Amino acid dipepetide frequency for Lihan tick virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.329AlaAla: 5.329 ± 7.248
1.523AlaCys: 1.523 ± 0.267
3.045AlaAsp: 3.045 ± 2.476
3.426AlaGlu: 3.426 ± 1.586
3.045AlaPhe: 3.045 ± 1.505
3.426AlaGly: 3.426 ± 0.357
2.284AlaHis: 2.284 ± 0.886
1.903AlaIle: 1.903 ± 0.09
4.187AlaLys: 4.187 ± 0.005
8.375AlaLeu: 8.375 ± 0.981
0.761AlaMet: 0.761 ± 0.352
1.142AlaAsn: 1.142 ± 0.529
3.045AlaPro: 3.045 ± 2.476
2.284AlaGln: 2.284 ± 0.886
3.807AlaArg: 3.807 ± 0.181
4.949AlaSer: 4.949 ± 1.319
3.426AlaThr: 3.426 ± 2.3
3.807AlaVal: 3.807 ± 2.124
0.761AlaTrp: 0.761 ± 0.352
2.665AlaTyr: 2.665 ± 0.262
0.0AlaXaa: 0.0 ± 0.0
Cys
0.381CysAla: 0.381 ± 0.176
0.0CysCys: 0.0 ± 0.0
0.381CysAsp: 0.381 ± 0.176
0.0CysGlu: 0.0 ± 0.0
0.761CysPhe: 0.761 ± 0.352
0.761CysGly: 0.761 ± 0.352
0.381CysHis: 0.381 ± 0.176
0.761CysIle: 0.761 ± 0.352
1.523CysLys: 1.523 ± 0.705
2.665CysLeu: 2.665 ± 2.652
1.523CysMet: 1.523 ± 0.705
0.0CysAsn: 0.0 ± 0.0
0.381CysPro: 0.381 ± 0.176
1.142CysGln: 1.142 ± 0.529
3.045CysArg: 3.045 ± 0.533
1.142CysSer: 1.142 ± 0.529
0.381CysThr: 0.381 ± 0.176
0.381CysVal: 0.381 ± 0.176
0.0CysTrp: 0.0 ± 0.0
0.381CysTyr: 0.381 ± 0.176
0.0CysXaa: 0.0 ± 0.0
Asp
1.142AspAla: 1.142 ± 0.443
0.381AspCys: 0.381 ± 0.176
5.329AspAsp: 5.329 ± 0.447
6.091AspGlu: 6.091 ± 0.095
3.045AspPhe: 3.045 ± 1.41
2.284AspGly: 2.284 ± 1.057
1.903AspHis: 1.903 ± 0.09
4.568AspIle: 4.568 ± 0.172
1.903AspLys: 1.903 ± 1.062
4.187AspLeu: 4.187 ± 0.967
1.142AspMet: 1.142 ± 0.529
1.523AspAsn: 1.523 ± 0.267
3.807AspPro: 3.807 ± 0.181
1.903AspGln: 1.903 ± 2.033
4.187AspArg: 4.187 ± 0.005
4.187AspSer: 4.187 ± 1.948
2.665AspThr: 2.665 ± 0.262
5.329AspVal: 5.329 ± 1.496
0.381AspTrp: 0.381 ± 0.176
2.284AspTyr: 2.284 ± 0.086
0.0AspXaa: 0.0 ± 0.0
Glu
5.329GluAla: 5.329 ± 1.496
1.142GluCys: 1.142 ± 0.443
5.71GluAsp: 5.71 ± 0.271
9.517GluGlu: 9.517 ± 0.452
4.187GluPhe: 4.187 ± 0.005
6.091GluGly: 6.091 ± 1.067
1.142GluHis: 1.142 ± 0.443
3.045GluIle: 3.045 ± 1.41
5.71GluLys: 5.71 ± 2.643
4.187GluLeu: 4.187 ± 1.938
2.284GluMet: 2.284 ± 0.086
1.142GluAsn: 1.142 ± 0.529
3.426GluPro: 3.426 ± 0.614
2.665GluGln: 2.665 ± 0.262
3.807GluArg: 3.807 ± 0.791
3.045GluSer: 3.045 ± 1.505
8.755GluThr: 8.755 ± 2.11
1.903GluVal: 1.903 ± 1.062
0.761GluTrp: 0.761 ± 0.619
1.142GluTyr: 1.142 ± 0.529
0.0GluXaa: 0.0 ± 0.0
Phe
1.523PheAla: 1.523 ± 0.267
0.761PheCys: 0.761 ± 0.352
3.045PheAsp: 3.045 ± 0.438
3.045PheGlu: 3.045 ± 1.41
1.523PhePhe: 1.523 ± 0.705
2.665PheGly: 2.665 ± 0.262
1.523PheHis: 1.523 ± 0.705
2.665PheIle: 2.665 ± 0.262
4.187PheLys: 4.187 ± 1.938
4.187PheLeu: 4.187 ± 0.967
1.142PheMet: 1.142 ± 0.443
1.903PheAsn: 1.903 ± 0.881
2.665PhePro: 2.665 ± 1.234
1.523PheGln: 1.523 ± 0.267
1.903PheArg: 1.903 ± 0.09
2.284PheSer: 2.284 ± 1.057
3.426PheThr: 3.426 ± 1.586
2.665PheVal: 2.665 ± 0.262
0.761PheTrp: 0.761 ± 0.352
1.142PheTyr: 1.142 ± 0.443
0.0PheXaa: 0.0 ± 0.0
Gly
5.329GlyAla: 5.329 ± 0.524
1.523GlyCys: 1.523 ± 0.705
3.807GlyAsp: 3.807 ± 1.152
2.665GlyGlu: 2.665 ± 0.709
3.426GlyPhe: 3.426 ± 0.614
8.755GlyGly: 8.755 ± 7.605
0.761GlyHis: 0.761 ± 0.352
1.523GlyIle: 1.523 ± 0.267
4.187GlyLys: 4.187 ± 2.919
3.045GlyLeu: 3.045 ± 0.533
1.903GlyMet: 1.903 ± 0.804
3.045GlyAsn: 3.045 ± 0.533
2.665GlyPro: 2.665 ± 3.624
1.523GlyGln: 1.523 ± 0.267
4.949GlyArg: 4.949 ± 0.348
2.665GlySer: 2.665 ± 0.262
4.568GlyThr: 4.568 ± 3.714
3.426GlyVal: 3.426 ± 1.586
1.903GlyTrp: 1.903 ± 0.881
1.903GlyTyr: 1.903 ± 0.09
0.0GlyXaa: 0.0 ± 0.0
His
0.761HisAla: 0.761 ± 0.619
0.761HisCys: 0.761 ± 0.619
1.142HisAsp: 1.142 ± 0.529
0.761HisGlu: 0.761 ± 0.352
1.903HisPhe: 1.903 ± 0.881
2.284HisGly: 2.284 ± 0.886
1.142HisHis: 1.142 ± 0.443
1.903HisIle: 1.903 ± 0.881
1.142HisLys: 1.142 ± 0.443
2.665HisLeu: 2.665 ± 0.709
0.761HisMet: 0.761 ± 0.619
0.381HisAsn: 0.381 ± 0.176
2.284HisPro: 2.284 ± 1.057
1.523HisGln: 1.523 ± 0.705
1.903HisArg: 1.903 ± 1.062
2.665HisSer: 2.665 ± 0.262
2.284HisThr: 2.284 ± 1.057
0.381HisVal: 0.381 ± 0.176
0.0HisTrp: 0.0 ± 0.0
1.142HisTyr: 1.142 ± 0.529
0.0HisXaa: 0.0 ± 0.0
Ile
3.045IleAla: 3.045 ± 0.438
0.761IleCys: 0.761 ± 0.352
3.807IleAsp: 3.807 ± 0.181
6.091IleGlu: 6.091 ± 1.848
1.523IlePhe: 1.523 ± 0.267
3.426IleGly: 3.426 ± 1.586
1.903IleHis: 1.903 ± 0.09
5.71IleIle: 5.71 ± 0.271
5.329IleLys: 5.329 ± 1.419
4.187IleLeu: 4.187 ± 0.967
3.045IleMet: 3.045 ± 0.141
1.903IleAsn: 1.903 ± 0.09
3.426IlePro: 3.426 ± 0.614
0.761IleGln: 0.761 ± 0.619
2.665IleArg: 2.665 ± 1.234
4.568IleSer: 4.568 ± 0.172
3.045IleThr: 3.045 ± 0.438
1.523IleVal: 1.523 ± 0.705
0.381IleTrp: 0.381 ± 0.176
1.142IleTyr: 1.142 ± 0.443
0.0IleXaa: 0.0 ± 0.0
Lys
4.949LysAla: 4.949 ± 1.319
0.761LysCys: 0.761 ± 0.352
3.807LysAsp: 3.807 ± 1.762
3.807LysGlu: 3.807 ± 0.791
3.426LysPhe: 3.426 ± 0.614
3.807LysGly: 3.807 ± 3.095
1.142LysHis: 1.142 ± 0.443
4.949LysIle: 4.949 ± 2.291
4.949LysLys: 4.949 ± 1.595
3.426LysLeu: 3.426 ± 0.614
2.665LysMet: 2.665 ± 0.709
2.665LysAsn: 2.665 ± 1.234
1.523LysPro: 1.523 ± 0.267
2.284LysGln: 2.284 ± 0.086
4.568LysArg: 4.568 ± 0.172
4.949LysSer: 4.949 ± 2.567
4.187LysThr: 4.187 ± 0.005
4.949LysVal: 4.949 ± 1.319
1.142LysTrp: 1.142 ± 0.529
1.142LysTyr: 1.142 ± 0.529
0.0LysXaa: 0.0 ± 0.0
Leu
5.329LeuAla: 5.329 ± 1.419
1.903LeuCys: 1.903 ± 0.881
3.045LeuAsp: 3.045 ± 0.438
6.471LeuGlu: 6.471 ± 0.081
4.568LeuPhe: 4.568 ± 2.115
3.807LeuGly: 3.807 ± 1.762
4.568LeuHis: 4.568 ± 1.143
4.187LeuIle: 4.187 ± 4.862
7.994LeuLys: 7.994 ± 2.729
4.949LeuLeu: 4.949 ± 1.319
2.665LeuMet: 2.665 ± 0.709
3.045LeuAsn: 3.045 ± 0.438
2.665LeuPro: 2.665 ± 1.681
1.903LeuGln: 1.903 ± 0.881
5.329LeuArg: 5.329 ± 0.524
6.471LeuSer: 6.471 ± 0.89
6.091LeuThr: 6.091 ± 0.095
5.329LeuVal: 5.329 ± 0.524
2.284LeuTrp: 2.284 ± 0.086
2.665LeuTyr: 2.665 ± 0.262
0.0LeuXaa: 0.0 ± 0.0
Met
1.142MetAla: 1.142 ± 0.443
0.761MetCys: 0.761 ± 1.591
1.142MetAsp: 1.142 ± 0.529
3.045MetGlu: 3.045 ± 0.438
1.523MetPhe: 1.523 ± 0.705
1.903MetGly: 1.903 ± 0.881
1.903MetHis: 1.903 ± 0.881
1.903MetIle: 1.903 ± 0.881
1.142MetLys: 1.142 ± 0.443
2.284MetLeu: 2.284 ± 1.057
1.142MetMet: 1.142 ± 0.529
1.142MetAsn: 1.142 ± 0.443
0.761MetPro: 0.761 ± 0.352
1.142MetGln: 1.142 ± 0.443
3.807MetArg: 3.807 ± 0.181
3.045MetSer: 3.045 ± 1.505
1.523MetThr: 1.523 ± 1.238
1.903MetVal: 1.903 ± 0.881
0.381MetTrp: 0.381 ± 0.176
0.381MetTyr: 0.381 ± 0.176
0.0MetXaa: 0.0 ± 0.0
Asn
1.903AsnAla: 1.903 ± 1.062
0.761AsnCys: 0.761 ± 0.352
1.142AsnAsp: 1.142 ± 0.443
0.761AsnGlu: 0.761 ± 0.619
2.284AsnPhe: 2.284 ± 1.057
1.523AsnGly: 1.523 ± 1.238
0.381AsnHis: 0.381 ± 0.176
2.665AsnIle: 2.665 ± 1.234
1.903AsnLys: 1.903 ± 0.881
3.426AsnLeu: 3.426 ± 0.357
0.761AsnMet: 0.761 ± 0.352
1.142AsnAsn: 1.142 ± 0.529
3.426AsnPro: 3.426 ± 1.329
1.523AsnGln: 1.523 ± 0.705
1.903AsnArg: 1.903 ± 0.881
2.665AsnSer: 2.665 ± 0.262
2.284AsnThr: 2.284 ± 0.086
1.523AsnVal: 1.523 ± 0.267
0.761AsnTrp: 0.761 ± 0.352
0.761AsnTyr: 0.761 ± 0.352
0.0AsnXaa: 0.0 ± 0.0
Pro
3.426ProAla: 3.426 ± 3.272
0.381ProCys: 0.381 ± 0.176
4.187ProAsp: 4.187 ± 0.967
3.426ProGlu: 3.426 ± 2.3
3.426ProPhe: 3.426 ± 1.586
4.187ProGly: 4.187 ± 1.948
0.761ProHis: 0.761 ± 0.352
2.284ProIle: 2.284 ± 1.857
1.142ProLys: 1.142 ± 0.443
1.903ProLeu: 1.903 ± 0.881
1.142ProMet: 1.142 ± 0.529
0.381ProAsn: 0.381 ± 0.795
3.045ProPro: 3.045 ± 0.438
3.045ProGln: 3.045 ± 0.438
1.523ProArg: 1.523 ± 1.238
3.426ProSer: 3.426 ± 0.357
3.426ProThr: 3.426 ± 0.357
1.523ProVal: 1.523 ± 1.238
0.761ProTrp: 0.761 ± 0.352
0.381ProTyr: 0.381 ± 0.795
0.0ProXaa: 0.0 ± 0.0
Gln
2.665GlnAla: 2.665 ± 2.652
0.0GlnCys: 0.0 ± 0.0
0.381GlnAsp: 0.381 ± 0.795
2.665GlnGlu: 2.665 ± 0.262
1.142GlnPhe: 1.142 ± 0.529
1.903GlnGly: 1.903 ± 1.062
3.045GlnHis: 3.045 ± 0.438
1.903GlnIle: 1.903 ± 0.881
3.426GlnLys: 3.426 ± 0.614
4.187GlnLeu: 4.187 ± 0.005
1.142GlnMet: 1.142 ± 0.529
0.381GlnAsn: 0.381 ± 0.176
0.381GlnPro: 0.381 ± 0.795
0.381GlnGln: 0.381 ± 0.176
0.761GlnArg: 0.761 ± 0.352
1.903GlnSer: 1.903 ± 0.09
1.903GlnThr: 1.903 ± 0.09
1.903GlnVal: 1.903 ± 0.09
0.381GlnTrp: 0.381 ± 0.176
1.142GlnTyr: 1.142 ± 0.529
0.0GlnXaa: 0.0 ± 0.0
Arg
6.471ArgAla: 6.471 ± 0.081
0.761ArgCys: 0.761 ± 0.352
4.568ArgAsp: 4.568 ± 1.143
5.71ArgGlu: 5.71 ± 0.7
1.523ArgPhe: 1.523 ± 0.705
4.187ArgGly: 4.187 ± 0.976
1.142ArgHis: 1.142 ± 0.443
4.568ArgIle: 4.568 ± 1.143
4.187ArgLys: 4.187 ± 0.005
5.329ArgLeu: 5.329 ± 0.447
1.903ArgMet: 1.903 ± 1.062
2.665ArgAsn: 2.665 ± 0.709
1.903ArgPro: 1.903 ± 0.09
1.903ArgGln: 1.903 ± 0.881
1.523ArgArg: 1.523 ± 0.705
6.091ArgSer: 6.091 ± 2.038
2.665ArgThr: 2.665 ± 1.234
4.568ArgVal: 4.568 ± 0.8
1.142ArgTrp: 1.142 ± 0.529
1.142ArgTyr: 1.142 ± 0.529
0.0ArgXaa: 0.0 ± 0.0
Ser
5.329SerAla: 5.329 ± 0.447
1.142SerCys: 1.142 ± 0.443
3.807SerAsp: 3.807 ± 2.124
4.568SerGlu: 4.568 ± 1.143
1.903SerPhe: 1.903 ± 0.881
3.045SerGly: 3.045 ± 3.448
0.381SerHis: 0.381 ± 0.176
3.426SerIle: 3.426 ± 0.614
4.187SerLys: 4.187 ± 0.976
8.755SerLeu: 8.755 ± 0.805
2.665SerMet: 2.665 ± 0.709
1.523SerAsn: 1.523 ± 0.267
1.523SerPro: 1.523 ± 0.267
2.284SerGln: 2.284 ± 0.886
6.852SerArg: 6.852 ± 1.686
6.091SerSer: 6.091 ± 0.876
3.426SerThr: 3.426 ± 0.357
4.187SerVal: 4.187 ± 0.967
1.523SerTrp: 1.523 ± 0.705
4.568SerTyr: 4.568 ± 0.172
0.0SerXaa: 0.0 ± 0.0
Thr
4.568ThrAla: 4.568 ± 1.771
1.142ThrCys: 1.142 ± 0.529
3.045ThrAsp: 3.045 ± 0.533
4.568ThrGlu: 4.568 ± 2.115
1.903ThrPhe: 1.903 ± 0.09
3.807ThrGly: 3.807 ± 1.152
1.523ThrHis: 1.523 ± 0.705
4.949ThrIle: 4.949 ± 1.319
2.665ThrLys: 2.665 ± 0.262
8.755ThrLeu: 8.755 ± 1.138
1.523ThrMet: 1.523 ± 0.705
4.949ThrAsn: 4.949 ± 0.624
4.187ThrPro: 4.187 ± 1.948
1.142ThrGln: 1.142 ± 0.443
4.568ThrArg: 4.568 ± 0.8
3.426ThrSer: 3.426 ± 0.357
3.426ThrThr: 3.426 ± 1.329
3.426ThrVal: 3.426 ± 0.614
0.381ThrTrp: 0.381 ± 0.176
1.523ThrTyr: 1.523 ± 0.705
0.0ThrXaa: 0.0 ± 0.0
Val
3.426ValAla: 3.426 ± 1.329
0.381ValCys: 0.381 ± 0.176
4.187ValAsp: 4.187 ± 0.967
4.187ValGlu: 4.187 ± 1.948
1.142ValPhe: 1.142 ± 0.443
3.426ValGly: 3.426 ± 0.614
0.381ValHis: 0.381 ± 0.795
3.045ValIle: 3.045 ± 0.438
2.665ValLys: 2.665 ± 1.234
5.329ValLeu: 5.329 ± 0.524
1.523ValMet: 1.523 ± 0.705
1.523ValAsn: 1.523 ± 0.705
1.523ValPro: 1.523 ± 0.267
1.903ValGln: 1.903 ± 0.881
3.045ValArg: 3.045 ± 0.438
4.949ValSer: 4.949 ± 1.319
5.71ValThr: 5.71 ± 0.7
5.329ValVal: 5.329 ± 0.524
1.142ValTrp: 1.142 ± 0.529
1.903ValTyr: 1.903 ± 0.09
0.0ValXaa: 0.0 ± 0.0
Trp
1.142TrpAla: 1.142 ± 0.443
0.761TrpCys: 0.761 ± 0.352
0.381TrpAsp: 0.381 ± 0.176
1.523TrpGlu: 1.523 ± 0.705
1.523TrpPhe: 1.523 ± 0.705
0.761TrpGly: 0.761 ± 0.352
0.381TrpHis: 0.381 ± 0.176
0.381TrpIle: 0.381 ± 0.176
1.142TrpLys: 1.142 ± 0.529
1.142TrpLeu: 1.142 ± 0.443
0.761TrpMet: 0.761 ± 0.352
0.761TrpAsn: 0.761 ± 0.352
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.523TrpArg: 1.523 ± 0.705
0.761TrpSer: 0.761 ± 0.352
0.381TrpThr: 0.381 ± 0.176
0.381TrpVal: 0.381 ± 0.176
0.0TrpTrp: 0.0 ± 0.0
1.523TrpTyr: 1.523 ± 0.705
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.381TyrCys: 0.381 ± 0.176
2.284TyrAsp: 2.284 ± 1.057
2.665TyrGlu: 2.665 ± 1.234
0.761TyrPhe: 0.761 ± 0.352
1.523TyrGly: 1.523 ± 0.705
1.142TyrHis: 1.142 ± 0.443
2.284TyrIle: 2.284 ± 0.086
1.523TyrLys: 1.523 ± 0.705
2.284TyrLeu: 2.284 ± 0.086
1.142TyrMet: 1.142 ± 0.443
2.284TyrAsn: 2.284 ± 0.086
1.142TyrPro: 1.142 ± 0.443
0.761TyrGln: 0.761 ± 0.619
2.284TyrArg: 2.284 ± 1.057
1.903TyrSer: 1.903 ± 2.033
1.903TyrThr: 1.903 ± 0.881
2.284TyrVal: 2.284 ± 1.057
0.381TyrTrp: 0.381 ± 0.176
0.761TyrTyr: 0.761 ± 0.352
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2628 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski