Amino acid dipepetide frequency for Tortispora caseinolytica NRRL Y-17796

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.435AlaAla: 7.435 ± 0.102	0.996AlaCys: 0.996 ± 0.025	4.352AlaAsp: 4.352 ± 0.046	4.774AlaGlu: 4.774 ± 0.058	2.998AlaPhe: 2.998 ± 0.042	4.328AlaGly: 4.328 ± 0.055	1.605AlaHis: 1.605 ± 0.025	4.736AlaIle: 4.736 ± 0.052	4.419AlaLys: 4.419 ± 0.054	7.808AlaLeu: 7.808 ± 0.081	1.75AlaMet: 1.75 ± 0.032	3.181AlaAsn: 3.181 ± 0.044	3.545AlaPro: 3.545 ± 0.054	2.889AlaGln: 2.889 ± 0.046	3.863AlaArg: 3.863 ± 0.043	6.76AlaSer: 6.76 ± 0.074	4.445AlaThr: 4.445 ± 0.048	5.234AlaVal: 5.234 ± 0.068	0.777AlaTrp: 0.777 ± 0.021	2.446AlaTyr: 2.446 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.993CysAla: 0.993 ± 0.022	0.247CysCys: 0.247 ± 0.01	0.744CysAsp: 0.744 ± 0.022	0.664CysGlu: 0.664 ± 0.019	0.574CysPhe: 0.574 ± 0.02	0.906CysGly: 0.906 ± 0.027	0.312CysHis: 0.312 ± 0.014	0.903CysIle: 0.903 ± 0.024	0.638CysLys: 0.638 ± 0.019	1.323CysLeu: 1.323 ± 0.028	0.292CysMet: 0.292 ± 0.013	0.52CysAsn: 0.52 ± 0.017	0.623CysPro: 0.623 ± 0.022	0.414CysGln: 0.414 ± 0.015	0.722CysArg: 0.722 ± 0.019	1.084CysSer: 1.084 ± 0.025	0.735CysThr: 0.735 ± 0.019	0.836CysVal: 0.836 ± 0.022	0.143CysTrp: 0.143 ± 0.008	0.443CysTyr: 0.443 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.382AspAla: 4.382 ± 0.044	0.671AspCys: 0.671 ± 0.018	4.142AspAsp: 4.142 ± 0.069	4.167AspGlu: 4.167 ± 0.06	2.444AspPhe: 2.444 ± 0.036	3.091AspGly: 3.091 ± 0.045	1.239AspHis: 1.239 ± 0.028	4.32AspIle: 4.32 ± 0.045	2.759AspLys: 2.759 ± 0.039	5.725AspLeu: 5.725 ± 0.064	1.331AspMet: 1.331 ± 0.025	2.355AspAsn: 2.355 ± 0.037	3.212AspPro: 3.212 ± 0.048	1.94AspGln: 1.94 ± 0.031	2.695AspArg: 2.695 ± 0.039	5.297AspSer: 5.297 ± 0.065	3.288AspThr: 3.288 ± 0.045	3.674AspVal: 3.674 ± 0.038	0.681AspTrp: 0.681 ± 0.019	2.032AspTyr: 2.032 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	4.416GluAla: 4.416 ± 0.054	0.709GluCys: 0.709 ± 0.02	3.747GluAsp: 3.747 ± 0.056	4.668GluGlu: 4.668 ± 0.075	2.42GluPhe: 2.42 ± 0.036	2.773GluGly: 2.773 ± 0.044	1.267GluHis: 1.267 ± 0.027	3.89GluIle: 3.89 ± 0.045	3.682GluLys: 3.682 ± 0.052	6.087GluLeu: 6.087 ± 0.065	1.392GluMet: 1.392 ± 0.027	2.748GluAsn: 2.748 ± 0.037	2.579GluPro: 2.579 ± 0.043	2.453GluGln: 2.453 ± 0.039	3.213GluArg: 3.213 ± 0.049	5.171GluSer: 5.171 ± 0.052	3.545GluThr: 3.545 ± 0.042	3.512GluVal: 3.512 ± 0.043	0.748GluTrp: 0.748 ± 0.02	2.227GluTyr: 2.227 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.159PheAla: 3.159 ± 0.042	0.603PheCys: 0.603 ± 0.016	2.683PheAsp: 2.683 ± 0.039	2.437PheGlu: 2.437 ± 0.039	1.704PhePhe: 1.704 ± 0.03	2.58PheGly: 2.58 ± 0.043	0.899PheHis: 0.899 ± 0.022	2.28PheIle: 2.28 ± 0.037	1.919PheLys: 1.919 ± 0.031	3.806PheLeu: 3.806 ± 0.048	0.86PheMet: 0.86 ± 0.022	1.676PheAsn: 1.676 ± 0.03	1.808PhePro: 1.808 ± 0.035	1.379PheGln: 1.379 ± 0.025	1.916PheArg: 1.916 ± 0.032	3.669PheSer: 3.669 ± 0.049	2.253PheThr: 2.253 ± 0.034	2.716PheVal: 2.716 ± 0.037	0.541PheTrp: 0.541 ± 0.018	1.436PheTyr: 1.436 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	3.988GlyAla: 3.988 ± 0.057	0.754GlyCys: 0.754 ± 0.017	2.874GlyAsp: 2.874 ± 0.041	2.714GlyGlu: 2.714 ± 0.041	2.529GlyPhe: 2.529 ± 0.04	3.567GlyGly: 3.567 ± 0.07	1.277GlyHis: 1.277 ± 0.031	3.624GlyIle: 3.624 ± 0.044	3.17GlyLys: 3.17 ± 0.042	5.247GlyLeu: 5.247 ± 0.056	1.296GlyMet: 1.296 ± 0.032	2.204GlyAsn: 2.204 ± 0.032	2.318GlyPro: 2.318 ± 0.036	1.794GlyGln: 1.794 ± 0.032	2.873GlyArg: 2.873 ± 0.036	5.207GlySer: 5.207 ± 0.058	3.372GlyThr: 3.372 ± 0.046	3.668GlyVal: 3.668 ± 0.051	0.724GlyTrp: 0.724 ± 0.022	2.124GlyTyr: 2.124 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	1.555HisAla: 1.555 ± 0.03	0.329HisCys: 0.329 ± 0.014	1.192HisAsp: 1.192 ± 0.022	1.215HisGlu: 1.215 ± 0.023	0.91HisPhe: 0.91 ± 0.022	1.286HisGly: 1.286 ± 0.028	0.639HisHis: 0.639 ± 0.028	1.485HisIle: 1.485 ± 0.028	1.119HisLys: 1.119 ± 0.024	2.087HisLeu: 2.087 ± 0.035	0.5HisMet: 0.5 ± 0.016	0.967HisAsn: 0.967 ± 0.024	1.301HisPro: 1.301 ± 0.029	0.774HisGln: 0.774 ± 0.023	1.237HisArg: 1.237 ± 0.03	2.063HisSer: 2.063 ± 0.04	1.269HisThr: 1.269 ± 0.028	1.38HisVal: 1.38 ± 0.025	0.258HisTrp: 0.258 ± 0.011	0.77HisTyr: 0.77 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.105IleAla: 5.105 ± 0.061	0.933IleCys: 0.933 ± 0.025	4.207IleAsp: 4.207 ± 0.043	3.901IleGlu: 3.901 ± 0.051	2.247IlePhe: 2.247 ± 0.033	3.531IleGly: 3.531 ± 0.046	1.287IleHis: 1.287 ± 0.028	3.358IleIle: 3.358 ± 0.043	3.027IleLys: 3.027 ± 0.04	5.505IleLeu: 5.505 ± 0.064	1.266IleMet: 1.266 ± 0.024	2.351IleAsn: 2.351 ± 0.037	3.309IlePro: 3.309 ± 0.043	2.124IleGln: 2.124 ± 0.037	3.129IleArg: 3.129 ± 0.038	5.413IleSer: 5.413 ± 0.061	3.178IleThr: 3.178 ± 0.043	4.047IleVal: 4.047 ± 0.053	0.678IleTrp: 0.678 ± 0.021	1.882IleTyr: 1.882 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.18LysAla: 4.18 ± 0.05	0.656LysCys: 0.656 ± 0.018	3.153LysAsp: 3.153 ± 0.041	3.734LysGlu: 3.734 ± 0.047	2.018LysPhe: 2.018 ± 0.032	2.609LysGly: 2.609 ± 0.038	1.318LysHis: 1.318 ± 0.028	3.056LysIle: 3.056 ± 0.04	3.498LysLys: 3.498 ± 0.051	5.229LysLeu: 5.229 ± 0.059	1.134LysMet: 1.134 ± 0.025	2.219LysAsn: 2.219 ± 0.036	2.746LysPro: 2.746 ± 0.038	2.116LysGln: 2.116 ± 0.037	3.276LysArg: 3.276 ± 0.048	4.662LysSer: 4.662 ± 0.051	2.963LysThr: 2.963 ± 0.039	3.341LysVal: 3.341 ± 0.042	0.631LysTrp: 0.631 ± 0.016	2.067LysTyr: 2.067 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	7.608LeuAla: 7.608 ± 0.068	1.386LeuCys: 1.386 ± 0.028	5.685LeuAsp: 5.685 ± 0.058	5.827LeuGlu: 5.827 ± 0.065	3.906LeuPhe: 3.906 ± 0.052	4.976LeuGly: 4.976 ± 0.049	2.229LeuHis: 2.229 ± 0.038	5.163LeuIle: 5.163 ± 0.066	5.607LeuLys: 5.607 ± 0.061	9.201LeuLeu: 9.201 ± 0.089	1.93LeuMet: 1.93 ± 0.033	4.212LeuAsn: 4.212 ± 0.046	4.844LeuPro: 4.844 ± 0.054	3.743LeuGln: 3.743 ± 0.052	5.327LeuArg: 5.327 ± 0.054	8.55LeuSer: 8.55 ± 0.087	5.107LeuThr: 5.107 ± 0.059	5.832LeuVal: 5.832 ± 0.06	1.03LeuTrp: 1.03 ± 0.023	3.172LeuTyr: 3.172 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	1.754MetAla: 1.754 ± 0.031	0.293MetCys: 0.293 ± 0.012	1.188MetAsp: 1.188 ± 0.022	1.133MetGlu: 1.133 ± 0.025	0.94MetPhe: 0.94 ± 0.021	1.08MetGly: 1.08 ± 0.025	0.519MetHis: 0.519 ± 0.017	1.2MetIle: 1.2 ± 0.027	1.233MetLys: 1.233 ± 0.024	2.023MetLeu: 2.023 ± 0.028	0.45MetMet: 0.45 ± 0.017	1.054MetAsn: 1.054 ± 0.028	1.113MetPro: 1.113 ± 0.025	0.847MetGln: 0.847 ± 0.02	1.106MetArg: 1.106 ± 0.024	2.126MetSer: 2.126 ± 0.035	1.274MetThr: 1.274 ± 0.025	1.231MetVal: 1.231 ± 0.021	0.215MetTrp: 0.215 ± 0.012	0.707MetTyr: 0.707 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.315AsnAla: 3.315 ± 0.044	0.572AsnCys: 0.572 ± 0.02	2.632AsnAsp: 2.632 ± 0.04	2.61AsnGlu: 2.61 ± 0.038	1.505AsnPhe: 1.505 ± 0.027	2.622AsnGly: 2.622 ± 0.041	0.872AsnHis: 0.872 ± 0.023	2.88AsnIle: 2.88 ± 0.042	2.011AsnLys: 2.011 ± 0.033	3.719AsnLeu: 3.719 ± 0.039	0.993AsnMet: 0.993 ± 0.027	1.79AsnAsn: 1.79 ± 0.039	2.216AsnPro: 2.216 ± 0.034	1.363AsnGln: 1.363 ± 0.028	2.03AsnArg: 2.03 ± 0.029	3.736AsnSer: 3.736 ± 0.053	2.391AsnThr: 2.391 ± 0.041	2.82AsnVal: 2.82 ± 0.042	0.513AsnTrp: 0.513 ± 0.017	1.404AsnTyr: 1.404 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	3.963ProAla: 3.963 ± 0.058	0.464ProCys: 0.464 ± 0.016	3.131ProAsp: 3.131 ± 0.045	3.721ProGlu: 3.721 ± 0.046	1.928ProPhe: 1.928 ± 0.033	2.799ProGly: 2.799 ± 0.046	1.081ProHis: 1.081 ± 0.021	2.738ProIle: 2.738 ± 0.038	2.556ProLys: 2.556 ± 0.042	4.397ProLeu: 4.397 ± 0.054	0.92ProMet: 0.92 ± 0.021	2.03ProAsn: 2.03 ± 0.034	2.993ProPro: 2.993 ± 0.07	1.9ProGln: 1.9 ± 0.045	2.299ProArg: 2.299 ± 0.036	4.765ProSer: 4.765 ± 0.082	2.939ProThr: 2.939 ± 0.049	3.435ProVal: 3.435 ± 0.045	0.501ProTrp: 0.501 ± 0.018	1.608ProTyr: 1.608 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	2.676GlnAla: 2.676 ± 0.039	0.47GlnCys: 0.47 ± 0.019	1.78GlnAsp: 1.78 ± 0.03	2.157GlnGlu: 2.157 ± 0.037	1.582GlnPhe: 1.582 ± 0.028	1.768GlnGly: 1.768 ± 0.027	0.843GlnHis: 0.843 ± 0.022	2.322GlnIle: 2.322 ± 0.034	2.091GlnLys: 2.091 ± 0.035	3.676GlnLeu: 3.676 ± 0.047	0.845GlnMet: 0.845 ± 0.021	1.617GlnAsn: 1.617 ± 0.034	1.741GlnPro: 1.741 ± 0.042	1.946GlnGln: 1.946 ± 0.083	2.015GlnArg: 2.015 ± 0.033	3.08GlnSer: 3.08 ± 0.047	1.999GlnThr: 1.999 ± 0.033	2.056GlnVal: 2.056 ± 0.032	0.43GlnTrp: 0.43 ± 0.014	1.336GlnTyr: 1.336 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	3.671ArgAla: 3.671 ± 0.048	0.634ArgCys: 0.634 ± 0.018	2.717ArgAsp: 2.717 ± 0.04	2.961ArgGlu: 2.961 ± 0.053	2.117ArgPhe: 2.117 ± 0.032	2.538ArgGly: 2.538 ± 0.034	1.279ArgHis: 1.279 ± 0.021	3.223ArgIle: 3.223 ± 0.042	3.338ArgLys: 3.338 ± 0.047	5.136ArgLeu: 5.136 ± 0.057	1.204ArgMet: 1.204 ± 0.025	2.317ArgAsn: 2.317 ± 0.034	2.52ArgPro: 2.52 ± 0.039	2.067ArgGln: 2.067 ± 0.035	3.662ArgArg: 3.662 ± 0.06	4.584ArgSer: 4.584 ± 0.06	2.82ArgThr: 2.82 ± 0.039	3.024ArgVal: 3.024 ± 0.041	0.573ArgTrp: 0.573 ± 0.018	1.792ArgTyr: 1.792 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	7.231SerAla: 7.231 ± 0.088	0.957SerCys: 0.957 ± 0.023	5.37SerAsp: 5.37 ± 0.068	5.233SerGlu: 5.233 ± 0.061	3.613SerPhe: 3.613 ± 0.047	5.218SerGly: 5.218 ± 0.065	2.01SerHis: 2.01 ± 0.034	5.294SerIle: 5.294 ± 0.064	4.895SerLys: 4.895 ± 0.053	8.491SerLeu: 8.491 ± 0.087	1.861SerMet: 1.861 ± 0.03	3.835SerAsn: 3.835 ± 0.049	4.535SerPro: 4.535 ± 0.076	3.042SerGln: 3.042 ± 0.046	4.526SerArg: 4.526 ± 0.052	10.708SerSer: 10.708 ± 0.266	5.499SerThr: 5.499 ± 0.058	5.717SerVal: 5.717 ± 0.063	0.915SerTrp: 0.915 ± 0.022	2.693SerTyr: 2.693 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	4.835ThrAla: 4.835 ± 0.057	0.738ThrCys: 0.738 ± 0.021	3.276ThrAsp: 3.276 ± 0.045	3.277ThrGlu: 3.277 ± 0.042	2.216ThrPhe: 2.216 ± 0.036	3.558ThrGly: 3.558 ± 0.051	1.2ThrHis: 1.2 ± 0.025	3.438ThrIle: 3.438 ± 0.039	2.926ThrLys: 2.926 ± 0.037	5.316ThrLeu: 5.316 ± 0.062	1.12ThrMet: 1.12 ± 0.024	2.203ThrAsn: 2.203 ± 0.032	3.297ThrPro: 3.297 ± 0.055	1.819ThrGln: 1.819 ± 0.031	2.612ThrArg: 2.612 ± 0.036	4.984ThrSer: 4.984 ± 0.056	3.381ThrThr: 3.381 ± 0.048	4.045ThrVal: 4.045 ± 0.055	0.603ThrTrp: 0.603 ± 0.018	1.827ThrTyr: 1.827 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	4.809ValAla: 4.809 ± 0.056	0.976ValCys: 0.976 ± 0.025	3.715ValAsp: 3.715 ± 0.038	3.565ValGlu: 3.565 ± 0.052	2.717ValPhe: 2.717 ± 0.042	3.332ValGly: 3.332 ± 0.051	1.448ValHis: 1.448 ± 0.028	3.714ValIle: 3.714 ± 0.046	3.297ValLys: 3.297 ± 0.045	6.238ValLeu: 6.238 ± 0.062	1.319ValMet: 1.319 ± 0.026	2.557ValAsn: 2.557 ± 0.035	3.518ValPro: 3.518 ± 0.049	2.312ValGln: 2.312 ± 0.035	3.245ValArg: 3.245 ± 0.042	5.919ValSer: 5.919 ± 0.067	3.555ValThr: 3.555 ± 0.047	4.291ValVal: 4.291 ± 0.057	0.75ValTrp: 0.75 ± 0.021	2.334ValTyr: 2.334 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.765TrpAla: 0.765 ± 0.022	0.169TrpCys: 0.169 ± 0.009	0.72TrpAsp: 0.72 ± 0.022	0.541TrpGlu: 0.541 ± 0.016	0.472TrpPhe: 0.472 ± 0.017	0.63TrpGly: 0.63 ± 0.018	0.26TrpHis: 0.26 ± 0.013	0.733TrpIle: 0.733 ± 0.019	0.725TrpLys: 0.725 ± 0.018	1.041TrpLeu: 1.041 ± 0.024	0.253TrpMet: 0.253 ± 0.011	0.634TrpAsn: 0.634 ± 0.017	0.401TrpPro: 0.401 ± 0.013	0.373TrpGln: 0.373 ± 0.013	0.64TrpArg: 0.64 ± 0.019	0.939TrpSer: 0.939 ± 0.022	0.751TrpThr: 0.751 ± 0.02	0.635TrpVal: 0.635 ± 0.019	0.17TrpTrp: 0.17 ± 0.01	0.422TrpTyr: 0.422 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.503TyrAla: 2.503 ± 0.033	0.562TyrCys: 0.562 ± 0.017	2.135TyrAsp: 2.135 ± 0.028	1.946TyrGlu: 1.946 ± 0.033	1.484TyrPhe: 1.484 ± 0.03	2.129TyrGly: 2.129 ± 0.034	0.753TyrHis: 0.753 ± 0.018	2.124TyrIle: 2.124 ± 0.039	1.698TyrLys: 1.698 ± 0.031	3.278TyrLeu: 3.278 ± 0.043	0.769TyrMet: 0.769 ± 0.02	1.526TyrAsn: 1.526 ± 0.026	1.544TyrPro: 1.544 ± 0.026	1.136TyrGln: 1.136 ± 0.024	1.79TyrArg: 1.79 ± 0.032	2.926TyrSer: 2.926 ± 0.044	1.908TyrThr: 1.908 ± 0.03	2.116TyrVal: 2.116 ± 0.035	0.394TyrTrp: 0.394 ± 0.013	1.272TyrTyr: 1.272 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4657 proteins (2057799 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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