Amino acid dipepetide frequency for Parafilimonas terrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.589AlaAla: 7.589 ± 0.099	0.852AlaCys: 0.852 ± 0.028	4.569AlaAsp: 4.569 ± 0.057	4.234AlaGlu: 4.234 ± 0.067	3.768AlaPhe: 3.768 ± 0.059	6.085AlaGly: 6.085 ± 0.081	1.264AlaHis: 1.264 ± 0.032	5.499AlaIle: 5.499 ± 0.06	4.744AlaLys: 4.744 ± 0.06	7.12AlaLeu: 7.12 ± 0.085	1.814AlaMet: 1.814 ± 0.037	3.894AlaAsn: 3.894 ± 0.052	2.437AlaPro: 2.437 ± 0.042	2.869AlaGln: 2.869 ± 0.048	2.466AlaArg: 2.466 ± 0.039	4.799AlaSer: 4.799 ± 0.063	4.166AlaThr: 4.166 ± 0.072	5.226AlaVal: 5.226 ± 0.062	0.925AlaTrp: 0.925 ± 0.026	2.989AlaTyr: 2.989 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.624CysAla: 0.624 ± 0.023	0.193CysCys: 0.193 ± 0.011	0.456CysAsp: 0.456 ± 0.022	0.416CysGlu: 0.416 ± 0.019	0.543CysPhe: 0.543 ± 0.019	0.713CysGly: 0.713 ± 0.025	0.206CysHis: 0.206 ± 0.013	0.824CysIle: 0.824 ± 0.023	0.518CysLys: 0.518 ± 0.02	0.855CysLeu: 0.855 ± 0.025	0.242CysMet: 0.242 ± 0.013	0.583CysAsn: 0.583 ± 0.021	0.341CysPro: 0.341 ± 0.017	0.187CysGln: 0.187 ± 0.013	0.332CysArg: 0.332 ± 0.015	0.626CysSer: 0.626 ± 0.023	0.519CysThr: 0.519 ± 0.02	0.516CysVal: 0.516 ± 0.018	0.11CysTrp: 0.11 ± 0.009	0.397CysTyr: 0.397 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.67AspAla: 4.67 ± 0.062	0.444AspCys: 0.444 ± 0.019	3.007AspAsp: 3.007 ± 0.053	3.706AspGlu: 3.706 ± 0.054	3.017AspPhe: 3.017 ± 0.054	3.902AspGly: 3.902 ± 0.074	0.861AspHis: 0.861 ± 0.027	4.32AspIle: 4.32 ± 0.06	4.125AspLys: 4.125 ± 0.065	4.191AspLeu: 4.191 ± 0.06	1.185AspMet: 1.185 ± 0.03	3.137AspAsn: 3.137 ± 0.052	1.755AspPro: 1.755 ± 0.038	1.116AspGln: 1.116 ± 0.034	1.61AspArg: 1.61 ± 0.033	3.334AspSer: 3.334 ± 0.064	2.763AspThr: 2.763 ± 0.046	3.674AspVal: 3.674 ± 0.05	0.785AspTrp: 0.785 ± 0.025	2.704AspTyr: 2.704 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.289GluAla: 4.289 ± 0.059	0.366GluCys: 0.366 ± 0.015	2.967GluAsp: 2.967 ± 0.051	3.63GluGlu: 3.63 ± 0.07	2.256GluPhe: 2.256 ± 0.04	3.241GluGly: 3.241 ± 0.047	1.081GluHis: 1.081 ± 0.031	4.109GluIle: 4.109 ± 0.062	5.013GluLys: 5.013 ± 0.077	5.133GluLeu: 5.133 ± 0.075	1.484GluMet: 1.484 ± 0.029	3.522GluAsn: 3.522 ± 0.044	1.6GluPro: 1.6 ± 0.029	2.329GluGln: 2.329 ± 0.047	2.346GluArg: 2.346 ± 0.051	2.598GluSer: 2.598 ± 0.045	3.131GluThr: 3.131 ± 0.05	3.196GluVal: 3.196 ± 0.05	0.791GluTrp: 0.791 ± 0.025	2.167GluTyr: 2.167 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.488PheAla: 3.488 ± 0.05	0.559PheCys: 0.559 ± 0.019	2.861PheAsp: 2.861 ± 0.048	2.627PheGlu: 2.627 ± 0.043	2.763PhePhe: 2.763 ± 0.048	3.268PheGly: 3.268 ± 0.059	0.834PheHis: 0.834 ± 0.024	4.196PheIle: 4.196 ± 0.066	3.253PheLys: 3.253 ± 0.053	4.3PheLeu: 4.3 ± 0.067	1.106PheMet: 1.106 ± 0.03	3.268PheAsn: 3.268 ± 0.046	1.786PhePro: 1.786 ± 0.034	1.329PheGln: 1.329 ± 0.032	1.69PheArg: 1.69 ± 0.038	3.765PheSer: 3.765 ± 0.052	3.202PheThr: 3.202 ± 0.049	2.795PheVal: 2.795 ± 0.049	0.606PheTrp: 0.606 ± 0.02	2.224PheTyr: 2.224 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.572GlyAla: 4.572 ± 0.073	0.711GlyCys: 0.711 ± 0.031	3.419GlyAsp: 3.419 ± 0.052	3.369GlyGlu: 3.369 ± 0.058	3.605GlyPhe: 3.605 ± 0.053	4.716GlyGly: 4.716 ± 0.089	1.141GlyHis: 1.141 ± 0.027	5.387GlyIle: 5.387 ± 0.069	5.245GlyLys: 5.245 ± 0.059	5.824GlyLeu: 5.824 ± 0.066	1.645GlyMet: 1.645 ± 0.039	4.162GlyAsn: 4.162 ± 0.076	1.502GlyPro: 1.502 ± 0.032	1.804GlyGln: 1.804 ± 0.041	2.422GlyArg: 2.422 ± 0.042	4.219GlySer: 4.219 ± 0.069	3.755GlyThr: 3.755 ± 0.082	3.994GlyVal: 3.994 ± 0.059	1.08GlyTrp: 1.08 ± 0.028	3.208GlyTyr: 3.208 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.4HisAla: 1.4 ± 0.033	0.216HisCys: 0.216 ± 0.011	0.975HisAsp: 0.975 ± 0.028	1.032HisGlu: 1.032 ± 0.028	1.177HisPhe: 1.177 ± 0.031	1.111HisGly: 1.111 ± 0.029	0.532HisHis: 0.532 ± 0.022	1.556HisIle: 1.556 ± 0.032	1.149HisLys: 1.149 ± 0.028	1.828HisLeu: 1.828 ± 0.037	0.276HisMet: 0.276 ± 0.013	1.1HisAsn: 1.1 ± 0.031	0.993HisPro: 0.993 ± 0.025	0.596HisGln: 0.596 ± 0.02	0.686HisArg: 0.686 ± 0.022	1.112HisSer: 1.112 ± 0.027	1.068HisThr: 1.068 ± 0.031	1.033HisVal: 1.033 ± 0.026	0.267HisTrp: 0.267 ± 0.015	0.925HisTyr: 0.925 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.254IleAla: 6.254 ± 0.076	0.785IleCys: 0.785 ± 0.023	4.337IleAsp: 4.337 ± 0.058	4.365IleGlu: 4.365 ± 0.057	3.308IlePhe: 3.308 ± 0.065	4.468IleGly: 4.468 ± 0.061	1.426IleHis: 1.426 ± 0.029	6.098IleIle: 6.098 ± 0.085	5.58IleLys: 5.58 ± 0.067	6.046IleLeu: 6.046 ± 0.073	1.406IleMet: 1.406 ± 0.038	5.036IleAsn: 5.036 ± 0.063	3.07IlePro: 3.07 ± 0.047	2.446IleGln: 2.446 ± 0.042	2.59IleArg: 2.59 ± 0.048	5.055IleSer: 5.055 ± 0.063	4.98IleThr: 4.98 ± 0.075	4.403IleVal: 4.403 ± 0.06	0.695IleTrp: 0.695 ± 0.021	2.853IleTyr: 2.853 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.375LysAla: 5.375 ± 0.07	0.381LysCys: 0.381 ± 0.018	4.438LysAsp: 4.438 ± 0.063	4.903LysGlu: 4.903 ± 0.074	2.64LysPhe: 2.64 ± 0.043	4.287LysGly: 4.287 ± 0.051	1.422LysHis: 1.422 ± 0.03	5.337LysIle: 5.337 ± 0.071	5.983LysLys: 5.983 ± 0.083	6.157LysLeu: 6.157 ± 0.074	1.846LysMet: 1.846 ± 0.036	4.852LysAsn: 4.852 ± 0.06	2.927LysPro: 2.927 ± 0.045	3.398LysGln: 3.398 ± 0.05	2.743LysArg: 2.743 ± 0.047	3.563LysSer: 3.563 ± 0.054	4.506LysThr: 4.506 ± 0.06	3.824LysVal: 3.824 ± 0.051	0.903LysTrp: 0.903 ± 0.024	2.962LysTyr: 2.962 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	6.222LeuAla: 6.222 ± 0.075	0.874LeuCys: 0.874 ± 0.026	4.227LeuAsp: 4.227 ± 0.062	4.358LeuGlu: 4.358 ± 0.066	4.761LeuPhe: 4.761 ± 0.075	5.03LeuGly: 5.03 ± 0.07	1.972LeuHis: 1.972 ± 0.037	6.416LeuIle: 6.416 ± 0.085	6.964LeuLys: 6.964 ± 0.073	9.117LeuLeu: 9.117 ± 0.103	2.168LeuMet: 2.168 ± 0.041	5.764LeuAsn: 5.764 ± 0.066	4.093LeuPro: 4.093 ± 0.051	4.315LeuGln: 4.315 ± 0.067	3.402LeuArg: 3.402 ± 0.05	6.406LeuSer: 6.406 ± 0.072	4.926LeuThr: 4.926 ± 0.061	4.715LeuVal: 4.715 ± 0.069	0.95LeuTrp: 0.95 ± 0.028	3.522LeuTyr: 3.522 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	1.716MetAla: 1.716 ± 0.039	0.183MetCys: 0.183 ± 0.012	1.045MetAsp: 1.045 ± 0.022	1.221MetGlu: 1.221 ± 0.031	0.913MetPhe: 0.913 ± 0.024	1.375MetGly: 1.375 ± 0.038	0.611MetHis: 0.611 ± 0.02	1.456MetIle: 1.456 ± 0.034	1.941MetLys: 1.941 ± 0.037	2.288MetLeu: 2.288 ± 0.042	0.666MetMet: 0.666 ± 0.024	1.458MetAsn: 1.458 ± 0.03	1.275MetPro: 1.275 ± 0.032	1.396MetGln: 1.396 ± 0.033	1.014MetArg: 1.014 ± 0.03	1.225MetSer: 1.225 ± 0.027	0.919MetThr: 0.919 ± 0.026	1.269MetVal: 1.269 ± 0.032	0.21MetTrp: 0.21 ± 0.013	0.814MetTyr: 0.814 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.839AsnAla: 4.839 ± 0.056	0.528AsnCys: 0.528 ± 0.021	3.624AsnAsp: 3.624 ± 0.056	3.543AsnGlu: 3.543 ± 0.055	2.906AsnPhe: 2.906 ± 0.055	4.271AsnGly: 4.271 ± 0.073	1.009AsnHis: 1.009 ± 0.028	5.31AsnIle: 5.31 ± 0.07	4.504AsnLys: 4.504 ± 0.058	4.788AsnLeu: 4.788 ± 0.061	1.327AsnMet: 1.327 ± 0.032	4.709AsnAsn: 4.709 ± 0.079	2.632AsnPro: 2.632 ± 0.05	1.771AsnGln: 1.771 ± 0.037	2.164AsnArg: 2.164 ± 0.041	3.47AsnSer: 3.47 ± 0.057	3.578AsnThr: 3.578 ± 0.064	3.52AsnVal: 3.52 ± 0.053	0.818AsnTrp: 0.818 ± 0.023	2.883AsnTyr: 2.883 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	3.446ProAla: 3.446 ± 0.057	0.256ProCys: 0.256 ± 0.015	2.662ProAsp: 2.662 ± 0.051	2.606ProGlu: 2.606 ± 0.041	1.99ProPhe: 1.99 ± 0.041	2.973ProGly: 2.973 ± 0.045	0.708ProHis: 0.708 ± 0.023	1.803ProIle: 1.803 ± 0.033	2.008ProLys: 2.008 ± 0.039	3.334ProLeu: 3.334 ± 0.046	0.745ProMet: 0.745 ± 0.02	1.825ProAsn: 1.825 ± 0.039	1.182ProPro: 1.182 ± 0.033	1.523ProGln: 1.523 ± 0.03	0.996ProArg: 0.996 ± 0.027	2.389ProSer: 2.389 ± 0.043	1.686ProThr: 1.686 ± 0.04	3.607ProVal: 3.607 ± 0.056	0.46ProTrp: 0.46 ± 0.018	1.6ProTyr: 1.6 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.565GlnAla: 2.565 ± 0.045	0.231GlnCys: 0.231 ± 0.012	1.448GlnAsp: 1.448 ± 0.033	1.719GlnGlu: 1.719 ± 0.032	1.78GlnPhe: 1.78 ± 0.037	1.815GlnGly: 1.815 ± 0.04	0.941GlnHis: 0.941 ± 0.029	2.116GlnIle: 2.116 ± 0.044	2.815GlnLys: 2.815 ± 0.042	3.981GlnLeu: 3.981 ± 0.062	0.949GlnMet: 0.949 ± 0.026	2.132GlnAsn: 2.132 ± 0.043	1.768GlnPro: 1.768 ± 0.041	2.683GlnGln: 2.683 ± 0.059	1.587GlnArg: 1.587 ± 0.034	2.288GlnSer: 2.288 ± 0.04	2.191GlnThr: 2.191 ± 0.036	2.149GlnVal: 2.149 ± 0.031	0.495GlnTrp: 0.495 ± 0.018	1.731GlnTyr: 1.731 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.133ArgAla: 2.133 ± 0.039	0.285ArgCys: 0.285 ± 0.013	1.761ArgAsp: 1.761 ± 0.04	1.911ArgGlu: 1.911 ± 0.044	1.969ArgPhe: 1.969 ± 0.034	1.986ArgGly: 1.986 ± 0.039	0.651ArgHis: 0.651 ± 0.025	2.94ArgIle: 2.94 ± 0.048	2.87ArgLys: 2.87 ± 0.049	3.535ArgLeu: 3.535 ± 0.047	1.039ArgMet: 1.039 ± 0.026	2.366ArgAsn: 2.366 ± 0.046	1.239ArgPro: 1.239 ± 0.033	1.518ArgGln: 1.518 ± 0.033	1.539ArgArg: 1.539 ± 0.035	2.091ArgSer: 2.091 ± 0.036	1.867ArgThr: 1.867 ± 0.033	2.008ArgVal: 2.008 ± 0.035	0.536ArgTrp: 0.536 ± 0.02	1.682ArgTyr: 1.682 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.66SerAla: 4.66 ± 0.065	0.647SerCys: 0.647 ± 0.02	3.097SerAsp: 3.097 ± 0.048	2.807SerGlu: 2.807 ± 0.042	3.898SerPhe: 3.898 ± 0.057	4.713SerGly: 4.713 ± 0.07	0.976SerHis: 0.976 ± 0.024	4.769SerIle: 4.769 ± 0.056	4.021SerLys: 4.021 ± 0.053	6.051SerLeu: 6.051 ± 0.071	1.324SerMet: 1.324 ± 0.029	3.642SerAsn: 3.642 ± 0.064	2.262SerPro: 2.262 ± 0.043	1.922SerGln: 1.922 ± 0.038	2.178SerArg: 2.178 ± 0.036	4.252SerSer: 4.252 ± 0.077	3.436SerThr: 3.436 ± 0.063	4.042SerVal: 4.042 ± 0.051	0.791SerTrp: 0.791 ± 0.022	2.604SerTyr: 2.604 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	5.011ThrAla: 5.011 ± 0.068	0.421ThrCys: 0.421 ± 0.016	3.234ThrAsp: 3.234 ± 0.048	2.903ThrGlu: 2.903 ± 0.05	2.511ThrPhe: 2.511 ± 0.044	4.858ThrGly: 4.858 ± 0.07	1.016ThrHis: 1.016 ± 0.026	4.543ThrIle: 4.543 ± 0.067	3.303ThrLys: 3.303 ± 0.045	4.97ThrLeu: 4.97 ± 0.066	0.97ThrMet: 0.97 ± 0.023	3.107ThrAsn: 3.107 ± 0.053	2.488ThrPro: 2.488 ± 0.051	1.839ThrGln: 1.839 ± 0.04	1.771ThrArg: 1.771 ± 0.041	3.576ThrSer: 3.576 ± 0.061	3.435ThrThr: 3.435 ± 0.064	3.932ThrVal: 3.932 ± 0.075	0.722ThrTrp: 0.722 ± 0.024	2.261ThrTyr: 2.261 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.531ValAla: 4.531 ± 0.064	0.711ValCys: 0.711 ± 0.025	3.097ValAsp: 3.097 ± 0.048	3.14ValGlu: 3.14 ± 0.047	3.133ValPhe: 3.133 ± 0.047	3.26ValGly: 3.26 ± 0.054	1.226ValHis: 1.226 ± 0.033	4.736ValIle: 4.736 ± 0.065	4.356ValLys: 4.356 ± 0.055	5.753ValLeu: 5.753 ± 0.067	1.517ValMet: 1.517 ± 0.032	3.676ValAsn: 3.676 ± 0.056	2.3ValPro: 2.3 ± 0.04	2.249ValGln: 2.249 ± 0.04	2.086ValArg: 2.086 ± 0.039	4.027ValSer: 4.027 ± 0.057	3.59ValThr: 3.59 ± 0.065	3.78ValVal: 3.78 ± 0.063	0.756ValTrp: 0.756 ± 0.022	2.606ValTyr: 2.606 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.754TrpAla: 0.754 ± 0.024	0.142TrpCys: 0.142 ± 0.008	0.673TrpAsp: 0.673 ± 0.024	0.594TrpGlu: 0.594 ± 0.023	0.617TrpPhe: 0.617 ± 0.024	0.832TrpGly: 0.832 ± 0.024	0.291TrpHis: 0.291 ± 0.014	0.83TrpIle: 0.83 ± 0.027	0.983TrpLys: 0.983 ± 0.025	1.326TrpLeu: 1.326 ± 0.036	0.427TrpMet: 0.427 ± 0.017	0.903TrpAsn: 0.903 ± 0.025	0.403TrpPro: 0.403 ± 0.016	0.649TrpGln: 0.649 ± 0.021	0.549TrpArg: 0.549 ± 0.021	0.656TrpSer: 0.656 ± 0.019	0.588TrpThr: 0.588 ± 0.021	0.699TrpVal: 0.699 ± 0.023	0.245TrpTrp: 0.245 ± 0.014	0.572TrpTyr: 0.572 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.171TyrAla: 3.171 ± 0.049	0.417TyrCys: 0.417 ± 0.017	2.41TyrAsp: 2.41 ± 0.049	2.164TyrGlu: 2.164 ± 0.041	2.365TyrPhe: 2.365 ± 0.044	2.875TyrGly: 2.875 ± 0.05	0.863TyrHis: 0.863 ± 0.025	2.957TyrIle: 2.957 ± 0.051	3.07TyrLys: 3.07 ± 0.047	3.607TyrLeu: 3.607 ± 0.058	0.857TyrMet: 0.857 ± 0.027	3.059TyrAsn: 3.059 ± 0.055	1.746TyrPro: 1.746 ± 0.034	1.445TyrGln: 1.445 ± 0.031	1.755TyrArg: 1.755 ± 0.034	2.642TyrSer: 2.642 ± 0.044	2.565TyrThr: 2.565 ± 0.049	2.148TyrVal: 2.148 ± 0.041	0.589TyrTrp: 0.589 ± 0.021	2.127TyrTyr: 2.127 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4249 proteins (1483638 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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