± 0.01	0.45CysIle: 0.45 ± 0.017	0.243CysLys: 0.243 ± 0.01	0.805CysLeu: 0.805 ± 0.02	0.181CysMet: 0.181 ± 0.009	0.235CysAsn: 0.235 ± 0.01	0.424CysPro: 0.424 ± 0.014	0.22CysGln: 0.22 ± 0.009	0.609CysArg: 0.609 ± 0.017	0.528CysSer: 0.528 ± 0.016	0.464CysThr: 0.464 ± 0.016	0.658CysVal: 0.658 ± 0.017	0.118CysTrp: 0.118 ± 0.007	0.232CysTyr: 0.232 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.343AspAla: 6.343 ± 0.051	0.492AspCys: 0.492 ± 0.016	3.088AspAsp: 3.088 ± 0.042	3.075AspGlu: 3.075 ± 0.036	2.179AspPhe: 2.179 ± 0.029	4.711AspGly: 4.711 ± 0.048	1.291AspHis: 1.291 ± 0.023	3.173AspIle: 3.173 ± 0.042	1.94AspLys: 1.94 ± 0.031	5.48AspLeu: 5.48 ± 0.053	1.241AspMet: 1.241 ± 0.022	1.397AspAsn: 1.397 ± 0.025	3.275AspPro: 3.275 ± 0.04	1.824AspGln: 1.824 ± 0.031	3.981AspArg: 3.981 ± 0.042	2.287AspSer: 2.287 ± 0.031	2.509AspThr: 2.509 ± 0.037	4.268AspVal: 4.268 ± 0.041	0.843AspTrp: 0.843 ± 0.019	1.5AspTyr: 1.5 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	6.409GluAla: 6.409 ± 0.057	0.359GluCys: 0.359 ± 0.014	2.315GluAsp: 2.315 ± 0.038	2.427GluGlu: 2.427 ± 0.035	1.866GluPhe: 1.866 ± 0.032	3.554GluGly: 3.554 ± 0.039	1.144GluHis: 1.144 ± 0.026	3.459GluIle: 3.459 ± 0.044	2.259GluLys: 2.259 ± 0.036	5.097GluLeu: 5.097 ± 0.047	1.372GluMet: 1.372 ± 0.023	1.512GluAsn: 1.512 ± 0.025	2.503GluPro: 2.503 ± 0.039	2.07GluGln: 2.07 ± 0.033	4.304GluArg: 4.304 ± 0.047	2.396GluSer: 2.396 ± 0.033	3.095GluThr: 3.095 ± 0.039	3.525GluVal: 3.525 ± 0.034	0.664GluTrp: 0.664 ± 0.019	1.019GluTyr: 1.019 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.847PheAla: 4.847 ± 0.054	0.424PheCys: 0.424 ± 0.014	2.592PheAsp: 2.592 ± 0.034	2.078PheGlu: 2.078 ± 0.031	1.57PhePhe: 1.57 ± 0.03	3.996PheGly: 3.996 ± 0.042	0.78PheHis: 0.78 ± 0.024	1.88PheIle: 1.88 ± 0.031	1.178PheLys: 1.178 ± 0.025	3.447PheLeu: 3.447 ± 0.051	0.836PheMet: 0.836 ± 0.019	1.22PheAsn: 1.22 ± 0.025	1.746PhePro: 1.746 ± 0.028	1.05PheGln: 1.05 ± 0.021	2.272PheArg: 2.272 ± 0.029	2.468PheSer: 2.468 ± 0.03	2.085PheThr: 2.085 ± 0.035	3.143PheVal: 3.143 ± 0.042	0.554PheTrp: 0.554 ± 0.016	0.965PheTyr: 0.965 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	8.803GlyAla: 8.803 ± 0.065	0.846GlyCys: 0.846 ± 0.023	4.12GlyAsp: 4.12 ± 0.041	4.122GlyGlu: 4.122 ± 0.041	3.738GlyPhe: 3.738 ± 0.042	6.986GlyGly: 6.986 ± 0.086	1.857GlyHis: 1.857 ± 0.032	4.896GlyIle: 4.896 ± 0.058	3.462GlyLys: 3.462 ± 0.047	8.501GlyLeu: 8.501 ± 0.067	2.209GlyMet: 2.209 ± 0.03	2.388GlyAsn: 2.388 ± 0.045	3.563GlyPro: 3.563 ± 0.043	2.721GlyGln: 2.721 ± 0.04	5.506GlyArg: 5.506 ± 0.055	4.958GlySer: 4.958 ± 0.058	4.533GlyThr: 4.533 ± 0.06	6.172GlyVal: 6.172 ± 0.056	1.357GlyTrp: 1.357 ± 0.028	2.4GlyTyr: 2.4 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	2.258HisAla: 2.258 ± 0.032	0.231HisCys: 0.231 ± 0.011	1.23HisAsp: 1.23 ± 0.025	0.993HisGlu: 0.993 ± 0.021	0.895HisPhe: 0.895 ± 0.021	1.911HisGly: 1.911 ± 0.032	0.586HisHis: 0.586 ± 0.018	1.0HisIle: 1.0 ± 0.022	0.514HisLys: 0.514 ± 0.016	2.026HisLeu: 2.026 ± 0.032	0.504HisMet: 0.504 ± 0.015	0.529HisAsn: 0.529 ± 0.016	1.349HisPro: 1.349 ± 0.03	0.626HisGln: 0.626 ± 0.018	1.46HisArg: 1.46 ± 0.028	1.062HisSer: 1.062 ± 0.026	0.865HisThr: 0.865 ± 0.02	1.523HisVal: 1.523 ± 0.028	0.346HisTrp: 0.346 ± 0.011	0.571HisTyr: 0.571 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	7.822IleAla: 7.822 ± 0.069	0.593IleCys: 0.593 ± 0.015	3.802IleAsp: 3.802 ± 0.042	3.625IleGlu: 3.625 ± 0.042	1.988IlePhe: 1.988 ± 0.034	5.343IleGly: 5.343 ± 0.046	0.937IleHis: 0.937 ± 0.023	2.574IleIle: 2.574 ± 0.037	1.883IleLys: 1.883 ± 0.033	4.563IleLeu: 4.563 ± 0.053	1.08IleMet: 1.08 ± 0.022	1.64IleAsn: 1.64 ± 0.03	2.556IlePro: 2.556 ± 0.036	1.332IleGln: 1.332 ± 0.029	3.283IleArg: 3.283 ± 0.036	3.434IleSer: 3.434 ± 0.037	2.838IleThr: 2.838 ± 0.037	4.73IleVal: 4.73 ± 0.05	0.67IleTrp: 0.67 ± 0.018	1.296IleTyr: 1.296 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	4.296LysAla: 4.296 ± 0.05	0.217LysCys: 0.217 ± 0.011	1.854LysAsp: 1.854 ± 0.033	1.641LysGlu: 1.641 ± 0.031	1.22LysPhe: 1.22 ± 0.022	2.655LysGly: 2.655 ± 0.036	0.727LysHis: 0.727 ± 0.02	2.237LysIle: 2.237 ± 0.035	1.636LysLys: 1.636 ± 0.033	3.805LysLeu: 3.805 ± 0.05	0.966LysMet: 0.966 ± 0.023	1.076LysAsn: 1.076 ± 0.024	2.443LysPro: 2.443 ± 0.04	1.312LysGln: 1.312 ± 0.026	2.549LysArg: 2.549 ± 0.036	2.291LysSer: 2.291 ± 0.03	2.257LysThr: 2.257 ± 0.034	2.628LysVal: 2.628 ± 0.036	0.46LysTrp: 0.46 ± 0.014	0.824LysTyr: 0.824 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	12.746LeuAla: 12.746 ± 0.087	0.915LeuCys: 0.915 ± 0.022	5.471LeuAsp: 5.471 ± 0.048	4.65LeuGlu: 4.65 ± 0.053	3.746LeuPhe: 3.746 ± 0.041	8.123LeuGly: 8.123 ± 0.068	1.855LeuHis: 1.855 ± 0.032	5.363LeuIle: 5.363 ± 0.059	3.857LeuLys: 3.857 ± 0.046	9.415LeuLeu: 9.415 ± 0.08	2.364LeuMet: 2.364 ± 0.032	2.86LeuAsn: 2.86 ± 0.038	5.387LeuPro: 5.387 ± 0.049	2.904LeuGln: 2.904 ± 0.035	6.532LeuArg: 6.532 ± 0.069	6.547LeuSer: 6.547 ± 0.059	5.65LeuThr: 5.65 ± 0.054	7.402LeuVal: 7.402 ± 0.069	1.124LeuTrp: 1.124 ± 0.021	1.986LeuTyr: 1.986 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.902MetAla: 2.902 ± 0.038	0.162MetCys: 0.162 ± 0.009	1.01MetAsp: 1.01 ± 0.023	0.963MetGlu: 0.963 ± 0.019	0.847MetPhe: 0.847 ± 0.019	1.648MetGly: 1.648 ± 0.025	0.46MetHis: 0.46 ± 0.014	1.488MetIle: 1.488 ± 0.025	1.104MetLys: 1.104 ± 0.021	2.576MetLeu: 2.576 ± 0.035	0.708MetMet: 0.708 ± 0.02	0.814MetAsn: 0.814 ± 0.016	1.553MetPro: 1.553 ± 0.027	0.876MetGln: 0.876 ± 0.018	1.774MetArg: 1.774 ± 0.03	1.777MetSer: 1.777 ± 0.026	1.916MetThr: 1.916 ± 0.027	1.696MetVal: 1.696 ± 0.028	0.225MetTrp: 0.225 ± 0.01	0.377MetTyr: 0.377 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.383AsnAla: 3.383 ± 0.04	0.281AsnCys: 0.281 ± 0.012	1.556AsnAsp: 1.556 ± 0.026	1.395AsnGlu: 1.395 ± 0.026	1.164AsnPhe: 1.164 ± 0.023	2.567AsnGly: 2.567 ± 0.047	0.551AsnHis: 0.551 ± 0.016	1.64AsnIle: 1.64 ± 0.028	0.944AsnLys: 0.944 ± 0.021	2.77AsnLeu: 2.77 ± 0.038	0.687AsnMet: 0.687 ± 0.019	0.878AsnAsn: 0.878 ± 0.024	1.924AsnPro: 1.924 ± 0.029	0.833AsnGln: 0.833 ± 0.024	1.798AsnArg: 1.798 ± 0.029	1.566AsnSer: 1.566 ± 0.031	1.415AsnThr: 1.415 ± 0.029	2.248AsnVal: 2.248 ± 0.031	0.457AsnTrp: 0.457 ± 0.015	0.791AsnTyr: 0.791 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.159ProAla: 6.159 ± 0.06	0.305ProCys: 0.305 ± 0.013	3.547ProAsp: 3.547 ± 0.038	3.205ProGlu: 3.205 ± 0.038	2.066ProPhe: 2.066 ± 0.033	4.357ProGly: 4.357 ± 0.048	1.072ProHis: 1.072 ± 0.022	2.641ProIle: 2.641 ± 0.042	2.034ProLys: 2.034 ± 0.034	4.729ProLeu: 4.729 ± 0.049	1.22ProMet: 1.22 ± 0.021	1.618ProAsn: 1.618 ± 0.023	2.894ProPro: 2.894 ± 0.047	1.742ProGln: 1.742 ± 0.028	2.999ProArg: 2.999 ± 0.041	3.19ProSer: 3.19 ± 0.039	2.671ProThr: 2.671 ± 0.041	4.091ProVal: 4.091 ± 0.043	0.687ProTrp: 0.687 ± 0.021	1.283ProTyr: 1.283 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	3.839GlnAla: 3.839 ± 0.05	0.247GlnCys: 0.247 ± 0.011	1.392GlnAsp: 1.392 ± 0.024	1.332GlnGlu: 1.332 ± 0.026	1.236GlnPhe: 1.236 ± 0.023	2.318GlnGly: 2.318 ± 0.036	0.655GlnHis: 0.655 ± 0.017	1.965GlnIle: 1.965 ± 0.027	1.198GlnLys: 1.198 ± 0.026	3.085GlnLeu: 3.085 ± 0.042	0.892GlnMet: 0.892 ± 0.02	0.982GlnAsn: 0.982 ± 0.019	1.872GlnPro: 1.872 ± 0.03	1.336GlnGln: 1.336 ± 0.034	2.376GlnArg: 2.376 ± 0.033	1.947GlnSer: 1.947 ± 0.034	1.808GlnThr: 1.808 ± 0.034	2.169GlnVal: 2.169 ± 0.032	0.454GlnTrp: 0.454 ± 0.016	0.692GlnTyr: 0.692 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	7.297ArgAla: 7.297 ± 0.071	0.528ArgCys: 0.528 ± 0.018	3.948ArgAsp: 3.948 ± 0.049	3.735ArgGlu: 3.735 ± 0.044	2.702ArgPhe: 2.702 ± 0.032	4.645ArgGly: 4.645 ± 0.05	1.592ArgHis: 1.592 ± 0.029	3.928ArgIle: 3.928 ± 0.044	2.578ArgLys: 2.578 ± 0.039	7.153ArgLeu: 7.153 ± 0.065	1.735ArgMet: 1.735 ± 0.03	2.028ArgAsn: 2.028 ± 0.033	3.352ArgPro: 3.352 ± 0.041	2.307ArgGln: 2.307 ± 0.031	5.121ArgArg: 5.121 ± 0.06	3.882ArgSer: 3.882 ± 0.042	3.285ArgThr: 3.285 ± 0.033	4.513ArgVal: 4.513 ± 0.044	0.991ArgTrp: 0.991 ± 0.018	1.721ArgTyr: 1.721 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	6.713SerAla: 6.713 ± 0.065	0.519SerCys: 0.519 ± 0.015	3.307SerAsp: 3.307 ± 0.042	2.984SerGlu: 2.984 ± 0.037	2.538SerPhe: 2.538 ± 0.034	5.731SerGly: 5.731 ± 0.066	1.226SerHis: 1.226 ± 0.024	3.288SerIle: 3.288 ± 0.034	1.995SerLys: 1.995 ± 0.031	5.777SerLeu: 5.777 ± 0.057	1.46SerMet: 1.46 ± 0.026	1.652SerAsn: 1.652 ± 0.029	3.121SerPro: 3.121 ± 0.039	1.773SerGln: 1.773 ± 0.028	3.751SerArg: 3.751 ± 0.047	3.791SerSer: 3.791 ± 0.061	3.027SerThr: 3.027 ± 0.045	4.355SerVal: 4.355 ± 0.05	0.8SerTrp: 0.8 ± 0.02	1.454SerTyr: 1.454 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	6.259ThrAla: 6.259 ± 0.058	0.411ThrCys: 0.411 ± 0.013	2.734ThrAsp: 2.734 ± 0.036	2.551ThrGlu: 2.551 ± 0.036	2.148ThrPhe: 2.148 ± 0.032	4.975ThrGly: 4.975 ± 0.058	1.032ThrHis: 1.032 ± 0.021	3.162ThrIle: 3.162 ± 0.046	1.797ThrLys: 1.797 ± 0.03	5.66ThrLeu: 5.66 ± 0.06	1.325ThrMet: 1.325 ± 0.024	1.492ThrAsn: 1.492 ± 0.032	3.346ThrPro: 3.346 ± 0.041	1.504ThrGln: 1.504 ± 0.028	3.206ThrArg: 3.206 ± 0.038	3.349ThrSer: 3.349 ± 0.044	3.0ThrThr: 3.0 ± 0.046	4.274ThrVal: 4.274 ± 0.056	0.657ThrTrp: 0.657 ± 0.02	1.241ThrTyr: 1.241 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	9.254ValAla: 9.254 ± 0.065	0.682ValCys: 0.682 ± 0.02	3.979ValAsp: 3.979 ± 0.041	4.032ValGlu: 4.032 ± 0.045	2.835ValPhe: 2.835 ± 0.037	5.748ValGly: 5.748 ± 0.058	1.45ValHis: 1.45 ± 0.027	4.236ValIle: 4.236 ± 0.046	2.571ValLys: 2.571 ± 0.036	7.442ValLeu: 7.442 ± 0.062	1.87ValMet: 1.87 ± 0.029	2.222ValAsn: 2.222 ± 0.035	3.823ValPro: 3.823 ± 0.039	2.138ValGln: 2.138 ± 0.033	4.757ValArg: 4.757 ± 0.053	4.599ValSer: 4.599 ± 0.047	4.51ValThr: 4.51 ± 0.059	6.217ValVal: 6.217 ± 0.064	0.896ValTrp: 0.896 ± 0.02	1.55ValTyr: 1.55 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.12TrpAla: 1.12 ± 0.023	0.14TrpCys: 0.14 ± 0.008	0.607TrpAsp: 0.607 ± 0.018	0.508TrpGlu: 0.508 ± 0.016	0.565TrpPhe: 0.565 ± 0.017	0.932TrpGly: 0.932 ± 0.021	0.364TrpHis: 0.364 ± 0.013	0.777TrpIle: 0.777 ± 0.02	0.49TrpLys: 0.49 ± 0.013	1.646TrpLeu: 1.646 ± 0.031	0.344TrpMet: 0.344 ± 0.014	0.477TrpAsn: 0.477 ± 0.016	0.706TrpPro: 0.706 ± 0.018	0.551TrpGln: 0.551 ± 0.015	1.149TrpArg: 1.149 ± 0.025	0.889TrpSer: 0.889 ± 0.021	0.807TrpThr: 0.807 ± 0.018	0.76TrpVal: 0.76 ± 0.022	0.228TrpTrp: 0.228 ± 0.009	0.287TrpTyr: 0.287 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.56TyrAla: 2.56 ± 0.04	0.267TyrCys: 0.267 ± 0.012	1.49TyrAsp: 1.49 ± 0.027	1.111TyrGlu: 1.111 ± 0.023	1.018TyrPhe: 1.018 ± 0.022	2.177TyrGly: 2.177 ± 0.032	0.492TyrHis: 0.492 ± 0.016	0.999TyrIle: 0.999 ± 0.021	0.711TyrLys: 0.711 ± 0.019	2.489TyrLeu: 2.489 ± 0.035	0.45TyrMet: 0.45 ± 0.014	0.64TyrAsn: 0.64 ± 0.018	1.245TyrPro: 1.245 ± 0.025	0.777TyrGln: 0.777 ± 0.019	1.758TyrArg: 1.758 ± 0.028	1.321TyrSer: 1.321 ± 0.024	1.12TyrThr: 1.12 ± 0.024	1.731TyrVal: 1.731 ± 0.026	0.407TyrTrp: 0.407 ± 0.015	0.66TyrTyr: 0.66 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7389 proteins (2250058 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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