Amino acid dipepetide frequency for Wenzhou tombus-like virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.102AlaAla: 5.102 ± 0.969
0.0AlaCys: 0.0 ± 0.0
5.102AlaAsp: 5.102 ± 2.453
1.458AlaGlu: 1.458 ± 0.701
3.644AlaPhe: 3.644 ± 0.781
3.644AlaGly: 3.644 ± 3.148
1.458AlaHis: 1.458 ± 0.701
3.644AlaIle: 3.644 ± 0.653
2.187AlaLys: 2.187 ± 1.222
4.373AlaLeu: 4.373 ± 2.103
2.915AlaMet: 2.915 ± 0.547
5.831AlaAsn: 5.831 ± 1.409
5.102AlaPro: 5.102 ± 2.631
2.915AlaGln: 2.915 ± 2.259
2.187AlaArg: 2.187 ± 1.098
5.831AlaSer: 5.831 ± 3.083
4.373AlaThr: 4.373 ± 0.214
5.102AlaVal: 5.102 ± 1.617
0.729AlaTrp: 0.729 ± 0.644
3.644AlaTyr: 3.644 ± 1.618
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.729CysAsp: 0.729 ± 0.565
0.729CysGlu: 0.729 ± 0.644
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.729CysIle: 0.729 ± 0.565
0.729CysLys: 0.729 ± 0.63
0.729CysLeu: 0.729 ± 0.644
0.729CysMet: 0.729 ± 0.644
0.0CysAsn: 0.0 ± 0.0
0.729CysPro: 0.729 ± 0.63
0.729CysGln: 0.729 ± 0.644
0.0CysArg: 0.0 ± 0.0
2.187CysSer: 2.187 ± 1.075
1.458CysThr: 1.458 ± 0.601
0.729CysVal: 0.729 ± 0.644
0.0CysTrp: 0.0 ± 0.0
0.729CysTyr: 0.729 ± 0.63
0.0CysXaa: 0.0 ± 0.0
Asp
3.644AspAla: 3.644 ± 1.196
0.0AspCys: 0.0 ± 0.0
0.729AspAsp: 0.729 ± 0.644
3.644AspGlu: 3.644 ± 1.107
0.729AspPhe: 0.729 ± 0.565
2.187AspGly: 2.187 ± 1.098
1.458AspHis: 1.458 ± 0.701
3.644AspIle: 3.644 ± 0.431
2.187AspLys: 2.187 ± 1.049
3.644AspLeu: 3.644 ± 0.653
0.0AspMet: 0.0 ± 0.0
3.644AspAsn: 3.644 ± 1.948
2.187AspPro: 2.187 ± 0.107
1.458AspGln: 1.458 ± 1.129
3.644AspArg: 3.644 ± 1.395
2.915AspSer: 2.915 ± 1.202
3.644AspThr: 3.644 ± 1.107
2.915AspVal: 2.915 ± 0.569
0.0AspTrp: 0.0 ± 0.0
2.915AspTyr: 2.915 ± 1.076
0.0AspXaa: 0.0 ± 0.0
Glu
1.458GluAla: 1.458 ± 0.701
0.729GluCys: 0.729 ± 0.565
2.915GluAsp: 2.915 ± 1.599
3.644GluGlu: 3.644 ± 1.886
1.458GluPhe: 1.458 ± 1.289
1.458GluGly: 1.458 ± 1.259
0.729GluHis: 0.729 ± 0.565
2.187GluIle: 2.187 ± 1.098
2.187GluLys: 2.187 ± 1.222
5.102GluLeu: 5.102 ± 1.929
1.458GluMet: 1.458 ± 0.601
1.458GluAsn: 1.458 ± 0.701
1.458GluPro: 1.458 ± 1.129
0.729GluGln: 0.729 ± 0.644
3.644GluArg: 3.644 ± 2.447
2.187GluSer: 2.187 ± 1.026
2.187GluThr: 2.187 ± 1.222
2.187GluVal: 2.187 ± 1.026
1.458GluTrp: 1.458 ± 0.601
4.373GluTyr: 4.373 ± 1.803
0.0GluXaa: 0.0 ± 0.0
Phe
2.915PheAla: 2.915 ± 0.751
0.729PheCys: 0.729 ± 0.644
3.644PheAsp: 3.644 ± 0.781
2.915PheGlu: 2.915 ± 1.668
1.458PhePhe: 1.458 ± 1.129
4.373PheGly: 4.373 ± 1.165
0.729PheHis: 0.729 ± 0.644
0.729PheIle: 0.729 ± 0.644
4.373PheLys: 4.373 ± 2.196
0.0PheLeu: 0.0 ± 0.0
0.729PheMet: 0.729 ± 0.63
2.187PheAsn: 2.187 ± 1.222
4.373PhePro: 4.373 ± 1.323
2.915PheGln: 2.915 ± 1.622
0.0PheArg: 0.0 ± 0.0
2.187PheSer: 2.187 ± 1.889
2.915PheThr: 2.915 ± 0.569
2.187PheVal: 2.187 ± 1.222
1.458PheTrp: 1.458 ± 0.601
0.729PheTyr: 0.729 ± 0.565
0.0PheXaa: 0.0 ± 0.0
Gly
1.458GlyAla: 1.458 ± 1.129
0.729GlyCys: 0.729 ± 0.63
2.915GlyAsp: 2.915 ± 0.751
4.373GlyGlu: 4.373 ± 1.165
0.729GlyPhe: 0.729 ± 0.565
2.187GlyGly: 2.187 ± 1.026
0.729GlyHis: 0.729 ± 0.644
1.458GlyIle: 1.458 ± 0.538
4.373GlyLys: 4.373 ± 0.93
5.831GlyLeu: 5.831 ± 1.6
0.729GlyMet: 0.729 ± 0.644
1.458GlyAsn: 1.458 ± 0.538
2.915GlyPro: 2.915 ± 1.615
2.187GlyGln: 2.187 ± 1.075
0.729GlyArg: 0.729 ± 0.565
2.187GlySer: 2.187 ± 1.026
1.458GlyThr: 1.458 ± 0.538
2.187GlyVal: 2.187 ± 1.049
0.729GlyTrp: 0.729 ± 0.644
0.729GlyTyr: 0.729 ± 0.565
0.0GlyXaa: 0.0 ± 0.0
His
0.729HisAla: 0.729 ± 0.565
0.0HisCys: 0.0 ± 0.0
1.458HisAsp: 1.458 ± 1.129
0.0HisGlu: 0.0 ± 0.0
1.458HisPhe: 1.458 ± 1.289
0.0HisGly: 0.0 ± 0.0
1.458HisHis: 1.458 ± 0.538
0.729HisIle: 0.729 ± 0.63
1.458HisLys: 1.458 ± 0.538
3.644HisLeu: 3.644 ± 1.886
0.0HisMet: 0.0 ± 0.0
4.373HisAsn: 4.373 ± 2.196
0.729HisPro: 0.729 ± 0.565
1.458HisGln: 1.458 ± 1.289
2.187HisArg: 2.187 ± 1.075
2.187HisSer: 2.187 ± 1.075
0.729HisThr: 0.729 ± 0.565
0.729HisVal: 0.729 ± 0.565
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.915IleAla: 2.915 ± 0.569
0.0IleCys: 0.0 ± 0.0
4.373IleAsp: 4.373 ± 0.214
3.644IleGlu: 3.644 ± 0.781
3.644IlePhe: 3.644 ± 1.618
1.458IleGly: 1.458 ± 1.259
0.729IleHis: 0.729 ± 0.644
3.644IleIle: 3.644 ± 1.512
2.187IleLys: 2.187 ± 1.694
3.644IleLeu: 3.644 ± 2.447
1.458IleMet: 1.458 ± 0.538
5.831IleAsn: 5.831 ± 0.717
4.373IlePro: 4.373 ± 0.93
1.458IleGln: 1.458 ± 0.601
4.373IleArg: 4.373 ± 1.165
4.373IleSer: 4.373 ± 1.824
7.289IleThr: 7.289 ± 2.391
2.187IleVal: 2.187 ± 1.098
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
5.831LysAla: 5.831 ± 0.326
0.0LysCys: 0.0 ± 0.0
3.644LysAsp: 3.644 ± 1.107
2.187LysGlu: 2.187 ± 1.098
4.373LysPhe: 4.373 ± 1.04
0.729LysGly: 0.729 ± 0.644
1.458LysHis: 1.458 ± 0.701
4.373LysIle: 4.373 ± 1.04
8.746LysLys: 8.746 ± 0.698
5.102LysLeu: 5.102 ± 1.25
4.373LysMet: 4.373 ± 1.323
2.915LysAsn: 2.915 ± 1.202
1.458LysPro: 1.458 ± 0.601
2.187LysGln: 2.187 ± 1.049
4.373LysArg: 4.373 ± 2.678
3.644LysSer: 3.644 ± 1.886
7.289LysThr: 7.289 ± 3.01
4.373LysVal: 4.373 ± 0.214
1.458LysTrp: 1.458 ± 1.289
3.644LysTyr: 3.644 ± 0.431
0.0LysXaa: 0.0 ± 0.0
Leu
5.831LeuAla: 5.831 ± 0.866
2.915LeuCys: 2.915 ± 1.202
2.187LeuAsp: 2.187 ± 1.933
2.915LeuGlu: 2.915 ± 1.402
1.458LeuPhe: 1.458 ± 0.601
5.102LeuGly: 5.102 ± 0.524
2.915LeuHis: 2.915 ± 0.547
3.644LeuIle: 3.644 ± 1.395
6.56LeuLys: 6.56 ± 2.545
5.831LeuLeu: 5.831 ± 1.696
2.915LeuMet: 2.915 ± 0.476
5.831LeuAsn: 5.831 ± 0.866
2.915LeuPro: 2.915 ± 0.547
4.373LeuGln: 4.373 ± 1.137
5.102LeuArg: 5.102 ± 2.234
6.56LeuSer: 6.56 ± 1.184
2.915LeuThr: 2.915 ± 1.622
7.289LeuVal: 7.289 ± 1.297
2.187LeuTrp: 2.187 ± 1.026
1.458LeuTyr: 1.458 ± 0.601
0.0LeuXaa: 0.0 ± 0.0
Met
2.187MetAla: 2.187 ± 1.026
0.0MetCys: 0.0 ± 0.0
1.458MetAsp: 1.458 ± 1.129
3.644MetGlu: 3.644 ± 2.447
2.187MetPhe: 2.187 ± 1.933
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.729MetIle: 0.729 ± 0.63
0.729MetLys: 0.729 ± 0.63
2.915MetLeu: 2.915 ± 1.076
1.458MetMet: 1.458 ± 0.538
0.729MetAsn: 0.729 ± 0.565
0.729MetPro: 0.729 ± 0.63
0.729MetGln: 0.729 ± 0.644
0.0MetArg: 0.0 ± 0.0
3.644MetSer: 3.644 ± 1.618
2.915MetThr: 2.915 ± 1.599
2.187MetVal: 2.187 ± 1.222
0.0MetTrp: 0.0 ± 0.0
1.458MetTyr: 1.458 ± 0.538
0.0MetXaa: 0.0 ± 0.0
Asn
5.102AsnAla: 5.102 ± 2.631
2.187AsnCys: 2.187 ± 1.075
2.187AsnAsp: 2.187 ± 1.694
2.187AsnGlu: 2.187 ± 1.694
2.915AsnPhe: 2.915 ± 1.402
1.458AsnGly: 1.458 ± 0.601
1.458AsnHis: 1.458 ± 0.701
5.102AsnIle: 5.102 ± 0.969
5.831AsnLys: 5.831 ± 1.094
5.831AsnLeu: 5.831 ± 2.151
0.729AsnMet: 0.729 ± 0.565
3.644AsnAsn: 3.644 ± 1.512
4.373AsnPro: 4.373 ± 2.052
5.102AsnGln: 5.102 ± 3.053
4.373AsnArg: 4.373 ± 1.613
5.102AsnSer: 5.102 ± 0.858
3.644AsnThr: 3.644 ± 2.226
8.017AsnVal: 8.017 ± 3.571
0.0AsnTrp: 0.0 ± 0.0
2.187AsnTyr: 2.187 ± 1.933
0.0AsnXaa: 0.0 ± 0.0
Pro
3.644ProAla: 3.644 ± 1.107
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
2.187ProGlu: 2.187 ± 0.107
0.729ProPhe: 0.729 ± 0.565
2.187ProGly: 2.187 ± 1.026
0.0ProHis: 0.0 ± 0.0
8.017ProIle: 8.017 ± 0.791
2.915ProLys: 2.915 ± 2.518
2.915ProLeu: 2.915 ± 0.547
0.0ProMet: 0.0 ± 0.0
5.831ProAsn: 5.831 ± 2.798
6.56ProPro: 6.56 ± 2.716
5.102ProGln: 5.102 ± 2.301
0.729ProArg: 0.729 ± 0.644
2.915ProSer: 2.915 ± 1.622
9.475ProThr: 9.475 ± 3.561
4.373ProVal: 4.373 ± 1.613
0.729ProTrp: 0.729 ± 0.63
2.187ProTyr: 2.187 ± 1.049
0.0ProXaa: 0.0 ± 0.0
Gln
3.644GlnAla: 3.644 ± 0.431
0.729GlnCys: 0.729 ± 0.644
0.729GlnAsp: 0.729 ± 0.565
2.915GlnGlu: 2.915 ± 1.202
1.458GlnPhe: 1.458 ± 0.601
1.458GlnGly: 1.458 ± 1.129
2.915GlnHis: 2.915 ± 1.668
1.458GlnIle: 1.458 ± 0.538
1.458GlnLys: 1.458 ± 0.701
5.102GlnLeu: 5.102 ± 0.55
1.458GlnMet: 1.458 ± 0.604
2.187GlnAsn: 2.187 ± 1.694
8.017GlnPro: 8.017 ± 3.571
2.915GlnGln: 2.915 ± 2.259
2.187GlnArg: 2.187 ± 0.905
2.187GlnSer: 2.187 ± 1.049
2.915GlnThr: 2.915 ± 1.622
0.729GlnVal: 0.729 ± 0.565
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.644ArgAla: 3.644 ± 2.447
0.729ArgCys: 0.729 ± 0.644
0.729ArgAsp: 0.729 ± 0.644
1.458ArgGlu: 1.458 ± 0.538
2.187ArgPhe: 2.187 ± 0.107
1.458ArgGly: 1.458 ± 1.129
1.458ArgHis: 1.458 ± 0.701
1.458ArgIle: 1.458 ± 0.701
5.831ArgLys: 5.831 ± 2.798
5.102ArgLeu: 5.102 ± 2.234
1.458ArgMet: 1.458 ± 0.601
2.915ArgAsn: 2.915 ± 1.076
0.729ArgPro: 0.729 ± 0.565
0.729ArgGln: 0.729 ± 0.565
0.0ArgArg: 0.0 ± 0.0
5.102ArgSer: 5.102 ± 0.858
2.915ArgThr: 2.915 ± 1.615
4.373ArgVal: 4.373 ± 1.323
0.0ArgTrp: 0.0 ± 0.0
2.187ArgTyr: 2.187 ± 1.933
0.0ArgXaa: 0.0 ± 0.0
Ser
6.56SerAla: 6.56 ± 1.764
0.729SerCys: 0.729 ± 0.565
1.458SerAsp: 1.458 ± 1.259
1.458SerGlu: 1.458 ± 0.701
6.56SerPhe: 6.56 ± 1.85
7.289SerGly: 7.289 ± 2.659
1.458SerHis: 1.458 ± 0.538
4.373SerIle: 4.373 ± 1.803
5.831SerLys: 5.831 ± 1.696
5.102SerLeu: 5.102 ± 1.529
1.458SerMet: 1.458 ± 0.601
6.56SerAsn: 6.56 ± 3.077
2.187SerPro: 2.187 ± 1.075
0.0SerGln: 0.0 ± 0.0
2.915SerArg: 2.915 ± 0.751
6.56SerSer: 6.56 ± 2.747
5.831SerThr: 5.831 ± 4.094
3.644SerVal: 3.644 ± 3.148
0.729SerTrp: 0.729 ± 0.565
4.373SerTyr: 4.373 ± 1.803
0.0SerXaa: 0.0 ± 0.0
Thr
5.831ThrAla: 5.831 ± 1.139
0.729ThrCys: 0.729 ± 0.644
2.187ThrAsp: 2.187 ± 0.905
0.729ThrGlu: 0.729 ± 0.63
4.373ThrPhe: 4.373 ± 1.613
1.458ThrGly: 1.458 ± 0.601
0.729ThrHis: 0.729 ± 0.63
7.289ThrIle: 7.289 ± 1.446
8.746ThrLys: 8.746 ± 0.428
5.102ThrLeu: 5.102 ± 1.48
1.458ThrMet: 1.458 ± 1.129
5.831ThrAsn: 5.831 ± 2.528
2.915ThrPro: 2.915 ± 2.518
2.915ThrGln: 2.915 ± 0.751
2.915ThrArg: 2.915 ± 1.202
11.662ThrSer: 11.662 ± 5.367
10.933ThrThr: 10.933 ± 1.657
5.102ThrVal: 5.102 ± 2.301
0.0ThrTrp: 0.0 ± 0.0
1.458ThrTyr: 1.458 ± 1.259
0.0ThrXaa: 0.0 ± 0.0
Val
7.289ValAla: 7.289 ± 0.863
0.729ValCys: 0.729 ± 0.63
2.915ValAsp: 2.915 ± 0.569
0.0ValGlu: 0.0 ± 0.0
2.187ValPhe: 2.187 ± 1.222
2.915ValGly: 2.915 ± 0.569
2.187ValHis: 2.187 ± 1.694
2.187ValIle: 2.187 ± 1.075
3.644ValLys: 3.644 ± 1.395
4.373ValLeu: 4.373 ± 1.811
2.187ValMet: 2.187 ± 0.107
5.831ValAsn: 5.831 ± 2.138
5.831ValPro: 5.831 ± 1.285
4.373ValGln: 4.373 ± 2.052
2.915ValArg: 2.915 ± 1.599
2.915ValSer: 2.915 ± 0.751
5.102ValThr: 5.102 ± 1.886
4.373ValVal: 4.373 ± 1.613
2.915ValTrp: 2.915 ± 1.076
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.915TrpAsp: 2.915 ± 1.622
0.729TrpGlu: 0.729 ± 0.63
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.458TrpIle: 1.458 ± 0.601
0.729TrpLys: 0.729 ± 0.644
2.187TrpLeu: 2.187 ± 0.107
0.729TrpMet: 0.729 ± 0.646
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.729TrpArg: 0.729 ± 0.565
0.0TrpSer: 0.0 ± 0.0
0.729TrpThr: 0.729 ± 0.644
0.729TrpVal: 0.729 ± 0.63
0.0TrpTrp: 0.0 ± 0.0
0.729TrpTyr: 0.729 ± 0.565
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.458TyrAla: 1.458 ± 1.289
0.0TyrCys: 0.0 ± 0.0
2.915TyrAsp: 2.915 ± 0.569
2.187TyrGlu: 2.187 ± 1.075
0.0TyrPhe: 0.0 ± 0.0
0.729TyrGly: 0.729 ± 0.63
1.458TyrHis: 1.458 ± 0.701
0.729TyrIle: 0.729 ± 0.644
1.458TyrLys: 1.458 ± 0.601
4.373TyrLeu: 4.373 ± 3.079
0.729TyrMet: 0.729 ± 0.644
4.373TyrAsn: 4.373 ± 2.052
2.915TyrPro: 2.915 ± 0.569
2.187TyrGln: 2.187 ± 1.049
1.458TyrArg: 1.458 ± 0.538
0.729TyrSer: 0.729 ± 0.63
3.644TyrThr: 3.644 ± 0.653
1.458TyrVal: 1.458 ± 1.259
0.0TyrTrp: 0.0 ± 0.0
0.729TyrTyr: 0.729 ± 0.644
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1373 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski